Nutrition Commons^™

Exploring The Short-Term Effects Of Probiotic And Prebiotic Supplementation On The Microbiota And Physiology Of Male C57bl/6 Mice, Miguel Angel Rivas

Wayne State University Theses

The gut microbiome may play a role in the development of chronic diseases like obesity, diabetes, and heart disease. Diets including prebiotics or probiotics can alter the abundance of gut bacterial groups and have subsequent health effects. In this study we wanted to establish a method for comparing the benefits of commercial supplements that alter the microbiota by monitoring fecal microbial profiles in male C57BL/6 mice (n = 24) exposed to 15 days of dietary supplementation. A probiotic diet (VSL#3) and a prebiotic diet (potato starch) were compared to a standard diet (n = 8 for each group). Microbial profiles …

The Effects Of Pre-Pregnancy Tobacco Use On Food Cravings And Weight Gain In Pregnancy, Lauren E. Blau

Legacy Theses & Dissertations (2009 - 2024)

Smoking cessation is associated with greater frequency of food cravings, even when controlling for body mass index. Recent studies have indicated similarities between obese women and women who smoke tobacco in mood states and food craving frequency. This is consistent with the common substrate hypothesis, which postulates that shared neural pathways mediate craving across multiple domains, and could explain why it is common for women attempting to quit smoking to gain weight. Smoking cessation prior to pregnancy is strongly encouraged due to the adverse effects of tobacco use on the developing fetus. Studies have shown that women who quit smoking …

Nitrate, The Oral Microbiome, And Cardiovascular Health: A Systematic Literature Review Of Human And Animal Studies, Lauren C. Blekkenhorst, Nicola P. Bondonno, Alex H. Liu, Natalie C. Ward, Richard L. Prince, Joshua R. Lewis, Amanda Devine, Kevin D. Croft, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2014 to 2021

Background

Dietary nitrate is an important source of nitric oxide (NO), a molecule critical for cardiovascular health. Nitrate is sequentially reduced to NO through an enterosalivary nitrate-nitrite-NO pathway that involves the oral microbiome. This pathway is considered an important adjunct pathway to the classical l-arginine–NO synthase pathway.

Objective

The objective of this study was to systematically assess the evidence for dietary nitrate intake and improved cardiovascular health from both human and animal studies.

Design

A systematic literature search was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines by using key search terms in Medline and …

Relationship Of Dietary Nitrate Intake From Vegetables With Cardiovascular Disease Mortality: A Prospective Study In A Cohort Of Older Australians, Alex H. Liu, Catherine P. Bondonno, Joanna Russell, Victoria M. Flood, Joshua R. Lewis, Kevin D. Croft, Richard J. Woodman, Wai H. Lim, Annette Kifley, Germaine Wong, Paul Mitchell, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2014 to 2021

Purpose: Short-term trials indicate inorganic nitrate and nitrate-rich vegetables may have vascular health benefits. However, few observational studies have explored the relationship between nitrate intake and long-term cardiovascular disease (CVD) outcomes. The primary aim of this study was to investigate the association of nitrate intake from vegetables with CVD mortality in a sample of older Australians.

Methods: A subgroup of participants without diabetes or major CVD at baseline (1992–1994) were included from the Blue Mountains Eye Study, a population-based cohort study of men and women aged ≥ 49 years. Diets were evaluated using a validated food frequency questionnaire at baseline, …

Daily Pork Consumption As A Part Of The Dietary Approaches To Stop Hypertension Diet Influences Body Composition And Preserves Muscle Mass In Older Adults Consuming Controlled Intakes, Alyssa Anne Kauffman

Electronic Theses and Dissertations

The purpose of this study was to test the hypothesis that muscular fitness is preserved in older adults who consumed pork daily as a part of the DASH dietary pattern. A controlled feeding pilot study was used to test this. Eight healthy older men and women were randomly assigned to consume either 3 ounces or 6 ounces of pork daily as a part of the DASH diet for a total of 12 weeks. Indicators of muscle mass, strength, and function were assessed at five time points (weeks 0, 3, 6, 9, 12) throughout the 12 weeks. A seven day cyclical …

Effects Of Yogurt Fortification With Different Legumes Protein On The Physio-Chemical, Microbiological, And Rheological Properties, Prachi Pahariya

Electronic Theses and Dissertations

Nowadays, yogurt (a nutritious fermented dairy product) is getting popular around all over the world due to beneficial action provided by bacteria present in yogurt culture. Along with that, diet plans, which are high in protein and low in fat, has become appealing for growing healthy conscious population that makes a huge shift toward plantbased protein consumption. Therefore, the main objective of this research was to study the effects of yogurt fortification with extracted protein of different beans (legumes)- pinto and kidney beans on the physio-chemical (Moisture, Fat, Protein, Ash, Total Solids Content (TSC), pH, Titratable Acidity (TA), Water Holding …

Comparison Of Air Displacement Plethysmography And Dual-Energy X-Ray Absorptiometry For Estimation Of Body Fat Percentage In National Collegiate Athletic Association Division I Athletes, Caitlyn Rose Chenevert

Electronic Theses and Dissertations

The aim of this research is to study the Apple iOS and Android mobile frameworks from a developers' perspective. The first chapter introduces a historical overview of operating systems for mobile devices as well the motivation and objectives of the research. The second chapter introduces basic principles of the iOS and Android mobile frameworks in order to evaluate the platforms. The third chapter evaluates and compares the main features of both frameworks. The fourth chapter discusses the implementation of several applications on the iOS and Android mobile frameworks, which are used to demonstrate the advantages and disadvantages of each platform. …

Food Insecurity And Physical And Mental Health Of Elementary School Children In A Rural, Appalachian Mississippi Community, Kelsey Reece Dismukes

Electronic Theses and Dissertations

Household food insecurity has been associated with poor physical health and behavioral and psychological problems in children. This study examined differences in parent/caregiver-perceived child health and parent/caregiver-reported behavioral and psychological problems by food security status of elementary school children (Kindergarten through 6th grade) living in rural, Appalachian Mississippi. This study used a cross-sectional survey of elementary school parents/caregivers recruited at three elementary schools in an economically-distressed Appalachian MS county. Data were analyzed using IBM SPSS (versions 23, 2015) to assess for differences in HLTH (t-test), BEHAV (Chi Square), and PSYCH (Chi Square) by household food security status. The relationship of …

The Effect Of Restaurant Menu Labeling On Attitudes Towards Menu Labeling And Eating Behaviors Of Ncaa Athletes, Recreational Athletes, And Non-Athletes’ In A University Setting, Virginia Mitchell

Electronic Theses and Dissertations

Intro College students eat the majority of their meals outside of the home, which likely means that college students are impacted by calories consumed in restaurants, including campus dining halls. The Affordable Care Act, while not fully operationalized, requires calorie content labels be included on menus and menu boards in restaurants so that consumers are aware of the calories of menu items selected. Therefore, it is important to explore college students, including athletes, attitudes and behaviors toward menu labeling in an on-campus dining facility setting. The objectives of this study were to determine NCAA athletes, recreational athletes, and non-athlete’s attitudes …

Vitamin Fortification Of Milled Rice: A New Approach To Address Micronutrient Malnutrition, Drexel H. Camacho

Angelo King Institute for Economic and Business Studies (AKI)

To address micronutrient deficiencies in the susceptible sector of society, it is recommended to fortify the commercial milled rice with vitamins using the new technique of fortification. The simple approach, which involves rice surface modification and vitamin absorption, is deemed economical compared to traditional fortification processes. Moreover, the susceptibility of losing vitamins due to washing processes is resolved in this improved grain fortification as ~90% of the vitamins are retained. The results shown in this study indicate the successful fortification of vitamins on rice and that fortification is more pronounced when the grain undergoes sonication process. As the staple food …

A Message From The Department Head Of Horticulture And Food Science, Wayne Mackey

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Using “Photovoice” To Identify Rural Community Food Issues, Lisa Franzen-Castle, Tara Shafrath, Lindsay Moore, Ann Schwader, Daniel T. Remley, Suzanne Stluka

Health and Nutritional Sciences Faculty Publications

Rural communities experience unique barriers to food security. Developing food policy councils (FPCs) is a systematic approach to address food security. FPCs bring together a diverse network of community stakeholders to address local food system strengths and concerns. A six-state team developed new or provided support to existing FPCs in rural communities. Photovoice is a project component used to engage youths, helped identify community food issues, such as food access and affordability in studied communities. Furthermore, it was meant to engage FPCs in meaningful dialogue to identify solutions, such as community gardens and work with local food pantries. Because of …

Preparation And Antimicrobial Activity Of Caprylic Acid Emulsion For Food Coating, Raweewan Bunyovimonnat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Antimicrobial food coating is the interesting method for food preservation, especially in fruits and vegetables. Previous studies have been reported that the caprylic acid had the antimicrobial activity against a variety of microorganisms. However, little research has been conducted on the use of caprylic acid in the form of food coatings. Therefore, this study aims to determine the optimum conditions for the caprylic acid emulsion preparation and to evaluate the antimicrobial activity of the emulsion, including the effect of food coatings with caprylic acid emulsion on physical properties and microbial growth inhibition. Emulsions containing 4% w/v caprylic acid (oil) and …

การพัฒนาแบบจำลองเซลล์ลำไส้ของมนุษย์บนกระดาษที่มีการดัดแปรพื้นผิวและต้นแบบไบโอเซนเซอร์ไร้สายสำหรับตรวจวัดการเจริญของจุลชีพก่อโรค, ปัณณวิชญ์ ถิรบวรกิจพิธาน

Chulalongkorn University Theses and Dissertations (Chula ETD)

วิทยานิพนธ์นี้เป็นการนำเสนองานวิจัย การพัฒนาวิธีการใหม่เพื่อควบคุมและเฝ้าระวังโรคติดเชื้อ โดยประกอบด้วยเนื้อหาสำคัญสองส่วน ได้แก่ (i) การพัฒนาแบบจำลองเซลล์ลำไส้ของมนุษย์ที่เพาะเลี้ยงบนกระดาษที่มีการดัดแปรพื้นผิว เพื่อใช้ประโยชน์ในการศึกษากลไกการบุกรุกของเชื้อจุลชีพก่อโรคในระบบทางเดินอาหาร และ (ii) การพัฒนาต้นแบบไบโอเซนเซอร์แบบไร้สายเพื่อการตรวจติดตามการเจริญของเชื้อจุลชีพก่อโรค โดยในส่วนแรก เซลล์ลำไส้ของมนุษย์ HT-29 จำนวน 200,000 เซลล์ ถูกเพาะเลี้ยงในบริเวณชอบน้ำของกระดาษกรอง Whatman No.1 โดยกระดาษถูกดัดแปรพื้นผิวด้วยสารแมทริกซ์นอกเซลล์ (Extracellular matrix: ECM) ชนิดต่าง ๆ ได้แก่ Matrigel, Collagen-1 และ Laminin พื้นที่เพาะเลี้ยงเซลล์มีขนาด 12.56 ตารางมิลลิเมตร ภายใต้สภาวะที่เหมาะสม เซลล์ HT-29 ที่ถูกเพาะเลี้ยงบนกระดาษ มีชีวิตรอดได้ถึง 28 วัน และแสดงลักษณะของเซลล์ที่เจริญเต็มที่ โดยมีการแสดงออกของวิลไล (villi) ที่ผิวเซลล์ด้านบน (apical) และมีการแสดงออกของโปรตีน ZO-1 ซึ่งแสดงถึงเซลล์มีการสร้างไทต์จังก์ชันเกิดขึ้น จากการใช้สารเชื่อมพันธะสำหรับเชื่อมพันธะ ECM แต่ละชนิด พบว่าเมื่อใช้สารเจนิพินในการเชื่อมพันธะ เซลล์มีชีวิตรอดทั้งหมด (100 -112.8%) ในขณะที่มีเพียง 1.1 - 67.3 % ของเซลล์รอดชีวิต หากใช้สารกลูตารัลดีไฮด์ในการเชื่อมพันธะ แต่การใช้สารเชื่อมพันธะทั้งสองชนิด ทำให้เซลล์ไม่สามารถแบ่งตัวมีรูปร่างแบบสามมิติได้ เมื่อสังเกตด้วย SEM เซลล์มีลักษณะแบน การดัดแปรพื้นผิวกระดาษด้วยสาร ECM ชนิด Matrigel ส่งผลให้เซลล์มีชีวิตรอดมากที่สุดและสาร ECM ชนิด Laminin ทำให้เซลล์เกิดการแปรสภาพ (cell differentiation) ได้ดีที่สุด งานวิจัยส่วนที่ 2 เป็นการพัฒนาไบโอเซนเซอร์ไร้สายสำหรับติดตามการเจริญของเชื้อจุลชีพก่อโรค ได้แก่ เชื้อ Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus gordonii และ Candida albicans พบว่าเชื้อดังกล่าวสามารถสร้างไบโอฟิล์มบนผิวของขั้วไฟฟ้าคาร์บอนอสัณฐาน (glassy carbon electrode) และสามารถให้ค่าศักย์ไฟฟ้าที่เป็นลบได้ …

Applications In Utilization Of Forage Chemical Composition And Predicting Equine Digestibility, Veronica Taylor Bill

Theses and Dissertations--Animal and Food Sciences

Most forage quality models were developed for ruminant nutrition, and may not apply to the horse. This two-part study evaluated the relationship between forage chemical composition and dry matter digestibility (DMD) using an in vitro method with equine feces as the inoculums. The first experiment determined that compared to 48 h of incubation, 72 h of incubation resulted in higher DMD for some forages. As a result of experiment 1, incubations in experiment 2 were conducted using 48 and 72 h incubation periods at 38 degrees C. The second experiment evaluated the effect of chemical composition on DMD. Thirty-one hay …

Vitamin D Works Through The Lipid Droplet Protein Plin2 To Augment Mitochondrial Function In Skeletal Muscle, David M. Schnell

Theses and Dissertations--Pharmacology and Nutritional Sciences

Vitamin D has been connected with increased intramyocellular lipid (IMCL) mitochondrial function in skeletal muscle. It is also shown to prevent lipotoxicity in several tissues, but this has not yet been examined in skeletal muscle. Perilipin 2 (PLIN2), a lipid droplet protein upregulated with vitamin D treatment, is integral to managing IMCL capacity and lipid oxidation in skeletal muscle. Increased lipid storage and oxidation is associated with increased tolerance to a hyperlipidic environment and resistance to lipotoxicity. Therefore, I hypothesized that vitamin D increases β-oxidation and lipid turnover though a PLIN2 mediated mechanism, thereby preventing lipotoxicity.

This hypothesis was divided …

Pcb Disruption Of Gut And Host Health: Implications Of Prebiotic Nutritional Intervention, Jessie Baldwin Hoffman

Theses and Dissertations--Pharmacology and Nutritional Sciences

Exposure to environmental pollutants poses numerous risk factors for human health, including increasing incidence of cardiovascular disease and diabetes. Persistent organic pollutants, such as polychlorinated biphenyls (PCBs) have been strongly linked to the development of these chronic inflammatory diseases and the primary route of exposure is through consumption of contaminated food products. Thus, the gastrointestinal tract is susceptible to the greatest levels of these pollutants and is an important facet to study.

The first two hypotheses of this dissertation tested that exposure to PCBs disrupts gut microbiota directly (in vitro) and within a whole body system. PCB exposure …

The Prebiotic Inulin Beneficially Modulates The Gut-Brain Axis By Enhancing Metabolism In An Apoe4 Mouse Model, Jared D. Hoffman

Theses and Dissertations--Pharmacology and Nutritional Sciences

Alzheimer’s disease (AD) is the most common form of dementia and a growing disease burden that has seen pharmacological interventions primarily fail. Instead, it has been suggested that preventative measures such as a healthy diet may be the best way in preventing AD. Prebiotics are one such potential measure and are fermented into metabolites by the gut microbiota and acting as gut-brain axis components, beneficially impact the brain. However, the impact of prebiotics in AD prevention is unknown. Here we show that the prebiotic inulin increased multiple gut-brain axis components such as scyllo-inositol and short chain fatty acids in the …

Towards A Healthier Chocolate Formula Which Is Rich In Polyphenols And Low In Fat, Lakmani Tharaka Galaniha

Theses and Dissertations--Nutrition and Food Systems

Chocolate is a food that is craved by many in the world and healthy chocolates have become a current topic in the healthy eating trend. The healthiness of a chocolate depends mainly on the polyphenol, fat and sugar contents. Although the literature serves several interventions to reduce the fat content and total calorie content of chocolates, it does not provide many interventions that consider both improving the polyphenol and reducing the fat content simultaneously. Considering this gap in the literature, this research project sought to develop a chocolate that is both low in fat and high in polyphenol content, without …

Cultural Sensitivity In Cooperative Extension Nutrition Education Programming In Kentucky, Anna Caroline Durr

Theses and Dissertations--Nutrition and Food Systems

The purpose of this mixed methods study was to learn how cultural sensitivity was integrated and perceived in community nutrition education of an existing program offered by the University of Kentucky Cooperative Extension Service Nutrition Education Program. Data collection consisted of a quantitative cultural competence assessment survey tool used with nutrition education paraprofessionals (n=74), qualitative in-depth interviews of nutrition education paraprofessionals (n=8) and focus groups of Hispanic/Latino nutrition education program participants (n=39). Findings were focused in three areas; the cultural sensitivity needs of the program, the perception of nutrition education by participants and the training and professional development needs of …