Other Nutrition Commons^™

Differential Progression Of Unhealthy Dietinduced Hepatocellular Carcinoma In Obese And Non-Obese Mice, Emma Hymel, Elizabeth Vlock, Kurt W. Fisher, Paraskevi A. Farazi

Nutrition and Health Sciences -- Faculty Publications

Background Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalence of lean NAFLD is 7 percent in the U.S. and 25–30 percent in some Asian countries. NAFLD starts with excess liver fat accumulation (NAFL), progresses to nonalcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). The pathogenesis of lean NASH-HCC and how it differs from obese NASH-HCC is not well understood.

Methods In this work, we generated a mouse model of lean and obese NASH-HCC using a …

Markers Of Fungal Translocation Are Elevated During Post-Acute Sequelae Of Sars-Cov-2 And Induce Nf-Κb Signaling, Leila B. Giron, Michael J. Peluso, Jianyi Ding, Grace Kenny, Netanel F. Zilberstein, Jane Koshy, Kai Ying Hong, Heather Rasmussen, Gregory E. Miller, Faraz Bishehsari, Robert A. Balk, James N. Moy, Rebecca Hoh, Scott Lu, Aaron R. Goldman, Hsin Yao Tang, Brandon C. Yee, Ahmed Chenna, John W. Winslow, Christos J. Petropoulos, J. Daniel Kelly, Haimanot Wasse, Jeffrey N. Martin, Qin Liu, Ali Keshavarzian, Alan Landay, Steven G. Deeks, Timothy J. Henrich, Mohamed Abdel-Mohsen

Nutrition and Health Sciences -- Faculty Publications

Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated with sustained elevated levels of immune activation and inflammation. However, the mechanisms that drive this inflammation remain unknown. Inflammation during acute coronavirus disease 2019 could be exacerbated by microbial translocation (from the gut and/or lung) to blood. Whether microbial translocation contributes to inflammation during PASC is unknown. We did not observe a significant elevation in plasma markers of bacterial translocation during PASC. However, we observed higher levels of fungal translocation - measured as β-glucan, a fungal cell wall polysaccharide - in the plasma of individuals experiencing PASC …

Microbial, Chemical, And Functional Components In Kefir, Natto, And Feed Ingredients, Dana Mccurdy

All Dissertations

Kefir grains were purchased from online, home kitchen vendors in the United States (n = 22), inoculated into UHT milk, and incubated at 25°C for 22 hours. Results indicated lactobacilli, lactococci and yeast in all samples. Six out of 11 samples contained coliform, and all samples contained pseudomonal and staphylococcal species. Using targeted genome sequencing (16S) of kefir grain samples 1, 2, and 3 revealed that lactobacilli were the predominant genera of bacteria. ITS sequencing revealed different fungal species in each grain. Results indicated potential presence of menaquinone-4 and menaquinone-7 by UPLC-MS/MS analysis.

The fermentation of whole and ground soybeans, …

The Development Of Video Podcast As An Innovation In Online Nutrition Education And Its Engagement Data Analysis, Lini Anisfatus Sholihah

ASEAN Journal of Community Engagement

Podcasts have become more popular in Indonesia recently. Studies have shown that video podcasts, which incorporate education and entertainment aspects, are effective as a medium to study language and medical subjects among students and clinicians. This study aims to analyze video podcasts’ utilization in nutrition education and how they can engage viewers from the general community. This paper further aims to describe the development of a video podcast, NutriPodcast, as an innovative media to educate the community regarding nutrition topics. The number of audience views was calculated by utilizing the analytical feature on social media. The methodology to develop the …

Sweet Taste Signaling: The Core Pathways And Regulatory Mechanisms, Sunil Kumar Sukumaran, Salin Raj Palayyan

Nutrition and Health Sciences -- Faculty Publications

Sweet taste, a proxy for sugar-derived calories, is an important driver of food intake, and animals have evolved robust molecular and cellular machinery for sweet taste signaling. The overconsumption of sugar-derived calories is a major driver of obesity and other metabolic diseases. A fine-grained appreciation of the dynamic regulation of sweet taste signaling mechanisms will be required for designing novel noncaloric sweeteners with better hedonic and metabolic profiles and improved consumer acceptance. Sweet taste receptor cells express at least two signaling pathways, one mediated by a heterodimeric G-protein coupled receptor encoded by taste 1 receptor members 2 and 3 (TAS1R2 …

The Effects Of Vitamin D Supplementation On Athletic Performance And Injury Prevention, Amani Adeeb Abushamma

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Vitamin D supplementation has numerous effects on athletic performance and plays a significant role in preventing an athlete’s risk of getting injuries. Vitamin D has an impact on numerous physiological functions such as: bone health, muscle function, inflammatory response, and immune function. An athlete’s bone and muscle health are essential for maximum performance and career success. A bone fracture due to vitamin D deficiency can delay an athlete’s training and ultimately inhibit obtaining a collegiate scholarship and/or contract. A cross sectional study found that more than half of athletic trainers did not view 25-hydroxyvitamin D(25[OH]) testing and vitamin D supplementation …

Time Course Of Changes In Torque And Neuromuscular Parameters During A Sustained Isometric Forearm Flexion Task To Fatigue Anchored To A Constant Rating Of Perceived Exertion, Robert W. Smith, Terry J. Housh, John Paul V. Anders, Tyler J. Neltner, Jocelyn E. Arnett, Richard Schmidt, Glen O. Johnson

Nutrition and Health Sciences -- Faculty Publications

Objective: This study examined the time course of changes in torque and electromyographic (EMG) and mechanomyographic (MMG) responses during a sustained isometric task anchored to a constant perception of exertion (RPE). Methods: Twelve college-aged men performed an isometric forearm flexion task to failure anchored to RPE=7 (OMNI-RES scale). The amplitude (AMP) and frequency (MPF) of the EMG and MMG signals from the biceps brachii were recorded. Repeated measures ANOVAs were used to examine differences for the normalized (%MVIC) torque and neuromuscular parameters. Results: The time to task failure (TTF) was 678.0±468.1s. Torque decreased significantly (p<0.001, η_p ²=0.774) …

Small Extracellular Vesicles In Milk Cross The Blood-Brain Barrier In Murine Cerebral Cortex Endothelial Cells And Promote Dendritic Complexity In The Hippocampus And Brain Function In C57bl/6j Mice, Fang Zhou, Pearl Ebea, Ezra Mutai, Haichuan Wang, Sonal Sukreet, Shya Navazesh, Haluk Dogan, Wenhao Li, Juan Cui, Peng Ji, Denise M.O. Ramirez, Janos Zempleni

Nutrition and Health Sciences -- Faculty Publications

Human milk contains large amounts of small extracellular vesicles (sEVs) and their microRNA cargos, whereas infant formulas contain only trace amounts of sEVs and microRNAs. We assessed the transport of sEVs across the blood-brain barrier (BBB) and sEV accumulation in distinct regions of the brain in brain endothelial cells and suckling mice. We further assessed sEV-dependent gene expression profiles and effects on the dendritic complexity of hippocampal granule cells and phenotypes of EV depletion in neonate, juvenile and adult mice. The transfer of sEVs across the BBB was assessed by using fluorophore-labeled bovine sEVs in brain endothelial bEnd.3 monolayers and …

Burden Of Food Insecurity Among College Students: A Cross-Sectional Study During The Covid-19 Pandemic, Saba Sami

Electronic Theses, Projects, and Dissertations

Background: Food insecurity is lack of access to proper nutrition for an individual to obtain a healthy lifestyle. The goal of this research is to determine the frequency of food insecurity among college students at a four-year college institution during COVID-19 pandemic in association to mental and physical health status.

Methods: This study was conducted among college students using cross-sectional study method. All data were collection virtually and kept anonymous. All statistical analyses were conducted using SPSS version 28 with (p<.05), denoting significance.

Results: In the study there were a total of 98 participants who were being analyzed. All the participants were …

Does A Hypertrophying Muscle Fibre Reprogramme Its Metabolism Similar To A Cancer Cell?, Henning Wackerhage, Ivan J. Vechetti, Philipp Baumert, Sebastian Gehlert, Lore Becker, Richard T. Jaspers, Martin Hrabě De Angelis

Nutrition and Health Sciences -- Faculty Publications

In 1924, Otto Warburg asked “How does the metabolism of a growing tissue differ from that of a non-growing tissue?” Currently, we know that proliferating healthy and cancer cells reprogramme their metabolism. This typically includes increased glucose uptake, glycolytic flux and lactate synthesis. A key function of this reprogramming is to channel glycolytic intermediates and other metabolites into anabolic reactions such as nucleotide-RNA/DNA synthesis, amino acid-protein synthesis and the synthesis of, for example, acetyl and methyl groups for epigenetic modification. In this review, we discuss evidence that a hypertrophying muscle similarly takes up more glucose and reprogrammes its metabolism to …

Food For Thought: The Relationship Between Nutrition And Academic Performance, Sarah Freeman

Honors Projects in Science and Technology

Nutrition has been shown to impact the level of cognitive function in individuals. Through the analysis of nutritional diets, this new research will aim to uncover the impact that diet has on cognitive function of Bryant University students by analyzing their ability to perform on a variety of cognitive assessments. This study will provide recommendations to students at Bryant University on what they should eat so they can perform their best academically. This research will also investigate whether Bryant University is offering the best food for students to eat setting them up for success.

Plant Wise, Sophia Llamas

Honors Projects

Conceptually, Plant Wise is the key to bridging the gap between preconceived ideas about vegan and vegetarianism and successfully integrating plant-based foods into your everyday life. Physically, Plant Wise is a self-educational, interactive booklet chock-full of activities intended for users to complete at their own pace. Inside this 56-page booklet, there are recipes, doodling spaces, weekly check sheets, activities to do with friends and family, challenges, and so much more. Plant Wise utilizes these activities and journaling opportunities throughout as a self-reflective vehicle to give users an experience to reflect on, which aids in the retention of what’s been learned …

Evaluation Of Nutrition Intervention In The Senior Population, Stephanie K. Fonseca

Department of Nutrition Student Projects

Average life expectancy has steadily increased with each passing year and is estimated to continue increasing in years to come. Reports show that the number of people aged 65 or older has increased from 6% of the population in the 1960’s, to 12% in the year 2000, to 16% of the total population in 2015.¹ This number is expected to increase to almost 20% of the population by the year 2050.¹ Striving towards healthy aging can help the growing senior population to live the best possible life in their later years. Nutrition education is one area of learning …

“Many People Have No Idea”: A Qualitative Analysis Of Healthcare Barriers Among Yazidi Refugees In The Midwestern United States, Falah Rashoka, Megan S. Kelley, Jeong‑Kyun Choi, Marc A. Garcia, Weiwen Chai, Hazim N. Rashawka

Nutrition and Health Sciences -- Faculty Publications

Background: The COVID-19 pandemic has shed new light on inequities in healthcare access faced by immigrant and refugee communities. To address ongoing disparities, there is an urgent need for ecological approaches to better understand the barriers that hinder and resources that facilitate access to healthcare. This study investigates barriers to healthcare system access faced by Yazidi refugees in the Midwestern United States.

Methods: Informed by the Interpretative Phenomenological Approach, three focus group meetings with a community advisory board were conducted between September 2019 and January 2020. The nine-member focus group included social workers, healthcare providers, and members of …

How Demographic And Social Factors Correlate With The Perception Of Gluten And Gluten Sensitivity (Gs), Grace White

Scholar Week 2016 - present

Learning Objective: To determine which of the presented demographic and social factors correlate with GS or gluten misconceptions to discover potential contributors of GS.

Background: With an increase in GS cases, an exploration and understanding of how demographic and social factors such as gender, ethnicity, economic status, family/friend behavior, and social media correlate with GS and the perception of gluten was sought after.

Method: The researcher constructed a survey that was reviewed by 13 individuals for content, clarity, and internal consistency. The survey was sent out to the student body (2,658) at a small Midwestern university. The final …

Influence Of Acute Water Ingestion And Prolonged Standing On Raw Bioimpedance And Subsequent Body Fluid And Composition Estimates, Grant M. Tinsley, Matthew T. Stratton, Patrick S. Harty, Abegale D. Williams, Sarah J. White, Christian Rodriguez, Jacob R. Dellinger, Baylor A. Johnson, Robert W. Smith, Eric T. Trexler

Nutrition and Health Sciences -- Faculty Publications

This study evaluated the influence of acute water ingestion and maintaining an upright posture on raw bioimpedance and subsequent estimates of body fluids and composition. Twenty healthy adults participated in a randomized crossover study. In both conditions, an overnight food and fluid fast was followed by an initial multi-frequency bioimpedance assessment (InBody 770). Participants then ingested 11 mL/kg of water (water condition) or did not (control condition) during a 5-minute period. Thereafter, bioimpedance assessments were performed every 10 minutes for one hour with participants remaining upright throughout. Linear mixed effects models were used to examine the influence of condition and …

Encouraging Healthier Habits In Children, Krysta Hughes

IPS/BAS 495 Undergraduate Capstone Projects

Childhood obesity rates in America are the highest they've ever been. In this research we are focused on encouraging healthier habits in children. The method used was an observational, cross-sectional online survey of 5 children and 4 parents. All of the children and parents wanted to pick healthier behaviors after reading my book. A Qualtrics survey was used to record each surveyor's response. Further research on this topic should include researching how many children have began to implement healthier habits and measure if the rate of obesity in children has been affected through yearly health visits.

Influence Of Fertilizer Rate On Swollen Stem Formation (“Bulbing”) And Vitamin C Content In Different Kohlrabi Cultivars, Mark Iradukunda, Paul E. Read

Honors Theses, University of Nebraska-Lincoln

Kohlrabi (Brassica oleracea Gongylodes Group) is a vegetable crop found in the Brassicaceae, and it is rich in antioxidants such as vitamin C. Vitamin C helps in oxidative damage repair and strengthens the immune system, so exploring vitamin C sources may contribute to improving human health. The objective of this study was to determine the effect of different fertilizer rates on kohlrabi yield, in terms of the swollen stem and the vitamin C content, and if those effects are similar in different kohlrabi cultivars. In this greenhouse study, we fertilized four potted kohlrabi cultivars with a common water-soluble greenhouse fertilizer …

Ingredient Classification Using Food Ontology, Ricky Flores

UNO Student Research and Creative Activity Fair

A food label provides some of the most crucial information for a food product. The food label is a key resource for many health-conscious consumers for understanding ingredients. It is also vital for individuals to avoid food allergens or help patients follow dietary recommendations. While the food labels in the United States are regulated by the Food and Drug Administration (FDA) many labels contain additional information or statements that are not regulated. Moreover, the food label may be complex or contain terminology that the layperson may not understand. Evidence has indicated that consumers often find nutrition labels confusing, especially when …

Tissue Losses And Metabolic Adaptations Both Contribute To The Reduction In Resting Metabolic Rate Following Weight Loss, Alexandra Martin, Darius Fox, Chaise A. Murphy, Hande Hofmann, Karsten Koehler

Nutrition and Health Sciences -- Faculty Publications

OBJECTIVE: To characterize the contributions of the loss of energy-expending tissues and metabolic adaptations to the reduction in resting metabolic rate (RMR) following weight loss.

METHODS: A secondary analysis was conducted on data from the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy study. Changes in RMR, body composition, and metabolic hormones were examined over 12 months of calorie restriction in 109 individuals. The contribution of tissue losses to the decline in RMR was determined by weighing changes in the size of energy-expending tissues and organs (skeletal muscle, adipose tissue, bone, brain, inner organs, residual mass) …