Impact Of Different Partitioned Solvents On Chemical Composition And Bioavailability Of Sasa Quelpaertensis Nakai Leaf Extract,
2020
Taiwan Food and Drug Administration
Impact Of Different Partitioned Solvents On Chemical Composition And Bioavailability Of Sasa Quelpaertensis Nakai Leaf Extract, M. Nakamura, J.-H. Ra, Y. Jee, J.-S. Kim
Journal of Food and Drug Analysis
The leaves of Sasa quelpaertensis Nakai were extracted with 80% ethanol and further partitioned with n-hexane, chloroform, ethyl acetate, n-butanol, and aqueous fractions to evaluate the biological activity through assessment via various in vitro assays, including total phenol content; 1,1-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis-(3-ethylbenzothiazothiazoline-6-sulfornic acid (ABTS) radical scavenging; reducing power; α-glucosidase and tyrosinase inhibitory; and alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity assays. The highest activity was found in the ethyl acetate fraction for all assays and showed stronger DPPH radical scavenging, reducing power, and tyrosinase inhibitory activity than the positive controls (butylated hydroxytoluene, α-tocopherol, and arbutin, respectively). When compared …
Assessment Of Bacterial Quality Of Honey Produced In Tamale Metropolis (Ghana),
2020
Taiwan Food and Drug Administration
Assessment Of Bacterial Quality Of Honey Produced In Tamale Metropolis (Ghana), P. Adadi, A.K. Obeng
Journal of Food and Drug Analysis
The bacterial quality of honey from different production sites within Tamale metropolis, Ghana, was estimated using standard microbiological methods. Honey samples were bought from six different production sites within Tamale metropolis and labeled. Samples that were taken from location B recorded the least mean bacterial count of 6.0 × 104 colony forming units/mL with samples taken from location D showing the highest, 1.1 × 105 colony forming units/mL. However, samples from production sites E and F recorded no bacteria growth. Bacteria isolated included Escherichia coli, Staphylococcus spp., Shigella spp., Streptococcus spp., and Bacillus spp. The pH values of honey samples …
Simultaneous Separation Of Antihyperlipidemic Drugs By Green Ultrahigh-Performance Liquid Chromatography–Diode Array Detector Method: Improving The Health Of Liquid Chromatography,
2020
Taiwan Food and Drug Administration
Simultaneous Separation Of Antihyperlipidemic Drugs By Green Ultrahigh-Performance Liquid Chromatography–Diode Array Detector Method: Improving The Health Of Liquid Chromatography, M. Alghazi, F. Alanazi, K. Mohsin, N.A. Siddiqui, F. Shakeel, N. Haq
Journal of Food and Drug Analysis
Statins in combination with fibrates show beneficial effects on the lipoprotein profile of patients because they have positive complimentary effects on lipid profile. A new green ultrahigh-performance liquid chromatography–diode array detector method for simultaneous analysis of simvastatin (SMV) and fenofibrate (FNF) in standard form, marketed formulations, and self-emulsifying drug delivery system formulations was developed and validated in the present investigation. The method utilized C18 as stationary phase and a combination of methanol:water (8:2) as an eluent. It was found that selected eluent provided short run time (2.5 minutes), better peak symmetry and satisfactory values of other chromatographic parameters such as …
Rapid Investigation Of Α-Glucosidase Inhibitory Activity Of Phaleria Macrocarpa Extracts Using Ftir-Atr Based Fingerprinting,
2020
Taiwan Food and Drug Administration
Rapid Investigation Of Α-Glucosidase Inhibitory Activity Of Phaleria Macrocarpa Extracts Using Ftir-Atr Based Fingerprinting, S. Easmin, I.S.M. Zaidul, K. Ghafoor, S. Ferdosh, J. Jaffri, M.E. Ali, H. Mirhosseini, F.Y. Al-Juhaimi, V. Perumal, A. Khatib
Journal of Food and Drug Analysis
Phaleria macrocarpa, known as “Mahkota Dewa”, is a widely used medicinal plant in Malaysia. This study focused on the characterization of α-glucosidase inhibitory activity of P. macrocarpa extracts using Fourier transform infrared spectroscopy (FTIR)-based metabolomics. P. macrocarpa and its extracts contain thousands of compounds having synergistic effect. Generally, their variability exists, and there are many active components in meager amounts. Thus, the conventional measurement methods of a single component for the quality control are time consuming, laborious, expensive, and unreliable. It is of great interest to develop a rapid prediction method for herbal quality control to investigate the α-glucosidase inhibitory …
Voltammetric Sensor For Tartrazine Determination In Soft Drinks Using Poly (P-Aminobenzenesulfonic Acid)/Zinc Oxide Nanoparticles In Carbon Paste Electrode,
2020
Taiwan Food and Drug Administration
Voltammetric Sensor For Tartrazine Determination In Soft Drinks Using Poly (P-Aminobenzenesulfonic Acid)/Zinc Oxide Nanoparticles In Carbon Paste Electrode, G. Karim-Nezhad, Z. Khorablou, M. Zamani, Dorraji P. Seyed, M. Alamgholiloo
Journal of Food and Drug Analysis
Zinc oxide nanoparticles (ZnO NPs) and p-aminobenzenesulfonic acid (p-ABSA) were used to fabricate a modified electrode, as a highly sensitive and selective voltammetric sensor, for the determination of tartrazine. A fast and easy method for the fabrication of poly p-ABSA (Pp-ABSA)/ZnO NPs-carbon paste electrode (Pp-ABSA/ZnO NPs-CPE) by cyclic voltammetry was used. By combining the benefits of Pp-ABSA, ZnO NPs, and CPE, the resulted modified electrode exhibited outstanding electrocatalytic activity in terms of tartrazine oxidation by giving much higher peak currents than those obtained for the unmodified CPE and also other constructed electrodes. The effects of various experimental parameters on the …
Simultaneous Determination Of Ascorbic Acid And Caffeine In Commercial Soft Drinks Using Reversed-Phase Ultraperformance Liquid Chromatography,
2020
Taiwan Food and Drug Administration
Simultaneous Determination Of Ascorbic Acid And Caffeine In Commercial Soft Drinks Using Reversed-Phase Ultraperformance Liquid Chromatography, F. Turak, R. Güzel, E. Dinç
Journal of Food and Drug Analysis
A new reversed-phase ultraperformance liquid chromatography method with a photodiode array detector was developed for the quantification of ascorbic acid (AA) and caffeine (CAF) in 11 different commercial drinks consisting of one energy drink and 10 ice tea drinks. Separation of the analyzed AA and CAF with an internal standard, caffeic acid, was performed on a Waters BEH C18 column (100 mm × 2.1 mm, 1.7 μm i.d.), using a mobile phase consisting of acetonitrile and 0.2M H3PO4 (11:89, v/v) with a flow rate of 0.25 mL/min and an injection volume of 1.0 μL. Calibration graphs for AA and CAF …
Phytochemical Composition And Antibacterial Activity Of The Essential Oils From Different Parts Of Sea Buckthorn (Hippophae Rhamnoides L.),
2020
Taiwan Food and Drug Administration
Phytochemical Composition And Antibacterial Activity Of The Essential Oils From Different Parts Of Sea Buckthorn (Hippophae Rhamnoides L.), X.-F. Yue, X. Shang, Z.-J. Zhang, Y.-N. Zhang
Journal of Food and Drug Analysis
Essential oils from the seed, pulp, and leaf of sea buckthorn were obtained with hydrodistillation, and their phytochemical composition was analyzed through gas chromatography–mass spectrometry. Furthermore, the antibacterial activity of the oils was tested on five food-borne bacteria by spectrometry and evaluated in terms of minimum inhibitory concentration. The results indicate that the composition of all essential oils is dominated by free fatty acids, esters, and alkanes. Minimum inhibitory concentration values on each bacterium were obtained for oils from different parts. The oils from different parts exhibited nearly equal inhibitory effect on Staphylococcus aureus. The pulp oil was found to …
Relation Between Salt Tolerance And Biochemical Changes In Cumin (Cuminum Cyminum L.) Seeds,
2020
Taiwan Food and Drug Administration
Relation Between Salt Tolerance And Biochemical Changes In Cumin (Cuminum Cyminum L.) Seeds, Rebey I. Bettaieb, S. Bourgou, F.Z. Rahali, K. Msaada, R. Ksouri, B. Marzouk
Journal of Food and Drug Analysis
In this study, the effects of salinity on growth, fatty acid, essential oil, and phenolic composition of cumin (Cuminum cyminum L.) seeds as well as the antioxidant activities of their extracts were investigated. Plants were treated with different concentrations of NaCl treatment: 0, 50, 75, and 125 mmoL. Plant growth was significantly reduced with the severity of saline treatment. This also caused important reductions in the seed yield and yield components. Besides, NaCl treatments affected fatty acid composition. Petroselinic and linoleic acids proportions diminished consistently with the increase in NaCl concentration, whereas palmitic acid proportion increased. Furthermore, NaCl enhanced essential …
Study On The Interaction Of Bioactive Compound S-Allyl Cysteine From Garlic With Serum Albumin,
2020
Taiwan Food and Drug Administration
Study On The Interaction Of Bioactive Compound S-Allyl Cysteine From Garlic With Serum Albumin, Y.-E. Sun, W.-D. Wang
Journal of Food and Drug Analysis
Multispectroscopic techniques were used to investigate the interaction of S-allyl cysteine (SAC) from garlic with human serum albumin (HSA). UV–Vis absorption measurements prove the formation of the HSA–SAC complex. An analysis of fluorescence spectra revealed that in the presence of SAC, the quenching mechanism of HSA is considered static. The quenching rate constant Kq, KSV, and the binding constant KA were estimated. According to the Van't Hoff equation, the thermodynamic parameters enthalpy change (ΔH) and entropy change (ΔS) were calculated to be −1.00 × 105 J/mol and −255 J/mol/K, respectively. These indicate that hydrogen bonds and van der Waals forces …
Development Of Validated High-Performance Thin Layer Chromatography For Quantification Of Aristolochic Acid In Different Species Of The Aristolochiaceae Family,
2020
Taiwan Food and Drug Administration
Development Of Validated High-Performance Thin Layer Chromatography For Quantification Of Aristolochic Acid In Different Species Of The Aristolochiaceae Family, P. Agrawal, K. Laddha
Journal of Food and Drug Analysis
This study was undertaken to isolate and quantify aristolochic acid in Aristolochia indica stem and Apama siliquosa root. Aristolochic acid is an important biomarker component present in the Aristolochiaceae family. The isolation method involved simple solvent extraction, precipitation and further purification, using recrystallization. The structure of the compound was confirmed using infrared spectroscopy, mass spectrometry and nuclear magnetic resonance. A specific and rapid high-performance thin layer chromatography (HPTLC) method was developed for analysis of aristolochic acid. The method involved separation on the silica gel 60 F254 plates using the single solvent system of n-hexane: chloroform: methanol. The method showed good …
Phenolic Constituents Of Pulicaria Undulata (L.) C.A. Mey. Sub Sp. Undulata (Asteraceae): Antioxidant Protective Effects And Chemosystematic Significances,
2020
Taiwan Food and Drug Administration
Phenolic Constituents Of Pulicaria Undulata (L.) C.A. Mey. Sub Sp. Undulata (Asteraceae): Antioxidant Protective Effects And Chemosystematic Significances, S.R. Hussein, M.M. Marzouk, M.M. Soltan, E.K. Ahmed, M.M. Said, A.R. Hamed
Journal of Food and Drug Analysis
One new naturally isoflavone compound, 5,7,2′,3′,4′ penta hydroxyl isoflavone-4′-O-β-glucopyranoside (1) was isolated from the aqueous methanol extract (AME) of Pulicaria undulata subsp. undulata, together with seven known compounds: kaempferol (2), kaempferol 3-O-β-glucoside (3), quercetin (4), quercetin 3-O-β-glucoside (5), quercetin 3-O-β-galactoside (6), quercetin 3,7-di OCH3 (7), and caffeic acid (8). Their structures were established through chemical (acid hydrolysis) and spectral analysis (UV, NMR, and ESIM). The AME and some isolated compounds were evaluated as protective agents. Free radical scavenging using a microscaled 2,2-diphenyl-1-picrylhydrazyl assay was used to assess the direct antioxidant properties that were evaluated by the ability to protect murine …
Pharmacokinetic Interactions Of Herbal Medicines For The Treatment Of Chronic Hepatitis,
2020
Taiwan Food and Drug Administration
Pharmacokinetic Interactions Of Herbal Medicines For The Treatment Of Chronic Hepatitis, T.-P. Hsueh, W.-L. Lin, T.-H. Tsai
Journal of Food and Drug Analysis
Chronic liver disease is a serious global health problem, and an increasing number of patients are seeking alternative medicines or complementary treatment. Herbal medicines account for 16.8% of patients with chronic liver disease who use complementary and alternative therapies. A survey of the National Health Insurance Research Database in Taiwan reported that Long-Dan-Xie-Gan-Tang, Jia-Wei-Xia-Yao-San, and Xiao-Chai-Hu-Tang (Sho-saiko-to) were the most frequent formula prescriptions for chronic hepatitis used by traditional Chinese medicine physicians. Bioanalytical methods of herbal medicines for the treatment of chronic hepatitis were developed to investigate pharmacokinetics properties, but multicomponent herbal formulas have been seldom discussed. The pharmacokinetics of …
Albendazole Residues In Goat's Milk: Interferences In Microbial Inhibitor Tests Used To Detect Antibiotics In Milk,
2020
Taiwan Food and Drug Administration
Albendazole Residues In Goat's Milk: Interferences In Microbial Inhibitor Tests Used To Detect Antibiotics In Milk, T. Romero, R. Althaus, V.J. Moya, M.D.C. Beltrán, W. Reybroeck, M.P. Molina
Journal of Food and Drug Analysis
Albendazole (ABZ) residues in goat's milk and their effect on the response of microbial inhibitor tests used for screening antibiotics were evaluated. A total of 18 Murciano-Granadina goats were treated with ABZ and individually milked once a day over a 7-day period. ABZ quantification was performed by high performance liquid chromatography. The ABZ parent drug was not detected. The maximum concentration of its metabolites (ABZ sulfoxide, ABZ sulfone, and ABZ 2-aminosulfone) was reached on the 1st day post treatment (260.0 ± 70.1 μg/kg, 112.8 ± 28.7 μg/kg, 152.0 ± 23.6 μg/kg, respectively), decreasing to lower than the maximum residue limit …
Recent Advances In Oral Delivery Of Drugs And Bioactive Natural Products Using Solid Lipid Nanoparticles As The Carriers,
2020
Taiwan Food and Drug Administration
Recent Advances In Oral Delivery Of Drugs And Bioactive Natural Products Using Solid Lipid Nanoparticles As The Carriers, C.-H. Lin, C.-H. Chen, Z.-C. Lin, J.-Y. Fang
Journal of Food and Drug Analysis
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of many labile drugs. The GI epithelium also contributes to poor permeability for numerous drugs. Drugs with poor aqueous solubility have difficulty dissolving in the GI tract, resulting in low bioavailability. Nanomedicine provides an opportunity to improve the delivery efficiency of orally administered drugs. Solid lipid nanoparticles (SLNs) are categorized as a new generation of lipid nanoparticles consisting of a complete solid lipid matrix. SLNs used for oral administration offer several benefits over conventional formulations, including increased solubility, enhanced stability, improved epithelium permeability and bioavailability, prolonged half-life, …
Smog Induces Oxidative Stress And Microbiota Disruption,
2020
Taiwan Food and Drug Administration
Smog Induces Oxidative Stress And Microbiota Disruption, T.-Y. Wong
Journal of Food and Drug Analysis
Smog is created through the interactions between pollutants in the air, fog, and sunlight. Air pollutants, such as carbon monoxide, heavy metals, nitrogen oxides, ozone, sulfur dioxide, volatile organic vapors, and particulate matters, can induce oxidative stress in human directly or indirectly through the formation of reactive oxygen species. The outermost boundary of human skin and mucous layers are covered by a complex network of human-associated microbes. The relation between these microbial communities and their human host are mostly mutualistic. These microbes not only provide nutrients, vitamins, and protection against other pathogens, they also influence human's physical, immunological, nutritional, and …
Nanostructures: Current Uses And Future Applications In Food Science,
2020
Taiwan Food and Drug Administration
Nanostructures: Current Uses And Future Applications In Food Science, K. Pathakoti, M. Manubolu, H.-M. Hwang
Journal of Food and Drug Analysis
Recent developments in nanoscience and nanotechnology intend novel and innovative applications in the food sector, which is rather recent compared with their use in biomedical and pharmaceutical applications. Nanostructured materials are having applications in various sectors of the food science comprising nanosensors, new packaging materials, and encapsulated food components. Nanostructured systems in food include polymeric nanoparticles, liposomes, nanoemulsions, and microemulsions. These materials enhance solubility, improve bioavailability, facilitate controlled release, and protect bioactive components during manufacture and storage. This review highlights the applications of nanostructured materials for their antimicrobial activity and possible mechanism of action against bacteria, including reactive oxygen species, …
Corrigendum To “Hydrolysis Of Isoflavone In Black Soy Milk Using Cellulose Bead As Enzyme Immobilizer” [J Food Drug Anal (2016) 24 (788–795)] (S1021949816300485)(10.1016/J.Jfda.2016.03.007),
2020
Taiwan Food and Drug Administration
Corrigendum To “Hydrolysis Of Isoflavone In Black Soy Milk Using Cellulose Bead As Enzyme Immobilizer” [J Food Drug Anal (2016) 24 (788–795)] (S1021949816300485)(10.1016/J.Jfda.2016.03.007), K.-I. Chen, Y. Yao, H.-J. Chen, Y.-C. Lo, R.-C. Yu, K.-C. Cheng
Journal of Food and Drug Analysis
One affiliation of Kuan-Chen Cheng was missing. The affiliations should be increased “Department of Medical Research, China Medical University Hospital, China Medical University, 91, Hsueh-Shih Road, Taichung 40402, Taiwan”. © 2016
Corrigendum To “Assessment Of The Pharmacokinetics, Removal Rate Of Hemodialysis, And Safety Of Lactulose In Hemodialysis Patients” [J Food Drug Anal (2016) 24 (876–880)] (S1021949816300783)(10.1016/J.Jfda.2016.05.007),
2020
Taiwan Food and Drug Administration
Corrigendum To “Assessment Of The Pharmacokinetics, Removal Rate Of Hemodialysis, And Safety Of Lactulose In Hemodialysis Patients” [J Food Drug Anal (2016) 24 (876–880)] (S1021949816300783)(10.1016/J.Jfda.2016.05.007), C.-J. Lin, C.-F. Pan, S.-Y. Ju, H.-K. Tzeng, S.-W. Chen, J.-T. Syu, C.-J. Wu
Journal of Food and Drug Analysis
Two affiliations of Chih-Jen Wu were missing. The affiliations should be increased “Graduate Institute of Medical Sciences and Department of Pharmacology, College of Medicine, Taipei Medical University, Taipei, Taiwan” and “Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan”. © 2016
Classification And Regulatory Perspectives Of Dietary Fiber,
2020
Taiwan Food and Drug Administration
Classification And Regulatory Perspectives Of Dietary Fiber, F.-J. Dai, C.-F. Chau
Journal of Food and Drug Analysis
This review discusses the history and evolution of the state of dietary fiber (DF) with account of refinements in extraction methods and legal definitions subsequent to the launch of DF hypothesis. For a long time, defining and regulating DFs relied heavily on their chemical compositions and analytical methods. Although chemical compositions and analytical methods still play an important role in the definition of DF, physiological activity has also been taken into consideration. The precise definition of DF is still evolving, particularly whether oligosaccharides degrees of polymerization (DP) 3–9 should be considered as DF or not. Decades of scientific research have …
Bioactive Phytochemicals In Barley,
2020
Taiwan Food and Drug Administration
Bioactive Phytochemicals In Barley, E. Idehen, Y. Tang, S. Sang
Journal of Food and Drug Analysis
Epidemiological studies have consistently shown that regular consumption of whole grain barley reduces the risk of developing chronic diseases. The presence of barley fiber, especially β-glucan in whole grain barley, has been largely credited for these health benefits. However, it is now widely believed that the actions of the fiber component alone do not explain the observed health benefits associated with the consumption of whole grain barley. Whole grain barley also contains phytochemicals including phenolic acids, flavonoids, lignans, tocols, phytosterols, and folate. These phytochemicals exhibit strong antioxidant, antiproliferative, and cholesterol lowering abilities, which are potentially useful in lowering the risk …
