Orofacial Pain Commons^™

Gentle Beginnings: Innovative Use Of Melatonin And Triclofos Sodium For Uncooperative Children-An Invivo Study, Rohan Shrivastava, Sonal Gupta, Charu Aggarwal, Akil Prawin S.S

International Arab Journal of Dentistry

Objectives: To compare the pre- and post-use of oral melatonin and oral triclofos as oral sedative drugs on anxiety, sedation, and cognitive and psychomotor function to perform satisfactory dental treatment on uncooperative children.

Methods: A total number of 100 patients aged between 4 and 9 years who were scheduled for dental treatment were randomly divided into two groups, Group I and Group II, and administered melatonin and triclofos sodium, respectively, to determine changes in anxiety, cognitive, psychomotor, and sedation scores pre- and post-treatment. Data were analyzed using an unpaired/paired t-test, and P < 0.05 was contemplated as statistically significant.

Results: Post-treatment assessments revealed a significant reduction in …

Can Gingival Crevicular Fluid Help In Diagnosing Pulp Inflammation? A Systematic Review, Wael Kassamany, Roula Abiad

BAU Journal - Science and Technology

This review aims to find if there’s a positive correlation between biological markers detected in human gingival crevicular fluid and pulp inflammation.

An electronic search of three databases; PubMed, EBSCOhost and Google Scholar was conducted using the keywords “tooth or teeth or pulp” AND “gingival crevice fluid or gingival crevicular fluid” for English articles published between the year 1990 and 2026. Information regarding study design, patients age range and gender distribution, sampling method used, types of biomarkers studied, assay test used, and key findings of each article were extracted and analyzed.

Biomarkers studied were substance P “SP”, neurokinin A “NKA”, …

Does Adjunctive Low-Level Laser Therapy Provide Additional Benefit Following Temporomandibular Joint Arthrocentesis With Hyaluronic Acid? A Randomized Clinical Trial, Moataz Bahaa, Abdelrahman Fahmy Dr., Hesham Morsi, Mahmoud Elfaramawy

Dentistry

Purpose This study aimed to evaluate whether adjunctive low-level laser therapy (LLLT) provides additional clinical benefit over an optimized arthrocentesis protocol with hyaluronic acid in patients with ADDwoR. Materials and methods From December 2022 to December 2023, a single-blinded prospective randomized clinical trial was conducted at The British University in Egypt’s Department of Oral and Maxillofacial Surgery. The study involved 40 female participants diagnosed with Anterior Disc Displacement without Reduction (ADDwoR). Following TMJ arthrocentesis, subjects were assigned to one of two parallel cohorts: Group A received ten subsequent sessions of low-level laser therapy (LLLT), while Group B served as the …

Conservative Vs Invasive Interventions For Temporomandibular Disorders–An Executive Summary Of The Clinical Practice Guideline, Gary D. Klasser, Charles S. Greene

School of Dentistry Faculty Publications

This guideline is based on the International Association for Dental, Oral, and Craniofacial Research (IADR) list of keypoints for the diagnosis and management of TMDs. Clinical Question: Are conservative reversible therapies more effective for TMDs as compared to invasive and irreversible interventions?

Targeted Injection Therapies For Temporomandibular Joint Disorders: A Comparative Review Of Hyaluronic Acid And Botox Techniques, Timothy Alexander, Marissa Siegel, Noah Schnoor, Elizabeth A. Starns

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: This study aimed to evaluate the effectiveness of different injection therapies for temporomandibular joint disorders (TMD) and answer the research question: how do botulinum toxin (onabotulinumtoxinA, Botox) and hyaluronic acid (HA) injections affect symptoms of temporomandibular joint disorder (TMD)? Methods: An electronic search of three databases was performed using the search terms “Treatment of TMD or TMJ” and one of the following: 1) “Hyaluronic Acid Injection” or 2) “Intramuscular Botox Injection”. Based on studies done with human patients, the effects of both hyaluronic acid and Botox injections as treatments for TMD were observed and analyzed. Inclusion criteria were: full …

The Effects Of Mouthguard And Physiotherapy On Bruxism: An Emg And Posture Angle Analysis—A Pilot Clinical Study, Nathalie Yared, Pascal El Braidy, Romy Slaiby, Amine El Zoghby

International Arab Journal of Dentistry

Objectives: The purpose of this research was to determine whether a clinical trial to assess the impact of physiotherapy and mouthguards on bruxism was feasible. This included assessing participant recruitment, carrying out the interventions, and gathering data with appropriate techniques. The study focused on using posture angle analysis to evaluate changes in posture linked to bruxism and electromyography (EMG) to detect muscular activity. By exploring these elements, the study aimed to provide the groundwork for a more extensive, larger clinical trial.

Methods: Participants were recruited from the USJ dental clinics after their consultations. They were screened for bruxism using a …

Self-Medication Behavior Of Dental Students With Oral Ulceration Lesions: A Cross-Sectional Study In Yogyakarta, Indonesia, Fita Fathaya Iriana, Hendri Susanto, Rosa Amalia

Journal of Dentistry Indonesia

Objective: Self-medication refers to medication behavior for self-diagnosed symptoms. Oral ulcers are self-medicated lesions in the oral cavity. Dental students have different knowledge about oral cavity lesions and may self-medicate using drugs. This study aimed to determine the self-medication behavior of dental students for oral ulcers. Methods: This cross-sectional study was conducted on dental students in the Faculty of Dentistry from different batch years. Purposive sampling was used to select students with oral ulcer lesions in the last six months. A validated and reliable questionnaire was used to assess self-medication behavior. Data collection using the online form. Student behavior …

Lsu School Of Dentistry Launches New Residency In Orofacial Pain

New Orleans Dental Association News

Louisiana State University School of Dentistry announces a new two-year Advanced Education Program in Orofacial Pain, launching July 2025. The program provides interdisciplinary training, preparing specialists to manage complex oral and facial pain conditions through clinical care and academic instruction.

Defever Seminar: “Treating Tmd And Osa Patients: Relieve Your Headaches!”

Journal of the Macomb Dental Society

Presentation summary: The speakers focused on signs and symptoms of TMD that may be familiar and many that are commonly overlooked. This insight provides an opportunity to better identify and treat patients suffering from TMD. Various treatment methodologies were discussed with an emphasis on the concept of neuromuscular dentistry. Neuromuscular treatment of TMD involves identifying the mandibular position that corresponds to relaxed muscles of the anterior temporalis, masseters, and sternocleidomastoids. The benefit of the new TMJ position is confirmed using a custom orthotic and definitive treatment may involve long-term orthotic wear, dental reconstruction, or orthodontic treatment. There may be a …

Temporomandibular Joint Dysfunction (Tmjd), Jorge Pumachagua, Christopher Barnes, Elias Saliba

Discovery Day - Daytona Beach

The goal of this senior design project is to produce an alternative to the current market of dental guards available that non-invasively treat Temporomandibular joint dysfunction (TMJD). TMJD occurs when there is an anterior dislocation of the articular disk in reference to the condyle. The focus of the design is to prevent patients that have been rehabilitated by a specialist from regressing due to bruxism. Bruxism is a condition where teeth grind, gnash, or clench involuntarily at any time of the day, especially during sleep time. Bruxism engages the Masseter, Temporalis, Medial
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Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan

Student Works (2020-2029)

Oral squamous cell carcinoma (OSCC) is a malignancy that arises from the epithelial cells within the oral cavity. It accounts for approximately 355,000 new cases worldwide and is exceptionally prevalent in particular geographical areas such as Papua New Guinea, the Indian subcontinent and South-East Asian countries. Despite advances in surgical management and therapeutic approaches, the five-year survival rate of OSCC patients has not improved significantly over the past few decades. The mortality associated with OSCC is particularly high often due to late presentation, locoregional recurrence, distant metastases and the development of second primary tumours. A comprehensive understanding of the molecular …