Physical Sciences and Mathematics Commons^™

Advancing Data Usability, Activity Modeling, And Stability Optimization In Computational Enzyme Design, Spencer Gardiner

Theses and Dissertations

A grand challenge of computational biology is to computationally design, in a single pass, a protein sequence that catalyzes an arbitrary chemical reaction at a high rate under specified conditions [1]. This work details advances in three essential areas on the path to that goal: data quality, activity prediction and modeling, and stability optimization. The structure and implementation of the Allotrope Simple Model (a FAIR data format for many scientific instruments) was examined in [2], setting the stage for training deep learning models on high-quality experimental datasets from diverse sources. In [3], the limits of physics-based and deep learning tools …

What Makes A Modern Attention Implementation?, Brian H. Slonim

Master's Theses

Since the seminal assertion by Vaswani et al. in 2017 that “Attention Is All You Need,” transformer models have risen to ubiquity due to their ability to learn extremely complex patterns from sequence data, culminating in the unprecedented generative capabilities of large language models. These models’ strength lies in their scale: hundreds of millions (e.g., BERT-LARGE) to billions or trillions of learned parameters. Running inference with these models, let alone training them, would be intractable without significant innovations in the hardware and software that support them. This need has driven an enormous demand for GPU compute and associated software ecosystems, …

Principles Of Privacy And Security In Artificial Intelligence And Applications, Khang Tran

Dissertations

Modern artificial intelligence (AI) systems have transformed critical domains such as healthcare, software engineering, finance, and the legal system. Despite their broad impact, concerns about trustworthiness, especially regarding privacy and security, remain major obstacles to wider adoption. Addressing these concerns requires both a systematic understanding of the privacy and security risks inherent in AI systems and the development of principled foundations for trustworthy AI that safeguard client privacy and security. This goal is particularly challenging because of the complexity of modern large-scale AI systems, the trade-offs between privacy and model utility, and the need to simultaneously ensure other important properties …

Toward Learning-Based Reconstruction And Part Decomposition Of Man-Made 3d Geometry: Neural Implicit Representations And Scalable Supervision, Shen Fan

Dissertations

Digital three-dimensional (3D) models are central to engineering design, analysis, and manufacturing, but learning pipelines for man-made geometry often operate on sampled carriers that do not preserve all of the structure present in exact CAD representations. This dissertation studies learning-based reconstruction and part decomposition for structured man-made 3D geometry, from general object benchmarks to CAD-derived datasets, with a focus on neural implicit representations trained from signed-distance samples, point clouds, and tessellated meshes. The goal is to make these models more accurate, more part-aware, and more consistently supervised.

First, signed distance function (SDF) reconstruction with implicit neural representations is improved through …

Parameter Density Estimation For Cardiac Electrophysiology Models Using Data Consistent Deep Learning, Michael Luo

Dissertations

Mathematical models of biological rhythms and excitable systems can provide insights into mechanisms underlying cardiac electrical dynamics. However, estimating the parameters of these models from experimental observations is often difficult due to noise, heterogeneity, and unobserved variables. For example, in an electrocardiogram (ECG) recording, information about the electrical properties of different regions of the heart is compressed into a single voltage trace. Additionally, variability within these signals may contain important information about population heterogeneity, regional differences in electrophysiology, and time-dependent modulation.

This dissertation develops, explores, and evaluates methods that perform feature-based distributional inference for complex nonlinear dynamical systems. The objective …

Mri-Based Deep Learning Radiomics Model For Automated Classification Of Disc Degeneration In The Lumbar Spine, Shiv Patil, Om Gandhi, Mert Karabacak, Matthew Carr, Konstantinos Margetis

Student Papers, Posters & Projects

Disc degeneration in the lumbar spine is a major cause of low back pain (LBP). The accurate grading of disc degeneration on magnetic resonance imaging (MRI) is critical for clinical management and patient selection for spine surgery. This study aims to develop and evaluate machine learning (ML) models that combine features from deep learning (DL) and radiomics for the automated prediction of Pfirrmann grade (PG), a measure of disc degeneration, using multi-parametric lumbar spine MRI. Sagittal T1, T2, and T2 SPACE MRIs of 218 patients with LBP were acquired from the SPIDER dataset. For each intervertebral disc and available sequence, …

Hyperspectral Image Classification Using Novel 1-D And 2-D Deep Neural Networks, Özlem Polat, Zümray Dokur, Tamer Ölmez

Turkish Journal of Earth Sciences

Hyperspectral image (HSI) classification is of critical importance in many fields including agriculture, geology, environmental monitoring, and urban planning. In recent years, many researchers have utilized deep neural networks (DNNs), known for their high performance in the classification of HSIs. When 2-D/3-D convolutional neural networks are used in HSI classification, filters are applied using input patches typically larger than 11 × 11. This allows spectral and spatial features to be evaluated together. However, this combination creates several problems. Because HSIs have low spatial resolution, they often do not contain strong texture details. Furthermore, features with little relevance to classification make …

From Sparse To Precise: Modeling Beam Profiles Using Wavelet-Based Implicit Neural Network (Winn) For Linear Accelerator Commissioning And Quality Assurance, Maryam Ali Albuainin

Computer Science ETDs

Commissioning and routine quality assurance (QA) in radiotherapy require extensive measurements using bulky water tank systems, making the process time-consuming and costly. This research proposes an efficient framework for radiotherapy commissioning and QA by generating complete LINAC physics data from sparse measurements and developing a portable solid-water detector with embedded diodes for high-resolution dosimetry.

At the core of the framework is a Wavelet-based Implicit Neural Network (WINN) that reconstructs full measurement datasets from limited inputs while maintaining clinical accuracy. The model achieves gamma passing rates above 95% (1%/1 mm) and mean absolute errors below 0.5%, while reducing parameters by 99.46% …

A Descriptive Analysis Of Plant Leaf Disease Detection Using Machine Learning And Deep Learning Models: A Systematic Review, Arzoo Chamoli, Anuj Kumar

Turkish Journal of Electrical Engineering and Computer Sciences

Plant leaf disease detection (PLDD) is a growing active research area with burgeoning practical applications across various sectors such as agricultural monitoring, food security, and environmental conservation. Accurate segmentation and classification of plant leaf diseases remains a key challenge in the field of plant leaf disease prediction. The challenge demands automated methods for the plant disease identification because it needs to develop better crop management systems, which will boost agricultural production. In this article, we provide a systematic review of various machine learning (ML) and deep learning (DL) methods extensively used for PLDD. The review strategy follows a formal protocol, …

Durable, Distributed Llm Inference On Cots Devices, Brycen E. Dunn

Electronic Theses and Dissertations

The advancement of Large Language Models (LLMs) has fundamentally changed the nature of natural language processing. The substantial memory requirements of frontier models creates a significant barrier to entry, centralizing inference. This thesis presents the design and implementation of a distributed inference framework designed to democratize LLMs by leveraging commodity devices. The framework combines the resources of heterogeneous COTS devices into a unified compute pool, enabling the inference of models exceeding a single device's memory capacity. A novel Task Partitioning Engine (TPE) analyzes model architectures, profiles node capabilities, and supports pipeline and expert parallelism strategies. The primary contribution is a …

Multimodal Aerial Image-Based Ground Object Detection And Classification Using Yolo, Erik Nielsen

All Theses

Object detection in unmanned aerial vehicles (UAVs) present a unique challenge due to small object sizes, varying viewpoints, and changing environmental conditions. These challenges are exacerbated when operating during daytime and nighttime scenarios where illumination differences can heavily impact detection performance. This work is motivated by military object detection applications where the ability to reliably identify small objects such as landmines or unexploded ordnance from aerial imagery presents a critical safety need and a significant technical challenge. In this paper, we investigate object detection using both visible (RGB) and infrared (IR) imagery to improve robustness and reliability across diverse operating …

A Deep Learning-Based Approach For Bot Detection In Trending Hashtags On X, Mehboob Hussain, Muhammad Rizwan Rashid Rana, Muhammad Imran, Muhammad Shoaib, Muhammad Hasaan Mujtaba

Makara Journal of Technology

The widespread presence of bots on social media platforms, such as X (formerly Twitter), poses a significant threat to the integrity of online information by facilitating the dissemination of misinformation and manipulating public discourse. This study proposes a robust deep learning-based framework, DeepBot, to detect bot participation in trending hashtags and discussions on X. The approach uses a dataset sourced from Kaggle, comprising user profile metadata, including follower count, tweet frequency, account verification status, and engagement metrics. The data were subjected to comprehensive preprocessing, including noise removal, part-of-speech (POS) tagging, and word embedding using the pre-trained GloVe model. RoBERTa is …

Modelling Method Of Unmanned Vehicle Dynamics Based On Neural Network, Jun Wang, Min Liu, Xiaochuan Zhang, Yishan Ding, Juhui Feng, Ye Zhuang

Journal of System Simulation

Abstract: To address the challenges of high data acquisition costs of test data on dynamic characteristics between tires and soft terrain and low speed of numerical calculation for unmanned vehicles in complex terrestrial environments, a modeling method of unmanned vehicle dynamics based on a neural network was proposed. Tire-terrain contact dynamics models were built by using discrete element method (DEM) simulations for tire-terrain contact and experimental data, thereby creating a dataset of tire contact forces for various tire materials in terrestrial environments. The neural network was applied to regressively learn the dataset, and a nonlinear neural network tire model was …

Comparative Analysis Of Mlp And Cnn Models For Cardiac Arrhythmia Classification, Veltman Okey-Ejowhor, Vahid Emamian

Posters - 2026

Electrocardiogram (ECG) is a record of the electric activity of the heart over time. ECG analysis plays a pivotal role in diagnosing critical heart conditions. Significant developments have been made in the realm of deep learning and applied artificial intelligence. These deep learning models have been utilized heavily because of their ability to analyze deep morphological features of each signal. The model architecture used in this study is a convolutional neural network (CNN) combined with a multi-layered perceptron (MLP). The MLP acts as an input filter that classifies normal heartbeat signals from abnormal. The CNN is the second filter in …

Deep Learning Frameworks For Biological Data Integration And Generation, Alexa Beachum

Statistical Science Theses and Dissertations

Data integration represents a key area of research for analyzing the rapidly growing volume of high-dimensional biological data across sources, stages, and modalities. To model and understand these complex, often non-linear relationships, deep learning has become an increasingly powerful tool. Here, we present two novel deep learning frameworks that address distinct but complementary integration challenges. The first framework aligns single-cell omics data across temporal stages, and the second bridges imaging and omics modalities to generate patient-level molecular profiles.

In Chapter 1, we briefly summarize existing approaches---both statistical and deep learning-based---for single-cell omics data integration and discuss their limitations for handling …

Deep Learning Based Approaches For Low Cost Defense Detection, Adele J. Noel-Rickert

All NMU Master's Theses

Pulmonary fibrosis is a progressive interstitial lung disease characterized by the accumulation of fibrotic tissue within the lungs, leading to impaired respiratory function and reduced quality of life. Early detection is important for disease management; however, accurate diagnosis often relies on high-resolution computed tomography (CT), which may not be accessible in all clinical settings. Chest radiography provides a lower-cost and widely available imaging modality, but interpretation of chest X-rays for fibrotic disease can be challenging due to subtle radiographic patterns and overlapping anatomical structures. This thesis investigates the use of multimodal deep learning techniques to assist in pul- monary fibrosis …

Multi-Modal Tensor Fusion For Alzheimer’S Disease Recognition, Mason Li, Tiffany Le, Jiajing Huang, Yuxin Wen

Engineering Faculty Articles and Research

Accurate and early diagnosis of Alzheimer’s disease (AD) is critical for effective intervention, disease monitoring, and patient care. Traditional diagnostic approaches rely on a single modality, such as clinical assessments, neuroimaging, or genetic markers, which may fail to capture the complex, multifaceted nature of AD. Multimodal learning has therefore been explored to integrate complementary information across data sources. However, conventional fusion strategies, including early feature concatenation and late decision-level fusion, often model modalities independently and fail to capture high-order cross-modal interactions. To address these limitations, we propose a multimodal tensor fusion network (MTFN) that integrates heterogeneous data sources, including visual …

Large-Scale File Fragment Classification Via Multi-View Learning, Samuel Hildebrand

LSU Master's Theses

File reassembly is one of the most fundamental tasks in digital forensics, enabling recovery of data from potentially damaged storage media even when file system metadata is unavailable. This thesis reviews more than two decades of work in the realm of file carving, with a particular focus on fragmented file carving, which remains a focus of research, and file fragment classification, a principal component of fragmented file carving. This thesis serves a literature review of both file carving and fragmented file carving, surveys the massive amounts of data needed for the task of fragment classification and the datasets that serve …

Deep Learning Based Routing And Clustering Approaches For Energy Optimization In 5g Wireless Sensor Networks: A Review, Ghufraan Ali Mohammad Jawad, Ahmed M. Al-Salih

Journal of Intelligent Informatics, Networking, and Cybersecurity

Next-generation Wireless Sensor Networks (WSNs), including 5G and Beyond-5G networks, have made significant progress. However, their development requires re-evaluating intelligent communication approaches to meet the growing demands for higher data transmission rates, more efficient spectral utilization, and reduced energy consumption. Scalability issues related to energy efficiency remain a critical concern for WSNs, which remain integral to the digital revolution. This paper investigates the role of Deep Learning (DL) methods in improving energy efficiency for routing and clustering in 5G WSNs. It is pertinent to note that Deep Q-Networks (DQNs) and their variants have significantly enhanced Cluster Heads (CHs) selection schemes …

Simulation And Multi-Perspective Recognition Algorithm For Typical Trajectory Shapes, Xuejian Feng, Han Ding, Yiqi Tong, Chaoying Huo, Yanjin Zhang

Journal of System Simulation

Abstract: Current trajectory simulation methods inadequately address geometric shape features and kinematic properties of the target trajectory. To bridge this gap, a target trajectory shape simulation algorithm based on kinematic laws was proposed. The polar coordinate equations and curvature equations of multiple trajectories were integrated. The aircraft state parameters were solved by combining kinematic equations. Angular Gaussian noise was introduced to enhance trajectory diversity and authenticity. Additionally, a multi-perspective trajectory shape recognition algorithm was designed, which could effectively integrate image and sequential multi-modal features by adopting a multilayer perceptron, enabling precise trajectory shape recognition. Experimental results demonstrate that the proposed …

Research On Visual Place Recognition Algorithms For Complex Urban Environments, Peijin Liu, Minxin Zhang, Lin He, Yige Sun, Tingqi Su

Journal of System Simulation

Abstract: Dynamic factors such as traffic flow and crowd density in complex urban environments reduce the accuracy of visual place recognition (VPR) algorithms. To solve these problems, a semantic-guided visual place recognition (SG-VPR) algorithm was proposed. A semantic-guided feature suppression module was designed. A semantic-guided module and feature suppression layer were constructed to reduce the dynamic object interference and more accurately extract the key static features. An adaptive triplet margin loss function (ATML) was proposed by improving the traditional triplet margin loss. The margins were adaptively adjusted according to the sample distribution, solving the problem of suboptimal solution convergence …

A Unified Non-Visual Explainable Ai Framework For Neonatal Pain Assessment, Md Imran Hossain

USF Tampa Graduate Theses and Dissertations

With the power of parallel processing, large datasets, and fast computational resources,deep neural networks (DNNs) have outperformed highly trained and experienced human experts in medical applications. However, the large global community of healthcare professionals, many of whom routinely face potentially life-or-death outcomes with complex medicolegal consequences, have yet to embrace this powerful technology. The major problem is that most current AI solutions function as a metaphorical black-box positioned between input data and output decisions without a rigorous explanation for their internal processes. With the goal of enhancing trust and improving acceptance of artificial intelligence– (AI) based technology in clinical medicine, …

Super-Resolution Remote Sensing Datasets For Application To Caral–Supe Archeological Sites Employing Sar And Dems, Jungrack Kim, Ramesh P. Singh

Mathematics, Physics, and Computer Science Faculty Articles and Research

Publicly accessible spaceborne remote sensing datasets often lack the spatial resolution required to reliably distinguish archeological features from their surrounding geomorphological contexts. In this study, we assess the potential of super-resolution (SR) products derived from multiple public-domain remote sensing datasets for a systematic archeological survey in the Caral–Supe region. We focus on Synthetic Aperture Radar (SAR) and topographic datasets—including Sentinel-1, Advanced Land Observing Satellite (ALOS) Phased Array L-band Synthetic Aperture Radar (PALSAR), and Digital Elevation Models (DEMs)—because of their capacity to detect subtle surface expressions and shallow subsurface structures obscured by vegetation or sediment cover. Using state-of-the-art deep learning algorithms, …

Deep Learning Approaches For Anti-Money Laundering On Mobile Transactions: Review, Framework, And Directions, Jiani Fan, Lwin Khin Shar, Ruichen Zhang, Ziyao Liu, Wenzhuo Yang, Dusit Niyato, Kwok-Yan Lam

Research Collection School Of Computing and Information Systems

Money laundering is a financial crime that obscures the origin of illicit funds, necessitating the development and enforcement of anti-money laundering (AML) policies by governments and organizations. The proliferation of mobile payment platforms and smart IoT devices has significantly complicated AML investigations. As payment networks become more interconnected, there is an increasing need for efficient real-time detection to process large volumes of transaction data on heterogeneous payment systems by different operators such as digital currencies, cryptocurrencies, and account-based payments. Most of these mobile payment networks are supported by connected devices, many of which are considered loT devices in the FinTech …

Hybrid Deep Learning For Anti-Money Laundering: Unsupervised Detection Of Emerging Schemes Via Feature Fusion And Explainable Artificial Intelligence, Cosmas Ochieng Kungu, Kennedy Senagi, Evans Omondi

All Peer-Reviewed Publications

Traditional rule-based anti-money laundering (AML) transaction monitoring systems suffer from high false-positive rates and rigidity in detecting complex emerging risk. This limitation has prompted changes to the Financial Action Task Force (FATF) recommendation 16, mandating the use of advanced systems for detecting money laundering schemes in cross-border payments. This study developed a hybrid framework integrating VAE-learned behavioural latent factors, GNN-captured relational network signals, and rule-based heuristics for enhanced anomaly detection. The model was evaluated on 54,258 real-world cross-border transaction records from an East African commercial bank. The One-Class SVM, optimised via a rigorous grid search proved superior compared to Isolation …

Transformer-Driven Intelligent Prediction For The Time-Series Features Of Mine Pressure In Fully Mechanized Mining Face, Du Feng, Chen Bo, Wang Wenqiang, Pu Hai, Du Xueming, Li Guodong, Qiao Rui, Li Xinlei, Xu Jie, Cao Yu

Coal Geology & Exploration

Objective Mine pressure prediction represents an important means for early warning and management of disasters in coal seam roofs, serving as the prerequisite and foundation for safe production in intelligent mines. However, the complex and variable conditions of fully mechanized mining face lead to significant variations in the distribution of support pressure data acquired using electro-hydraulic control systems, complicating mine pressure prediction. Methods This study developed a Transformer-based mine pressure prediction model. Specifically, missing mine pressure data were filled using linear interpolation, and the data structure of mine pressure was adjusted using a sliding window algorithm. Based on the time-series …

A Conceptual Framework On Development Of Sign Language Chatbot For E-Commerce, Salma Jahan Nisha, Nabhan Salih, Wan-Noorshahida Mohd-Isa

Journal of Informatics and Web Engineering

This study proposes and validates a conceptual framework using a sign language (SL) chatbot in the e-commerce domain to improve accessibility. Currently, the use of SL is a less-explored area in online platforms. It is difficult for any communication-challenged person to interact online for buying products and services, using a chatbot, particularly for people using SL. The objective of this study is to introduce a novel hybrid architecture using SL Recognition with a conversational-based chatbot agent via a custom Application Programming Interface (API) in e-commerce platforms. Our work proposes a combined hybrid chatbot framework model using Convolutional Neural Network (CNN) …

An Ai Approach To Lunar Phase Detection: Enhancing The Identification Of The New Crescent With Astronomical Data Integration, Murad Al-Rajab, Samia Loucif, Raed Abu Zitar, Mubarak Gwaza Abdu-Aguye

All Works

Introduction: The observation of the lunar crescent is significant in astronomy, cultural traditions, and religious lunar calendar determinations. However, earth-based imaging that captures all lunar phases, particularly the new crescent across multiple months, remains limited. This study explores the feasibility of using artificial intelligence (AI) techniques to detect and analyze the birth of the new lunar crescent using space-borne imagery from NASA’s Lunar Reconnaissance Orbiter (LRO), spanning over 13 years. Methods: This study evaluates both deep learning and traditional machine learning approaches for new crescent detection. Convolutional Neural Networks (CNN), Random Forests (RF), and Support Vector Machines (SVM) were applied …

Obstructive Sleep Apnea Prediction: A Comprehensive Review And Comparative Study, Thi Khanh Chi Huynh, Amonae Dabbs-Brown, Anna Jurek-Loughrey, James Mulhall, Tuan Dung Pham, Ngoc Phu Doan, Viet Hung Tran, Zichi Zhang, Xuan Hoang Nguyen, Yimeng An, Peixin Li, Phi Hung Nguyen, Thi Linh Hoang, Xinming Shi, Hans Vandierendonck, Sebastien Bailly, Jean-Louis Pépin, Thai Son Mai

Research Collection School Of Computing and Information Systems

Obstructive Sleep Apnea (OSA) is a highly prevalent sleep disorder linked to considerable public health burdens and comorbidities. However, its heterogeneous presentation and the limited accessibility of traditional diagnostic tools such as polysomnography (PSG) lead to widespread underdiagnosis. As a result, artificial intelligence (AI) approaches, including machine learning (ML) and deep learning (DL) models, have attracted attention as an alternative pathway to detection. This paper first provides a comprehensive review of AI-driven OSA diagnosis, covering different diagnosis problems, input-data types, data biases, pre-processing techniques, and model performance. We then leverage the largest clinical dataset used in OSA prediction to date, …

Machine Learning In Peak Demand Forecasting: Foundations, Trends, And Insights, Shuang Dai, Fanlin Meng, Hongsheng Dai, Qian Wang, Xizhong Chen, Wenlei Bai, Peizhi Shi, Richard Allmendinger, Yuchen Zhang, Jian Liu

Electrical and Computer Engineering Faculty Research & Creative Works

Peak demand forecasting involves predicting the maximum electricity demand within a specific period, which plays a key role in maintaining the efficiency and stability of power systems. The rapid evolution of power systems, driven by advanced metering infrastructure, local energy applications such as electric vehicles, and the increasing adoption of intermittent renewable energy, has introduced greater randomness and reduced predictability in peak demand. Given the pressing need to address more diverse implementation requirements across different contexts, accurate and reliable peak demand forecasting has become increasingly important. To the best of our knowledge, this study is the first to provide a …