Physical Sciences and Mathematics Commons^™

Porous Polymer Coatings As Substrates For The Formation Of High-Fidelity Micropatterns By Quill-Like Pens, Michael Hirtz, Marcus Lyon, Wenqian Feng, Andrea E. Holmes, Harald Fuchs, Pavel A. Levkin

Department of Chemistry: Faculty Publications

We explored the potentials of microarray printing using quill-like microcantilevers onto solid supports that are typically used in microspot printing, including paper, polymeric nitrocellulose and nylon membranes. We compared these membranes with a novel porous poly(2-hydroxyethyl methacrylate-co-ethylene dimethacrylate) support (HEMA) with narrow pore size distribution in the 150 nm range, which demonstrated advantages in pattern definition, spot homogeneity, and consistent spot delivery of different dyes (phloxine B and bromophenol blue) with diameters of several micrometres. The bromophenol blue arrays on HEMA support were used to detect the presence of bovine serum albumin (BSA). In the presence of BSA, …

Single Transcriptional And Translational Preq1 Riboswitches Adopt Similar Pre-Folded Ensembles That Follow Distinct Folding Pathways Into The Same Ligand-Bound Structure, Krishna C. Suddala, Arlie J. Rinaldi, Jun Feng, Anthony M. Mustoe, Catherine D. Eichhorn, Joseph A. Liberman, Joseph E. Wedekind, Hashim M. Al-Hashimi, Charles L. Brooks Iii, Nils G. Walter

Department of Chemistry: Faculty Publications

Riboswitches are structural elements in the 50 untranslated regions of many bacterial messenger RNAs that regulate gene expression in response to changing metabolite concentrations by inhibition of either transcription or translation initiation. The preQ₁ (7-aminomethyl-7-deazaguanine) riboswitch family comprises some of the smallest metabolite sensing RNAs found in nature. Once ligand-bound, the transcriptional Bacillus subtilis and translational Thermoanaerobacter tengcongensis preQ₁ riboswitch aptamers are structurally similar RNA pseudoknots; yet, prior structural studies have characterized their ligand-free conformations as largely unfolded and folded, respectively. In contrast, through single molecule observation, we now show that, at nearphysiological Mg²⁺ concentration and pH, …

Layer-Bounding Surfaces In Stalagmites As Keys To Better Paleoclimatological Histories And Chronologies, Loren Bruce Railsback, Pete D. Akers, Lixin Wang, Genevieve A. Holdridge, Ny Riavo Voarintsoa

International Journal of Speleology

Petrographic recognition of layer-bounding surfaces in stalagmites offers an important tool in constructing paleoclimate records. Previous petrographic efforts have examined thickness of layers (a possible proxy for annual rainfall) and alternation of layers in couplets (a possible indicator of seasonality). Layer-bounding surfaces, in contrast, delimit series of layers and represent periods of non-deposition, either because of exceptionally wet or exceptionally dry conditions.

Two types of layer-bounding surfaces can be recognized according to explicitly defined petrographic criteria. Type E layer-bounding surfaces are surfaces at which layers have been truncated or eroded at the crest of a stalagmite. Keys to their recognition …

Quantum Cheshire Cats, Yakir Aharonov, Sandu Popescu, Daniel Rohrlich, Paul Skrzypczyk

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper we present a quantum Cheshire Cat. In a pre- and post-selected experiment we find the Cat in one place, and its grin in another. The Cat is a photon, while the grin is its circular polarization.

Inter- And Intra-Annual Variability Of Vegetation In The Northern Hemisphere And Its Association With Precursory Meteorological Factors, Boksoon Myoung, Yong-Sang Choi, Seungbum Hong, Seon Ki Park

Mathematics, Physics, and Computer Science Faculty Articles and Research

Determination of phenological variation is one of the most critical challenges in dynamic vegetation modeling, given the lack of a strong theoretical framework. Previous studies generally focused on the timing of a phenological event (e.g., bud-burst or onset of growing season) and its atmospheric prompts, but not on the interactive variations across phenological stages. This study, therefore, investigated the inter- and intra-annual variability existing in all the phenological stages and the relations of the variability with four meteorological variables (surface temperature (Ts), shortwave radiation (SW ), vapor pressure deficit (VPD), and precipitation (PRCP)) using a 25-year (1982-2006) dataset of leaf …

Relation Algebras As Expanded Fl-Algebras, Nikolaos Galatos, Peter Jipsen

Mathematics, Physics, and Computer Science Faculty Articles and Research

This paper studies generalizations of relation algebras to residuated lattices with a unary De Morgan operation. Several new examples of such algebras are presented, and it is shown that many basic results on relation algebras hold in this wider setting. The variety qRA of quasi relation algebras is defined and shown to be a conservative expansion of involutive FL-algebras. Our main result is that equations in qRA and several of its subvarieties can be decided by a Gentzen system, and that these varieties are generated by their finite members.

Pontryagin De Branges-Rovnyak Spaces Of Slice Hyperholomorphic Functions, Daniel Alpay, Fabrizio Colombo, Irene Sabadini

Mathematics, Physics, and Computer Science Faculty Articles and Research

We study reproducing kernel Hilbert and Pontryagin spaces of slice hyperholomorphic functions which are analogs of the Hilbert spaces of analytic functions introduced by de Branges and Rovnyak. In the first part of the paper we focus on the case of Hilbert spaces, and introduce in particular a version of the Hardy space. Then we define Blaschke factors and Blaschke products and we consider an interpolation problem. In the second part of the paper we turn to the case of Pontryagin spaces. We first prove some results from the theory of Pontryagin spaces in the quaternionic setting and, in particular, …

Maximally Epistemic Interpretations Of The Quantum State And Contextuality, Matthew S. Leifer, O. J. E. Maroney

Mathematics, Physics, and Computer Science Faculty Articles and Research

We examine the relationship between quantum contextuality (in both the standard Kochen-Specker sense and in the generalized sense proposed by Spekkens) and models of quantum theory in which the quantum state is maximally epistemic.We find that preparation noncontextual models must be maximally epistemic, and these in turn must be Kochen-Specker noncontextual. This implies that the Kochen-Specker theorem is sufficient to establish both the impossibility of maximally epistemic models and the impossibility of preparation noncontextual models. The implication from preparation noncontextual to maximally epistemic then also yields a proof of Bell’s theorem from an Einstein-Podolsky-Rosen-like argument.

Photometric Observations Of 782 Montefiore, 3842 Harlansmith, 5542 Moffatt, 6720 Gifu, And (19979) 1989 Vj, Xianming Han, Bin Li, Haibin Zhao, Wenjuan Liu, Luming Sun, Jingjing Shi, Shan Gao, Shufen Wang, Xiang Pan, Peng Jiang, Hongyan Zhou

Scholarship and Professional Work - LAS

Five solar system minor planets were measured photometrically between 2012 October and December using the SARA (Southeastern Association for Research in Astronomy) telescopes located in Kitt Peak National Observatory in USA and Cerro Tololo Inter-American Observatory in Chile. The following synodic periods were found: 782 Montefiore P = 4.0728 ± 0.0006 h; 3842 Harlansmith, P = 2.7938 ± 0.0005 h; 5542 Moffatt P = 5.187 ± 0.001 h; 6720 Gifu, P = 4.231 ± 0.001 h; and (19979) 1989 VJ, P = 7.568 ± 0.005 h.

Cell Speed Is Independent Of Force In A Mathematical Model Of Amoeboidal Cell Motion With Random Switching Terms., J. C. Dallon, Emily J. Evans, Christopher Grant, William V. Smith

Faculty Publications

In this paper the motion of a single cell is modeled as a nucleus and multiple integrin based adhesion sites. Numerical simulations and analysis of the model indicate that when the stochastic nature of the adhesion sites is a memoryless and force independent random process, the cell speed is independent of the force these adhesion sites exert on the cell. Furthermore, understanding the dynamics of the attachment and detachment of the adhesion sites is key to predicting cell speed. We introduce a differential equation describing the cell motion and then introduce a conjecture about the expected drift of the cell, …

Cancer Quasispecies And Stem-Like Adaptive Aneuploidy, Domenico Napoletani, M. Signore, Daniele C. Struppa

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper we develop a theoretical frame to understand self-regulation of aneuploidy rate in cancer and stem cells. This is accomplished building upon quasispecies theory, by leaving its formal mathematical structure intact, but by drastically changing the meaning of its objects. In particular, we propose a novel definition of chromosomal master sequence, as a sequence of physically distinct whole or fragmented chromosomes, whose length is taken to be the sum of the copy numbers of each whole or fragmented chromosome. This fundamental change in the functional objects of quasispecies theory allows us to show that previously measured aneuploidy rates …

Using Genetic Algorithms To Find Cellular Automata Rule Sets Capable Of Generating Maze-Like Game Level Layouts, Andrew Pech

Theses : Honours

The video game industry has grown substantially over the last decade and the quality of video games has also been advancing rapidly. In recent years, video games have been advancing to a point that the increased time required to manually create their content is making this process too costly. This has made procedural content generation a desirable option for game developers due to its speed of generating content, and the variety of content that a single PCG method can produced.

The main purpose of this dissertation is to detail a new approach to procedurally generate video game level layouts, and …

Synthesis Of Orthogonally Protected Azalanthionines (Lanazanines) By Sequential Ring-Opening Of N-Substituted Aziridine 2-Carboxylates, Keith O'Brien, Keith Ó Proinsias, Fintan Kelleher

Articles

Orthogonally protected azalanthionines (lanazanines, 4-azadiaminopimelic acids or b-aminoalaninoalanines) have been synthesised in good yields by the ring-opening of N-protected aziridine 2-carboxylates with suitably protected diaminopropanoic acids (DAPs). The required DAPs were also synthesised by ring-opening of N-protected aziridine 2-carboxylates with para-methoxybenzylamine.

Raman Micro Spectroscopy Study Of The Interaction Of Vincristine With A549 Cells Supported By Expression Analysis Of Bcl-2 Protein, Haq Nawaz, Amaya Garcia, Aidan Meade, Fiona Lyng, Hugh Byrne

Articles

Understanding the interaction of anticancer drugs with model cell lines is important to elucidate the mode of action of these drugs as well as to develop cost effective and rapid screening methods. Raman spectroscopy has been demonstrated to be a valuable technique for high throughput, noninvasive analysis. The interaction of vincristine with a human lung adenocarcinoma cell line (A549)was investigated using Raman micro spectroscopy. The results were correlated with parallel measurements from the MTT cytotoxicity assay, which yielded an IC₅₀ value of 0.10 ± 0.03 μM. The Raman spectral data acquired from vincristine treated A549 cells was analysed to …

Table Of Contents

International Journal of Speleology

No abstract provided.

Chemical Analysis Of Ophthalmic Solutions, Pagagiotis Tavlarakis

Seton Hall University Dissertations and Theses (ETDs)

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Simple, Complete, And Novel Quantitative Model Of Holography For Students Of Science And Science Education, Dale Olson

Faculty Work

A Moiré graphical method for predicting the directions of all permitted image waves for thin and volume holograms is described. This method has been developed in connection with a holography centred optics course for students in science, technology and science education that has evolved over several decades. A somewhat unique view of the holographic process underlies this novel method of predicting the behaviour of diffraction gratings.

Effects Of Flooding On The Flora And Fauna Of A Reconstructed Tallgrass Prairie, Andrew J. Ridgway, Mark C. Myers, Benjamin Hoksch

Undergraduate Student Work

Prairie restoration for the purpose of biofuel production has the potential to be much more beneficial than using corn-based ethanol. These benefits include less damage to soil from fertilizers or pesticides, less management and greater suitability for native fauna. The current study of this restoration consists of surveying vegetation characteristics on four different soil types seeded with four different mixes, as well as observing bird and butterfly use of the restoration. In the fourth year of management of this particular prairie restoration a great deal of flooding occurred. The frequency and intensity of the flooding had a great affect on …

Birds And Butterflies Respond To Soil-Induced Habitat Heterogeneity In Experimental Plantings Of Native Tallgrass Prairie Species In Iowa, Usa, Benjamin J. Hoksch, Mark C. Myers, James T. Mason, Jarrett D. Pfrimmer, Andrew J. Ridgway

Undergraduate Student Work

We studied interrelationships between prairie plant establishment, habitat heterogeneity, and bird and butterfly biodiversity in an experimental prairie reconstruction in Iowa, USA. We seeded 48 research plots on three soil types with one of four treatments containing one, five, 16, or 32 species. During early establishment, neither bird nor butterfly abundance, species richness, or community diversity varied among the three soil types; however, there were significant treatment × soil type interactions when comparing bird and butterfly community composition among plots. Our results demonstrate that plots established with identical seed mixes and management practices developed variable habitat characteristics due to variation …

On The Difference In Quality Between Current Heuristic And Optimal Solutions To The Protein Structure Alignment Problem, Mauricio Arriagada, Aleksandar Poleksic

Faculty Work

The importance of pairwise protein structural comparison in biomedical research is fueling the search for algorithms capable of finding more accurate structural match of two input proteins in a timely manner. In recent years, we have witnessed rapid advances in the development of methods for approximate and optimal solutions to the protein structure matching problem. Albeit slow, these methods can be extremely useful in assessing the accuracy of more efficient, heuristic algorithms. We utilize a recently developed approximation algorithm for protein structure matching to demonstrate that a deep search of the protein superposition space leads to increased alignment accuracy with …

Analysis Of Mathematical Descriptions Of Gravitational Microlensing, Sarah Michelle Pearce

Honors Program Theses

This thesis will provide an analysis of some aspects of gravitational microlensing and the quantitative descriptions used to model the astrophysical systems involved. One aspect of the mathematical description of micro lensing events that is investigated in this thesis is the evolution of micro lensing equations from the formalism of general relativity. The derivation of these equations from those governing general relativity and the bending of light rays in geometric optics is explicitly determined. The relationship between the equations used to model events and the light curves produced is investigated. The effect of degeneracies in the mathematical equations used to …

Developing Crochet Patterns For Surfaces Of Non-Constant Curvature, Katherine Lea Pearce

Honors Program Theses

The purpose of this project is to develop an algorithm to create crochet patterns for a variety of surfaces. I start with surfaces of constant curvature: the Euclidean surface and the sphere. Then, I generate patterns for surfaces of revolution by calculating the change in circumference for each row of stitches. My methods suggest an approach to crochet more surfaces such as surfaces whose cross section is not a circle. This research demonstrates how crochet can act as a discrete model of differential geometry. Producing these patterns allows for further research into the surfaces themselves by providing accurate models as …

A Bank Erosion Hazard Index (Behi) Study Of Dry Run Creek, Cedar Falls, Iowa, Cara Wright

Honors Program Theses

Dry Run Creek is a watershed located in Cedar Falls; Iowa and it is on a list of the state's impaired waterways. One reason it may be impaired is that there is excessive erosion in the stream. This study assessed the Bank Erosion Hazard Index of portions of the creek to determine erosion hotspots. The majority of the banks in all the branches had a Low score, meaning that the BEHI was less than 11.9. The minimum BEHI score is O and the maximum score is 40. The lower the score, the better the condition of the bank. Portions of …

Equivalences Of Dessins D'Enfants, Rachel M. Volkert

Honors Program Theses

Dessins d'enfants are bipartite graphs with a cyclic ordering given to the set of edges that meet at each vertex. Merling and Perlis presented a method by which to construct pairs of dessins d'enfants using the permutations induced by the action of a finite group on the cosets of two locally conjugate subgroups of that group. They called these pairs of dessins Gassmann equivalent and investigated some of their properties. First, we discuss several properties of pairs of dessins that imply Gassmann equivalence. Then, using elementwise conjugate subgroups, we introduce and investigate a weaker type of equivalence of dessins, which …

Variable Selection In Nonparametric And Semiparametric Regression Models, Liangjun Su, Yonghui Zhang

Research Collection School Of Economics

This chapter reviews the literature on variable selection in nonparametric and semiparametric regression models via shrinkage. We highlight recent developments on simultaneous variable selection and estimation through the methods of least absolute shrinkage and selection operator (Lasso), smoothly clipped absolute deviation (SCAD) or their variants, but restrict our attention to nonparametric and semiparametric regression models. In particular, we consider variable selection in additive models, partially linear models, functional/varying coefficient models, single index models, general nonparametric regression models, and semiparametric/nonparametric quantile regression models.

Mesoscopic Methods In Engineering And Science, Jos Derksen, Dmitry Eskin, Li-Shi Luo, Manfred Krafczyk

Mathematics & Statistics Faculty Publications

(First paragraph) Matter, conceptually classified into fluids and solids, can be completely described by the microscopic physics of its constituent atoms or molecules. However, for most engineering applications a macroscopic or continuum description has usually been sufficient, because of the large disparity between the spatial and temporal scales relevant to these applications and the scales of the underlying molecular dynamics. In this case, the microscopic physics merely determines material properties such as the viscosity of a fluid or the elastic constants of a solid. These material properties cannot be derived within the macroscopic framework, but the qualitative nature of the …

Barrow Island Ute Guide - Non-Indigenous Invertebrates, Frogs, Reptiles & Weeds, Mike Grimm, Kristofer Collett, Jessica Harrison, Peter Davis, Marc Widmer, Andras Szito, Rob Emery, Peter Mangano, John Botha, David Robinson, Brad Maryan

Biosecurity published reports

Barrow Island, the second largest island in Western Australia, is a Class A Nature Reserve and home to a variety of rare and endangered fauna and flora, some of which occur nowhere else. To protect fauna and flora it is essential workers and visitors to the island are aware of the risks that a non-indigenous species (NIS) poses to the ecological balance of Barrow Island.

Workers and visitors to Barrow Island need to be aware and keep their eyes open for any unusual fauna and flora that might be in accommodation units, recreation areas or the work place. Reports from …

Low Root Zone Temperature Limits Nutrient Effects On Cucumber Seedling Growth And Induces Adversity Physiological Response, Qiu-Yan Yan, Zeng-Qiang Duan, Jing-Dong Mao, Xun Li, Fei Dong

Chemistry & Biochemistry Faculty Publications

Effects of root-zone temperatures (RZT) (12°C-RZT and 20°C-RZT) and different N, P, and K nutrient regimes on the growth, reactive oxygen species (ROS), and antioxidant enzyme in cucumber seedlings were investigated in hydroponics. Strong interactions were observed between RZT and nutrient on the dry weight (P=0.001), root length (P=0.001) and leaf area (P=0.05). Plant dry weights were suppressed at low RZT of 12°C, while higher biomass and growth of cucumber seedlings were produced at elevated RZT of 20°C under each nutrient treatment. Growth indexes (plant height, internode length, root length, and leaf area) at 12°C-RZT had less difference among nutrient …

Trophic Ecology Of Oxygen Minimum Zone Zooplankton Revealed By Carbon And Nitrogen Stable Isotopes, Rebecca Williams

Open Access Dissertations

Oxygen minimum zones (OMZs) are areas in which midwater oxygen concentration can be significantly lower than in non OMZ areas at comparable depths. OMZs are of great interest because of the limits oxygen availability places on life. The potential for OMZ expansion with warming of the oceans has refocused attention on the importance of these areas and their potential impacts on the global carbon cycle. The large open ocean OMZs of the Eastern Tropical Pacific and Arabian Sea are notable for their size, thickness, and the intensity of oxygen depletion (

Here, I use measurements of natural abundance carbon and …

Insects As Indicators Of Environmental Stress, De Anna Estella Beasley

Theses and Dissertations

In the face of climate change-related events and anthropogenic disturbances, understanding the impacts of these events on species richness, abundance and distribution is important for us to mitigate biodiversity loss and better predict consequences for the environment and for human life. Insects are excellent models for understanding the consequences of environmental stress due to the sensitivity of their development and behavior. The overall focus of my dissertation research is the investigation of fluctuating asymmetry and oviposition behavior as indicators of environmental stress. My research includes a meta-analysis of published literature, and empirical research that was part of a collaborative initiative …