Epidemiology Commons^™

Tuberculosis Por Los Ojos De La Vida Aymara: La Correlación Entre Estilo De Vida Y Tuberculosis En Los Aymara Del Norte De Chile, Sam Percy

Independent Study Project (ISP) Collection

Background: Explanations for disparities in health between groups of people are complex, and based in differences in genetics, environment, access to medical care, socioeconomic, educational, and cultural factors. In short a person’s lifestyle is inextricably related to a person’s health and their propensity to contract disease. Members of the indigenous group Aymara who live in Arica, Chile have 6 times the rate of morbidity from Tuberculosis (TB) as non-Aymara and 9 times the rate of mortality from the disease. This study examined if there was a link between the rate of TB amongst the Aymaran people and the way Aymarans …

Nonparametric Incidence Estimation From Prevalent Cohort Survival Data, Marco Carone, Masoud Asgharian, Mei-Cheng Wang

COBRA Preprint Series

Incidence is an important epidemiologic concept particularly useful in assessing an intervention, quantifying disease risk, and planning health resources. Incident cohort studies constitute the gold-standard in estimating disease incidence. However, due to material constraints, data are often collected from prevalent cohort studies whereby diseased individuals are recruited through a cross-sectional survey and followed forward in time. We discuss the identifiability of measures of incidence in the context of prevalent cohort survival studies and derive nonparametric maximum likelihood estimators and their asymptotic properties. The proposed methodology accounts for calendar-time and age-at-onset variation in disease incidence while also addressing common complications arising …

The Importance Of Scale For Spatial-Confounding Bias And Precision Of Spatial Regression Estimators, Christopher J. Paciorek

Harvard University Biostatistics Working Paper Series

Increasingly, regression models are used when residuals are spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on the bias and precision of regression coefficients, developing a simple framework in which to understand the key issues and derive informative analytic results. When the spatial residual is induced by an unmeasured confounder, regression models with spatial random effects and closely-related models such as kriging and penalized splines are biased, even when the residual variance components are known. Analytic and simulation results show how the bias …

Analysis Of Randomized Comparative Clinical Trial Data For Personalized Treatment Selections, Tianxi Cai, Lu Tian, Peggy H. Wong, L. J. Wei

Harvard University Biostatistics Working Paper Series

No abstract provided.

Insulinoma Presenting As An Unusual Cause Of Marital Discord, Alfred F. Shwayhat, David Brett-Major, John A. Poremba

Journal Articles: Epidemiology

Months before this patient’s near collapse, the metabolic derangements caused by his cancer manifested in his marriage. This case demonstrates the need to consider insulinoma in healthy appearing patients who experience behavioral disturbances that otherwise might be treated only with counseling.

Ua94/6/1 Student / Alumni Personal Papers Western Kentucky University Small Collections, Wku Archives

WKU Archives Collection Inventories

Small collections of personal papers and oral histories relating to the Western Kentucky University.

Analyzing Adherence To Prenatal Supplements: Does Pill Count Measure Up?, Kristie Elizabeth Appelgren

MUSC Theses and Dissertations

Background: Results of a trial of prenatal Vitamin D supplementation are analyzed for associations of pill count data with serum-based measures of adherence. Obiective: It is hypothesized that adherence as measured by pill count will have a significant association with serum-based measures of adherence. Design: The study from which the data for this analysis were derived is a large randomized, controlled, and double-blinded trial of vitamin D supplements in pregnant women. The women have been stratified by race and randomized into three groups, which receive a 400IU (control), 20001U, or 40001U dose of vitamin D[subscript 3] once daily. Women enter …

Ua3/1/2/1 President's Office-Cherry - Correspondence - General, Wku Archives

WKU Archives Collection Inventories

General correspondence regarding Western Kentucky University. Incoming letters are mainly addressed to Henry Hardin Cherry. Responses are made by Cherry and occasionally by faculty and staff. The president's secretary Mattie McLean is the writer for some of the letters signed by Cherry.

Some of Cherry's personal papers are also found in this series most notably those pertaining to his political aspirations and two candidacies for the Kentucky governorship. Copies of outgoing correspondence begin to appear in Box 1, Folder 50.

Preventing Cervical Cancer: Challenges To Implementing Hpv Vaccine Strategies Among Medically Underserved Populations, Sharon M. Bond

MUSC Theses and Dissertations

Cervical cancer is a major health problem and the second leading cause of cancer deaths among women worldwide. The purposes of this dissertation are threefold; to examine cervical cancer screening methods used in developing countries, evaluate prevailing attitudes toward new human papillomavirus (HPV) vaccines and share results from a pretest of two instruments designed to measure knowledge, attitudes and beliefs about cervical cancer, human papillomavirus infection and the new vaccines among medically underserved populations. In manuscript I, direct visual inspection (DVI) is a method used to screen for cervical cancer in developing countries where population-based Papanicolaou (Pap) screening is unaffordable …

War Of The Worlds: Our Worlds Are Colliding And Infectious Disease Is Winning - Emerging Diseases And The One Health Initiative, Richard French

The University Dialogue

No abstract provided.

When To Spray: A Time-Scale Calculus Approach To Controlling The Impact Of West Nile Virus, Diana Thomas, Marion Weedermann, Lora Billings, Joan Hoffacker, Robert Washington-Allen

Department of Mathematics Faculty Scholarship and Creative Works

West Nile Virus (WNV) made its initial appearance in the New York City (NYC) metropolitan area in 1999 and was implicated in cases of human encephalitis and the extensive mortality in crows (Corvus sp.) and other avian species. Mosquitoes were found to be the primary vectors and NYC’s current policy on control strategies involved an eradication program that depends on the synchronicity of the summer mosquito population’s increases with the occurrence of cases in humans. The purpose of this paper is to investigate whether this is the most effective control strategy because past mathematical models assumed discrete behavior that …

Characteristics Of Children Attending Asthma Camp -- American Lung Association (Ala) In Nevada, 2008, Priyank Shetty

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study is based on data provided by American Lung Association (ALA) on the children participating in summer asthma camp in Las Vegas and Reno, Nevada. 56 children participated in the camp in 2008. Universal Health History Form was used which is a comprehensive form to be filled out by parent and physician. Pre-test and Post-test Asthma forms were used to ascertain asthma knowledge before and after the camp.

The purpose of this study was to assess the trigger knowledge of the camp attendees and the measure of agreement between Physician and Parent report of child's asthma severity. In Nevada, …

Hiv Rates In The State Of Georgia: A Growing Threat Among Predominately African American Populations, Swati Raychowdhury, Stuart H. Tedders

Epidemiology: Faculty Publications (2002-2018)

Background: US rates of HIV/AIDS continue to rise with over 55% of new cases identified in southern states in 2003. The objective of this study was to determine the magnitude of HIV/AIDS cases in rural southeast Georgia in comparison to urban areas of the state.

Methods: County level data was acquired using OASIS. Rates of HIV infections by gender and race (black vs. white) were aggregated over a five year period (2000–2005) and indirectly adjusted using Georgia as the standard. Rates for rural counties, (populations less than 35,000), were statistically compared to urban rates (α = 0.05).

Results: HIV infections …

Validation Of Inverse Seasonal Peak Mortality In Medieval Plagues, Including The Black Death, In Comparison To Modern Yersinia Pestis-Variant Diseases, Mark R. Welford, Brian H. Bossak

Earth, Environment & Sustainability: Faculty Publications

Background: Recent studies have noted myriad qualitative and quantitative inconsistencies between the medieval Black Death (and subsequent ‘‘plagues’’) and modern empirical Y. pestis plague data, most of which is derived from the Indian and Chinese plague outbreaks of A.D. 1900615 years. Previous works have noted apparent differences in seasonal mortality peaks during Black Death outbreaks versus peaks of bubonic and pneumonic plagues attributed to Y. pestis infection, but have not provided spatiotemporal statistical support. Our objective here was to validate individual observations of this seasonal discrepancy in peak mortality between historical epidemics and modern empirical data.

Methodology/Principal Findings: …

Trends In Asthma Health Care Utilization At University Medical Center (Umc) Of Southern Nevada In Las Vegas, 2000-2007, Aishia Tennille Henderson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lifetime asthma prevalence is the physician diagnosis of asthma while current asthma prevalence is the existing asthma symptoms. In Nevada, the pediatric current and lifetime asthma prevalence rates were 7.1% and 11.8% in 2006. Similarly, the adult current and lifetime asthma prevalence rates were 6.9% and 13.4% in 2007.

Characterization studies examining trends of asthma health care utilization for children and adults are not well studied for Las Vegas, Nevada. This project determined if trends in asthma admissions at UMC hospital of Southern Nevada in Las Vegas have increased longitudinally across years and characterizes which demographic subgroups are disproportionately affected …

An Evaluation Of Lead Hazards In Pre-1978 Residental Housing Within Clark County, Nevada, Usa, Erika Raquel Torres

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lead poisoning remains a public health concern due to leads persistence in the environment from anthropogenic uses. Initial efforts to address the impacts of lead on vulnerable communities have included secondary prevention measures which typically occur after a child has been poisoned. However, in recent years there has been a pragmatic shift toward primary prevention efforts.

This study evaluates lead hazards identified through primary prevention activities in residential housing within Clark County, Nevada, USA. It is the first study to systematically address and evaluate pre-1978 housing in Southern Nevada. Risk assessments were conducted in 81 dwellings built prior to 1979 …

Sand Fly Fever: What Have We Learned In One Hundred Years?, David Brett-Major, David M. Claborn

Journal Articles: Epidemiology

Sand fly fever has severely impacted military missions in southern Europe and the Middle East for hundreds of years. After a brief respite following the malaria eradication programs of World War II, it has returned as a significant disease among residents in and travelers to the Mediterranean rim. It is a more severe disease now, with potential vectors in the United States. Sand fly fever is discussed in terms of its viruses, vectors, disease, control, and potential domestic impact.

Antibiotic Prophylaxis For Leptospirosis, David Brett-Major, Robert J. Lipnick

Journal Articles: Epidemiology

BACKGROUND: Leptospira infection is a global zoonosis with significant health impact for agricultural workers and those persons whose work or recreation takes them into endemic areas.

OBJECTIVES: This systematic review assessed the current literature for evidence for or against use of antibiotic prophylaxis against Leptospira infection (leptospirosis).

SEARCH STRATEGY: The authors searched The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and SCI-Expanded as well as relevant professional society meeting abstracts until January 2009.

SELECTION CRITERIA: Prospective, randomised clinical trials studying antibiotic prophylaxis against leptospirosis were selected.

DATA …

Foodborne Or Pandemic: An Analysis Of The Transmission Of Norovirus-Associated Gastroenteritis And The Role Of Food Handlers, M. S. Dreyfuss

Walden Dissertations and Doctoral Studies

This study examined the strength of association between food workers and food to norovirus in comparison to bacteria associated with foodborne-related gastroenteritis by whether norovirus had a direct (physical evidence), indirect (statistical evidence), or suspect (neither of the two) association with food or food handlers. The Centers for Disease Control and Prevention considers norovirus to cause the largest number of foodborne-related gastroenteritis cases in the United States. The association of norovirus with foodborne outbreaks through its information data collection form focuses on the food worker as the typical source. Yet, many outbreaks are not foodborne in nature. The gap in …

A Small Sample Correction For Estimating Attributable Risk In Case-Control Studies, Daniel B. Rubin

U.C. Berkeley Division of Biostatistics Working Paper Series

The attributable risk, often called the population attributable risk, is in many epidemiological contexts a more relevant measure of exposure-disease association than the excess risk, relative risk, or odds ratio. When estimating attributable risk with case-control data and a rare disease, we present a simple correction to the standard approach making it essentially unbiased, and also less noisy. As with analogous corrections given in Jewell (1986) for other measures of association, the adjustment often won't make a substantial difference unless the sample size is very small or point estimates are desired within fine strata, but we discuss the possible utility …

Social Support, Weight Loss Attempts And Satisfaction, Allison Drew

Theses and Dissertations

Objective: The purpose of this study was to determine the extent to which the presence of social support correlates with attempts at weight loss in the past 12 months, attempts not to gain weight in the past 12 months, and participants’ satisfaction with their weight status. Methods: We used a cross-sectional study design using data collected by the 2003-2004 and 2005-2006 National Health and Nutrition Examination Surveys (NHANES) (CDC). For this study we included males and females, of multiple ethnicities, and a range of ages from 40 to 70 + years. Participants with missing data on height and weight were …

Medicare Managed Care Penetration And Prevalence Of Older Adult Disability, Christine Moe

Theses and Dissertations

OBJECTIVE: To investigate the relationship between Medicare Managed Care (MMC) penetration and percentage of disability in older adults (individuals age 65 and older). Considering disability as an indicator of one or more unsuccessfully managed chronic diseases, this study investigates the assumption that managed care improves coordination of care, as well as access to preventive care. If managed care’s mandate is being met, then it should be evidenced in decreased prevalence of older adult disability. METHOD: Taking an ecological approach, this study used data from the Agency for Healthcare Research and Quality (AHRQ, 2003) to compare the percentage of older adult …

Fetal And Early Neonatal Death: Do The Determinants Vary?, Ashley Carter

Theses and Dissertations

Purpose: To compare the determinants and distribution of fetal and early neonatal deaths in the Commonwealth of Virginia. Background: Much attention is devoted to reducing the infant mortality rate which was declining up until 2002. The recent rise was parsed and found to stem from an increase in deaths during the early neonatal period. Fetal deaths are not well understood and are not routinely included when evaluating infant mortality. Methods: Using data collected from 2001 to 2006 fetal death and linked infant birth and death certificates by the Virginia Department of Health, crude mortality rates and leading causes of death …

Do Black Msm Have More Idu And Hiv Positive Partners Compared To White Men Having Sex With Men ?, Shankar Krishnappa

Theses and Dissertations

Objectives: This study estimates the proportion of intravenous drug use (IDU) partners and HIV positive sexual partners among black and white and examine the association between repeat HIV testing and sex with high risk partners. Methods: A cross-sectional study of MSM was conducted by using pooled data from counseling, Testing, Referral services in Virginia, USA 2002-2007. Results: We obtained a sample of 19679 MSM out of which 10924(56%) and 6739(34%) were white and black MSM respectively. The proportion of IDU partners and HIV positive partners were among white MSM (5% and 11%) and black MSM (3% and 9%) respectively. Age …

Season Of Birth And Risk For Schizophrenia, Seth Roberts

Theses and Dissertations

Background: Schizophrenia is a chronic, debilitating mental disorder characterized by positive (e.g., hallucinations, delusions) and negative (e.g., catatonia, flat affect) signs and symptoms. Many studies suggest that individuals born in winter or spring months are at increased risk for schizophrenia. Study Objectives: 1) To determine whether season of birth affects risk for schizophrenia in the Irish Study of High Density Schizophrenia Families (ISHDSF). 2) To examine, by computer simulation, power to detect genetic associations with schizophrenia under a variety of conditions and using different analytic strategies. 3) To test whether specific genes are associated with schizophrenia in the Irish Case …

Effect Of Metro Living On Oral Cancers In Virginia: 2001-2005, Preeti Sastry

Theses and Dissertations

Background: Forty percent of all head and neck cancers occur in the oral cavity. According to ICD-O (International classification of diseases for oncology) C00-C14 includes cancers of the lip, oral cavity and pharynx. Studies have indicated that increased population density or Metro living have increased oral cancer incidence. The objectives of this study are to look at the distribution of Oral and Oro pharyngeal Cancers in Virginia from 2001-2005 The study aims to determine if there is an association between metro living (beale code 3) and advanced Oral Cancers. This study is also being done to determine if Metro living …

Spatial Misalignment In Time Series Studies Of Air Pollution And Health Data, Roger D. Peng, Michelle L. Bell

Johns Hopkins University, Dept. of Biostatistics Working Papers

Time series studies of environmental exposures often involve comparing daily changes in a toxicant measured at a point in space with daily changes in an aggregate measure of health. Spatial misalignment of the exposure and response variables can bias the estimation of health risk and the magnitude of this bias depends on the spatial variation of the exposure of interest. In air pollution epidemiology, there is an increasing focus on estimating the health effects of the chemical components of particulate matter. One issue that is raised by this new focus is the spatial misalignment error introduced by the lack of …

Parental Influences In Child Obesity, Janel Lynn Calinisan

Loma Linda University Electronic Theses, Dissertations & Projects

One of the greatest concerns in American society is peoples’ health. In the past several years there has been an overwhelming increase in obesity in Americans. This concern relates not only to adults, but also to children, as more are found to be overweight. Many factors have been suggested as to why more children are becoming obese, including parenting, demographics, physical activity, nutrition, and biological factors. Studies have shown that parental influence or involvement can be related to child obesity such that neglected children were more likely to be obese in adolescence and sustain it through adulthood. In order to …

Exploratory Study Of Environmental Effects On Physical Activity And Overweight In Older Women: Research Update, Heather A. Whitcomb, Kosuke Tamura, Lauren Milius, Francine Laden, Steve Melly, Peter James, Robin Puett, Ellen Cromley, Eran Ben-Joseph, Philip J. Troped

GIS Day

Background: Physical inactivity and obesity are major public health issues. Recent studies have provided evidence that attributes of the built environment influence physical activity among adults and that factors such as greater urban sprawl are related to overweight and obesity. Few studies have developed objective individual-level measures of the built environment, a geographic scale that may be more relevant to certain types of physical activity, such as walking. In addition, further research is needed to assess the associations of both objective and perceived environmental factors with physical activity. In this 2-year exploratory study funded by the National Cancer Institute, we …

Filariasis Limfatik Di Kelurahan Pabean Kota Pekalongan, Tri Ramadhani

Kesmas

Filariasis limfatik masih merupakan masalah kesehatan masyarakat di Indonesia, khususnya di Kota Pekalongan. Hal ini ditandai dengan semakin meningkatnya angka mikrofilaria dan perluasan daerah dengan kasus filariasis limfatik.Tujuan penelitian adalah untuk mengetahui situasi filariasis limfatik di Kelurahan Pabean Kota Pekalongan. Penelitian ini meliputi penduduk dan agent, dalam periode sekitar enam bulan (Juli-Desember 2007) dengan disain studi cross sectional. Pada penelitian ini dilakukan pemeriksaan klinis, survei darah jari dan identifikasi parasit penyebab filariasis limfatik. Hasil penelitian menunjukkan angka mikrofilaria (3,4) angka kesakitan akut filaria (0,4 %) yang tinggi, tetapi angka kesakitan kronis filaria rendah (0,00 %). Parasit penyebab filariasis di Kelurahan …