Public Health Commons^™

A164: Research On The Matching Of Talent Supply And Demand In China's Sports Industry, Yunxia Ding, Zhejing Ding

International Journal of Physical Activity and Health

Background/Purpose: Developing a systematic approach is essential for the sports industry development. Talent optimization plays a crucial part in this process. The present study gathered talent-related data pertaining to China's sports industry between 2015 and 2021.

Method: This study used the structural deviation coefficient model to analyze the supply and demand structural matching of data related to China's sports industry and talents from 2015–2021. The gray prediction model was used to predict and analyze the demand for talents in China's sports industry in the middle and late 14th Five-Year Plan. The participation of relevant subjects in the systematization of the …

A169: Association Between Daily Steps And Frailty In Older Adults: A Meta-Analysis, Lingsong Kong, Pardis Parvizi, Shivangi Bajpai, Amanda Paluch

International Journal of Physical Activity and Health

Background/Purpose: Frailty is a significant health challenge for the aging population, increasing vulnerability to adverse health outcomes such as chronic disease, falls, disability, and mortality. Early detection and monitoring of frailty are critical for effectively managing frailty. Daily steps, as a measure of physical activity, hold valuable information about health status and may serve as an indicator of frailty. This study aimed to examine the association between daily steps and frailty in older adults.

Method: PubMed, SPORTDiscus, and Web of Science databases were searched for published studies up to June 2023. The search terms were ("daily step" or "steps per …

A170: Effects Of Exercise On Liver Function And Inflammatory Markers In Nafld Patients: A Meta-Analysis, Siyang Wang, Chunyan Xu, Ye Yue

International Journal of Physical Activity and Health

Background/Purpose: Nonalcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition globally, often linked to sedentary behaviors and central obesity. It is characterized by the activation of multiple signaling cascades leading to inflammation, which plays a critical role in the occurrence and progression of NAFLD liver damage. With the absence of targeted pharmacological treatments, lifestyle and dietary adjustments remain primary interventions for many patients. However, the optimal exercise intensity for managing NAFLD remains unclear, with conflicting evidence on its effectiveness in modulating inflammation. This study aimed to clarify the impact of different exercise types and intensities on liver function …

A171: The Effects Of Qigong On Balance And Fall Prevention In Older Adults: A Systematic Review, Rong Zhang, Zilong Fang

International Journal of Physical Activity and Health

Background/Purpose: Falls are the second leading cause of unintentional injury deaths globally, with approximately 684,000 deaths from falls each year, and older adults are at the highest risk of death or serious injury due to imbalance, with risk increasing with age. Coupled with the accelerating global aging process, the safety of the elderly population due to fall imbalance should be taken seriously. Qigong, one of the classic traditional Chinese exercises, is beneficial for improving the physical fitness of the elderly. However, few studies have reported the effect of Qigong on fall risk in older adults. Therefore, we conducted this systematic …

A172: Performance Of Muscle Explosive And Maximal Strength In Trampoline Athletes At Different Levels Of Competition, Mengzi Sun, Fangtong Zhang, Feng Qu, Xinglong Zhou, Wenhui Mao

International Journal of Physical Activity and Health

Purpose: To study the differences in lower limb muscle explosive and maximal strength among trampoline athletes at different levels of competition.

Methods: A total of fifteen trampoline athletes, comprising seven elite and eight non-elite athletes, participated in this project. Lower limb explosive strength was assessed using the countermovement jump (CMJ) test. Maximal strength was evaluated by the MicroFet portable system. The maximal strength of the hip, knee, and ankle were measured and standardized by weight. Independent t-tests were employed to examine the differences between the two groups. Cohen’s d was used to evaluate the related effect size. Small, medium, and …

A168: The Effects Of Physical Activity And Family Environment On Executive Function In Preschool Children, Siyi Zhang, Chunrong Wang, Dongmei Luo, Sha Qu, Xing Zhao

International Journal of Physical Activity and Health

Background/Purpose: Based on the investigation and analysis of the current situation of physical activity, the family objective environment, and executive function development of children aged 4–6 years, this study analyzed the correlation between the three, so as to explore the influence of family objective environment and physical activity on executive function, and provide a reference for families and kindergartens to formulate effective interventions to improve the level of physical activity and executive function of preschoolers.

Method: A total of 123 preschool children aged 4–6 years old in a kindergarten in Beijing were selected as study participants. The Acti Graph GT3X+ …

A166: Effects Of Mind-Body Exercises On Women Breast Cancer Survivors: A Systematic Review And Network Meta-Analysis, Peng Pei, Liqing Zeng, Yan Wang

International Journal of Physical Activity and Health

Background/Purpose: Breast cancer (BC) is one of the most common malignant tumors in the world and the leading cause of cancer-related death in women. Mind-body exercise (MBE) is a non-pharmacological and low-intensity multimodal form of exercise with reliable benefits for improving quality of life (QOL) and relieving cancer-related symptoms. Currently, there is a lack of consensus in clinical studies on the optimal form of MBE to improve QOL and cancer-related fatigue (CRF) in BC survivors. Therefore, this network meta-analysis (NMA) aimed to quantitatively analyze and rank different MBE interventions for women BC survivors, thereby improving the accuracy and generalization of …

A175: Effects Of Physical Activity Interventions On Physical Fitness In Chinese Preschool Children: A Systematic Review, Jintao Hong, Jingjing Wang, Sitong Chen, Jie Feng

International Journal of Physical Activity and Health

Background: The early years are a critical period for the development of health-related physical fitness (PF). National surveillance data showed that PF decreased among Chinese preschool children aged 3-6 years. There is a widespread call for effective physical activity (PA) intervention strategies for this age group. Nevertheless, the depth and breadth of the evidence on such interventions in Chinese preschoolers remains relatively small. Therefore, the present systematic review aimed to investigate the effects of PA interventions on PF in typically developing Chinese young children.

Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a …

A167: The Impact Of Physical Exercise On Subjective Well-Being In Elementary Students: A Chain Mediation Model, Xinwei Wu, Mengyue Hu, Youfa Li

International Journal of Physical Activity and Health

Purpose: Physical exercise has been recognized for its beneficial effects on emotional states, with previous research highlighting its positive correlation with subjective well-being. However, the pathways through which physical exercise influences subjective well-being remain unclear. This study aimed to investigate the mechanisms by which physical exercise impacted subjective well-being among elementary school students, analyzing the chain mediating role of peer relationships and depression.

Methods: The study sampled 15,538 fourth-grade students from 312 elementary schools in Taiyuan City, including 7,838 boys (50.5%) and 7,690 girls (49.5%), with an average age of 10.38 ± 0.56 years. Data collection was conducted on October …

A176: Meta-Analysis Of The Effects Of Phototherapy On Sleep Quality Across Different Populations, Zhen Chen, Wenqiang Wu

International Journal of Physical Activity and Health

Background: Sleep, a fundamental physiological need for humans, significantly impacts an individual's physical and mental health. Phototherapy, a non-pharmacological intervention, has been extensively researched in recent years to improve sleep quality. This study aimed to systematically evaluate the effects of phototherapy on sleep quality across different populations through a meta-analysis, using Pittsburgh Sleep Quality Index as the outcome measure, thereby providing a scientific basis for improving the population health levels and life quality.

Method: As of March 1, 2024, this study conducted a systematic search of four databases: Web of Science, PubMed, Embase, and CNKI. A comprehensive set of inclusion …

A177: Association Between Physical Activity And The Risk Of Depression Among Middle And Older Chinese People, Yunqing Zhang

International Journal of Physical Activity and Health

Purpose: Relevant studies have shown that insufficient physical activity (PA) is associated with the risk of depression in middle-aged and elderly populations, but the relationship between different levels of PA and the risk of depression remains unexplored. Therefore, the objective of this study was to explore the relationship between different levels of PA and depression risk among middle-aged and older adults in China.

Methods: The survey data of this study was based on the 2020 China Health and Retirement Longitudinal Study (CHARLS). A total of 13,316 middle-aged and elderly community residents aged 45 years or older with complete values of …

A178: Effect Of Aerobic Exercise Intervention On Anxiety In College Students: A Systematic Review, Yiming Chen, Shengting Dai, Xinming Ye

International Journal of Physical Activity and Health

Background/Purpose: The role of exercise interventions in the treatment of psychiatric disorders is receiving increased attention, and the positive protective effect of aerobic exercise on anxiety symptoms has now been extensively demonstrated. This study aimed to investigate the systematic evaluation of the effects of different aerobic exercise interventions on anxiety symptoms in college students.

Method: Using keywords such as “physical activity,” “anxiety,” and “college students” screened Randomized controlled trials (RCT) published until February 2024 in three databases: PubMed, Web of Science, and Scopus. A total of 5073 studies were retrieved after systematically searching individual databases. After removing duplicate literature, 4112 …

A173: An Experimental Study Of The Effects Of Exercise Intervention On Executive Function In Obese Adolescents, Lingling Hu, Hengchan Yin, Lei Cui, Qiqi Shen

International Journal of Physical Activity and Health

Background: Executive function (EF) is an important component of cognitive function, referring to a higher-level cognitive process that coordinates and controls various basic cognitive processes when completing complex cognitive tasks. It includes three sub-functions: inhibition, working memory, and cognitive flexibility. Globally, high rates of overweight and obesity remain a public health issue. Previous studies have shown that, compared to adolescents with healthy weight, adolescents with obesity have poorer inhibitory function in EF. In addition, the effectiveness of the exercise intervention is seen in the normal adolescent population as well as in special adolescents with poor EF. However, there have been …

A181: The Realistic Path Of Green Sports To Boost Urban Development, Xinyu Huang

International Journal of Physical Activity and Health

Green sports is an emerging form of sports that pursues the integrated development and harmonious coexistence of sport, humanities, and ecology. As the interaction between the green sports industry and cities becomes increasingly closer, it is of great practical significance to explore how the development path of green sports can enhance urban development. Green sports have the characteristics of close industrial connection, environmental protection, low carbon, and a huge consumption base.

It can promote the transformation of social, economic, and ecological models of cities by bringing into play the economic vitality, social benefits, and ecological benefits of the green sports …

A180: The Effects Of Weight Control By Hypoxia On Judo Athletes With Hiit, Liying Huang

International Journal of Physical Activity and Health

Purpose: High-intensity interval training (HIIT) is recognized as an effective means of fat reduction, and HIIT is also used in the pre-competition weight control of judo. In addition, hypoxic adaptation can reduce blood lipids, maintain exercise capacity, and improve physical function. Therefore, this study explored the effects of weight control by hypoxia on judo athletes with HIIT by observing the changes of body composition, blood lipids, exercise ability and body function, so that to explore an innovative method of weight control pre-competition for judo athletes.

Methods: 12 female athletes of the provincial judo team preparing for the 2023 Guangdong Provincial …

A018: Dual-Process Advantages Of Ball Players In Sport-Related Domains, Xuechen Mao

International Journal of Physical Activity and Health

Background: Based on a dual-process framework, two qualitatively different modes of processing guide human behaviour. Type 1 processes refer to automatic, unconscious processing that can be responsible for Task 1, while Type 2 processes refer to controlled, conscious processing required by Task 2. Although many existing sport psychology studies emphasize that the dual-process model can be applied to the sports domain, this application has shortcomings. The first debate of this application is whether dual-process advantages in athletes are limited to sport-specific realms. Furthermore, although the dual-process framework pays more attention to automatic processes (Type 1 processes), it loses sight of …

A027: Does Participation In Sports Competitions Enhance Medical Students' Interprofessional Teamwork?, Guochun Liu, Zhiling Shen

International Journal of Physical Activity and Health

Background: Healthcare systems are complex linkages, and efficient interprofessional collaboration is essential to their efficiency, safety, and quality. The ability of medical students to collaborate across professions directly impacts future healthcare delivery practices. Physical education programmes provide a simple and easy way for medical students to develop interprofessional collaboration that can be translated into future team performance in clinical settings. To test the effectiveness of the physical education programme "competition instead of examination" in improving the teamwork ability of medical students.

Method: Using a quasi-experimental intervention design, 188 students were recruited from five classes to complete a teamwork scale consisting …

A047: Research On The Structure And Scale Of Service Quality Of Sports Park, Liping Xu, Zhihua Yin, Jian Wang

International Journal of Physical Activity and Health

Background/Purpose: Since the "14th Five-Year Plan" period, with the vigorous promotion of China and the provincial and municipal governments, the number of sports parks has shown a continuous positive trend of growth. While accelerating the construction progress, how to improve the service quality of sports parks should become the primary issue that needs to be solved to promote the sustainable and healthy development of sports parks. Therefore, based on the perspective of public demand, this study formed a scientific assessment scale by exploring the specific content structure contained in the service quality of sports parks, to promote the high-quality development …

Biological Validation Of Peak-Width Of Skeletonized Mean Diffusivity As A Vcid Biomarker: The Markvcid Consortium, Alison M Luckey, Saptaparni Ghosh, Chen-Pin Wang, Alexa Beiser, Rebecca Bernal, Zhiguang Li, Djass Mbangdadji, Elyas Fadaee, Haykel Snoussi, Angel Gabriel Velarde Dediós, Hector A Trevino, Monica Goss, Laura J Hillmer, Christopher E Bauer, Adam M Staffaroni, Lara Stables, Marilyn Albert, Jayandra J Himali, Thomas H Mosley, Lars Forsberg, Vilmundur Guðnason, Baljeet Singh, Herpreet Singh, Kristin Schwab, Joel H Kramer, Gary A Rosenberg, Karl G Helmer, Steven M Greenberg, Mohamad Habes, Danny J J Wang, Brian T Gold, Hanzhang Lu, Arvind Caprihan, Myriam Fornage, Lenore J Launer, Konstantinos Arfanakis, Sudha Seshadri, Charles Decarli, Pauline Maillard, Claudia L Satizabal

Faculty, Staff and Student Publications

BACKGROUND: Peak-width of skeletonized mean diffusivity (PSMD), a neuroimaging marker of cerebral small vessel disease (SVD), has shown excellent instrumental properties. Here, we extend our work to perform a biological validation of PSMD.

METHODS: We included 396 participants from the Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia (MarkVCID-1) Consortium and three replication samples (Cohorts for Heart and Aging Research in Genomic Epidemiology = 6172, Rush University Medical Center = 287, University of California Davis Alzheimer's Disease Research Center = 567). PSMD was derived from diffusion tensor imaging using an automated algorithm. We related PSMD to a composite measure …

Understanding The Rising Use Of Fentanyl And The Impact Social Media Plays, Richard Omar Lopez

Electronic Theses, Projects, and Dissertations

This study examines how social media platforms like Reddit can be utilized to compare the discourse around fentanyl and recreational drug use. A dataset of 2549 personal experience posts were collected on fentanyl and other recreational drug use. Where the methodology included targeted queries, text processing, and natural language process (NLP) techniques such as sentiment analysis and topic modeling. Results indicate that fentanyl related discourse on Reddit was more likely to carry a cautious or neutral sentient, emphasizing its health risks or addiction. Contrasting the more positive sentiment recreational drugs carry, especially marijuana. Finding that Reddit plays a vital role …

Discrimination, Sexual Orientation, And Alcohol Amongst Latine, Brian Juarez

Electronic Theses, Projects, and Dissertations

Existing research acknowledges the influence of discrimination on alcohol use, this study emphasizes the equally significant role of sexual orientation on alcohol use. Associations between these factors and alcohol consumption demonstrate the necessity for ongoing research to analyze their intricate relationships and subsequent health outcomes. This study highlights the crucial need for an in-depth exploration of discrimination as well as marginalized identities as contributing factors in alcohol consumption.

Using a quantitative approach to assess secondary data gathered from the National Alcohol Surveys (NAS), this paper underscores the importance of a comprehensive and timely approach to research the multifaceted impact of …

Service Provider Perceptions Of Systems Serving Individuals Experiencing Homelessness: A Needs Assessment And Strategic Plan In Johnson City, Tn, Opal Frye-Clark

Electronic Theses and Dissertations

This Integrated Learning Experience (ILE) investigates service providers' perceptions of Johnson City, Tennessee's homelessness services, aiming to inform a city-wide strategic plan for reduction. Employing a mixed-methods approach, the study gathered qualitative data through in-depth interviews with service providers in 2022 and quantitative data via a 2024 survey. The research focused on those directly involved in serving or significantly influencing the lives of individuals experiencing homelessness (IEH). Three key aims guided the investigation: (1) To analyze provider perspectives to identify community assets, opportunities, barriers, and unmet needs, informing a comprehensive needs assessment; (2) To refine these findings through SWOT analysis …

Global And Risk-Group Stratified Well-Being And Mental Health During The Covid-19 Pandemic In Adults: Results From The International Coh-Fit Study, Marco Solmi, Trevor Thompson, Andrés Estradé, Agorastos Agorastos, Joaquim Radua, Samuele Cortese, Elena Dragioti, Davy Vancampfort, Lau Caspar Thygesen, Harald Aschauer, Monika Schlögelhofer, Elena Aschauer, Andres Schneeberger, Christian G Huber, Gregor Hasler, Philippe Conus, Kim Q Do Cuénod, Roland Von Känel, Gonzalo Arrondo, Paolo Fusar-Poli, Philip Gorwood, Pierre-Michel Llorca, Marie-Odile Krebs, Elisabetta Scanferla, Taishiro Kishimoto, Golam Rabbani, Karolina Skonieczna-Żydecka, Paolo Brambilla, Angela Favaro, Akihiro Takamiya, Leonardo Zoccante, Marco Colizzi, Julie Bourgin, Karol Kamiński, Maryam Moghadasin, Soraya Seedat, Evan Matthews, John Wells, Emilia Vassilopoulou, Ary Gadelha, Kuan-Pin Su, Jun Soo Kwon, Minah Kim, Tae Young Lee, Oleg Papsuev, Denisa Manková, Andrea Boscutti, Cristiano Gerunda, Diego Saccon, Elena Righi, Francesco Monaco, Giovanni Croatto, Guido Cereda, Jacopo Demurtas, Natascia Brondino, Nicola Veronese, Paolo Enrico, Pierluigi Politi, Valentina Ciappolino, Andrea Pfennig, Andreas Bechdolf, Andreas Meyer-Lindenberg, Kai G Kahl, Katharina Domschke, Michael Bauer, Nikolaos Koutsouleris, Sibylle Winter, Stefan Borgwardt, Istvan Bitter, Judit Balazs, Pál Czobor, Zsolt Unoka, Dimitris Mavridis, Konstantinos Tsamakis, Vasilios P Bozikas, Chavit Tunvirachaisakul, Michael Maes, Teerayuth Rungnirundorn, Thitiporn Supasitthumrong, Ariful Haque, Andre R Brunoni, Carlos Gustavo Costardi, Felipe Barreto Schuch, Guilherme Polanczyk, Jhoanne Merlyn Luiz, Lais Fonseca, Luana V Aparicio, Samira S Valvassori, Merete Nordentoft, Per Vendsborg, Sofie Have Hoffmann, Jihed Sehli, Norman Sartorius, Sabina Heuss, Daniel Guinart, Jane Hamilton, John Kane, Jose Rubio, Michael Sand, Ai Koyanagi, Aleix Solanes, Alvaro Andreu-Bernabeu, Antonia San José Cáceres, Celso Arango, Covadonga M Díaz-Caneja, Diego Hidalgo-Mazzei, Eduard Vieta, Javier Gonzalez-Peñas, Lydia Fortea, Mara Parellada, Miquel A Fullana, Norma Verdolini, Eva Andrlíková, Karolina Janků, Mark J Millan, Mihaela Honciuc, Anna Moniuszko-Malinowska, Igor Łoniewski, Jerzy Samochowiec, Łukasz Kiszkiel, Maria Marlicz, Paweł Sowa, Wojciech Marlicz, Georgina Spies, Brendon Stubbs, Joseph Firth, Sarah Sullivan, Asli Enez Darcin, Hatice Aksu, Nesrin Dilbaz, Onur Noyan, Momoko Kitazawa, Shunya Kurokawa, Yuki Tazawa, Alejandro Anselmi, Cecilia Cracco, Ana Inés Machado, Natalia Estrade, Diego De Leo, Jackie Curtis, Michael Berk, Andre F Carvalho, Philip Ward, Scott Teasdale, Simon Rosenbaum, Wolfgang Marx, Adrian Vasile Horodnic, Liviu Oprea, Ovidiu Alexinschi, Petru Ifteni, Serban Turliuc, Tudor Ciuhodaru, Alexandra Bolos, Valentin Matei, Dorien H Nieman, Iris Sommer, Jim Van Os, Therese Van Amelsvoort, Ching-Fang Sun, Ta-Wei Guu, Can Jiao, Jieting Zhang, Jialin Fan, Liye Zou, Xin Yu, Xinli Chi, Philippe De Timary, Ruud Van Winkel, Bernardo Ng, Edilberto Peña De León, Ramon Arellano, Raquel Roman, Thelma Sanchez, Larisa Movina, Pedro Morgado, Sofia Brissos, Oleg Aizberg, Anna Mosina, Damir Krinitski, James Mugisha, Dena Sadeghi-Bahmani, Farshad Sheybani, Masoud Sadeghi, Samira Hadi, Serge Brand, Antonia Errazuriz, Nicolas Crossley, Dragana Ignjatovic Ristic, Carlos López-Jaramillo, Dimitris Efthymiou, Praveenlal Kuttichira, Roy Abraham Kallivayalil, Afzal Javed, Muhammad Iqbal Afridi, Bawo James, Omonefe Joy Seb-Akahomen, Jess Fiedorowicz, Jeff Daskalakis, Lakshmi N Yatham, Lin Yang, Tarek Okasha, Aïcha Dahdouh, Jari Tiihonen, Jae Il Shin, Jinhee Lee, Ahmed Mhalla, Lotfi Gaha, Takoua Brahim, Kuanysh Altynbekov, Nikolay Negay, Saltanat Nurmagambetova, Yasser Abu Jamei, Mark Weiser, Christoph U Correll

Faculty, Staff and Students Publications

International studies measuring wellbeing/multidimensional mental health before/ during the COVID-19 pandemic, including representative samples for >2 years, identifying risk groups and coping strategies are lacking. COH-FIT is an online, international, anonymous survey measuring changes in well-being (WHO-5) and a composite psychopathology P-score, and their associations with COVID-19 deaths/restrictions, 12 a-priori defined risk individual/cumulative factors, and coping strategies during COVID-19 pandemic (26/04/2020-26/06/2022) in 30 languages (representative, weighted non-representative, adults). T-test, χ2, penalized cubic splines, linear regression, correlation analyses were conducted. Analyzing 121,066/142,364 initiated surveys, WHO-5/P-score worsened intra-pandemic by 11.1±21.1/13.2±17.9 points (effect size d=0.50/0.60) (comparable results in representative/weighted non-probability samples). Persons with …

Infant-Derived Human Nasal Organoids Exhibit Relatively Increased Susceptibility, Epithelial Responses, And Cytotoxicity During Rsv Infection, Gina M Aloisio, Divya Nagaraj, Ashley M Murray, Emily M Schultz, Trevor Mcbride, Letisha Aideyan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Anubama Rajan, Amal Kambal, Hannah L Johnson, Elina Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula

Faculty, Staff and Students Publications

Background: Respiratory syncytial virus (RSV) causes significant morbidity and mortality, especially in young children. Why RSV infection in children is more severe compared to healthy adults is not fully understood.

Methods: We used ex-vivo human nasal organoid platforms from infants and adults to investigate the underlying mechanism of this disease disparity at the initial site of RSV replication, the nasal epithelium.

Results: Infant-derived human nasal organoid-air liquid interface (HNO-ALIs) lines were more susceptible to early RSV replication. Moreover, infant-derived HNO-ALIs elicited a statistically significant greater overall cytokine response, enhanced mucous production, and greater cellular damage compared to their adult counterparts. …

Sexual Orientation, Gender Identity And Virologic Failure Among People With Hiv: A Cohort Study In All Of Us Research Program, Fanghui Shi, Ruilie Cai, Buwei He, Xiaoming Li Ph.D., Xueying Yang Ph.D., Sharon Weissman, Bankole Olatosi Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Background: Sexual and gender minorities (SGMs) are at higher risk of HIV incidence compared to their heterosexual cisgender counterparts. Despite the high HIV disease burden among SGMs, there was limited data on whether they are at higher risk of virologic failure, which may lead to potential disease progression and increased transmission risk. The All of Us (AoU) Research Program, a national community-engaged program aiming to improve health and facilitate health equity in the United States by partnering with one million participants, provides a promising resource for identifying a diverse and large volunteer TGD cohort. Leveraging various data sources available through …

Understanding Patients’ Experiences During Transitions From One Electronic Health Record To Another: A Scoping Review, Alison M Cogan, Trenton M Haltom, Stephanie L Shimada, Jessica A Davila, Bryan P Mcginn, Gemmae M Fix

Faculty, Staff and Students Publications

Objectives: Identify existing research on impacts of transitions between electronic health record (EHR) systems on patients' healthcare experiences.

Methods: Scoping review. We searched MedLine, OVID, Embase, CINAHL, and PsycInfo databases for articles on patient experiences with EHR-to-EHR transitions.

Results: Three studies met inclusion criteria. All three used validated surveys to compare patient satisfaction with care pre- and post-transition. The surveys did not include specific questions about the EHR transition; one study focused on patient perceptions of provider computer use. Satisfaction levels initially decreased following EHR implementation, then returned to baseline between six and 15 months later in two of three …

Veterans' Experiences Of And Preferences For Patient-Centered, Measurement-Based Ptsd Care, Marcela C Weber, Ashlyn M Jendro, Ellen P Fischer, Karen L Drummond, Trenton M Haltom, Natalie E Hundt, Michael A Cucciare, Jeffrey M Pyne

Faculty, Staff and Students Publications

Background: Up to 50% of veterans drop out of trauma-focused evidence-based psychotherapies (TF-EBP) without completing treatment or recovering; evidence suggests this is in part because their posttraumatic stress disorder (PTSD) care is insufficiently patient-centered. There is also evidence that measurement-based care (MBC) for mental health should be personalized to the patient, yet this is not common practice in VA PTSD care.

Objectives: To explore veterans' experiences and preferences for aligning measurement-based PTSD care with their own treatment goals.

Method: Qualitative interviews were conducted with veterans (n=15) with PTSD who had received at least 2 sessions of a TF-EBP.

Measures: Survey …

Exploring Fibroblast Interactions On Nanocrystalline Surfaces In Physiological Environments Through A Phenomenological Lens, R D K Misra, Aladin M Boriek

Faculty, Staff and Students Publications

The cytological behaviour and functional dynamics (adhesion, spreading, synthesis of proteins) of fibroblasts when interacting with biomedical surfaces are intricately influenced by the inherent nature of surface (nanocrystalline or microcrystalline), where the nanocrystalline (NC) surface is preferred in relation to the microcrystalline (MC) surface. This preference is a direct consequence of the distinct differences in physical and chemical characteristics between NC and MC surfaces, which include crystal boundary bio-physical attributes, electron work function, surface energy, and charge carrier density. The observed variances in cytological behaviour at the interfaces of NC and MC bio-surfaces can be attributed to these fundamental differences, …

Bst2 Facilitates Activation Of Hematopoietic Stem Cells Through Erk Signaling, Marcus A Florez, Apoorva Thatavarty, Duy T Le, Holly A Hill, Youngjae Jeong, Brian M Ho, Pawel Kus, Trisha K Wathan, Bailee N Kain, Shixia Huang, Dongsu Park, Katherine Y King

Faculty, Staff and Students Publications

The proinflammatory cytokine interferon-gamma (IFNγ) is upregulated in a variety of infections and contributes to bone marrow failure through hematopoietic stem cell (HSC) activation and subsequent exhaustion. The cell surface protein, bone marrow stromal antigen 2 (BST2), is a key mediator of this process, as it is induced upon interferon stimulation and required for interferon-dependent HSC activation. To identify the mechanism by which BST2 promotes interferon-dependent HSC activation, we evaluated its role in niche localization, immune cell function, lipid raft formation, and intracellular signaling. Our studies indicated that knock out (KO) of BST2 in a murine model does not disrupt …

A New Ex Vivo Model System To Analyze Factors Affecting The Integrity Of Fetal Membranes In Fetoscopic Surgery, Serjosha Robmann, Raoul Hopf, Costanza Giampietro, Lukas Moser, Alexandra Dolder, Magdalena Sanz Cortes, Martin Ehrbar, Nicole Ochsenbein, Jan Deprest, Edoardo Mazza

Faculty, Staff and Students Publications

We developed an ex vivo model system to analyze the influence of relevant environmental and mechanical factors potentially affecting the integrity of fetal membranes during fetoscopic surgery. The set-up exposes amniochorion membranes to insufflation at predefined levels of gas pressure, flow, humidity, and temperature. Change in fetal membranes stiffness is quantified during the phase mimicking surgery through measurement of membranes' strain in response to cyclic overpressure. The trocar induced perforation creates a mechanical weakness whose stability is assessed by increasing the insufflation pressure until membrane rupture. Damage of the epithelial cells lining the amnion is assessed through live-dead staining. Initial …