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Articles 4801 - 4830 of 55609

Full-Text Articles in Public Health

Sex-Specific Astrocyte Regulation Of Spinal Motor Circuits By Nkx61, Navish A Bosquez Huerta, Zhung-Fu Lee, Eun-Ah Christine Song, Junsung Woo, Yi-Ting Cheng, Debosmita Sardar, Ozlem Sert, Ehson Maleki, Kwanha Yu, Ekin Su Akdemir, Kaitlyn Sanchez, Juyeon Jo, Matthew N Rasband, Hyun Kyoung Lee, Akdes Serin Harmanci, Benjamin Deneen Jan 2025

Sex-Specific Astrocyte Regulation Of Spinal Motor Circuits By Nkx61, Navish A Bosquez Huerta, Zhung-Fu Lee, Eun-Ah Christine Song, Junsung Woo, Yi-Ting Cheng, Debosmita Sardar, Ozlem Sert, Ehson Maleki, Kwanha Yu, Ekin Su Akdemir, Kaitlyn Sanchez, Juyeon Jo, Matthew N Rasband, Hyun Kyoung Lee, Akdes Serin Harmanci, Benjamin Deneen

Faculty, Staff and Students Publications

Astrocytes exhibit diverse cellular and molecular properties across the central nervous system (CNS). Recent studies identified region-specific transcription factors (TF) that oversee these diverse properties; how sex differences intersect with region-specific transcriptional programs to regulate astrocyte function is unknown. Here, we show that the TF Nkx6.1 is specifically expressed in ventral astrocytes of the spinal cord and that its deletion results in sex-specific effects on astrocyte morphology. Astrocytes from males exhibit enhanced morphological complexity, accompanied by increased motor function and cholinergic synapses. In contrast, female astrocytes exhibit reduced complexity and no changes in motor function. Mechanistically, we found that Nkx6.1 …


Understanding The Impacts Of Surgical Drains On Postoperative Pain And Quality Of Life, Goutam K. Gadiraju, Matthew R. Prospero, Finn Tobias, Andrew J. Malek, Erik Reiche, Justin M. Broyles Jan 2025

Understanding The Impacts Of Surgical Drains On Postoperative Pain And Quality Of Life, Goutam K. Gadiraju, Matthew R. Prospero, Finn Tobias, Andrew J. Malek, Erik Reiche, Justin M. Broyles

School of Medicine Faculty Publications

Background: Surgical drains are commonly used in breast surgery and breast reconstruction for seroma prevention. Although many surgeons are aware that surgical drains can cause considerable discomfort to patients, less is understood about the specific impacts of drains on postoperative pain and quality of life (QOL). Methods: A cross-sectional survey was conducted among patients at our institution who had previously undergone mastectomy or breast reconstruction procedures to better understand patients' experiences with surgical drains. Patients were asked to report their attitudes toward a series of QOL statements and rate postoperative pain using numeric pain scales. Pair-wise analysis was used to …


An Investigation Of Travel Distance And Timeliness Of Breast Cancer Treatment Among A Diverse Cohort In The United States, Swann Arp Adams, Oluwole Adeyemi Babatunde, Whitney Zahnd, Peiyin Hung, Karen E. Wickersham, Nathaniel Bell Ph.D., Jan M. Eberth Ph.D. Jan 2025

An Investigation Of Travel Distance And Timeliness Of Breast Cancer Treatment Among A Diverse Cohort In The United States, Swann Arp Adams, Oluwole Adeyemi Babatunde, Whitney Zahnd, Peiyin Hung, Karen E. Wickersham, Nathaniel Bell Ph.D., Jan M. Eberth Ph.D.

Publications

Travel to and from distant cancer treatment facilities can place a significant burden on cancer patients, particularly rural and minority survivors. Thus, the purpose of our investigation was to examine the association between patient travel distance and delays in types of treatment for breast cancer (surgery, radiation, chemotherapy, and hormonal therapy) and treatment delays. Using a novel linkage between the state cancer registry and administrative data from Medicaid and a private insurance plan, 2155 BC patients were successfully linked to create the cohort. ArcGIS was used to geocode all case residences and treatment facility addresses and calculate network distance between …


Analisis Faktor Risiko Distres Pada Petugas Kpps Di Tangerang Selatan: Studi Kasus Pemilu Tahun 2024, Puti Intan Sari, Dadan Erwandi Jan 2025

Analisis Faktor Risiko Distres Pada Petugas Kpps Di Tangerang Selatan: Studi Kasus Pemilu Tahun 2024, Puti Intan Sari, Dadan Erwandi

National Journal of Occupational Health and Safety

General elections or elections are processes for citizens to elect the president, vice president, and representatives directly. Elections are organized by various organizations or bodies, one of which is the polling station organizing group (KPPS). Based on studies, KPPS officers bear a heavy workload leading to distress among them. This research aims to analyze distress risk factors among KPPS officers in South Tangerang during the 2024 elections. The study uses a quantitative method with a cross-sectional study design. Data analysis involves descriptive and inferential statistics. The results show that 68.8% of the officers experience moderate stress, while 31.2% experience mild …


Kajian Risiko Kesehatan Pajanan Bahaya Kimia Benzene, Toluene, Dan Xylene Pada Pekerja Laboratorium Lubricant Pt X, Muhammad Reyhan Ahadin Pratama, Mila Tejamaya Jan 2025

Kajian Risiko Kesehatan Pajanan Bahaya Kimia Benzene, Toluene, Dan Xylene Pada Pekerja Laboratorium Lubricant Pt X, Muhammad Reyhan Ahadin Pratama, Mila Tejamaya

National Journal of Occupational Health and Safety

Lubricant laboratory pose various occupational safety and health hazards to their workers. Exposure to chemical hazards can occur through multiple routes and can lead to both acute and chronic health risks for laboratory workers. This study aims to analyze the health risks associated with exposure to benzene, toluene, and xylene (BTX) among lubricant laboratory workers at PT X. The study was conducted from February to June 2024 using a descriptive analytical research design with the chemical health risk assessment method from the Department of Safety and Health Malaysia (DOSH) 2018. Data collection techniques were employed quantitatively through personal exposure measurements …


Correlates Of Inaccuracy In Reporting Of Energy Intake Among Persons With Multiple Sclerosis, Stephanie L Silveira, Brenda Jeng, Barbara A Gower, Gary R Cutter, Robert W Motl Jan 2025

Correlates Of Inaccuracy In Reporting Of Energy Intake Among Persons With Multiple Sclerosis, Stephanie L Silveira, Brenda Jeng, Barbara A Gower, Gary R Cutter, Robert W Motl

Faculty, Staff and Student Publications

BACKGROUND/OBJECTIVES: Persons with multiple sclerosis (MS) are interested in diet as a second-line approach for disease management. This study examined potential variables that correlate with inaccuracy of self-reported energy intake (EI) in adults with MS.

METHODS: Twenty-eight participants completed two assessment appointments within a 14-day period that included a standard doubly labeled water (DLW) protocol for estimating total energy expenditure (TEE). The participants reported their EI using the Automated Self-Administered 24 h (ASA24) Dietary Assessment Tool. The primary variables of interest for explaining the discrepancy between TEE and ASA24 EI (i.e., inaccuracy) included cognition (processing speed, visuospatial memory, and verbal …


Analisis Implementasi Prosedur Keselamatan Distribusi Bbm: Studi Kasus Pt Pertamina Patra Niaga Fuel Terminal Jambi, Tiara Sebrina Afrianti, Hafiz Adli Ananda, Taufiq Ihsan Jan 2025

Analisis Implementasi Prosedur Keselamatan Distribusi Bbm: Studi Kasus Pt Pertamina Patra Niaga Fuel Terminal Jambi, Tiara Sebrina Afrianti, Hafiz Adli Ananda, Taufiq Ihsan

National Journal of Occupational Health and Safety

Distribution of fuel oil (FO) using tanker trucks is highly risky. Although PT Pertamina Patra Niaga has adopted the Tanker Truck Safety Management System, accidents still occur. This study aimed to evaluate the implementation of FO distribution safety procedures at PT Pertamina Patra Niaga Fuel Terminal Jambi. This study used a cross-sectional approach. Primary data were collected through direct observation of 50 tanker trucks, including the physical condition, completeness of documents, and driver behavior. Secondary data, such as accident and inspection reports, were also analyzed. Fishbone analysis was used to identify the root cause, and scoring was done to determine …


Analisis Gangguan Fungsi Paru Pada Pekerja Di Area Stockpile Pelabuhan Talang Duku Jambi Tahun 2024, Azurly Difi Fahrandis, Melda Yenni, Entianopa Entianopa Jan 2025

Analisis Gangguan Fungsi Paru Pada Pekerja Di Area Stockpile Pelabuhan Talang Duku Jambi Tahun 2024, Azurly Difi Fahrandis, Melda Yenni, Entianopa Entianopa

National Journal of Occupational Health and Safety

The International Labour Organization (ILO) reported in 2018 that 2.78 million workers die annually due to occupational accidents and work-related diseases. Approximately 2.4 million (86.3%) of these deaths are caused by work-related illnesses. Dust exposure in the work environment can lead to lung function disorders in workers. This study aims to analyze lung function disorders and their relationship with risk factors among workers in the Stockpile Area of Talang Duku Port, Jambi, in 2024. The research method is cross-sectional, with a sample of 38 workers using research instruments including spirometry, questionnaires, interviews, and observations. Results show that 84.2% of respondents …


Hubungan Konsentrasi Pm 2,5 Dengan Keluhan Gangguan Pernapasan Pada Pekerja Uji Mekanis Up Pkb Pulo Gadung, Armando Wijaya Tampubolon, Doni Hikmat Hikmat Ramdhan Jan 2025

Hubungan Konsentrasi Pm 2,5 Dengan Keluhan Gangguan Pernapasan Pada Pekerja Uji Mekanis Up Pkb Pulo Gadung, Armando Wijaya Tampubolon, Doni Hikmat Hikmat Ramdhan

National Journal of Occupational Health and Safety

Vehicle emissions including traffic and transportation emissions have become the largest source of particulates in many cities in various countries. Health problems due to particulates from motor vehicles can not only occur around the highway, but can also occur in industries that are in contact with motor vehicles. Under these conditions, researchers wanted to conduct a study at UP PKB Pulo Gadung to see the relationship between PM2.5 concentrations and complaints of respiratory problems. The study sample totaled 38 people, consisting of mechanical testers and FKM UI community members as a comparison sample. The average result of measurements taken …


Efektivitas Full Body Stretching Dan Edukasi Manual Handling Digital Terhadap Keluhan Musculoskeletal Disorders Pekerja Yantek, Nadia Rosalinda, Anita Sulistyorini, Marji Marji, Supriyadi Supriyadi, Tika Dwi Tama Jan 2025

Efektivitas Full Body Stretching Dan Edukasi Manual Handling Digital Terhadap Keluhan Musculoskeletal Disorders Pekerja Yantek, Nadia Rosalinda, Anita Sulistyorini, Marji Marji, Supriyadi Supriyadi, Tika Dwi Tama

National Journal of Occupational Health and Safety

Occupational Diseases (PAK) in the form of pain complaints in the skeletal system that cause the work process are called Musculoskeletal Disorders (MSDs). PT. PLN Yantek workers are at risk of experiencing MSDs complaints because the work is done manually and the work posture is less ergonomic. This study aimed to analyze the effect of implementing full-body stretch and digital-based manual handling education and to assess its effectiveness on MSDs. The study used a quasi-experimental method with a one-group pretest-posttest design involving 26 Yantek workers. The intervention was given at 10 meetings, MSDs complaints were measured using the Nordic Body …


Virginia Academy Of Sleep Medicine Position Statement On School Start Times In Virginia, Sean Hesselbacher, Mariana Szklo-Coxe, Sachin Relia, Jonathan Gellman, Nicole Mcintyre Jan 2025

Virginia Academy Of Sleep Medicine Position Statement On School Start Times In Virginia, Sean Hesselbacher, Mariana Szklo-Coxe, Sachin Relia, Jonathan Gellman, Nicole Mcintyre

Eastern Virginia Medical Journal

The VASM endorses the 2017 AASM position statement that middle and high schools should begin no earlier than 8:30 a.m. The existing and updated scientific literature repeatedly identifies the detrimental impact of early high school start times, and the benefits of delaying start times, on the safety and well-being of students in Virginia. The adverse effects of early school start times on Virginia’s students have been demonstrated, with regards to academic performance, mental health, and driving risks. Data published since the AASM position paper highlight these dangers further. Importantly, recent studies also demonstrate some of the benefits that can come …


Social, Racial, And Economic Disparities Affecting Outcomes Of Hypertensive Adolescents, Kanya Singhapakdi, Amelia Haydel, Marla Johnston, Shengping Yang, Tamara Bradford, Dedrick Moulton, Thomas R. Kimball Jan 2025

Social, Racial, And Economic Disparities Affecting Outcomes Of Hypertensive Adolescents, Kanya Singhapakdi, Amelia Haydel, Marla Johnston, Shengping Yang, Tamara Bradford, Dedrick Moulton, Thomas R. Kimball

School of Medicine Faculty Publications

Essential hypertension is one of the most common conditions managed in pediatric cardiology and can result in lasting deleterious effects on the cardiovascular system. Pediatric hypertension is so prevalent in the United States that it is often referred to as a public health challenge. Social determinants of health (SDH) are the cultural, economic, educational, healthcare accessibility, and political influences in the environment in which an individual is born or lives, all of which can affect that individual's overall health. This study investigated the impact of social determinants such as rurality, food insecurity, transportation challenges, minority status, income, and race on …


What Women Intercollegiate Coaches Say: Decision-Making Factors When Navigating Career Choices, Courtney Boucher, Nicole M. Lavoi Jan 2025

What Women Intercollegiate Coaches Say: Decision-Making Factors When Navigating Career Choices, Courtney Boucher, Nicole M. Lavoi

International Journal of Physical Activity and Health

To address misconceptions about the lack of women in sport coaching, factors influencing intercollegiate women coaches' career decisions, including their choices to leave positions, apply for new ones, and accept or deny job offers were explored. Utilizing a multi-level analysis underpinned by critical feminist theory, a comprehensive understanding of the systemic and structural barriers women coaches faced, as well as the strategies they employed to navigate their careers were illuminated. Key findings revealed that unequal pay, lack of administrative support, insufficient resources, and pervasive gender biases significantly impacted women's career choices. The importance of supportive workplace environments, flexible working conditions, …


The Caitlin Clark Effect: Illuminating Women’S Sport History, Shelley Lucas Jan 2025

The Caitlin Clark Effect: Illuminating Women’S Sport History, Shelley Lucas

International Journal of Physical Activity and Health

The Caitlin Clark Effect is a term that describes the impact of the University of Iowa basketball player on the popularity of women’s basketball, which occurred in conjunction with Clark’s record-breaking performances in 2023 and 2024, as well as the Iowa team’s successes in the NCAA championship tournament. While the Caitlin Clark Effect is associated with intense media attention, ticket sales, and viewership, it also illuminates significant and lesser-known aspects of women’s sport history, specifically media coverage, the Association of Intercollegiate Athletics for Women (AIAW), and the state of Iowa’s unique basketball heritage and ‘6-on-6’ basketball rules. The purpose of …


Benefits, Challenges, And Strategies For Increasing Women Coaches In Elite Sport: The Trail To Gold (T2g) Initiative In U.S. Cross-Country Skiing, Anika Anna Angriman, Lynda B. Ransdell, Shelley Lucas, Nicole Lavoi Jan 2025

Benefits, Challenges, And Strategies For Increasing Women Coaches In Elite Sport: The Trail To Gold (T2g) Initiative In U.S. Cross-Country Skiing, Anika Anna Angriman, Lynda B. Ransdell, Shelley Lucas, Nicole Lavoi

International Journal of Physical Activity and Health

Despite tremendous growth in sport participation of girls and women following Title IX in 1972, women’s participation as sport coaches did not follow the same trajectory. In fact, women remain significantly underrepresented in sport coaching. Research highlights ongoing barriers within the sport industry's patriarchal structure, and although strategies have been proposed to improve women’s representation, the lack of progress over the past two decades indicates limited effectiveness. A better approach is essential to address this issue across individual, interpersonal, organizational, and societal levels. The purpose of this study is to interview participants within the U.S. cross-country skiing program, Trail to …


Improper Fitting Personal Protective Clothing And Subsequent Countermeasures For Physical Conditioning In Female Firefighters: A Narrative Review, Katie Sell, Mark Abel, J. Jay Dawes, Megan Thompson, Annette Zapp, Ofra Pottorf, Lilly Bernardi, James Prendergast Jan 2025

Improper Fitting Personal Protective Clothing And Subsequent Countermeasures For Physical Conditioning In Female Firefighters: A Narrative Review, Katie Sell, Mark Abel, J. Jay Dawes, Megan Thompson, Annette Zapp, Ofra Pottorf, Lilly Bernardi, James Prendergast

International Journal of Physical Activity and Health

The purpose of this paper was to 1) use an explorative literature overview to identify issues related to ill-fitting clothing and occupational gear for female firefighters, and 2) use an inductive approach to develop generalizable recommendations for exercise professionals to utilize by identifying significant themes in published peer reviewed articles related to movement and injury risk. Research, including both qualitative and quantitative approaches, has shown that the majority of current personal protective clothing (PPC) and operational gear was developed to fit a limited array of male physiques. Consequently, the improper fit of PPC and gear has presented numerous concerns that, …


Impact Of A Light Volleyball Intervention Among Older Chinese Adult Women, Ka-Man Carman Leung, Paul Lee, Wing Sze Alice Lai, Yanan Zhao, Lynda Ransdell Jan 2025

Impact Of A Light Volleyball Intervention Among Older Chinese Adult Women, Ka-Man Carman Leung, Paul Lee, Wing Sze Alice Lai, Yanan Zhao, Lynda Ransdell

International Journal of Physical Activity and Health

Modified sports offer a strategic approach to promoting health in older adults. Light volleyball, which uses a larger, lighter ball than traditional volleyball, is more accessible for this population. This study investigated the effects of a 16-week light volleyball program on the functional fitness of older adults in Hong Kong. A total of 275 participants aged 60 years or older were recruited and randomly assigned to three groups: a light volleyball intervention group, a Tai Chi group, and a control group. Functional fitness was assessed at the pretest, posttest, and 6-month follow-up. Results revealed that the light volleyball group exhibited …


The Quic-Sp: A Spanish Language Tool Assessing Unpredictability In Early Life Is Linked To Physical And Mental Health, Sabrina R. Liu, Natasha A. Bailey, Sara Romero-González, Amy Moors, Belinda Campos, Elysia P. Davis, Laura M. Glynn Jan 2025

The Quic-Sp: A Spanish Language Tool Assessing Unpredictability In Early Life Is Linked To Physical And Mental Health, Sabrina R. Liu, Natasha A. Bailey, Sara Romero-González, Amy Moors, Belinda Campos, Elysia P. Davis, Laura M. Glynn

Psychology Faculty Articles and Research

Accumulating evidence indicates that unpredictable signals in early life represent a unique form of adverse childhood experiences (ACEs) associated with disrupted neurodevelopmental trajectories in children and adolescents. The Questionnaire of Unpredictability in Childhood (QUIC) was developed to assess early life unpredictability, encompassing social, emotional, and physical unpredictability in a child’s environment, and has been validated in three independent cohorts. However, the importance of identifying ACEs in diverse populations, including non-English speaking groups, necessitates translation of the QUIC. The current study aims to translate and validate a Spanish language version of the QUIC (QUIC-SP) and assess its associations with mental and …


Coronavirus Disease 2019 (Covid-19) Real World Data Infrastructure: A Big-Data Resource For Study Of The Impact Of Covid-19 In Patient Populations With Immunocompromising Conditions, James M. Crawford, Lynne Penberthy, Ligia A. Pinto, Keri N. Althoff, Magdalene M. Assimon, Oren Cohen, Laura Gillim, Tracy L. Hammonds, Shilpa Kapur, Harvey W. Kaufman, David Kwasny, Jean W. Liew, William A. Meyer 3rd, Shannon L. Reynolds, Cheryl B. Schleicher, Suki Subbiah, Catherine Theruviparampil, Zachary S. Wallace, Jeremy L. Warner, Suhyeon Yoon, Yonah C. Ziemba Jan 2025

Coronavirus Disease 2019 (Covid-19) Real World Data Infrastructure: A Big-Data Resource For Study Of The Impact Of Covid-19 In Patient Populations With Immunocompromising Conditions, James M. Crawford, Lynne Penberthy, Ligia A. Pinto, Keri N. Althoff, Magdalene M. Assimon, Oren Cohen, Laura Gillim, Tracy L. Hammonds, Shilpa Kapur, Harvey W. Kaufman, David Kwasny, Jean W. Liew, William A. Meyer 3rd, Shannon L. Reynolds, Cheryl B. Schleicher, Suki Subbiah, Catherine Theruviparampil, Zachary S. Wallace, Jeremy L. Warner, Suhyeon Yoon, Yonah C. Ziemba

School of Medicine Faculty Publications

Background. We developed a United States–based real-world data resource to better understand the continued impact of the coronavirus disease 2019 (COVID-19) pandemic on immunocompromised patients, who are typically underrepresented in prospective studies and clinical trials. Methods. The COVID-19 Real World Data infrastructure (CRWDi) was created by linking and harmonizing de-identified HealthVerity medical and pharmacy claims data from 1 December 2018 to 31 December 2023, with severe acute respiratory syndrome coronavirus 2 virologic and serologic laboratory data from major commercial laboratories and Northwell Health; COVID-19 vaccination data; and, for patients with cancer, 2010 to 2021 National Cancer Institute Surveillance, Epidemiology, and …


Social Determinants Of Occupational Injuries Among Us-Based Commercial Fishermen: A Systematic Review, Shannon Guillot-Wright, Leonard Kuan-Pei Wang, Bibiana Toro Figueira, Mary Overcash Jones, Ruhi Maredia, Nikhita Kichili Jan 2025

Social Determinants Of Occupational Injuries Among Us-Based Commercial Fishermen: A Systematic Review, Shannon Guillot-Wright, Leonard Kuan-Pei Wang, Bibiana Toro Figueira, Mary Overcash Jones, Ruhi Maredia, Nikhita Kichili

Faculty, Staff and Student Publications

BACKGROUND: Commercial fishing is a multibillion-dollar industry that supports job growth, small- to large- businesses, and port and city revenue. The commercial fishing industry continues to be one of the most dangerous in the US, with a fatality rate nearly 40 times higher than the national average. Dangers of the fishing industry are multi-faceted and include hazardous working conditions, strenuous labor, long work hours, and harsh weather. Moreover, a vast majority of fishermen suffer from economic insecurity, including safe and affordable housing and food insecurity.

METHODS: We followed the recommendations and standards set by the Campbell and Cochrane Equity Methods …


Addressing Barriers To Equitable Telehealth For Older Adults, Bruce Leff, Christine S. Ritchie, Kristin L. Rising, Kendell Cannon, Liane Wardlow Jan 2025

Addressing Barriers To Equitable Telehealth For Older Adults, Bruce Leff, Christine S. Ritchie, Kristin L. Rising, Kendell Cannon, Liane Wardlow

Jefferson Center for Connected Care Faculty Papers

No abstract provided.


Impact Of Primary Care Benefits On Healthcare Utilisation And Estimated Out-Of-Pocket Expenses In Urban, Rural And Remote Settings In The Philippines, Janelle Micaela S. Panganiban, Romelei Camiling-Alfonso, Josephine T. Sanchez, Regine Ynez H. De Mesa, Gillian Sandigan, Arianna Maever L. Amit, Mia P. Rey, Johanna Faye E. Lopez, Noleen Marie Fabian, Cara Lois T. Galingana, Nannette Bernal-Sundiang, Maria Rhodora N. Aquino, Chad Lester Lastrilla, Miguel Callo, Carol Stephanie Chua Tan-Lim, Leonila F. Dans, Jose Rafael A. Marfori, Ramon Pedro Paterno, Antonio L. Dans Jan 2025

Impact Of Primary Care Benefits On Healthcare Utilisation And Estimated Out-Of-Pocket Expenses In Urban, Rural And Remote Settings In The Philippines, Janelle Micaela S. Panganiban, Romelei Camiling-Alfonso, Josephine T. Sanchez, Regine Ynez H. De Mesa, Gillian Sandigan, Arianna Maever L. Amit, Mia P. Rey, Johanna Faye E. Lopez, Noleen Marie Fabian, Cara Lois T. Galingana, Nannette Bernal-Sundiang, Maria Rhodora N. Aquino, Chad Lester Lastrilla, Miguel Callo, Carol Stephanie Chua Tan-Lim, Leonila F. Dans, Jose Rafael A. Marfori, Ramon Pedro Paterno, Antonio L. Dans

Ateneo School of Medicine and Public Health Publications

Background

This study aimed to determine the effects of primary care interventions on healthcare utilisation and estimated out-of-pocket (OOP) expenses in selected urban, rural and remote settings in the Philippines.

Methodology

Context-specific measures relating to expanding healthcare provider networks, augmenting the health human workforce and subsidising transportation costs were implemented to strengthen primary care systems. In this study, two key outcomes were monitored: (1) monthly healthcare utilisation measured by the total number of outpatient consultations per site and (2) change in OOP expenses from baseline to endline within a 1 year study period.

Results

All sites had a positive trend …


Evaluating Efficiency In Laboratory Methods For Testing Sexual Assault Kits, Renee Mercer Jan 2025

Evaluating Efficiency In Laboratory Methods For Testing Sexual Assault Kits, Renee Mercer

D.U.Quark

Sexual assault kits (SAKs) are a collection of physical evidence from a sexual assault victim. SAK testing provides victims justice and helps prevent repeated crime through the addition of perpetrator DNA into criminal databases. With large numbers of SAKs being collected yearly, the limitations of common laboratory procedures and resources create a backlog of SAKs. For that reason, there is a need for more efficient testing. This review evaluates three different methods of testing throughout this process. Reverse Transcription Recombinase Polymerase Amplification and Proximity Ligation Real-Time Polymerase Chain Reaction confirms body fluid identification. The Loop-Mediated Isothermal Amplification Assay reaction amplifies …


Multicenter Prospective Pilot Study Identifying Thrombomodulin As A Potential Biomarker For Neurocognitive Outcomes In Immune Thrombotic Thrombocytopenic Purpura, Aaron B Boothby, Michael D Evans, Shangbin Yang, Senthil Sukumar, James G Scott, Deirdra R Terrell, Spero Cataland, Marshall Mazepa Jan 2025

Multicenter Prospective Pilot Study Identifying Thrombomodulin As A Potential Biomarker For Neurocognitive Outcomes In Immune Thrombotic Thrombocytopenic Purpura, Aaron B Boothby, Michael D Evans, Shangbin Yang, Senthil Sukumar, James G Scott, Deirdra R Terrell, Spero Cataland, Marshall Mazepa

Faculty, Staff and Students Publications

Background/Objectives: Immune thrombotic thrombocytopenic purpura (iTTP) is a rare, chronically relapsing disorder that causes life-threatening thrombotic microangiopathy. Many survivors in clinical remission show evidence of ongoing silent cerebral infarction and neurocognitive deficits. Prospective longitudinal studies of this population are needed to acquire a complete understanding of the mechanism behind this ongoing neurologic injury. We aimed to assess the feasibility of a multicenter prospective study of neuropsychological and cognitive function in iTTP survivors in remission and examine novel biomarkers.

Methods: We aimed to enroll 50 iTTP patients across three USTMA consortium sites between 2019 and 2022 in a 24-month …


Case Report On Endocrine Induced Paralysis - " Unraveling The Impact Of Thyrotoxicosis On Potassium Homeostasis.", Srujith Pullipudi, Basava Chethan, Srinath K. M, Savitha Vijayakumar, Meghna B.S. Jan 2025

Case Report On Endocrine Induced Paralysis - " Unraveling The Impact Of Thyrotoxicosis On Potassium Homeostasis.", Srujith Pullipudi, Basava Chethan, Srinath K. M, Savitha Vijayakumar, Meghna B.S.

Digital Journal of Clinical Medicine

Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism, marked by episodes of muscle weakness and hypokalaemia. Although it predominantly affects young Asian men, it can also occur in females and individuals from non-Asian ethnic groups. TPP is a treatable form of hypokalaemic periodic paralysis and can often be the first indication of thyrotoxicosis. Triggers such as a high-carbohydrate diet, strenuous exercise, emotional stress, and steroid use can provoke TPP attacks. During an acute episode, the key diagnostic indicators are hypokalaemia along with elevated levels of thyroxine (T4) and triiodothyronine (T3). Treatment consists of two phases: promptly correcting hypokalaemia …


Abortion Training In Family Medicine: A Post-Dobbs Examination, Innes Tounkel, Lauren Kasoff, Brittany Macdonald, Krys Foster, Allison Casola, Glen Atlas Jan 2025

Abortion Training In Family Medicine: A Post-Dobbs Examination, Innes Tounkel, Lauren Kasoff, Brittany Macdonald, Krys Foster, Allison Casola, Glen Atlas

Cooper Rowan Medical Journal

No abstract for this article type.


Geographic Disparities Impacting Oral Vaccine Performance: Observations And Future Directions, Rachel M Burke, Sasirekha Ramani, Julia Lynch, Laura V Cooper, Haeun Cho, Ananda S Bandyopadhyay, Carl D Kirkwood, A Duncan Steele, Gagandeep Kang Jan 2025

Geographic Disparities Impacting Oral Vaccine Performance: Observations And Future Directions, Rachel M Burke, Sasirekha Ramani, Julia Lynch, Laura V Cooper, Haeun Cho, Ananda S Bandyopadhyay, Carl D Kirkwood, A Duncan Steele, Gagandeep Kang

Faculty, Staff and Students Publications

Oral vaccines have several advantages compared with parenteral administration: they can be relatively cheap to produce in high quantities, easier to administer, and induce intestinal mucosal immunity that can protect against infection. These characteristics have led to successful use of oral vaccines against rotavirus, polio, and cholera. Unfortunately, oral vaccines for all three diseases have demonstrated lower performance in the highest-burden settings where they are most needed. Rotavirus vaccines are estimated to have >85% effectiveness against hospitalization in children < 12 months in countries with low child mortality, but only ~65% effectiveness in countries with high child mortality. Similarly, oral polio vaccines have lower immunogenicity in developing country settings compared with high-resource settings. Data are more limited for oral cholera vaccines, but suggest lower titers among children compared with adults, and, for some vaccines, lower efficacy in endemic settings compared with non-endemic settings. These disparities are likely multifactorial, and available evidence suggests a role for maternal factors (e.g. transplacental antibodies, breastmilk), host factors (e.g. genetic polymorphisms-with the best evidence for rotavirus-or previous infection), and environmental factors (e.g. gut microbiome, co-infections). Overall, these data highlight the rather ambiguous and often contradictory nature of evidence on factors affecting oral vaccine response, cautioning against broad extrapolation of outcomes based on one population or one vaccine type. Meaningful impact on performance of oral vaccines will likely only be possible with a suite of interventions, given the complex and multifactorial nature of the problem, and the degree to which contributing factors are intertwined.


Racial And Ethnic Disparities In Human Papillomavirus Vaccination Among Us-Born And Foreign-Born Adults Aged 18 To 26 Years In The United States, Itunu Sokale, Jane Montealegre, Ann O Amuta, Abiodun Oluyomi, Aaron P Thrift Jan 2025

Racial And Ethnic Disparities In Human Papillomavirus Vaccination Among Us-Born And Foreign-Born Adults Aged 18 To 26 Years In The United States, Itunu Sokale, Jane Montealegre, Ann O Amuta, Abiodun Oluyomi, Aaron P Thrift

Faculty, Staff and Students Publications

Background/objectives: Human papillomavirus (HPV) is linked to multiple cancers that can be prevented through vaccination. While the optimal age for vaccination is in childhood and adolescence, vaccination recommendations include adults through age 26 who missed childhood/adolescent vaccination. There are limited data about disparities among adults eligible for catch-up HPV vaccination. We conducted a comprehensive examination of HPV vaccination among US young adults, disaggregating the group by race/ethnicity and nativity status to identify subgroups that may require additional interventions.

Methods: We analyzed 2019 and 2022 data of individuals aged 18-26 years from the National Health Interview Survey. Generalized linear models using …


Comparative Outcomes Of Endovascular Vs. Surgical Treatment In Craniocervical Junction Dural Arteriovenous Fistulas: A Systematic Review And Meta-Analysis, Basel Musmar, Joanna Roy, Atakan Orscelik, Sravanthi Koduri, Spyridon Karadimas, Saman Sizdahkhani, Elias Atallah, Stavropoula Tjoumakaris, Michael Gooch, Hekmat Zarzour, Ritam Ghosh, Richard Schmidt, Robert Rosenwasser, Pascal Jabbour Jan 2025

Comparative Outcomes Of Endovascular Vs. Surgical Treatment In Craniocervical Junction Dural Arteriovenous Fistulas: A Systematic Review And Meta-Analysis, Basel Musmar, Joanna Roy, Atakan Orscelik, Sravanthi Koduri, Spyridon Karadimas, Saman Sizdahkhani, Elias Atallah, Stavropoula Tjoumakaris, Michael Gooch, Hekmat Zarzour, Ritam Ghosh, Richard Schmidt, Robert Rosenwasser, Pascal Jabbour

Department of Neurosurgery Faculty Papers

BACKGROUND: Craniocervical junction dural arteriovenous fistulas (CCJ-DAVFs) are rare and complex vascular malformations that are challenging to diagnose and treat. This study aims to compare surgical and endovascular treatments for CCJ-DAVFs through a systematic review and meta-analysis.

METHODS: A systematic review and meta-analysis was conducted according to the PRISMA guidelines. PubMed, Scopus, and Web of Science databases were searched from inception to July 2024.

RESULTS: Fifteen studies involving 266 patients were included. Of these, 143 (53.8 %) patients underwent surgical treatment alone and 123 (46.2 %) underwent endovascular treatment alone. In the surgical group, the complete obliteration rate at last …


Successful Application Of Craniosacral Therapy In A Case Of Self-Harming And Low Mood In A 13-Year-Old Female., Caro O’Neill, Angie Butterfield Jan 2025

Successful Application Of Craniosacral Therapy In A Case Of Self-Harming And Low Mood In A 13-Year-Old Female., Caro O’Neill, Angie Butterfield

Journal of Transformative Touch

This case reports on the effectiveness of CranioSacral Therapy (CST) for a 13-year-old female presenting with self-harming by cutting, self-starving and poor sleep. Seven treatments of 45 minutes each, over a period of 9 months between September 2023 and June 2024 took place and monthly treatments are still ongoing. An improvement in symptoms was recorded after the first treatment and over the period of the treatments the client did not self-harm or self-starve and her sleep improved. At the first session the client scored 24 with the Patient Health Questionnaire – 9 (PHQ-9); at the seventh session her score was …