Public Health Commons^™

Complete Genomic Characterization Of Global Pathogens Respiratory Syntical Virus And Human Norovirus Using Probe Based Capture Enrichment, Sravya V Bhamidipati, Anil Surathu, Hsu Chao, Daniel P Agustinho, Qin Xiang, Kavya Kottapalli, Abirami Santhanam, Zeineen Momin, Kimberly Walker, Vipin K Menon, George Weissenberger, Nathanael Emerick, Faria Mahjabeen, Qingchang Meng, Jianhong Hu, Richard Sucgang, David Henke, Fritz J Sedlazeck, Ziad M Khan, Ginger A Metcalf, Vasanthi Avadhanula, Pedro A Piedra, Sasirekha Ramani, Robert L Atmar, Mary K Estes, Joseph F Petrosino, Richard A Gibbs, Donna M Muzny, Sara Cregeen Javornik, Harsha Doddapaneni

Faculty, Staff and Students Publications

Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in children worldwide, while human noroviruses (HuNoV) are a leading cause of epidemic and sporadic acute gastroenteritis. Generating full-length genome sequences for these viruses is crucial for understanding viral diversity and tracking emerging variants. However, obtaining high-quality sequencing data is often challenging due to viral strain variability, quality, and low titers. Here, we present a set of comprehensive oligonucleotide probe sets designed from 1,570 RSV and 1,376 HuNoV isolate sequences in GenBank. Using these probe sets and a capture enrichment sequencing workflow, 85 RSV positive nasal swab …

Characterizing Long Covid Symptoms During Early Childhood., Rachel S. Gross, Tanayott Thaweethai, Amy L. Salisbury, Lawrence C. Kleinman, Sindhu Mohandas, Kyung E. Rhee, Jessica N. Snowden, Kelan G. Tantisira, David Warburton, John C. Wood, Patricia A. Kinser, Joshua D. Milner, Erika B. Rosenzweig, Katherine Irby, Valerie J. Flaherman, Elizabeth W. Karlson, Lori B. Chibnik, Deepti B. Pant, Aparna Krishnamoorthy, Richard Gallagher, Michelle F. Lamendola-Essel, Denise C. Hasson, Stuart D. Katz, Shonna Yin, Benard P. Dreyer, Frank Blancero, Megan Carmilani, K Coombs, Megan L. Fitzgerald, Rebecca J. Letts, Aimee K. Peddie, Judy L. Aschner, Andrew M. Atz, Dithi Banerjee, Amanda Bogie, Hulya Bukulmez, Katharine Clouser, Lesley A. Cottrell, Kelly Cowan, Viren A. D'Sa, Allen Dozor, Amy J. Elliott, E Vincent S. Faustino, Alexander G. Fiks, Sunanda Gaur, Maria L. Gennaro, Stewart Gordon, Uzma N. Hasan, Christina M. Hester, Alexander Hogan, Daniel S. Hsia, David C. Kaelber, Jessica S. Kosut, Sankaran Krishnan, Russell J. Mcculloh, Ian C. Michelow, Sheila M. Nolan, Carlos R. Oliveira, Lynn M. Olson, Wilson D. Pace, Paul Palumbo, Hengameh Raissy, Andy Reyes, Judith L. Ross, Juan C. Salazar, Rangaraj Selvarangan, Cheryl R. Stein, Michelle D. Stevenson, Ronald J. Teufel, Alan Werzberger, John M. Westfall, Kathleen Zani, William T. Zempsky, Emily Zimmerman, Marie-Abele C. Bind, James Chan, Zoe Guan, Richard E. Morse, Harrison T. Reeder, Torri D. Metz, Jane W. Newburger, Dongngan T. Truong, Andrea S. Foulkes, Melissa S. Stockwell, Recover-Pediatrics Consortium, Recover-Pediatrics Group Authors

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Recent studies have identified characteristic symptom patterns of long COVID (LC) in adults and children older than 5 years. However, LC remains poorly characterized in early childhood. This knowledge gap limits efforts to identify, care for, and prevent LC in this vulnerable population.

OBJECTIVES: To identify symptoms that had the greatest difference in frequency comparing children with a history of SARS-CoV-2 infection to those without, to identify differences in the types of symptoms by age group (infants/toddlers [0-2 years] vs preschool-aged children [3-5 years]), and to derive an index that can be used in research studies to identify young …

Developing Reference Plans For Evaluating Global Clinical Trials Credentialing And Psqa Systems, Fre'etta M D Brooks, Mohammad Hussein, Jessica Lye, Christopher L Nelson, Nakamura Mitsuhiro, Mallory C Glenn, Patricia Diez, Rushil Patel, Maddison Shaw, Ileana Silvestre Patallo, Miriam Barry, Catharine H Clark, Joerg Lehmann, Stephen F Kry

Faculty, Staff and Student Publications

Purpose: To develop a practical framework for creating a diverse set of validated reference plans (varying in complexity) and implement a workflow to introduce beam modeling, calibration, and delivery errors into the reference cohort to test and compare various dosimetry audit methodologies.

Methods: Sixteen IMRT and VMAT reference plans were created, using RayStation software, for four phantom geometries based on established credentialing cases from participating Global Harmonization Group (GHG) members. These reference plans were first validated in a multi-ion-chamber phantom. Nine dosimetric errors (perturbations) were introduced into the plans by modifying beam model and/or delivery parameters (MLC-offset, MLC-transmission, leaf-tip-width, PDD, …

Hyalinization-Based Pathologic Response And Immune Infiltration Following Neoadjuvant Radiotherapy With Or Without Immune-Checkpoint Blockade In Localized Undifferentiated Pleomorphic Sarcoma, R S Traweek, M Zoghbi, R Lazcano, B M Cope, A J Bishop, A Farooqi, D Mitra, A K Yoder, B A Guadagnolo, D R Ingram, K Wani, D Shamsutdinova, A J Lazar, W-L Wang, C P Scally, E Z Keung, K E Torres, K K Hunt, R Ratan, J A Livingston, M S Nakazawa, D M Araujo, S Patel, V Ravi, A P Conley, M A Zarzour, N Somaiah, C L Roland, E F Nassif Haddad

Faculty, Staff and Student Publications

BACKGROUND: Standard-of-care treatment of localized undifferentiated pleomorphic sarcoma (UPS) involves preoperative radiotherapy (RT) and surgery. Combination of RT with immune-checkpoint blockade (ICB) represents a promising new strategy.

METHODS: Our primary objective was to assess survival outcomes and pathologically documented response in patients receiving RT with or without ICB or chemotherapy.

RESULTS: In a retrospective cohort of 68 patients with primary or locally recurrent UPS who received neoadjuvant RT with or without ICB, the ICB group had greater tumor hyalinization than the non-ICB group (89% compared with 30%, P = 0.018). In the non-ICB group, 19/37 patients (51%) achieved hyalinization-based pathologic …

Chronic Illness Education 2025: Patient Education Resources For Women With Chronic Kidney Disease, Aiden Tang, Carolyn Nagengast, Faith Scott, Isaiah Delaney, Jonathan Hakim, Kandis Fox, Katie Webster, Mahmoud Saad

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources To Treat Seasonal Affective Disorder, Amanda Teschner, Ayonitemi Odukoya, Brooke Waldon, Joshua Spence, Katelynn Paluch, Marilyn Li, Mercylia Untono, Nina Agemy

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Holistic Approach To Hiv Treatment And Management, Aniela Crayton, Harvey Sharma, Jacob Saenz, Justin Iqal, Marie Clancy, Olivia Carlisle, Raphaela Varella, Tarun Bomma

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Promoting Lifestyle Changes To Manage Hypertension In Underserved Adult Populations, Gabriel Doree, Jenna Uhles, Kathryn Benninghoff, Magd Boutany, Omar Abdalla, Rhea Sehgal, Udodirim Nwosu, Yiannos Demetriou

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Building Healthy Habits: Preventative Strategies For Childhood Obesity, Alissa Ward, Cameron Craig, Chloe Sutlick, Gabrielle Henry, Isabelle Adams, Jerimiah Gumma, Omer Abdullah, Sami Zaidi

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources For Addressing Copd In The Veteran Population, Daniel Molnar, Tochi Mbagwu, Kiana Sechler, Lillian Centlivre, Noah Kos, Tomilola Oyasiji, Safia Haniya Yusuf

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Improving Access To Educational Resources And Health Outcomes For Diabetes, Ami Suresh, Conner Slotnick, Danielle Santoyo, Eric Mylfurry, Karen Abdelmalek, Martin Murad, Preston Parana, Urva Mehveen

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Persistent Obesity In A College Student: A Case For Investigating Endocrine Disruptors In Diet, Jake Mcgue, Jolyna Chiangong, Katarina Woldt, Mary-Ann Essak, Muiz Muqri, Nikhil Patel, Redi Gishto

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Exercise Initiatives To Improve Child Obesity, Alice Werynski, Ashley Simbafo, Diana Kernen, Koa Williams, Linda Beqaj, Noah Krepostman, Trevor Buck

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Improving Outcomes Of Hiv In Marginalized Populations, Aidan Bailey, Alexis Bowles, Ammar Chauhdri, Biola Makinde-Odusola, Dea Kanani, Keshav Sharma, Vasanth Palanisamy, Waffa Bakheet

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources To Improve Incidence Of Atherosclerotic Cardiovascular Disease, Anthony Kavanagh, Arianna Mcclellan, Asa Smith-Villegas, Djelika Kabore, Lina Shalaby, Tara Rahmani, Vyom Grover, Zackariah Farah

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Managing Hiv In Youth: A Case-Based Application Of The Expanded Chronic Care Model, Adam Kabbani, Ali Nasser, Emi Ueda-Martinez, Kristina Rizo, Mason Gardiner, Matthew Manson, Rachel Chee, Sydni Rosenfeld

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Addressing Adolescent Depression Through Community And Systems-Based Care, Anirudh Gopalam, Connor Genschaw, Don'aa Williams, Gerardo Rubio Monroy, Jennifer Nnadozie, Murray Meri, Tina Tripathi, Abdullah Mahmood

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Chronic Illness Strategies & Resources: Type 1 Diabetes In Adolescence, Christian Turner, Emmett Miller, Halle Jonassaint, Kristina Zheng, Mehr Bawa, Supreet Singh, Tracy Markray, Victor Tawansy

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources To Improve Kidney Disease In Adults, Alan Berkovitz, Alejandro Damian, Anthony Tundo, Haziq Latif-Jangda, Jared Poliskey, Kristen Bartow, Petra Johnson, Sophie Turner

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Empowering Families With Resources To Combat Childhood Obesity, Abisola Fasakin, Alqasim Elnaggar, David Abdelnour, Mujeebah Kamal-Muili, Prit Patel, Ryan Palazzolo, Sydney Huston

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Lupus And Cardiovascular Disease Risk, Ahmad Almaat, Dina Bayachou, Halle Escher, Isabella Imirowicz, Myles Perry, Sherley Pagan Figueroa, Usman Siddiqui

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Pediatric Depression And Anxiety: Hope Through Healthcare, Andreas Mozny, Arjan Goenaga Castillo, Audrey Millar, Ebony Williams, Griffin Lotze, Haytham Al-Qasmi, Kamontip Jongnarangsin, Tricia Jain

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Improving Lifestyle Choices In Children Withtype-2 Diabetes Mellitus, David Williams, Hariharan Ramakrishnan, Luv Thakkar, Sanjana Kumar, Srikar Munukutla, Stephan Gonzalez, Taqwa Naas, Ted Hirschfield

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources To Improve Diabetes Mellitus In Adult Males, Abdul Naser Zamzami, David Echeverri, Isabella Costa, Musaed Al Rashidi, Pooja Menon, Xiaohan Zhan, Zain Abdun-Noor

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Improving The Understanding Of The Complexities Underlying Adult Obesity, Ethan Montoya, Maria Villalba, Morzouk Lawal, Nataliah Jwaida, Safa Razvi, Susan Lagrand, Vittal Ashwin Kandukuri, Robert Chalhoub

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Mitigation Of Cardiovascular Disease Risk Factors For Older Adults, Amber Hool, Benjamin Sun, Jacob Nielsen, Kevin Marzolf, Mariel Agbim, Nathan Beshai, Yusuf Hashem, Zahraa Ghosn

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Lifestyle Modification Resources For Cardiovascular Disease Risk Reduction, Ali Mustapha, Cheyenne Gonzales, Clara Devota, Emily Yao, Mahmood Alsughayer, Marcel Addis Jackson, Namrata Vedagarbha, Shane Tinsley

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Resources To Prevent Adolescent Hypertension, Anabelle Dally, Carlton Parker, Henry Ubaydi, Isabella Garcia, Joshua Mathews, Lila Tudrick, Michelle Brown, Ralph Durgham

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Barriers To Effective Diabetes Management In A Socioeconomically Disadvantaged Setting, Amaris Bradley, Karen Nakhla, Kyle Tsutsui, Mohamad Fardous, Saihaj Deol, William Frazier, Yeganeh Tabatabaei Alavi, Zackary Taylor

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Treatment, Resources, And Prevalence Of Depression Among Adolescents With Chronic Health Conditions, Daeho Kim, Elyse Vanderwoude, Francesca Settineri, James Moss, Karen Crile, Matthew Mellor, Rachele Willard, Sarah Farhat

Patient Education Projects

No abstract provided.