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Full-Text Articles in Public Health

Applying The Health Justice Framework To Address Health And Health Care Inequities Experienced By People With Disabilities During And After Covid-19, Robyn M. Powell Mar 2021

Applying The Health Justice Framework To Address Health And Health Care Inequities Experienced By People With Disabilities During And After Covid-19, Robyn M. Powell

Washington Law Review

The COVID-19 pandemic has been especially devastating for people with disabilities, as well as other socially marginalized communities. Indeed, an emerging body of scholarship has revealed that people with disabilities are experiencing striking disparities. In particular, scholars have shined a light on state and hospital triage policies that allow hospitals to ration critical health care and resources, such as ventilators, for people with disabilities if resources become limited and they cannot treat all patients during the pandemic. These injustices deserve extensive consideration from policymakers, legal professionals, and scholars.

Elucidating how the inequities that people with disabilities experience during the COVID-19 …


Exploring Parent Perception Of Adverse Childhood Experiences Screening In Pediatric Primary Care: A Clinical Inquiry Project, Kathryn Stevens Mar 2021

Exploring Parent Perception Of Adverse Childhood Experiences Screening In Pediatric Primary Care: A Clinical Inquiry Project, Kathryn Stevens

The Eleanor Mann School of Nursing DNP Capstone Projects

This manuscript explores the incidence and implications of Adverse Childhood Experiences (ACEs) and outlines a project assessing parental perception of their own ACEs screening during their child’s wellness visit. ACEs are adversarial events occurring during childhood, which may be chronic or singular. Abuse, neglect, and household dysfunction result in negative outcomes, including compromised neurological development and cognitive behaviors, developmental delays, poor lifestyle choices, and reduced mental and physical health. Additionally, a growing body of literature supports the impaired parenting skills in those with a history of ACEs. This can perpetuate intergenerational trauma, deprived opportunities, and poor familial health. Despite the …


Race And Ethnicity, Gender, And Age On Perceived Threats And Fear Of Covid-19: Evidence From Two National Data Sources, Michael D. Niño, Casey Harris, Grant Drawve, Kevin M. Fitzpatrick Mar 2021

Race And Ethnicity, Gender, And Age On Perceived Threats And Fear Of Covid-19: Evidence From Two National Data Sources, Michael D. Niño, Casey Harris, Grant Drawve, Kevin M. Fitzpatrick

Sociology and Criminology Faculty Publications and Presentations

Previous studies find preventative behaviors designed to reduce the number of infections during emerging disease outbreaks are associated with perceived risk of disease susceptibility. Few studies have attempted to identify underlying factors that explain differences in perceptions of risk during an infectious disease outbreak. Drawing from two early waves of American Trends Panel (n=7,441), as well as a National Science Foundation funded, Qualtrics national panel survey from the early stages of the pandemic (n=10,368), we test whether race and ethnicity, gender, and age were associated with six perceived threat and fear outcomes related to COVID-19. Results …


Predictive Modeling And Estimation Of The Doubling Time Of Confirmed Cases Of Covid-19 In Niger, Ibrahim Sidi Zakari, Hadiza Galadima Mar 2021

Predictive Modeling And Estimation Of The Doubling Time Of Confirmed Cases Of Covid-19 In Niger, Ibrahim Sidi Zakari, Hadiza Galadima

Community & Environmental Health Faculty Publications

Modeling is increasingly used to assess scenarios and make projections on the future course of new coronavirus disease. This allows for better planning of care as well as a relaxation or tightening of the restrictive measures decreed by the government and the health authorities. The data analyzed in this study covers the period from March 19 to June 05, 2020 and allowed predictions of new cases of COVID-19 based on a growth model with a growth rate that changes linearly over time. In addition, we calculated and predicted the doubling time of the number of positive cases in each region …


A Coupled Hazard Simulation And Post-Disaster Resource Optimization Framework, Stephen M. Cunningham Mar 2021

A Coupled Hazard Simulation And Post-Disaster Resource Optimization Framework, Stephen M. Cunningham

Theses and Dissertations

Extreme events, such as natural or human-caused disasters, cause mental health stress in affected communities. While the severity of these outcomes varies based on socioeconomic standing, age group, and degree of exposure, disaster planners can mitigate potential stress-induced mental health outcomes by assessing early, intermediate, and long-term treatment interventions by social workers and psychologists. However, local and state authorities are typically underfunded, understaffed, and have ongoing health and social service obligations that constrain mitigation and response activities. A resource assignment framework is developed as a coupled-state transition and linear optimization model that assists planners in optimally allocating constrained resources and …


Adolescent Access To Firearms-This Is Definitely Our Lane., Shayla Sullivant, M Denise Dowd Mar 2021

Adolescent Access To Firearms-This Is Definitely Our Lane., Shayla Sullivant, M Denise Dowd

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.


Association Between Preterm-Birth Phenotypes And Differential Morbidity, Growth, And Neurodevelopment At Age 2 Years: Results From The Interbio-21st Newborn Study, Jose Villar, María C. Restrepo-Méndez, Rose Mcgready, Fernando C. Barros, Cesar G. Victora, Shama Munim, Aris T. Papageorghiou, Roseline Ochieng, Rachel Craik, Zulfiqar Ahmed Bhutta Mar 2021

Association Between Preterm-Birth Phenotypes And Differential Morbidity, Growth, And Neurodevelopment At Age 2 Years: Results From The Interbio-21st Newborn Study, Jose Villar, María C. Restrepo-Méndez, Rose Mcgready, Fernando C. Barros, Cesar G. Victora, Shama Munim, Aris T. Papageorghiou, Roseline Ochieng, Rachel Craik, Zulfiqar Ahmed Bhutta

Department of Obstetrics & Gynaecology

Importance: The etiologic complexities of preterm birth remain inadequately understood, which may impede the development of better preventative and treatment measures.
Objective: To examine the association between specific preterm-birth phenotypes and clinical, growth, and neurodevelopmental differences among preterm newborns compared with term newborns up to age 2 years.
Design, setting, and participants: The INTERBIO-21st study included a cohort of preterm and term newborn singletons enrolled between March 2012 and June 2018 from maternity hospitals in 6 countries worldwide who were followed up from birth to age 2 years. All pregnancies were dated by ultrasonography. Data were analyzed from November 2019 …


Covid-19 Pandemic And Breast Cancer Management: A Retrospective Observational Clinical Study From Pakistan, Lubna Mushtaque Vohra, Dua Jabeen, Narmeen Asif, Abdul Ahad Mar 2021

Covid-19 Pandemic And Breast Cancer Management: A Retrospective Observational Clinical Study From Pakistan, Lubna Mushtaque Vohra, Dua Jabeen, Narmeen Asif, Abdul Ahad

Section of General Surgery

Background: COVID-19 outbreak has adversely affected care of breast cancer patients world-wide. There is paucity of available data on cancer management in lower-middle income countries during this pandemic, we sought to determine the institutional approach towards management of breast cancer patients and the outcomes during COVID-19 pandemic at our institution.
Materials and methods: Clinicopathological and treatment record of cancer patients who presented to the Breast Clinic from 15th March to 31st December 2020 was retrieved from the institutional database for this retrospective clinical observational study.
Results: A total of 292 patients were qualified for the analysis in which 206 …


Detection Of Mutations Associated With Variants Of Concern Via High Throughput 2 Sequencing Of Sars-Cov-2 Isolated From Nyc Wastewater, Davida S. Smyth, Monica Trujillo, Kristen Cheung, Anna Gao, Irene Hoxie, Sherin Kannoly, Nanami Kubota, Michelle Markman, Kaung Myat San, Geena Sompanya, John J. Dennehy Mar 2021

Detection Of Mutations Associated With Variants Of Concern Via High Throughput 2 Sequencing Of Sars-Cov-2 Isolated From Nyc Wastewater, Davida S. Smyth, Monica Trujillo, Kristen Cheung, Anna Gao, Irene Hoxie, Sherin Kannoly, Nanami Kubota, Michelle Markman, Kaung Myat San, Geena Sompanya, John J. Dennehy

Publications and Research

Monitoring SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection may lead to the emergence of novel variants resistant to naturally acquired or vaccine-induced immunity. To date, most data on SARS-CoV-2 genetic diversity has come from the sequencing of clinical samples, but such studies may suffer limitations due to costs and throughput. Wastewater-based epidemiology may provide an alternative and complementary approach for monitoring communities for novel variants. Given that SARS-CoV-2 can infect the cells of the human gut and is found in high concentrations in feces, wastewater may be a valuable source of SARS-CoV-2 RNA, which can be deep sequenced …


Persistent Post-Surgical Pain Following Breast Cancer Surgery: An Observational Study In A Tertiary Care Hospital, Ali Sarfraz Siddiqui, Sana Zeeshan, Aliya Ahmed, Shaista Khan Mar 2021

Persistent Post-Surgical Pain Following Breast Cancer Surgery: An Observational Study In A Tertiary Care Hospital, Ali Sarfraz Siddiqui, Sana Zeeshan, Aliya Ahmed, Shaista Khan

Department of Anaesthesia

Objective: To determine the frequency of persistent pain in patients after breast cancer surgery, and to assess the distribution and characteristics of pain in such patients.
Methods: The prospective observational single cohort study was conducted at the Department of Anaesthesiology and in the Breast Clinic of the Department of Surgery, Aga Khan University Hospital, Karachi, from August 2016 to January 2017, and comprised adult female patients with biopsy-proven carcinoma of breast who were scheduled for elective definitive breast cancer surgery. The patients were followed up for up to three months post-surgery and those with persistent pain were followed up for …


Elaborating The Science Of Food Choice For Rapidly Changing Food Systems In Low-And Middle-Income Countries, Christine E. Blake Ph.D., Rd, Edward A. Frongillo Jr. Ph.D., Andrea M. Warren, Shilpa V. Constantinides, Krystal K. Rampalli, Shiva Bhandari Mar 2021

Elaborating The Science Of Food Choice For Rapidly Changing Food Systems In Low-And Middle-Income Countries, Christine E. Blake Ph.D., Rd, Edward A. Frongillo Jr. Ph.D., Andrea M. Warren, Shilpa V. Constantinides, Krystal K. Rampalli, Shiva Bhandari

Faculty Publications

The world’s food systems and environments have been changing dramatically, concomitant with changes in overand undernutrition. We elaborate the science of food choice to better understand, analyze, and respond to relationships between changing food environments and food choice. The science of food choice is concerned with generating knowledge about causal drivers of food choice decision making processes and behavior within immediate food and social environments. Three fundamental and interconnected questions undergird this science; 1) what do people eat from the options available and accessible?; 2) how do people interact with food environments?; and 3) why do people decide to acquire, …


Anti-Democratic Lessons From The Covid-19 Pandemic? Deweyan-Confucian Reflections On Democratic Aspirations In East Asia, Sor-Hoon Tan Mar 2021

Anti-Democratic Lessons From The Covid-19 Pandemic? Deweyan-Confucian Reflections On Democratic Aspirations In East Asia, Sor-Hoon Tan

Research Collection School of Social Sciences

The election of Donald trump, Brexit and the drift towards authoritarianism of several third wave democracies raise questions and doubts about democracy. Some may see the pandemic having a further dampening effect on democratic aspirations in East Asia, this article argues that the mixed lessons of the pandemic suggest that East Asia would benefit from more, not less, democracy. The democracy they need is not the form of de facto American liberal democracy, but democracy suited to the Confucian cultures of various East Asian societies, understood as Dewey’s idea of community.


Teaching Migration In A Year Of Pandemic, Yasmin Y. Ortiga Mar 2021

Teaching Migration In A Year Of Pandemic, Yasmin Y. Ortiga

Research Collection School of Social Sciences

In August 2020, I faced the ironic task of teaching a class on international migration in the midst of a pandemic that halted most forms of cross-border movement in the world.


Utility Of Multi-Theory Model (Mtm) To Explain The Intention For Pap Adherence In Newly Diagnosed Sleep Apnea Patients, Manoj Sharma, Anuj Chandra, Ryan Toth, Vinayak K. Nahar Mar 2021

Utility Of Multi-Theory Model (Mtm) To Explain The Intention For Pap Adherence In Newly Diagnosed Sleep Apnea Patients, Manoj Sharma, Anuj Chandra, Ryan Toth, Vinayak K. Nahar

School of Public Health Faculty Research

Purpose: The objective of this study was to assess the utility of a fourth-generation multi-theory model (MTM) in explaining the intention for initiation and sustenance of PAP adherence among newly diagnosed sleep apnea patients.
/="/">Patients and Methods: For this cross-sectional study, data were collected at a private sleep center located in the Southeastern United States. A total of 138 newly diagnosed patients with sleep apnea who had been prescribed PAP therapy completed a valid and reliable 41-item MTM instrument. Stepwise multiple regression modeling was conducted to assess MTM based explanatory variables of PAP adherence in this study sample.
/="/" …


Analyzing Student Experience On Group Work With The Application Of Different Group Allocation Approaches, An Yee Tan Mar 2021

Analyzing Student Experience On Group Work With The Application Of Different Group Allocation Approaches, An Yee Tan

Management and HR

Working as a group can be as challenging as working by oneself. Common issues like ineffective group work, unequal work contribution, and poor communication are believed to be the reasons why many students preferred to work individually. The purpose of this study is to understand if there is a disparity in student experience on group work by implementing different methods of group formation, which are, intentional group formation and random assignment. Topics around team well-being, team communication, and team effectiveness are the main focus of this study. The second emphasis of this study is students’ opinions on whether or not …


Associations Between Maternal Technology Use, Perceptions Of Infant Temperament, And Indicators Of Mother-To-Infant Attachment Quality, Shawnee Alvarez Guitierrez, Alison K. Ventura Mar 2021

Associations Between Maternal Technology Use, Perceptions Of Infant Temperament, And Indicators Of Mother-To-Infant Attachment Quality, Shawnee Alvarez Guitierrez, Alison K. Ventura

Kinesiology and Public Health

Background: Previous research suggests parents' use of technological devices, such as TV and mobile devices, within family contexts may decrease the quality of parent-child interactions. During early infancy, mothers report engaging with technological devices during infant feeding and care interactions, however, few studies have explored potential associations between maternal technology use and the quality of mother-to-infant attachment.

Aim: To examine associations between maternal technology use during mother-infant interactions and indicators of mother-to-infant attachment during early infancy.

Study design: Cross-sectional survey.

Methods: Mothers (n = 332) of infants aged 2 to 6 months were recruited via MTurk, a crowdsourcing platform, …


Mortalidad Por Infarto Agudo De Miocardio En Guatemala 2018: Patrones E Inequidades, Alejandro Cerón, Gila Goldstein Mar 2021

Mortalidad Por Infarto Agudo De Miocardio En Guatemala 2018: Patrones E Inequidades, Alejandro Cerón, Gila Goldstein

Anthropology: Faculty Scholarship

El presente estudio busca analizar la mortalidad por infarto agudo de miocardio (IAM) en Guatemala con el propósito de identificar posibles criterios epidemiológicos que orienten la priorización de acciones de salud pública. El riesgo de morir de IAM en Guatemala muestra marcadas desigualdades por departamento, las que son aún más marcadas al comparar por municipio. El riesgo de morir es también más alto en personas mestizas o ladinas, en niveles educativos bajos, y en personas que se dedican a ocupaciones elementales. Deberían implementarse medidas de salud pública orientadas a los municipios y grupos en mayor riesgo de morir de IAM. …


Change In Outbreak Epicentre And Its Impact On The Importation Risks Of Covid-19 Progression: A Modelling Study, Oyelola A. Adegboye, Adeshina I. Adekunle, Anton Pak, Ezra Gayawan, Denis H. Y. Leung, Diana P. Rojas, Emma S. Mcbryde, Damon P. Eisen Mar 2021

Change In Outbreak Epicentre And Its Impact On The Importation Risks Of Covid-19 Progression: A Modelling Study, Oyelola A. Adegboye, Adeshina I. Adekunle, Anton Pak, Ezra Gayawan, Denis H. Y. Leung, Diana P. Rojas, Emma S. Mcbryde, Damon P. Eisen

Research Collection School Of Economics

Background: The outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) that was first detected in the city of Wuhan, China has now spread to every inhabitable continent, but now the attention has shifted from China to other epicentres. This study explored early assessment of the influence of spatial proximities and travel patterns from Italy on the further spread of SARS-CoV-2 worldwide. Methods: Using data on the number of confirmed cases of COVID-19 and air travel data between countries, we applied a stochastic meta-population model to estimate the global spread of COVID-19. Pearson's correlation, semi-variogram, and Moran's Index were used to …


The Association Between Overnight Fasting And Body Mass Index In Older Adults: The Interaction Between Duration And Timing, Qian Xiao, Cici Bauer, Tracy Layne, Mary Playdon Mar 2021

The Association Between Overnight Fasting And Body Mass Index In Older Adults: The Interaction Between Duration And Timing, Qian Xiao, Cici Bauer, Tracy Layne, Mary Playdon

Faculty, Staff and Student Publications

BACKGROUND: Circadian rhythms play an important role in the regulation of eating and fasting, and mistimed dietary intakes may be detrimental to metabolic health. Extended overnight fasting has been proposed as a strategy to better align the eating-fasting cycle with the internal circadian clock, and both observational and experimental studies have linked longer overnight fasting with lower body weight. However, it remains unclear if the timing of overnight fasting modifies the relationship between fasting duration and weight outcomes.

METHODS: The current study included 495 men and 499 women age 50-74 years. Dietary intake over 12 months was assessed by 24-h …


Incidence And Pathophysiology Of Diabetes In South Asian Adults Living In India And Pakistan Compared With Us Blacks And Whites, K M Venkat Naraya, Dimple Kondal, Natalie Daya, Unjali P. Gujral, Deepa Mohan, Shivani A. Patel, Roopa Shivashankar, Ranjit Mohan Anjana, Lisa R. Staimez, Muhammad Masood Kadir Mar 2021

Incidence And Pathophysiology Of Diabetes In South Asian Adults Living In India And Pakistan Compared With Us Blacks And Whites, K M Venkat Naraya, Dimple Kondal, Natalie Daya, Unjali P. Gujral, Deepa Mohan, Shivani A. Patel, Roopa Shivashankar, Ranjit Mohan Anjana, Lisa R. Staimez, Muhammad Masood Kadir

Community Health Sciences

Introduction: We compared diabetes incidence in South Asians aged ≥45 years in urban India (Chennai and Delhi) and Pakistan (Karachi), two low-income and middle-income countries undergoing rapid transition, with blacks and whites in the US, a high-income country.
Research design and methods: We computed age-specific, sex-specific and body mass index (BMI)-specific diabetes incidence from the prospective Center for Cardiometabolic Risk Reduction in South Asia Study (n=3136) and the Atherosclerosis Risk in Communities Study (blacks, n=3059; whites, n=9924). We assessed factors associated with incident diabetes using Cox proportional hazards regression.
Results: South Asians have lower BMI and waist circumference than blacks …


Re-Entry Housing Collaborative Final Evaluation Report, Monique Gill, Ritu Ghosal, Kyle Jones, Aisha K Gilmore Mar 2021

Re-Entry Housing Collaborative Final Evaluation Report, Monique Gill, Ritu Ghosal, Kyle Jones, Aisha K Gilmore

View All

No abstract provided.


Brain Candy: Wayne State University School Of Medicine Journal Of Arts And Culture, 8th Edition, Wayne State University School Of Medicine Gold Humanism Honor Society Mar 2021

Brain Candy: Wayne State University School Of Medicine Journal Of Arts And Culture, 8th Edition, Wayne State University School Of Medicine Gold Humanism Honor Society

Gold Humanism Honor Society

Brain Candy incorporates paintings, written pieces, and poetry from all the medical classes at Wayne State University School of Medicine to shed light on the creative process in medicine, the city of Detroit, and the experiences of health care providers. The first edition of Brain Candy was published online and in print in 2009, produced by a generous grant by the Gold Humanism Honor Society (GHHS). The edition featured poetry, nonfiction, short fiction, and different types of artwork. With generous funding support from alumnus Dr. Tom Janisse, Class of 1975, the journal continues to be in print since 2009.


Review Of Machine Learning Techniques For Mosquito Control In Urban Environments, Ananya Joshi, Clayton Miller Mar 2021

Review Of Machine Learning Techniques For Mosquito Control In Urban Environments, Ananya Joshi, Clayton Miller

Research Collection College of Integrative Studies

Machine learning (ML) techniques excel at forecasting, clustering, and classification tasks, making them valuable for various aspects of mosquito control. In this literature review, we selected 120 papers relevant to the current state of ML for mosquito control in urban settings. The reviewed work covers several different methodologies, objectives, and evaluation criteria from various environmental contexts. We first divided the existing papers into geospatial, visual, or audio categories. For each category, we analyzed the machine learning pipeline, from dataset creation to model performance. We conclude with a discussion of the challenges and opportunities for further research. While the reviewed ML …


The New Normal Of Social Psychology In The Face Of The Covid-19 Pandemic: Insights And Advice From Leaders In The Field, Kim Pong Tam, Angela K. Y. Leung, Sammyh Khan Mar 2021

The New Normal Of Social Psychology In The Face Of The Covid-19 Pandemic: Insights And Advice From Leaders In The Field, Kim Pong Tam, Angela K. Y. Leung, Sammyh Khan

Research Collection School of Social Sciences

Revisiting the history of social psychology, one noticeable trend is that the agenda of social psychologists is interwoven with events that happen in society and the world (Ross et al., 2010). For example, the Holocaust during World War II stimulated social psychologists’ interest in ethnocentrism, aggression, and obedience, just as increasing globalization became one of the impetuses for investigations into the role of culture in human behaviour, and hence the emergence of cultural and cross‐cultural psychology. Considering its immensity, we believe that the COVID‐19 pandemic will likely be a trigger for profound and consequential changes in social psychology (Khazaie & …


Assisted Reproductive Technologies And Health-Related Issues Among Women And Children: A Research Review, Laura Maria Corradi Mar 2021

Assisted Reproductive Technologies And Health-Related Issues Among Women And Children: A Research Review, Laura Maria Corradi

Dignity: A Journal of Analysis of Exploitation and Violence

From their first use in the late 1970s until the mid-1990s, Assisted Reproductive Technologies (ART) gave rise to serious concerns by feminists internationally. Their questions ranged from asking about health risks to ethical and political problems inherent in these technologies. However, over the last 25 years, interest in women’s health which used to be central to feminist theory and politics, progressively decreased and with it concerns about ART. Today, while the medical literature about health risks in ART is increasing, the topic of women’s health in relation to reproductive technologies remains marginal in feminist discourse, social sciences, and the mainstream …


Sars-Cov-2: Potencial Transmisión Feco-Oral E Implicaciones En La Propagación Y Gravedad Del Covid-19 En Venezuela. Mini-Revisión. [Sars-Cov-2: Potential Feco-Oral Transmission And Implications On The Spread And Severity Of Covid-19 In Venezuela. Mini-Review.], Leonor Chacin-Bonilla, Nathalie Chacon Mar 2021

Sars-Cov-2: Potencial Transmisión Feco-Oral E Implicaciones En La Propagación Y Gravedad Del Covid-19 En Venezuela. Mini-Revisión. [Sars-Cov-2: Potential Feco-Oral Transmission And Implications On The Spread And Severity Of Covid-19 In Venezuela. Mini-Review.], Leonor Chacin-Bonilla, Nathalie Chacon

School of Medicine Publications

The recognized human-to-human transmission of SARS-CoV-2 is through respiratory droplets and contact with contaminated surfaces. However, the high transmissibility of the virus and the pattern of symptoms of COVID-19 suggest the likelihood of other forms of spread. Increasing evidence suggests that SARS‐CoV‐2 could be transmitted by the feco‐oral route. SARS-CoV-2 is known to infect gastrointestinal epithelial cells and a significant number of infected people have gastrointestinal symptoms. Viable viruses, viral RNA, and prolonged shedding of viral RNA have been detected in the feces of COVID-19 patients. The virus has been found in sewage and surface waters of several countries. The …


Prevalence Of Covid-19 In Adolescents And Youth Compared With Older Adults In States Experiencing Surges, Barbara Rumain, Moshe Schneiderman, Allan Geliebter Mar 2021

Prevalence Of Covid-19 In Adolescents And Youth Compared With Older Adults In States Experiencing Surges, Barbara Rumain, Moshe Schneiderman, Allan Geliebter

Touro Scholarly Works

Purpose

There has been considerable controversy regarding susceptibility of adolescents (10–19 years) and youth (15–24 years) to COVID-19. However, a number of studies have reported that adolescents are significantly less susceptible than older adults. Summer 2020 provided an opportunity to examine data on prevalence since after months of lockdowns, with the easing of restrictions, people were mingling, leading to surges in cases.

Methods

We examined data from Departments of Health websites in six U.S. states experiencing surges in cases to determine prevalence of COVID-19, and two prevalence-related measures, in adolescents and youth as compared to older adults. The two other …


On The Application, Reporting, And Sharing Of In Silico Simulations For Genetic Studies, Kaleigh Riggs, Huann-Sheng Chen, Melissa Rotunno, Bing Li, Naoko I Simonds, Leah E Mechanic, Bo Peng Mar 2021

On The Application, Reporting, And Sharing Of In Silico Simulations For Genetic Studies, Kaleigh Riggs, Huann-Sheng Chen, Melissa Rotunno, Bing Li, Naoko I Simonds, Leah E Mechanic, Bo Peng

Faculty, Staff and Students Publications

In silico simulations play an indispensable role in the development and application of statistical models and methods for genetic studies. Simulation tools allow for the evaluation of methods and investigation of models in a controlled manner. With the growing popularity of evolutionary models and simulation-based statistical methods, genetic simulations have been applied to a wide variety of research disciplines such as population genetics, evolutionary genetics, genetic epidemiology, ecology, and conservation biology. In this review, we surveyed 1409 articles from five journals that publish on major application areas of genetic simulations. We identified 432 papers in which genetic simulations were used …


Is Covid-19-Induced Platelet Activation A Cause Of Concern For Patients With Cancer?, Lenard M Lichtenberger, K Vinod Vijayan Mar 2021

Is Covid-19-Induced Platelet Activation A Cause Of Concern For Patients With Cancer?, Lenard M Lichtenberger, K Vinod Vijayan

Faculty, Staff and Students Publications

Patients with cancer are more susceptible to be infected by SARS-CoV-2 and develop severe outcomes including ICU admittance, mechanical ventilator support, and a high rate of mortality. Like mid-to late-stage cancer, SARS-CoV-2 infection is associated with platelet hyperactivity, systemic inflammation, thrombotic complications, and coagulopathy. Platelets also promote cancer cell growth, survival in circulation, and angiogenesis at sites of metastases. In this article, we will discuss the potential for platelets in the development of systemic inflammation and thrombosis in SARS-CoV-2-infected patients with cancer, with the concern that the platelet-induced pathogenic events are likely magnified in cancer patients with COVID-19.


Will The Covid-19 Pandemic Finally Fuel Drug Repurposing Efforts?, Anna Chen, Shivangi Patel, Matthew Alcusky, Vittorio Maio Mar 2021

Will The Covid-19 Pandemic Finally Fuel Drug Repurposing Efforts?, Anna Chen, Shivangi Patel, Matthew Alcusky, Vittorio Maio

College of Population Health Faculty Papers

No abstract provided.