Psychiatry and Psychology Commons^™

Abnormal Involuntary Movement Scale In Tardive Dyskinesia: Minimal Clinically Important Difference, Martha Sajatovic

Faculty Scholarship

Background: A minimal clinically important difference has not been established for the Abnormal Involuntary Movement Scale in patients with tardive dyskinesia. Valbenazine is a vesicular monoamine transporter 2 inhibitor approved for the treatment of tardive dyskinesia in adults. Efficacy in randomized, double-blind, placebo-controlled trials was defined as the change from baseline in Abnormal Involuntary Movement Scale total score (sum of items 1-7). Objectives: To estimate an minimal clinically important difference for the Abnormal Involuntary Movement Scale using valbenazine trial data and an anchor-based method. Methods: Data were pooled from three 6-week double-blind, placebo-controlled trials: KINECT (NCT01688037), KINECT 2 (NCT01733121), and …

Buying-Shopping Disorder - Is There Enough Evidence To Support Its Inclusion In Icd-11?, Astrid Müller, Matthias Brand, Laurence Claes, Zsolt Demetrovics, Martina De Zwaan, Fernando Fernández-Aranda, Randy O. Frost, Susana Jimenez-Murcia, Michael Lejoyeux, Sabine Steins-Loeber, James E. Mitchell, Richard Moulding, Maja Nedeljkovic, Patrick Trotzke, Aviv Weinstein, Michael Kyrios

Psychology: Faculty Publications

The phenomenon of buying-shopping disorder (BSD) was described over 100 years ago. Definitions of BSD refer to extreme preoccupation with shopping and buying, to impulses to purchase that are experienced as irresistible, and to recurrent maladaptive buying excesses that lead to distress and impairments. Efforts to stop BSD episodes are unsuccessful, despite the awareness of repeated break-downs in self-regulation, experiences of post-purchase guilt and regret, comorbid psychiatric disorders, reduced quality of life, familial discord, work impairment, financial problems, and other negative consequences. A recent meta-analysis indicated an estimated point prevalence of BSD of 5%. In this narrative review, the authors …

The Effects Of Hand Holding On Cancer Patients Level Of Anxiety: A Single-Case Study, West Loveland

Graduate Theses and Dissertations

The purpose of this dissertation was to explore how the anxiety levels of non-Hodgkin’s lymphoma patients receiving chemotherapy are affected while holding hands with a secure attachment. This study utilized three experimental single-case designs: participant one measured under a B-design, participant two measured under a B-A design, and participant three measured under an A-B design. Each participant’s anxiety was assessed during six chemotherapy treatments and one meeting with their primary oncologist to discuss the prognosis of their cancerous disease. Results visually indicate a greater effect on anxiety reduction during treatment when the intervention is utilized compared to only having a …

A Controlled Examination Of Motivational Strategies: Reviewing Positive Consequences For Goal Achievement, Negative Consequences For Undesired Behavior, And A Relaxation Exercise, Yulia Gavrilova

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Motivation is an integral part of human life and one of the most fundamental aspects of behavior change. Of interest to the present study are two motivational approaches, Negative Consequences Review (NCR) and Positive Consequences Review (PCR). NCR is an intervention component originally designed as part of Family Behavior Therapy (FBT) to motivate individuals with their goals through a discussion of negative consequences associated with undesired behaviors. PCR was developed as an auxiliary component of FBT to inspire individuals’ motivation to achieve their goals through a discussion about positive consequences of reaching goals. Purpose: The purpose of this study …

The Basic Trait Of Antagonism: An Unfortunately Underappreciated Construct, Donald R. Lynam, Joshua D. Miller

Department of Psychological Sciences Faculty Publications

Antagonism, the low pole of Agreeableness, references traits related to immorality, combativeness, grandiosity, callousness, and distrustfulness. It is a robust correlate of externalizing behaviors such as antisocial behavior, aggression, and substance use; in fact, in many cases, it is the strongest trait correlate. It represents the core of many important and impactful psychopathological constructs (e.g., psychopathy, antisocial and narcissistic personality disorders). It is also central to models of general and disordered personality, psychopathology, and interpersonal behavior. As Neuroticism is core to understanding the intense distress and suffering that comes with internalizing disorders, Antagonism is core to understanding the impairment and …

Comorbidity Profile Of Head And Neck Cancer Patients With And Without Depression, Michaela Frenzel

Capstone Experience: Master of Public Health

This population-based retrospective study used SEER-Medicare data from 2002-2010 to assess depression, comorbidity, and substance use in the elderly head and neck cancer population. Out of 3,533 head and neck cancer patients, 10.6% had depression diagnoses two years prior to cancer diagnosis, 8.9% were newly diagnosed with depression within one year after cancer diagnosis, and 44.5% of those with preexisting depression had an additional depression diagnosis within one year following cancer diagnosis. Comorbid conditions (p<0.0001) and substance use (p=0.0017) showed associations with depression prior to cancer diagnosis yet, no significant associations with incidence of depression in this head and neck cancer population. This study affirms the need for continual depression screenings in head and neck cancer patients and suggests the need for increased research into the burden of comorbid conditions and substance use within the head and neck cancer population.

Reduced Gabaergic Signaling At The Axon Initial Segment Decreases Vigilance State Transitioning, Austin John Boren

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sleep is a highly regulated homeostatic process that is disrupted in an estimated 50-70 million Americans. Regulation of sleep depends upon coordinated signaling of multiple neurotransmitter systems. In particular, inhibitory gamma-aminobutyric acid (GABA) signaling is required to suppress wake-active brain regions in order to initiate and maintain sleep states. GABA type A receptors (GABAARs) are ionotropic receptors with subunit compositions uniquely enriched on subcellular domains of target cells. α2 subunit-containing GABAARs are the primary target of GABA released onto the axon initial segment (AIS), a site critical for phasing the oscillatory activity of cortical cells. α2-containing GABAARs have previously been …

Tattoo Narratives And Counseling, Danny Lane Mccarty

Graduate Theses and Dissertations

Much research has been done on tattoos and on those who acquire them, but most of the research has focused on negative correlations that might exist with people who have tattoos. This current research, however, showed that people’s tattoo narratives can relate to how they view self, others, and the world, and to how they approach life. A narrative approach to qualitative research was used, and ten people participated in the study. Participants’ views of self, others, and the world were discussed as these views emerged from the narratives. Their possible approaches to life were also addressed. Themes that emerged …

How Does Alcohol Intoxication Impair Risk Detection Of Sexual Assault? Testing An Integration Of Alcohol Myopia And Social Information Processing Theories, Alexander James Melkonian

Graduate Theses and Dissertations

Sexual assault among young adults is a highly prevalent public health concern. Alcohol is often implicated as a risk factor for sexual assault through its impairing effects on an individual’s ability to process and respond to social cues in the environment. The effect of alcohol myopia can result in greater focus of attention on salient environmental cues. The relationship between alcohol intoxication and resulting behavior may depend on what type of information is most salient. The current study examined the effects of alcohol on social information processing as it relates to sexual assault risk detection. Method: Participants were 48 young …

Dynamics Of Momentary Perceived Self-Regulation Abilities As Novel Predictors Of Overeating In Daily Life, Kayla Dawn Skinner

Graduate Theses and Dissertations

Despite an increase of research in the realm of overeating - a well-known contributor to obesity - the psychological mechanisms that maintain overeating behaviors across time and context are still poorly understood. It may be that people’s perceptions of their self-regulation abilities fluctuate over time, and overeating results from momentary increases in negative mood eliciting negative perceptions of their self-efficacy and current willpower, stronger beliefs that cravings can be controlled and a greater ability to tolerate distress. The current study examined the dynamics of and momentary predictors of overeating using a 7-day EMA protocol to study unsuccessful restrained eaters (n …

Implicit Bias And The Boundaries Of Belief: A Single-Representational Dual-Attitude Account Of Implicit Attitudes, Austin Dakota Synoground

Graduate Theses and Dissertations

Since their inception, implicit attitudes have been defined as associative mental states, separate from beliefs, which are considered to be propositional in nature. Recently, several philosophers have challenged this distinction, arguing that implicit attitudes are actually unconscious beliefs. In turn, I argue that the attitudes detected by current experimental paradigms are blind to distinctions between implicit attitudes, which I define as the products of an associative learning mechanism, and unconscious beliefs, which are the products of a propositional learning mechanism. Specifically, I argue for a single-representational dual-attitude account of implicit bias.

Individual Eeg Asymmetry As A Predictor Of Hydration Status During Exercise In The Heat, Ayano Katayama

Electronic Theses and Dissertations

Hydration behavior varies among individuals; continuous and correct fluid consumption behavior prevents decreased physical performance and severe dehydration, especially during extended exercise and hot environments. Therefore, the purpose of the present study was to examine individual frontal alpha electroencephalographic asymmetry index (FAI) score in eu-hydrated, hypo-hydrated, and exercise in well-trained men and assess if there is a correlation between FAI score and individual ad libitum fluid consumption behavior. Subjects were kinesiology major college students ranging from 21 to 29 years of age. Subjects were categorized either approach group (n = 8) with resting FAI score more than 0 or avoidance …

Role Of Naltrexone In Improving Compulsive Drinking In Psychogenic Polydipsia, Sukaina Rizvi, Jeffery Gold, Ali M. Khan

School of Medicine Publications

Psychogenic polydipsia or self-induced water intoxication is a potentially lethal condition seen in many chronic psychiatric patients. This is a literature review based on therapeutic significance of Naltrexone in improving compulsive water drinking behavior in chronic psychiatrically ill patients with psychogenic polydipsia. Naltrexone is an opioid antagonist approved by FDA for alcohol dependence. Extensive literature search provides a line of evidence that suggests correlation of opioid receptor with compulsive water ingestion in animals. However, there is limited data regarding clinical utility of naltrexone in improving psychogenic polydipsia in human species. This review highlights the necessity for further research and trials …

The Effectiveness Of Selective Serotonin Reuptake Inhibitors For Treatment Of Obsessive-Compulsive Disorder In Adolescents And Children: A Systematic Review And Meta-Analysis, Vijaya P. Kotapati, Ali M. Khan, Sara Dar, Gulshan Begum, Ramya Bachu, Mahwish Adnan, Aarij Zubair, Rizwan A. Ahmed

School of Medicine Publications

Background: Obsessive-compulsive disorder (OCD) is a common behavioral disorder among adolescents and children. The selective serotonin reuptake inhibitors (SSRIs) are the first pharmacological choice for this condition due to mild adverse effect profile.

Objective: This systematic review was performed to evaluate the efficacy of SSRI for OCD in adolescents and children.

Methods: Search terms were entered into PubMed, PsycINFO, Scopus, CINAHL, and Google Scholar. The included studies were randomized, placebo-controlled trials of SSRIs conducted in populations of children and adolescents younger than 18 years. Change from baseline Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), end-treatment CY-BOCS with respective SD, and response and …

Childhood Sexual Abuse: The Truth Behind The Trauma, Alexandra Punch

Population Health Research Brief Series

There are many misconceptions about coping behaviors, laws, and regulations that make coming forward difficult and painful. This issue brief discusses the hurdles for child victims of sexual assault and the initiatives taking place across the country to combat stereotypes and bring justice to children and their families.

A Letter To My Departed Niece, * Anonymous *

Journal of Patient-Centered Research and Reviews

The following piece was written in the weeks following the death of the author’s niece. It is an attempt to explore how we as a society handle health crises differently for medical versus mental health diagnoses.

Across Continents And Demographics, Unpredictable Maternal Signals Are Associated With Children's Cognitive Function, Elyssia Poggi Davis, Riikka Korja, Linnea Karlsson, Laura Glynn, Curt A. Sandman, Brian Vegetabile, Eeva-Leena Kataja, Saara Nolvi, Eija Sinervä, Juho Pelto, Hasse Karlsson, Hal S. Stern, Tallie Z. Baram

Psychology Faculty Articles and Research

Background

Early life experiences have persisting influence on brain function throughout life. Maternal signals constitute a primary source of early life experiences, and their quantity and quality during sensitive developmental periods exert enduring effects on cognitive function and emotional and social behaviors. Here we examined if, in addition to established qualitative dimensions of maternal behavior during her interactions with her infant and child, patterns of maternal signals may contribute to the maturation of children's executive functions. We focused primarily on effortful control, a potent predictor of mental health outcomes later in life.

Methods

In two independent prospective cohorts in Turku, …

Fire Safety Of Rectangular Hollow Section (Rhs) Truss Members With Local Imperfections, Luke Bailey

The Plymouth Student Scientist

This project investigates the effect of local imperfections on RHS truss members at elevated temperatures. The specific model used represents a realistic example of a RHS practical application and shows that local imperfections can have a detrimental effect on overall compressive resistance. Modelling showed that above 400C, a member with a local imperfection will experience global buckling and failure significantly quicker than a member without. In consequence, this paper concludes that all slender RHS members that are defined as a key element should be given suitable fire protection.

An Interpretative Phenomenological Analysis Investigating Uk Female Experiences Of Psychosocial Adjustment Following Bariatric Surgery, Mark J. Maxwell

The Qualitative Report

The psychosocial impact of bariatric surgery has not been studied as diligently as the physical impact, particularly within the first 6 months following surgery. The aim of the present study was to explore psychosocial adjustment in UK bariatric candidates within this time-scale. Six female participants were purposively recruited to complete a semi-structured interview, and Interpretative Phenomenological Analysis was used to analyse their experiences. Four super-ordinate themes emerged from the interview data which were: (1) "It was me but it wasn’t me": pre-surgery identity, (2) "I don’t see myself as this fat blob of a person anymore": transforming identity, (3) "No …

“I Don’T Want To Look Sick Skinny”: Perceptions Of Body Image And Weight Loss In Hispanics Living With Hiv In South Texas, Jordan W. Abel, Omar Allen, Delia Bullock, Erin Finley, Elizabeth Walter, Phillip Schnarrs, Barbara S. Taylor

Journal of Health Disparities Research and Practice

Objective: Obesity is rising in people with HIV (PLWH) and Hispanics. Both HIV and obesity are associated with cardiovascular disease morbidity and mortality. Our goal is to understand perceptions of body image and lifestyle in Hispanics with HIV to adapt interventions appropriately.

Methods: We conducted semi-structured interviews with 22 Hispanic PLWH and 6 providers. Purposive sampling selected patient participants across weights and genders. Interviews were coded and analyzed using grounded theory, comparing perspectives between patients with and without obesity, and patients and providers.

Results: Participants felt obesity and diabetes were “normal” in the community. Patients exhibited understanding of healthy diet …

Barriers To Epilepsy Care In Central Uganda, A Qualitative Interview And Focus Group Study Involving Plwe And Their Caregivers, Martha Sajatovic, Carol Blixen

Faculty Scholarship

Background: Epilepsy is a common neurological disease with substantial impact on the subject and their caretakers. This exploratory study identified barriers to care for persons living with epilepsy (PLWE) to develop a culturally acceptable nurse led self-management intervention for PLWE previously developed in the United States. Methods: The study involving 48 participants (31 PLWE and 17 caregivers) with in depth interviews and focus groups was conducted. We obtained insights into barriers to care in PLWE and their caregivers. Using a thematic analytic procedure emphasizing the dominant themes the qualitative responses were analyzed. Median age of PLWE was 24 years (IQR …

Distinct Patterns Of Default Mode And Executive Control Network Circuitry Contribute To Present And Future Executive Function In Older Adults, Christopher A. Brown, Frederick A. Schmitt, Charles D. Smith, Brian T. Gold

Neuroscience Faculty Publications

Executive function (EF) performance in older adults has been linked with functional and structural profiles within the executive control network (ECN) and default mode network (DMN), white matter hyperintensities (WMH) burden and levels of Alzheimer's disease (AD) pathology. Here, we simultaneously explored the unique contributions of these factors to baseline and longitudinal EF performance in older adults. Thirty-two cognitively normal (CN) older adults underwent neuropsychological testing at baseline and annually for three years. Neuroimaging and AD pathology measures were collected at baseline. Separate linear regression models were used to determine which of these variables predicted composite EF scores at baseline …

The Relationship Between Socioeconomic Status And White Matter Microstructure In Pre-Reading Children: A Longitudinal Investigation, Ola Ozernov-Palchik, Elizabeth S. Norton, Yingying Wang, Sara D. Beach, Jennifer Zuk, Maryanne Wolf, John D.E. Gabrieli, Nadine Gaab

Center for Brain, Biology, and Behavior: Faculty Publications

Reading is a learned skill crucial for educational attainment. Children from families of lower socioeconomic status (SES) tend to have poorer reading performance and this gap widens across years of schooling. Reading relies on the orchestration of multiple neural systems integrated via specific white-matter pathways, but there is limited understanding about whether these pathways relate differentially to reading performance depending on SES background. Kindergarten white-matter FA and second-grade reading outcomes were investigated in an SES-diverse sample of 125 children. The three left-hemisphere white-matter tracts most associated with reading, and their right-hemisphere homologs, were examined: arcuate fasciculus (AF), superior longitudinal fasciculus …

Getting Change-Space: A Grounded Theory Study Of Automated Ehealth Therapy, Marianne T. S. Holter, Ottar Ness, Ayna Johansen, Håvar Brendryen

The Qualitative Report

A promising tool for bettering people’s health is eHealth (or “mHealth”) programs: fully automated, web-based health interventions. However, we know surprisingly little about eHealth’s working mechanisms. One possible working mechanism is that program users benefit from a collaborative “relationship”—a “working alliance”—with the program. Although evidence support the existence of a person-to-program alliance it is unclear if and how it influences change. Therefore, we conducted a grounded theory study of how relating to an eHealth program for quitting smoking influenced the participants’ change processes. The ensuing model focuses on how participants got change-space—feeling free from social forcing and able to work …

Components Of The Triarchic Model Of Psychopathy Are Nested Within The Five-Factor Model, Courtland S. Hyatt, Donald R. Lynam, Joshua D. Miller

Department of Psychological Sciences Faculty Publications

The triarchic model of psychopathy is a recently developed model of psychopathy that identifies three primary domains: Boldness, Meanness, and Disinhibition. These traits overlap substantially with general and pathological five-factor model of personality (Boldness = low Neuroticism + high Extraversion; Meanness = low Agreeableness; Disinhibition = low Conscientiousness). In the current study (total N = 1,266), we compare domains from the triarchic model of psychopathy and five-factor model in relation to self- and informant-report of external criteria (e.g., pathological traits, antisocial behavior), and quantified their absolute similarity using a profile-matching approach. The corresponding traits from these models show large interrelations …

Identifying Depression In The National Health And Nutrition Examination Survey Data Using A Deep Learning Algorithm, Jihoon Oh, Kyongsik Yun, Uri Maoz, Tae-Suk Kim, Jeong-Ho Chae

Psychology Faculty Articles and Research

Background

As depression is the leading cause of disability worldwide, large-scale surveys have been conducted to establish the occurrence and risk factors of depression. However, accurately estimating epidemiological factors leading up to depression has remained challenging. Deep-learning algorithms can be applied to assess the factors leading up to prevalence and clinical manifestations of depression.

Methods

Customized deep-neural-network and machine-learning classifiers were assessed using survey data from 19,725 participants from the NHANES database (from 1999 through 2014) and 4949 from the South Korea NHANES (K-NHANES) database in 2014.

Results

A deep-learning algorithm showed area under the receiver operating characteristic curve (AUCs) …

Case Study: Effects Of Psychosocial Factors On A Geriatric Patient With Guillain Barré Syndrome, Keane Evangelista, Mary Pent Hunter, Jessica Phung, Aum Tejani, Lee Anne H. Robotta

San Marcos, Summer 2019

The purpose of this case report is to determine how a change in intrinsic motivation and environmental factors help physical and functional improvements in a 77-year-old male patient with Guillain Barré Syndrome (GBS) in the geriatric population. Interventions to promote this change included patient education about lifestyle choices along with endurance and balance exercises.

Patient psychological state, community access, and general education about interventions/dosing had an effect on the patient's participation in his prescribed HEP. His comorbidities hindered his overall progress over the course of his treatment and should be addressed to improve patient outcomes. Activities that were more salient …

Patterns Of Polysubstance Use Among Those With Tranquilizer Or Sedative Misuse: Predictors And Functional Consequences, Victoria R. Votaw

Psychology ETDs

The misuse of tranquilizer and sedative medications (i.e., use without a prescription or at higher doses/longer periods of time than prescribed) is associated with myriad negative sequalae, such as suicidal behaviors and increased risk of overdose. Yet, prescription tranquilizer and sedative misuse has been largely overlooked by the scientific community, clinicians, and policymakers. We addressed this gap in the literature by characterizing subgroups of individuals with tranquilizer or sedative misuse, based on their patterns of polysubstance use. The present study analyzed data from two samples of individuals with past-month tranquilizer or sedative misuse: respondents of a nationally-representative household survey (general …

An Examination Of The Triarchic Model Of Psychopathy's Nomological Network: A Meta-Analytic Review, Chelsea E. Sleep, Brandon Weiss, Donald R. Lynam, Joshua D. Miller

Department of Psychological Sciences Faculty Publications

Psychopathy is characterized by a constellation of traits including callousness, superficial charm, grandiosity, exploitativeness, irresponsibility, and impulsivity (e.g., Cleckley, 1941/1955; Hare, 2003). Despite longstanding interest, the nature and scope of the construct as well as the centrality and sufficiency of its components remain debated (i.e., Fearless Dominance/Boldness; Miller & Lynam, 2012; Lilienfeld et al., 2012). Recently, the Triarchic Model of Psychopathy (TriPM; Patrick, Fowles, & Krueger, 2009) has garnered considerable interest, positing that psychopathy can be characterized by three partially overlapping, phenotypic domains: Boldness, Meanness, and Disinhibition. The present meta-analysis sought to examine the relations between these domains and other …