Psychiatry and Psychology Commons^™

Examining The Evidence Base For Burnout, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

Burnout has elicited growing interest among occupational health specialists in recent decades. Since 2019, the World Health Organization has characterized burnout as a syndrome resulting from chronic, unmanageable workplace stress. According to the ICD-11, three symptoms define the entity: feelings of exhaustion, increased mental distance from one’s job, and a sense of ineffectiveness at work, all of which correspond to the structure of the Maslach Burnout Inventory. The ICD-11 includes burnout among the factors that influence health status. This paper calls into question that conceptualization based on a number of lines of evidence. The evidence includes the following: burnout was …

An Examination Of The Association Between Sleep Quality And Psychological Distress Among University Students In The Middle East: A Cross-Sectional Correlational Study, Ayesha Saeed Alsuwaidi

Theses

Literature reviews have revealed that there are limited studies on sleep quality in the United Arab Emirates (UAE) and that few studies are available in the Middle Eastern region. The objective of this study was to examine the association between sleep quality and psychological distress among university students in the Middle East. A correlational cross-sectional design was determined, and a self-administered online questionnaire was used. The electronic survey was circulated amongst students on campus and received 435 responses from three universities namely, Menoufia University in Egypt, Sultan Qaboos University in the Sultanate of Oman, and United Arab Emirates University in …

The Association Between Attachment Styles And Binge Eating Behaviours: Examination Of The Mediational Role Of Emotional Dysregulation In The Arab Region, Diala Kassab

Theses

Many factors are said to affect binge eating behaviours, one of these factors is the individual’s attachment style. Attachment styles is the early relationship that shape a child's ideas and expectations about themselves and the availability of other people. This can be mediated by the ability to effectively respond and manage emotional experiences. This thesis aimed to examine the role of emotional dysregulation on attachments styles and binge eating behaviours in the Arab region.
/="/">A sample of 326 Arab university students, predominantly Emirati and Lebanese, were recruited using convenience sampling and snowball sampling technique. Participants were asked to complete …

High Acceptability, Convenience And Reduced Carbon Emissions Of Tele-Neurology Outpatient Services At A Regional Referral Centre In Kenya, Fazal Yakub, Jasmit Shah, Dilraj Sokhi

Internal Medicine, East Africa

Background: There is severe shortage of neurologists in sub-Saharan Africa. Tele-neurology consultations (TNC) can bridge this service gap, but there is very little published evidence on TNC in our setting, which we addressed through our study.

Methods: We prospectively enrolled patients at our neurology outpatients from October 2020 to October 2021. We administered a post-TNC questionnaire which captured satisfaction/acceptability using Likert scales. A sub-group of participants who also did in-person consultations (IPC) were additionally administered post-IPC questionnaires. Statistical comparisons were made using the paired student t-test, and descriptive data expressed as median (inter-quartile range).

Results: From 219 enrolled patients, 66.7% …

Psychosocial Predictors Of Cosmetic Surgery Acceptance Among Young Adult Women In The Uae. The Role Of Selfie Behavior, Narcissism And Religiosity: A Cross-Sectional Study, Amna Ahmad Alsadani

Theses

Cosmetic surgery is prevalent in the UAE and has been linked to negative psychological and physical consequences. The present study investigates psychosocial factors expected to predict an acceptance of cosmetic surgery among young adult women in the UAE. It was hypothesized that high selfie behavior, high narcissism, and low levels of religiosity would have a positive association with an interest in cosmetic surgery. The factors that motivate people to undergo cosmetic surgery were assessed using the 15-item Acceptance of Cosmetic Surgery Scale. Selfie behavior was examined using two questions derived from previous research. Narcissism was assessed using the 16-item Narcissistic …

Examining The Parallel Mediating Effect Of Emotion Dysregulation And Eating Beliefs In The Association Between Low Self¬-Esteem And Binge Eating Behaviours, Farah Al Mohammed

Theses

Research in the United Arab Emirates (UAE) around the causes and non-pharmacological treatment options of binge eating behaviours and other eating disorders is limited. Moreover, given the documented increase in binge eating behaviours which, in turn, is associated with two additional eating disorders (i.e., binge eating disorder and bulimia nervosa), there is an urgent need to understand the factors that are implicated in the causation and maintenance of binge eating behaviours in the UAE. A comprehensive understanding of these factors will assist psychotherapists and other mental health professionals in tailoring the interventions that they provide in the treatment and management …

Mixed-Method Study Of Relationship Satisfaction Among African American Males With Or Without History Of Childhood Sexual Abuse, Sandra Webster Brown

Dissertations

Relationship satisfaction among African American males is an important and feasible topic and underrepresented among scholarly literature. The purpose of this study was to explore relationship satisfaction and experiences among African American males who may be impacted by history of childhood sexual abuse. The study was guided by the theoretical frameworks of family systems theory. Using a concurrent mixed-methods triangulation design, the researcher collected data quantitatively and qualitatively from an online survey. Data were collected from 43 African American males recruited from Black organizations in the United States. The qualitative data collected by written narratives from the men were used …

Regional Vulnerability Indices In Youth With Persistent And Distressing Psychoticlike Experiences, Nicole R Karcher, Hailey Modi, Peter Kochunov, Si Gao, Deanna M Barch

Faculty, Staff and Student Publications

IMPORTANCE: Distressing and persistent psychoticlike experiences (PLEs) in youth are associated with greater odds of developing psychiatric conditions in adulthood. Despite this risk, it is unclear whether early PLEs show similar brain patterns compared with adults with psychiatric and neurologic conditions.

OBJECTIVE: To examine the degree to which persistent and distressing PLEs exhibit neural metrics that show similarity to adults with chronic psychiatric and neurologic conditions.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study used Adolescent Brain Cognitive Development (ABCD) Study examining the persistence and distress associated with PLEs across the first 3 waves of data with baseline structural magnetic resonance …

Pancreatic Replacement Therapy For Maladaptive Behaviors In Preschool Children With Autism Spectrum Disorder, Deborah A Pearson, Robert L Hendren, Matthew F Heil, William R Mcintyre, Shane R Raines

Faculty, Staff and Student Publications

IMPORTANCE: There is an urgent unmet need for a treatment addressing the core symptoms and associated maladaptive symptoms of autism spectrum disorder (ASD), especially in preschool populations.

OBJECTIVES: To evaluate whether treatment of children with ASD aged 3 to 6 years treated with high-protease pancreatic therapy produces long- and short-term improvements in autism-associated maladaptive behaviors.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study at 32 sites across the US used a double-blind parallel group, delayed-start design comprising a 2-week blinded placebo run-in, and a double-blind, randomized, placebo-controlled segment (12 weeks). Children were recruited into the study in 2015, with data collection …

Risk Factors For Eating Disorders Among Uae University Students: The Role Of Family Dysfunction And Attachment Styles, Aya Jaber Dandachi

Theses

A topic that is highly researched nowadays in the UAE is eating disorders (EDs). They are characterized by a persistent disturbance of eating-related behaviors that can result in altered consumption of food. Literature has suggested that there are several factors that can make an individual vulnerable to EDs, including family dynamics and attachment styles. This thesis is an attempt to examine the impact of family dynamics and early attachment on mental health wellbeing. The main objective is to examine how family dysfunctional concepts (rigid, chaotic, enmeshed, and disengaged) and attachment styles (close, dependent, and anxious) can be potential risk factors …

Prevalence Of Sexual Desire And Arousal Difficulties Among Women Veterans: A Retrospective Cohort Design, Alexandra B Caloudas, Amber B Amspoker, Melinda Stanley, Derrecka Boykin, Kelley Arredondo, Annette Walder, Julianna Hogan, Jan A Lindsay

Faculty, Staff and Students Publications

Low sexual desire and arousal are associated with several negative health outcomes, including reduced quality of life, depression, anxiety, and relationship discord. Although women veterans have high rates of risk factors for sexual dysfunctions (e.g., elevated rates of trauma, depression, anxiety), research on their sexual functioning is lacking. Using a retrospective cohort design, we examined the prevalence of documented sexual desire and arousal disorder diagnoses or symptoms, using ICD-10 codes, among 790,726 women veterans receiving care in the Veterans Health Administration. In Fiscal Year 2020, these symptoms and disorders were documented for only 0.19% (n = 1,494) of women veterans …

Flow-Sizing Critical Care Resources, Joseph L Nates, John M Oropello, Neeraj Badjatia, Gregory Beilman, Craig M Coopersmith, Neil A Halpern, Daniel L Herr, Judith Jacobi, Roozehra Kahn, Sharon Leung, Nitin Puri, Ayan Sen, Stephen M Pastores

Staff and Researcher Publications

Objectives: To describe the factors affecting critical care capacity and how critical care organizations (CCOs) within academic centers in the U.S. flow-size critical care resources under normal operations, strain, and surge conditions.

Data sources: PubMed, federal agency and American Hospital Association reports, and previous CCO survey results were reviewed.

Study selection: Studies and reports of critical care bed capacity and utilization within CCOs and in the United States were selected.

Data extraction: The Academic Leaders in the Critical Care Medicine Task Force established regular conference calls to reach a consensus on the approach of CCOs to "flow-sizing" critical care services. …

Glut3 Promotes Macrophage Signaling And Function Via Ras-Mediated Endocytosis In Atopic Dermatitis And Wound Healing, Dong-Min Yu, Jiawei Zhao, Eunice E Lee, Dohun Kim, Ruchika Mahapatra, Elysha K Rose, Zhiwei Zhou, Calvin Hosler, Abdullah El Kurdi, Jun-Yong Choe, E Dale Abel, Gerta Hoxhaj, Kenneth D Westover, Raymond J Cho, Jeffrey B Cheng, Richard C Wang

Staff and Researcher Publications

The facilitative GLUT1 and GLUT3 hexose transporters are expressed abundantly in macrophages, but whether they have distinct functions remains unclear. We confirmed that GLUT1 expression increased after M1 polarization stimuli and found that GLUT3 expression increased after M2 stimulation in macrophages. Conditional deletion of Glut3 (LysM-Cre Glut3fl/fl) impaired M2 polarization of bone marrow-derived macrophages. Alternatively activated macrophages from the skin of patients with atopic dermatitis showed increased GLUT3 expression, and a calcipotriol-induced model of atopic dermatitis was rescued in LysM-Cre Glut3fl/fl mice. M2-like macrophages expressed GLUT3 in human wound tissues as assessed by transcriptomics and costaining, and GLUT3 expression was …

Structural Surfaceomics Reveals An Aml-Specific Conformation Of Integrin Β2 As A Car T Cellular Therapy Target, Kamal Mandal, Gianina Wicaksono, Clinton Yu, Jarrett J Adams, Michael R Hoopmann, William C Temple, Adila Izgutdina, Bonell Patiño Escobar, Maryna Gorelik, Christian H Ihling, Matthew A Nix, Akul Naik, William H Xie, Juwita Hübner, Lisa A Rollins, Sandy M Reid, Emilio Ramos, Corynn Kasap, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Melanie Mcmillan, Victor Gavallos, Andrew D Leavitt, Aaron C Logan, Cliona M Rooney, Justin Eyquem, Andrea Sinz, Benjamin J Huang, Elliot Stieglitz, Catherine C Smith, Robert L Moritz, Sachdev S Sidhu, Lan Huang, Arun P Wiita

Faculty, Staff and Students Publications

Safely expanding indications for cellular therapies has been challenging given a lack of highly cancer-specific surface markers. Here we explore the hypothesis that tumor cells express cancer-specific surface protein conformations that are invisible to standard target discovery pipelines evaluating gene or protein expression, and these conformations can be identified and immunotherapeutically targeted. We term this strategy integrating cross-linking mass spectrometry with glycoprotein surface capture ‘structural surfaceomics’. As a proof of principle, we apply this technology to acute myeloid leukemia (AML), a hematologic malignancy with dismal outcomes and no known optimal immunotherapy target. We identify the activated conformation of integrin β2 …

Racial And Ethnic Variation In Ecmo Utilization And Outcomes In Pediatric Cardiac Icu Patients, Marissa A Brunetti, Heather M Griffis, Michael L O'Byrne, Andrew C Glatz, Jing Huang, Kurt R Schumacher, David K Bailly, Yuliya Domnina, Javier J Lasa, Michael Alice Moga, Hayden Zaccagni, Janet M Simsic, J William Gaynor

Faculty, Staff and Students Publications

Background: Previous studies have reported racial disparities in extracorporeal membrane oxygenation (ECMO) utilization in pediatric cardiac patients.

Objectives: The objective of this study was to determine if there was racial/ethnic variation in ECMO utilization and, if so, whether mortality was mediated by differences in ECMO utilization.

Methods: This is a multicenter, retrospective cohort study of the Pediatric Cardiac Critical Care Consortium clinical registry. Analyses were stratified by hospitalization type (medical vs surgical). Logistic regression models were adjusted for confounders and evaluated the association between race/ethnicity with ECMO utilization and mortality. Secondary analyses explored interactions between race/ethnicity, insurance, and socioeconomic status …

Prevalence Of Depression, Anxiety And Stress After The Covid-19 Pandemic Period Among Students At The Medical University Of Sofia; Significance Of Demographic, Educational, And Pandemic-Related Variables, Nadya Avramova

Journal of Mind and Medical Sciences

This cross-sectional study aimed to determine the prevalence of depression, anxiety, and stress among undergraduate dental students at Sofia Medical University and to investigate its associations with some demographic, educational and pandemic-related variables. A self-reported questionnaire that included the validated DASS-21 scale was administered to a group of 2nd, 3rd, 4th, and 5th year students (n=70, response rate 95.7%). Results indicated abnormal levels of depression, anxiety, and stress in 34.3%, 65.7% and 59.7% of the participants, respectively. A much larger proportion of females suffered from abnormal levels of anxiety (56.6%) as compared with males (9%), p=.003. Single students exhibited significantly …

The Addition Of Nature To The Patient's Healing Regimen, Katelyn Lewis, Audrey Henry

Scholars Week

Through our scholarly research, we have found many benefits to the use of nature to help facilitate healing within patients. Our project aims to spread awareness of the positive aspects of nature during the healing process. Specifically, our research focuses on healing gardens and outside therapy for patients. Our presentation is based upon Nightingales' theory of the environment. Our hope is that facilities will implement the addition of nature to the patient's plan of care.

Effects And Treatments Of Depression Affecting Patient Outcomes, Parker Gerard

Scholars Week

No abstract provided.

Momentary Shame & Executive Function: Negative Self-Attribution As A Precursor To Performance Error, Mary M. Bryan

Master's Theses & Other Graduate Student Works

Individuals who experience momentary shame experiences may attribute a sense of wrongdoing to their identity. Witnessing one's violation of social mores may promote withdrawal, rumination, and/or aggression, which may restrict cognitive processes that affect typical executive function. In particular, task initiation, inhibition, and cognitive flexibility were selected when measuring levels of executive dysfunction. 10 participants were asked to complete shame and executive function pre-screeners, a shame- or neutral-affective writing task, and a real-time executive function measure. Results suggest that those who self-reported higher levels of shame proneness and underwent a shame-affective stimulus may have displayed improved inhibition and cognitive flexibility. …

The Posttraumatic Stress Disorder Of Frodo Baggins, Bruce D. Leonard

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

J.R.R. Tolkien in The Lord of the Rings accurately portrayed the signs and symptoms of what is currently labeled Post Traumatic Stress Disorder. Frodo’s condition logically follows his experiences of less than a year in the War of the Ring. Tolkien did not have access to a diagnostic manual but apparently used his keen observations from both World Wars to inform his narrative. No fantasy is employed to describe Frodo condition after the Ring is destroyed. His condition is that of a vet with PTSD. Evidence from the History of Middle-earth demonstrates the deliberate steps taken to show Frodo as …

Ataque De Nervios: A Culturally-Bound Syndrome Unique From Panic Disorder, Faiza Ahmad, Alcides Amador

MEDI 9331 Scholarly Activities Clinical Years

We present the case of Ms. MR, a 71 year old female who arrived at the outpatient clinic for evaluation of a long-standing history of depressive symptoms and dissociative emotional spells. She describes a history of sudden-onset “emotional episodes” in which she experiences uncontrollable sobbing, loses control of her arms and legs, and becomes unresponsive for 5-7 minutes. We believe this patient may be experiencing ataques de nervios (“attack of nerves”), a culturally-bound syndrome most commonly affecting Hispanic populations.

Fibrinogen; A Predictor Of Injury Severity And Mortality Among Patients With Traumatic Brain Injury In Sub-Saharan Africa: A Cross-Sectional Observational Study, Michael Devereaux, Martha Sajatovic

Faculty Scholarship

Studies show that fibrinogen concentrations <2 g/L in patients with traumatic brain injury (TBI) is associated with increased mortality. However, little is known regarding fibrinogen levels and TBI severity as well as mortality in sub-Saharan Africa despite shouldering a high burden of TBI. We therefore set out to determine whether fibrinogen levels are associated with TBI severity and outcome. To determine the sensitivity and specificity of fibrinogen levels and the association with severity and mortality among TBI patients at Mulago Hospital. We prospectively enrolled 213 patients with TBI aged between 13 and 60 years of age and presenting within 24 hours of injury. Patients with preexisting coagulopathy, concurrent use of anticoagulant or antiplatelet agents, preexisting hepatic insufficiency, diabetes mellitus and who were pregnant were excluded. Fibrinogen levels were determined using the Clauss fibrinogen assay. Logistic regression analyses were conducted to identify the association between fibrinogen level and 7-day outcomes. Majority of the patients were male (88.7%) and nearly half were aged 30 or less (48.8%). Fibrinogen levels <2 g/L were observed in 35.1% of the study participants. The average time spent in the study was 3.7 ± 2.4 days. The sensitivity and specificity using fibrinogen <2 g/L was 56.5% and 72.9% respectively. Fibrinogen levels predict TBI severity with an AUC = 0.656 (95% CI 0.58-0.73: P = .000) Fibrinogen levels <2 g/L (hypofibrinogenemia) were independently associated with severe TBI. (Adjusted odds ratio 2.87 CI, 1.34-6.14: P = .007). Levels above 4.5 g/L were also independently associated with injury severity (adjusted odds ratio 2.89, CI 1.12-7.48: P < .05) Fibrinogen levels more than 4.5 g/L were independently associated with mortality (OR 4.5, CI; 1.47-13.61, P < .05). The fibrinogen level is a useful tool in predicting severity including mortality of TBI. Fibrinogen levels may be used as an additional tool to screen TBI patients for injury severity especially among patients with Glasgow coma scale scores of <14.

Blood Pressure Variability And Early Neurological Outcomes In Acute And Subacute Stroke In Southwestern Uganda, Shirley M. Moore, Martha Sajatovic

Faculty Scholarship

Background: Greater blood pressure variability has detrimental effects on clinical outcome after a stroke; its effects are controversial and have not been evaluated in Sub-Saharan Africa (SSA). Methods: We conducted a prospective study of patients with CT head confirmed ischemic and hemorrhagic strokes admitted to a tertiary hospital within 7 days of onset of unilateral neurological deficits. Blood pressure variability indices, standard deviation (SD) and coefficient of variation (CV) of systolic and diastolic blood pressure between day 0 and day 7, were calculated with a subsequent modified Rankin Scale (mRS) score on day 14 post-stroke. Linear regression was performed to …

Assessing The Mental Health Of Older Hispanic/Latinx Adults: Focus On The Impact Of The Hispanic Cultural Value Of Fatalismo On Depressive Symptomatology, Anna J. Prado, Amie Bostic, Mario Gil

Research Colloquium

Introduction: The impact of depression in older Hispanic/Latinx adults in the United States is poorly understood. The influence of the deeply embedded Hispanic/Latinx cultural value of fatalismo, referring to the belief that one’s future is predetermined and related to feelings of helplessness, has been found to negatively impact their psychological health [1, 2]. The present study explores the association between the Hispanic/Latinx cultural value of fatalismo and mental health.

Objective: To contribute to the identification and understanding of psycho-social-cultural determinants of depression in the Hispanic/Latinx population.

Methods: Using data from the Health and Retirement Study (HRS) …

A Preliminary Timeline Of The Midbrain Development In The Monodelphis Domestica Animal Model, Ismael Perez, John L. Vandeberg, Mario Gil

Research Colloquium

Introduction: The Brazilian short-tailed opossum (Monodelphis Domestica) is an understudied animal model compared to the Mus musculus that has been identified as a perfect candidate to study neurodevelopment (Baggott, L. & Moore, H., 1990). What makes the Monodelphis Domestica a perfect specimen for neurodevelopment is that the embryo develops outside the pouch of the mother providing easy noninvasive access to track changes across different developmental stages (Mate et al., 1994).

Objective: The objective of the study is to compare the area and volume in the development of the Monodelphis’s midbrain across three different developmental stages. Our research is beneficial because …

The Design And Impact Of A Clinic-Based Community Program On Food Insecurity, Healthy Eating Behaviors, And Mood, Tiffany Wesley Ardoin, Elizabeth Perry, Chelsea Morgan, Jared Hymowitz, Donald Mercante

School of Medicine Faculty Publications

Food insecurity is a national issue that disproportionately impacts Louisiana citizens, contributing to the state’s poor health outcomes. We know that the Supplemental Nutrition Assistance Program (SNAP) and food pantries improve access to food, but we have limited data on what interventions improve food insecurity. The Geaux Get Healthy Clinical Program at Our Lady of the Lake (GGHOLOL) is a clinic-based community program that leverages community partnerships and a clinical setting to provide education and access to resources for individuals with food insecurity. This prospective study examines the impact of GGHOLOL on food insecurity as a pre-post survey evaluation over …

Specialized Late Cingulo-Opercular Network Activation Elucidates The Mechanisms Underlying Decisions About Ambiguity, Jordan E. Pierce, Nathan M. Petro, Elizabeth Clancy, Caterina Gratton, Steven E. Petersen, Maital Neta

Center for Brain, Biology, and Behavior: Faculty Publications

Cortical task control networks, including the cingulo-opercular (CO) network play a key role in decision-making across a variety of functional domains. In particular, the CO network functions in a performance reporting capacity that supports successful task performance, especially in response to errors and ambiguity. In two studies testing the contribution of the CO network to ambiguity processing, we presented a valence bias task in which masked clearly and ambiguously valenced emotional expressions were slowly revealed over several seconds. This slow reveal task design provides a window into the decision-making mechanisms as they unfold over the course of a trial. In …

Covid-19 And Friendships: Agreeableness And Neuroticism Are Associated With More Concern About Covid-19 And Friends' Risky Behaviors, Jessica D. Ayers, Diego Guevara Beltrán, Andrew Van Horn, Lee Cronk, Hector Hurmuz-Sklias, Peter M. Todd, Athena Aktipis

Psychological Sciences Faculty Publications and Presentations

Given the importance of friendships during challenging times and the mixed associations between personality traits and disease-related behaviors, we investigated the correlations between personality traits and perceptions of friendships during the COVID-19 pandemic. Data were collected as part of a longitudinal investigation of the correlations between the pandemic and various cooperative relationships. In this investigation, we found that agreeableness and neuroticism predicted participants being more concerned about COVID-19 and bothered by friends' risky behavior, and extraversion predicted enjoying helping friends during the pandemic. Our results suggest that personality differences are associated with how individuals cope with friends' risky behaviors during …

An Occupational Therapy Assessment Guide For People With Posttraumatic Stress Disorder, Cynthia Sakian, Steven M. Gerardi

Fall 2023 Virtual OTD Capstone Symposium

This poster presents development of an occupational therapy assessment guide tailored for individuals with posttraumatic stress disorder. Motivated by the lack of standardized assessment protocols in the field, the initiative seeks to mitigate inconsistencies among occupational therapy practitioners and propel advancements in treatment. Key objectives include a comprehensive review of pertinent literature on occupational therapy and posttraumatic stress disorder, identification of functional impairments associated with the disorder, and the formulation of an assessment framework. Rooted in the Model of Human Occupation, the guide underscores the significance of volition, habituation, performance capacity, and environmental influences, accommodating individual preferences and disruptions while …

Context At The Periphery: The Rise Of The Critical-Contextual Legal Education Reform Movement, Cara R. Shaffer

Cardozo Journal of Equal Rights & Social Justice

The article argues that legal education must reform by integrating critical-contextual approaches to address declining critical thinking skills and better prepare students for contemporary legal practice. It emphasizes the need to move beyond the traditional Langdell case method, which separates doctrinal learning from practical and contextual understanding, and highlights the importance of interdisciplinary perspectives in legal training.