Psychiatry and Psychology Commons^™

Exploring Differences In Cannabis Use And Harm Perceptions Among Sexual Minority And Heterosexual Females: A Brief Report, Sarah J. Ehlke, Samantha A. Fitzer, Kendra Rigney

Psychology Faculty Publications

Objective: Sexual minority women (SMW) have higher rates of cannabis use compared to heterosexual women, which may be partially attributed to lower harm perceptions. However, no study has examined if the association between harm perceptions and cannabis use is stronger for SMW than heterosexual women. This study examined if sexual identity (SMW vs. heterosexual woman) moderated the association between harm perceptions and past 30-day cannabis use among a sample of female young adults (18-25 years old). Method: Participants were 949 (29.8% SMW; Mean age = 24.33; 92.1% non-Hispanic White) females (99.3% cisgender) recruited from Amazon Mechanical Turk who reported weekly …

Using Mindfulness To Manage Moral Injury In Veterans: Feasibility And Satisfaction Of A Pilot Randomized Controlled Trial, Michelle L. Kelley, Adrian J. Bravo, Elizabeth E. Burgin, Susan A. Gaylord, Christine Vinci, Megan Strowger, Jeffrey M. Gabelmann, Joseph M. Currier

Psychology Faculty Publications

Objective

The present study assessed program feasibility and satisfaction among recent-era veterans who participated in Mindfulness to Manage Moral Injury (MMMI), a live facilitated web-based 7-week mindfulness-based program targeting moral injury among veterans.

Method

In total, 56 post-9/11 veterans were recruited with 28 randomized to the MMMI condition and 28 to the Education and Support (ES) condition. Most participants identified as being White (71.4%), male (66.1%), and had a reported mean age of 41.50 years (Median = 39.50, SD = 9.26).

Results

Among the 56 participants, 82.1% attended at least one treatment session and 44.6% completed all seven sessions. There …

Pregnant Adults' Interest In Physical And Mental Health Behavior Change Interventions Using Mobile Technology, Natalie M. Yarish, Cassidy M. Sandoval, Alicia Moulder, Meredith I. Turner, Danielle Symons Downs, Kristin E. Heron

Psychology Faculty Publications

Improving the health and well-being of pregnant adults is an important public health priority in the USA, and mobile health (mHealth) interventions may provide a scalable strategy to disseminate behavior change programs to pregnant adults. This study assessed pregnant people’s use of mobile technology, interest in making health behavior changes during and after pregnancy, and their willingness to use mHealth interventions. Participants were 133 pregnant adults (M_age = 27.86; 81% White) living across the USA recruited from social media to complete an online survey. Measures assessed mobile technology use and beliefs about improving mental/physical health in pregnancy and postpartum …

Evaluation Of A 20-Item Version Of The Trauma-Related Drinking To Cope Questionnaire, Sage E. Hawn, Lauren Smith, Kaytlin Armitage, Selah Ball, Cathy Lau-Barraco, Abigail Powers, Ananda B. Amstadter

Psychology Faculty Publications

Objectives: This study sought to develop and psychometrically evaluate an expanded version of the Trauma-Related Drinking to Cope (TRD) scale, a four-item self-report tool, which was developed to address a crucial gap in self-medication research. Before the development of the TRD, no measures existed which assessed alcohol use for coping with symptoms of posttraumatic stress disorder (PTSD) specifically. Previous work showed that the TRD has strong psychometric properties and clinical utility in its ability to identify individuals with PTSD who may be at risk for developing comorbid alcohol use disorder (AUD). The aim of the present study was to develop …

Vagally Mediated Heart Rate Variability Modulates The Association Between The Perceived Workload And The Stroop Effect On Behavioral Performance, Xiao Yang, Michael Gazzanigo, Fang Fang, Spencer House

Psychology Faculty Publications

Vagally mediated heart rate variability (vmHRV) reflects top-down cognitive processes involved in emotion-cognition integration. Using cognitive control can be effortful and increase negative affect. However, this intrinsic affective component of cognitive control has not been well studied, and the role of vmHRV in the association between subjective experience in using cognitive control and behavioral performance remains unknown. The current study aimed to examine the relationship of vmHRV with cognitive control and perceived workload in a cognitive task. Eighty-one participants performed the Stroop interference task. Participants rated subjective workload using the NASA Task Load Index (NASA-TLX) scale for congruent and incongruent …

The Perceived Internalized Sexual Stigma Measure (Prissm): A New Sexual Stigma Measure For Lesbian, Gay, And Bisexual Individuals, Miguel A. Padilla, Lacey M. Schlappi, Evelyn S. Chiang

Psychology Faculty Publications

Society has long held negative beliefs and attitudes, in the form of sexual stigma, towards sexual minorities (e.g., lesbian, gay, and bisexual; LGB). Sexual stigma can be adopted and internalized by LGB individuals as their own beliefs and attitudes. In LGB individuals, internalized sexual stigma can result in psychological distress such as low self-esteem, depression, shame, and feelings of rejection. However, an instrument to assess internalized sexual stigma specifically developed for LGB individuals is lacking. The present study focuses on the development of a new instrument, the Perceived Internalized Sexual Stigma Measure (PrISSM), that is inclusive of LGB individuals who …

A Multilevel Framework For The Promotion Of Maternal Mental Health And Well-Being During The Perinatal Period, Jenn A. Leiferman, Jessica Walls Wilson, Charlotte V. Farewell, Chelsea Walker-Mao, James F. Paulson

Psychology Faculty Publications

Background: Depression and anxiety are prevalent in the perinatal period and may contribute to adverse maternal and child health outcomes. A focus on multilevel protective factors may be effective in promoting well-being and increasing quality of life (QOL) in the perinatal period while simultaneously reducing or preventing depression and anxiety symptoms. We tested a conceptual model that posits specific personal, social, and community factors affecting depression, anxiety, and QOL among pregnant and postpartum individuals.

Methods: Four hundred and thirty-eight pregnant or postpartum individuals completed a 121-item cross-sectional survey composed of validated tools that assessed multilevel protective factors, health behaviors, and …

How Marriage And Family Therapy Graduate Programs Awaken, Develop, And Teach Clinical Intuition: A Hermeneutic Qualitative Phenomenological Study, Jessica Fountas

Antioch University Dissertations & Theses

This research explored how marriage and family therapy graduate programs awaken, develop, and teach clinical intuition. Using criterion-based sampling and snowball sampling, six licensed marriage and family therapists participated in a two-step hermeneutic phenomenological study consisting of individual semistructured interviews and a follow-up focus group. Requirements for participation were licensed marriage and family therapists who were in clinical practice, had experienced the phenomenon of clinical intuition and awakening of clinical intuition, and used clinical intuition in therapy with clients and in systemic supervision with supervisees. The research findings highlighted 14 themes: Reflection of the Experience of Clinical Intuition; Bodily Knowing, …

Childhood Aggression: A New Conceptualization, Hannah G. Harrison

Antioch University Dissertations & Theses

Childhood aggression is a frequently observed behavioral phenomenon, yet lacks a precise
definition in both the DSM-5-TR and current research literature. Definitional ambiguity and
construct enmeshment continue to create construct confusion for researchers, clinicians, and
informants. This empirical review of the current literature and diagnostic criteria examines how
childhood aggression has been historically conceptualized, defined, and described. The primary
aim was to identify and clarify inconsistencies in current definitions and to address knowledge
gaps to improve diagnostic clarity. Through a thematic synthesis of recent literature, several key
issues emerged: the absence of a precise definition of childhood aggression; reliance on …

Investigating Protective And Risk Factors And Predictive Insights For Aboriginal Perinatal Mental Health: Explainable Artificial Intelligence Approach, Guanjin Wang, Hachem Bennamoun, Wai Hang Kwok, Jenny Paola Ortega Quimbayo, Bridgette Kelly, Trish Ratajczak, Rhonda Marriott, Roz Walker, Jayne Kotz

Research outputs 2022 to 2026

Background: Perinatal depression and anxiety significantly impact maternal and infant health, potentially leading to severe outcomes like preterm birth and suicide. Aboriginal women, despite their resilience, face elevated risks due to the long-term effects of colonization and cultural disruption. The Baby Coming You Ready (BCYR) model of care, centered on a digitized, holistic, strengths-based assessment, was co-designed to address these challenges. The successful BCYR pilot demonstrated its ability to replace traditional risk-based screens. However, some health professionals still overrely on psychological risk scores, often overlooking the contextual circumstances of Aboriginal mothers, their cultural strengths, and mitigating protective factors. This highlights …

Psychotropic Polypharmacy In Dementia: A Retrospective Analysis For People With Neuropsychiatric Symptoms Referred To An Australian Dementia Support Service, Mustafa Atee, Andrew Stafford, Daniel Whiting, Ya Ping Lee, Christopher Morrow, Guillaume Nyakaboyi, Ella Warnes, Thomas Morris

Research outputs 2022 to 2026

Background and Objectives: Despite their limited benefits and serious adverse effects, psychotropics remain frequently prescribed for neuropsychiatric symptoms (NPS) of dementia. Psychotropic polypharmacy, the use of two or more concomitant psychotropic medications, is therefore not recommended for people with dementia. The objectives of this study were to investigate the prevalence of psychotropic polypharmacy in Australians living with dementia whose caregivers sought external NPS support from Dementia Support Australia (DSA; the national provider of NPS support) and the association of psychotropic polypharmacy with their demographics and NPS characteristics. Methods: A retrospective cross-sectional study of a subset of DSA referrals at baseline …

Alexithymia And Impulsivity In Combat Sports – A Tale Of Three Measures, Craig A. Harms, Oliver R. Barley

Research outputs 2022 to 2026

The purpose of this study was to compare the psychometric properties of two measures of alexithymia – the Toronto Alexithymia Scale (TAS-20) and the Perth Alexithymia Questionnaire (PAQ) – as well as the Barratt Impulsiveness Scale 11 measure of behavioural impulsivity because the psychometric properties of these scales have not been established in athletes. As part of a larger study, 298 participants completed an online survey that included the TAS-20, PAQ, and BIS 11, as well personal- (age and gender) and sport-specific (primary combat sport and level of competition) demographic measures. A unidimensional model was retained for the TAS-20. A …

Effects Of High-Frequency Repetitive Transcranial Magnetic Stimulation On Impulse Control Disorders In Patients With Parkinson’S Disease On Dopamine Replacement Therapy, Katherine Muksuris

Graduate Theses, Dissertations, and Problem Reports (ETD)

Parkinson’s Disease (PD) is a debilitating neurodegenerative disorder that causes motor deficits, cognitive impairment, and depression. The mainstay treatment for motor symptoms is dopamine replacement therapy (DRT). DRT takes the form of levodopa or dopamine receptor agonists (DAs) and can be associated with impulse control disorders (ICDs). Currently, the approach to mitigating these side effects is to decrease or stop DRT, which may cause motor symptoms to return, making the management of the disorder more difficult. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation treatment for multiple disorders, including its approved use for smoking cessation. It has also shown …

Exploration Of Coping And Mental Health In West Virginia Farmers, Jodi Meadows Richmond

Graduate Theses, Dissertations, and Problem Reports (ETD)

Compared nationally, West Virginia currently ranks lowest for life expectancy, highest for drug related deaths and 35^th for access to adequate health (WV DHHR Organization Assessment & Strategic Plan, 2022). The state also ranks first in the nation for depression with one in four adults experiencing some form of depressive condition each year (CDC, 2020). The rurality of the state may limit social interaction and availability of medical treatment facilities (Brew et al., 2016).

The situation is even more dire for those in farming-related occupations. Farmers often struggle with management stress, utilizing appropriate coping strategies, and accessing mental health …

The Gut-Brain Axis: Investigating The Effects Of Diet, Physical Activity, And Prior Adversity On Anxiety Via Autonomic Nervous System, Jenna L. Pennella

UNF Graduate Theses and Dissertations

Previous literature has highlighted a bidirectional relationship between the gut and brain called the gut-brain axis (de Punder & Pruimboom, 2015; Hill et al., 2008; Leistner & Menke, 2020). The current study aimed to investigate directional relations between different stressors (e.g. poor diet, vigorous activity, and prior adversity) and anxiety and how interactions with gut issues and autonomic dysfunction may impact these relationships. Based on previous literature, we examined (a) physical activity and diet as moderators of stress and anxiety as well as stress and GI symptoms, (b) GI symptoms as a mediator between various predictors (i.e., diet, stress, physical …

Evaluation Of The Stigmatizing Attitude Towards Mental Illness Among A Group Of Egyptian Nonpsychiatric Physicians, Mohamed Elhasanein Elshehedy, Mahmoud Ahmed Elwasify, Ibtihal Mohamed Aly Ibrahim, Roshdy Mohamed El Gamal

Mansoura Medical Journal

Background Stigmatizing attitudes toward persons had mental illness remain a major barrier to effective mental healthcare. While psychiatrists’ perspectives have been studied extensively, less attention has been paid to non-psychiatric physicians, whose attitudes significantly influence early detection and referral. Objective To evaluate stigmatizing attitudes toward mental illness among Egyptian nonpsychiatric physicians. Methods This cross-sectional research has been performed on a sample of non-psychiatric physicians in various Egyptian events and occasions, including the Mansoura University conference, the Ain Shams University conference, and the Alexandria University conference over the year 2023. Participants completed a socio-demographic questionnaire and the Mental Illness Clinicians’ Attitudes …

The Emotional Landscape Of Aviation Pilots: Analysis Of Online Professional Forums Using Natural Language Processing, Adrienne S. Renwick, Leo Gonzalez, Charles L. Silber, Alyson Mullen, Cass Dykeman, Adam Stewart, Jennifer C. Ross, James Geisler

Journal of Aviation/Aerospace Education & Research

This study investigated burnout related to emotions in three categories of pilots: commercial passenger, commercial cargo, and military. While pilot burnout has been previously studied, challenges in self-reporting limit understanding. This study extends previous research by analyzing pilots' anonymous online forum posts to gain insight into burnout-related emotions. Natural Language Processing was conducted with the RoBERTa-base-go_emotions model, which analyzed 1,130,530 online forum posts from commercial passengers, commercial cargo, and military pilots for 27 emotion categories and one absence of emotion category (i.e., neutral). An exploratory composite score reflecting burnout-related emotional expression omnibus burnout score was calculated using seven burnout-related emotions …

Reduced Set-Shifting Processing Speed In Male Rats Following Low Dose (10 Cgy) Proton Exposure, Hui Ho Vanessa Chang, Gyutae Kim, Kyu-Sung Kim, Richard A. Britten

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

Space radiation (SR) exposure poses significant biomedical risks, including effects on the central nervous system (CNS). These risks are particularly relevant to cognitive function during long-duration space missions. One critical cognitive skill is decision-making, which requires attentional set-shifting (ATSET)—the ability to quickly assess problems, evaluate options, and select the best actions. Previous studies have shown that exposure to However, the impact of low LET (< 1 keV/μm) protons, which significantly contribute to the total radiation flux astronauts encounter within spacecraft, on ATSET performance is unknown. To address this gap, we evaluated the effects of cranial irradiation with 10 cGy of 100 MeV/n protons (LET = 0.732 keV/μm) on ATSET performance in male Sprague-Dawley rats. We also investigated whether concurrent exposure to variable gravity (hypergravity step-up, step down, purported to have the same effect as exposure to microgravity (another major spaceflight stressor) exacerbated SR-induced cognitive deficits. Our findings indicate that proton exposure alone significantly impaired ATSET performance, as evidenced by decreased processing speed while performing compound discrimination reversal and extra-dimensional shifting. Notably, no additive or synergistic effects were observed when hypergravity was combined with proton exposure. The impact that low-dose proton exposure has on CNS functionality, particularly in reducing processing speed during complex tasks, warrant further investigation. If similar cognitive deficits were to occur in astronauts exposed to galactic cosmic rays, mission success and safety could be significantly compromised.

A Critical Examination Of Scent Avoidance And Olfactory Development After Neonatal Predator Scent Exposure, Cynthia Ware

College of Graduate Studies: Theses & Dissertations

The long-standing assumption that predator odor avoidance in rodents is an innate survival mechanism has shaped decades of behavioral neuroscience research and underpins translational models of post-traumatic stress disorder (PTSD). However, developmental systems theory (DST) posits that behaviors emerge from dynamic interactions across physiological and environmental systems over time, rather than from fixed genetic programs. This study critically evaluates the developmental plasticity of predator scent aversion by examining whether early-life exposure to red fox urine (a natural predator odor) can attenuate avoidance behaviors in Long–Evans rats. Seventy-one rats were bred into three conditions: Control (no exposure), Partial (exposure from birth), …

Mobile Health Intervention Tools Promoting Hiv Pre-Exposure Prophylaxis Among Adolescent Girls And Young Women In Sub-Saharan Africa: Scoping Review, Alex Emilio Fischer, Homaira Hanif, Jacob B. Stocks, Aimee E. Rochelle, Karen Dominguez, Eliana Gabriela Armora Langoni, H. Luz Mcnaughton Reyes, Gustavo F. Doncel, Kathryn E. Muessig

Department of Obstetrics & Gynecology Faculty Publications

Background:

In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited uptake and persistence. Mobile health (mHealth) interventions can improve medication adherence; however, their utility to improve PrEP adherence among adolescent girls and young women is not well established.

Objective:

This scoping review synthesizes evidence supporting mHealth for PrEP among adolescent girls and young women in sub-Saharan Africa and identifies strategies for further evaluation.

Methods:

We searched PubMed and Google Scholar databases, expert referrals, and reference lists using the following eligibility …

The Dynamics Of Mystical Experiences: Interaction Effects And Distinct Contributions Of Meq-30 Factors, Genevieve Falabella

Electronic Theses & Dissertations (2024 - present)

Many participants in clinical trials of psychedelic-assisted therapy (PAT) report mystical experiences. Researchers often use the 30-item Mystical Experience Questionnaire (MEQ-30) to measure mystical experiences. Several studies have validated a four-factor structure of the MEQ-30, but only as a subset of items within broader versions of the scale (e.g., MEQ-43). As such, the factor structure of the standalone MEQ-30 remains unvalidated in English. Additionally, some data suggest that certain factors might be more strongly associated with psychedelic-associated outcomes than others, which could provide insight to enhance the therapeutic potential of PAT. The aim of this study was to examine the …

Psychedelic Minimalism: The Case Against Music In Psychedelic Therapy Settings, Samir A. Nader

Department of Medicine Faculty Publications

[Introduction: reframing the role of setting] In recent years, renewed attention has been given to the centrality of set and setting in psychedelic-assisted therapy. The Reporting of Setting in Psychedelic Clinical Trials (ReSPCT) guidelines reflect an evolving consensus: therapeutic outcomes are not solely pharmacologically determined but are heavily shaped by both the environment and the psychological state of the participant (2). Within this evolving paradigm, music has assumed a privileged role, framed as a therapeutic constant, typically curated to be emotionally supportive or evocative, and especially emphasized during peak psychedelic states (3). The prevailing assumption is that music facilitates safety, …

Can The Ability To Infer Relevance Account For Dimensional Psychoticism? An Exploration Of A Representative Community Sample, Adam Schwarz, Frank D. Baughman, Evan Dauer, Ruby Koyllor Alarcon Gleeson, Jennifer Haywood, Bo Huei Huang, Karen H. Heslop, Barbara A. Mullan, Susan L. Rossell, Nicolas H. Hart, Darren Haywood

Research outputs 2022 to 2026

Purpose: Psychoticism is a common feature of psychological disorders. Deficits in perceptual inference have been associated with the development of psychotic symptoms. Traditional testing of perceptual inference has had low ecological validity, limiting the ability to infer functional relationships. The aims of this study were to investigate the relationship between the capacity to infer relevance in dynamic environments and dimensional psychoticism, as well as to investigate the association between inferring relevance and dimensional psychoticism. Method: Four hundred participants, representative of the general population of the USA, completed an online questionnaire consisting of the Brief Symptom Inventory, as well as demographic …

Drinking Motives And Alcohol Sensitivity Mediate Multidimensional Genetic Influences On Alcohol Use Behaviors, Jeanne E. Savage, Spit For Science Working Group, Danielle M. Dick

Psychology Faculty Publications

Background

Genetic influences account for a substantial proportion of individual differences in alcohol use behaviors (AUBs). However, multiple distinct sets of genes are linked to different AUBs via uncertain causal links. Here, we explore whether intermediate neurobiological traits mediate the relationship between polygenic scores (PGSs) and multiple AUBs, with the aim to better understand processes captured by different genetic profiles.

Methods

We derived four alcohol-related PGSs in participants from Spit for Science, a longitudinal study of college students in the United States (n=4549). Using linear regression, we tested the relationship between PGSs and 22 potential mediators, including personality, …

Integrated Multi-Omics Analyses Of Synaptosomes Revealed Synapse-Associated Novel Targets In Alzheimer’S Disease, Subodh Kumar, Enrique Ramos, Axel Hidalgo, Daniela Rodarte, Bhupender Sharma, Melissa M. Torres, Davin Devara, Shrikanth Gadad

School of Medicine Publications

Synapse dysfunction is an early event in Alzheimer’s disease (AD) caused by various factors, including amyloid beta, p-tau, inflammation, and aging. However, the precise molecular mechanism underlying synapse dysfunction in AD remains largely unknown. To understand this, we comprehensively analyzed the synaptosomes fraction in post-mortem brain samples from AD patients and cognitively normal individuals. We conducted high-throughput transcriptomic analyses to identify changes in microRNA (miRNA) and mRNA levels in synaptosomes extracted from the brains of unaffected individuals and those with AD. Additionally, we performed mass spectrometry analysis of synaptosomal proteins in the same sample group. These analyses revealed significant differences …

The Multifaceted Interplay Between Covid-19-Induced Psychological Stress, Cognitive Flexibility, Emotional Overeating, And Physical Activity Patterns In Adult Women: A Mediated Path Analysis, Siavash Naddafha, Mandana Sangari, Zohreh Eskandari, Robabeh Shahnahadd, Christopher B. Taber

Research outputs 2022 to 2026

Objective: To determine how COVID-19-related stress influences food consumption and emotional overeating in adult women, and whether cognitive flexibility and physical activity mediate these relationships. Methods: In this cross-sectional study, 303 women (20–50 y) completed validated Persian versions of the COVID Stress Scale-18, Adult Eating Behaviour Questionnaire, Self-Regulation of Eating Behaviour Questionnaire, Cognitive Flexibility Scale, and Rapid Assessment of Physical Activity. Data were collected online via the ISO-27001-certified “Press Line” platform (end-to-end encryption). Chi-square tests and Spearman’s rank correlations were performed in SPSS 19 (α = 0.05). Results: COVID-19 stress was strongly inversely associated with cognitive flexibility (rₛ = – …

The Physiological Consequences Of And Recovery Following The Australian Special Forces Selection Course, Angela C. Uphill, Kristina L. Kendall, Bradley A. Baker, Stuart N. Guppy, Hannah M. Brown, Michael Vacher, Bradley C. Nindl, G. Gregory Haff

Research outputs 2022 to 2026

This study aimed to determine the energy requirements, physiological consequences, and recovery rate from the Australian Special Forces Selection Course. Ninety-three male soldiers (mean ± SD, 28.1 ± 3.6 years, 1.81 ± 0.1 m, 85.1 ± 8.1 kg) vol-unteered for this study. Body composition via dual-energy X-ray absorptiometry, hormones and resting metabolic rate were assessed before, immediately after, and at 1, 3, 5, and 8 weeks post-course. Energy expenditure, assessed via doubly-labelled water during the first 10 days of the course significantly exceeded energy intake (expenditure: 7680 ± 1095 kcal. day–1, in-take: 3859 ± 704 kcal. day– 1). Body mass …

Psychological Impacts In Exercise Riders And Professional Jockeys Following Injury, Kelley M. Renner

Theses and Dissertations--Kinesiology and Health Promotion

One of the most well-known equestrian sports, horse racing, is not only a cornerstone of Kentucky’s economy, but also a vital part of its culture, with professional jockeys playing an essential role in the local communities and traditions that define the state. Despite its popularity and financial impact, mental health challenges within the sport have continually been shrouded in silence and ignored in research (Ball et al., 2007). Equally concerning is the high injury prevalence, and psychological impact of these injuries (e.g., psychological distress, depression, anxiety, loss of identity, and self-esteem (King et al., 2022; Losty et al., 2019; McConn-Palfreyman …

The Pointer Imaging Baseline Cohort: Associations Between Multimodal Neuroimaging Biomarkers, Cardiovascular Health, And Cognition, Theresa M Harrison, Tyler Ward, Jacinda Taggett, Pauline Maillard, Samuel N Lockhart, Youngkyoo Jung, Laura C Lovato, Robert Koeppe, William J Jagust, Danielle Harvey, Joseph C Masdeu, Hwamee Oh, Darren R Gitelman, Neelum T Aggarwal, Mark A Espeland, Maryjo L Cleveland, Rachel Whitmer, Sarah Tomaszewski Farias, Stephen Salloway, Valory Pavlik, Melissa Yu, Christine Tangney, Heather Snyder, Maria Carrillo, Laura D Baker, Prashanthi Vemuri, Charles Decarli, Susan M Landau

Staff and Researcher Publications

Introduction: The U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER) is evaluating lifestyle interventions in older adults at risk for cognitive decline and dementia. Here we characterize the baseline data set of the POINTER Imaging ancillary study.

Methods: Participants underwent health and cognitive assessments and neuroimaging with multimodal positron emission tomography (PET) (beta-amyloid [Aβ] and tau) and magnetic resonance imaging (MRI). Framingham risk score (FRS) was used to quantify cardiovascular disease (CVD) risk.

Results: A total of 1052 participants (31% from underrepresented ethnoracial groups) were enrolled. Compared to Aβ-, Aβ+ (29%) participants were older, …

Aerodigestive Sequelae And Triple Endoscopy After Congenital Tracheoesophageal Fistula Repair In Children, Whitney Jin, Eric H Chiou, Shailendra Das, Kathleen E Hosek, Elton M Lambert

Faculty, Staff and Students Publications

Children post-tracheoesophageal fistula (TEF) repair may present with chronic respiratory and gastrointestinal symptoms that can affect quality of life.

OBJECTIVE: To identify factors associated with positive findings on triple endoscopy following neonatal TEF repair.

STUDY DESIGN: Case series with retrospective review of patients.

SETTING: Tertiary care center aerodigestive program.

METHODS: Children with neonatally repaired congenital TEF who had a triple endoscopy between 2011 and 2022 were reviewed. The presence of chronic cough, recurrent pulmonary infections, lipid-laden macrophages (LLM), and airway and esophageal anomalies were among the variables analyzed. Chi-square and Kruskal-Wallis univariate analysis was performed.

RESULTS: The mean age was …