Nutritional and Metabolic Diseases Commons^™

Exploring Geriatric Self Management Of Type 2 Dm: A Systematic Review, Ahmed Gawash, David F. Lo, Kunal P. Shah, Jasmine Emanuel, Brandon Goodwin, Don D. Shamilov, Gaurav Kumar, Nathan Jean, Christian P. White

Rowan-Virtua Research Day

This review explores diabetic self-management in geriatric individuals, focusing on positive attitudes and support from family/friends as crucial for self-care optimization. A comprehensive search in health databases was conducted, which involved screening 248 participants across eight qualitative research studies. Themes emphasizing the importance of listening to one’s body, acknowledging hidden issues, and recognizing the impact of various factors on diabetes self-care were established. A holistic approach to self management, emphasizing the significance of positive attitudes, cultural sensitivity, and individual values in healthcare practices is recommended. Embracing cultural diversity and addressing barriers can enhance self-management and quality of life for geriatric …

What Stigmas Still Exist For Weight Loss Medications?, Abdullah Panah, Philip Collins Do

Rowan-Virtua Research Day

Background and Hypothesis:

Medications for weight loss are becoming far more common as more tolerable formulas have come to the market with some medications offering results almost on par with bariatric surgery. However, studies show a stigma still persists around the discussion and perception around using weight loss medications. The authors of this study hypothesized that one of the biggest hurdles patients face for weight loss medications are the stigmas associated with taking these medicines and approaching the topic.

Methods:

This was a survey-based project that consisted of an anonymous, voluntary questionnaire which was provided to patients during their regular …

Vitamin Level Differences Across The Asd Spectrum, Rohan Mehra, Wendy F. Aita, Andrea Iannuzzelli

Rowan-Virtua Research Day

Background: In the United States, 2.7% of children are diagnosed with Autism Spectrum Disorder (ASD). Environmental factors such as vitamin levels, including D, B9, and B12, may have a significant impact on the risk of development. Children conceived in winter months, with low sunlight and Vitamin D levels, have a higher risk of developing ASD. Vitamin B12 deficiency is generally linked with an increased risk of neurodevelopmental disorders. Additionally, vitamin B9 deficiency of a mother during gestation is linked to a higher risk of her child developing ASD.

Purpose: To assess potential differences in vitamin levels between patients of differing …

Effect Of Food Selectivity On Dyslipidemia In Autism Spectrum Disorder, Ankith Rao

Rowan-Virtua Research Day

This survey-based study sought to determine whether there is a correlation between food selectivity and blood lipid levels in autistic patients.

Exploring The Connection Between Diabetes Distress And Diabulimia, Stephen Poos, Misha Faerovitch, Celeste Pinto, Nima Jamalkhani, Fahad Chaudhri, Satara Khan, David F. Lo, Kaitlin Mcgowan, Ashaki Martin, Don D. Shamilov

Rowan-Virtua Research Day

Diabulimia is a disordered eating behavior that involves an individual with type 1 DM withholding insulin injection to lose weight. Diabetes distress, a term used to describe the psychological stress associated with managing diabetes, is believed to be the cause of this condition. This review aims to assess whether individuals with diabulimia have measurable evidence of diabetes distress. Studies that described patients qualitative experiences with Diabulimia were matched and compared to the criteria in the Diabetes Distress Scale. Over 40 of the 185 individuals across twelve studies were found to meet one or more criteria from the Diabetes Distress Scale. …

Diet Quality As Assessed By The Healthy Eating Index-2020 Among Different Smoking Status: An Analysis Of National Health And Nutrition Examination Survey (Nhanes) Data From 2005 To 2018, Ting Luo, Tung Sung Tseng

School of Public Health Faculty Publications

Background: Combining smoking with poor eating habits significantly elevates the risk of chronic illnesses and early death. Understanding of how dietary quality shifts post-smoking cessation remains limited. The objective of this study is to examine dietary quality – using Healthy Eating Index (HEI – 2020) and its 13 components, among current, former, and never smokers, and particularly the impact of quitting and the duration of cessation on dietary habits. Methods: A cross-sectional analysis of 31,569 adults from the National Health and Nutrition Examination Survey (NHANES) 2005–2018 was conducted. Dietary quality was assessed using HEI-2020 scores, which were determined by NIH …

Rapid Increase Of Female But Not Male Obesity: Analysis Of The 2023 Vanuatu Health Transition Project Survey On Aneityum, Matthew Christian, Olivia Lasalle, Zhiqiao Huang, Hannah Chen, Ricky Chen, J. Koji Lum

Binghamton University Undergraduate Journal

Globally, obesity rates are continuing to increase and countries in the midst of modernization are most vulnerable. Developing nations are undergoing a health transition alongside rapid economic modernization. The nation of Vanuatu, like other Pacific island countries, is experiencing such a transition marked by decreased cases of infectious disease and increased incidence of chronic and non-communicable diseases. Aneityum is a small and sparsely populated island in Vanuatu and is behind more developed islands in its transition. This present study is the latest in a multi-year project examining health in Vanuatu as it undergoes a health transition with an increased prevalence …

Management Of Macrovascular Diabetic Complications: A Single-Center Case Series Analysis Of Consecutively Attending Patients In Primary Care, Sanda Maria Crețoiu, Mihaela Adela Iancu, Laura Maria Condur, Teodor Salmen, Andreea Steriu, Ana Maria Alexandra Stănescu, Irina Anca Eremia, Cristina Mihaela Olariu, Eliza Elena Cinteză, Camelia Cristina Diaconu

Journal of Mind and Medical Sciences

Introduction. The prevalence of diabetes mellitus is increasing, with type 2 diabetes (T2DM) being a major health priority for any public health system. Increased arterial stiffness in patients with diabetes will lead to the appearance of vascular complications. Increased arterial stiffness in patients with diabetes usually leads to vascular complications. Any earlier diagnosis of impaired macrovascular evidence may lead to improved outcomes in patient care. The objective of our study was to assess and evaluate the finger-toe pulse wave velocity (ftPWV), as a measure of arterial stiffness, in order to assist with early detection of macrovascular diabetic complications. Materials and …

The Effects Of Sglt2 Inhibitors In Patients With Metabolic Dysfunction-Associated Fatty Liver Disease; A Narrative Review, Mihaela Simona Popoviciu, Lorena Paduraru, Mominur Rahman, Fatema Akter Supti, Roxana Adriana Stoica, Delia Reurean Pintilei, Cristina Ioana Bica, Simona Cavalu

Journal of Mind and Medical Sciences

Worldwide, metabolic dysfunction-associated fatty liver disease (MAFLD) is a significant public health concern, especially since more than fifty percent of people with type 2 diabetes are affected by it. This pathological condition includes all states of fatty liver disease, from non-alcoholic fatty liver disease (NAFLD) to steatohepatitis (NASH). Prolonged evolutions can lead to cirrhosis and cancer, so treatment must be started early. Hepatic steatosis may be improved by sodium glucose co-transporter 2 inhibitors (SGLT2 inhibitors), which prevent glucose reabsorption in the proximal renal tubule and increase urinary excretion, thus lowering plasma glucose levels. Experimental studies in animal models have suggested …

The Differences In Maternal Clean And Healthy Living Behavior In The Incidence Of Stunting In Yogyakarta, Shafa Ramadhita, Anindhita Syahbi Syagata, Nor Eka Noviani

Indonesian Journal of Public Health Nutrition (IJPHN)

An indirect cause of stunting is maternal behavior. Moreover, good nutritional knowledge relates to good nutritional behaviors. Maternal clean and Healthy Living Behavior (PHBS) in daily life can reduce the risk of infectious diseases and be role models for children in implementing their future health behavior. The study aims to investigate the differences in PHBS of mothers in the incidence of stunting ages 24-59 months in the Minggir Primary Health Center working area. The cross-sectional approach of this research was conducted from March to April 2023. The subjects of this study were 69 respondents selected by cluster random sampling. The …

Factors Associated With Wasting In Toddlers Aged 6 – 59 Months At Cimpaeun Village, Depok City, West Java, Indonesia In 2023, Early Vici Azmia, Triyanti Triyanti

Indonesian Journal of Public Health Nutrition (IJPHN)

The prevalence of wasting under five in Indonesia in 2022 is 7.7%; according to WHO, this wasting problem is a serious public health problem. Wasting is a nutritional problem in toddlers that has an impact on morbidity and mortality. The research objective was to determine the factors associated with wasting in toddlers aged 6–59 months in Cimpaeun Village in 2023. The dependent variable is wasting, and the independent variables are birth weight, history of fever, diarrhea, acute respiratory infection, energy intake, carbohydrate intake, protein intake, fat intake, mother’s age, pregnancy, mother’s education level, mother’s nutritional knowledge, and family income. This …

Relationship Of Stress And Other Factors With Emotional Eating Among Adolescents In Depok, Muthia Syifa Rahmadina, Asih Setiarini

Indonesian Journal of Public Health Nutrition (IJPHN)

Emotional eating is an overeating behavior as a coping mechanism for negative emotions that emerges in adolescence. Emotional eating causes obesity, eating disorders, and non-communicable diseases. This study aims to determine the relationship between stress, body image, peer influence, parental rearing styles, social media use, sex, sleep quality, and emotion regulation with emotional eating among adolescents at senior high school in Depok. This cross-sectional quantitative study was conducted online in March 2022. The samples were grade X and XI students from senior high school in Depok who were chosen by using purposive sampling techniques (n=174). Chi X2 test and Mann …

The Relationship Of Energy And Nutrient Intake From Eating Out And Eating At Home On Blood Hemoglobin Levels In Adolescents, Adinda Aisyah Putri, Khoirul Anwar

Indonesian Journal of Public Health Nutrition (IJPHN)

Eating out of home is a common practice in adolescents. The high frequency of eating out of home characterized by higher intakes of energy, fats, sugar, and sodium. anemia, especially iron deficiency anemia which is characterized by blood hemoglobin levels, is still a nutritional problem in Indonesia in adolescents which can have an impact on adolescent health. The aim of this study was to determine the relationship between eating out and hemoglobin levels in adolescents in Jakarta. This research is an observational study with a cross sectional research design. The subjects of this research were female students aged 15-17 years. …

Determinant Factors Of The Incidence Of Low Birth Weight In Central Java Province: Analysis Of 2018 Basic Health Research Data, Desi Irawati, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari, Fadila Wirawan

Indonesian Journal of Public Health Nutrition (IJPHN)

Low birth weight (LBW) is a global public health issue with significant short and long-term consequences for individuals and societies. This study aims to examine the most dominant risk and variations in the proportion of LBW based on fetal factors, maternal and obstetric factors, and sociodemographic factors among toddlers in Central Java Province, utilizing the 2018 Basic Health Research (RISKESDAS) data. The study used a cross-sectional study conducted on 4255 samples, utilizing univariate, bivariate (chi-square), and multivariate analysis (multiple logistic regression). Central Java has the 3rd highest number of LBW cases in Indonesia with a prevalence of 6.1%. However, univariate …

Sugar-Sweetened Beverages Consumption Based On Individual And Environmental Factors Among The Faculty Of Public Health Universitas Indonesia’S Students In 2023, Safira Diva Aranis, Wahyu Kurnia Yusrin Putra, Asih Setiarini, Teguh Jati Prasetyo

Indonesian Journal of Public Health Nutrition (IJPHN)

Sugar-sweetened beverages (SSB) are beverages that contain added sugars. Excessive consumption of SSB can have an impact on health. Some of the effects caused by SSB include obesity, fatty liver, type II diabetes, hypertension, heart disease, nutritional deficiencies, and dental caries. This research aims to determine the differences in the proportion of SSB consumption based on individual and environmental factors among students of the Faculty of Public Health UI (FPH UI) in 2023. This study uses a cross sectional design with a sample size of 194 individuals. The researcher collected data including respondent’s identities, habits of reading food labels, knowledge …

Association Between Monosodium Glutamate Consumption With Changes In Gut Microbiota And Related Metabolic Dysbiosis—A Systematic Review, Hossein Ahangari, Behnam Bahramian, Arezou Khezerlou, Milad Tavassoli, Narges Kiani-Salmi, Vahideh Tarhriz, Ali Ehsani

School of Medicine Faculty Publications

Monosodium glutamate (MSG) is used as a common food additive in some foods. However, based on our search and knowledge, no comprehensive study discussed the effect of MSG on the human gut microbiome. In this study, the effects of MSG on the gut microbiome, liver, and kidney were performed. Data were collected from databases including PubMed, Scopus, Web of Science, and ScienceDirect using the search strategy and keywords. Finally, 14 eligible studies were selected for systematic review. This study provides a new perspective on the effects of MSG on the gut flora, shedding light on the potential relationship between MSG …

Education Of The Effects Of Obesity Medications And A Stepwise Approach To Mitigate Prevalence And Encourage Lifestyle Medicine For Primary Care Physicians, Kiely M. Curran

Department of Nutrition Student Projects

My Capstone project is an Educational Manual that emphasizes a healthcare team approach to the treatment and management of obesity. The Educational Manual consists of a standardized protocol in management of obesity in patients and a document with summarized references for primary care providers; and a simplified document for patient education. There is a growing interest in the usage of obesity medications. The purpose of my Capstone project is to provide a simplified manual for the primary care provider to reference to make knowledgeable and patient-centered decisions in the prescription of obesity medications and decisions in weight-management. My methodology included …

The Impact Of Eggs On Inflammatory And Immune Profiles In Women With Polycystic Ovary Syndrome (Pcos), Clara Martin

Honors Scholar Theses

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting approximately 5-15% of women of reproductive age. Characterized by symptoms such as hyperandrogenism, ovulatory dysfunction, and insulin resistance, PCOS is also linked with significant health complications including metabolic syndrome, cardiovascular diseases, and type 2 diabetes. Recent studies highlight the critical role of immune dysfunction and chronic inflammation in exacerbating PCOS pathology, suggesting that managing these immune responses could alleviate the broader health impacts of the disorder.

Nutritional interventions, particularly those targeting immune and inflammatory pathways, have emerged as promising strategies for managing PCOS. Among various dietary components, the intake of …

Home-Based Virtual Culinary Nutrition Education Sessions For Amyotrophic Lateral Sclerosis Patients: Quantitative Experimental Pilot Study, Ciara N. Reistad, Mauricio Lobo

Department of Nutrition Student Projects

Amyotrophic lateral sclerosis (ALS) impairs voluntary muscular activity and often results in malnutrition. The need for specialized dietary therapy for ALS-related illnesses is highlighted by recent research, but it also draws attention to the lack of targeted care and ongoing nutritional status monitoring. Technological developments like telehealth and chatbots hold potential for ALS patients’ nutritional monitoring. The pilot study examined the feasibility and impact of home-based virtual culinary nutrition education sessions on nutritional knowledge, dietary intake of energy (CHO), protein (PRO) and FAT, body mass index (BMI), and functional status assessed by ALSFRS-R scores in patients with Amyotrophic Lateral Sclerosis …

Type 2 Diabetes Health Beliefs Of College Students, Emily Spindler

Honors College Theses

College students of health-related majors are sometimes assumed to have greater health literacy. The belief can be attributed to the students taking classes discussing health problems, diseases, risk factors, medical management, nutrition, and exercise. How often the health classes discuss type 2 diabetes (T2D) remains undetermined; therefore, the amount of knowledge and beliefs health students have of T2D is unknown. The objective of the study was to examine the relationship between students' majors, health beliefs about T2D, and engagement in behavioral risk factors at a mid-size regional public university. A quantitative, non-experimental, survey design was chosen, and responses were obtained …

Vitamin D Deficiency In Scheuermann's Disease Is Associated With Increased Adverse Outcomes, Shivan N. Chokshi, Srikanth Mudiganty, Rutledge Carter Clement, William Accousti

School of Medicine Faculty Publications

INTRODUCTION: Scheuermann's disease is a diagnosis of hyperkyphosis commonly encountered in pediatric patients. Studies in animal models suggest an association with vitamin D deficiency, however, extensive studies have not been performed in humans. This study analyzes the role of vitamin D deficiency on unfavorable results in patients with Scheuermann's disease. METHODS: The TriNetX database was utilized to perform a retrospective analysis. Patients in the United States aged 0-18 years with Scheuermann's disease were identified using International Classification of Diseases, Tenth Revision (ICD-10) codes and categorized into those with and without a diagnosis of vitamin D deficiency. Comparison of patient groups …

Outcomes Of Virtual Diabetes Cook Along Classes, April Litchford, Jenna Dyckman, Cindy Jenkins, Andrea Schmutz, Carrie Durward

Outcomes and Impact Quarterly

USU Extension Diabetes Cook Along classes provide diabetes education to the public while removing barriers to participation. These classes teach relevant topics through hands-on activities to increase participants’ ability to effectively self-manage their diabetes symptoms. Evaluation results show that participants experienced high satisfaction (86%) and substantial knowledge gain (92%) after the classes.

Unlocking The Therapeutic Potential Of Ellagic Acid For Non-Alcoholic Fatty Liver Disease And Non-Alcoholic Steatohepatitis, Tharani Senavirathna, Armaghan Shafaei, Ricky Lareu, Lois Balmer

Research outputs 2022 to 2026

Obesity is in epidemic proportions in many parts of the world, contributing to increasing rates of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from the initial stage of fatty liver to non-alcoholic steatohepatitis (NASH), which can progress to severe fibrosis, through to hepatocellular carcinoma. There currently exists no treatment for the long-term management of NAFLD/NASH, however, dietary interventions have been investigated for the treatment of NASH, including several polyphenolic compounds. Ellagic acid is one such polyphenolic compound. Nutraceutical food abundant in ellagic acid undergoes initial hydrolysis to free ellagic acid within the stomach and small intestine. …

Risk Of Food Insecurity Reflects Health Status In Adult Relatives Of Prek Children – ​ Data From The Steps Snap-Ed Research Study​, Lisa M B Salinas, Karla Cortez, Brenda Rodriguez, Joseph Reyes, Moises Cisneros, Elizabeth Alanis, Zasha Romero, Lin Wang, Juan C. Lopez-Alvarenga, Roberto Treviño-Peña

Research Symposium

Background: Past research shows a correlation between household food insecurity and chronic medical conditions such as diabetes in the general U.S. population as well as metabolic syndrome-related cardiometabolic markers in Hispanic/Latino youth. Furthermore, minority status, including Hispanic/Latino identity, shows an association with low food security and diabetes. The Hunger Vital Sign (HVS) is a validated screener designed to assess risk of food insecurity within households. This study analyzes associated factors related to the screener’s 2 questions, specifically targeting PreK 4-year-old children and their household relatives. The first question assesses concern about food running out before obtaining more due to financial …

Use Of A Primary Care Dataset To Describe ‘The Real Picture’ Of Diabetes In Kimberley Aboriginal Communities, Caitlyn S. White, Kimberley Seear, Lorraine Anderson, Emma Griffiths

Journal of the Australian Indigenous HealthInfoNet

Objective
Aboriginal communities are impacted by high rates of diabetes, however these are currently underestimated by national data sources used by policy and decision makers to inform allocation of health resources. We aimed to estimate diabetes prevalence and screening coverage using primary care electronic medical record data.

Methods
A cross-sectional audit was conducted using primary care data from Aboriginal regular Aboriginal Community Controlled Health Service (ACCHS) clinic attendees aged 15 years and over (n=1763) in five remote communities in the Kimberley region. Main outcome measures were overall diabetes prevalence; age-specific diabetes prevalence; prevalence of pre-diabetes; and screening rates among patients …

Balancing The Medical, Psychiatric, And Ethical Considerations In The Inpatient Treatment Of Extreme Anorexia Nervosa: A Case Report, Carter A. Schulz, Carolyn A. Kennedy

Aesculapius Journal (Health Sciences & Medicine)

Introduction: Anorexia nervosa (AN) is a psychiatric illness characterized by restricted energy intake, intense fear of gaining weight, and a disturbance in body image. A 2011 meta-analysis estimated the mortality rate for anorexia nervosa to be over 5 times that of the general population, with one-fifth of deaths in AN patients being due to suicide. Treating this disease is notoriously difficult, and treatment is complicated by these patients’ characteristically poor insight.

Case summary: Here we present the case of a 37 year old woman who visited the ED with complaints of nausea and weakness; she was admitted due to hypoglycemia, …

Scurvy: A Rare Disease Or A Rare Diagnosis?, David F. Gaieski

Department of Emergency Medicine Faculty Papers

Introduction:

Scurvy, the disease state caused by ascorbic acid deficiency, was once an extremely common disease but is now thought to be a rare disease in postmodern societies. Physicians are not trained to consider scurvy as a possible diagnosis in patients at risk; rather, it is considered a rare diagnosis to add to a differential for completeness’s sake.

Methods:

We sought to describe the scorbutic patients seen by one physician during a busy academic emergency medicine career. Case series of patients seen by one physician between 1993 and 2023 at five academic teaching hospitals with Emergency Departments (EDs) in the …

Effects Of Metformin On Glucose Metabolism And Mitochondrial Function In Patients With Obstructive Sleep Apnea: A Pilot Randomized Trial, Elizabeth R.M. Zunica, Elizabeth C. Heintz, Wagner S. Dantas, R. Caitlin Hebert, Ma Kayla Tanksley, Robbie A. Beyl, Edward C. Mader, John P. Kirwan, Christopher L. Axelrod, Prachi Singh

School of Medicine Faculty Publications

Obstructive sleep apnea (OSA) is associated with increased risk for diabetes, and standard treatment with positive airway pressure (PAP) device shows inconsistent effects on glucose metabolism. Metformin is known to treat and prevent diabetes, but its effects on skeletal muscle mitochondrial function are not completely understood. Here, we evaluate the effects of metformin on glucose metabolism and skeletal muscle mitochondrial function in patients with OSA. Sixteen adults with obesity (50.9 ± 6.7 years, BMI: 36.5 ± 2.9 kg/m2) and moderate-to-severe OSA were provided with PAP treatment and randomized to 3 months of placebo (n = 8) or metformin (n = …

Hyperkalemia: Pharmacotherapies And Clinical Considerations, Evan S. Sinnathamby, Kelly T. Banh, William T. Barham, Tyler D. Hernandez, Audrey J. De Witt, Danielle M. Wenger, Vincent G. Klapper, David Mcgregor, Antonella Paladini, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye, Giustino Varrassi

School of Medicine Faculty Publications

Hyperkalemia has been defined as a condition where a serum potassium level is > 5.5 mmol/l. It is associated with fatal dysrhythmias and muscular dysfunction. Certain medical conditions, such as chronic kidney disease (CKD), diabetes mellitus, and others, can lead to hyperkalemia. Many of the signs of hyperkalemia are nonspecific. A history and physical examination can be beneficial in the diagnosis of the condition. In this regard, certain characteristic electrocardiogram findings are associated with hyperkalemia along with laboratory potassium levels. In acute and potentially lethal conditions, hyperkalemia treatments include glucose and insulin, bicarbonate, calcium gluconate, beta-2 agonists, hyperventilation, and dialysis. There …

Severe Dysphagia With Eosinophilic Esophagitis Pattern Of Injury Related To Pembrolizumab Therapy, James S Barnett, Kevin K Yu, Xavier Rivera Rivera, Asmeen Bhatt

Faculty, Staff and Student Publications

While immune checkpoint inhibitor (ICI) therapies are effective treatments for many cancers, ICI therapies are associated with immune-related adverse events. We present a 67-year-old man with non-small cell lung carcinoma, who developed severe dysphagia with biopsies from an esophagogastroduodenoscopy showing histopathology consistent with eosinophilic esophagitis while on ICI maintenance therapy with pembrolizumab. The patient's symptoms worsened despite standard therapy. However, he had complete resolution of dysphagia symptoms once pembrolizumab was discontinued. While immune-related adverse events affecting the gastrointestinal system are increasingly recognized, ICI-associated eosinophilic esophagitis is a rare entity.