Medicine and Health Sciences Commons^™

Dietary Practices During Pregnancy In A Marshallese Community: A Mixed Methods Analysis, Britni Ayers, Cari A. Bogulski, Ashlea Bennett-Milburn, Anna Fisher, Morda Newton, Pearl A. Mcelfish

Industrial Engineering Faculty Publications and Presentations

Dietary practices during pregnancy play a pivotal role in the health of women and their children and set the foundation for long-term health. Marshallese women have disproportionally higher rates of maternal and infant health disparities, yet little is known about the dietary practices during their pregnancy. The purpose of this study was to identify dietary practices during pregnancy among Marshallese women. From March 2019 to March 2020, a purposive sample of 33 pregnant Marshallese participants participated in a mixed methods study. Two primary themes emerged: (1) traditional beliefs about a healthy diet during pregnancy; and (2) dietary change during pregnancy. …

Data-Driven Analysis Of Drug And Substance Abuse Rates Across The Varying Regions In The United States Of America, Reem Saleh

University Honors Theses

Drugs and substance abuse is one of the leading causes of death for adolescents in the United States. The consequences of using these drugs are profound and can cause both damage to one's physical and psychological health. The rates of drug abuse in the United States continue to increase over the years. This paper analyzes the trends in rates of drug abuse in the four regions in the United States. It looks at the rates in cocaine, cigarettes, marijuana, and tobacco. A preliminary analysis was done to look at the trend in rates followed by an ARIMA time series model …

An Exploration Of Health Coaching Models And Their Efficacy In Chronic Disease Management: A Literature Review, Sofia Gallamore

University Honors Theses

Amidst the rise of chronic condition prevalence in recent decades, the field of health coaching has presented itself as a feasible complementary treatment method in chronic condition prevention and management. This literature review analyzes various clinical health coaching practices and their effectiveness in improving health behaviors and clinical outcomes in patients with chronic conditions. Eight studies were compared, with particular attention directed towards the evaluation of coaching techniques and modes of delivery. It was discovered that successful health coaching practices use a combination of Motivational Interviewing (MI), self-efficacy, and goal setting. Furthermore, programs that incorporated in-person intake sessions, followed by …

Leveraging Context Patterns For Medical Entity Classification, Garrett Johnston

Computer Science Senior Theses

The ability of patients to understand health-related text is important for optimal health outcomes. A system that can automatically annotate medical entities could help patients better understand health-related text. Such a system would also accelerate manual data annotation for this low-resource domain as well as assist in down- stream medical NLP tasks such as finding textual similarity, identifying conflicting medical advice, and aspect-based sentiment analysis. In this work, we investigate a state-of-the-art entity set expansion model, BootstrapNet, for the task of medical entity classification on a new dataset of medical advice text. We also propose EP SBERT, a simple model …

Comparison Of Two Immunoassays For Detection Of Anti-Sars Cov-2 Antibodies Among Healthcare Workers At A Tertiary Referral Hospital In Nairobi, Kenya, Patrick Muriuki Mugaine

Master of Medicine in Clinical Pathology

Background: Tests for antibodies against severe acute respiratory syndrome coronavirus 2, the aetiologic agent of coronavirus disease 2019, provide evidence of past infection or immunization. At the individual level, they are useful as markers of protection against severe disease and in cases where the diagnosis by nucleic acid amplification is inconclusive. At the population level, they are an indirect measure of exposure and may be useful in monitoring changes in viral infection or uptake of immunization over time. The interpretation and optimal use of antibody assays on populations requires an appreciation of the wide variability in individual antibody responses, the …

Midwife-Led Community Transformation (Milcot) Nursing Now Challenge In Uganda, Harriet Nayika, Cliff Aliga, Lisa Bayliss-Pratt, Robert Kagwire, Grace Edwards

School of Nursing & Midwifery, East Africa

Summary

This paper describes the journey of a young African midwife utilising the Nursing Now Nightingale Challenge framework to undertake a gap analysis and a mapping exercise to provide high-quality continuous professional development education for midwives working in isolation in a deprived suburb in Uganda. The project was completed in three stages:

• Stage one mapped out the services available within Nansana, Uganda
• Stage two identified the gaps in education for midwives and nurses within the area
• Stage three developed and offered educational study days for nurses, midwives and adolescents based on the gap analysis.

Single Oral Or Single Intramuscular Dose Of Vitamin D In The Treatment Of Vitamin D Deficiency In Children At Aga Khan University Hospital, Nairobi: A Randomized Controlled Trial, Winfred Mwikali Ndaka

Master of Medicine in Paediatrics and Child Health

Background: Vitamin D deficiency is a global health concern and plays an important role in bone health and many chronic non-communicable diseases. Vitamin D deficiency in children is associated with short stature, underdevelopment, respiratory infections and many other features that increase the risk of childhood complications. The prevalence of vitamin D deficiency in Kenya among children is high. Treatment with daily oral vitamin D is associated with poor compliance. While a single high intramuscular dose vitamin D offers an alternative strategy, it is however, associated with injection site pain and its absorption is dependent on the patient’s peripheral circulation. Various …

Creative Methods For Improving Health Literacy In Underserved Communities, Grace Lance, Riley Clark, Beth Reid, Makenzie Mclauchlan, Jenny Nguyen, Kiara Maningat

Nursing Leadership in Community Engagement Projects

Creative Methods for Improving Health Literacy in Underserved Communities

In 2003, Recovery Café was founded with the goal of providing long-term recovery support to those in the margins, including those experiencing homelessness, addiction, and mental health challenges (Recovery Café, 2022). Recovery Café provides members with the support needed to gain and maintain access to housing, social and health services, healthy relationships, education, and employment (Recovery Café, 2022). Recovery Café provides this support by offering a safe space, with nutritious meals, fostering a loving community, and providing resources such as educational opportunities, 12-step meetings, and referral services (Recovery Café, 2022). In …

The Impact Of High-Anthocyanin Berry Supplementation On Cardiometabolic Markers In Humans: A Systematic Review Meta-Analysis Of Randomized Control Trials, Mia M. Abram

Master's Theses

Relevance: Heart disease is the leading cause of death worldwide. Observational and experimental evidence has shown that fruits high in polyphenols can reduce morbidity and mortality of heart disease. Introduction: This systematic review meta-analysis was conducted to evaluate the current evidence for anthocyanin-rich fruit supplementation amelioration of hypertension. Methods: Articles were identified, collected, screened, then data were analyzed via CMAv.2 for overall effect on blood pressure, nitric oxide, flow mediated dilation and pulse wave velocity. Results: The analysis showed a small, significant effect on diastolic blood pressure. No moderator groups had significant effects, though some individual subcategories showed significant effects. …

Jam – Summer 2022: One Crisis After Another…., Rafat Jan, Edwin Van Teijlingen, Kiran Mubeen

Journal of Asian Midwives (JAM)

No abstract provided.

Swot Analysis Of Community Midwifery Program In Pakistan, Bakhtawar Muhammad Hanif Khowaja, Anam Feroz, Farina Abrejo, Sarah Saleem

Journal of Asian Midwives (JAM)

The community midwifery program was launched in 2006 by the Government of Pakistan as a major initiative to provide skill birth attendance to women living in rural areas of Pakistan. The main purpose of the program is to extend maternal and newborn services to the communities, through the selection and training of community midwives (CMWs) from rural areas, and to deliver services to their local communities. However, there is a substantial difference between the number of CMWs trained and those working at their birthing stations. Therefore, this paper uses a SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis to evaluate the different …

The Psychological Toll Of Covid-19 Pandemic On Private Practice Midwives In Indonesia And Its Relation With Perceived Knowledge And Individual Adaptability, Amelia Citra Kirana, Gracia Ivonika, Dewa Ayu Mirah Ardrini, Maria Stephani Dwitya, Ratih Ibrahim, Ray Wagiu Basrowi

Journal of Asian Midwives (JAM)

COVID-19 had serious impacts on the lives and health of people across the globe. Due to the high-risk nature of their work midwives frequently report personal/professional adverse psychological impacts. However, there is a lack of studies examining the psychological impacts of the COVID-19 pandemic on private practice midwives in Indonesia and beyond. This study examines the psychological impacts of the pandemic on private practice midwives in Indonesia, as well as its association with individual adaptability and perceived knowledge about COVID-19. A total of 423 private practice midwives, who were active practitioners during the pandemic, completed an online survey, comprising five …

Hidden Relationships: Perspectives On Leadership And Management In Afghan Maternity Services - An Ethnographic Exploration, Rachel Arnold, Edwin Van Teijlingen, Kath Ryan, Immy Holloway

Journal of Asian Midwives (JAM)

Introduction: Health system leaders have a vital role to play in ensuring the delivery of high-quality care. Improving the quality of healthcare, particularly in low-income countries often focuses on the performance of healthcare providers and the availability, acceptability, and uptake of services. The role that health service leaders play in facilitating effective care has received less attention in the literature. This study explored the perspectives of Afghan maternity care providers, managers and other stakeholders on leadership and the provision of quality maternity care.
Methods: This ethnographic study used semi-structured interviews, participant observation, and background interviews for data collection. …

Verbal Inhibition Declines Among Older Women With High Fmr1 Premutation Expansions: A Prospective Study, Nell Maltman, Leann Dawalt, Jinkuk Hong, Audra Sterling, Elizabeth Berry-Kravis, Jessica Klusek, Marsha R. Mailick

Faculty Publications

The FMR1 premutation has been associated with difficulties in executive functioning, including verbal inhibition. However, little is known about the longitudinal profiles of verbal inhibition among FMR1 premutation carriers, particularly in women, and how individual factors such as aging and CGG repeat length may contribute to changes in verbal inhibition over time. The present study examined verbal inhibition performance (i.e., inhibition errors) on the Hayling Sentence Completion Task in a cohort of 92 women with the FMR1 premutation across two timepoints approximately three years apart. We examined the effects of age, CGG repeat length, and their interactions on verbal inhibition …

Dean's Update, June 2022, Jerry L. Nadler

SOM Dean's Research Newsletter

No abstract provided.

A Systematic Review Of Substance Use And Substance Use Disorder Research In Kenya, Florence Jaguga, Sarah Kanana Kiburi, Eunice Temet, Julius Barasa, Serah Karanja, Lizz Kinyua, Edith Kamaru Kwobah

Anaesthesiology, East Africa

Objectives: The burden of substance use in Kenya is significant. The objective of this study was to systematically summarize existing literature on substance use in Kenya, identify research gaps, and provide directions for future research.

Methods: This systematic review was conducted in line with the PRISMA guidelines. We conducted a search of 5 bibliographic databases (PubMed, PsychINFO, Web of Science, Cumulative Index of Nursing and Allied Professionals (CINAHL) and Cochrane Library) from inception until 20 August 2020. In addition, we searched all the volumes of the official journal of the National Authority for the Campaign Against Alcohol & Drug Abuse …

Genomic Answers For Children: Dynamic Analyses Of >1000 Pediatric Rare Disease Genomes., Ana S A Cohen, Emily G. Farrow, Ahmed Abdelmoity, Joseph Alaimo, Shivarajan Manickavasagam Amudhavalli, John Anderson, Lalit R. Bansal, Lauren E. Bartik, Primo Baybayan, Bradley Belden, Courtney D. Berrios, Rebecca L. Biswell, Pawel Buczkowicz, Orion Buske, Shreyasee Chakraborty, Warren A. Cheung, Keith A. Coffman, Ashley M. Cooper, Laura A. Cross, Tom Curran, Thuy Tien T. Dang, Mary M. Elfrink, Kendra Engleman, Erin Day Fecske, Cynthia Fieser, Keely M. Fitzgerald, Emily Fleming, Randi N. Gadea, Jennifer L. Gannon, Rose N. Gelineau-Morel, Margaret Gibson, Jeffrey Goldstein, Elin Grundberg, Kelsee Halpin, Brian S. Harvey, Bryce Heese, Wendy Hein, Suzanne M. Herd, Susan Starling Hughes, Mohammed Ilyas, Jill Jacobson, Janda L. Jenkins, Shao Jiang, Jeffrey J. Johnston, Kathryn Keeler, Jonas Korlach, Jennifer Kussman, Christine Lambert, Caitlin E. Lawson, Jean-Baptist Lepichon, J Steven Leeder, Vicki C. Little, Daniel A. Louiselle, Michael Lypka, Brittany D. Mcdonald, Neil Miller, Ann Modrcin, Annapoorna Nair, Shelby H. Neal, Christopher M. Oermann, Donna M. Pacicca, Kailash Pawar, Nyshele L. Posey, Nigel Price, Laura M B Puckett, Julio Quezada, Nikita Raje, William J. Rowell, Eric T. Rush, Venkatesh Sampath, Carol J. Saunders, Caitlin Schwager, Richard M. Schwend, Elizabeth Shaffer, Craig Smail, Sarah E. Soden, Meghan Strenk, Bonnie Sullivan, Brooke Sweeney, Jade B. Tam-Williams, Adam Walter, Holly Welsh, Aaron M. Wenger, Laurel K. Willig, Yun Yan, Scott T. Younger, Dihong Zhou, Tricia N. Zion, Isabelle Thiffault, Tomi Pastinen

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: This study aimed to provide comprehensive diagnostic and candidate analyses in a pediatric rare disease cohort through the Genomic Answers for Kids program.

METHODS: Extensive analyses of 960 families with suspected genetic disorders included short-read exome sequencing and short-read genome sequencing (srGS); PacBio HiFi long-read genome sequencing (HiFi-GS); variant calling for single nucleotide variants (SNV), structural variant (SV), and repeat variants; and machine-learning variant prioritization. Structured phenotypes, prioritized variants, and pedigrees were stored in PhenoTips database, with data sharing through controlled access the database of Genotypes and Phenotypes.

RESULTS: Diagnostic rates ranged from 11% in patients with prior negative …

Himmelfarb Library Liaison Letter - June 2022, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Liaison Letters

No abstract provided.

Framing An Interprofessional Culture Of Learning Across Healthcare Programs, Loriann Helgeson, Smokey L. Fermin, Paul Werhane, Jonathan Hook

Occupational Therapy Faculty Scholarship

Innovation Summit for Health Professions Education Virtual Conference, June 23-24, 2022: Poster Presentation: Framing an interprofessional culture of learning across healthcare programs.

Enhanced Antioxidant, Antiviral, And Anticancer Activities Of The Extract Of Fermented Egyptian Rice Bran Complexed With Hydroxypropyl-Β-Cyclodextrin, Khaled Nematallah, Sherif Ashraf Fahmy, Noha Khalil Mahdy, Hesham El-Askry, Meselhy Ragab Meselhy, Hassan El-Said Azzazy

Pharmacy

Egyptian rice bran was fermented with baker’s yeast, and released phenolics were extracted with aqueous methanol to give fermented rice bran extract (FRBE). The analysis of the FRBE with ultra-performance liquid chromatography–electrospray ionization–tandem mass spectrometry revealed 21 compounds, mainly phenolic acids and flavonoids. The FRBE was then complexed with (2-hydroxypropyl)-β-cyclodextrin (HPβCD) via noncovalent host–guest inclusion complexation using the thin-film hydration technique to improve the hydrophilicity and bioactivity of the FRBE. The formation of the inclusion complex was confirmed using HPLC, 1H NMR, FT-IR, and a phase solubility study. In addition, the biological activities of the complex were investigated. The FRBE/HPβCD …

Composition And Functional Potential Of The Human Mammary Microbiota Prior To And Following Breast Tumor Diagnosis, Courtney Hoskinson, Kelly Zheng, Jaelyn Gabel, Annie Kump, Rana German, Ram Podicheti, Natascia Marino, Leah T. Stiemsma

All Faculty Open Access Publications

Microbiota studies have reported changes in the microbial composition of the breast upon cancer development. However, results are inconsistent and limited to the later phases of cancer development (after diagnosis). We analyzed and compared the resident bacterial taxa of histologically normal breast tissue (healthy, H, n = 49) with those of tissues donated prior to (prediagnostic, PD, n = 15) and after (adjacent normal, AN, n = 49, and tumor, T, n = 46) breast cancer diagnosis (n total = 159). DNA was isolated from tissue samples and submitted for Illumina MiSeq paired-end sequencing of the V3-V4 region of the …

Hiv Antiretroviral Medication Neuropenetrance And Neurocognitive Outcomes In Hiv+ Adults: A Review Of The Literature Examining The Central Nervous System Penetration Effectiveness Score, Alyssa Arentoft, Katie Troxell, Karen Alvarez, Maral Aghvinian, Monica Rivera Mindt, Mariana Cherner, Kathleen Van Dyk, Jill Razani, Michaela Roxas, Melissa Gavilanes

All Faculty Open Access Publications

This literature review summarizes the existing research examining the CNS penetration effectiveness (CPE) score and neurocognitive outcomes (i.e., neuropsychological assessment and neurocognitive screening) in HIV+ individuals. Despite the effectiveness of Combined Antiretroviral Therapy (CART) in reducing mortality and morbidity in HIV and controlling viral replication, HIV often persists in the Central Nervous System (CNS), and rates of neurocognitive impairment remain higher than predicted in the post-CART era. The CPE score was developed to rank antiretroviral regimens on their ability to penetrate the CNS and potency in inhibiting the virus, and it has been examined in relation to neurocognitive functioning for …

Beach Chair Versus Lateral Decubitus Surgical Positioning For Arthroscopic Anterior Shoulder Stabilization: A Retrospective Comparison Of Clinical And Patient-Reported Outcomes, Ryan W Paul, Sydney Streicher, Alim Osman, Chuka Ukekwe, Usman Zareef, Kevin B Freedman, Brandon J Erickson, Sommer Hammoud, Meghan E Bishop

Rothman Institute Papers

Background: Surgical positioning can affect both perioperative and postoperative complication rates. It is unclear whether beach-chair versus lateral decubitus positioning affects outcomes in patients undergoing arthroscopic anterior shoulder stabilization surgery.

Purpose: The purpose of this study was to compare recurrent instability, complications, and patient-reported outcomes between patients who underwent arthroscopic anterior shoulder stabilization in the beach-chair versus the lateral decubitus positions. It was hypothesized that recurrent instability, complications, and patient-reported outcomes would not be affected by surgical positioning.

Study Design: Cohort study; Level of evidence, 3.

Methods: The authors reviewed the medical records of patients who underwent shoulder stabilization ( …

Preexisting Sexual Trauma And The Impacts On Psychological Well-Being Of College Students, Victoria Johnson

Dissertations

Childhood sexual abuse appears to be a taboo topic with a long history of being left out of the discussion regarding mental health in adulthood despite the varied and devastating consequences. The overall lack of research on this topic, especially regarding the college student population, can be considered a barrier to treatment for those individuals. The current literature review attempts to fill the research gap by discussing the epidemiology, prevalence, and description of preexisting sexual trauma in college students. The potential negative effects of preexisting sexual trauma and how they occur with college students were explored to highlight how pervasive …

1485-Pub: Assessing Correlates Of Microvascular Complications Among Patients With Diabetes Mellitus, Kenneth Izuora, Amalie Alver, Arpita Basu, Kavita Batra, Shelley J. Williams, Jeffrey L. Ebersole

Department of Internal Medicine Faculty Research

Background: Microvascular complications associated with diabetes (DM) are important predictors of morbidity and mortality. Understanding the factors associated with these complications is important in reducing their burden. Method: Using a cross-sectional study design, seventy-one ambulatory patients with Type 2 DM (female 60.6%, white 36.6%, mean age 64.1± 10.3 years, and mean duration of DM 15.8±9.1 years) were recruited using an investigator-administered questionnaire and chart review. Variables of demographics, smoking, HbA1c, DM duration, and complications were collected. CRP was measured and oral health status was assessed by a clinical exam. Data were analyzed using Chi-square/Fisher exact tests and binomial logistic regression …

Analysis Of Lung Cancer Screening By Race After Uspstf Expansion Of Screening Eligibility In 2021., Christine S Shusted, Nathaniel R Evans, Gregory C Kane, Hee-Soon Juon, Julie A Barta

Department of Medicine Faculty Papers

This cross-sectional study examines differences among individuals deemed eligible for lung cancer screening under USPSTF 2013 vs under USPTSF 2021 guidelines.

Finding Acute Coronary Syndrome With Serial Troponin Testing For Rapid Assessment Of Cardiac Ischemic Symptoms (Fast-Trac): A Study Protocol, W Frank Peacock, Alan S Maisel, Christian Mueller, Stefan D Anker, Fred S Apple, Robert H Christenson, Paul Collinson, Lori B Daniels, Deborah B Diercks, Salvatore Di Somma, Gerasimos Filippatos, Gary Headden, Brian Hiestand, Judd Hollander, Juan C Kaski, Joshua M Kosowsky, John T Nagurney, Richard M Nowak, Donald Schreiber, Gary M Vilke, Marvin A Wayne, Martin Than

Department of Emergency Medicine Faculty Papers

Objective: To determine the utility of a highly sensitive troponin assay when utilized in the emergency department.

Methods: The FAST-TRAC study prospectively enrolled >1,500 emergency department patients with suspected acute coronary syndrome within 6 hours of symptom onset and 2 hours of emergency department presentation. It has several unique features that are not found in the majority of studies evaluating troponin. These include a very early presenting population in whom prospective data collection of risk score parameters and the physician's clinical impression of the probability of acute coronary syndrome before any troponin data were available. Furthermore, two gold standard diagnostic …

Perceptual Flexibility For Speech: What Are The Pros And Cons?, F. Sayako Earle, Carolyn M. Quam

Speech and Hearing Sciences Faculty Publications and Presentations

How listeners handle acoustic-phonetic variability during spoken language processing is a fundamental question in the field of speech perception. A robust behavioral literature describes ways in which humans adapt their perception to accommodate idiosyncratic, or foreign-accented, speech -- or how we learn to attend to new phonetic cues, as may be important for learning a different language. And yet, we are still in the early stages of understanding the neurocognitive mechanisms that underlie group-level or individual differences in perceptual flexibility. This special issue focuses on how contextual information and acoustic-phonetic input interacts with neurocognitive factors that shape the boundaries of …

The Duration Of Spontaneous Active And Pushing Phases Of Labour Among 75,243 Us Women When Intervention Is Minimal: A Prospective, Observational Cohort Study, Ellen L. Tilden, Jonathan Snowden, Marit L. Bovbjerg, Jodi Lapidus, Melissa Cheyney, Jack Wiedrick, Aaron B. Caughey

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Friedman's curve, despite acknowledged limitations, has greatly influenced labour management. Interventions to hasten birth are now ubiquitous, challenging the contemporary study of normal labour. Our primary purpose was to characterise normal active labour and pushing durations in a large, contemporary sample experiencing minimal intervention, stratified by parity, age, and body mass index (BMI).

Methods

This is a secondary analysis of the national, validated Midwives Alliance of North America 4·0 (MANA Stats) data registry (n = 75,243), prospectively collected between Jan 1, 2012 and Dec 31, 2018 to describe labour and birth in home and birth center settings where …

Intervention Approaches For Childhood Apraxia Of Speech: An Overview Of Prevailing Treatment Methods, Toni Lewis

University Honors Theses

This paper aims to describe the theory and methods of select intervention approaches for childhood apraxia of speech so readers may better understand current treatment techniques. Covered in this paper are Rapid Syllable Transitions (ReST), Dynamic Temporal and Tactile Cueing (DTTC), Prompts for Restructuring Oral Muscular Phonetic Targets (PROMPT), as well as supplemental techniques such as augmentative and alternative communication (AAC) and ultrasound biofeedback. Also covered briefly are instances of CAS treatment in languages other than English.