Medicine and Health Sciences Commons^™

Mitochondrial Cyclophilin D Promotes Disease Tolerance By Licensing Nk Cell Development And Il-22 Production Against Influenza Virus, Jeffrey Downey, Haley E Randolph, Erwan Pernet, Kim A Tran, Shabaana A Khader, Irah L King, Luis B Barreiro, Maziar Divangahi

2020-Current year OA Pubs

Severity of pulmonary viral infections, including influenza A virus (IAV), is linked to excessive immunopathology, which impairs lung function. Thus, the same immune responses that limit viral replication can concomitantly cause lung damage that must be countered by largely uncharacterized disease tolerance mechanisms. Here, we show that mitochondrial cyclophilin D (CypD) protects against IAV via disease tolerance. CypD

Mrna Vaccine Boosting Enhances Antibody Responses Against Sars-Cov-2 Omicron Variant In Individuals With Antibody Deficiency Syndromes, Ofer Zimmerman, Alexa Michelle Altman Doss, Paulina Kaplonek, Chieh-Yu Liang, Laura A. Vanblargan, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O'Shaughnessy, Hannah G. Davis-Adams, Harry L. Bertera, Lucas J. Adams, Saravanan Raju, Fang R. Zhao, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson S. Turner, Jane A. O'Halloran, Rachel M. Presti, Daved H. Fremont, Peggy L. Kendall, Ali H. Ellebedy, Galit Alter, Michael S. Diamond

2020-Current year OA Pubs

Individuals with primary antibody deficiency (PAD) syndromes have poor humoral immune responses requiring immunoglobulin replacement therapy. We followed individuals with PAD after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination by evaluating their immunoglobulin replacement products and serum for anti-spike binding, Fcγ receptor (FcγR) binding, and neutralizing activities. The immunoglobulin replacement products tested have low anti-spike and receptor-binding domain (RBD) titers and neutralizing activity. In coronavirus disease 2019 (COVID-19)-naive individuals with PAD, anti-spike and RBD titers increase after mRNA vaccination but wane by 90 days. Those vaccinated after SARS-CoV-2 infection develop higher and more sustained responses comparable with healthy donors. …

An Investigation Into Use Of Natural Mistletoe Extracts And Their Formulations As Potential Anti-Cancer Treatments In Human Carcinomas, Rebecca Healy, Anne M. Friel

SURE Journal: Science Undergraduate Research Experience Journal

Cancer is a prevalent disease that is responsible for around 10 million deaths a year. Cases and deaths will continue to rise daily if nothing is done to find the most effective treatment. Mistletoe is an evergreen, semi-parasitic plant that grows on trees. This plant contains a number of biologically active compounds that contribute to its anti-cancer properties e.g., lectins. Mistletoe is obtained from nature and has been shown to be safe, potent, and effective in treating cancer. Herein we review the biological effects of mistletoe on cancer cells, formulations that can be used in cancer treatment and discuss the …

Effect Of Post-Activation Potentiation On The Force, Power And Rate Of Power And Force Development Of The Upper Limbs In Mixed Martial Arts (Mma) Fighters, Taking Into Account Training Experience, Alan Langer, Angelina Ignatieva, Patricia Fischerova, Magdalena Nitychoruk, Artur Gołaś, Adam Maszczyk

Baltic Journal of Health and Physical Activity

Introduction. The aim of the study is to determine the optimal load for generating the highest value of force, power and the rate of power and force development (RFD and RPD) in the upper limb of mixed martial arts (MMA) fighters with the use of activation and explosive exercises. The training period of MMA players was included in the research. Material and Methods: Twenty-nine MMA fighters participated in the study and were divided into two groups depending on the length of their training period (under and over 5 years). The subjects did 2 ballistic push-ups before the study and after-wards …

The Effect Of Caffeine On Countermovement Jump Performance In Recreationally Trained Women Habituated To Caffeine, Dawid Gawel, Magdalena Kaszuba, Zuzanna Komarek, Robert Krawczyk, Marta Bichowska, Marcin Jasinski, Robert Trybulski

Baltic Journal of Health and Physical Activity

Introduction. The main goal of this study was to examine the effect of acute intake of 3 mg/kg/body mass (b.m.) of caffeine (CAF) on countermovement jump (CMJ) performance in recreationally trained women habituated to CAF. Material and Methods. 17 healthy recreationally trained women habitually using CAF participated in the study. The experiment followed randomized, cross-over, double-blind design under three different conditions: control test (CONT) or consumed placebo (PLAC) or consumed 3 mg/kg/b.m. of CAF (CAF-3). Each participant performed 2 sets of 2 CMJ. The following variables were recorded: concentric peak velocity (PV), peak power (PP) and jump height (JH). Results. …

Relationship Between Motor Skills And Various Sailing Skills And Sports Performance – Study Using The Dematel Approach, Jedrzej Charlampowicz

Baltic Journal of Health and Physical Activity

Introduction. The purpose of this paper is to determine the mutual relation between various motor abilities and factors of sailing performance. Material and methods: 25 sailors from the Polish national team in sailing Olympic classes were asked to fill a questionnaire concerning the influence of various motor abilities and sailing performance factors on the result. In total, 5 sailors participated in the study by returning properly filled questionnaires. To determine the relationship between the motor abilities and sailing performance factors, the DEMATEL method has been utilized. Results: In terms of motor abilities, mobility is the most significant factor, and muscle …

Advancing Physiology With Expanded Multi-Omics., Mingyu Liang, Allen W Cowley, Andrew S Greene, Aron M Geurts, Pengyuan Liu, Yong Liu, Sridhar Rao

Faculty Research 2022

No abstract provided.

Improving Colorectal Cancer Screening In Primary Care, Bushra Iqbal

Doctor of Nursing Practice (DNP) Projects

Colorectal Cancer (CRC) is the second leading cause of cancer related deaths in the U.S., although it is preventable with adequate routine screening. Medically underserved minorities and immigrants require screening program awareness in their respective communities. The incidence of CRC remains markedly high despite the screening modalities among various populations. In the United States (U.S.), there were approximately 147,950 reported CRC diagnoses, 53,200 deaths, and over 35.2 cases per 100,000 in California alone reported in 2020 (Siegel et al., 2020). Healthcare providers can prevent colorectal cancer (CRC) through adequate routine screening. Various screening practices are widely implemented in primary cases …

Dna - Chemistry Of Life, Abdulrazzak Hammody Al-Qaraghuli, Ayad Ahmed Al-Taweel

Al-Esraa University College Journal for Medical Sciences

The chemical structure of DNA, RNA, telomeres, and mitochondria and their principal components are reviewed based on the type of chemical bonds and interactions between those components. This study also briefly outlines the types of chromosomes and genes in the cells of some living species, including humans. An approach regarding the polymeric nature of DNA is introduced, including the number of units or molecules in the polymer based on the unit cell dimensions of crystalline DNA material. Furthermore, the mechanism of protein synthesis inside the living cell, including the role of DNA and RNA in this process, is discussed.

Correlation Between Anatomical Variations Radiological Appearance Of Sella Turcica And Mastoid Process Density Among Cleft Palate And Non Cleft Palate Individuals, Sajad Khaldoun Al-Tamimi, Ahmed Sinan Elias, Lamia Hamid Al-Nakib

Al-Esraa University College Journal for Medical Sciences

Background: Craniofacial development is complex, and to enhance the quality of life and surgical outcomes for individuals with craniofacial anomalies, understanding the basic cell and developmental biology behind pathological craniofacial development is crucial. The aim of this study is to correlate the morphology of the Sella Turcica and mastoid process density among cleft and non-cleft Iraqi subjects. Materials and Methods: Cone-beam computed tomography images of 110 Iraqi individuals (80 with cleft palate and 30 non-cleft subjects) were automatically analyzed by a software program on a desktop computer by an expert Oral and Maxillofacial Radiologist. The Sella Turcica in the sagittal …

The Utility Of Cbct In Assessment Of Man-Dibular Bone Cortex In Osteoporotic And Non- Osteoporotic Females, Raya M. Al Bayati, Saif S. Saliem, Lamia H. Al Nakib, Maisaa Q. Mohammed Ali

Al-Esraa University College Journal for Medical Sciences

Background: Bone is a living tissue that undergoes continuous modeling and remodeling to support growth and functional demands. Variations in female hormones can impact bone quality and quantity, particularly post-menopause, increasing susceptibility to osteoporosis. This study aims to assess the effect of osteoporosis on mandibular cortical width in post-menopausal females, distinguishing it from the effects of aging using Cone Beam Computed Tomography (CBCT). Aims: The goal is to differentiate the effects of osteoporosis from aging on mandibular cortical bone using CBCT. Materials and Methods: The study included a sample group of 60 Iraqi females divided into 3 groups based on …

Prevalence Of Entamoeba Histolytica In Human From Baghdad City, Lina A. Jebur, Athmar K. Abbas

Al-Esraa University College Journal for Medical Sciences

The result of microscopic examination of 100 human stool samples showed that 33% of them were infected with Entamoeba histolytica. The rate of infection with Entamoeba histolytica in the males was 21% while in the females was 12% with a significant differences at (P6-10 years, while the lowest rate 4% was found at age group ≥20 years. The highest infection rate 54.54% occurred in July/2021, while, the lowest 18.18% was reported in January and February/2021 with significant differences at (P

Anemia And Associated Risk Factors Among Pregnant Women In Al Karkh Health Directorate, Baghdad / Iraq, Fawzi Hashim Atshan, Ibtisam Faraj Hasan

Al-Esraa University College Journal for Medical Sciences

Introduction: Anemia in pregnancy is one of the most common public health problems in developing country,it is commonly associated with poor pregnancy outcome and can result in complications that threaten the life of both mother and fetus. The main risk factors associated with anemia during pregnancy are low body storage of iron ,low intake of iron, poor absorption of iron from diet, chronic infections, and parasitic diseases . Objective: To determine the prevalence of anemia and associated risk factors among pregnant women attending antenatal care units in Baghdad Al Karkh Heath Directorate, Baghdad/Iraq . Materials and Methods: Descriptive cross-sectional study, …

Vitamin D Deficiency, Its Relation To Bone, Back Pain, Tiredness And Mood Improving In Adult Sample Collected From Baghdad City, Abass T. Al Joudi, Mohammed Raad Khalaf

Al-Esraa University College Journal for Medical Sciences

Vitamin D deficiency is a global health problem. With all the medicall advances of the century, vitamin D deficiency is still prevailing. Over a billion people worldwide are Vitamin D deficient or insufficient. In this study data collected from 58 outpatients Clinic from Bagdad citw/Iraq, suffering from Vitamin D deficiency at different rate. They were either suffer from Vitamin D deficiency (10-19) ng/ml, insufficient (20-29) ng/ml or some sutfer with sever deficiency< 10ng/ml. This study covered random samples of different gender (male and female) and from different life style, which include different symptoms (bone and back pain, tiredness, hair loss and mood improving). Results showed that women were more accessible than men for Vitamin D deficiency due to woman loss more Vitamin Dthrough menopause, pregnancy and lactation period and results showed that patients with age (40 to 59) year old and (60 to 69) year old were suffering from bone and back bone pain, were 25% of the sample study were suffering from hair loss. Most people covered in this study were felling tiredness and headache. Inthisstudy samplescollected from patients with Vitamin D deficiencies were treated by giving dosages of supplement medicine (like Cholecalciferoll and Colecaliciferol) to optimize level of 25-OH Vitamin D3. To increase Vitamin D rate in these patients. Results also showed that the supplement medicine help and improve reducing hair loss, bone and back pain within two months of taken it, were 25% of the sample study suffering from felling tiredness and headache which they start to recovered their health gradually after taken medication within first and second month of treatment. In relation to depression, it was concluded that depression was associated with low Vitamin D level in patients' especially old peoples and from the results, medical supplement found to be improves mood and reduce depression in a sample of people study especially in women.

Intouch June 20, 2022, New York Medical College

InTouch

• NYMC Honors Historic Partnership with NYC Health + Hospitals/Metropolitan During Plaque Dedication Ceremony
• COVID-19 Essentials
• Kristy Tefft, M.S. ’20, SOM Class of 2024, Puts a Premium on Patient Relationships
• The Department of Environmental Health and Safety Keeps the NYMC Community Safe and in Compliance
• Donate Life Clubs Finishes Exceptional Year With Record-Breaking Donations

A Highly Effective Natural Herbal Mixture That Helps To Normalize The Sugar Level For People With Chronic Diabetes, Isam Shaker Hamza, Aziz Latif Jarallah, Tariq Yaseen Mahmoud

Al-Esraa University College Journal for Medical Sciences

The effect of a herbal mixture consisting of (Portulaca oleracea seeds or the so-called berberine, Curcuma, Lepidium sativum seeds and Trigonella) was investi- gated as a treatment for high blood sugar. Three groups of twenty mice were used in each of these groups. The first part of this investigation was to study the chemical properties of these herbs mixture and appeared to us that this herbal mixture con- tain the following chemicals Saponins, Alkaloids, Flavonoids, Glycosides, Tannins in different proportions. The second part of the investigation concentrated on prepar- ing three groups of mice each with 20 mouse. The first …

Association Of Plasma Neurofilament Light Chain With Glycaemic Control And Insulin Resistance In Middle-Aged Adults, Rohith N. Thota, Pratishtha Chatterjee, Steve Pedrini, Eugene Hone, Jessica J. A. Ferguson, Manohar L. Garg, Ralph N. Martins

Research outputs 2022 to 2026

Aims: This study aimed to determine the association of plasma neurofilament light (NfL), a marker of neurodegeneration, with diabetes status and glycaemic parameters in people with normal glycaemia (NG), pre-diabetes (PD) and type 2 diabetes (T2D). Methods: Clinical and descriptive data for the diagnostic groups, NG (n=30), PD (n=48) and T2D (n=29), aged between 40 and 75 years were included in this cross-sectional analysis. Plasma NfL levels were analyzed using the ultra-sensitive single-molecule array (Simoa) platform. Results: A positive correlation was evident between plasma NfL and fasting glucose (r = 0.2824; p = 0.0032). Plasma NfL levels were not correlated …

Effectiveness Of Nurse-Led Volunteer Support And Technology-Driven Pain Assessment In Improving The Outcomes Of Hospitalised Older Adults: Protocol For A Cluster Randomised Controlled Trial, Rosemary Saunders, Kate Crookes, Karla Seaman, Seng Giap Marcus Ang, Caroline Bulsara, Max K. Bulsara, Beverley Ewens, Olivia Gallagher, Renee M. Graham, Karen Gullick, Sue Haydon, Jeff Hughes, Mustafa Atee, Kim Huong Nguyen, Bev O'Connell, Debra Scaini, Christopher Etherton-Beer

Research outputs 2022 to 2026

Introduction:

Hospitalised older adults are prone to functional deterioration, which is more evident in frail older patients and can be further exacerbated by pain. Two interventions that have the potential to prevent progression of frailty and improve patient outcomes in hospitalised older adults but have yet to be subject to clinical trials are nurse-led volunteer support and technology-driven assessment of pain.

Methods and Analysis:

This single-centre, prospective, non-blinded, cluster randomised controlled trial will compare the efficacy of nurse-led volunteer support, technology-driven pain assessment and the combination of the two interventions to usual care for hospitalised older adults. Prior to commencing …

Rapid Detection Of An Ebola Biomarker With Optical Microring Resonators, Abraham J Qavi, Krista Meserve, M Javad Aman, Hong Vu, Larry Zeitlin, John M Dye, Jeffrey W Froude, Daisy W Leung, Lan Yang, Frederick W Holtsberg, Ryan C Bailey, Gaya K Amarasinghe

2020-Current year OA Pubs

Ebola virus (EBOV) is a highly infectious pathogen, with a case mortality rate as high as 89%. Rapid therapeutic treatments and supportive measures can drastically improve patient outcome; however, the symptoms of EBOV disease (EVD) lack specificity from other endemic diseases. Given the high mortality and significant symptom overlap, there is a critical need for sensitive, rapid diagnostics for EVD. Facile diagnosis of EVD remains a challenge. Here, we describe a rapid and sensitive diagnostic for EVD through microring resonator sensors in conjunction with a unique biomarker of EBOV infection, soluble glycoprotein (sGP). Microring resonator sensors detected sGP in under …

Face Identity Coding In The Deep Neural Network And Primate Brain, Jinge Wang, Runnan Cao, Nicholas J Brandmeir, Xin Li, Shuo Wang

2020-Current year OA Pubs

A central challenge in face perception research is to understand how neurons encode face identities. This challenge has not been met largely due to the lack of simultaneous access to the entire face processing neural network and the lack of a comprehensive multifaceted model capable of characterizing a large number of facial features. Here, we addressed this challenge by conducting in silico experiments using a pre-trained face recognition deep neural network (DNN) with a diverse array of stimuli. We identified a subset of DNN units selective to face identities, and these identity-selective units demonstrated generalized discriminability to novel faces. Visualization …

Perceptions Of Covid-19 Self-Testing And Recommendations For Implementation And Scale-Up Among Black/African Americans: Implications For The Covid-19 Step Project, Ucheoma Nwaozuru, Thembekile Shato, Et Al.

2020-Current year OA Pubs

BACKGROUND: COVID-19 self-testing (ST) is an innovative strategy with the potential to increase the access and uptake of testing and ultimately to limit the spread of the virus. To maximize the uptake and reach of this promising strategy and inform intervention development and scale up, research is needed to understand the acceptability of and willingness to use this tool. This is vital to ensure that Black/African Americans are reached by the Biden-Harris Administration's free national COVID-19 ST program. This study aimed to explore the acceptability and recommendations to promote and scale-up the uptake of COVID-19 ST among Black/African Americans.

METHODS: …

Homotopic Contralesional Excitation Suppresses Spontaneous Circuit Repair And Global Network Reconnections Following Ischemic Stroke, Annie R Bice, Qingli Xiao, Justin Kong, Ping Yan, Zachary Pollack Rosenthal, Andrew W Kraft, Karen P Smith, Tadeusz Wieloch, Jin-Moo Lee, Joseph P Culver, Adam Q Bauer

2020-Current year OA Pubs

Understanding circuit-level manipulations that affect the brain's capacity for plasticity will inform the design of targeted interventions that enhance recovery after stroke. Following stroke, increased contralesional activity (e.g. use of the unaffected limb) can negatively influence recovery, but it is unknown which specific neural connections exert this influence, and to what extent increased contralesional activity affects systems- and molecular-level biomarkers of recovery. Here, we combine optogenetic photostimulation with optical intrinsic signal imaging to examine how contralesional excitatory activity affects cortical remodeling after stroke in mice. Following photothrombosis of left primary somatosensory forepaw (S1FP) cortex, mice either recovered spontaneously or received …

Impact Of Capsulectomy Type On Post-Explantation Systemic Symptom Improvement: Findings From The Aserf Systemic Symptoms In Women-Biospecimen Analysis Study: Part 1, Caroline Glicksman, Patricia Mcguire, Marshall Kadin, Marisa Lawrence, Melinda Haws, Jill Newby, Sarah Ferenz, James Sung, Roger Wixtrom

2020-Current year OA Pubs

BACKGROUND: Breast Implant Illness (BII) is a term used to describe a variety of symptoms by patients with breast implants for which there are no abnormal physical or laboratory findings to explain their symptoms. There currently exists a difference of opinion among clinicians and patients concerning the diagnosis and treatment of patients self-reporting BII.

OBJECTIVES: The first aim of this study was to determine if there is a valid indication for "en bloc" capsulectomy in patients self-reporting BII and if the type of capsulectomy performed alters long-term symptom improvement. The second goal was to identify any clinical laboratory differences between …

Abuse Of Benzodiazepines Among The Elderly Population, Sofia A. Padilla

College of Pharmacy Student Research

Throughout the years, benzodiazepines are safe drugs to treat several conditions among the elderly population, including anxiety, mixed anxiety-depression, and insomnia. However, inappropriate use of this drug, together with known risks such as cognitive impairment, delirium, and falls, is on the rise in these recent years, making the elderly population more inclined to suffer adverse effects when using them. The literature review paper will examine the use of benzodiazepines among the elderly population and their abuse through various published articles that addressed these concerns. The paper will also examine some potential solutions that will reduce the inappropriate use of benzodiazepine …

Genetics Education In Primary Care Residency Training: Satisfaction And Current Barriers, Nadia Falah, Amna Umer, Emilea Warnick, Manuel Vallejo, Timothy Lefeber

Faculty & Staff Scholarship

Background

Genetics education can be integrated into general care medicine through primary care residency programs. A study of primary care residents was done to evaluate quality, satisfaction, and barriers in genetics education in residency training programs. Thus, providing more evidence for the necessity for its development and progress.

Methods

A cross-sectional descriptive self-administered questionnaire survey was delivered to four primary care West Virginia University (WVU) residency training programs in 2020–2021. The anonymous 14-item survey included the following questionnaire domains: general data, genetics training satisfaction, and genetics education barriers.

Results

The survey response rate was 52% (70/123) and 59 participants completed …

Promoting Cancer Health Equity: A Qualitative Study Of Mentee And Mentor Perspectives Of A Training Program For Underrepresented Scholars In Cancer Health Disparities, Anastasia Rogova, Isabel Martinez Leal, Maggie Britton, Shine Chang, Kamisha H Escoto, Kayce D Solari Williams, Crystal Roberson, Lorna H Mcneill, Lorraine R Reitzel

Faculty, Staff and Student Publications

Racial and ethnic minorities, and women, experience stark disparities in cancer risk behaviors and mortality rates, yet often remain underrepresented in scientific research positions. We conducted an exploratory, qualitative study to examine the value of mentored research experience as part of an NCI-funded research training program designed to increase the representation of minority and women scientists in cancer disparities research. Using individual interviews, we explored 16 mentees' and 7 mentors' program experiences and perspectives to identify the most effective strategies to build strong mentoring relationships that could ultimately contribute to increased representation in health disparities research. Two expert analysts employed …

An Exploratory Analysis Of Gait Biomechanics And Muscle Activation In Pregnant Females With High And Low Scores For Low Back Or Pelvic Girdle Pain During And After Pregnancy, Jennifer J. Bagwell, Nicholas Reynolds, Jo Armour Smith, Michelle Walaszek, Hannah Runez, Kristina Lam, Julie Peterson, Dimitrios Katsavelis

Physical Therapy Faculty Articles and Research

Background

The purpose of this study was to compare gait kinematics, kinetics, and muscle activation between pregnant females with high and low scores for low back and/or pelvic girdle pain during and after pregnancy.

Methods

Twenty participants tested during second trimester, third trimester, and again post-partum. At each session, motion capture, force plates, and surface electromyography data were captured during self-selected velocity over-ground walking. Participants completed the Quebec Back Pain Disability Scale (QBPDS) and were assigned to high (QBPDS ≥15) or low pain groups (QBPDS

Findings

Nine participants met the high pain group criteria and 11 were low pain. During …

Stroke Recovery Phenotyping Through Network Trajectory Approaches And Graph Neural Networks, Sanjukta Krishnagopal, Keith Lohse, Robynne Braun

2020-Current year OA Pubs

Stroke is a leading cause of neurological injury characterized by impairments in multiple neurological domains including cognition, language, sensory and motor functions. Clinical recovery in these domains is tracked using a wide range of measures that may be continuous, ordinal, interval or categorical in nature, which can present challenges for multivariate regression approaches. This has hindered stroke researchers' ability to achieve an integrated picture of the complex time-evolving interactions among symptoms. Here, we use tools from network science and machine learning that are particularly well-suited to extracting underlying patterns in such data, and may assist in prediction of recovery patterns. …

Outcome Predictors In Catheter Interventions For Severe Right Ventricular Outflow Tract Obstructions, Sonia A. El-Saiedi, Wael A. Attia, Ashraf Abdelrahim, Baher M. Hanna

Journal of the Saudi Heart Association

Introduction & Aim of Work: Transcatheter treatment for critical pulmonary stenosis and membranous pulmonary atresia has become the gold standard of care in many centers. We aimed at evaluating the predictors of outcome in interventions for treatment of duct-dependent right ventricular outflow tract obstruction with intact interventricular septum. Subjects & Methods: 68 cases with pulmonary atresia with intact interventricular septum (PA/IVS) and 50 cases with critical pulmonary stenosis (CPS), all younger than 3 months of age, were operated during the period of 10 years; excluding patients with tricuspid valve annulus Z-score smaller than -4, evidence of right ventricular-dependent coronary circulation …

Improving Chronic Illness Self-Management With The Apsáalooke Nation: The Báa Nnilah Project, A Cluster Randomized Trial Protocol, John Hallett, Du Feng, Alma Knows His Gun Mccormick, Sarah Allen, Jillian Inouye, Mark Schure, Shannon Holder, Lucille Other Medicine, Suzanne Held

Nursing Faculty Research

Chronic illness (CI) is a major cause of morbidity and mortality for Indigenous people. In Montana, Indigenous communities disproportionately experience CI, a legacy of settler colonialism. For over two decades, Messengers for Health, an Apsáalooke (Crow Indian) non-profit, and Montana State University have partnered to improve community health using a community-based participatory research (CBPR) approach. We developed Báa nnilah, an intervention utilizing community strengths, to improve CI self-management. This manuscript describes the protocol for a cluster randomized trial with two arms: an intervention group and a wait list control group, who both participated in the Báa nnilah program. Enrollment occurred …