Medicine and Health Sciences Commons^™

Prenatal Education For Black Mothers And Their Support Persons As An Intervention For Improving Initiation Of Breastfeeding, Sandra King

Doctor of Nursing Practice Projects

Background: The benefits of breastfeeding are commonly known; however, the rates of exclusive breastfeeding among the Black community are less than those of other ethnic groups. Providing breastmilk or formula to an infant is an individual decision. Influential factors such as cultural background, employment status, socioeconomic status, level of education, and availability of support from family members and health care providers correlate with the method a mother chooses to feed her infant. Increasing breastfeeding initiation immediately after birth is a necessary precedent for uptake in the exclusivity of breastfeeding.

Purpose: This Doctor of Nursing Practice project aims to improve prenatal …

Implementation Of A Diabetes Self-Management Education Program In The Rural Health Care Setting To Improve Glycemic Control In The African American Adult Population, Patricia Jackson

Doctor of Nursing Practice Projects

Background: According to the Center for Disease Control (CDC), Type 2 Diabetes Mellitus (T2DM) is a significant epidemic health problem worldwide. Furthermore, with the generality of T2DM-associated complications increasing, individuals living with chronic diseases must be competent in self-management to prevent long-term complications (CDC, 2021). Therefore, this Project Investigator aims to decrease the reported home glycemic control and improve diabetes self-management education among African American individuals in rural healthcare using the DSMEP tool.

Purpose: The purpose of the DNP project was to implement and assess the Diabetes Self-Management Education Program (DSMEP) effect on African American individuals in the rural health …

Stroke Care: Achieving Recommended Door To Computed Tomography Times In Ambulatory Patients Presenting To The Emergency Department Of A Rural Hospital Through The Application Of American Stroke Association Guidelines, Ricardo Paitz

Doctor of Nursing Practice Projects

Background: Time matters in stroke care, and every second counts because the extent of irreversible neuronal damage increases over time (Saver, 2006). Therefore, the American Stroke Association (ASA) recommends a door to computed tomography time of 20 minutes or less for patients presenting with signs of acute ischemic stroke. This time metric in stroke care is often not met, resulting in the delay of care of patients which translates to poorer outcomes, including death and a decreased quality of life in patients who have suffered an acute ischemic stroke (Kamal, Sheng, et al., 2017).

Purpose: The purpose of this DNP …

Utilization Of Staff Education To Improve The Management Of Aggression And Violence In The Rural Inpatient Psychiatric Setting, Clara Ugwuibe-Ogunseye

Doctor of Nursing Practice Projects

Background: Workplace violence (WPV) is a global concern and an occupational hazard faced by healthcare professionals worldwide. Aggression and violence can result in serious injury to the patient, healthcare professional, other patients, or visitors and cause stress to healthcare workers, and increase work absences (Picot, 2021).

Purpose: This DNP process improvement project aim was to utilize an educational training program on violence risk assessment, therapeutic communication, and verbal de-escalation techniques, to improve the confidence of mental health nursing staff in using early intervention to manage aggressive, violent patients. This education and early intervention reduced rates of aggression and violence escalation, …

Reducing Admissions Of Adult Congestive Heart Failure Patients In The Acute Care Setting, Jamekia Calhoun

Doctor of Nursing Practice Projects

Background: Heart failure (HF) is a clinical diagnosis that affects about 1 to 2% of the population worldwide. Poor education regarding self-care behaviors after discharge has contributed to increased readmissions after acute hospitalization. Hospital readmissions cost is approximately one hundred thousand dollars. This increase in cost has forced the Centers for Medicare and Medicaid Service (CMS) to place penalties on organizations with high readmission rates. The organization may be penalized for increases in readmission rates by decreasing the percentage of the combined total Medicare payments received from the CMS (Centers for Medicare and Medicaid Services [CMS], 2021)

Purpose: …

Implementation And Evaluation Of A Post-Op Coronary Artery Bypass Graft Extubation Checklist To Reduce Prolonged Intubation In The Intensive Care Unit, Melissa Bailey

Doctor of Nursing Practice Projects

Background: Total intubation time of post-op coronary artery bypass graft (CABG) patients is set by the Society of Thoracic Surgeons (STS) guidelines. STS states that post-op CABG patients need to be extubated within twelve hours of end anesthesia time with a recommendation of fewer than six hours. The project site had a total intubation time of greater than seventeen hours before removing the outliers. The current process does not result in a total intubation time of fewer than six hours. Implementation of an extubation checklist was chosen as the intervention for this DNP project.

Purpose: This DNP project aims to …

Analysis Of Neonatal Neurobehavior And Developmental Outcomes Among Preterm Infants., Elisabeth C. Mcgowan, Julie A. Hofheimer, T Michael O'Shea, Howard Kilbride, Brian S. Carter, Jennifer Check, Jennifer Helderman, Charles R. Neal, Steve Pastyrnak, Lynne M. Smith, Marie Camerota, Lynne M. Dansereau, Sheri A. Della Grotta, Barry M. Lester

Manuscripts, Articles, Book Chapters and Other Papers

Importance: The ability to identify poor outcomes and treatable risk factors among very preterm infants remains challenging; improving early risk detection and intervention targets to potentially address developmental and behavioral delays is needed.

Objective: To determine associations between neonatal neurobehavior using the Neonatal Intensive Care Unit (NICU) Network Neurobehavioral Scale (NNNS), neonatal medical risk, and 2-year outcomes.

Design, Setting, and Participants: This multicenter cohort enrolled infants born at less than 30 weeks' gestation at 9 US university-affiliated NICUs. Enrollment was conducted from April 2014 to June 2016 with 2-year adjusted age follow-up assessment. Data were analyzed from December 2019 to …

Automatic Information Extraction From Childhood Cancer Pathology Reports, Hong Jun Yoon, Alina Peluso, Eric B. Durbin, Xiao Cheng Wu, Antoinette Stroup, Jennifer Doherty, Stephen Schwartz, Charles Wiggins, Linda Coyle, Lynne Penberthy

School of Medicine Faculty Publications

Objectives: The International Classification of Childhood Cancer (ICCC) facilitates the effective classification of a heterogeneous group of cancers in the important pediatric population. However, there has been no development of machine learning models for the ICCC classification. We developed deep learning-based information extraction models from cancer pathology reports based on the ICD-O-3 coding standard. In this article, we describe extending the models to perform ICCC classification. Materials and Methods: We developed 2 models, ICD-O-3 classification and ICCC recoding (Model 1) and direct ICCC classification (Model 2), and 4 scenarios subject to the training sample size. We evaluated these models with …

Association Of Obesity And Diabetes With The Incidence Of Breast Cancer In Louisiana, Fokhrul M. Hossain, Denise M. Danos, Qiufan Fu, Xinnan Wang, Richard A. Scribner, San T. Chu, Ronald L. Horswell, Eboni G. Price-Haywood, Bridgette M. Collins-Burow, Xiao Cheng Wu, Augusto C. Ochoa, Lucio Miele

School of Medicine Faculty Publications

Introduction: Breast cancer is a heterogeneous disease, consisting of multiple molecular subtypes. Obesity has been associated with an increased risk for postmenopausal breast cancer, but few studies have examined breast cancer subtypes separately. Obesity is often complicated by type 2 diabetes, but the possible association of diabetes with specific breast cancer subtypes remains poorly understood. Methods: In this retrospective case-control study, Louisiana Tumor Registry records of primary invasive breast cancer diagnosed in 2010–2015 were linked to electronic health records in the Louisiana Public Health Institute's Research Action for Health Network. Controls were selected from Research Action for Health Network and …

Variation In The Hemoglobin Glycation Index, James M. Hempe, Daniel S. Hsia

School of Medicine Faculty Publications

A high hemoglobin glycation index (HGI) has been repeatedly associated with greater risk for hypoglycemia in people with diabetes and greater risk for chronic vascular disease in people with or without diabetes. This review explores how different sources of analytical and biological variation in HbA1c and blood glucose individually and collectively affect the clinical information value of HGI. We conclude that HGI is a complex quantitative trait that is a clinically practical biomarker of risk for both hypoglycemia and chronic vascular disease.

Hippo Signaling Pathway: A Comprehensive Gene Expression Profile Analysis In Breast Cancer, Hassan Yousefi, Mahsa Rostamian Delavar, Fatemeh Piroozian, Masoud Baghi, Khoa Nguyen, Thomas Cheng, Cecilia Vittori, David Worthylake, Suresh K. Alahari

School of Medicine Faculty Publications

Breast cancer (BC) is the most frequently diagnosed malignancy in women and a major public health concern. The Hippo pathway is an evolutionarily conserved signaling pathway that serves as a key regulator for a wide variety of biological processes. Hippo signaling has been shown to have both oncogenic and tumor-suppressive functions in various cancers. Core components of the Hippo pathway consist of various kinases and downstream effectors such as YAP/TAZ. In the current report, differential expression of Hippo pathway elements as well as the correlation of Hippo pathway mRNAs with various clinicopathologic characteristics, including molecular subtypes, receptor status, and methylation …

Effect Of Vision Therapy On Post Concussion Metrics On The Graded Symptom Checklist, Justin Pasquale, Joseph Pasquale, Eden Hunt, David Clark, Daniele Shollenberger, Mark Cipolle Md

Research Scholars

No abstract provided.

Physical Activity And Breast Cancer Prevention Among Asian American Women, Jingxi Sheng

Theses and Dissertations

Asian Americans (AsAm) comprise about 7% of the United States population and are the only racial group for whom cancer is the leading cause of death. Breast Cancer (BrCa) is the most commonly diagnosed cancer in this population, with the highest incidence in the age of 45-49 years, which is 30 years younger than for non-Hispanic Whites. The incidence of BrCa has been increasing for over three decades in AsAm.

Physical activity (PA) is a modifiable protective factor for BrCa. Unfortunately, AsAm women have a low PA prevalence of meeting PA recommendations. The increased BrCa risk, younger age at diagnosis, …

Comparing Lvhn Standard Of Care Equipment And Delfin Technologies Equipment For Burn Scar Assessment, Charlotte Samuelson, Sigrid A. Blome-Eberwein Md

Research Scholars

No abstract provided.

Evaluating The Effectiveness Of Providing Social And Medical Resources To Recently Discharged Patients Experiencing Malnutrition, Theresa Tellez, Melissa Faura Rd, Ldn, Ann Flickinger Ms, Rd, Ldn, Kimberly Procaccino Mba, Rd, Ldn

Research Scholars

No abstract provided.

Drive Leg Ground Reaction Forces And Rate Of Force Development Over Consecutive Windmill Softball Pitches, Erin R. Pletcher, Kenzie B. Friesen, Gretchen D. Oliver, Mita Lovalekar, Keith Gorse, Takashi Nagai, Chris Connaboy

Department of Exercise Science Faculty Papers

BACKGROUND: Windmill softball pitching is a highly skilled movement, combining whole body coordination with explosive force. Successful pitching requires sequential movement to transfer energy produced by the lower extremity to the pitching arm. Therefore, drive leg ground reaction force (GRF) and the time over which a pitcher can develop force during push off, defined as rate of force development (RFD), is essential for optimal performance. The aim of this study was to examine GRF and RFD in the drive leg during the windmill softball pitch, as well as pitch velocity, throughout a simulated game.

METHODS: Fourteen softball pitchers (17.9±2.3 years, …

Association Between Suicide Rate And Human Development Index, Income, And The Political System In 46 Muslim-Majority Countries: An Ecological Study, S. M. Yasir Arafat, Marthoenis Marthoenis, Murad Khan, Mohsen Rezaeian

Brain and Mind Institute

Very little has been researched assessing the relationship between the suicide rate and the ecological perspectives of the country, especially in the Muslim majority countries. We aimed to determine the association between suicide rate and the ecological parameters of 46 Muslim majority countries. We extracted the Muslim majority countries and their suicide rate, income distribution, distribution of the WHO region and continents, and Human Development Index (HDI). We assessed the correlation of the proportion of Muslim populations, the total population of the countries, number of suicides, continent, income group, political system, and HDI score with the suicide rate. The median …

Clinical Experience During The Covid-19 Pandemic: Student Nurses Perspectives, Vinita Rosa Monis, Aksa Rajan David, Radhika R. R Pai, Linu Sara George

Manipal Journal of Nursing and Health Sciences

Covid 19 pandemic spread in India has affected the teaching-learning aspects of academics. (Raja & Lakshmi Priya, 2022) 290 million students out of school due to COVID-19: UNESCO releases first global numbers and mobilizes response. (UNESCO, 2020) All educational institutions in the country were immediately shut down and all students were sent back to their respective homes as soon as the rise in covid 19 cases was detected (Mid-March 2020). (Tarkar, 2020) BSc Nursing program in India has compulsory requirements for completion of practical requirements before the course completion. (Nursing Council) Clinical postings were withheld during the peak of the …

Feto-Maternal Outcomes Of Pre-Eclampsia: A Retrospective Study, Linda Varghese, Neenumol Babu, Niya V.C

Manipal Journal of Nursing and Health Sciences

Introduction: Pre-eclampsia is a multisystem multifactorial disease unique to pregnancy with unknown aetiology which is characterized by blood pressure ≥140/90 mmHg after 20 weeks of gestation associated with proteinuria ≥300 mg/24- hour urine specimen. It complicates about 2-10% of pregnancies worldwide. Objectives: To determine the prevalence and evaluate feto-maternal outcomes of pre-eclampsia. Methods: This was a retrospective study conducted at Amrita Institute of Medical Sciences, (AIMS) Kochi from 1 August 2017 to 31 July 2018. This study was done by retrospective analysis of the delivery register (Labour room) and hospital medical records. Results: The prevalence of pre-eclampsia is 2.5% and …

Formulations And Evaluation Of Mucoadhesive Buccal Tablets Of Anti-Histamine Drug Using Natural Polymers, Shardor Ambarish Ghalappa Shardor Mr, Siddramappa Basavaraj Shirsand Dr, Shailashri Siddramappa Shirsand Mrs, Chandrakant C. Patil Dr

Manipal Journal of Nursing and Health Sciences

Introduction: The present investigation highlights the formulation of buccoadhesive tablets of Ketotifen fumarate, a second-generation H1-antihistamine and mast cell stabilizer. The properties of Ketotifen may contribute to its antiallergic activity. Method: The mucoadhesive buccal tablets of Ketotifen fumarate were prepared by direct compression method using natural polymers like sodium alginate, xanthan gum, karaya gum, and gaur gum along with carbopol 934P in different ratios. Ethyl cellulose is used as a backing layer to promote the unidirectional flow of drugs in the buccal region. Results: After examining the flow properties of the powder blends the results were found to be within …

Palliative Stenting Of The Venous Duct In A Premature Neonate With Obstructed Infradiaphragmatic Total Anomalous Pulmonary Venous Connection, John S. Lozier, Martin L. Bocks

Faculty Scholarship

In infracardiac, infradiaphragmatic total anomalous pulmonary venous connection, all four pulmonary veins connect to a descending vertical vein that usually drains to the portal vein or one of its tributaries. Obstruction is common, and definitive treatment is surgical repair. We present a case of late-diagnosed infradiaphragmatic total anomalous pulmonary venous connection in a premature neonate who was too high risk for surgery and underwent palliative stenting of the venous duct. We demonstrate the feasibility of a transhepatic approach when umbilical access is no longer available.

The Paradoxical Effects Of Covid-19 Event Strength On Employee Turnover Intention, Hui Deng, Wenbing Wu, Yihua Zhang, Xiaoyan Zhang, Jing Ni

All Faculty Open Access Publications

As a global pandemic, the novel coronavirus (COVID-19) has brought enormous challenges to employees and organizations. Although numerous existing studies have highlighted that the COVID-19 pandemic is a stressful event and empirically proved its detrimental effect on employee turnover intention, few scholars have noted that this pandemic can deteriorate the external economic and employment environment simultaneously, which may further complicate employees’ intentions to leave or stay in the current organization. Drawing on event system theory and social cognitive theory, this study aims to uncover two potential cognitive mechanisms of the complex impact of COVID-19 event strength on employee turnover intention. …

Does Public Health Start Within Jails? A New Incentive For Reform Of Wisconsin's Bail System, Mahmood N. Abdellatif

Marquette Law Review

Wisconsin’s Milwaukee and Dane Counties are among many jurisdictions in the country employing modern bail reforms, specifically the Public Safety Assessment (PSA). Most of these jurisdictions adopted the PSA before the advent of the COVID-19 pandemic in the United States, but are increasingly relevant as the virus continues to derail public health measures. Through the intersection of detainees, correctional officers, judicial officials, attorneys, and visitors, millions of Americans filter in and out of correctional facilities on an annual basis. These facilities serve as a microcosm of society and breeding ground for mass infection. The COVID-19 pandemic amplified an existing need …

Depression In Male Patients With Schizophrenia Residing In Half-Way House For Protection And Development Of Mental Disabilities, Pathum Thani Province, Soraya Nabun, Chavit Tunvirachaisakul

Chulalongkorn Medical Journal

Background: Schizophrenia is a mental disorder with prominently impaired cognitive ability and daily life functioning, resulting in institutionalization for some patients A common comorbidity of patients with schizophrenia is depression that could further reduce patients quality of life. Objectives: The current study aimed to examine the prevalence of depression and associated factors in male patients with schizophrenia residing at Half-way House for Protection and Development of Mental Disabilities, Pathum Thani Province. Methods: This cross-sectional descriptive study was conducted among patients with schizophrenia who was residing at the half-way house. The data collection period for all eligible patients was from September …

Incidence And Imaging Pattern Of Stroke After Cardiac Surgery, Saruda Vichitpunt, Netsiri Dumrongpisutikul

Chulalongkorn Medical Journal

Background: Few cases of patients of previous studies have provided information on imaging patterns of stroke after cardiac surgery. Objective: The purpose of this study was to determine the incidence and imaging pattern of stroke after cardiac surgery according to type of cardiac surgery. Methods: A retrospective observational study was conducted on 3,645 adult patients who underwent cardiac surgery in cardiovascular thoracic unit at our institute from January 1, 2010 – September 30, 2019. Cases of patients who were suspected of having post-operative stroke and on whom brain imaging had been performed were reviewed. The ischemic stroke was categorized into …

Parents’ Knowledge And Attitudes Toward Usage Of Digital Screen Devices In 6-Month-Old To 5-Year-Old Children In Thailand, Wiwat Angkittisawat, Napakkawat Buathong, Pantri Kirdchok

Chulalongkorn Medical Journal

Background: Because 6-month-old to 5-year-old children cannot control their behavior of using digital screen devices on their own and control and supervision from parents are required, parents’ knowledge toward proper usage of digital screen devices in children is necessary. Objective: This study aimed to investigate parents’ knowledge and attitudes toward usage of digital screen devices in 6-month-old to 5-year-old children in Thailand. Methods: This was a cross-sectional descriptive study. The data were collected from 954 samples of parents of 6-month-old to 5-year-old children in Thailand. They volunteered to answer the online questionnaire between April – June 2019. Results: Most parents …

A Comparison Of Dilatation Of The Right Atrium On Post Mortem Ct Between Asphyxial Death And Non-Asphyxial Death, Irada Jhunthasiriyakorn, Koravik Meesilpavikkai, Udomsak Hoonvijit, Rathachai Kaewlai, Raksachai Nathongchai

Chulalongkorn Medical Journal

Background: The dilatation of the right atrium and the great vein is one of classical Sign of asphyxial death. The diagnosis of dilatation of the right atrium from the autopsy is difficult due to the unclear criteria and unavailability of measuring the organ size while it is still in the body. Post-mortem computed tomography (PMCT) is useful for the study on the dilatation of the right atrium before autopsy. Objective: This study aimed to compare the size of right atrium measuring with PMCT between the asphyxial and non-asphyxial death. Methods: The samples of this observational analytic research were a total …

Meaning Of Life And Its Association With Perspective Towards Life And Way Of Living: A Qualitative Study In Palliative Care Professionals, Soonthorn Limluck, Wiraporn Pothisiri, Teerayuth Rungnirundorn

Chulalongkorn Medical Journal

Background: Having the meaning of life plays an essential part in human life. It is shown to affect one’s perspective towards life and way of living, and is positively correlated with physical and mental health status. However, the meaning of life in palliative care staff was not yet explored. Objectives: This study aimed to uncover the meaning of life among the palliative care professionals, and to determine factors contributing to the meanings. The associations between the meaning of life and their professions and the way of life were also studied. Methods: Qualitative descriptive method was employed. Twelve palliative care professionals …

Effect Of Injury Mechanism And Severity On The Molecular Pathophysiology Of Traumatic Brain Injury, Brandon Mcdonald

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Traumatic brain injury (TBI) mechanism and severity are heterogenous clinically, resulting in a multitude of physical, cognitive, and behavioral deficits. However, approximately 80% suffer from milder injuries. Thus, examining pathophysiological changes associated with mild TBI is imperative for improving clinical translation and evaluating the efficacy of potential therapeutic strategies. Through this work, we developed models of TBI, ranging in both injury mechanism and severity, using an electromagnetic controlled cortical impact (CCI) device. First, we characterized and optimized a closed head, mild TBI model (DTBI) to determine the clinical translatability and practicality of producing repeated mild injuries. Interestingly, we determined that …

Precision Dentistry In Practice, Diana V. Macri

Publications and Research

A paradigm shift is necessary to improve healthcare delivery and outcomes. Precision medicine and precision dentistry may be able to shift the burden of disease and improve the nation’s oral and overall health.