Medicine and Health Sciences Commons^™

Parents' Knowledge, Attitude And Practices Toward Oral Health Of Their Children With Primary Dentition: A Cross Sectional Study, Marwa Foad, Mennatallah Helal, Soad Abdel Moneim

Journal of Medicine in Scientific Research

Objective This cross-sectional study aims to assess parents' knowledge, attitude, and practices toward the oral health of their children with primary dentition. Patients and methods The study was performed in the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University. Data were obtained through 301 questionnaires translated from English to Arabic, for the assessment of the parents' knowledge, attitude, and practices scores and via clinical examination of the children for the assessment of caries prevalence by calculation of their dmf scores. Results The majority of parents (90%) had adequate knowledge scores with a significantly strong negative correlation …

Anatomical Changes And Ovarian Reserve Assessment Following Methotrexate Therapy In Tubal Ectopic Pregnancy, Ayman S. Dawood, Hesham M. Borg, Mona K. Omar

Journal of Medicine in Scientific Research

Background Methotrexate (MTX) therapy for ectopic pregnancy (EP) is widely used as an alternative for surgical treatment. Its effects on ovarian reserve or pelvic anatomy are not well established. Aims The aim was to evaluate anatomical changes and ovarian reserve in cases of tubal EP treated by MTX therapy. Materials and methods A prospective cohort study was conducted at Tanta University. All patients with EP were enrolled. Eligible patients were treated by MTX. Ovarian reserve was assessed by anti-Mullerian hormone (AMH) level and antral follicle count (AFC) 3 months after treatment. Anatomical changes were assessed by laparoscopy 6 months after …

The Use Of Two 90-Degree Arc Intracorneal Ring Segments In Management Of Crab-Claw Topographic Pattern, Hazem A. Elnashar

Journal of Medicine in Scientific Research

Background Keratoconus and pellucid marginal degeneration (PMD) are bilateral, progressive, and ectatic corneal disorders characterized by thinning of the cornea. Aim To assess the visual and refractive outcome of using two 90-degree arc intrastromal corneal ring segments (ICRS) in the management of crab-claw topographic pattern. Patients and methods This study included 17 eyes of nine patients with crab-claw topographic patterns, either pellucid-like KC or PMD, needing ICRS. Preoperative evaluation included detailed ocular history, full ophthalmic examination, including uncorrected visual acuity (UCVA), manifest refraction, best spectacle-corrected visual acuity, and Pentacam. Results Regarding visual outcome, the mean UCVA improved significantly from 0.12 …

Effect Of Photorefractive Keratectomy Versus Laser In Situ Keratomileusis On Corneal Hysteresis In Moderate Myopic Eyes, Hussam Eldeen O. Elrashidy

Journal of Medicine in Scientific Research

Introduction Ablation procedures used for vision correction such as photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK) flap creation produce massive changes within the corneal structure and biomechanical properties. These changes are due to thinning of the central cornea and disruption of continuity of the collagen lamellae. Several approaches to assessment of the biomechanical properties have been proposed. Refractive photoablation procedures that decrease corneal hysteresis (CH) and corneal resistance factor (CRF) have been shown by several studies; therefore, here in our study we are going to discuss the effect of PRK versus LASIK on the corneal biomechanics and stability …

Optical Coherence Tomography Angiography In Comparison With Fluorescein Angiography In Diabetic Retinopathy, Ghada Samir, Hussam E. O. Elrashidy

Journal of Medicine in Scientific Research

Background Diabetic retinopathy (DR) is a microvascular complication of diabetes, and it is a leading cause of blindness. Fluorescein angiography (FA) is a vitally crucial diagnostic tool for evaluating fundus features of diabetic retinopathy. Purpose The purpose of the study was to evaluate optical coherence tomography angiography (OCTA) in eyes with diabetic maculopathy (DM) compared with the findings in fundus fluorescein angiography. Design It is a cross-sectional study. Patients and methods The study involved 40 eyes of 40 patients suffering from DM. The patients' ages ranged from 30 to 66 years with a mean value of 51.4 ± 8.55 years, …

Comparative Study Between Medial Rectus Slanting Versus Medial Rectus Faden With Or Without Recession For Management Of Esotropia With Distance/Near Disparity: A Retrospective Study, Heba Metwally

Journal of Medicine in Scientific Research

Aims This study aimed to compare the efficacy of medial rectus slanting recession and the bilateral medial rectus Faden with or without recession in the management of any type of convergence excess esotropia with low or high accommodative convergence/accommodation ratio. Patients and methods A total of 38 patients with convergence excess esotropia were divided into group A, which underwent bilateral medial rectus recession according to the average angle of near and distance, and group B, which underwent bilateral medial rectus Faden technique with or without recession. All patients who met the inclusion criteria of the study had complete ophthalmic examination …

Bimedial Recti Slanted Recession Versus Bimedial Recti Y-Split Recession For Surgical Management Of Infantile-Onset Esotropia, Heba M. Ali

Journal of Medicine in Scientific Research

Context Bimedial recti Y-split recession is a new intervention for the weakening of the medial recti muscle in patients suffering infantile-onset esotropia. Few studies assessed the efficacy and safety of this procedure compared with other procedures that have been in use. Aims To evaluate bimedial recti slanted recession versus bimedial recti Y-split recession for surgical management of infantile-onset esotropia. Patients and methods This cohort study included patients with infantile esotropia. Patients were divided into two groups according to the procedure performed (bimedial recti Y-split recession or slanted recession). Patients were followed up on the first postoperative day, the first week, …

Torsion Of A Wandering Spleen: A Case Report With Emphasis On Image Findings, Ahmad Abdelhady, Mohammad El-Maghawri

Journal of Medicine in Scientific Research

No abstract provided.

The Effectiveness Of Chest Physiotherapy On Mechanically Ventilated Neonates With Respiratory Distress Syndrome: A Randomized Control Trial, Abeer E. S. Hamed, Rabab Salah El Din Mohamed

Journal of Medicine in Scientific Research

This study aimed to investigate the effect of chest physiotherapy on mechanically ventilated neonates with respiratory distress syndrome. Thirty neonates were concluded in the study where their age ranged from 1 to 28 days. They were divided into two equal groups. Group A was the control group that received medical treatment and mechanical ventilation. Group B or the study group has received the same treatment and the chest physiotherapy program. The physiotherapy session was conducted daily until the child was weaned off the ventilator. The results showed significant differences in vital signs, blood gases, oxygen saturation, respiratory stay, and hospital …

Deep Inspiration And End Exhale Breathhold Evaluation For The Treatment Of Locally Advanced Pancreatic Adenocarcinoma Using The Viewray Mridian Linactm, Tatum Mcglynn

Masters Projects

Introduction

Radiation therapy has been limited in the treatment of locally advanced pancreatic cancer. This is due to the dose tolerance to nearby organs at risk and breathing motion. Advancements in radiation treatment technology have now allowed pancreatic patients to be treated to higher doses in fewer fractions using stereotactic body radiotherapy treatment. With the use of MRI-guided treatments, using the ViewRay MRIdian linac, doses can be escalated using online adaptive treatment planning and real time tracking. However, there has yet to be an optimal breathhold technique investigated that can aid in this process.

Methods

Five patients that had been …

Factors Contributing To Sars-Cov-2 Vaccine Hesitancy Of Hispanic Population In Rio Grande Valley, Athina Bikaki, Michael Machiorlatti, Loren Cliff Clark, Candace A. Robledo, Ioannis A. Kakadiaris

School of Medicine Publications

Hispanic communities have been disproportionately affected by economic disparities. These inequalities have put Hispanics at an increased risk for preventable health conditions. In addition, the CDC reports Hispanics to have 1.5× COVID-19 infection rates and low vaccination rates. This study aims to identify the driving factors for COVID-19 vaccine hesitancy of Hispanic survey participants in the Rio Grande Valley. Our analysis used machine learning methods to identify significant associations between medical, economic, and social factors impacting the uptake and willingness to receive the COVID-19 vaccine. A combination of three classification methods (i.e., logistic regression, decision trees, and support vector machines) …

The Association Between Dietary Inflammatory Index, Dietary Antioxidant Index, And Mental Health In Adolescent Girls: An Analytical Study, Parvin Dehghan, Marzieh Nejati, Amir Almasi-Hashiani, Sevda Saleh-Ghadimi, Rezza Parsi, Hamed Jafari-Vayghan, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd

Faculty Publications

Background Diet is considered as one of the modifiable factors that appears to exert a vital role in psychological status. In this way, we designed this study to examine the association between dietary inflammatory index (DII), dietary antioxidant index (DAI), and mental health in female adolescents. Methods This cross-sectional study included 364 female adolescents selected from high schools in the five regions of Tabriz, Iran. A 3-day food record was used to extract the dietary data and calculate DII/DAI scores. DII and DAI were estimated to assess the odds of depression, anxiety, and stress based on the Depression Anxiety Stress …

Continuum Of Maternal And Newborn Health In Sierra Leone: A 2019 National Survey, Quraish Sserwanja, Mutisya M. Linet, Lilian Nuwabaine, Kassim Kamara, Ronald Mutebi, Milton W. Musaba

School of Nursing & Midwifery, East Africa

Introduction

Globally, Sierra Leone has some of the worst maternal and child health indicators. The situation is worsened by a dearth of evidence about the level of continuum of care, an evidence-based intervention aimed at reducing maternal and perinatal morbidity and mortality. Hence this study aimed to assess the level of and factors associated with continuum of maternal and newborn care in Sierra Leone.

Method

This study analyzed secondary data from the 2019 Sierra Leone Demographic Health Survey. Analysis was restricted to women who had a live birth in the 5 years preceding the survey (n = 7326). Complete …

Use Of The Prepare Tool To Increase Completion Rates Of Advance Care Planning Documentation, Janella Thompson

Student Scholarly Projects

Practice Problem: One in three adults aged 55 and older admitted to the hospital lack advance care planning. Patients without advance care planning may not receive treatment that reflects their personal values, wishes, and preferences

PICOT: The PICOT question that guided this project was in adults 65 years or older (P), how does the implementation of a patient-centered web-based advance planning tool kit (I) compared to the usual practice of addressing advance care planning (C), affect the completion rate of advance care planning documentation (O) within 10 weeks (T).

Evidence: The current evidence has demonstrated that advanced care …

Understanding The Effectiveness Of Diabetes Self-Management Education On Psychological Distress And Self-Care Activity Measures: A Focus On Latinx Community, Anita Khadka

Doctoral Projects

The psychological distress that people with diabetes experience makes them twice likely to have clinical depression. Diabetes self-management education and support is an effective strategy to improve psychological distress and increase self-care activity measures. However, there has been limited knowledge on the impact of formal diabetes self-management education and support DSME/S on psychological distress among minority populations such as Latinx. The primary objective of this study is to explore the impact of diabetes self-management education on psychological distress and self-care activity measures. This study also explores the impact of demographic variables of the Latinx respondents on psychological distress and self-care …

Quantifying The Dosimetric Impact Of Target Margins In The Oligometastatic Setting, Jessica E. Strang

Masters Projects

Introduction

With advancements in cancer treatment therapies, patients are living longer with oligometastatic disease. These patients may have multiple targets and may be treated in a single isocenter to reduce overall treatment time. However, the most considerable risk of treating multiple lesions in a single isocenter is a geometric miss. It can be challenging to perform daily alignment of multiple lesions creating a need to prioritize one lesion alignment over others or abort treatment.

Methods

This study quantified the dosimetric impact of total lung exposure as the planning target volume (PTV) margin incrementally increased for multiple intrathoracic lesions.

The analysis …

Cross-Linked Chitosan/Gelatin Beads Loaded With Chlorella Vulgaris Microalgae/Zinc Oxide Nanoparticles For Absorbing Carcinogenic Bisphenol-A Pollutant From Water, Hazim M Ali, Omar M Ibrahim, Ahmed S M Ali, Mahmoud A Mohamed, Rehab Y Ghareeb, Elsayed E Hafez, Mohamed R El-Aassar

2020-Current year OA Pubs

Water polluted by phenolic compounds is a global threat to health and the environment; accordingly, we prepared a green novel sorbent biological system from a chitosan (CS), gelatin (GT), and

Insights Into Microbiome And Metabolic Signatures Of Children Undergoing Peanut Oral Immunotherapy, Andrea C Blackman, Santosh Thapa, Alamelu Venkatachalam, Thomas D Horvath, Jessica K Runge, Sigmund J Haidacher, Kathleen M Hoch, Anthony M Haag, Ruth Ann Luna, Aikaterini Anagnostou

Faculty, Staff and Students Publications

BACKGROUND: Peanut oral immunotherapy has emerged as a novel, active management approach for peanut-allergic sufferers, but limited data exist currently on the role of the microbiome in successful desensitization.

OBJECTIVE: We examined the oral and gut microbiome in a cohort of 17 children undergoing peanut oral immunotherapy with the aim to identify the microbiome signatures associated with successful desensitization. We also set out to characterize their fecal metabolic profiles after successful therapy.

METHODS: Participants gradually built up their daily dose from 2 mg (starting dose) to 300 mg (maintenance dose) within approximately 40 weeks. We collected a buccal and stool …

Utilization Of A Block Excellence Specialty Team Is B.E.S.T, Lauren E. Pittman

Master's Projects and Capstones

Perioperative registered nurses and anesthesiologists that rely on a process for placing regional anesthesia (R.A.) blocks on the correct side for surgical patients consistently provide high-quality, safe care. Infrequently anesthesiologists place the wrong side peripheral nerve blocks (P.N.B.). Due to the sensitive nature of sentinel events, the frequency of its occurrence at this quality improvement (Q.I.) project site is unavailable. Therefore, a report by Harris et al. (2021) was referenced for the incidence of wrong side blocks (W.S.B.), which were recorded in worldwide, national, and multihospital health care system cohorts as 3.63/10,000, 1.6/10,000, and 1.28/10,000 respectively. The PreOp/PACU nursing staff …

Development Of A Fall Prevention Bundle With Evidence-Based Tools For Hospitalized Adults, Kelly A. Tirone

Master's Projects and Capstones

Problem

One million hospitalized people fall annually in the United States, and up to a third are preventable.

Context

Data from an acute care hospital show one medical-surgical unit reported eight patient falls in 2021, two causing major harm that reached sentinel event criteria.

Interventions

A Clinical Nurse Leader (CNL) leveraged the unique CNL skill set and characteristics of Human-Centered Leadership to engage in horizontal leadership, injury prevention, and team coordination through authentic human connection. The team leveraged documentation for improved fall risk communication. Unavoidable disruptions hindered other planned interventions.

Measures

Outcome measures observe for total fall count and the …

Intervention To Increase Home Preparation For Colonoscopies, Joshua Victor Stone

Master's Projects and Capstones

Abstract

Problem: Inpatient colonoscopies are costly to healthcare systems and inconvenient for eligible patients. The cost for a two-night inpatient bed is currently $4800.00 currently. The department manager led a five-month quality improvement project that was initiated in one 180-bed community medical center in Northern California to increase outpatient options, reduce the census and decrease the admission rate.

Context: Overburdened medical facilities often miss the opportunity to utilize ambulatory procedures due to competing operational priorities. In this setting, the Care Without Delay (CWD) department microsystem addresses barriers that impact operational throughput, efficiency, and unnecessary admissions.

Intervention: A …

Does Screening Of Patients In The Home Health Setting Prevent Sepsis Readmissions?, Heather Michelle Cook

Doctoral Dissertations and Projects

The purpose of this evidence-based project is to reduce 30-day readmission rates of patients diagnosed with septicemia by using a symptom screening tool in the home health setting. Sepsis is a life-threatening and costly healthcare burden. Through this project the home health department staff were educated on the pathology of sepsis, and the use of the adult sepsis screener to identify at risk patients early and manage their symptoms thereby reducing 30-day hospital readmission rates of patients diagnosed with sepsis.

Provider Knowledge And Confidence With Implementing Pediatric Adverse Childhood Experiences (Aces) Screening Tool In An Alaskan Family Practice Clinic, Lisa Marie Wangberg

Doctoral Dissertations and Projects

Adverse childhood experiences (ACEs) have been known to be associated with negative developmental and long-term health sequalae since Felitti and colleagues (1998) presented their groundbreaking research nearly a quarter of a century ago. Pediatric and primary care settings have been relatively slow to implement any type of ACEs screening at regular intervals such as at well-child exams (WCEs). A scholarly project implementation was used to present ACEs education and screening training to pediatric primary care providers in a small, private, rural family health care practice in Alaska. The goal of the project was to determine if providers felt more knowledgeable …

Impact Of Emergency Department Triage Sepsis Screening Algorithm And Treatment Order Sets: An Integrative Review, Danielle Marie Tester

Doctoral Dissertations and Projects

Sepsis is a life-threatening condition that can lead to tissue damage, end-organ damage, and death if left untreated. The Centers for Disease Control and Prevention defines sepsis as a severe response to an infection. Sepsis is prominent health concerns worldwide, as it continues to be a leading cause of mortality despite having access to health care. This has impelled many health care organizations to improve sepsis-related care and sepsis outcomes by formulating core measures to improve patient care. The purpose of this integrative review is to discuss if initiation of an emergency department triage sepsis screening algorithm and treatment order …

Ex Vivo Biomechanical Comparison Of A Novel Compression Screw Fastener And Traditional Ao Cortical Bone Screw For Fixation Of A Simulated Slab Fracture In The Equine Third Carpal Bone, Allison Salinger

Theses and Dissertations

Frontal plane slab fractures account for the majority of third carpal bone (C3) fractures in performance horses. Treatment is stabilization with an AO cortical screw. Complications are fragment splitting, fragment spinning, and irritation of dorsal soft tissue structures. A novel, headless, cannulated screw with interlocking threads (the Headless Compression Screw Fastener, HCSF) has been developed to resist multidirectional forces. Simulated C3 slab fractures were created in nine paired equine carpi. HCSF or AO cortical screws were loaded in shear to failure. Stiffness, maximum load to failure, and yield load was assessed in linear mixed models. No significant difference was detected …

Assessment Of Postural, Locomotor, And Physical Fitness Status In Individuals With Intellectual And Developmental Disabilities, Alana J. Turner

Theses and Dissertations

Introduction: Postural control and locomotion deficits can be observed during the early years of childhood development and throughout life. For those with disabilities, these deficits can advance past the development years and into adolescence and adulthood while affecting the quality of life and daily activity. Finding interactive rehabilitative activities to delay or limit these deficits is essential for people with disabilities to improve their quality of life, inclusion, and overall movement. Adapted physical activity/sports like badminton and virtual reality could promote improvements in postural and locomotor status for young adults with intellectual and developmental disabilities like cerebral palsy (CP), intellectual …

Ex Vivo Biomechanical Evaluation Of A Novel Screw For Tibial Plateau Leveling Osteotomy, William Seth Kettleman

Theses and Dissertations

Twelve pairs of cadaveric pelvic limbs were harvested from skeletally mature dogs. Tibias were randomly assigned pairwise to two study groups: locking buttress screw fixation (LBS) and bone-screw-fastener fixation (BSF). A tibial plateau leveling osteotomy (TPLO) was performed. Each specimen was positioned in a servohydraulic testing machine to simulate physiological orientation and loading at the mid-point of the stance phase at the walk. Cyclic loading was performed for 30,000 cycles at 4Hz with a peak-load of 1000N. The cyclic test was then continued by stepwise increasing the peak-load at a rate of 75N per 500 cycles until failure of the …

A Scoping Review Of Frameworks In Empirical Studies And A Review Of Dissemination Frameworks, Ana A Baumann, Cole Hooley, Emily Kryzer, Alexandra B Morshed, Cassidy A Gutner, Sara Malone, Callie Walsh-Bailey, Meagan Pilar, Brittney Sandler, Rachel G Tabak, Stephanie Mazzucca

2020-Current year OA Pubs

BACKGROUND: The field of dissemination and implementation (D&I) research has grown immensely in recent years. However, the field of dissemination research has not coalesced to the same degree as the field of implementation research. To advance the field of dissemination research, this review aimed to (1) identify the extent to which dissemination frameworks are used in dissemination empirical studies, (2) examine how scholars define dissemination, and (3) identify key constructs from dissemination frameworks.

METHODS: To achieve aims 1 and 2, we conducted a scoping review of dissemination studies published in D&I science journals. The search strategy included manuscripts published from …

Impact Of Interhospital Transfer Vs. Direct Admission On Acute Ischemic Stroke Patients: A Subset Analysis Of The Complete Registry, Ameer E. Hassan, Osama O. Zaidat, Ashish Nanda, Benjamin Atchie, Keith Woodward, Arnd Doerfler, Alejandro Tomasello, Johanna T. Fifi

School of Medicine Publications

Background: Efficacy of thrombectomy treatment in acute ischemic stroke large vessel occlusion (AIS-LVO) patients is time dependent. Direct admission to thrombectomy centers (vs. interhospital transfer) may reduce time to treatment and improve outcomes. In this subset analysis of the COMPLETE registry, we compared outcomes between direct to thrombectomy center (Direct) vs. transfer from another hospital to thrombectomy center (Transfer) in AIS-LVO patients treated with aspiration thrombectomy.

Methods: COMPLETE was a prospective, international registry that enrolled patients from July 2018 to October 2019, with a 90-day follow-up period that was completed in January 2020. Imaging findings and safety events were adjudicated …

Myc Sensitises Cells To Apoptosis By Driving Energetic Demand, Joy Edwards-Hicks, Kevin Cho, Gary J Patti, Et Al

2020-Current year OA Pubs

The MYC oncogene is a potent driver of growth and proliferation but also sensitises cells to apoptosis, which limits its oncogenic potential. MYC induces several biosynthetic programmes and primary cells overexpressing MYC are highly sensitive to glutamine withdrawal suggesting that MYC-induced sensitisation to apoptosis may be due to imbalance of metabolic/energetic supply and demand. Here we show that MYC elevates global transcription and translation, even in the absence of glutamine, revealing metabolic demand without corresponding supply. Glutamine withdrawal from MRC-5 fibroblasts depletes key tricarboxylic acid (TCA) cycle metabolites and, in combination with MYC activation, leads to AMP accumulation and nucleotide …