Pcom Physician Assistant Class Of 2024 White Coat Ceremony, Philadelphia College Of Osteopathic Medicine

White Coat Ceremony

Program of PCOM Philadelphia Campus 2022 Physician Assistant White Coat Ceremony Program for the Class of 2024.

Remarks from PCOM PA Alumnus: Jenny Boyce, MS, PA-C.

Pandas: How To Recognize And Intervene, Trevor Brackney, Blaine Winters

Student Works

This research paper delves into pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS). PANDAS causes rapid psychiatric changes in children ages 3 to puberty. These changes are most often obsessive-compulsive disorder (OCD) and/or tics, however, anxiety, agitation, mood disorder, depression, oppositional defiance disorder, attention-deficit hyperactivity disorder, hallucinations, memory/cognitive deficits, enuresis, and sleep disturbances have also been noted. Present-day estimations of PANDAS cases would likely prove to be understated if awareness of PANDAS increased (Centner, 2021). The purpose of this paper is to disseminate awareness and data of a disease that has gone relatively unnoticed in American medicine since being defined …

Are We Compulsively Chasing Rainbows?, Olivier George, Serge H. Ahmed, Nicholas W. Gilpin

School of Medicine Faculty Publications

No abstract provided.

Addressing Complex Primary Care Needs For An Older Man Recently Released From Incarceration With Multiple Emergency Department Visits., Saffia Bajwa, Ariba Khan, Michael L. Malone

Journal of Geriatric Emergency Medicine

Purpose: Older prisoners being released into the community need to be placed in a system to help them transition from living in prison to living in a free society. They must adapt in order to find housing, community services, medical, dental and psychiatric care. When the complex social needs of these persons are not fully met, the emergency department is used as a safety net.

Methods and Findings: This paper describes a patient who had multiple emergency department visits which was his routine method of seeking medical care.

Health Care Policy Implications: We believe that public health policy requiring …

Experimental Infection Of Brazilian Free-Tailed Bats (Tadarida Brasiliensis) With Two Strains Of Sars-Cov-2, Angela M. Bosco-Lauth, Stephanie M. Porter, Karen A. Fox, Mary E. Wood, Daniel Neubaum, Marissa Quilici

United States Department of Agriculture Wildlife Services: Staff Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is presumed to have originated from wildlife and shares homology with other bat coronaviruses. Determining the susceptibility of North American bat species to SARS-CoV-2 is of utmost importance for making decisions regarding wildlife management, public health, and conservation. In this study, Brazilian free-tailed bats (Tadarida brasiliensis) were experimentally infected with two strains of SARS-CoV-2 (parental WA01 and Delta variant), evaluated for clinical disease, sampled for viral shedding and antibody production, and analyzed for pathology. None of the bats (n = 18) developed clinical disease associated with infection, shed infectious virus, or …

Employment Loss And Food Insecurity - Race And Sex Disparities In The Context Of Covid-19, Jacquelyn V Coats, Sarah Humble, Kimberly J Johnson, Havisha Pedamallu, Bettina F Drake, Elvin Geng, Charles W Goss, Kia L Davis

2020-Current year OA Pubs

INTRODUCTION: Applying an intersectional framework, we examined sex and racial inequality in COVID-19-related employment loss (ie, job furlough, layoff, and reduced pay) and food insecurity (ie, quality and quantity of food eaten, food worry, and receipt of free meals or groceries) among residents in Saint Louis County, Missouri.

METHODS: We used cross-sectional data from adults aged 18 or older (N = 2,146), surveyed by using landlines or cellular phones between August 12, 2020, and October 27, 2020. We calculated survey-weighted prevalence of employment loss and food insecurity for each group (Black female, Black male, White female, White male). Odds ratios …

A Case Series Of Children With Acute Hepatitis And Human Adenovirus Infection, L Helena Gutierrez Sanchez, Henry Shiau, Julia M Baker, Stephanie Saaybi, Markus Buchfellner, William Britt, Veronica Sanchez, Jennifer L Potter, L Amanda Ingram, David Kelly, Xiaoyan Lu, Stephanie Ayers-Millsap, Wesley G Willeford, Negar Rassaei, Julu Bhatnagar, Hannah Bullock, Sarah Reagan-Steiner, Ali Martin, Michael E Rogers, Anna M Banc-Husu, Sanjiv Harpavat, Daniel H Leung, Elizabeth A Moulton, Daryl M Lamson, Kirsten St George, Aron J Hall, Umesh Parashar, Adam Macneil, Jacqueline E Tate, Hannah L Kirking

Faculty, Staff and Students Publications

BACKGROUND: Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 and early 2022, several previously healthy children were identified with acute hepatitis and human adenovirus viremia.

METHODS: We used International Classification of Diseases, 10th Revision, codes to identify all children (<18 years of age) with hepatitis who were admitted to Children’s of Alabama hospital between October 1, 2021, and February 28, 2022; those with acute hepatitis who also tested positive for human adenovirus by whole-blood quantitative polymerase chain reaction (PCR) were included in our case series. Demographic, clinical, laboratory, and treatment data were obtained from medical records. Residual blood specimens were sent for diagnostic confirmation and human adenovirus typing.

RESULTS: A total of 15 children were identified with acute hepatitis - 6 (40%) who had hepatitis with an identified cause and 9 (60%) who had hepatitis without a known cause. Eight (89%) of the patients with hepatitis of unknown cause tested positive for human adenovirus. These 8 patients plus 1 …

Dietary Intake Among Children Attending Childcare Centers: Impact Of The New Cacfp Meal Guidelines, Jayna M Dave, Tzuan A Chen, Maha Almohamad, Sonia Cotto-Moreno

Children’s Nutrition Research Center Staff Publications

Through the Healthy, Hunger-Free Kids Act of 2010, USDA (US Department of Agriculture) made the first major changes in the CACFP (Child and Adult Care Food Program) meal and snack menu patterns. Childcare centers that serve low-income families qualify to participate and receive reimbursement for meals and snacks served. The purpose of this study was to assess what changes in children's dietary behaviors occurred as a result of the new CACFP meal pattern requirements. This study evaluated these changes at childcare centers operating in Houston and San Antonio, Texas, USA, areas enrolled in the CACFP, pre- (Spring 2016) and post-implementation …

Standardizing Perinatal Mental Health Interventions: A Guide For The U.S., Maile Lauren Robles

Master's Projects and Capstones

The term perinatal individual refers to women and other individuals who are pregnant or who have been pregnant within the last 12 months. Every year, in the United States there are 700 pregnancy-related deaths and 10% are due to mental health causes including death by suicide. Mental health conditions including but not limited to anxiety, depression, substance use disorders, and post-traumatic stress disorder affect one in five perinatal individuals throughout the United States. This increases perinatal morbidity, hospitalization costs, and economic burden nationwide.

After 43 days postpartum, mental health conditions are the second leading cause of death. The United States …

Child Health In Darfur, Sudan: Addressing The Effects Of Armed Conflict On Children's Health In Darfur, Judith Natukunda

Master's Projects and Capstones

ABSTRACT

Background: For 19 years, the Darfur region of Sudan has experienced unending civil unrest and war, resulting in more than 2 million deaths and over 4 million displaced persons. The war led to severe food insecurity, clean and safe drinking water shortages, high disease prevalence, destruction of infrastructure, and a broken health care system. Despite the interventions by the global community and various humanitarian agencies, over 2.8 million people are still displaced and living in IDP camps across Darfur. Over 300,000 children are living in neighboring Chad. The armed conflict led to high levels of child malnutrition, a high …

Covid-19 Youth Ambassador Corp, A Community-Based Program To Address Vaccine Hesitancy, Atoosa Azarang

Master's Projects and Capstones

With over one million confirmed deaths from COVID-19, the United States (U.S.) continues to battle the public health crisis arising from the spread of the SARS-CoV-2 virus. The COVID-19 pandemic has had a devastating impact on our economic, social, and health systems. Social distancing efforts and other precautionary measures such as mask-wearing have not sufficiently reduced morbidity and mortality from COVID-19; thus, COVID-19 vaccinations are an important tool for substantially alleviating the effects of the pandemic. Although COVID-19 vaccines are available to all Americans aged six months and older, many individuals are hesitant to receive vaccines. The two most common …

The Impact Of Increased Interdisciplinary Communication On Hospital Admission Rates In The Geriatric Population: An Integrative Review, Molly K. Langston

Doctoral Dissertations and Projects

The medical complexity of geriatric residents puts them at an increased risk of hospital readmissions related to coronary artery disease, myocardial infarction, chronic obstructive pulmonary disease, and diabetes, along with other chronic diseases. Geriatric residents of assisted living, skilled nursing, and memory care facilities should hold a particular interest to stakeholders, as the simple intervention of increasing early communication and correspondence regarding chronic diseases can have a great impact on quality improvement outcomes as well as financial burden of the institution. Additionally, interdisciplinary communication can be individualized to meet the needs of each geriatric resident in order to reduce the …

An Icu-Specific Pressure Injury Risk Assessment Tool To Improve Outcomes, Solange Flore Kamdem

Doctoral Dissertations and Projects

Aim: To use an ICU-specific pressure injury (PI) risk assessment scale to promptly identify the risk for PIs in critically ill patients and promptly implement the appropriate PI prevention interventions to decrease the incidence rate of pressure injuries over 11 weeks.

Background: The risk of developing PIs is 3.8 times higher in the ICU patients than in other patient populations. The state of illness and or treatments increase their odds of developing hospital-acquired pressure injuries (HAPIs). The Braden scale currently in use may not identify the risk early enough to provide preventive interventions. An ICU-specific tool is needed to screen …

The Overlooked Mission-Transitional Care Programs For Veterans In Civilian Settings: An Integrative Review, Cynthia Louise Gonzales

Doctoral Dissertations and Projects

The number of veterans within the United States continues to increase. With the addition of healthcare laws, veterans can seek care within the Veterans Health Administration (VHA) and civilian settings. The collaboration among multiple healthcare providers must ensure veterans are provided safe and efficient care when transitioning from provider to provider. Transitional care programs (TCPs) are effective strategies to ensure that veterans receive safe and efficient healthcare. The VHA employs interventions across their healthcare settings to facilitate optimal care. A variety of TCPs were discovered during the review. Most TCPs were used in VHA settings, which revealed an opportunity to …

Non-Canonical Odor Coding In The Mosquito, Margaret Herre, Olivia V Goldman, Tzu-Chiao Lu, Gabriela Caballero-Vidal, Yanyan Qi, Zachary N Gilbert, Zhongyan Gong, Takeshi Morita, Saher Rahiel, Majid Ghaninia, Rickard Ignell, Benjamin J Matthews, Hongjie Li, Leslie B Vosshall, Meg A Younger

Center on Aging Staff Publications

Aedes aegypti mosquitoes are a persistent human foe, transmitting arboviruses including dengue when they feed on human blood. Mosquitoes are intensely attracted to body odor and carbon dioxide, which they detect using ionotropic chemosensory receptors encoded by three large multi-gene families. Genetic mutations that disrupt the olfactory system have modest effects on human attraction, suggesting redundancy in odor coding. The canonical view is that olfactory sensory neurons each express a single chemosensory receptor that defines its ligand selectivity. We discovered that Ae. aegypti uses a different organizational principle, with many neurons co-expressing multiple chemosensory receptor genes. In vivo electrophysiology demonstrates …

Adiposity, Insulin Resistance, Cardiorespiratory Fitness, And Bone Health In Hispanic Children, Reem S Shawar, Maurice Puyau, Roman Shypailo, Salma Musaad, Nancy F Butte, Fida Bacha

Faculty, Staff and Students Publications

CONTEXT: Childhood obesity disproportionately affects Hispanic youth. The skeletal system appears to be a target organ of the adverse effects of obesity. Yet, the relationship between adiposity and bone health in youth and the modulating factors are not well understood.

OBJECTIVE: This work aims to examine the relationship between adiposity, insulin resistance (IR), cardiorespiratory fitness (CRF), and bone mass in Hispanic youth.

METHODS: A total of 951 Hispanic youth (50% male), aged 4 to 19 years, participated in this cross-sectional design study from the Viva La Familia Study at Children's Nutrition Research Center. Bone mineral content (BMC) and density (BMD), …

Automated Diagnosing Primary Open-Angle Glaucoma From Fundus Image By Simulating Human's Grading With Deep Learning, Mingquan Lin, Bojian Hou, Lei Liu, Mae Gordon, Michael Kass, Fei Wang, Sarah H Van Tassel, Yifan Peng

2020-Current year OA Pubs

Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide. Although deep learning methods have been proposed to diagnose POAG, it remains challenging to develop a robust and explainable algorithm to automatically facilitate the downstream diagnostic tasks. In this study, we present an automated classification algorithm, GlaucomaNet, to identify POAG using variable fundus photographs from different populations and settings. GlaucomaNet consists of two convolutional neural networks to simulate the human grading process: learning the discriminative features and fusing the features for grading. We evaluated GlaucomaNet on two datasets: Ocular Hypertension Treatment Study (OHTS) participants and the Large-scale Attention-based …

Localization Of Epigenetic Markers In Leishmania Chromatin, Jacquelyn R Mcdonald, Bryan C Jensen, Aakash Sur, Iris L K Wong, Stephen M Beverley, Peter J Myler

2020-Current year OA Pubs

Eukaryotes use histone variants and post-translation modifications (PTMs), as well as DNA base modifications, to regulate DNA replication/repair, chromosome condensation, and gene expression. Despite the unusual organization of their protein-coding genes into large polycistronic transcription units (PTUs), trypanosomatid parasites also employ a "histone code" to control these processes, but the details of this epigenetic code are poorly understood. Here, we present the results of experiments designed to elucidate the distribution of histone variants and PTMs over the chromatin landscape of

Metabolomics In Pulmonary Medicine: Extracting The Most From Your Data, Stacey N. Reinke, Romanas Chaleckis, Craig E. Wheelock

Research outputs 2022 to 2026

The metabolome enables unprecedented insight into biochemistry, providing an integrated signature of the genome, transcriptome, proteome and exposome. Measurement requires rigorous protocols combined with specialised data analysis to achieve its promise.

Statistical Analysis Methods Applied To Early Outpatient Covid-19 Treatment Case Series Data, Eleftherios Gkioulekas, Peter A. Mccullough, Vladimir Zelenko

School of Mathematical & Statistical Sciences Faculty Publications

When confronted with a public health emergency, significant innovative treatment protocols can sometimes be discovered by medical doctors at the front lines based on repurposed medications. We propose a statistical framework for analyzing the case series of patients treated with such new protocols, that enables a comparison with our prior knowledge of expected outcomes, in the absence of treatment. The goal of the proposed methodology is not to provide a precise measurement of treatment efficacy, but to establish the existence of treatment efficacy, in order to facilitate the binary decision of whether the treatment protocol should be adopted on an …

Treatment For An Tooth Ankylosis Patient With Corticotomy-Facilitated Orthodontics And Titanium Miniscrew – A Case Report, Po-Yu Yang, Tzu-Hsin Lee

Taiwanese Journal of Orthodontics

This case report is a 31-year-old man with Angle’s class I malocclusion (ANB: 1;wits: -3mm ) , upper and lower anterior crowding, missing lower right second premolar, and ankylosis of lower right first molar (beneath occlusal plane 7 mm). Orthodontic treatment consisted of extraction of #15 (upper right second premolar), and two buccal tipping maxillary third molars ( #18 & #28). A modified corticotomy was performed by the oral surgeon for the ankylosed molar (#46), and a miniscrew was inserted in the upper right first molar #16 region as anchorage. Via this way, we did upright the ankylosis molar and …

Intrusion Of Supraerupted Maxillary Molar Using Posterior Bite Plate And Mini-Screw, Chih-Kai Huang, Chun-Liang Kuo, Yun-I Wang, I-Hua Liu

Taiwanese Journal of Orthodontics

Supraerupted maxillary molars usually result from early loss of the opposing mandible molars. This may induce insufficient intermaxillary space and compromised prosthesis. The best way to deal with supraerupted maxillary molars is no doubt to intrude them. For the minor supraeruption of maxillary molars, simply wearing a posterior bite plate could apply vertical force to intrude them. But the larger supraeruption, combination with temporary anchorage device usage will supply more stable anchorage force to intrude maxillary molars back to the normal position. This article reported three cases, one using only posterior bite plate and the others in combination with mini-screw, …

The Horizontal Plane And Vertical Control During Treatment Of Moderate Angle Class Iii Malocclusion With Anterior Open Bite Cases – Case Report, Huei-Mei Tsai, Ming-Chu Huang, Ming-Jeaun Su

Taiwanese Journal of Orthodontics

To manage moderate mandibular prognathism combined with anterior open bite in adult cases,the dento-alveolar growth has to be guided and carefully utilized during orthodontic treatment, especially when the patients have acceptable profile before treatment and tend to deny the needs of orthognathic surgery. Two cases with similar diagnosis and treatment principle were reported. Extraction of mandibular molars provided spaces for lingual tipping movement of lower incisors, the lower occlusal plane showed a counter-clockwise rotation, the open-bite was accordingly corrected and the molar relationship was also normalized. To be able to command the occlusal plane changes is the key to archive …

Accuracy And Reproducibility Of A Manual 3-Dimensional Superimposition Method To Register Dental Model Images To Cone-Beam Computer Tomography (Cbct) Image – A Preliminary Study, Yu-Shu Liao, Sam Sheng-Pin Hsu, Pei-Ju Lin, Chien-Hsuan Wang, Hsiu-Hsia Lin, Dhruv Singhal, Cheng-Hui Lin, Chiung-Shing Huang, Lun-Jou Lo, Ellen Wen-Ching Ko, Yu-Ray Chen

Taiwanese Journal of Orthodontics

Purpose: The purposes of this study was to evaluate the registration error and its reproducibility for implementation of the laser-scanned dental model images onto the CBCT scan data by using the manual 3D superimposition. Materials and methods: Twelve arches out of 8 consecutive patients were enrolled in this study. Both CBCT and dental impression were taken as orthodontic records and the dental casts were then laser-scanned into dental model images with STL file format. In SimPlant OMS software, we register the dental model images onto CBCT teeth images with manual 3D superimposition technique. Afterwards, validation was performed in 3dMDvultus and …

Intrusion Of Supra-Erupted Maxillary Molars Using Miniscrews– Literature Review, Hsin-Ho Chen, Yu-Kun Chih

Taiwanese Journal of Orthodontics

Overextrusion of maxillary molars usually results from early loss of antagonistic teeth due to caries or periodontitis. Conventional techniques for molar intrusion was used multiple teeth and extraoral devices, that depended highly on patient’s cooperation and usually result in extrusion of other teeth rather than posterior intrusion. This article reviews treatment consideration, force mechanics and side effects about miniscrews for intrusion of upper molars. We also present a clinical case to confirm miniscrew treat supra-erupted upper molars successfully.

Orthodontic Treatment Of Double Impacted Canines, Ting-Shiuan Sung, Han-Jen Hsu

Taiwanese Journal of Orthodontics

This is not a perfect case. I made some mistakes during the treatment. I wish every orthodontics can learn something from the case and prevent the mistakes that I have made. This was a 11 years old girl and her chief complained is anterior teeth crowding. The findings of examination were convex facial profile, protrusive upper and lower lip, Angle Class I malocclusion, upper right and lower left canine impacted. The treatment plane were force eruption of the two impacted canine, and extraction of upper and lower bilateral first premolars for anterior teeth retraction. When the upper right canine was …

Total Arch Distalization To Reduce Bimaxillary Protrusion With Temporary Anchorage Devices, Shu-Chun Tsai, Hau-Hueng Chang, Chen-Ying Wang, Chung-Chen Jane Yao

Taiwanese Journal of Orthodontics

Bimaxillary protrusion is defined as convex profile with protrusive upper and lower lips. Therefore the orthodontic treatment goal is to correct the proclination of upper and lower incisors by retracting the incisors into the space usually resulted from four bicuspid extractions. However, with extraordinary development of temporary anchorage device as skeletal anchorage, non-extraction approach could be a treatment option for patients with mild to moderate bimaxillary protrusion. In this case report, we present the treatment of a 28-year-old female patient with skeletal Class II, high mandibular plane angle, and dental Class I bimaxillary protrusion, which combined with gummy smile and …

Treatment Of Class Iii Malocclusion With Anterior Cross-Bite Using Miniscrew Anchorage – Case Report, Jung-Hsuan Cheng, Yu-Chuan Tseng, Chia-Ni Lin, Hong-Po Chang

Taiwanese Journal of Orthodontics

Adult patients with skeletal Class III malocclusion may have several available treatment options: (1) a combination of orthodontic treatment and orthognathic surgery. (2) camouflaged orthodontic treatment with various extraction selections. In this case report, we use miniscrew anchorage to retract mandibular incisors and control labial tipping of maxillary incisors. Not only improving dental occlusion without extraction of teeth (except for wisdom teeth) but also achieving a balanced profile in only 14 months of treatment time.

Periodontal Outcomes Of Impacted Maxillary Central Incisors In 80 Patients Treated With A Combined Surgical-Orthodontic Approach, Kwok-Hing Ho, Yu-Fang Liao

Taiwanese Journal of Orthodontics

Background: Impaction of maxillary central incisors can result in aesthetic problems. The aim of this retrospective study was to examine the periodontal outcomes of impacted maxillary central incisors after surgical exposure and orthodontic extrusion compared to naturally erupted, contralateral incisors (control). Methods: Patients (N=80, 80 central incisors), who had been treated by a surgical-orthodontic approach, underwent a periodontal examination after 6 to 146 months. Periodontal parameters (crown length, keratinized gingival width, gingival scar, and bone loss) of the orthodontically extruded incisors were scored and compared with those of the naturally erupted contralateral incisors (control) in a masked set-up. Results: The …

The Investigation Of Corrosion Behavior Of Self-Ligating And Conventional Metal Brackets In Soft Drinks, Yin-Chi Hsu, Hoi-Shing Luk, Wen-Ken Tai, Chih-Chen Chou, Heng-Ming Chang, Chia-Tze Kao

Taiwanese Journal of Orthodontics

Introduction: Tea, lemon tea and cola are common beverage in our life. The purpose of the present study is to investigate the corrosion behavior of self-ligating and conventional metal brackets in soft drinks. Materials and Methods: Totally, 198 brackets were used. There are Damon Q (Ormco, USA), P OPA-K (TOMY, Japan) and Tenbrook one (OrthoClass, USA).They were all made of 17-4 PH stainless steel. They were divided into four groups of immersing solutions: artificial saliva, tea, lemon tea, and cola. Brackets were immersed in these solutions at an ovan under 37°C for one day and thirty days. Immersing solutions were …