Medicine and Health Sciences Commons^™

Malignancy Masquerading As Steroid Resistant Hypereosinophilic Syndrome, Sonya Parashar, Aarti Pandya

Posters

Introduction: Hypereosinophilia syndrome (HES) is defined as 1500 eosinophils/mL or above with evidence of end-organ damage due to the eosinophils at least 4 weeks apart. Case description: A 3-year-old male was admitted for newly found anterior mediastinal mass and left pleural effusion. About 6 weeks prior to admission, he was seen in his primary care office for difficulty breathing. Despite the appropriate treatment for his symptoms, the patient continued to have significant respiratory symptoms and a chest x-ray showed a large left pleural effusion. He was immediately transferred to a tertiary care center and a CT chest showed large left …

The Causes Of Preterm Neonatal Deaths In India And Pakistan (Purpose): A Prospective Cohort Study, Sangappa M. Dhaded, Sarah Saleem, Shivaprasad S. Goudar, Shiyam Sunder Tikmani, Kay Hwang, Gowdar Guruprasad, Gayathri H. Aradhya, Varun B. Kusagur, Sana Roujani, Sayyeda Reza

Community Health Sciences

Background: Preterm birth remains the major cause of neonatal death worldwide. South Asia contributes disproportionately to deaths among preterm births worldwide, yet few population-based studies have assessed the underlying causes of deaths. Novel evaluations, including histological and bacteriological assessments of placental and fetal tissues, facilitate more precise determination of the underlying causes of preterm deaths. We sought to assess underlying and contributing causes of preterm neonatal deaths in India and Pakistan.
Methods: The project to understand and research preterm pregnancy outcomes and stillbirths in South Asia (PURPOSe) was a prospective cohort study done in three hospitals in Davangere, India, and …

Daratumumab Plus Lenalidomide, Bortezomib And Dexamethasone In Newly Diagnosed Multiple Myeloma: Analysis Of Vascular Thrombotic Events In The Griffin Study., Douglas W Sborov, Muhamed Baljevic, Brandi Reeves, Jacob Laubach, Yvonne A Efebera, Cesar Rodriguez, Luciano J Costa, Ajai Chari, Rebecca Silbermann, Sarah A Holstein, Larry D Anderson, Jonathan L Kaufman, Nina Shah, Huiling Pei, Sharmila Patel, Annelore Cortoos, J Blake Bartlett, Jessica Vermeulen, Thomas S Lin, Peter M Voorhees, Paul G Richardson

Oncology Articles

Patients with multiple myeloma are at increased risk of vascular thromboembolic events (VTEs). This post hoc analysis evaluated VTEs in the randomised phase 2 GRIFFIN study (ClinicalTrials.gov Identifier: NCT02874742) that investigated lenalidomide/bortezomib/dexamethasone (RVd) ± daratumumab (D). Patients with newly diagnosed multiple myeloma who were eligible for autologous stem cell transplantation (ASCT) received D-RVd/RVd induction, high-dose therapy and ASCT, D-RVd/RVd consolidation and up to 2 years of lenalidomide maintenance therapy ± D. VTE prophylaxis was recommended (at least aspirin, ≥162 mg daily) in accordance with International Myeloma Working Group guidelines. In the safety population (D-RVd, n = 99; RVd, n = …

Lessons From Health, Health Care, And Health Disparities Among Latinx Populations Scientific Panel, In New York City-2021, Andres Valcarcel, Maria-Isabel Roldos, Judith Aponte

Publications and Research

On September 28, 2021 the City University of New York- CUNY’s Institute for Health Equity (CIHE) hosted the online panel: Health, Health Care, and Health Disparities Among Latinx Population as part of a Speaker Series for Hispanic Heritage Month. CIHE is a CUNY-wide institute that coordinates research, teaching, service, and community collaboration to eliminate health inequalities and promote health. The purpose of this perspective is to summarize the key salient discussion points presented by four panelists with expertise in Hispanic and Latinx health of those residing in urban settings; and lessons learned from the Speaker Series.

Pharmacy Newsletter : November 2022, Pharmacy Department

Department of Pharmacy Archives

• Flood Borne Diseases - Current Situation & Its Impact
• Prevention & Management
• Prevent Uncontrolled, Rapid Infusion Rates: Confirm the Infusions are Connected to Pumps Before Opening the Clamp
• Colistin Induced Paresthesia
• Colistin Induced Paresthesia
• TOX TOK: General Treatment Approach To Unknown Poisoning - Coma Cocktail
• Dengue Fever
• Improving the patient safety and quality through Pharmacy Interventions at AKHW&C, Kharadar (Secondary Hospital)
• Food Allergy

Interactions 2022, Thomas J. Long School Of Pharmacy

Interactions

In each issue of Interactions, the School’s annual magazine you will find stories about students, faculty and alumni from each of our disciplines. Learn about the ways our students, faculty and alumni are impacting their communities through health care outreach. Read about their research and how they are contributing to advances in patient care. Meet our Alumni of the Year and get to know our faculty.

Developing Radical Welcome During A Pandemic: Lessons Learned From Moving Community-Researcher-Practitioner Partnerships To Digital Spaces, Mary Mitsdarffer, Sirry Alang, Nyann Biery Ms, Jose Rivera, Abby S. Letcher Md, Autumn Kieber-Emmons Md, Mph, Melanie B. Johnson Mpa, Carol Moeller, Charlene Fulton, Joe Fulton, Yahira Aviles Washington, Michael Briggs, Carolyn Hoffman, Naquon Godfrey, Jose Rivera Jr, Tuoi Dao, Alexandra Bersani Do, Melissa Snyder, Regina Qualls, Veronica Gonzalez Mba, Hasshan Batts

Department of Family Medicine

No abstract provided.

精神病及癌症照顧者的社會支持及需要研究報告, Chak Kwan, Dickon Chan, Meng Soi, Florence Fong, Mun Yu, Vera Tang, Hiu Tung, Angel Chan, Sheung Wan, Wanda Wong, Mei Ling Lee

APIAS Research Report 研究報告

本研究旨在探討非正式照顧者在照顧60歲或以上受精神病或癌症困擾的家庭成員時遇到的困難、長時間照顧工作帶來的問題和他們的非正式社會支持。同時亦針對他們的需要提出相關建議。受精神問題及癌症困擾的年長患者數字持續上升，這兩類患者的非正式照顧者(下文統稱為照顧者)多面對因患者的情緒起伏和病情轉變化而帶來的巨大壓力。為深入了解他們的現況和為制定相關政策及服務提供參考，研究團隊以半結構性訪談的方法搜集了15位精神病及癌症患者的照顧者和17位服務提供者的意見。

研究結果發現，精神病患者照顧者常遇到的困難包括：缺乏私人空間、經濟壓力大、對相關疾病資訊不了解和因社會的負面標籤不願向外界求助。同時，他們因要長時間照顧患者，人際關係、身體狀況和就業狀況均受到負面影響。對於照顧癌症家屬的照顧者，他們多不了解現有的支援服務，而且需要面對沉重的經濟壓力。由於需要長時間照顧患者，照顧者的日常生活和心理狀況皆受到影響，他們與患者的關係轉差。這兩類照顧者的非正式社會支援網絡主要為家人、朋友及教會會友。

針對照顧者的需要，研究團隊提出了五個建議。一、加強公眾教育以去除社會對精神病患者的負面標籤，減低患者家人及照顧者對尋求外界協助的顧慮。二、增加暫託服務的資源和人手以縮短輪候時間，並推行以地區為本的照顧者「社區保姆」計劃，提供空間予照顧者暫時離開患者，以處理突發或私人事務。三、設立地區性照顧者服務中心，提供輔導服務，推行照顧者技巧培訓、經濟諮詢、喘息活動和「社區保姆」計劃，令到照顧者可以在同一個服務單位獲得所需的服務。四、政府可透過線上資源整合平台為照顧者提供相關照顧資訊，讓照顧者及其家庭更易知悉社會支援服務。對於年長的照顧者，建議政府可以在他們常出現或較容易接觸到的地方擺設攤位街站，派發相關小冊子。五、增加照顧者的經濟支援，提供「喘息及活動津貼」，並且將「照顧元素」融入經濟援助項目，使到綜援申請人和長者生活津貼領取人可獲得一定比率的照顧者津貼金額。

Programmatic Impacts Of Utilizing Various Staffing Options For Covid-19 Contact Tracers: Recommendations And Lessons Learned, Michael Wiese, Alison Oberne, Laura Rusnak, Patrick Rodriguez, Matawal Makut

Florida Public Health Review

Background: The rapidly expanding COVID-19 pandemic created an immediate demand for the Department of Health in Hillsborough County (DOH-Hillsborough) Epidemiology Program to supplement its contact tracing workforce; and, because of the long duration of the response, a sustained workforce was needed. The DOH-Hillsborough Epidemiology Program’s COVID-19 response, broadly referred to as “contact tracing”, included case investigations, outbreaks, and identification and notifications to exposed individuals. To meet contact tracing staffing needs, several staffing options were utilized, including Core Epidemiology Staff, Reassigned DOH-Hillsborough staff (Reassigned Staff), Contracted staffing agency hires (Contract Staff), State of Florida hires (State Level Hires), County hires (DOH-Hillsborough …

Disparities In Covid-19 Case Counts And Incidence In Florida By Race And Ethnicity At The County And State Level, Elizabeth Weaver

Florida Public Health Review

Background: In 2020, as COVID-19 spread across the United States, reports of disparities in COVID-19 incidence and mortality by race and ethnicity soon followed. This study assessed COVID-19 case counts and incidence by race and ethnicity at county and state levels focusing on Florida.

Methods: Counts of COVID-19 were collected from June through December 2020. Chi square analyses assessed disparities in case distribution and linear regressions assessed disparities in incidence and potential interaction between predictors.

Results: Race and ethnicity were significant predictors of COVID-19 incidence. Mean incidence was 4.9, 6.6, and 14.3 per 1,000 people among White, Black, and Other …

Implementation Of An Electronic, Secure, Web-Based Application To Support Routine Hand Hygiene Observation With Immediate Direct Feedback And Anonymized Benchmarking, Simon Simonet, Jonas Marschall, Rolf Kuhn, Matthias Schlegel, Christian R Kahlert

2020-Current year OA Pubs

A secure web-based electronic tool was developed and implemented to record adherence to hand hygiene during routine care and to provide direct feedback including anonymized benchmarking. It was found suitable for documenting hand hygiene improvements in a local campaign and following rollout to other institutions in 2013, the tool is currently used in >100 hospitals in Switzerland and will play a major part in upcoming national hand hygiene campaigns.

Inclusive Leadership To Guide Nursing’S Response To Improving Health Equity, Jacqueline Nikpour, Ronald L. Hickman, Dora L. Clayton-Jones, Rosa M. Gonzalez-Guarda, Marion E. Broome

College of Nursing Faculty Research and Publications

The purpose of this manuscript is to examine traditional models of leadership in nursing, and to provide a roadmap and specific recommendations for nurses at all levels to lead our profession through the next decade in achieving health equity. We examine current leadership frameworks in nursing and discuss ways to contemporize these frameworks to more explicitly center the expertise of clinicians and communities from historically marginalized backgrounds. Next, we examine the racial, gender, and able-bodied biases that impact nurses, and call upon nurses to examine and dismantle these biases. We discuss the roles of health systems and academic organizations in …

Integration Of A Simulation Curriculum Across Semesters In An Acute Care Pediatric Nurse Practitioner Program, Katie L. Mcdermott, Jennifer K. Pfister, Jill C. Kuester, Leslie Talbert, Christine A. Schindler

College of Nursing Faculty Research and Publications

Introduction

Simulation is a common strategy for health care education. Research regarding simulation for nurse practitioner education is sparse. This paper describes the integration of a nine simulation session curriculum into a nurse practitioner program, including motivating factors, process description, and lessons learned.

Results

Students report high satisfaction and improved perception of confidence and competence of knowledge, skills, and performance.

Discussion

Integrated learning experiences and outcomes that span an educational program are needed in the transition to competency-based education. This description serves as a guide for other programs seeking to incorporate simulation-based education.

Running As A Way Fat Women Re-Story Their Bodies And Construct A Runner Identity In A North American Sociocultural Context, Jennifer M. Ohlendorf, Lisa Anders

College of Nursing Faculty Research and Publications

Aim

This research sought to identify the process by which women who identify as fat or as not having a typical athletic body construct an athletic identity and persist in their running and other athletic endeavors despite body size-related barriers.

Methods

From an online recruitment effort, 19 North American women runners in larger bodies completed interviews in which they told the story of how they had become runners. A narrative analysis with a feminist, constructivist approach was conducted to identify story types.

Results

Four narrative types were identified: reclaiming the body, reclaiming health, space-making, and future-imagining. Through finding a size- …

Atrial Fibrillation With Controlled Ventricular Rate And New-Onset Heart Failure: Atypical Presentation, Worse Prognosis, Vinay Mehta, Alexander Albers, Maharaj Singh, Timothy E. Paterick

College of Nursing Faculty Research and Publications

Background: There is deficient literature comparing patients with atrial fibrillation (AF) who present with rapid ventricular rate (RVR) versus controlled ventricular rate (CVR) associated with new-onset heart failure.

Purpose: This study aimed to evaluate patients with new-onset cardiomyopathy (CM) and a concomitant or preceding history of AF and compare patients with CVR (≤100 bpm) to those with RVR (>100 bpm).

Methods: Patients with newly diagnosed CM, defined as a left ventricular ejection fraction ≤40%, were identified from our healthcare database and divided into two groups: those with a ventricular rate ≤100 bpm (CVR-CM, n=79) and those with a ventricular …

Clinical Characteristics Of Children With Cerebral Injury Preceding Treatment Of Diabetic Ketoacidosis, Nicole S Glaser, Kimberly S Quayle, Et Al.

2020-Current year OA Pubs

Previous studies have identified more severe acidosis and higher blood urea nitrogen (BUN) as risk factors for cerebral injury during treatment of diabetic ketoacidosis (DKA) in children; however, cerebral injury also can occur before DKA treatment. We found that lower pH and higher BUN levels also were associated with cerebral injury at presentation.

Dose-Dependent Seizure Control With Mek Inhibitor Therapy For Progressive Glioma In A Child With Neurofibromatosis Type 1, Evan Cantor, Ashley Meyer, Stephanie M Morris, Judith L Z Weisenberg, Nicole M Brossier

2020-Current year OA Pubs

BACKGROUND: Low-grade gliomas (LGGs) occurring in children can result in many different neurologic complications, including seizures. MEK inhibitors are increasingly being used to treat LGG, but their effect on associated neurologic symptoms has not been established.

RESULTS: Here, we report a patient with neurofibromatosis type 1 (NF1), medically refractory epilepsy (MRE), and an extensive optic pathway glioma (OPG) who developed dose-dependent seizure control while being treated with selumetinib. Seizure frequency rebounded after dose reduction for cardiac toxicity, then improved, and finally ceased after restarting full dosing, allowing confidence in the cause of improvement.

CONCLUSION: Selumetinib may have promise in epilepsy …

Loneliness, Social Isolation, And Social Support In Older Adults With Active Cancer During The Covid-19 Pandemic, Katherine Clifton, Feng Gao, Joann Jabbari, Mary Van Aman, Patricia Dulle, Janice Hanson, Tanya M Wildes

2020-Current year OA Pubs

INTRODUCTION: The COVID-19 pandemic has had a considerable impact on mental health. The social distancing and stay-at-home orders have likely also impacted loneliness, social isolation, and social support. Older adults, particularly those with comorbidities such as cancer, have a greater potential to be impacted. Here we assessed loneliness, social isolation, and social support in older adults undergoing active cancer treatment during the pandemic.

MATERIALS AND METHODS: A mixed methods study in which quantitative data and qualitative response items were collected in parallel was conducted in 100 older adults with cancer. Participants completed a survey by telephone with a series of …

Importance Of First Pass Reperfusion In Endovascular Stroke Care - Insights From Thrombectomy And Aneurysm Registry (Star), Ilko L Maier, Joshua Osbun, Et Al.

2020-Current year OA Pubs

BACKGROUND: Mechanical thrombectomy has become the first-line treatment strategy for patients with large-vessel occlusion strokes. Often >1 thrombectomy maneuver is necessary to achieve reperfusion. A first-pass (FP) effect with improved functional outcomes after mechanical thrombectomy has been described. Aim of the present study is to investigate the FP effect in a large, international, multicenter stroke database.

METHODS: Patients who underwent mechanical thrombectomy for large-vessel occlusion stroke in the anterior cerebral circulation between January 2014 and January 2021 and achieved complete reperfusion were identified from the STAR (Stroke Thrombectomy and Aneurysm Registry). We compared functional outcomes of patients with FP (defined …

Predictive Self-Organizing Neural Networks For In-Home Detection Of Mild Cognitive Impairment, Seng Khoon Teh, Iris Rawtaer, Ah-Hwee Tan

Research Collection School Of Computing and Information Systems

In-home sensing of daily living patterns from older adults coupled with machine learning is a promisingapproach to detect Mild Cognitive Impairment (MCI), a potentially reversible condition with early detectionand appropriate intervention. However, the number of subjects involved in such real-world studies istypically limited, posing the so-called small data problem to most predictive models which rely on a sizablenumber of labeled data. In this work, a predictive self-organizing neural network known as fuzzy AdaptiveResonance Associate Map (fuzzy ARAM) is proposed to detect MCI using in-home sensor data collected from aunique Singapore cross-sectional study. Specifically, mean and standard deviation of nine in-home …

The Effect Of Experiential Avoidance And Committed Action On The Relationship Between Anxiety And Quality Of Life In Chronically Ill And Healthy Students, Rufaida Mohammed N Alkhanji

Theses

Chronic illness and anxiety are two factors that have been shown to negatively impact quality of life. In order to better understand the impact of chronic illness on quality of life, researchers have been interested in studying the effects of experiential avoidance and committed action. This thesis aims to examine the roles of experiential avoidance and committed action as potential mediators in the relationship between anxiety and quality of life. It also aims to compare the occurrence of the studied relationships in students with and without chronic illness. 547 participants from two Arab universities completed self-report measures assessing their levels …

The Potent And Selective Histamine H3 Receptor Antagonist E169 Alleviates Cognitive Deficits And Mitigates Disturbed Pi3k/Akt/Gsk-3Β Signaling Pathway In Mk801-Induced Amnesia In Mice, Sabna Tagelsir Hassan Abdalla

Theses

The role of Histamine H3 Receptors (H3Rs) in memory and the prospective of H3R antagonists in pharmacological control of neurodegenerative disorders, e.g., Alzheimer’s Disease (AD) is well-accepted. Therefore, the procognitive effects of acute systemic administration of H3R antagonist E169 (2.5-10 mg/kg, i.p.) on MK801- induced amnesia using the Novel Object Recognition Test (NORT) paradigm in C57BL/6J mice were evaluated. E169 (5 mg) provided a significant memory-improving effect on MK801-induced short- and long-term memory impairments in NORT. The E169 (5 mg) provided effects were comparable to those observed with the Phosphatidyl Inositol 3-Kinase (PI3K) inhibitor LY294002 and were abrogated with the …

Outpatient Surgery For Rib Fracture Fixation: A Report Of Three Cases., Daniel T Degenova, Nolan P Schmitz, Jia Bao Lin, Travis J Jones, Benjamin C Taylor

Surgery Articles

Rib fractures are common injuries observed in trauma patients that will often heal without operative intervention. However, patients can infrequently have continued pain. Operative fixation of these symptomatic rib fractures has traditionally led to the patient requiring hospital admission for observation and pain control. The purpose of this study was to review three cases of outpatient rib fracture, open reduction and internal fixation (ORIF) surgery. Three patients with symptomatic rib fractures treated with ORIF at a single urban level one trauma center underwent outpatient same-day surgery. Pertinent demographic, clinical, radiographic, and surgical data were collected. All patients had decreased preoperative …

Modification Of The Tumor Microenvironment Enhances Anti-Pd-1 Immunotherapy In Metastatic Melanoma, Guilan Shi, Megan Scott, Cathryn G. Mangiamele, Richard Heller

Bioelectrics Publications

Resistance to checkpoint-blockade treatments is a challenge in the clinic. Both primary and acquired resistance have become major obstacles, greatly limiting the long-lasting effects and wide application of blockade therapy. Many patients with metastatic melanoma eventually require further therapy. The absence of T-cell infiltration to the tumor site is a well-accepted contributor limiting immune checkpoint inhibitor efficacy. In this study, we combined intratumoral injection of plasmid IL-12 with electrotransfer and anti-PD-1 in metastatic B16F10 melanoma tumor model to increase tumor-infiltrating lymphocytes and improve therapeutic efficacy. We showed that effective anti-tumor responses required a subset of tumor-infiltrating CD8⁺ and CD4 …

An Evaluation Of Peer-Rated Surgical Skill And Its Relationship With Detrusor Muscle Sampling In Transurethral Resection Of Bladder Tumor, Minh N Pham, Oliver S Ko, Reiping Huang, Amanda X Vo, Kyle P Tsai, Jeremy D Lai, Matthew T Hudnall, Joshua A Halpern, Joshua J Meeks, Jonas Benson, Ricardo Soares, Ronald Kim, Karl Y Bilimoria, Jonah J Stulberg, Gregory B Auffenberg

Faculty, Staff and Student Publications

OBJECTIVE: To assess the reliability of peer-review of TURBT videos as a means to evaluate surgeon skill and its relationship to detrusor sampling.

METHODS: Urologists from an academic health system submitted TURBT videos in 2019. Ten blinded peers evaluated each surgeon's performance using a 10-item scoring instrument to quantify surgeon skill. Normalized composite skill scores for each surgeon were calculated using peer ratings. For surgeons submitting videos, we retrospectively reviewed all TURBT pathology results (2018-2019) to assess surgeon-specific detrusor sampling. A hierarchical logistic regression model was fit to evaluate the association between skill and detrusor sampling, adjusting for patient and …

Nocturnal Dipping And Kidney Function Decline: Findings From The Ckd In Children Study, Christine Y Bakhoum, Manali Phadke, Yanhong Deng, Joshua A Samuels, Pranav S Garimella, Susan L Furth, F Perry Wilson, Joachim H Ix

Faculty, Staff and Student Publications

INTRODUCTION: Normally, blood pressure (BP) declines by at least 10% from daytime to nighttime. In adults, blunted nocturnal dipping has been associated with more rapid decline in kidney function. Nondipping is prevalent in children with chronic kidney disease (CKD). We sought to determine whether nondipping is associated with proteinuria and progression to kidney failure in children with CKD.

METHODS: In the prospective CKD in children (CKiD) cohort, Cox proportional hazards models were used to evaluate the relationship between baseline nondipping and progression to kidney failure. Linear mixed effects models were used to evaluate the relationship between nondipping and changes in …

All The Brain's A Stage For Serotonin: The Forgotten Story Of Serotonin Diffusion Across Cell Membranes, Paul W. Andrews, Catherine Bosyj, Luke Brenton, Laura Green, Paul J. Gasser, Christopher A. Lowry, Virginia M. Pickel

Biomedical Sciences Faculty Research and Publications

In the conventional model of serotonin neurotransmission, serotonin released by neurons in the midbrain raphe nuclei exerts its actions on forebrain neurons by interacting with a large family of post-synaptic receptors. The actions of serotonin are terminated by active transport of serotonin back into the releasing neuron, which is mediated by the serotonin reuptake transporter (SERT). Because SERT is expressed pre-synaptically and is widely thought to be the only serotonin transporter in the forebrain, the conventional model does not include serotonin transport into post-synaptic neurons. However, a large body of evidence accumulating since the 1970s has shown that serotonin, despite …

Anti-Müllerian Hormone Concentration Is Associated With Central Adiposity And Reproductive Hormones In Expectant Fathers, Narelle C. Hadlow, Suzanne J. Brown, Ee Mun Lim, David Prentice, Simone Pettigrew, Sophie L. Cronin, Susan L. Prescott, Desiree Silva, Bu B. Yeap

Research outputs 2022 to 2026

Objective:

The role of the anti-Müllerian hormone (AMH) as an indicator of physical and reproductive health in men is unclear. We assessed the relationships between AMH and follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and metabolic parameters, in a cohort of expectant fathers.

Design:

ORIGINS Project prospective cohort study. Setting: Community-dwelling men.

Participants:

Partners of pregnant women attending antenatal appointments.

Main Outcome Measures:

Serum AMH, FSH, LH, testosterone, and metabolic parameters. Results: In 485 expectant fathers, median age 33 years, median AMH was 40 pmol/L (quartiles 29, 56). AMH was inversely correlated with FSH, age, and body mass index (BMI) …

Neurodevelopment And Recovery From Wasting, Harriet M. Babikako, Celine Bourdon, Emmie Mbale, Peace Aber, Annet Birabwa, Josephine Chimoyo, Wieger Voskuijl, Zaubina Kazi, John Mukisa, Ali Faisal Saleem

Department of Paediatrics and Child Health

Background and objectives: Acute illness with malnutrition is a common indication for hospitalization among children in low- and middle-income countries. We investigated the association between wasting recovery trajectories and neurodevelopmental outcomes in young children 6 months after hospitalization for an acute illness.
Methods: Children aged 2 to 23 months were enrolled in a prospective observational cohort of the Childhood Acute Illness & Nutrition Network, in Uganda, Malawi, and Pakistan between January 2017 and January 2019. We grouped children on the basis of their wasting recovery trajectories using change in mid-upper arm circumference for age z-score. Neurodevelopment was assessed with the …

Covid-19, Nutrition, And Gender: An Evidence-Informed Approach To Gender-Responsive Policies And Programs, Anna Kalbarczyk, Noora-Lisa Aberman, Bregje S M Van Asperen, Rosemary Morgan, Zulfiqar Ahmed Bhutta, Bianca Carducci, Rebecca Heidkamp, Saskia Osendarp, Neha Kumar, Anna Lartey

Department of Paediatrics and Child Health

In addition to the direct health impacts of COVID-19, government and household mitigation measures have triggered negative indirect economic, educational, and food and health system impacts, hitting low-and middle-income countries the hardest and disproportionately affecting women and girls. We conducted a gender focused analysis on five critical and interwoven crises that have emerged because of the COVID-19 crisis and exacerbated malnutrition and food insecurity. These include restricted mobility and isolation; reduced income; food insecurity; reduced access to essential health and nutrition services; and school closures. Our approach included a theoretical gender analysis, targeted review of the literature, and a visual …