Medicine and Health Sciences Commons^™

Necrosis Is An Independent Predictor Of Disease-Free And Overall Survival In Pancreatic Well-Differentiated Neuroendocrine Tumours (Nets): A Proposal To Include It In Grading Systems, Talia L. Fuchs, Angela Chou, Mahsa Ahadi, Amy Sheen, Loretta Sioson, Anubhav Mittal, Jaswinder Samra, Anthony J. Gill

Medical Papers and Journal Articles

Pancreatic neuroendocrine tumours (NETs) are currently graded using the World Health Organization (WHO) 2019 system, which is based solely on mitotic count and Ki-67 proliferative index. Although necrosis is a well-recognised adverse prognostic feature that is included in the grading systems of NETs of certain types such as pulmonary carcinoid and medullary thyroid carcinoma, there is currently insufficient evidence to support its inclusion in the grading of pancreatic NETs. Therefore, we sought to investigate the prognostic significance of tumour necrosis in our cohort of resected pancreatic NETs, with a view to providing evidence to support its incorporation into the WHO …

Defining The Rate Of Nutritional And Metabolic Derangements After Pancreatic Resection, K L. Percy, Y X. Ooi, C B. Nahm, F Simpson, G Hickey, S Sahni, D Chesher, M Itchins, N Pavlakis, V H. Tsang, R Clifton-Bligh, A J. Gill, J S. Samra, A Mittal

Medical Papers and Journal Articles

Background and aims: Pancreatic resection is associated with pancreatic exocrine insufficiency (PEI) leading to nutritional consequences. The Pancreatic Nutrition Clinic was established to diagnose and manage PEI through standardised nutritional assessment. In this prospective observational study, we aimed to define the rate of PEI, diabetes mellitus and nutritional abnormalities in patients who underwent pancreatic resection.

Methods: All Pancreatic Nutrition Clinic patients were included for analysis. Clinical data were prospectively obtained at initial assessment. Biochemical data included micronutrient levels, faecal elastase-1 and haemoglobin A1c. Bone mineral density and nutritional assessment were undertaken.

Results: Ninety-eight patients were included. Fifty-nine per cent (58/98) …

Gastric Bezoars And Glp-1ra Medications [Data Set], Ritesh Patel, Reginald Lord, Tamara C. Preda

Medical Papers and Journal Articles

This dataset relates to journal article: Gastroparesis with bezoar formation in patients treated with glucagon-like peptide-1 receptor agonists: Potential relevance for gastric, especially bariatric, surgery.

Quality Improvement Initiatives In The Care And Prevention Of Fragility Fractures In The Asia Pacific Region, Paul J. Mitchell, Seng Bin Ang, Leilani Basa Mercado-Asis, Reynaldo Rey-Matias, Wen-Shiang Chen, Leon Flicker, Edward Leung, David Choon, Sankara Kumar Chandrasekaran, Jacqueline Clare Therese Close, Hannah Seymour, Cyrus Cooper, Philippe Halbout, Robert Daniel Blank, Yanling Zhao, Jae-Young Lim, Irewin Tabu, Maoyi Tian, Aasis Unnanuntana, Ronald Man Yeung Wong, Noriaki Yamamoto, Ding-Cheng Chan, Joon Kiong Lee, On Behalf Of The Asia Pacific Fragility Fracture Alliance

Medical Papers and Journal Articles

Summary: This narrative review summarises ongoing challenges and progress in the care and prevention of fragility fractures across the Asia Pacific region since mid-2019. The approaches taken could inform development of national bone health improvement Road Maps to be implemented at scale during the United Nations ‘Decade of Healthy Ageing’.

Purpose: This narrative review summarises recent studies that characterise the burden of fragility fractures, current care gaps and quality improvement initiatives intended to improve the care and prevention of fragility fractures across the Asia Pacific region.

Methods: The review focuses on published studies, reports and quality improvement …

The Global Burden Of Fragility Fractures – What Are The Differences, And Where Are The Gaps, Paul J. Mitchell, Ding-Cheng (Derrick) Chan, Joon-Kiong Lee, Irewin Tabu, Bernardino B. Alpuerto

Medical Papers and Journal Articles

The current burden of fragility fractures is enormous, and it is set to increase rapidly in the coming decades as humankind enters a new demographic era. The purpose of this review is to consider, in different settings:

• The human and economic toll of fragility fractures.

• Risk factors for fragility fractures.

• Current acute management of fragility fractures.

• Current care gaps in both secondary and primary fracture prevention.

A summary of global, regional, and national initiatives to improve the quality of care is provided, in addition to proposals for the research agenda. Systematic approaches to improve the acute …

Foot Pain Is Common, But Frequently Improves 1 Year After Total Knee Arthroplasty, David Carmody, Geffrey Keighley, Lucy Salmon, Ka Martina, Leo Pinczewski, Matthew Lyons, Benjamin Gooden, Phil Huang, Michael O'Sullivan, Justin Roe

Medical Papers and Journal Articles

Background: Osteoarthritis frequently affects multiple joints through the lower limbs. This study sought to examine the incidence of foot pain in subjects undergoing total knee arthroplasty (TKA) and determine if foot symptoms improved following surgery.

Methods: Six hundred ten subjects undergoing TKA completed patient-reported outcome measures preoperatively, and at 6 and/or 12 months after surgery including the incidence and severity of foot or ankle pain, Knee Injury and Osteoarthritis Outcome Scores (KOOS) Joint Replacement, Oxford Knee Scores (OKS), EQ5D, and satisfaction.

Results: Foot or ankle pain was reported in 45% before, 32% at 6 months, and 36% at 12 months …

Nurse Staffing And Adverse Events In Residential Aged Care: Retrospective Multi-Site Analysis, Dorika Nhongo, Annie Holt, Tracy Flenady, Amanda Rebar, Kasia Bail

Medical Papers and Journal Articles

Background: People living in residential aged care homes are entitled to a safe environment 24 hours a day, 7 days a week. Unfortunately, past evidence tells us this is not always the case and that our most vulnerable population experience high rates of adverse events.

Aim: To determine whether after-hours shifts are associated with number of adverse events, independent of registered nurse staffing levels and residential aged care home size.

Methods: Retrospective cohort design with multilevel modelling. Adverse events, registered nurse staffing and facility size were collected via routine reporting from ten homes (1020 beds) in one Australian state for …

Repeat Anterior Cruciate Ligament Injury And Return To Sport In Australian Soccer Players After Anterior Cruciate Ligament Reconstruction With Hamstring Tendon Autograft, Jonathan R. Manara, Lucy J. Salmon, Faisal M. Kilani, Gerardo Zelaya De Camino, Claire Monk, Keran Sundaraj, Leo A. Pinczewski, Justin P. Roe

Medical Papers and Journal Articles

Background: Soccer is the most commonly played team sport in the world and a high-risk sport for anterior cruciate ligament (ACL) injury and subsequent ACL reconstruction (ACLR).

Purpose: To assess the rate of further ACL injury in patients who have undergone ACLR with hamstring tendon autograft after soccer injuries in Australia and to determine factors associated with repeat ACL injury and return to soccer.

Study Design: Case-control study; Level of evidence, 3.

Methods: From a prospectively collected database, a series of 1000 consecutive ACLRs using hamstring autografts performed in soccer players were identified. Patients were surveyed at a minimum 5 …

Health Risks From Indoor Gas Appliances, Ben Ewald, George Crisp, Marion G. Carey

Medical Papers and Journal Articles

Background

Cooking and heating with gas is common in Australian homes and is a risk factor for several important health problems; however, there is little awareness of these risks among doctors or the public. Gas stove use is estimated to cause 12% of childhood asthma in Australia.

Objective

The aim of this article is to help general practitioners identify when gas combustion products such as nitrogen dioxide might be contributing to asthma in children and adults and to alert them to the risks of carbon monoxide (CO) poisoning, which can be hard to diagnose.

Discussion

There are excellent alternatives to …

“It’S About Our Bodies… We Have The Right To Know This Stuff”: A Qualitative Focus Group Study On Australian Women’S Perspectives On Breast Density, Brooke Nickel, Hankiz Dolan, Stacy Carter, Nehmat Houssami, Meagan E. Brennan, Jolyn Hersch, Angela Verde, Lisa Vaccaro, Kirsten Mccaffery

Medical Papers and Journal Articles

Objective

This study aimed to explore Australian women’s current knowledge, perspectives and attitudes about breast density (BD); and information needs to inform effective evidence-based communication strategies.

Methods

Fourteen online focus group sessions with a total of 78 women in New South Wales and Queensland, Australia aged 40–74 years without a personal diagnosis of breast cancer were conducted. Audio-recorded data was transcribed and analysed thematically.

Results

Women had a very limited knowledge of BD. Overall, women expressed a preference for more frequent mammograms and/or supplemental screening should they be told they had dense breasts, despite being presented with information on potential …

The Moderating Effect Of Solar Radiation On The Association Between Human Mobility And Covid-19 Infection In Europe, Wenyu Zhao, Yongjian Zhu, Jingui Xie, Zhichao Zheng, Haidong Luo, Oon Cheong Ooi

Research Collection Lee Kong Chian School Of Business

The novel coronavirus disease 2019 (COVID-19) has caused a global pandemic. Some studies have suggested a negative association between sunlight intensity and COVID-19 infection, alluding to the belief that it might be safe to go out on sunny days. This paper examined whether solar radiation mitigated the association between human mobility and COVID-19 infection in Europe using a dynamic panel data model to investigate the effect of human mobility, solar radiation, and their interaction on COVID-19 infection. The results revealed that outgoing mobility was positively correlated and solar radiation was negatively correlated with COVID-19 infection at lag levels of 1, …

Delirium In Hospitalised Adults With Acute Burns – A Systematic Review, Guy H.M Stanley, Angus R.J Barber, Aoife M. O'Brien, Cheryl Hamill, Glenn Boardman, Cody C. Frear, Dale W. Edgar, Hannah Seymour, Fiona M. Wood

IHR Papers and Journal Articles

Introduction: Delirium is a potentially modifiable, acutely altered mental state, commonly characterised as a hospital-acquired complication. Studies of adult inpatients with acute burns with and without delirium identify causative risks related to the injury or treatment and outcomes related to the patient and healthcare system. We compare patients with and without delirium, providing a high-level quantitative synthesis of delirium risks and outcomes to inform guidelines and future research.

Methods: A systematic review, meta-analysis and GRADE evaluation of risks and outcomes associated with delirium in adults with acute burns was conducted using PRISMA guidelines and PROSPERO protocol CRD42021283055. The Newcastle-Ottawa Scale …

A Differential Response To Antihypertensive Therapy In African Men And Women: Insights From The Creole Trial, Dike B. Ojji, Gabriel L. Shedul, Mahmoud Sani, Okechukwu S. Ogah, Anastase Dzudie, Felix Barasa, Charles Mondo, Prossie M. Ingabire, Erika S.W. Jones, Brian Rayner, Damasceno Albertino, Elijah Ogola, Wynand Smythe, Nicky Hickman, Veronica Francis, Pandie Shahiemah, Grace Shedul, Akinyemi Aje, Karen Sliwa, Simon Stewart, For The Creole Investigators

IHR Papers and Journal Articles

Background: We sought to address the paucity of data to support the evidence-based management of hypertension to achieve optimal blood pressure (BP) control on a sex-specific basis in Africa.

Methods: We undertook a post hoc analysis of the multicenter, randomized CREOLE (Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans) Trial to test the hypothesis that there would be clinically important differences in office BP control between African men and women. We compared the BP levels of 397 and 238 hypertensive women (63%, 50.9 ± 10.5 years) and men (51.2 ± 11.3 years) from 10 sites across …

Accessing Antenatal Care When You Are Rough Sleeping: Barriers And Enablers, Lisa Wood, Natalie Bogoias

IHR Papers and Journal Articles

No abstract provided.

Nurses Leading Volunteer Support For Older Adults In Hospital: A Discussion Paper, Rosemary Saunders, Kate Crookes, Karen Gullick, Olivia Gallagher, Karla L. Seaman, Debra Scaini, Seng G.M. Ang, Caroline Bulsara, Beverley Ewens, Jeff Hughes, Beverly O'Connell, Christopher Etherton-Beer

IHR Papers and Journal Articles

Background

The ageing population has led to growing numbers of older adults in hospital. Given the increased care needs of older adult patients, hospitals are facing resource challenges to ensure patient safety and quality of care. Support from trained volunteers focussed on older adults needs, such as eating, drinking, ambulation and cognitive stimulation have been found to improve patient outcomes.

Aim

This discussion paper describes a novel nurse-led model of volunteer support providing individualised supportive care for hospitalised older adults.

Methods

Discussion paper.

Findings

Nurses’ clinical expertise, 24 hour care and leadership skills makes them ideally placed to guide support …

Designing And Evaluating Falls Prevention Education With Residents And Staff In Aged Care Homes: A Feasibility Study, Jacqueline Francis-Coad, Tessa Watts, Caroline Bulsara, Anne-Marie Hill

IHR Papers and Journal Articles

Purpose: The purpose of this study was to co-design a falls prevention education programme with aged care home residents and staff and evaluate its feasibility. The intention of providing the education programme was to assist residents to stay safe and mobile whilst reducing their risk of falling.

Design/methodology/approach: A two-phase mixed methods participatory design using a resident (n = 6) and care staff (n = 5) consumer engagement panel, pre- and post-programme resident (n = 35) survey and semi-structured care staff interviews (n = 8) was undertaken in two countries.

Findings: A poster, brochure, video and staff education guide featuring …

Improving Care For Older Patients Visiting Emergency Departments. Are They Receiving Falls Prevention Guideline Care?, Melinda Williamson, Annette Barton, Deborah Edwards, Claire Morrisby, Angela Jacques, Kristie J. Harper

IHR Papers and Journal Articles

Background: The primary objective was to examine whether the Emergency Department (ED) treatment of older adults who fall in Australia is concordant with falls prevention and management clinical guideline care recommendations.

Methods: A retrospective medical records audit was completed for patients 65years and older, who at-tended the ED with a fall and were discharged home. An audit tool was developed from local, national, and international falls clinical guidelines.

Results: One thousand and twenty-seven patients presented following a fall throughout 2020. One hundred and seven patient medical records were audited. Assessment of cognition (94%), medication review (76%) and …

The Association Between Diabetes Mellitus Of Different Durations And Risk Of Pancreatic Cancer: An Australian National Data-Linkage Study In Women, Sitwat Ali, Renhua Na, Karen Tuesley, Katrina Spilsbury, Louise M. Stewart, Michael Coory, Penelope M. Webb, Peter Donovan, Sally-Anne Pearson, Susan J. Jordan, Rachel E. Neale

IHR Papers and Journal Articles

Aims: The bidirectional association between diabetes mellitus (DM) and pancreatic cancer (PC) is established; however, the strength of association between duration of DM and risk of PC needs further investigation.

Methods: We conducted a case-control study nested within a population-based cohort of Australian women established using record linkage. Women diagnosed with PC from July 2007 to December 2013, were matched to five controls based on age and state of residence. DM was defined according to prescription of anti-diabetic medication from administrative prescription data. We used conditional logistic regression to calculate odds ratios (OR) and 95% confidence intervals (CI), adjusted for …

Accuracy Of The Australian National Subacute And Nonacute Patient Classification In Predicting Rehabilitation Length Of Stay For Stroke Survivors Who Are ≥65 Years Of Age And Have Lateropulsion, Jessica Nolan, Erin Godecke, Katrina Spilsbury, Andy Wu, Barbara Singer

IHR Papers and Journal Articles

Background

Lateropulsion is a common impairment after stroke. Regardless of stroke severity, functional recovery is slower in people with lateropulsion, resulting in requirement for longer rehabilitation duration. In Australia, inpatient rehabilitation funding is determined via the Australian National Sub-Acute and Non-Acute Patient Classification (AN-SNAP). AN-SNAP class is determined using age, diagnosis, weighted Functional Independence Measure (FIM) motor score, and FIM cognitive score.

Objectives

To explore accuracy of the AN-SNAP to predict length of stay (LOS) for people with poststroke lateropulsion.

Methods

A retrospective database audit was undertaken. AN-SNAP predicted LOS for each participant was calculated based on 2019 calendar year …

Cardiorespiratory Fitness Is A Risk Factor For Lower-Limb And Back Injury In Law Enforcement Officers Commencing Their Basic Training: A Prospective Cohort Study, Myles C. Murphy, Nicole Merrick, Andrea B. Mosler, Garth Allen, Paola Chivers, Nicolas H. Hart

Physiotherapy Papers and Journal Articles

We aimed to report the epidemiology of lower-limb and lumbosacral injuries in Police Force recruits. We performed a cohort study of Police Force recruits undergoing a six-month training program with prospective injury data collected between 2018 and 2021. Cardiorespiratory fitness was quantified by the beep-test and police-specific-functional-capacity was quantified using a specifically designed physical performance evaluation (PPE) tool. Injury frequency and prevalence were reported. Fifteen percent (n = 180) of study Police Force recruits (n = 1,181) sustained a lower-limb or lumbosacral injury. The six-month training program significantly improved cardiorespiratory fitness (p < 0.001) and functional capacity (p < 0.001). Increased cardiorespiratory fitness at baseline decreased injury risk (OR = 0.8, 95%CI: 0.66–0.97, p = 0.019). Injury rates decreased over time and females were injured significantly earlier than males (HR = 0.70, 95%CI: 0.52 to 0.95, p = 0.021). Interventions that can pre-condition Police Force recruits prior to the commencement of their basic physical training may reduce the number of lower-limb and lumbosacral injuries.

Editorial: Insights In Vector Biology: 2021, Baldwyn Torto, David P. Tchouassi

All Peer-Reviewed Publications

This editorial summarizes collections on the Research Topic “Insights in Vector Biology’’. Vectors of four major tropical diseases including malaria, Chagas, dengue and West Nile were considered. The editorial discusses vectors contributing to residual malaria transmission that reside mainly outdoors and not targeted by indoor vector control interventions, notably, long lasting insecticidal nets and indoor residual spraying; the concept of paratransgenesis- a parasite transmission blocking strategy which uses genetically-modified microbes made to produce antimalarial effectors inside the vector for malaria control; assessment of insecticide resistance in malaria vectors; insecticide resistance in Chagas disease vectors; reproductive biology of the dengue vector; …

Microsporidia: A Promising Vector Control Tool For Residual Malaria Transmission, Tullu Bukhari, Roland Pevsner, Jeremy Keith Herren

All Peer-Reviewed Publications

Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) have resulted in a major decrease in malaria transmission. However, it has become apparent that malaria can be effectively transmitted despite high coverage of LLINs/IRS. Residual transmission can occur due to Plasmodium-carrying Anopheles mosquitoes that are insecticide resistant and have feeding and resting behavior that reduces their chance of encountering the currently deployed indoor malaria control tools. Residual malaria transmission is likely to be the most significant hurdle to achieving the goal of malaria eradication and research and development towards new tools and strategies that can control residual malaria transmission is …

Exploring The Feasibility Of Virtually Delivered Auricular Point Acupressure In Self-Managing Chronic Pain: Qualitative Study, Jennifer Kawi, Chao Hsing Yeh, Nada Lukkahatai, Robin L Hardwicke, Thomas Murphy, Paul J Christo

Faculty, Staff and Student Publications

BACKGROUND: Chronic pain remains highly prevalent. Current pharmacological and non-pharmacological strategies have not adequately managed chronic pain which has contributed to disability and high healthcare costs. With existing challenges in providing adequate pain care and access, we tested vAPA, a virtually delivered, self-management intervention using Auricular Point Acupressure (APA) by mobile app and virtual consultations (telehealth). Our key purpose was to evaluate the feasibility of the vAPA in self-managing chronic pain in preparation for a future randomized controlled trial.

METHODS: We conducted a descriptive, qualitative study evaluating our 4-week vAPA intervention among 18 participants. We used directed qualitative content analysis. …

The Current State Of Fellowship Leadership In Dermatology: Trends In Workforce Demographics And Scholarly Productivity, Steven Idell, David D Mcpherson, Jessica Martin, Andrew Dentino, Luis Ostrosky-Zeichner, Julia V Philley, Paul Mcgaha, Megan Devine, Jacqueline Bronicki, Daniel D Karp

Faculty, Staff and Student Publications

In 2018, The University of Texas Health Science Center-Tyler and University of Texas Rio Grande Valley were invited to develop clinical research units for an existing Clinical and Translational Science Award (CTSA) consortium with the objective to equip medically underserved, economically disadvantaged communities and subsequently to deploy COVID-19 clinical trials in response to a public health emergency.

Comparison Of Two Diet And Exercise Approaches On Weight Loss And Health Outcomes In Obese Women, Brittanie Lockard, Michelle Mardock, Jonathan M. Oliver, Mike Byrd, Sunday Simbo, Andrew R. Jagim, Julie Kresta, Claire C. Baetge, Yanghoon Peter Jung, Majid S. Koozehchian, Deepesh Khanna, Chris Rasmussen, Richard B. Kreider

Research, Publications & Creative Work

Aim: To compare the efficacy of two popular weight loss approaches on weight loss, body composition, and markers of health in sedentary obese women. Methods: In total, 51 sedentary women (age 34.5 ± 7.7 yrs.; weight 90.0 ± 14.5 kg; BMI 34.0 ± 5.1 kg/m2 ; 46.5 ± 7.0% fat) were matched and randomized to participate in the Weight Watchers® Momentum™ (WW) or Curves® (CV) Fitness and Weight Management program for 16 weeks. Participants in the WW group (n = 27) were provided a point-based diet program, received weekly progress checks and counseling, and were encouraged to exercise. Participants in …

Engineered Cord Blood Megakaryocytes Evade Killing By Allogeneic T-Cells For Refractory Thrombocytopenia, Bijender Kumar, Vahid Afshar-Kharghan, Mayela Mendt, Robert Sackstein, Mark R Tanner, Uday Popat, Jeremy Ramdial, May Daher, Juan Jimenez, Rafet Basar, Luciana Melo Garcia, Mayra Shanley, Mecit Kaplan, Xinhai Wan, Vandana Nandivada, Francia Reyes Silva, Vernikka Woods, April Gilbert, Ricardo Gonzalez-Delgado, Sunil Acharya, Paul Lin, Hind Rafei, Pinaki Prosad Banerjee, Elizabeth J Shpall

Faculty, Staff and Student Publications

The current global platelet supply is often insufficient to meet all the transfusion needs of patients, in particular for those with alloimmune thrombocytopenia. To address this issue, we have developed a strategy employing a combination of approaches to achieve more efficient production of functional megakaryocytes (MKs) and platelets collected from cord blood (CB)-derived CD34+ hematopoietic cells. This strategy is based on ex-vivo expansion and differentiation of MKs in the presence of bone marrow niche-mimicking mesenchymal stem cells (MSCs), together with two other key components: (1) To enhance MK polyploidization, we used the potent pharmacological Rho-associated coiled-coil kinase (ROCK) inhibitor, KD045, …

Consumer Reactions To Alcohol Advertising Health Warnings In Ireland: An Experimental Research Study, Vania Filipova

Doctoral

Introduction and Aims As part of several measures to inform consumers about the health risks of alcohol and reduce alcohol consumption, the Irish Government signed into law the Public Health (Alcohol) Act 2018, with Section 13 requiring the implementation of multiple health warnings in all alcohol ads. While health warnings on product labels have been subject to intensive political discussion and academic research, health warnings in alcohol ads have received little attention and empirical support. This doctoral dissertation investigates whether health warnings in alcohol ads can promote cognitive and affective reactions in consumers. Furthermore, this thesis also examines whether the …

Aneuploidy And Sex Concordance Rate Between Cell-Free Dna Analysis From Spent Culture Media Of Preimplantation Embryo And Dna From Whole Embryo With Respect To Different Morphological Grading, Hiroki Sonehara, Ryoya Matsumoto, Naoki Nakayama, Masato Kobanawa, Koki Numata, Akiko Kawasaki, Makio Shozu

Faculty, Staff and Student Publications

PURPOSE: The aneuploidy and sex concordance between cell-free DNA in spent culture media (SCM) and DNA from whole embryo with respect to different morphological grading were examined to evaluate the feasibility of non-invasive preimplantation genetic testing for aneuploidy (niPGT-A).

METHODS: A total of 46 pairs of embryos and corresponding SCM were divided into two groups based on the morphological grade. DNA was extracted from 22 and 24 pairs of low- and high-grade embryos, respectively, and respective SCM followed by chromosomal analysis using next-generation sequencing. Aneuploidy study and sex determination were conducted for both groups, and concordance rates were calculated.

RESULTS: …

Invasive Haemophilus Influenza Type B In An Infant During The Covid-19 Pandemic: The Return Of Diseases We Hoped Never To See Again…, Christy Tabarani, Stephen A Fletcher, Gloria P Heresi, Susan H Wootton

Faculty, Staff and Student Publications

No abstract provided.

Regenerative Medicine Technologies Applied To Transplant Medicine An Update, Astgik Petrosyan, Filippo Montali, Andrea Peloso, Antonio Citro, Lori N Byers, Catherine La Pointe, Mara Suleiman, Alice Marchetti, Eoin P Mcneill, Allison L Speer, Wai Hoe Ng, Xi Ren, Benedetta Bussolati, Laura Perin, Paolo Di Nardo, Vincenzo Cardinale, Jerome Duisit, Alexandra Rose Monetti, John Richard Savino, Amish Asthana, Giuseppe Orlando

Faculty, Staff and Student Publications

Regenerative medicine (RM) is changing how we think and practice transplant medicine. In regenerative medicine, the aim is to develop and employ methods to regenerate, restore or replace damaged/diseased tissues or organs. Regenerative medicine investigates using tools such as novel technologies or techniques, extracellular vesicles, cell-based therapies, and tissue-engineered constructs to design effective patient-specific treatments. This review illustrates current advancements in regenerative medicine that may pertain to transplant medicine. We highlight progress made and various tools designed and employed specifically for each tissue or organ, such as the kidney, heart, liver, lung, vasculature, gastrointestinal tract, and pancreas. By combing both …