Medicine and Health Sciences Commons^™

Is Phentermine/Topiramate Er With Lifestyle Modifications Effective In Achieving Weight Loss In Obese Patients With Comorbidities?, Elizabeth A. Stubbs

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is phentermine/topiramate ER with lifestyle modifications effective in achieving weight loss in obese patients with comorbidities?”

Study Design: A systematic review of three placebo-controlled randomized controlled trials (RCTs) published in English in 2012 or after.

Data Sources: All three studies were found by searching PubMed and were published in peer-reviewed journals. The articles were selected based on ability to answer the proposed question.

Outcome Measured: Percent weight loss was the outcome measured in all three studies. This was measured based on mean percent weight loss from …

Does Dancing Reduce Pain During The First Stage Of Labor?, Mattea M. Krasicky

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence-based medicine (EBM) review is to determine whether or not “Does dancing reduce pain during the first stage of labor?”

STUDY DESIGN: Systematic review of one randomized controlled trial (RCT), one single-blind RCT, and one cohort study.

DATA SOURCES: All articles were published in English in peer-reviewed journals between 2014-2020. The articles were obtained via PubMed, Academic Search Premier, AMED, CINHAL Plus, Health Source: Nursing/Academic Edition, and MEDLINE.

OUTCOMES MEASURED: The outcome measured in all three studies was pain severity during labor. Outcomes were measured using the Visual Analog Scale (VAS) of 0 (no …

Is The Use Of A Port As Opposed To A Picc More Effective In Improving Quality Of Life In Patients Receiving Chemotherapy?, Nicholas Coia

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is the use of a PORT as opposed to a PICC more effective in improving quality of life in patients receiving chemotherapy?”

Study Design: Review of three randomized control trials (RCTs) including one monocentric RCT, one two-centre RCT, and one multi-centered RCT.

Data Sources: All articles were published in English and taken from peer-reviewed journals using PubMed. All articles were published between 2014-2020 and chosen based on their relevance to the clinical question.

Outcome Measured: The outcome measured was quality of life (QoL). The studies used …

Is Extended-Release Amantadine Effective At Treating Levodopa- Induced Dyskinesia In Parkinson’S Disease Patients?, Maegan M. Mendoza

PCOM Physician Assistant Studies Student Scholarship

Objective: "The objective of this selective EBM review is to determine "Is extended-release amantadine efficacious in treating levodopa-induced dyskinesia in Parkinson's disease patients?”

Study Design: A systematic review of three randomized controlled trials (RCT's) that were peer-reviewed and published in English after 2010.

Data Sources: All data sources were discovered in PubMed, NLM Catalog, EMBASE, and CINAHL. All articles were published in English in peer-reviewed journals and selected based on applicability to the clinical question and whether the outcomes were patient-oriented.

Outcome Measured: The primary outcome measure was a change from baseline in the Unified Dyskinesia Rating Scale total scores …

Does Lisdexamfetamine Dimesylate (Vyvanse) Reduce The Weekly Incidence Of Binge Eating In Adults With Binge Eating Disorder?, Krista L. Helveston

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does lisdexamfetamine dimesylate (Vyvanse) reduce the weekly incidence of binge eating in adults with binge eating disorder?”

Study Design: A systematic review of three double-blind, randomized, placebo-controlled trials published between 2015 and 2017.

Data Sources: All articles were obtained from PubMed and were published in peer-reviewed journals, in the English language. They were selected based on their applicability to the clinical question, credibility, and if the researched outcomes were patient oriented.

Outcomes Measured: The number of binge eating days per week was the outcome measured, with …

Does The Use Of Aromatherapy Massage Reduce Agitation In Elderly Patients With Dementia?, Nicole A. Frinzi

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does the Use of Aromatherapy Massage Reduce Agitation in Elderly Patients with Dementia?”

Study Design: A systematic review of two randomized controlled trials (RCTs), and one cohort study published between 2010 and 2020.

Data Sources: All studies were discovered using PubMed. The articles were published in English in peer-reviewed journals and selected based on relevance to the clinical question.

Outcome Measured: The outcome measured was a reduction in agitation symptoms. Outcomes were measured through the Cohen-Mansfield Agitation Inventory (CMAI). A similar scale was used among all …

Is The Use Of A Sustained-Release Intracanalicular Dexamethasone Depot An Effective Treatment For Pain Reduction Following Cataract Surgery?, Camille D. Montgomery

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is the use of a sustained-release intracanalicular dexamethasone depot an effective treatment for pain reduction following cataract surgery?”

Study Design: A systematic review of three randomized controlled trials (RCTs) all published between 2015 and 2019.

Data Sources: Two RCTs were discovered using PubMed, and one RCT was discovered using Semantic Scholar. The articles were published in peer-reviewed journals in the English language and selected based on relevance to the clinical question.

Outcome Measured: Absence of pain at day 8 following cataract surgery was a primary outcome …

Is Tranexamic Acid Effective In Reducing Postoperative Blood Loss In Adult Patients With Lumbar Degenerative Disease Who Are Undergoing Posterior Lumbar Spinal Fusion Surgery?, Natalie L. Cervelli

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is tranexamic acid effective in reducing postoperative blood loss in adult patients with lumbar degenerative disease who are undergoing posterior lumbar spinal fusion surgery?”

STUDY DESIGN: A review of two double-blinded randomized controlled trials (RCT) and one RCT.

DATA SOURCES: All articles were peer-reviewed and published in English between 2017-2020. They were found through PubMed and chosen based on ability to answer the objective.

OUTCOMES MEASURED: The outcome measured in all articles was the objective amount of blood loss in mL contained in drainage output through …

Does Preoperative Therapy Improve Function In Postoperative Patients Undergoing Total Knee Arthroplasty?, Ethan A. Carey

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not using “preoperative therapy can improve function in postoperative patients undergoing Total Knee Arthroplasty?”

Study Design: A review of three double-blinded randomized control trials (RCT) that were peered reviewed after 2014

Data Source: All articles were published in peer-reviewed journals and were researched using PubMed. Studies were selected based on their ability to answer the question posed in the objective, and if the researched outcomes were patient oriented.

Outcomes: Assessed outcomes were either from a Timed Up and Go test or Stair Climbing Test.

Results: Joaquin Calatayud …

Does Music Therapy Reduce Distress In Pediatric Oncology Patients?, Kathryn E. Bagnardi

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Does music therapy reduce distress in pediatric oncology patients?”

STUDY DESIGN: A systematic review of three randomized controlled trials (RCTs). All studies were published in English between 2010 and 2017.

DATA SOURCES: Three RCTs were obtained from PubMed and published in peer reviewed journals. The studies were chosen based on their relevance to the clinical question and their inclusion of patient-oriented outcomes (POEMS).

OUTCOMES MEASURED: In all of the articles used for this review, the main outcome measured was distress reduction. The participants’ level of distress …

Does Gua Sha Therapy Reduce Pain Intensity In Patients With Chronic Back Pain?, Anh Y. Cao

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine “Does Gua shatherapy reduce pain intensity in patients with chronic back pain?”

STUDY DESIGN: A systematic review of three randomized controlled trials/studies published in English between 2013-2019.

DATA SOURCES: All articles were published in peer-reviewed journals and obtained from PubMed. The studies were selected based on their applicability to the topic listed above.

OUTCOMES MEASURED: A common outcome measured across all three articles included pain intensity. Each study used the 100 mm Visual Analog Scale (VAS). Participants were asked to rate their pain before and after therapeutic interventions. A …

Is Acupuncture Effective In Improving Pain In Patients With Knee Osteoarthritis?, Despina Lianidis

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Is acupuncture effective in improving pain in patients with knee osteoarthritis?”

Study design: A systematic review of three randomized controlled trials (RCTs) published in between 2015-2018.

Data sources: All three RCTs were discovered using PubMed. The articles were published in English in peer-reviewed journals and selected based on applicability to the clinical question.

Outcome measured: Based on the studies done by Lin et al. and Chen et al., using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), a self-reported measure of lower extremity pain, stiffness, …

Does Exercise Decrease The Level Of Anxiety In Adults?, Alexa N. Wister

PCOM Physician Assistant Studies Student Scholarship

 Objective: The objective of this selective EBM review is to determine whether or not “Does exercise decrease the level of anxiety in adults?”

Study Design: A systematic review of three randomized controlled trials (RCTs) that were peer reviewed and published between 2016 and 2020.

Data Sources: All articles were published in peer-reviewed journals. Two of the RCTs were researched using Pubmed and one RCT was found using Academic Search Premier, AMED. All studies were selected based on applicability to the clinical question presented in the objective, and if the researched outcomes were patient oriented.

Outcome Measured: A reduction in anxiety …

Are Quarterly Fremanezumab Injections As Effective As Monthly Fremanezumab Injections At Reducing The Number Of Migraine Days Per Month In Adults With Chronic Migraines?, Elaine Mellinger

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic EBM review is to determine “Are quarterly fremanezumabinjections as effective as monthly fremanezumab injections at reducing the number of migraine days per month in adults with chronic migraines?”

STUDY DESIGN: A systematic review of three randomized controlled trials (RCTs) that were peer reviewed and published in English after 2015 comparing quarterly versus monthly fremanezumab injections in adults 18-70 with chronic migraines.

DATA SOURCE: Three RCTs were obtained from PubMed and selected based on their relevance to the clinical question and if the RCTs addressed patient oriented outcomes.

OUTCOMES: The three selected RCTs for review, …

Does Endometrial Scratching Increase Live Birth Rates For Women Undergoing Ivf?, Caitlyn Kratzer

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Endometrial Scratching Increases Live Birth Rates for Women Undergoing IVF?”

STUDY DESIGN: A systematic review of three randomized control trials (RCTs) published between 2010 and 2017.

DATA SOURCES: All three RCTs were discovered using PubMed. Studies were published in English in peer-reviewed journals and selected based on applicability to the clinical question.

OUTCOMES MEASURED: In all three articles, the main outcome that will be reviewed is live birth rate. This was measured by the number of live births per embryos transferred divided by the total number …

Is Exercise Effective In Improving The Cognitive And Behavioral Executive Functions In Children Diagnosed With Adhd?, Cara Scatena

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine “Is exercise effective in improving the cognitive and behavioral functions in children diagnosed with ADHD?”

Study Design: A systematic review of three randomized control trials (RCTs). All three of these studies were published between 2011 and 2016.

Data Sources: All three of the RCTs were found using PubMed. All of the studies were published in English in peer-reviewed journals and selected based on their relevance to the clinical question.

Outcome Measured: The outcome measured in these studies is the measurable improvement in executive functions related to the effects of …

Is Aquatic Therapy An Effective Treatment For Reducing Fatigue In Adult Females Living With Ms?, Hanna L. Ozarski

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine, “Is aquatic therapy an effective treatment for reducing fatigue in adult females living with MS?”

Study Design: A systematic review of three randomized controlled trials (RCTs) published between 2015 and 2018.

Data Sources: All three RCTs were published in English peer reviewed journals and were discovered on PubMed using selective search criteria. Studies were chosen based on their relevance and competency to answer the clinical question proposed.

Outcome Measured: The main outcome of focus in each of the articles selected for this review was fatigue reduction. Outcomes were measured …

Is Perioperative Intravenous Lidocaine A Sufficient Adjunct To Traditional Opioid Therapy At Decreasing Post-Operative Pain In Male And Female Patients Ages 18-75 Following A Laparoscopic Cholecystectomy?, Desiree Malacusky

PCOM Physician Assistant Studies Student Scholarship

 OBJECTIVE: The objective of this systematic review is to determine “Is perioperative intravenous lidocaine a sufficient adjunct to traditional opioid therapy at decreasing post operative pain in male and female patients ages 18-75 following a laparoscopic cholecystectomy?”

STUDY DESIGN: A review of three randomized control trials (RCTs) that were peer reviewed and published in English after 2015.

DATA SOURCE: All articles were published in peer reviewed journals and were researched using PubMed and EBSCO databases. Studies were selected based on their ability to answer the question posed in the objective, and if the researched outcomes were patient oriented.

OUTCOMES: The …

Does The Application Of Kt Tape Decrease Pain In Chronic Low Back Pain?, Jordan Vitelli

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine “Does the application of KT tape decrease pain in chronic low back pain?”

Study Design: A systematic review of three randomized controlled trials (RCTs) published between 2018 and 2019.

Data Sources: The three RCTs were published in English in peer reviewed journals and obtained from PubMed. The studies were selected based on their relevance to the clinical question.

Outcome Measured: The outcome measured within all three RCTs was pain intensity using the Visual Analog Scale (VAS). The VAS scoring ranges from 0 to 10, defining 0 as no pain …

Does The Use Of Docosahexaenoic Acid (Dha) Supplementation Decrease The Rate Of Cognitive Decline, As Measured By The Adas-Cog Scale, For Patients With Alzheimer’S Disease?, Erin C. Nakamura

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does the use of docosahexaenoic acid (DHA) supplementation decrease the rate of cognitive decline, as measured by the ADAS-Cog scale, for patients with Alzheimer’s Disease?”

Study Design: A systematic review of three randomized controlled trials (RCTs) published between 2010 and 2018.

Data Sources: All three RCTs were published in English into peer reviewed journals and discovered via PubMed. The studies were selected based on relevance and ability to answer the clinical question.

Outcome Measured: Cognitive function is the outcome measured using the Alzheimer Disease Assessment Scale- …

Is Cryoanalgesia An Effective Supplemental Method Of Post-Thoracotomy Pain Management?, Jency Boyce

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this EBM review is to determine if cryoanalgesia is an effective addition to pain management protocols for patients post-thoracotomy.

Study Design: This EBM review examines three randomized controlled trials.

Data Sources: Data was gathered from the three studies found on PubMed and EBSCOhost. Each study was published in a peer reviewed journal, in English between 2010 and 2021.

Outcome Measured: The outcome measured was pain reported by patients using a visual analag scale (VAS). Two studies utilized a 0-10 scale and the third a 0-100mm scale.

Results: In the study by Sepsas et al. it was …

Does Biofeedback Increase Gait Velocity In Children With Cerebral Palsy?, Kara L. Steck

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does biofeedback increase gait velocity in children with cerebral palsy (CP)?”.

Study Design: A systematic review of three randomized control trials (RCTs) published between 2014 and 2019.

Data Sources: All three RCTs were found using PubMed. Each article was published in English in peer reviewed journals and selected based on their applicability to the clinical question, provide a new technique in CP rehabilitation, and include patient-oriented outcomes (POEMS).

Outcome Measured: The outcome measured was gait velocity before and after treatment using Tekscan software, 3D motion analysis …

Do Probiotics Decrease Depressive Symptoms In Patients With Low Mood?, Kaitlyn Talt

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine, “Do probiotics decrease depressive symptoms in patients with low mood?”

Study Design: A systematic review of three double blind, randomized control trials (RCTs) published between 2016 and 2019.

Data Sources: All three RCTs were found using PubMed and published in English in peer-reviewed journals. The articles were chosen based on their attention to patient-oriented evidence that matters (POEMS) and their relevance to the clinical question.

Outcome Measured: All three articles utilized either the Beck Depression Index (BDI) and/or the Depression Anxiety Stress Scale (DASS) to measure the severity of …

Does High-Flow Oxygen Therapy Decrease The Length Of Hospital Stay In Pediatric Patients With Bronchiolitis When Compared To Standard Oxygen Therapy?, Liann N. Tran

PCOM Physician Assistant Studies Student Scholarship

 OBJECTIVE: The objective of this selective EBM review is to determine, “Does high-flow oxygen therapy decrease the length of hospital stay in pediatric patients with bronchiolitis when compared to standard oxygen therapy?”

STUDY DESIGN: A systematic review of randomized controlled trials (RCTs). All studies were published in the English language after 2014.

DATA SOURCES: All articles were found using PubMed, CINAHL, Alt HealthWatch, AMED. All articles were published in peer-reviewed journals.

OUTCOMES MEASURED: A reduction in length of hospital stay, in terms of the number of days, was the outcome measured in all three studies. This is defined as the …

Does The Use Of Blinatumomab Improve The Overall Survival Rate In Adults With Relapsed/Refractory Acute Lymphoblastic Leukemia?, Julia Colangeli

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review paper is to determine whether or not, “Does the use of blinatumomab improve the overall survival rate in adults with relapsed/refractory acute lymphoblastic leukemia?”

Study Design: A systematic review of two RCTs and one case-based series were utilized. All studies were published between 2014-2019.

Data Sources: The two RCTs were found through PubMed and the case-based series was obtained through CINAHL Plus. All the studies were published in peer-reviewed journals.

Outcomes Measured: The main outcome measured in all the studies was overall survival. Both RCTs defined overall survival as the time from …

Does Spaced Retrieval Therapy Help Improve Quality Of Life For Individuals With Dementia?, Simone E. Fleary

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic EBM review is to determine “Does Spaced Retrieval Therapy Help Improve Quality of Life for Individuals with Dementia?”

Study Design: A systemic review of three peer-reviewed randomized controlled trials (RCT) published in English between 2016-2017.

Data Sources: All peer-reviewed articles were selected using PubMed. All articles were published in English and selected based on relevance to the clinical question. Exclusion criteria excluded studies with combined intervention methods.

Outcome Measured: Assessment of instrumental activities of daily living (IADL) was determined using the IADL task score assessed by the recruiter. Improvement of hyperphagic behavior assessed by …

Does Dance Therapy During Active Labor Reduce Labor Pain?, Sarah E. Naber

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine “Does dance therapy during active labor decrease labor pain?”

STUDY DESIGN: A systematic review of two randomized control trials and a cohort study that were published in English between 2014 and 2020.

DATA SOURCES: Three studies were obtained from PubMed, Alt HealthWatch, and AMED. They were all published in peer-reviewed journals and chosen based on their relevance to the clinical question proposed.

OUTCOMES MEASURED: The main outcome measured in all three studies is pain during active labor. Pain was measured in all studies using the visual analog scale (VAS). …

Is Cryotherapy With Exercise Therapy More Effective Than Exercise Therapy Alone In Reducing Symptoms Associated With Ankylosing Spondylitis?, Michelle Hand

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic EBM review is to determine “Is Cryotherapy with Exercise Therapy More Effective than Exercise Therapy Alone in Reducing Symptoms Associated with Ankylosing Spondylitis?”

Study Design: A comprehensive review of three randomized controlled trials (RCTs).

Data Sources: PubMed database was used to find all three articles referenced in this review. Each article was published in a peer-reviewed journal and published after 2010.

Outcome Measured: The outcome considered for this review was subjective reduction in disease activity measured using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) which consists of 6 questions regarding clinical manifestations of …

Is Platelet Rich Plasma (Prp) Injection An Effective Therapy In Improving Patient Functional Outcomes And Decreasing Pain Postoperatively In Adults With Meniscal Repairs?, Paige A. Foschi

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine: “Is platelet rich plasma (PRP) injection an effective therapy in improving patient functional outcomes and decreasing pain postoperatively in adults with meniscal repairs.”

Study Design: A systematic review of three randomized controlled trials (RCTs) published between 2018 and 2019.

Data Sources: All three RCTs were discovered using PubMed, AMED, CINAHL Plus, and Rehabilitation & Sports Medicine Source. The articles were published in English in peer-reviewed journals and selected based on applicability to the clinical question.

Outcome Measured: Patients’ pain was assessed using the Visual Analog Scale (VAS) and the …

Does Atomoxetine Improve Inattentiveness In Adults With Attention-Deficit Hyperactivity Disorder?, Sarah Defelice

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review of three composite studies is to determine whether or not atomoxetine improves inattentiveness in adults with attention-deficit hyperactivity disorder (ADHD)?

Study Design: A systematic review of three blinded randomized controlled trials (RCTs) published between 2011 and 2021.

Data Sources: Research was gathered from PubMed and Embase in December 2020-February 2021 for the three RCTs, and supplemental articles were found in September through November 2021 from PubMed. All three RCTs were published in English and found in peer-reviewed journals and were chosen based on their relevance to the topic question.

Outcome Measured: A …