Medicine and Health Sciences Commons^™

Rural Community Park Accessibility, Ashleymarie Patricia Hirdler

Occupational Therapy Capstones

Title: Rural Community Park Accessibility

Background: Play is a primary occupation for children and is critical for development (Yogman et al., 2018). School readiness and relationships with others can be impacted when opportunity for play is limited. Play also benefits adults by reestablishing their passion for activities and reducing stress responses to everyday events (Yogman et al., 2018). Lynch et al. (2019) found that when playgrounds were not accessible, children and parents with disabilities felt odd and experienced increased stress due to limited opportunities. It is important for children and their families to have access to accessible parks and spaces …

Educating The Interprofessional Team And Family About Sensory Challenges Children With Autism Spectrum Disorder May Experience, Delanie Vitosh

Occupational Therapy Capstones

Introduction: Children with autism spectrum disorder (ASD) often demonstrate difficulties processing and interpreting sensory input experiencing over-responsiveness or under-responsiveness to sensory stimulation (Autism Speaks, n.d.). A sensory education program was created to educate the interprofessional team and families about sensory challenges children with ASD experience and what strategies can be used to prevent or decrease the number of outbursts caused by over-stimulation, under-stimulation, and their potential impact on participation in meaningful occupations. Based on the literature review, non-compliance with home programs is a major factor negatively affecting therapeutic outcomes (Rone-Adams, Stern, & Walker, 2004). However, Koegel, Bryan, Su, Vaidya, and …

Iris Clubhouse: Experiences Of Community Integration, Rebecca J. Reeves

Occupational Therapy Capstones

The lived experience of community integration for those living with a serious mental illness (SMI) who are members of an unaccredited Clubhouse is an under investigated topic. The goal of this study is to better understand this phenomenon to inform the development of efficient and effective community integration programming for a local Clubhouse who is working toward becoming accredited. 15 active and inactive members of a local Clubhouse participated in a semi-structured interview to discuss their experiences of community integration while living with an SMI. The interviews were analyzed using a hermeneutic phenomenological approach (Dibley et al., 2020). Seven themes …

An Investigation Of Hhv6'S Impact On The Cognitive Progression And Microglial Changes In An Alzheimer's Disease Cohort, Charles E. Seaks

Theses and Dissertations--Physiology

The role of herpesviruses and, more specifically, HHV6 in the development of Alzheimer’s disease (AD) and associated cognitive decline is still being investigated. High ubiquity and prevalence in the population have led to a high degree of skepticism about HHV6 as a potential contributor to cognitive decline and dementias. However, recent evidence related to another herpesvirus, herpes simplex virus 1, suggests that reactivation, not carriage, of the virus may be the key factor to explain the dissonance between the virus’ ubiquity and contributions to dementias. With that in mind, we set out to assess cases from the Sanders-Brown Center on …

Does Attachment Predict Coping Strategies? An In-Depth Look At Millennials During Covid-19, Clinton Johnson

Art Therapy | Master's Theses

Individuals form attachments during the early stages of their lives, with the caregiver serving as their first attachment figure. An individual's attachment style may predict how an individual will react to challenges in life. Responses to challenges may be either adaptive (solution-focused) or maladaptive (solution-avoidant). The objective of this study was to examine how millennial adults demonstrate adaptive coping skills across attachment styles. This unique study explored the relationship between attachment style and coping strategies among five millennial adults. Participants were recruited through convenience sampling via social media and were included if they met the criteria of being a millennial …

Medication Usage In Independent Living: A Continuing Care Retirement Community Aging In Place Initiative, Aarti Deshpande, Carrie B Rubenstein, Ruth Benfield, Lee Burnside

All Poster Presentations

Purpose: The purpose of the study was to identify medication use concerns in this community.

Background: In this study, Swedish Geriatric Medicine Fellow partnered with this community to identify medication use concerns in this population.

Continuing Care Retirement Communities (CCRCs) are intended to support residents as they age in place. These communities tend to be well resourced but less studied. This survey attempts to identify medication use concerns in this population. Mirabella CCRC has 324 Independent living (IL) residents, 82 of which are couples. The average age is 85 years. The current cost of an IL unit is from $4673- …

Psychometric Characteristics And Validity Of The Promis Cancer Function Brief 3d Profile, Sean R. Smith, Mary Vargo, David S Zucker, Samman Shahpar, Lynn Gerber, Maryanne Henderson, Gina Jay, Minji Lee, Andrea Cheville

All Poster Presentations

Purpose: To develop an item response theory (IRT)-calibrated patient-reported outcome measure (PRO) that assesses cancer patient physical function, fatigue and social participation.

Problem Statement: The subspecialty of cancer rehabilitation medicine (CRM) has to date lacked a psychometrically validated patient-reported outcome measure that assesses patients’ physical function, fatigue, and social participation. A significant proportion of the 16.9 million US cancer survivors will experience, or have already experienced, impairments that compromise function, a predictable consequence of their disease and treatment. While each disease site and line of treatment may be associated with unique impairments, there are some that cut across several cancers …

Implementation Of New Policy Software To Enable Quick Access To Best Practice Resources, Mary Alice Duthie, Debbie Shuster

All Poster Presentations

Purpose: Transition to a new policy software that would enable staff to quickly as easily locate Swedish policies and provide policy authors with a practical tool to work more efficiently on policy revisions.

Background/Significance: Existing policy software for Swedish had limited search functionality that caused issues with staff not being able to locate policies quickly or easily. This outdated software had been in place from 2007 – 2021 and contained only basic operations that remained unchanged during this time. If staff had difficulty finding policies in the software then there was the potential for either relying on others on the …

Journal Of The Arkansas Academy Of Science - Volume 76, 2022, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Distal Urogenital Anatomy In The Male Wood Frog, Lithobates Sylvaticus (Anura: Ranidae), Stanley E. Trauth

Journal of the Arkansas Academy of Science

I investigated the microanatomy of the distal urogenital system of the male Wood Frog (Lithobates sylvaticus) from a small sample (n = 6) collected in northern Arkansas in February 2020. Specifically, my primary objectives were as follows: 1) to focus on the histology of the paired Wolffian (urogenital) ducts caudally from the kidneys to their merging with the urodeum of the cloaca, 2) to reveal the structure of the paired seminal vesicles (sperm storage structures), and 3) to compare epithelial morphologies between the distal urogenital tract and its neighboring distal alimentary tract. This information will promote a clearer …

A Study Of Dental Pathology In River Otters (Lontra Canadensis) In Arkansas, C. Renn Tumlison, Jimmie Harper, Karson Grant

Journal of the Arkansas Academy of Science

River otters (Lontra canadensis) consume a variety of foods, including mussels, fishes, and crayfishes. These foods have hard body parts that cause wear of the teeth as the predator ages and incurs more damaging feeding experiences. This can lead to exposure of the pulp cavity and possible abscess and resorption of bone around the alveolus. Further, strong bites against harder parts of prey sometimes results in mechanical breakage, which can lead to pulpitis and severe pathology leading to tooth loss. We investigated the frequency of different forms of dental issues in a sample of 178 skulls of river …

Business Meeting Report (Secretary's And Treasurer's Report), Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Instructions To Authors, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Blood Administration Documentation Audit Automation, Tonya Lawson, Harriette Lober, Andrea Nordmark

All Poster Presentations

Background: Blood administration is a high risk, low volume, complex procedure. It has strict regulatory requirements for documentation of at least 15 elements over the course of the procedure. There are frequently findings for deficient documentation during survey. Manual audits are time consuming and inaccurate. Every facility in the Providence system faces the same challenges to audit for compliance.

Problem: Detecting the rate of compliance for documentation of blood administration manually is difficult. Nursing documentation for blood administration is often incomplete. Manual audits are labor-intensive and have proven to have limited impact to increase documentation compliance.

Methods: We created an …

Write Night: How A Writing Accountability Group (Wag) Supports Scholarly Work And Connection At A Community Residency Program, Carrie B Rubenstein, Claire Thomson, Miranda D Lu, Anna Mcdonald, Karl Dietrich

All Poster Presentations

Purpose: The purpose of this innovative endeavor was to improve scholarly output and collaboration at the Swedish First Hill Family Medicine residency by establishing a Writing Accountability Group (WAG).

Background: While scholarly work during residency training is both required by the ACGME and important for producing physician leaders, many community-based residency programs have no formal structure to support such work and promote collaboration. At our program, faculty worked in functional silos and found it difficult to consistently involve residents in scholarly projects. WAGs have been studied in a variety of settings as a tool to increase scholarly output, improve writing …

Emergency Department Operational Strategies, Joyce W. Davis

Walden Dissertations and Doctoral Studies

AbstractEmergency Department Operational Strategies by Joyce W. Davis MBA/MHA, Pfeiffer University, 2011 BS, North Carolina A&T State University, 1980

Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Business Administration

Walden University December 2022

The Correlation Between Staffing Hours And Nursing Home Resident Fall Rate, Nduka Ikpo Eke

Walden Dissertations and Doctoral Studies

AbstractHealthcare administrators and researchers have had the burden of determining best practice protocols that minimize falls among older adults living in nursing homes for several years. Several studies have investigated, and identified intrinsic and extrinsic factors that lead to falls among other adults and made recommendations along the lines of their findings. However, researchers are yet to establish the impact of staffing hours on nursing home resident fall rate. The purpose of this study was to determine the correlation if any, between nursing home residents fall rate and the staffing hours they receive daily from certified nursing assistants (CNAs), licensed …

Organizational Barriers To Effective University Student Mental Health Services, Felicia Evans-Edwards

Walden Dissertations and Doctoral Studies

This study was focused on organizational barriers to effective university student mental health services access in the department of student resources (DSR) at a for-profit university in the northeastern United States. Once such barriers are addressed, faculty may be more successful in reaching out to students needing mental health services who are not self-identifying as needing these services. The Baldrige excellence framework guided this descriptive case study to examine the organizational barriers that prevent university leadership from creating clear policies and procedures for faculty to refer students to mental health services. Data sources included interviews with the behavioral health leader …

Effects Of Indoor Air Pollutants On Childhood Asthma: African American Parents’ Perspective, Marcia Maureen Haughton Lewis

Walden Dissertations and Doctoral Studies

AbstractIndoor air pollution has been implicated in many chronic health conditions, including childhood asthma, which is more prevalent among African American children. Children are more susceptible than adults to the effects of exposure to indoor air pollution; however, many parents may not be aware of the polluting impacts of products in their homes and are inadvertently placing their families at risk for adverse health outcomes. Understanding parents’ perceptions and experiences is essential for planning and developing educational programs and interventions for improving indoor environment management as part of asthma management in children. This descriptive phenomenological study aimed to explore parents’ …

Challenges And Solutions For Designing A Covid-19 Vaccination Hub: A Simulation Approach, Antonio Cimino, Maria Grazia Gnoni, Francesco Longo, Rafael Diaz, Adriano Solis, Antonio Nervoso, Karen Althea Manfredi, Marika Diaco

VMASC Publications

It is the intent of the work to support experts in the organization process of Covid-19 vaccination hubs. An approach based on Modelling & Simulation (M&S) is proposed and in particular, a simulation model of a real vaccination hub, located in South of Italy, has been developed. The simulation model recreates, with satisfactory accuracy, the evolution over the time of the real system and it has been used to analyze the system behavior under several operative scenarios. The generation of the alternative operative scenarios comes from the variation of multiple design parameters that affect multiple performance measures. The quantitative evaluation …

Perspective On Macroscale Complexity In The National Transplant System, Morgan Stuart, Andrew Placona, Gabe Vece, Kelsi Lindblad, Saikou Diallo, Bob Carrico

VMASC Publications

We present a perspective of the national transplant program based on organizational theory and complexity theory, framing the system’s allocation of donor organs as an interorganizational directed multiplex of agents with diverse belief formation in a cooperative-competitive environment. Simulation and analysis of this macroscale complexity may help explain known behavioural variations across member organizations. However, the transplant community still relies on system-scale simulations since effective macroscale methodologies are not well established. Therefore, we offer this perspective of the national transplant program as a means to stimulate new methods that capture macroscale impacts of policy development for deceased donor organ allocation.

Healthcare 5.0 Security Framework: Applications, Issues And Future Research Directions, Mohammad Wazid, Ashok Kumar Das, Noor Mohd, Youngho Park

VMASC Publications

Healthcare 5.0 is a system that can be deployed to provide various healthcare services. It does these services by utilising a new generation of information technologies, such as Internet of Things (IoT), Artificial Intelligence (AI), Big data analytics, blockchain and cloud computing. Due to the introduction of healthcare 5.0, the paradigm has been now changed. It is disease-centered to patient-centered care where it provides healthcare services and supports to the people. However, there are several security issues and challenges in healthcare 5.0 which may cause the leakage or alteration of sensitive healthcare data. This demands that we need a robust …

Urinary Incontinence In The Pre-Menopausal Woman And Impact On Quality Of Life, Jacqueline Skene Kirk

Theses & Dissertations

Background

Urinary incontinence (UI) is a medical condition that plagues millions of women worldwide, negatively affecting their quality of life. UI is the involuntary release of urine or what women refer to as having “accidents.” Women suffering from UI often feel embarrassed and become socially isolated. The majority of studies in the literature focus on UI in postmenopausal women. However, very few studies explore the lived experience of living with UI as a premenopausal woman, who are at a time in their lives when they are involved in their careers, having intimate relationships with their partners, and are raising their …

Threat Imminence Reveals Links Among Unfolding Of Anticipatory Physiological Response, Cortical-Subcortical Intrinsic Functional Connectivity, And Anxiety, Rany Abend, Sonia G. Ruiz, Mira A. Bajaj, Anita Harrewijn, Julia O. Linke, Lauren Y. Atlas, Anderson M. Winkler, Daniel S. Pine

School of Medicine Publications

Excessive expression of fear responses in anticipation of threat occurs in anxiety, but understanding of underlying pathophysiological mechanisms is limited. Animal research indicates that threat-anticipatory defensive responses are dynamically organized by threat imminence and rely on conserved circuitry. Insight from basic neuroscience research in animals on threat imminence could guide mechanistic research in humans mapping abnormal function in this circuitry to aberrant defensive responses in pathological anxiety.

50 pediatric anxiety patients and healthy-comparisons (33 females) completed an instructed threat-anticipation task whereby cues signaled delivery of painful (threat) or non-painful (safety) thermal stimulation. Temporal changes in skin-conductance indexed anxiety effects on …

Omega-6 And Omega-3 Fatty Acid-Derived Oxylipins From The Lipoxygenase Pathway In Maternal And Umbilical Cord Plasma At Delivery And Their Relationship With Infant Growth, Maranda Thompson, Arzu Ulu, Ana G. Yuil-Valdes, Maheswari Mukherjee, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Elizabeth Lyden, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan

Journal Articles: Pediatrics

Omega-3 and omega-6 fatty acids are important for neonatal development and health. One mechanism by which omega-3 and omega-6 fatty acids exert their effects is through their metabolism into oxylipins and specialized pro-resolving mediators. However, the influence of oxylipins on fetal growth is not well understood. Therefore, the objective of this study was to identify oxylipins present in maternal and umbilical cord plasma and investigate their relationship with infant growth. Liquid chromatography-tandem mass spectrometry was used to quantify oxylipin levels in plasma collected at the time of delivery. Spearman's correlations highlighted significant correlations between metabolite levels and infant growth. They …

Postoperative Breath-Holding Spells Requiring Cardiopulmonary Resuscitation After Cardiopulmonary Bypass, Rebecca Kreis, Jeffrey A. Robinson, Ali N. Ibrahimiye, Laura Ortmann

Journal Articles: Pediatrics

Breath-holding spells are common in childhood and can be associated with bradycardia and pulselessness. This report details severe breath-holding spells complicating postoperative management after atrial septal defect closure. The patient required cardiopulmonary resuscitation despite the use of a temporary pacemaker to prevent bradycardia. After multiple episodes of chest compressions, the decision was made to not intervene immediately to pulselessness and the patient was able to recover without further intervention.

Trajectories Of Medication Non-Adherence With Time-Varying Predictors And Association With Health Outcomes: A Comparison Of Classical Statistical Methods With Machine Learning Algorithms, Vasco Pontinha

Theses and Dissertations

Background: Medication adherence is a major obstacle to improving health care outcomes in long-term therapies for chronic diseases. According to the World Health Organization, interventions for improving medication adherence can have a higher impact on the health of the population than any other advance in medical treatments. Approximately 125,000 individuals die every year in the U.S. because of non-adherence to medication, representing societal costs of $100-289 billion. Previous research has successfully used group-based trajectories methods to identify similar longitudinal medication adherence trajectories. However, medication adherence is not an isolated behavior and is influenced by many factors that current interventions fail …

Cerebrospinal Fluid Levels Of Fatty Acid–Binding Protein 3 Are Associated With Likelihood Of Amyloidopathy In Cognitively Healthy Individuals, Kunal Dhiman, Victor L. Villemagne, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Christopher C. Rowe, Colin L. Masters, David Ames, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins, Veer Gupta

Research outputs 2022 to 2026

Introduction: Fatty acid–binding protein 3 (FABP3) is a biomarker of neuronal membrane disruption, associated with lipid dyshomeostasis—a notable Alzheimer's disease (AD) pathophysiological change. We assessed the association of cerebrospinal fluid (CSF) FABP3 levels with brain amyloidosis and the likelihood/risk of developing amyloidopathy in cognitively healthy individuals. Methods: FABP3 levels were measured in CSF samples of cognitively healthy participants, > 60 years of age (n = 142), from the Australian Imaging, Biomarkers & Lifestyle Flagship Study of Ageing (AIBL). Results: FABP3 levels were positively associated with baseline brain amyloid beta (Aβ) load as measured by standardized uptake value ratio (SUVR, standardized β …

Exploring Discordant Low Amyloid Beta And High Neocortical Tau Positron Emission Tomography Cases, Natasha Krishnadas, Vincent Doré, Simon M. Laws, Tenielle Porter, Fiona Lamb, Svetlana Bozinovski, Victor L. Villemagne, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: Neocortical 3R4R (3-repeat/4-repeat) tau aggregates are rarely observed in the absence of amyloid beta (Aβ). 18F-MK6240 binds specifically to the 3R4R form of tau that is characteristic of Alzheimer's disease (AD). We report four cases with negative Aβ, but positive tau positron emission tomography (PET) findings. Methods: All Australian Imaging, Biomarkers and Lifestyle study of aging (AIBL) study participants with Aβ (18F-NAV4694) and tau (18F-MK6240) PET scans were included. Centiloid < 25 defined negative Aβ PET (Aβ–). The presence of neocortical tau was defined quantitatively and visually. Results: Aβ– PET was observed in 276 participants. Four of these participants (one cognitively unimpaired [CU], two mild cognitive impairment [MCI], one AD) had tau tracer retention in a pattern consistent with Braak tau stages V to VI. Fluid biomarkers supported a diagnosis of AD. In silico analysis of APP, PSEN1, PSEN2, and MAPT genes did not identify relevant functional mutations. Discussion: Discordant cases were infrequent (1.4% of all Aβ– participants). In these cases, the Aβ PET ligand may not be detecting the Aβ that is present.

Dosage, Intensity, And Frequency Of Language Therapy For Aphasia: A Systematic Review-Based, Individual Participant Data Network Meta-Analysis, The Rehabilitation And Recovery Of People With Aphasia After Stroke (Release) Collaborators

Research outputs 2022 to 2026

Background and Purpose: Optimizing speech and language therapy (SLT) regimens for maximal aphasia recovery is a clinical research priority. We examined associations between SLT intensity (hours/week), dosage (total hours), frequency (days/week), duration (weeks), delivery (face to face, computer supported, individual tailoring, and home practice), content, and language outcomes for people with aphasia.

Methods: Databases including MEDLINE and Embase were searched (inception to September 2015). Published, unpublished, and emerging trials including SLT and ≥ 10 individual participant data on aphasia, language outcomes, and time post-onset were selected. Patient-level data on stroke, language, SLT, and trial risk of bias were independently extracted. …