Medicine and Health Sciences Commons^™

Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel

Honors Undergraduate Theses

The COVID-19 pandemic has been an ongoing disaster that has devasted millions of lives. With the development of COVID-19 vaccines in late 2020, there was a potential for populations to gain artificial active immunity in order to prevent future outbreaks. However, despite successful clinical trials, millions of citizens have been hesitant to receive the COVID-19 vaccines (Khubchandani et al., 2021). Demographics of the most prominent US vaccine-hesitant populations consist of ethnic/racial minorities and Republicans groups (Khubchandani et al., 2021). Little information is known about COVID-19 vaccine hesitancy in colleges and universities. Colleges provide an elevated risk for infection through their …

A Retrospective Dosimetry Comparison To Define Uncertainties Found In A Novel Intensity Modulated Electron Therapy (Imet) Treatment Technique For Use In Radiation Therapy, Marco A. Masciantonio

Honors Undergraduate Theses

This study will investigate the difference in radiation at different volumes between traditional electron beam therapy and a novel IMET. The difference in dose will be recorded between the novel IMET and the IMET with a slight shift in the target area. The percent difference between this new model treatment and the model treatment with a shift will be calculated. The main goal of this project is to determine if the target area is still sufficiently treated with this slight shift of the patient in different directions. The percent difference is crucial for the success of this project. It will …

A Systematic Review And Meta-Analysis Of The Relationship Between The Creb Protein's Neuroplastic Functions And The Implications In Neurodegenerative Diseases: A Possible Link Between Synaptic Plasticity And Neurodegenerative Diseases, Mani Sarmast

Honors Undergraduate Theses

In this two-part study, I investigated whether the cyclic-adenosine monophosphate response element-binding (CREB) protein has the potential to be clinically modulated as a therapeutic target for the treatment of neurodegenerative diseases. Part one consisted of a systematic review that was conducted on select articles gathered through a stepwise method to explore (1) the relationship between diseased, neurodegenerative brains and levels of active, phosphorylated CREB (pCREB), (2) increased activation of CREB as a treatment for neurodegenerative symptoms, and (3) a potential therapeutic drug for neurodegenerative diseases that can target CREB signaling. The results of the systematic review showed evidence that suggested …

Efficacy Of Prebiotic Dietary Intervention To Mitigate Risks For Dementia Via The Gut-Brain Axis, Lucille M. Yanckello

Theses and Dissertations--Pharmacology and Nutritional Sciences

Alzheimer’s disease (AD) is the most common form of dementia with various risk factors including age, environmental factors such as brain injury and genetic factors, such as the E4 allele of the Apolipoprotein gene. Presence of the APOE4 allele increases AD risk by two- to four- fold. Recent studies have shown that mild traumatic brain injury (mTBI), even without loss of consciousness, increases risk of dementia diagnosis by more than two-fold in military personnel and is also a significant environmental risk factor for developing dementia in the general population. The gut-brain axis (GBA) or bi-directional communication between the brain and …

The Assessment Of Emergency Preparedness Among University Students, Arliah Cox

All Graduate Theses, Dissertations, and Other Capstone Projects

University students have been an understudied population when it comes to the topic of emergency/ disaster preparedness. While there have been a few studies carried out to examine students’ perceptions of preparedness, the level of preparedness must be determined to be able to close the gap when it comes to barriers preventing them from being prepared. One hundred and eighty-seven undergraduate participants at a Midwestern university completed both online and in-person surveys in March 2022. The survey included questions regarding emergency/ disaster preparedness, perception of being prepared, and barriers which can prevent preparedness. Results showed that a lack of time …

Stereotactic Radiosurgery For Pituitary Adenomas: A Review Of Literature, Kaynat Siddiqui, Saqib Kamran Bakhshi, Muhammad Shahzad Shamim

Section of Neurosurgery

Stereotactic radiosurgery (SRS) is a choice of treatment for pituitary adenomas (PA), particularly for residual or recurrent disease, apart from surgery. It has a progression free survival and endocrine remission rate comparable to surgery, with fewer side effects, making it an ideal tool for dealing with PA. In this review, we have discussed the role of SRS for primary as well as post-operative residual/ recurrent PA, and have assessed its safety and outcomes.

Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.

Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.

Poststroke Seizure And Epilepsy: A Review Of Incidence, Risk Factors, Diagnosis, Pathophysiology, And Pharmacological Therapies, Joseph Phan, Mario Ramos, Theodore Soares, Mayur S. Parmar

HPD Articles

Stroke is the most common cause of epilepsy and ultimately leads to a decrease in the quality of life of those affected. Ischemic and hemorrhagic strokes can both lead to poststroke epilepsy (PSE). Significant risk factors for PSE include age < 65age less than 65 years, stroke severity measured by the National Institutes of Health Stroke Scale (NIHSS), cortical involvement, and genetic factors such as TRPM6 polymorphism. The diagnosis of PSE is made by using imaging modalities, blood biomarkers, and prognostic criteria. Electroencephalography (EEG) is currently the gold standard to diagnose PSE, while new combinations of modalities are being tested to increase diagnostic specificity. This literature review uncovers a newly found mechanism for the pathology of poststroke epilepsy. The pathogenesis of early-onset and late-onset is characterized by sequelae of neuronal cellular hypoxia and disruption of the blood-brain barrier, respectively. Interleukin-6 is responsible for increasing the activity of glial cells, causing gliosis and hyperexcitability of neurons. Epinephrine, high-mobility group protein B1, downregulation of CD32, and upregulation of HLA-DR impact the pathology of poststroke epilepsy by inhibiting the normal neuronal immune response. Decreased levels of neuropeptide Y, a neurotransmitter, act through multiple unique mechanisms, such as inhibiting intracellular Ca accumulation and acting as an anti-inflammatory, also implemented in the worsening progression of poststroke epilepsy. Additionally, CA1 hippocampal resonant neurons that increase theta oscillation are associated with poststroke epilepsy. Hypertensive small vessel disease may also have an implication in the temporal lobe epilepsy by causing occult microinfarctions. Furthermore, this review highlights the potential use of statins as primary prophylaxis against PSE, with multiple studies demonstrating a reduction in incidence using statins alone, statins in combination with antiepileptic drugs (AEDs), and statins with aspirin. The evidence strongly suggests that the second generation AEDs are a superior treatment method for PSE. Data from numerous studies demonstrate their relative lack of significant drug interactions, increased tolerability, and potential superiority in maintaining seizure-free status.

Seasonal Variation In Anthropometric And Performance Variables In American Professional Soccer Players, Hannah Elizabeth Ramirez

College of Graduate Studies: Theses & Dissertations

BACKGROUND: Preseason is an essential component of sport; it prepares players physiologically for the beginning of the competitive season by allowing for improvements in performance and fitness variables. As the season progresses, the need to maintain an ideal performance state may be difficult due to accumulating training load. PURPOSE: The purpose was to determine the seasonal variation of power, agility, and body fat percentage (BF%) via a series of tests throughout the competitive season of American professional soccer players. METHODS: 23 male United Soccer League (USL) One players underwent a performance battery (akimbo vertical jump (VJ), reactive strength index (RSI), …

Becoming A Public Health Professional: Millennials’ Perspective On Organizational Assimilation And Professional Identity, Tony K. Winters

College of Graduate Studies: Theses & Dissertations

ABSTRACT

Public health must confront the ongoing challenge of workforce transitions and the impending exodus of existing employees. The millennial generation rises as an option to fill this workforce gap. Using the Socialization Resource Theory as a framework and qualitative data from in-depth interviews with 27 millennial professionals from federal, state, local, and non-governmental public health agencies, this study describes (a) the organizational assimilation (OA) process for millennial public health professionals, (b) explores the impact of OA on professional identity, and (c) describes how the OA process may impact the retention of public health professionals.

The results from this study …

Elucidation Of Novel And Established Campylobacter Species With Clinical And Agricultural Significance Through Phenotypic, Genotypic, And Taxonomic Investigation, Caoimhe Lynch

Theses

Campylobacter spp. are well-established human, veterinary and economic pathogens, with a broad host range spanning from terrestrial and marine mammalian, avian and reptilian hosts. The scope of the study includes novel and notorious species within the genus, with reference to zoonotic agents Campylobacter jejuni and Campylobacter coli - the leading cause of human bacterial gastroenteritis in the EU and Ireland, Campylobacter fetus that represents the most common campylobacter causing bacteraemia and two novel species isolated from pigs not described in the literature previously. C. jejuni and C. coli isolates (n = 350) recovered from broiler caecal and neck skin samples, …

Gender-Specific Psychological And Social Impact Of Covid-19 In Pakistan, Fauziah Rabbani, Hyder Ali Khan, Suneel Piryani, Areeba Raza Khan, Fahad Abid

Community Health Sciences

Background: COVID-19 has rapidly spread across the world. Women may be especially vulnerable to depression and anxiety as a result of the pandemic.
Aims: This study attempted to assess how gender affects risk perceptions, anxiety levels and behavioural responses to the COVID-19 pandemic in Pakistan, to recommend gender-responsive health policies.
Methods: A cross-sectional online survey was conducted. Participants were asked to complete a sociodemographic data form, the Hospital Anxiety and Depression Scale, and questions on their risk perceptions, preventive behaviour and information exposure. Multiple logistic regression analysis was used to assess the effects of factors such as age, gender and …

Formal Ethics Education In Speech-Language Pathology Graduate Students, Jennifer N. Gaylord

Murray State Theses and Dissertations

Ethical service provision is an essential foundational skill for speech-language pathologists (SLPs) and is fundamental for maintaining the integrity of the profession of speech-language pathology. While practicing speech-language pathologists are required to complete formal ethics training during each certification maintenance interval, there are no guidelines set forth as to the amount and type of training for graduate students in speech-language pathology. This quasi-experimental investigation compared the effect of ethics training embedded within a curriculum to formal ethics training on the ethics knowledge and self-reported comfort levels of first-year graduate students in speech-language pathology. Two equal, non-randomized groups of participants completed …

Examining Patient Demographics Within A Physical Therapy (Pt)-Driven Proning Protocol During Covid-19 Pandemic, Christina Wood, Sidney M. Stoddard Pt, Dpt, Daniel Sawyer Pt, Dpt, Michael Pechulis Dpt, Julie M. Skrzat Pt Dpt Phd Ccs, Mark Fuse, Amanda Fox, Elizabeth A. Wetzler, Mary Loose Pt, Ryan Vetter Ms-Otr/L, Kaitlyn Musco Md, Christopher Lenivy Do, Shae Duka Bs

Department of Medicine

No abstract provided.

Now You See Me, Now You Don’T: Analysis Of The Gold Standard For Portal Vein Thrombosis Diagnosis, William Ghaul

Department of Medicine

No abstract provided.

Schmidt Syndrome Causing Multi-Organ Failure, Emily C. Skutnik Do, Fatima Kutty, Clarissa Hayes, Marc Stezzi Do, Theresa Maitz Do, Shamsuddin Shaik Md

Department of Medicine

No abstract provided.

Prolonged Ocular Foreign Body Found On Repeat Visit To A Second Emergency Department, Conor Mclaughlin, Sara Safari, Avani Shah, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

Managing Chronic Pain With Medical Cannabis: A Chance To Reduce Opioid-Related Ed Visits, Nicholas S. Imperato, Gretchen Maurer, Hope Kincaid Mph, Cph, Joseph E. Patruno Md, Joshua S. Krassen, Robert Wilson, Autumn Kieber-Emmons Md, Mph, Andrew L. Koons

Department of Emergency Medicine

No abstract provided.

Expanded Use Of Point Of Care Ultrasound Curriculum For Attending Physicians, Kristine L. Schultz Md, Hanna R. Warren Do, Kevin R. Roth Do, Facoep, Claire L. Paulson Do

Department of Emergency Medicine

No abstract provided.

Understanding Parents' Experiences With Children With Type 1 Diabetes: A Qualitative Inquiry, Justin A. Haegele, Steven K. Holland, Eddie Hill

Human Movement Studies & Special Education Faculty Publications

Parenting is often described as a stress-inducing experience, which can be further complicated or made more stressful and anxiety-inducing when parenting children with chronic conditions such as type 1 diabetes (T1D). The incidence of T1D among children has risen and continues to rise globally, resulting in a need to understand the experiences of parenting children with T1D. The purpose of this qualitative inquiry was to explore the lived experiences, and the meaning ascribed to those experiences, of being a parent of a child with T1D. This qualitative study was conducted through an interpretivist paradigm and includes the experiences of 29 …

Meeting The 24-Hour Movement Guidelines And Outcomes In Adolescents With Adhd: A Cross-Sectional Observational Study, Wei Wang, Justin A. Haegele, Yandan Wu, Chunxiao Li

Human Movement Studies & Special Education Faculty Publications

According to the 24-Hour Movement Guidelines, meeting daily recommendations for physical activity, sleep, and screen time is important for obtaining optimal health benefits. This cross-sectional observational study aimed to examine (a) the prevalence of meeting the movement guidelines; and (b) the associations between meeting the guidelines and selected outcomes in adolescents with attention-deficit/hyperactivity disorder (ADHD). Data from the 2018–2019 National Survey for Children’s Health dataset was used. Participants were adolescents (10–17 years) with ADHD and without other chronic conditions. Outcomes were flourishing, school engagement, and body weight status. Exposures of interest were adherence to the movement guidelines. The frequency of …

Iranian Parents' Perceptions On Physical Activity For Their Children With Autism Spectrum Disorder During The Covid-19 Pandemic, Sarvin Salar, Justin A. Haegele, Hassan Daneshmandi

Human Movement Studies & Special Education Faculty Publications

Purpose: The COVID-19 pandemic is a remarkable health crisis that enforced most people to stay at home and quarantine for a period of time and seems to be having negative impacts on physical activity and mental health worldwide. Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder with a deficit in social interaction characteristics, relationships, and stereotyped behaviors. This study examined Iranian parents’ perceptions of physical activity for their children with ASD during the COVID-19 pandemic.

Methods: In this study, an explanatory qualitative methodology was used and data were collected via semi-structured phone interviews. The samples included 40 Iranian parents (aged …

Meeting The 24-H Movement Guidelines And Health-Related Outcomes Among Youth With Autism Spectrum Disorder: A Seven-Country Observational Study, Chunxiao Li, Justin A. Haegele, Fenghua Sun, Maria Luiza Tanure Alves, Stefanie Hwee Chee Ang, Jihyun Lee, Kwok Ng, Isabella Dos Santos Alves, Sean Healy, Wendy Yajun Huang, Pauli Rintala, Jernice Sing Yee Tan, Yandan Wu, Hannah Yang, Eija Kärnä, Hyokju Maeng, André Lisandro Schliemann

Human Movement Studies & Special Education Faculty Publications

Background: Meeting daily guidelines for physical activity, screen time, and sleep duration is associated with a host of health indicators for youth. In this cross-sectional observational study, we investigated the associations between adherence to the movement guidelines and health-related outcomes among youth with autism spectrum disorder (ASD).

Methods: Parents of youth with ASD (10-17 years) from seven countries and regions were invited to provide online proxy-reports for child's movement behaviors (i.e., physical activity, sleep and screen time), and health-related outcomes (i.e., body mass index [BMI], general health, and quality of life). A series of multiple linear regression analyses were used …

Exploring Nurse Burnout And Perceived Features For Break Area Support Among Nurses Before And During Covid-19 Pandemic, Sahar Mihandoust, Jamie Roney, Gisele Nicole Bazan, Stephanie Dunkle, Joann Long

Articles, Abstracts, and Reports

No abstract provided.

Improving Neurorepair In Stroke Brain Through Endogenous Neurogenesis-Enhancing Drugs, Kuo-Jen Wu, Seongjin Yu, Jea-Young Lee, Barry Hoffer, Yun Wang

Neurosurgery and Brain Repair Faculty Publications

Stroke induces not only cell death but also neurorepair. De novo neurogenesis has been found in the subventricular zone of the adult mammalian brain days after stroke. Most of these newly generated cells die shortly after the insult. Recent studies have shown that pharmacological manipulation can improve the survival of endogenous neuroprogenitor cells and neural regeneration in stroke rats. As these drugs target the endogenous reparative processes that occur days after stroke, they may provide a prolonged window for stroke therapy. Here, we discuss endogenous neurogenesis-enhancing drugs and review the general status of stroke therapeutics in evaluating the field of …

Evaluating Providers’ Knowledge, Attitudes And Intentions Toward Assessing Pregnancy Desires In Women Of Childbearing Age, Sydney Hahn

DNP Projects

Abstract

Background: Unintended pregnancies account for over half of all pregnancies in the United States. Unintended pregnancies can lead to abortion, socioeconomic difficulties, medical complications, psychological issues, and political issues. Unintended pregnancies are potentially harmful to both the mother and the baby. Healthy People 2030 listed reducing the number of unintended pregnancies as one of their family planning objectives.

Purpose: The purpose of this DNP project was to evaluate providers’ knowledge, attitudes, and intentions toward assessing pregnancy desires in women of childbearing age. Methods: The study was a one-group pre/post intervention design. The data was gathered via a convivence sample …

Assessment Of The Impact Of The Lockdown On The Use Of Medications For Chronic Diseases In The State Of Goa, Sayed Sf, Dias A, Viegas M

Manipal Journal of Medical Sciences

Background: The COVID-19 pandemic came as a shock to citizens globally and those dependent on medications for chronic conditions were hit the hardest during the long lockdowns. This study aims to assess how the medications for chronic conditions in the state of Goa were impacted and the change in practices and attitude towards purchase and compliance.

Methods: It was a cross sectional study conducted on 264 participants from various parts of Goa, a state on the western coast of India. Data was collected using an online questionnaire using Google forms which involved closed and open ended questions assessing attitude, compliance …

How Comprehensive And Effective Are Waste Management Policies During The Covid-19 Pandemic? Perspectives From The Philippines, Geminn Louis C. Apostol, Angelina Gabrielle A. Acolola, Michelle Alexandra Edillon, Sary Valenzuela

Ateneo School of Medicine and Public Health Publications

This study presents a comprehensive analysis on policies governing the management of COVID-19 waste in the Philippines, highlighting gaps in pre-existing policies and opportunities for further policy development and adaptation in the context of present and future public health emergencies. A hybrid search strategy and consultative process identified fifty (50) policy documents directly impacting the management of wastes (general domestic, healthcare, and household healthcare waste) released prior to and during the pandemic. Content analysis revealed comprehensive policy coverage on managing general domestic waste and healthcare waste. However, there remains a dearth in policies for managing household healthcare waste, an emerging …

Outmigration And Unequal Distribution Of Filipino Physicians And Nurses: An Urgent Call For Investment In Health Human Resource And Systemic Reform, Janine Patricia G. Robredo, Bradley Ong, Michelle Ann B. Eala, Raymond John Naguit

Ateneo School of Medicine and Public Health Publications

No abstract provided.