Medicine and Health Sciences Commons^™

School-Based Practitioners' Perceptions Of Working With Students With Challenging Behaviors, Candace Thrash

Occupational Therapy Doctorate Capstone Projects

Background: School-based occupational therapy practitioners must develop a skill set that allows effective service delivery to individuals, groups, and populations in the school setting in order to support students with varying disabilities achieving their occupation-based goals. There is limited research and literature regarding occupational therapy practitioners’ perceptions regarding working with students with challenging behaviors and what they feel has prepared them to work with these students. It is important to determine if additional training, professional development, fieldwork experiences or mentorships are necessary to prepare school-based therapists to manage students effectively and confidently on their caseload who have challenging behaviors.

Purpose: …

Sports Betting Among Rhode Island Young Adults: A Cross-Sectional Study, Jonathan Noel, Samantha Rosenthal, Cara Sammartino

Health & Wellness Department Faculty Publications and Research

Sports betting in Rhode Island was legalized in 2018 after the U.S. Supreme Court decision in Murphy v. National Collegiate Athletic Association. This study assessed the prevalence of sports betting among Rhode Island young adults, identified sociodemographic predictors of sports betting, and tested whether sports betting was predictive of gambling problems. 12.4% of participants (n = 540, 18-25 years old) participated in sports betting, with the odds 3x higher in men, and 2x higher in essential workers. Problem gambling was 2.4x higher among sports bettors. Greater prevention efforts are needed to limit sports betting and prevent problem gambling.

A Comparative Review Of Nutrition Education Intervention Duration And Impact On Reduction Of Prediabetes Or Type 2 Diabetes Mellitus Among Adults Aged 45 Years Or Older, Christa Corgatelli, Elizabeth Dodge, Joshua Bernstein, Joanna Kruk, Basil Aboul-Enein

Health & Wellness Department Faculty Publications and Research

Prediabetes and Type 2 diabetes mellitus (T2DM) is increasingly prevalent and both conditions have a variety of comorbidities. There are many programs aimed at the reduction or prevention of prediabetes and/or T2DM. However, only a few studies have evaluated the effect of intervention duration and evidence-based frameworks on specific populations at risk for prediabetes or T2DM. This review evaluated evidence-based lifestyle intervention programs to determine whether the duration of programming relates to the efficacy of evidence-based lifestyle change interventions. The aim was to assess relevant outcomes of these interventions in prediabetic or T2DM individuals aged 45 and older. The PRISMA …

Degree-Granting Nutrition Programs In The Republic Of Yemen: A Status Report On Postsecondary Education, Miral Mansour, Basil Aboul-Enein, Elizabeth Dodge, Nada Benajiba

Health & Wellness Department Faculty Publications and Research

Yemen is noted as one of the most food-insecure countries in the Arab world coupled with high rates of malnutrition. To address the public health outcomes related to nutrition, trained nutrition professionals are needed. This report provides a snapshot of current nutrition-affiliated programs offered in postsecondary institutions in Yemen. Partnering with or creating independent organizations responsible for defining the scope of practice is warranted. Additionally, ensuring educational quality, program accreditation, and competence of graduating students and readiness to practice will be central to progressively moving Yemen’s dietetics profession forward.

Implementing Nutrition Education Into Physician Assistant Curriculum; What Is The Best Method?, Whitney Temple, Justin Gambini

Doctor of Medical Science (DMSc)

ABSTRACT: Purpose: The primary purpose of this article is to review an effective to implement nutrition education within an already established PA curriculum. Method: The search strategy was devised in consultation with a university medical librarian. Five databases were searched and included PubMed, EBSCO, SCOPUS, Google Scholar and Education Source. The literature search was conducted using subject headings (MeSH), as well as words and phrases, including but not limited to nutrition education, graduate medical education, medical students, physician assistant, nutrition curriculum, lifestyle medicine, culinary medicine and education assessment. The search was conducted from February 2022 through July 2022 and was …

Patient-Centered Focus Groups As A Catalyst For Anti-Racism Research And Quality Improvement In An Urban Academic Ob/Gyn Clinic, Samantha Brenner, Fiona Hodges, Tonia J. Rhone, Toni Tipton, Keith Reisinger-Kindle

Obstetrics and Gynecology Faculty Publications

Background •There is a known, pervasive existence of racism within OBGYN with resultant inequities and disparities in patient outcomes •Limited published perspectives of patients with racism in inpatient and outpatient OBGYN •The importance of centering patients’ voices in anti-racism research initiatives is clear •The objective of this study was to utilize patient-centered focus groups to prioritize anti-racism quality improvement and research investigations in the inpatient and outpatient setting

What Is More Effective: Corticosteroid Injections Or Platelet Rich Plasma Infections In The Treatment Of Lateral Epicondylitis?, Joseph Mohr, Curt Stilp, Justin Gambini

Doctor of Medical Science (DMSc)

ABSTRACT

Lateral epicondylitis is a common degenerative tendinopathy that affects a wide variety of individuals. One patient population that often suffers more than others are workers with manual labor jobs that use vibrating tools and repetitive motions.1 Procedural costs and disease burden associated with lateral epicondylitis have increased in recent years.3 Current treatment of lateral epicondylitis using corticosteroid injections is beginning to fall out of favor. Corticosteroid injections help decrease inflammation; however, research looking into the histology of lateral epicondylitis favors more of a degenerative tendinopathy rather than an inflammatory condtion.1 In addition, several studies have found corticosteroid injections to …

Experience Implementing A Public Health Surveillance System Designed For Fathers Of Infants On A South Dakota American Indian Reservation, Sara Decoteau, Maggie Minett, Teresa L. Binkley, Tianna Beare, Bonny Specker

Ethel Austin Martin Program Publications

Introduction: Paternal behaviors and attitudes during pregnancy are not known. A health survey for fathers of recently born infants was developed to be administered concurrently with a maternal survey to assess parental behaviors and attitudes before, during and after pregnancy.
Methods: Participants were parents of 149 American Indian infants born from April 1 and Dec. 31, 2015 who were recruited prospectively from data of all births in prespecified reservation counties representing Sisseton Wahpeton Oyate of the Lake Traverse Reservation. Data collection was via hard-copy or online survey. Results: Response rate among mothers was 62 percent (n=92). Of 149 births, 126 …

Destination Dental School: A Remote Pipeline Program To Increase Student Diversity, Thikriat Al-Jewair Dds, Ms, Frcd(C), Jessica Scates Med

The New York State Dental Journal

Promoting diversity among dental school applicants and enrollees is key to tackling oral health disparities and improving learning outcomes. Building the pipeline has proven to be an effective method to increase diversity and heighten interest in dentistry among students. Destination Dental School is an 8-week remote pipeline program aimed at increasing diversity of historically underrepresented minority (HURM) students in the field of dental medicine. Pre- and post-program surveys showed that the program was effective in fostering HURM students’ interest in dentistry and increasing their knowledge and preparedness for dental school applications.

A Call To Do Better: Addressing Diversity Within The Dental Profession, Fabiola Milord Dds, Mph

The New York State Dental Journal

Current systems have not been successful in addressing the existing racial inequities between black dental professionals and other racial groups. This group in particular seems to have less visibility and representation in organized dentistry. Nowhere has this been more obvious that during the COVID-19 pandemic whereby African-American professionals were not as prominently featured in offering their viewpoint and expertise. In this paper, insights regarding the topic of diversity are discussed in order to gain perspective into a situation that has existed far too long.

Mechanisms Of Progestin Resistance In Reproductive-Age Women With Atypical Endometrial Hyperplasia, Katherine Mcmaster Cooke

Yale Medicine Thesis Digital Library

With the rising prevalence of endometrial cancer and its precursor atypical hyperplasia (AH) in reproductive-age women amid the obesity epidemic, understanding the pathogenesis of this disease process is crucial to improving medical management. We sought to identify factors that may contribute to progestin-resistant AH via analysis of clinical data as well as investigation of hormonal regulation of endometrial gene and protein expression. We conducted a retrospective review of women with AH (n=63) compared to those with benign hyperplasia (BH) (n=73), which has a significantly lower risk of progression to malignant disease. Subsequently, we analyzed a sub-cohort of women with progestin-responsive …

Fracture Callus Evaluation In The Setting Of Breast Cancer Metastasis And Rescue Of Healing Via Inhibition Of Erk1/2, Christopher Dussik

Yale Medicine Thesis Digital Library

Background: Pathological fractures of the femoral shaft are devastating complications of metastatic breast cancer that afflict a myriad of women worldwide. Those affected suffer from debilitating pain, loss of function, and diminished quality of life. Intramedullary nailing with locking screw fixation provides the foundation of femoral fracture repair. However, cancer-induced changes within the local osseous environment drastically impair normal bone healing, leading to nonunion, reduced quality of life, and delays in medical oncologic care. At this time, comparatively little is known about the underlying mechanisms involved in impaired pathological fracture healing. A more thorough understanding of the influence breast cancer …

Cardiovascular Applications Of Artificial Intelligence In Research, Diagnosis, And Disease Management, Viswanathan Rajagopalan, Houwei Cao

Center for No Boundary Thinking

Despite significant advancements in diagnosis and disease management, cardiovascular (CV) disorders remain the No. 1 killer both in the United States and across the world, and innovative and transformative technologies such as artificial intelligence (AI) are increasingly employed in CV medicine. In this chapter, the authors introduce different AI and machine learning (ML) tools including support vector machine (SVM), gradient boosting machine (GBM), and deep learning models (DL), and their applicability to advance CV diagnosis and disease classification, and risk prediction and patient management. The applications include, but are not limited to, electrocardiogram, imaging, genomics, and drug research in different …

Zip8-Mediated Intestinal Dysbiosis Impairs Pulmonary Host Defense Against Bacterial Pneumonia, Derrick R. Samuelson, Deandra R. Smith, Kelly C. Cunningham, Todd A. Wyatt, Sannette C. Hall, Daryl J. Murry, Yashpal S. Chhonker, Daren L. Knoell

Journal Articles: Environmental, Agricultural & Occupational Health

Pneumococcal pneumonia is a leading cause of morbidity and mortality worldwide. An increased susceptibility is due, in part, to compromised immune function. Zinc is required for proper immune function, and an insufficient dietary intake increases the risk of pneumonia. Our group was the first to reveal that the Zn transporter, ZIP8, is required for host defense. Furthermore, the gut microbiota that is essential for lung immunity is adversely impacted by a commonly occurring defective ZIP8 allele in humans. Taken together, we hypothesized that loss of the ZIP8 function would lead to intestinal dysbiosis and impaired host defense against pneumonia. To …

Sars-Cov-2 Dysregulates Neutrophil Degranulation And Reduces Lymphocyte Counts, Abenaya Muralidharan, Todd A. Wyatt, St. Patrick Reid

Journal Articles: Environmental, Agricultural & Occupational Health

SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been identified as an important correlate to poor recovery rates in severe COVID-19 patients. However, the mechanisms underlying this clinical outcome and the reasons for its correlation to poor prognosis are unclear. Furthermore, the mechanisms involved in healthy neutrophils acquiring a SARS-CoV-2-mediated detrimental role are yet to be fully understood. In this study, we isolated circulating neutrophils from healthy donors for treatment with supernates from infected epithelial cells and direct infection with SARS-CoV-2 in vitro. Infected epithelial cells …

Aldehyde Trapping By Adx-102 Is Protective Against Cigarette Smoke And Alcohol Mediated Lung Cell Injury, Carmen A. Ochoa, Claire Nissen, Deanna Mosley, Christopher Bauer, Destiny Jordan, Kristina L. Bailey, Todd A. Wyatt

Journal Articles: Environmental, Agricultural & Occupational Health

Most individuals diagnosed with alcohol use disorders smoke cigarettes. Large concentrations of malondialdehyde and acetaldehyde are found in lungs co-exposed to cigarette smoke and alcohol. Aldehydes directly injure lungs and form aldehyde protein adducts, impacting epithelial functions. Recently, 2-(3-Amino-6-chloroquinolin-2-yl)propan-2-ol (ADX-102) was developed as an aldehyde-trapping drug. We hypothesized that aldehyde-trapping compounds are protective against lung injury derived from cigarette smoke and alcohol co-exposure. To test this hypothesis, we pretreated mouse ciliated tracheal epithelial cells with 0–100 µM of ADX-102 followed by co-exposure to 5% cigarette smoke extract and 50 mM of ethanol. Pretreatment with ADX-102 dose-dependently protected against smoke and …

Surface Modification Of Biodegradable Microparticles With The Novel Host-Derived Immunostimulant Cpdi-02 Significantly Increases Short-Term And Long-Term Mucosal And Systemic Antibodies Against Encapsulated Protein Antigen In Young Naïve Mice After Respiratory Immunization, Jacob E. Parriott, Jason P. Stewart, D. David Smith, Stephen M. Curran, Christopher D. Bauer, Todd A. Wyatt, Joy A. Phillips, Elizabeth Lyden, Geoffrey M. Thiele, Joseph A. Vetro Phd

Journal Articles: Environmental, Agricultural & Occupational Health

Generating long-lived mucosal and systemic antibodies through respiratory immunization with protective antigens encapsulated in nanoscale biodegradable particles could potentially decrease or eliminate the incidence of many infectious diseases, but requires the incorporation of a suitable mucosal immunostimulant. We previously found that respiratory immunization with a model protein antigen (LPS-free OVA) encapsulated in PLGA 50:50 nanoparticles (~380 nm diameter) surface-modified with complement peptide-derived immunostimulant 02 (CPDI-02; formerly EP67) through 2 kDa PEG linkers increases mucosal and systemic OVA-specific memory T-cells with long-lived surface phenotypes in young, naïve female C57BL/6 mice. Here, we determined if respiratory immunization with LPS-free OVA encapsulated in …

Post-Endotoxin Exposure-Induced Lung Inflammation And Resolution Consequences Beneficially Impacted By Lung-Delivered Il-10 Therapy, Jill A. Poole, Rohit Gaurav, Aaron Schwab, Amy J. Nelson, Angela Gleason, Debra J. Romberger, Todd A. Wyatt

Journal Articles: Environmental, Agricultural & Occupational Health

Although lung diseases typically result from long-term exposures, even a robust, one-time exposure can result in long-lasting consequences. Endotoxin is a ubiquitous environmental/occupational inflammatory agent often used to model airway inflammation. Using a murine model, the return to lung homeostasis following high dose inhalant lipopolysaccharide (LPS, 10-100 μg) exposure were delineated over 2 weeks. LPS-induced rapid weight loss, release of proinflammatory mediators, and inflammatory cell influx with prolonged persistence of activated macrophages CD11c⁺CD11b⁺ and recruited/transitioning CD11c^intCD11b⁺ monocyte-macrophages out to 2 weeks. Next, lung-delivered recombinant (r) interleukin (IL)-10 was intratracheally administered for 3 doses initiated …

College Of Health Professions Research Newsletter: 2021-2022 Academic Year, College Of Health Professions

College of Health Professions Newsletters & Magazines

Contents include: A letter from the CHP Research Committee Chair, Jacqueline A. Vernarelli --A letter from the Editor, Kaylee Quinn -- Faculty peer-reviewed publications, grants, professional presentations, and media interviews.

The Effects Of Atir Blocker On The Severity Of Covid-19 In Hypertensive Inpatients And Virulence Of Sars-Cov-2 In Hypertensive Hace2 Transgenic Mice., Xiaoliang Jiang, Huadong Li, Yong Liu, Linlin Bao, Lingjun Zhan, Hong Gao, Wei Deng, Jing Xue, Jiangning Liu, Xing Liu, Junli Li, Jie Wang, Shuang Wu, Mingzhe Yan, Wei Luo, Pedro A. Jose, Chuan Qin, Xiuhong Yang, Dingyu Zhang, Zhiwei Yang

Medicine Faculty Publications

No abstract provided.

Store, Handle, And Administer Vaccines Safely To Prevent Errors, Craig Kimble, Kenneth Maxik, Alberto Coustasse

Management Faculty Research

Insufficient training, multiple manufacturers, and noninterchangeable products increase the risk of vaccine-related errors. Increasing the complexity are the addition of boosters with different doses, personnel new to the vaccine administration process, changes in dosing, easily misidentified labeling or products, vaccines given together, and the interchanging of booster products.2,3 As a result, there is an increased need to be alert in safety efforts with vaccine administration and storage. Pharmacy staff members must work together to improve safety and prevent vaccine-related errors.

Issues To Publish In Latin America, Fiacro Jiménez Ponce, José Antonio Soriano Sánchez, José Alberto Israel Romero Rangel

Archives of Neurosurgery

Scientific knowledge is essential to the development of civilization, particularly in our case for anatomy and physiology of the central nervous system and neurosurgical practice. In this editorial, we are reviewing three critical aspects of scientific publications: The scientific training of physicians, the impact of publications, and the ethical aspects related to elaborating a paper.

Aneurysmal Subarachnoid Hemorrhage And Acute Subdural Hematoma, Neurosurgical And Endovascular Rescue. Case Report., José Omar Santellan Resident, José Ramón Aguilar Dr., Abraham Ibarra Dr., Ulises García Dr.

Archives of Neurosurgery

Introduction: Acute subdural hemorrhage (aSDH) in association with aneurismal subarachnoid hemorrhage (SAH) is a severe disease with an incidence of 0.5% to 7.9% of all SAH. Due to the rarity of aneurysmal aSDH, it remains difficult to define a comprehensive management protocol. In this case review, following the CARE guidelines, we show the hybrid management of this pathology to know the importance of using different types of neurosurgical treatments in case of two severe diseases in critical patients.

We present two patients who developed sudden onset cephalea and neurological impairment secondary to aneurysmal subarachnoid hemorrhage associated with acute subdural hematoma. …

The Scientific Divulgation In Neurosurgery., Rodrigo Ramos-Zuñiga, Sergio Manuel Ibarra-Navarro

Archives of Neurosurgery

The communication of scientific findings in a young discipline in the evolution of knowledge about the human nervous system, has had a consistent and significant advance. This interdisciplinary and multidisciplinary vision has been a fundamental educational axis in the development of neurosurgery in terms of innovation, scientific progress, technological development and quality of patient care. It is therefore essential that scientific writing and communication channels continue to preserve these quality standards, to validate without bias and with certainty, the value and strength of the advances of neurosurgery as a science.

Passive Functional Mapping Using Infrared Thermography In Epilepsy Awake Surgery: Case Report, Enrique De Font-Réaulx, Javier Terrazo-Lluch, Paul Shkurovich-Bialik, Miguel Ángel Collado-Corona, Ernesto Ramírez-Navarrete, Luis Díaz-López Md, Alma Rosa Martínez-Rosas Msc, Adalberto González-Astiazarán

Archives of Neurosurgery

Background: Active Functional Mapping (AFM) is the gold standard method for localizing cortical and subcortical brain functional areas and tracts. By definition, it requires direct application of controlled electrical stimuli under established protocols. Nevertheless, it entails inherent risks, such as causing intraoperative seizures. On the other hand, Passive Functional Mapping (PFM) doesn´t require electrical stimulation of the nervous system. PFM is based on the knowledge that brain metabolism generates different electromagnetic radiation patterns depending on its metabolism, that are invisible to the human eye, but infrared thermographic cameras can show those changes related to brain activity without the use of …

The Many Worlds Of Neurosurgery And The Labyrinth Of Borges, Juan F. Villalonga, Giulia Guizzardi, Domenico Solari

Archives of Neurosurgery

Nowadays, an apprentice of neurosurgery has to complete long and different pathways of education.The encounter between the schools of Napoli and Tucuman, make us identify a common strategy of neurosurgical education. In attempt of defining the philosophy behind it we attempt a comparison in between the life and training of a modern neurosurgeon and the character of a tale of Borges (i.e. Ts'ui Pên). As neurosurgeons of the 21st century we must be like the inextricable Ts'ui Pên.

L5-S1 Collapsed Space Is Not A Contraindication For Elif. Technical Note And Preliminary Clinical Results, Iris Tatiana Montes González, Sergio Soriano Solis, Manuel Eduardo Soto García, Manuel Rodríguez García, Gerson Reyes Rodríguez., Víctor David López García, José Antonio Soriano Sánchez

Archives of Neurosurgery

INTRODUCTION: Extraforaminal lumbar interbody fusion (ELIF) avoids vascular, neural, and genitourinary risks of anterior and lateral techniques. However, many authors consider ELIF to be contraindicated in L5-S1, especially in the case of a collapsed space. Therefore, we aim to provide a technical note for ELIF in the context of an L5-S1 collapsed space and present our experience and the postoperative clinical results of our patients. MATERIALS AND METHODS: We collected data from the records of patients with ELIF L5-S1 level collapsed between March 2020 to June 2021, using for this study sex, age, clinical symptoms, diagnosis, L5-S1 height space, EVA, …

Innocuous Expectoration Of An Anterior C3 Loosened Screw—Case Report And Literature Review About A Benevolent Evolution With No Esophageal Injury, Gerson Reyes Rodriguez, José Alberto Israel Romero Rangel, Manuel Soto García, Manuel Rodriguez Garcia, Victor David Lopez Garcia, Iris Tatiana Montes González, José Antonio Soriano Sánchez

Archives of Neurosurgery

The anterior cervical discectomy and fusion (ACDF) technique is the gold-standard treatment for myeloradiculopathy. We present the case of a seventy-five years old female who came to revision because of worsening solids dysphagia, dry cough, and foreign body sensation in the past two weeks; we had practiced her an ACDF procedure four years ago. She denied presenting neurological deficit or neck pain. The physical examination was normal. Cephalic migration of the left C3 screw was evident on cervical plain and dynamic films and CT-Scan. She was admitted to the hospital for an upper gastrointestinal endoscopy that visualized retropharyngeal ulceration. Thirty …

Clinical Applications Of Direct Cortical Stimulation During Awake Craniotomies. Commentary On Passive Functional Mapping Using Infrared Thermography In Epilepsy Awake Surgery., Ramiro Antonio Perez De La Torre, Ramanathan Siddarth, Pérez Ramírez Pedro, Santiago Noé

Archives of Neurosurgery

As clinicians, we rely on various imaging methods to identify abnormal brain lesions. We can distinguish this myriad of neurological disorders by using imaging alone or together with either or both electrophysiological monitoring and direct cortical stimulation. This last alternative is the most frequently used approach to diagnosing brain lesions requiring awake craniotomies for adequate management. Awake craniotomies have become the standard of care for focal lesions, including vascular malformations like cavernous angiomas, intrinsic brain tumors, gliomas, vasculitic brain lesions, postinfectious brain lesions, brain metastasis, and also for epilepsy surgery. Surgery for epileptic patients requires multidisciplinary team interactions and a …

Adapting, Medha Reddy

Quill & Scope

No abstract provided.