Medicine and Health Sciences Commons^™

Students' Engagement Model In Online Learning Guided By School Counselor During Covid-19 Pandemic, Iis Solihah, Budi Astuti, Mussa Saidi Abubakari

Jurnal Kajian Bimbingan dan Konseling

The transformation into online learning during Covid 19 pandemic induces culture shock for students, teachers, and parents. Consequently, students present less participation in online learning. One of the stakeholders capable of improving students’ learning engagement is the school counselor. This study aims to examine secondary school students’ learning involved in the guidance and counseling online program. In this study, we employed a descriptive-quantitative research method, then collected data using a survey method and questionnaire. As many as 293 secondary school students from Java, Indonesia, participated in this study. Further, the obtained data were analyzed using SmartPLS 3. Our analysis results …

An Ethics Assessment Model For Teaching Global Health Program And Policy Implementation, Valerie Oji, Cheryl Knight, Renuka Mahatara, Vicki Oladoyin

Journal of Global Awareness

This mixed-method study surveyed and interviewed 60 High Income Country (HIC) US citizens/immigrants and Low-to-Middle-Income-Country (LMIC) citizens of African heritage on their perceptions of mental health services in African communities for implementation and research planning. In this study, ethics was a core emergent theme for global health initiatives and challenges, including political will for ethical change, community gatekeepers, level of government involvement, community-wide participation, public-private sector collaboration, health literacy and education, transparency, continuous monitoring, and consequences for ethical infractions. Based on our findings, we propose an active teaching and learning methodology of problem-based (PBL) and team-based learning (TBL) with multi-level …

The New Map: Energy, Climate, And The Clash Of Nations, Jay Nathan

Journal of Global Awareness

No abstract provided.

Pharmacokinetic Study Of Intranasal Dexamethasone And Methylprednisolone Compared With Intravenous Administration: Two Open-Label, Single-Dose, Two-Period, Two-Sequence, Cross-Over Study In Healthy Volunteers, Graciela Cárdenas, Raúl J. Bobes, Gladis Fragoso, Nicolas I. Pérez-Osorio, Marisela Hernández, Alejandro Espinosa, Agnes Fleury, José Flores, Juan Carlos Alvarenga, Juan Pedro Laclette

School of Medicine Publications

Dexamethasone (DXM) and methylprednisolone (MEP) are potent glucocorticoids used to control several inflammatory conditions. Evidence of delayed DXM reaching the central nervous system (CNS) as well as tachyphylaxis and systemic, undesirable side effects are the main limitations of peripheral delivery. Intranasal administration offers direct access to the brain as it bypasses the blood–brain barrier. The Mucosal Atomization Device is an optimal tool that can achieve rapid absorption into the CNS and the bloodstream across mucosal membranes. This study was designed to evaluate and compare the bioavailability of DXM and MEP after intranasal versus intravenous administration. Two open-label, balanced, randomized, two-treatment, …

Exploring Medical Marijuana Knowledge And Perceptions Among A Community-Based Sample, Lan'tejuana S. Cooper, Jullet Davis Weaver, Vanessa Crowther, Marisa Lewis

Florida Public Health Review

Exploring Medical Marijuana Knowledge and Perceptions among a Community-Based Sample

Abstract

Background: The increasing number of states legalizing marijuana suggests that a growing majority of adults now see marijuana as offering more benefits than risks. As use increases, the need to better understand user characteristics and the nature of their beliefs also increases. Purpose: This exploratory study investigates the knowledge and perceptions of medical marijuana among community-based individuals. We theorize that demographic characteristics, socioeconomic status, social network, health status, and knowledge about marijuana are associated with the number of conditions the person believes marijuana treats. Methods: The study utilizes a …

Research Highlights, Noopur Kumari, Babita Rani Kondle

Indian Journal of Research in Homoeopathy

Summary of the studies has been highlighted from Sep till Nov 2022.

Interventions To Treat And Prevent Postpartum Depression: A Protocol For Systematic Review Of The Literature And Parallel Network Meta-Analyses, David Thomas Monks, Basavaraj Ankalagi, Preet Mohinder Singh, Ebony Carter, Michelle Doering, Meg Guard, Shannon Lenze

2020-Current year OA Pubs

INTRODUCTION: Postpartum depression has costly consequences for the mother, baby, and society. Numerous pharmacological and non-pharmacological interventions are available for the prevention and treatment of postpartum depression. To date, no attempt has been made to synthesize the evidence from comparisons of interventions both within and across these categories.

METHODS: We will perform a systematic review of the literature and perform network meta-analysis of interventions to (a) prevent and (b) treat postpartum depression. This review will include studies of primiparous or multiparous women during pregnancy or within 12 months of delivery of their baby that assess either interventions initiated during pregnancy …

Cardiac Neural Crest And Cardiac Regeneration, Shannon Erhardt, Jun Wang

Faculty, Staff and Student Publications

Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that have the ability to migrate and differentiate into various cell populations throughout the embryo during embryogenesis. The heart is a muscular and complex organ whose primary function is to pump blood and nutrients throughout the body. Mammalian hearts, such as those of humans, lose their regenerative ability shortly after birth. However, a few vertebrate species, such as zebrafish, have the ability to self-repair/regenerate after cardiac damage. Recent research has discovered the potential functional ability and contribution of cardiac NCCs to cardiac regeneration through the use of various vertebrate …

Xatlas: Scalable Small Variant Calling Across Heterogeneous Next-Generation Sequencing Experiments, Jesse Farek, Daniel Hughes, William Salerno, Yiming Zhu, Aishwarya Pisupati, Adam Mansfield, Olga Krasheninina, Adam C English, Ginger Metcalf, Eric Boerwinkle, Donna M Muzny, Richard Gibbs, Ziad Khan, Fritz J Sedlazeck

Faculty, Staff and Students Publications

Background: The growing volume and heterogeneity of next-generation sequencing (NGS) data complicate the further optimization of identifying DNA variation, especially considering that curated high-confidence variant call sets frequently used to validate these methods are generally developed from the analysis of comparatively small and homogeneous sample sets.

Findings: We have developed xAtlas, a single-sample variant caller for single-nucleotide variants (SNVs) and small insertions and deletions (indels) in NGS data. xAtlas features rapid runtimes, support for CRAM and gVCF file formats, and retraining capabilities. xAtlas reports SNVs with 99.11% recall and 98.43% precision across a reference HG002 sample at 60× whole-genome coverage …

Construction Of Tudang Sipulung As A Group Counseling Strategy For Bugis Adolescents In The Perspective Of Kipas Counseling Model, Aswar Aswar, Edil Wijaya Nur, M. Amirullah, Fitriana Fitriana

Jurnal Kajian Bimbingan dan Konseling

The purpose of this article is to describe the existence of Tudang Sipulung for group guidance that used KIPAS Counseling for the Bugis Youth at Senior High School at Sidrap. This research used a qualitative approach with Triple Hermeneutic Analysis method. The data collection technique are Interview and literature studies as well as data validation which is achieved through data triangulation. The subjects of this study were four people, two people from public figure (culturalists) and two people from students (Bugis youth). The results showed that Tudang Sipulung is the ancestral heritage of the Sidrap’s Bugis Society which contains positive …

Real-Life Problems To Increase The Critical Analysis Thinking Among Novice Counselors In Humanistic Counseling Courses: Is It Effective?, Luthfita Cahya Irani, Suwarjo Suwarjo, Le Ngoc Ai Nhung

Jurnal Kajian Bimbingan dan Konseling

This study aims to determine the effectiveness of using real-life problems to improve novice counsellors' critical analytical thinking in humanistic counselling courses. The research method uses an experiment with a pretest-posttest control group design. The instrument used is a critical-analytical thinking scale. The research sample used a purposive sampling technique, which consisted of 84 students of the 2018 Guidance and Counseling UNY Study Program who took the Humanistic Counseling course. The samples were separated into experimental and control groups of 42 students. The pre-test and post-test data were analyzed using an independent sample t-test using SPSS Amos 25 software. The …

Human Character Based On Ki Ageng Suryomentaram Teachings And Its Implementation In Guidance And Counseling Services, Bakhrudin All Habsy, Nanda Alfan Kurniawan

Jurnal Kajian Bimbingan dan Konseling

The Indonesian nation as a large nation consisting of various religions, ethnicities, and cultures, of course, deserves to have the aspiration to have a basic human philosophy paradigm based on Indonesian culture based on dialogue between the soul sciences that live in Indonesian human cognition. This study aims to present the concept of basic human philosophy in the teachings of Ki Ageng Suryomentaram. The research method uses Gadamerian hermeneutics in a qualitative approach. The collected data is then analyzed using Parts and Whole analysis and then checked the validity of the data through the stages of credibility, transferability, dependability, and …

A Prospective Analysis Of Sources Of Referral To A Student Run Free Clinic In Camden, Nj, Samir Shah, Anjali Desai, Behjath Jafry

Cooper Rowan Medical Journal

Background: A center for learning and a haven for minority, marginalized, and medically indigent patients, the student run free clinic (SRFC) has emerged as a cornerstone of care at many academic medical centers (AMC). However, little is known regarding the demographics of patients who utilize SRFC and the manner in which they come to know of the free and quality care available at SRFC .

Methods: Participants were administered a survey wherein they were asked their ethnicity, how they came to know of the clinic, and how long they have remained a patient at the Cooper Rowan Clinic (CRC) – …

Establishment Of An In Vivo Streptozotocin-Induced Type 1 Diabetes Model Recapitulating Early Brain And Retinal Fibrosis, Kia Bourdot, Lucy Dawson, Igor Kuzin, Arturo Bravo Nuevo, Zeus Antonello

Cooper Rowan Medical Journal

INTRODUCTION: Diabetes has risen to one of the top American public health concerns. The hyperglycemic state of chronic diabetes leads to microvascular and macrovascular changes that predispose patients to delayed wound healing and organ fibrosis. The validation of models to specifically detect early, quantifiable fibrotic changes seen in the diabetic state is of fundamental importance for understanding the diabetic pathophysiology and exploring earlier management options. Here, we investigated if we could detect early signs of internal fibrosis in a streptozotocin (STZ) diabetic mouse model by quantifying α-SMA expression in various organs using flow cytometry.

METHODS: We used a low-dose STZ-induced …

Cerebellar High-Grade Glioma: A Translationally Oriented Review Of The Literature, Ashley L B Raghu, Jason A Chen, Pablo A Valdes, Walid Ibn Essayed, Elizabeth Claus, Omar Arnaout, Timothy R Smith, E Antonio Chiocca, Pier Paolo Peruzzi, Joshua D Bernstock

Faculty, Staff and Student Publications

World Health Organization (WHO) grade 4 gliomas of the cerebellum are rare entities whose understanding trails that of their supratentorial counterparts. Like supratentorial high-grade gliomas (sHGG), cerebellar high-grade gliomas (cHGG) preferentially affect males and prognosis is bleak; however, they are more common in a younger population. While current therapy for cerebellar and supratentorial HGG is the same, recent molecular analyses have identified features and subclasses of cerebellar tumors that may merit individualized targeting. One recent series of cHGG included the subclasses of (1) high-grade astrocytoma with piloid features (HGAP, ~31% of tumors); (2) H3K27M diffuse midline glioma (~8%); and (3) …

Safety And Microbiological Activity Of Phage Therapy In Persons With Cystic Fibrosis Colonized With Pseudomonas Aeruginosa: Study Protocol For A Phase 1b/2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial, Pranita D Tamma, Maria Souli, Michael Billard, Joseph Campbell, Douglas Conrad, Damon W Ellison, Beth Evans, Scott R Evans, Kerryl E Greenwood-Quaintance, Andrey A Filippov, Holly S Geres, Toshimitsu Hamasaki, Lauren Komarow, Mikeljon P Nikolich, Thomas P Lodise, Seema U Nayak, Carmelle Norice-Tra, Robin Patel, David Pride, Janie Russell, Daria Van Tyne, Henry F Chambers, Vance G Fowlerjr, Robert T Schooley, Antibacterial Resistance Leadership Group

Faculty, Staff and Student Publications

BACKGROUND: Bacteriophages (phages) are a promising anti-infective option for human disease. Major gaps remain in understanding their potential utility.

METHODS: This is a randomized, placebo-controlled, double-blind study of a single dose of intravenous phage in approximately 72 clinically stable adult cystic fibrosis volunteers recruited from up to 20 US sites with Pseudomonas aeruginosa airway colonization. The single dose of phage consists of a mixture of four anti-pseudomonal phages. Six sentinel participants will be sequentially enrolled with dose escalation of the phage mixture by one log

DISCUSSION: This trial will investigate the activity of phages in reducing P. aeruginosa colony counts …

Pertussis And Influenza Immunization: Perceived Attitude And Decision Of Postpartum Patients, Nutan B Hebballi, Tayler Parker, Elisa I Garcia, Dalya M Ferguson, Susan Lesser, Kuojen Tsao, Maryam Broussard, Susan H Wootton

Faculty, Staff and Student Publications

BACKGROUND: Vaccination of pregnant patients with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) and influenza vaccine during influenza season can reduce maternal and fetal morbidity and mortality; nevertheless, vaccination rates remain suboptimal in this patient population. To investigate the effect of a brief educational counseling session on maternal Tdap and influenza vaccination and determine factors influencing women's decision in regards to receiving Tdap and or influenza vaccine during their pregnancy.

METHODS: A face-to-face semi-structured cross-sectional survey was administered to postpartum patients on their anticipated day of discharge (June 11-August 21, 2018). A brief educational counseling session about maternal …

Clinical Significance Of Glycolytic Metabolic Activity In Hepatocellular Carcinoma, Joann Jung, Sowon Park, Yeonwoo Jang, Sung-Hwan Lee, Yun Seong Jeong, Sun Young Yim, Ju-Seog Lee

Faculty, Staff and Student Publications

High metabolic activity is a hallmark of cancers, including hepatocellular carcinoma (HCC). However, the molecular features of HCC with high metabolic activity contributing to clinical outcomes and the therapeutic implications of these characteristics are poorly understood. We aimed to define the features of HCC with high metabolic activity and uncover its association with response to current therapies. By integrating gene expression data from mouse liver tissues and tumor tissues from HCC patients (n = 1038), we uncovered three metabolically distinct HCC subtypes that differ in clinical outcomes and underlying molecular biology. The high metabolic subtype is characterized by poor …

An Rna Interference (Rnai) Toolkit And Its Utility For Functional Genetic Analysis Of Leishmania (Viannia), Lon-Fye Lye, Katherine L Owens, Soojin Jang, Joseph E Marcus, Erin A Brettmann, Stephen M Beverley

2020-Current year OA Pubs

RNA interference (RNAi) is a powerful tool whose efficacy against a broad range of targets enables functional genetic tests individually or systematically. However, the RNAi pathway has been lost in evolution by a variety of eukaryotes including most Leishmania sp. RNAi was retained in species of the

Socioecological Predictors Of Breastfeeding Practices In Rural Eastern Ethiopia, Marina Magalhães, Amanda Ojeda, Karah Mechlowitz, Kaitlin Brittain, Jenna Daniel, Kedir Teji Roba, Jemal Yousuf Hassen, Mark J Manary, Wondwossen A Gebreyes, Arie H Havelaar, Sarah L Mckune

2020-Current year OA Pubs

BACKGROUND: Estimates by the World Health Organization indicate that over 800,000 global neonatal deaths each year are attributed to deviations from recommended best practices in infant feeding. Identifying factors promoting ideal breastfeeding practices may facilitate efforts to decrease neonatal and infant death rates and progress towards achieving the Sustainable Development Goals set for 2030. Though numerous studies have identified the benefits of breastfeeding in reducing the risk of childhood undernutrition, infection and illness, and mortality in low- and middle-income countries, no studies have explored predictors of breastfeeding practices in rural eastern Ethiopia, where undernutrition is widespread. The aim of this …

The Maternal And Infant Environmental Health Riskscape Study Of Perinatal Disparities In Greater Houston: Rationale, Study Design And Participant Profiles, R Jeanne Ruiz, Kristyn Grimes, Elizabeth Spurlock, Angela Stotts, Thomas F Northrup, Yolanda Villarreal, Robert Suchting, Melissa Cernuch, Liza Rivera, Raymond P Stowe, Rita H Pickler

Faculty, Staff and Student Publications

BACKGROUND: Pregnant Mexican Americans (hereafter called Latinas) and Black/African American women are at increased risk for psychological distress, contributing to preterm birth and low birthweight; acculturative stress combined with perceived stress elevates depressive symptoms in Latinas. Based on our prior research using a psychoneuroimmunology framework, we identified psychological and neuroendocrine risk factors as predictors of preterm birth in Latina women that are also identified as risk factors for Black/African American women.

METHODS/DESIGN: In this prospective, randomized controlled trial with parallel group design we will explore psychosocial, neuroendocrine, and birth outcome effects of the Mastery Lifestyle Intervention (MLI). The MLI is …

Ai In The Hands Of Imperfect Users, Kristin M Kostick-Quenet, Sara Gerke

Center for Medical Ethics and Health Policy Staff Publications

As the use of artificial intelligence and machine learning (AI/ML) continues to expand in healthcare, much attention has been given to mitigating bias in algorithms to ensure they are employed fairly and transparently. Less attention has fallen to addressing potential bias among AI/ML's human users or factors that influence user reliance. We argue for a systematic approach to identifying the existence and impacts of user biases while using AI/ML tools and call for the development of embedded interface design features, drawing on insights from decision science and behavioral economics, to nudge users towards more critical and reflective decision making using …

Pneumococcal Vaccine Guidance 2022, Bona Shin, Michael Do, Elaina Lioudis

Transformative Medicine

PCV15 and PCV20 received FDA approval in 2021. This article provides an overview of all pneumococcal vaccines - PPSV23, PCV13, PCV15, and PCV20 and their place in therapy. It provides a summary of pneumococcal disease burden in the U.S., vaccine spectrum of activity, indications, adult/pediatric dosing schedules, efficacy, and common adverse drug reactions.

“I Have A Lot Of Pvcs And I Need To See A Cardiologist”, Ravi Choxi, Arun Kundra

Transformative Medicine

No abstract provided.

Forest Therapy For Anxiety, Fiteh Yelekal, Nipa Doshi

Transformative Medicine

No abstract provided.

Multidisciplinary Retreatment Of Skeletal Class Ii Malocclusion With Obstructive Sleep Apnea And Multiple Prosthesis, Si-Rong Chen, Cheng-Hui Lin, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Obstructive sleep apnea (OSA) is a common sleep disorder syndrome, especially in the middle-aged, obese men population. Patients suffer from an interrupted sleep at night, which could be life-threatening. Treatment alternatives include continuous positive airway pressure, mandible advanced device, nasal surgery and maxillo-mandibular advancement surgery. This article presented a patient who came with chief complaints of lower jaw retrusion, poor sleep quality, unsatisfactory occlusion and old prosthesis. The patient had declined the surgical-orthodontics in 12 years ago, and went for another camouflage orthodontic treatment with extraction of teeth and multiple prosthesis. He presented with skeletal Class II with retrognathic mandible …

Camouflage Treatment Of Skeletal Anterior Open Bite With Tongue Training, Cheng-Han Sie, Wen-Ken Tai, Chih-Chen Chou, Po-Yu Yang, Jung-Chun Yeh, Chun-Te Ho, Chia-Tze Kao

Taiwanese Journal of Orthodontics

The aim of this case report was to present an adult patient who suffered from poor occlusal function and poor aesthetic appearance due to skeletal anterior open bite. After orthodontic treatment, she was satisfied with improvements of mastication and esthetics. A case of 20-year-old female with skeletal Class II jaw relationship, mandible retrognathism and anterior open bite without signs and symptoms of temporomandibular disorder. Intraoral examination showed premature contact over bilateral posterior teeth and the forward resting position of tongue. Our treatment plan was orthodontic camouflage with extraction of all first premolars and tongue training. As forward resting position of …

Quality Of Life Changes In Taiwanese Patients With Dentofacial Deformities Undergoing Orthognathic Surgery, Jing Hao Ng, I-Chen Lee, Becky Chiang-Lin Liu, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Objectives: The evaluation of orthognathic surgery (OgS) is shifting towards a coherent approach for patient care that balances objective clinician-defined measures with patient-centred outcome assessments, including health-related quality of life (QoL). This aim of this study adds to the pool of literature in East Asian subjects by studying the longitudinal QoL changes in Taiwanese patients with dentofacial deformities (DFD) undergoing OgS, using two standardized questionnaires at three different treatment stages. Materials and Methods: This prospective cohort study comprised 113 consecutive Taiwanese OgS patients who underwent surgical-orthodontic treatment between 2015 and 2018. The subjects completed SF-36 and OHIP-14 standardized questionnaires with …

Comparison Of Bone Thickness In Infrazygomatic Crest Area At Various Miniscrew Insertion Angles: A Cone-Beam Computed Tomographic Study, Rajju Dangal, Rabindra Man Shrestha, Jyoti Dhakal, Sujita Shrestha, Alka Gupta, Shreya Shah

Taiwanese Journal of Orthodontics

Introduction: The infrazygomatic crest (IZC) is an alternative site for miniscrew anchorage. It is important to analyze the anatomy of the region during preoperative planning to minimize the risk of unwanted tooth movement and injury to the vital structures. The literatures on the clinical application of miniscrew in IZC is scarce. Objective: To determine bone thickness, height and angle of insertion of miniscrew in the IZC region. Materials and methods: This cross-sectional observational comparative study included 44 patients above18 years. IZC bone thickness and height of miniscrew insertion were measured on cone-beam computed tomographic (CBCT) records. Student t-test was done …

Cephalometric Analysis: History And Clinical Application, Ib Leth Nielsen

Taiwanese Journal of Orthodontics

When roentgen cephalometry was first introduced to the orthodontic profession in 1931 by Broadbent in the USA and Hofrath in Germany it was a major milestone in terms of new diagnostic tools available to orthodontists. Until that time only clinical observation and study casts of the patients had been available to the clinician but now a more in depth understanding of the facial makeup became possible. This meant that each patient’s malocclusion could now be related to their facial skeletal and dental morphology. The dentoalveolar components could now be studied in detail and better treatment plans could be developed that …