Medicine and Health Sciences Commons^™

Brain Charts For The Human Lifespan, R. A. I. Bethlehem, J. Seidlitz, S. R. White, J. W. Vogel, K. Anderson, C. Adamson, S. Adler, G. S. Alexopoulos, E. Anagnostou, John Blangero

School of Medicine Publications

Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual differences in neuroimaging metrics over time, in contrast to growth charts for anthropometric traits such as height and weight1. Here we assemble an interactive open resource to benchmark brain morphology derived from any current or future sample of MRI data (http://www.brainchart.io/). With the goal of basing these reference charts on the largest and most inclusive dataset available, acknowledging limitations due to known biases of MRI studies …

A Pilot Study To Examine The Effects Of Beta-Alanine And Sodium Citrate (Carnorushtm, Olimp®) Supplementation On Climbing-Specific Performance, Krzysztof Sas-Nowosielski, Piotr Kaczka

Baltic Journal of Health and Physical Activity

Introduction. Competitive and rock climbers primarily rely on anaerobic energy metabolism, and acidosis may limit their performance. It is supposed that supplements that improve buffering capacities of the body, like β-alanine (BA) and sodium bicarbonate/citrate (SB/SC), may be useful in this sport. The aim of the study was to explore the efficacy of co-supplementation of BA and SC on climbing performance. Material and methods. 13 climbers (age 40.2 ±7.9 years, height 175.4 ±8.4 cm, body mass 68.6 ±13.9 kg, UIAA metric 9.2 ±0.8) were randomly assigned to the supplement (SG; n = 7) or control group (CG: n = 6). …

Communication Is Key, Stephanie Munsch, Bailey Ellingsworth

Scholars Week

Abstract

This paper is an evidence based look at the efficacy of ventilation communication in the intensive care unit (ICU) and the resources that we found to be useful in expanding said communication. This topic has become more prevalent today due to COVID-19 and the rising numbers of ICU admissions and ventilator use. We looked at various studies that found that patients on ventilators who lacked good communication with their nurses had negative mental and physical effects. Examples of this include increased rates of anxiety, depression, and post traumatic stress disorder among ICU survivors. The evidence also found that effective …

Decreasing Alarm Fatigue Through Alarm Management Training, Leah Davis, Brittany Fleming

Scholars Week

Alarm fatigue is a notable problem in the hospital setting. Alarm fatigue can decrease nurse response time and desensitize nurses to alarms. When this occurs, patient outcomes begin to be negatively affected. To combat this, we researched multiple articles on alarm fatigue and alarm management programs. These programs would be implemented and nurses would learn how to troubleshoot alarm equipment, how to recognize alarm fatigue, how to prevent alarm fatigue, and many more. Based on research articles, alarm management programs decrease alarm fatigue in nurses and the amount of alarms.

Implementing Hourly Rounding, Kalyn Grice, Emma Durham

Scholars Week

It has been long known that nurses can be stretched thin during their 12 hour shifts. Whether they are running around passing medications, completing orders, or performing nursing interventions the world of nursing is always go, go, go. With this mindset and culture some patients who require less tasks and care may be overlooked and not seen for a few hours during a shift. This can lead to negative patient outcomes and safety problems. Throughout the day patient’s require assistance to meet many different needs, many of them being activities of daily living, like using the restroom, changing positions, brushing …

Improving Patient Medication Teaching With A “Meds-To-Beds” Program, Grace Phelps, Shanna Blocker

Scholars Week

Medication education is a vital part of a healthcare provider’s job. Nurses specifically often must take on the main role in medication education in collaboration with physicians and pharmacists. The current medication education at a certain hospital involves discharging patients with a list of medications, dosages, and instructions. The policy also includes the use of layman terms in discussion and handing the patient a sheet with the date/time of last administration by the nurse. Before discussing a change in policy, it is important to first clarify who must take on the responsibility of medication education . This is within the …

Too Loud: A Project For Sound Reduction In The Neonatal Intensive Care Unit, Peyton Cadwell, Amy Krazl

Scholars Week

Sound levels in any intensive care unit environment are significantly higher than the recommended volume. The neonatal intensive care unit (NICU) is included in this aggregate that frequently exceeds advised levels. There are consequences associated with increased sound, such as slower language development and behavior issues. Not only are babies subjected to physiological effects, but there is potential for psychological detriment as well, such as behavioral issues (Bremmer, 2003). Many solutions for this issue have been proposed, including lowering phone volumes, putting rubber shoes on furniture and switching audio alarms to visual alarms. One specific intervention that may reduce the …

Iv Infection Control, Coleman White, Hannah Oswalt

Scholars Week

Infection is one of the most discussed topics in the nursing world, and one topic that is commonly overlooked is IV tubing related to infection. The current rules on CCU/PCU include labeling the tubing, changing the tubing every 72 hours, and cleaning the site with an alcohol swab before injecting medications. While these rules in place are evidenced based, and work properly, there is more research that has been conducted stating better practice to control infection related to IV tubing. Through utilization of theoretical framework along with several quasi-experimental research, we have evaluated infection control effectiveness through “Scrub the Hub” …

How To Control Healthcare Associated Infection, Yeojin Son, Jungyoon Hur

Scholars Week

Healthcare-Associated Infections (HAI) are infections patients acquire while receiving care in hospital. The main reasons of occurring the infections are insufficient knowledge about infection control and decreased compliance with rules by hospital protocol. The purpose of this evidence-based presentation is to exemplify how to control HAI via motivating healthcare workers to comply with infection control policy.

Prevention Of Medical Device Related Pressure Injuries (Mdpris), Mauritzio Ramirez, Audrey M. Fulkerson, Mason L. Chandler

Scholars Week

Throughout our clinical rotations, we noticed many patients who had developed pressure ulcers caused by medical devices, which are often referred to as MDRPIs. We acknowledged this as a problem and decided to look into it further. We reviewed various articles to find the best practice when it comes to preventing/minimizing these injuries. We analyzed a meta-synthesis, a qualitative study, and an experimental study and used that as our research on the topic. After reviewing these articles, we will present our findings to a local hospital to make recommendations on how they can better prevent/minimize MDRPIs. In conclusion, MDRPIs are …

The Benefits Of Bedside Shift Report, Sarah Frank, Jordan Reed, Jordan Higgins

Scholars Week

The purpose of this research is to investigate the impact of bedside shift report in the health care setting. This research will focus on an inpatient department, which is a 25-bed acute care unit with 4 special care beds. This department currently utilizes the SBAR method. However, this can improve when used in conjunction with bedside shift reports. The use of bedside shift report will improve communication and nurse-patient relationships, provide more patient privacy, and decrease time spent giving report. The use of bedside report may require a related intervention of patient teaching, so that the patient understands the purpose …

Benefits Of Increasing Patient Engagement In Plan Of Care, Madison Gillentine, Stephanie Phelps

Scholars Week

This presentation’s focus is implementing ways to engage patients in their own plan of care during hospitalization. Patient’s presenting their needs early on during a hospital stay has been shown to improve nurse-patient communication and overall engagement. When a patient has felt that his or her specific needs have been made aware to the nursing staff, one feels more like an individual rather than a bed number. The patient will become a more active member in his or her care which leads to better outcomes and satisfaction. The more comfortable and open a patient is with the nurse about his …

Effective Communication In Dementia Patients, Morgan Loveless, Callie Hardesty

Scholars Week

Effective Communication with Dementia Patients - Abstract

Throughout every nurse’s career, one will have the experience of working with those with dementia. Patients who suffer with dementia require different approaches to communication and may have difficult interactions with healthcare workers. A barrier many nurses continue to endure is poor communication and relationships with dementia patients. Many nurses work at a very quick and stressful pace, putting a strain on many nurses’ relationships with dementia patients. Ineffective communication may lower the quality of care dementia patients receive as nurses may lack the extra time needed to effectively communicate. This can lead …

Reducing Pediatric Procedural Pain Using Virtual Reality, Emily Davis, Carmen Bandy

Scholars Week

Above all else, children require stability in their lives in order to develop a healthy perspective of the world. Feelings of instability can come from something as small as a change in schools. In the practice of pediatric medicine it is especially important to avoid these feelings of instability, which can lead children to develop healthcare-anxiety. Healthcare settings can be exceptionally emotionally taxing to children, because the children have a complete lack of control over their environment. This lack of control combined with fear and potentially pain can be incredibly distressing. While it is easy to disregard a child’s anxiety …

Stress Management In Nursing To Prevent Burnout And Employee Retention, Megan Mayo, Lauren R. Barto, Megan B. Trout

Scholars Week

This project was based on the fact that there is a severe nursing shortage happening in the United States. On average, nurses can have four to eight patients at one time which makes a twelve hour shift almost unbearable due to the stress of keeping all of the patients alive and satisfied with the care they are receiving. During the pandemic, staffing shortages have become one of the main issues faced by healthcare workers across the nation. Due to the staffing shortages and COVID-19 precautions, nurses have not only been taking on more patients but also have increased their workload …

Additional Booster Vaccinations Are Available, April 5, 2022, University Of Northern Iowa

UNI Response to COVID-19

Announces the availability of a second booster shot for individuals 50 years of age or older at the Student Health Clinic in accordance with the CDC guidelines of April 2022.

Youth Mental Health In The Mountain West, Kristian Thymianos, Olivia K. Cheche, Kelliann Beavers, Katie M. Gilbertson, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet explores youth mental health metrics of Mountain West states from the Hopeful Futures Campaign’s 2022 report, America’s School Mental Health Report Card. This study provides state snapshots on school mental health policies and workforce availability for all 50 states and the District of Columbia. The Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah are considered here.

Coronavirus Update 4-5-22, The Coronavirus Planning Team

University Briefings & Virtual Events

Based on current numbers and trends and in accordance with CDC guidance, we will recommend vaccination, but not require it, for the fall. Vaccination has been one component of our strategy, along with testing, tracing, isolation, quarantine, masking, hygiene and social distancing. We will continue to follow the way the virus evolves and listen to the advice of state and local health officials, and we will let you know over the summer as decisions are made on our testing, isolation and other strategies for the fall.

2022-04-05_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

Protein Tyrosine Phosphatase Receptor Δ Serves As The Orexigenic Asprosin Receptor, Ila Mishra, Wei Rose Xie, Juan C Bournat, Yang He, Chunmei Wang, Elizabeth Sabath Silva, Hailan Liu, Zhiqiang Ku, Yinghua Chen, Bernadette O Erokwu, Peilin Jia, Zhongming Zhao, Zhiqiang An, Chris A Flask, Yanlin He, Yong Xu, Atul R Chopra

Faculty, Staff and Student Publications

Asprosin is a fasting-induced glucogenic and centrally acting orexigenic hormone. The olfactory receptor Olfr734 is known to be the hepatic receptor for asprosin that mediates its effects on glucose production, but the receptor for asprosin's orexigenic function has been unclear. Here, we have identified protein tyrosine phosphatase receptor δ (Ptprd) as the orexigenic receptor for asprosin. Asprosin functions as a high-affinity Ptprd ligand in hypothalamic AgRP neurons, regulating the activity of this circuit in a cell-autonomous manner. Genetic ablation of Ptprd results in a strong loss of appetite, leanness, and an inability to respond to the orexigenic effects of asprosin. …

Applying Self-Compassion And Stress Management Techniques To Increase Healthy Behaviors Among Women At The New Beginnings Center, Payton Knupp

OTD Capstone Projects

The New Beginnings Center is a nonprofit organization that serves as an empowerment program for women from disadvantaged backgrounds in the Nashville area. Current curriculum includes a 12-week program focused on nutrition, exercise, and positive lifestyle changes that provide a holistic approach to long-term behavior change and a lasting support system. The objective for this project was to provide updated programming based on current research and relevant topics for the population, utilizing the cognitive behavioral frame of reference to facilitate behavior change, reframing negative and distorted thinking into healthy and productive habits. The subjects of the two workshops focused on …

Trigonella Foenum-Graecum Methanolic Extract On Isolated Smooth Muscles And Acetylcholinesterase Enzyme: An In Vitro And Mechanistic In Silico Investigation, Muhammad Nabeel Ghayur, Mohnad Abdalla, Asaad Khalid, Saeed Ahmad, Anwar Gilani

Department of Biological & Biomedical Sciences

Results: When tested on the baseline of isolated tissues, Tfg.Cr was devoid of any activity (stimulant or relaxant) till 10 mg/ml. This is an interesting finding, keeping in mind that the fenugreek seeds are used to alleviate constipation and diarrhoea. When Tfg.Cr was tried for any potential AChE inhibitory activity, it did show an inhibitory effect in increasing concentrations (47-380 μg/ml). This inhibitory effect was comparable to the effect produced by a standard AChE inhibitor physostigmine. One of the known fenugreek constituents, diosgenin, was also tested, and it also showed an AChE inhibitory effect in a concentration-dependent manner (11-190 …

Coaching For Independent Living Skills In Adults With Intellectual And Developmental Disabilities At Friends Life Community, Ashley G. Raby

OTD Capstone Projects

Friends Life Community is an organization that serves individuals with intellectual and developmental disabilities (IDD) in Nashville, TN. They provide a day program, drama therapy, social clubs, career coaching, and life coaching. The life coaching program is an individualized service provided to clients who are striving to become more independent in life skills. This project focused on creating resources and assessments to aid in the coaching process. Resources were created in the following categories: activities, cleaning, hygiene and routines, nutrition and exercise, and budgeting.

Interpersonal Communication In Eye Care: An Analysis Of Potential Impacts On Cataract Surgery Candidates’ Expectations And Behaviors, Amy Hellem, Sara Labelle, Cynthia Matossian, Paul Karpecki

Communication Faculty Articles and Research

Purpose: To identify cataract surgery candidates’ knowledge, beliefs, desires and emotions as they relate to cataract surgery generally as well as to their behavioral intent to adhere to a doctor-recommended pre-surgical ocular surface prep routine designed to improve refractive outcomes and prevent surgical complications.

Methods: This national, noninterventional, cross-sectional, mixed methods survey included 278 US adults ages 65 and older with no history of cataract surgery in either eye.

Results: Only 20% of participants said they want to have cataract surgery, and even fewer (8%) said they wish they could have cataract surgery right away. Fear was the predominant emotion …

Belmont University Covid Surveillance And Containment: An Evaluation Of Program Effectiveness, Morgan A. Lambrecht

DNP Projects

In the early days of the Coronavirus (COVID) pandemic, members of university communities faced elevated risk of contracting COVID because they live and work in congregate settings, with shared living and dining arrangements. By the Fall 2020 semester, with limited information regarding the transmission of COVID, a quick, but comprehensive strategy was needed to allow students to return to university campuses, while maintaining a safe environment for students, faculty, and staff. The purpose of this project was to determine the effectiveness of the COVID surveillance and containment measures implemented in the 2020/2021 academic year for the residential campus community at …

Covid-19 Vaccine Uptake Among College Students, Erin Hoening, Elizabeth Morse, David Phillippi, Krystal Huesmann

DNP Projects

Background: Public health strategies to improve COVID-19 vaccine uptake among college students living in residential communities varied, some universities opted to mandate COVID-19 vaccines while other universities opted to promote and influence the choice for vaccination.

Purpose: This descriptive, cross-sectional study examined the voluntary uptake of COVID-19 vaccines among residential students on a college campus in the southeastern U.S. that elected an evidence-driven health promotion strategy that included strong health promotion messaging coupled with coordinated efforts to make the vaccine accessible and appealing to students on campus.

Methods: Analysis of vaccine uptake was derived from campus electronic health records during …

Association Between Non-Tea Flavonoid Intake And Risk Of Type 2 Diabetes: The Australian Diabetes, Obesity And Lifestyle Study, Mary D. Adu, Catherine P. Bondonno, Benjamin H. Parmenter, Marc Sim, Raymond J. Davey, Kevin Murray, Simone Radavelli Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno

Research outputs 2022 to 2026

Studies examining the association between flavonoid intake and measures of insulin resistance and β-cell dysfunction, as markers of type 2 diabetes (T2DM) across the adult lifespan, may provide insights into how flavonoids influence T2DM risk. This study examined the cross-sectional associations between flavonoid intakes, from dietary sources other than tea, and biomarkers of glucose tolerance and insulin sensitivity in adults aged 25 years and older participating in the Australian diabetes, obesity and lifestyle (AusDiab) study. Additionally, longitudinal associations between non-tea flavonoid intakes and incident T2DM over 12 years were explored. Eligible participants (n = 7675) had no previous history of …

Safe Consumption Sites Are Critical To Reducing Drug Overdoses, Alexandra Punch

Population Health Research Brief Series

In 2021, over 100,000 people died from drug overdoses in the United States, resulting in the country’s deadliest year on record for drug overdoses. Much of the increase in drug overdose rates over the past several years has been due to fentanyl, a highly potent manufactured opioid with a high risk of overdose. Coupled with the risk of transmission of blood-borne diseases, such as HIV and Hepatitis C from sharing drug paraphernalia, individuals who use drugs face numerous challenges in safely consuming drugs. This issue brief advocates for the implementation of safe consumption sites across the U.S. and calls for …

Chronic Alcohol Exposure Induces Hepatocyte Damage By Inducing Oxidative Stress, Satb2 And Stem Cell-Like Characteristics, And Activating Lipogenesis, Wei Yu, Yiming Ma, Sushant K. Shrivastava, Rakesh K. Srivastava, Sharmila Shankar

School of Medicine Faculty Publications

Alcohol is a risk factor for hepatocellular carcinoma (HCC). However, the molecular mechanism by which chronic alcohol consumption contributes to HCC is not well understood. The purpose of the study was to demonstrate the effects of chronic ethanol exposure on the damage of human normal hepatocytes. Our data showed that chronic exposure of hepatocytes with ethanol induced changes similar to transformed hepatocytes that is, exhibited colonies and anchorage-independent growth. These damaged hepatocytes contained high levels of reactive oxygen species (ROS) and showed induction of the SATB2 gene. Furthermore, damaged hepatocytes gained the phenotypes of CSCs which expressed stem cell markers …

Promoting Community Accessibility Through Advocacy And Networking With The Ability App, Chloe C. Moore

OTD Capstone Projects

Promoting Community Accessibility Through Advocacy and
Networking with The Ability App Networking with The Ability App