Medicine and Health Sciences Commons^™

Cancer Survivors’ Participation In Meaningful Life Activities, A Mixed Methods Approach, Allison Jean L'Hotta

Arts & Sciences Graduate Student Theses and Dissertations

A new cancer diagnosis dramatically impacts an individual’s daily life. While data describing cancer-related symptoms (e.g. fatigue) and impairments (e.g. weakness) are abundant, there remains limited data detailing the impact of cancer on survivors’ daily life participation. Advancement in participation research is challenged by the lack of a universally accepted definition of participation and a standard approach to measurement. Previous research evaluating participation among cancer survivors is limited by small sample sizes, cross-sectional data including only a single disease group, and assessing participation exclusively among individuals who have completed active cancer treatment. The purpose of the presented dissertation was to …

Survival Percentage And Outgrowth Collection Kit (Spock) Development And Usage To Analyze Targets Of The Transcription Factor Gcn4 For Their Impact On Chronological Lifespan In The Model Organism S. Cerevisiae, Daniel Paul Felker

Biomedical Sciences ETDs

Plate reader-based methods for high-throughput measurement of growth rate, cellular survival, and chronological lifespan are a compelling addition to the already powerful toolbox of budding yeast Saccharomyces cerevisiae genetics. These methods have overcome many of the limits of traditional yeast biology techniques, but also present a new bottleneck at the point of data-analysis. Herein, we describe SPOCK (Survival Percentage and Outgrowth Collection Kit), an R-based package for the analysis of data created by high-throughput plate reader based methods. This package allows for the determination of chronological lifespan, cellular growth rate, and survival in an efficient, robust, and reproducible fashion. To …

Systematic Expression Profiling Of Dpr And Dip Genes Reveals Cell Surface Codes In Drosophila Larval Motor And Sensory Neurons, Yupu Wang, Meike Lobb-Rabe, James Ashley, Purujit Chatterjee, Veera Anand, Hugo J Bellen, Oguz Kanca, Robert A Carrillo

Faculty, Staff and Students Publications

In complex nervous systems, neurons must identify their correct partners to form synaptic connections. The prevailing model to ensure correct recognition posits that cell-surface proteins (CSPs) in individual neurons act as identification tags. Thus, knowing what cells express which CSPs would provide insights into neural development, synaptic connectivity, and nervous system evolution. Here, we investigated expression of Dpr and DIP genes, two CSP subfamilies belonging to the immunoglobulin superfamily, in Drosophila larval motor neurons (MNs), muscles, glia and sensory neurons (SNs) using a collection of GAL4 driver lines. We found that Dpr genes are more broadly expressed than DIP genes …

Systematic Approach Based On The Use Of Compensatory Exercises With An Impact On The Indicators Of Motor Qualities, Doniyor Bahodirovich Yadgarov

Eurasian Journal of Sport Science

Aim: To substantiate that the use of compensatory exercises with a selective effect on the declining indicators of motor qualities of inactive muscle groups can increase the level and ensure a positive trend in the indicators of physical fitness of schoolchildren of grades 3-4.

Methods: To achieve this, the following research methods were used:

1) study of special literature, individual diaries of physical education teachers.

2) questionnaire,

3) anthropometric measurements,

4) the method of control exercises,

5) ascertaining experiment.

6) pedagogical experiment,

7) mathematical statistics.

Results: To improve the quality of physical education lessons, it is recommended and implemented: 1. …

Provider Education On Non-Pharmacologic Treatment Of Osteoarthritis, Brandi P. Whetzell

Doctor of Nursing Practice Scholarly Project

Osteoarthritis is an arthritic condition of the joints commonly found in the elderly population. This condition occurs as intra-articular cartilage wears down over time. Most patients present with joint pain. The pain that occurs from joint pain often impedes physical activity, which can ultimately increase pain levels. There are several treatments for osteoarthritis, however, there is no cure. Providers often prescribe non-steroidal anti-inflammatories and other oral analgesics for pain management. Because osteoarthritis typically occurs in the elderly population, adding medications to what often is a long list of medications can cause issues such as drug interactions and medication toxicities. Other …

Cultural Beliefs About Healthy And Unhealthy Weight In Children 2 To 11 Years Of Age Among Parents Of Mexican Heritage, Nathalie Confiac

Electronic Theses and Dissertations

Introduction: Despite multisectoral preventive interventions, the obesity prevalence among children of Mexican heritage remains the highest of all ethnic groups in the US. Methodology: Guided by Leininger’s Culture Care Diversity and Universality Theory, this study explored the culture care beliefs and practices of Mexican heritage parents about healthy and unhealthy weight in children 2-11 years of age using the ethnonursing research method. Eight key and 17 general informants were interviewed, and the four phases of ethnonursing data analysis guided analysis. Results: Twenty-six categories were identified which led to seven culture care patterns revealing four themes. Informants shared the …

Unified Philosophy For Music Therapy: Solving The Identity Crisis Through Interdisciplinary Analysis, Janice Lindstrom

Graduate Liberal Studies Theses and Dissertations

The purpose of this dissertation was to investigate the feasibility of a unifying philosophy for music therapy and to offer an identity for the music therapy profession that is appropriate for the various ways in which music therapy is practiced throughout the world. A systematic review of published music therapy approaches informed this investigation. The central research questions for this dissertation were: (a) Is it possible to articulate a unifying philosophy of music therapy that is inclusive of the diverse ways music therapy is currently practiced; and if so, (b) What might be that resultant integrated philosophy of music therapy? …

Intercorrelations Between Essentialist Beliefs And The Social Identities Of Religion, Political Affiliation, And Nationality, Truman Deree

Senior Honors Projects, 2020-current

In this study, I investigated the relationships between political identity, religious identity, and national identity, as well as related attitudes about essentialism. I hypothesized that having essentialist attitudes about one identity group will correlate with having essentialist attitudes about other identities. I also predicted that the more important an identity is to one’s sense of self, the more likely they will be to hold essentialist attitudes about that identity. Finally, I predicted that having a Republican identity positively correlates with essentialist views of one’s national identity. In this paper, I discuss the theoretical basis, as well as the method, sampling …

Dynamic Measures Of Referential Communication Reveal Hidden Pragmatic Strengths For Adolescents With Autism Spectrum Disorder, Mariana Schreuders

Senior Honors Projects, 2020-current

The ability to communicate effectively and efficiently while maintaining mutual understanding is a fundamental aspect of human-to-human interaction. Studies have shown that individuals with autism spectrum disorder (ASD) face challenges in areas of social communication skills, such as aspects of referential communication; or the ability to refer to things in such a way that a listener will know what the speaker is describing. The current study used data from a preexisting Barrier study to compare the referential communication abilities of school-aged children with ASD to those of neurotypical children (NT). Referential communication was observed during a barrier task, where participants …

Paving The Way To Understanding Female-Headed Households: Variation In Household Composition Across 103 Low-And Middle-Income Countries, Ghada E. Saad, Hala Ghattas Ph.D., Andrea Wendt, Franciele Hellwig, Jocelyn Dejong, Ties Boerma, Cesar Victora, Aluisio J.D. Barros

Faculty Publications

Background

Female-headed households (FHHs) are regarded as disadvantaged. There are multiple social trajectories that can lead to women heading households. It is important to distinguish between these trajectories, as well as societal norms and contextual factors, to understand how and when are FHHs represented as a dimension of gender inequity. Our analysis defines and describes a typology of 16 FHH types (FHH16) based on demographic characteristics.

Methods

This cross-sectional study used national Demographic Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS) in 103 low- and middle-income countries (LMICs) to identify a typology of FHHs based on the family composition …

Genetic Origins Of Polycystic Ovarian Syndrome (Pcos): An Analysis Of The Genetic Correlation Between Pcos And Insulin Receptor Mutations, Lauren Henry

Undergraduate Theses

Polycystic Ovarian Syndrome (PCOS) remains an extremely common, yet understudied syndrome experienced by 6-12% of females of reproductive age. Not only does it cause painful side effects manifesting both physically and mentally, but it also poses a threat to the fertility of those affected. For this reason, a more in-depth analysis to better understand how to detect this condition early and prevent fertility complications later is certainly warranted. PCOS is suspected to be primarily genetic due to correlations among immediate female family members. Based on previous research, a good starting point for analysis is the INSR gene. Various mutations within …

Exploring Moral Permissibility Of Nurse Participation In Limited Resuscitation, Felicia Stokes

Electronic Theses and Dissertations

This dissertation offers a novel approach to support nurses when they face conflict between clinicians and families or alternate decision-makers over potentially inappropriate end-of-life goals of care. This dissertation will provide a normative analysis of the moral permissibility of limited resuscitation, with arguments supported by analyses of families’ and nurses’ perspectives and actions in the EoL decision-making process. Limited resuscitation is a cardiopulmonary resuscitation effort where full pharmacologic and mechanical intervention is not used, or the length of the resuscitative effort is shortened. It is typically associated with deception because it is performed without the knowledge of patients and families. …

Long-Term Health Outcomes For Adult Women Who Experienced Sexual Assault, Jodie Flynn

Electronic Theses and Dissertations

The purpose of this study is to understand the impact of sexual assault pre- and post-sexual assault on health, health care experience, and health-related quality of life in adult women. Research identifying quality of life as a health outcome post-sexual assault is limited. No long-term studies to evaluate differences in health-related quality of life pre-and post-sexual assault have been conducted. In addition, only a few studies have investigated mental health changes over time. An exploration into self-perceived general health pre-and post-sexual assault and overall current quality of life needs to be conducted to determine improvements in health care services for …

Evaluation Of An Educational Presentation On Improving Nursing Students’ Knowledge About Medication Reconciliation, My Trinh

Doctor of Nursing Practice Scholarly Project

Medication reconciliation is the process of comparing a patient’s medications that they are currently taking and comparing it with newly ordered medications or comparing the list to another source of information. It is completed to avoid and reduce the risk for potential adverse drug events, medication discrepancies, and improve communication between transition of care settings. Although people acknowledge and perceive the value of medication reconciliation as an important process in reducing medication errors and patient harm, healthcare team members including nurses may receive little formal training and education in school. The purpose of the Doctor of Nursing Practice (DNP) scholarly …

Pregnancy Education In Rural Areas, Kayla Tinsley

Doctor of Nursing Practice Scholarly Project

Educating of the pregnancy population before, during and after pregnancy can help to ensure a healthy pregnancy and in turn reduce maternal mortality. The purpose of this research project was to understand education provided in the clinic and hospital setting in a rural area by those who take care of and talk to pregnant women and their support persons. A descriptive research design was utilized to discover the important education topics that are discussed, and the routine tests that are done throughout the pregnancy, during labor and at delivery, and even ask how prepared they feel they are equipped to …

Pre-Pulse Inhibition In Mutated Mice: Studying Compromised Microglial Cells To Discover New Genetic Connections To Autism, Bailey R. Kramarik

Senior Honors Projects, 2020-current

Microglial cells “play a pivotal role in refining neural networks during early critical periods” (Gabriele & Gray, 2020, p. 1). A disturbance in the functioning of these microglial cells contribute to specific characteristics of some neurodevelopmental disorders- including autism spectrum disorder. In this study, we used a mouse model to study disruptions in cell activity, as understanding the biological and genetic background of autism spectrum disorder could help us provide better treatment and therapy options to those diagnosed.

The mutated mice in this experiment have microglial cells with “compromised fractalkine signaling” (Gabriele & Gray, 2020, p. 4-5). We studied multimodal …

Cardiovascular Risk Stratification In Diabetic Retinopathy Via Atherosclerotic Pathway In Covid-19/Non-Covid-19 Frameworks Using Artificial Intelligence Paradigm: A Narrative Review., Smiksha Munjral, Mahesh Maindarkar, Puneet Ahluwalia, Anudeep Puvvula, Ankush Jamthikar, Tanay Jujaray, Neha Suri, Sudip Paul, Rajesh Pathak, Luca Saba, Renoh Johnson Chalakkal, Suneet Gupta, Gavino Faa, Inder M Singh, Paramjit S Chadha, Monika Turk, Amer M Johri, Narendra N Khanna, Klaudija Viskovic, Sophie Mavrogeni, John R Laird, Gyan Pareek, Martin Miner, David W Sobel, Antonella Balestrieri, Petros P Sfikakis, George Tsoulfas, Athanasios Protogerou, Durga Prasanna Misra, Vikas Agarwal, George D Kitas, Raghu Kolluri, Jagjit Teji, Mustafa Al-Maini, Surinder K Dhanjil, Meyypan Sockalingam, Ajit Saxena, Aditya Sharma, Vijay Rathore, Mostafa Fatemi, Azra Alizad, Vijay Viswanathan, Padukode R Krishnan, Tomaz Omerzu, Subbaram Naidu, Andrew Nicolaides, Mostafa M Fouda, Jasjit S Suri

Heart and Vascular Articles

Diabetes is one of the main causes of the rising cases of blindness in adults. This microvascular complication of diabetes is termed diabetic retinopathy (DR) and is associated with an expanding risk of cardiovascular events in diabetes patients. DR, in its various forms, is seen to be a powerful indicator of atherosclerosis. Further, the macrovascular complication of diabetes leads to coronary artery disease (CAD). Thus, the timely identification of cardiovascular disease (CVD) complications in DR patients is of utmost importance. Since CAD risk assessment is expensive for low-income countries, it is important to look for surrogate biomarkers for risk stratification …

Factors Influencing Vaccination Rates In Children Under Two In Southeast Kansas, Danielle Bennett

Doctor of Nursing Practice Scholarly Project

Introduction

A large Federally Qualified Health Center (FQHC) in Southeast Kansas has a 37% compliance of children completing the recommended combo 10 primary vaccination series before their second birthday. An additional 20% of children would be compliant if the flu vaccine was excluded, raising the compliance rate to 57%. This is still below the national average of 68-75%, leaving many children in Southeast Kansas and northeast Oklahoma unprotected from preventable childhood diseases.

Purpose

The purpose of this scholarly project was to identify barriers to vaccination, including vaccine hesitancy and socioeconomic barriers affecting completion of the primary vaccine series, or combo …

Improving Family Involvement Through Dementia Education Using A Video Sharing Service, Marissa Lynn Bernabe

Doctor of Nursing Practice Scholarly Project

Dementia is a growing issue among healthcare organizations within the United States (U.S.) with approximately 5.7 million individuals diagnosed. These numbers of affected individuals are expected to increase and reach approximately 152 million by 2050 globally. Dementia is a progressive disease of cognitive loss. Establishing goals or items the patient can perform can have a positive impact on patient care by allowing for a collaborative approach and initiating the family as necessary participants in the care of the dementia patient. Video sharing services such as YouTube have made learning easily accessible for a multitude of varied reasons.

A descriptive quality …

Genetics And Genomics In Nursing Practice: Assessing Barriers, Facilitators, And Tailoring Implementation Strategies, Jaanna Guillory

Doctor of Nursing Practice Scholarly Project

The Essential Nursing Competencies and Curricula Guidelines for Genetics and Genomics were published in 2006. These guidelines define the minimal competency in genetics expected of all nurses regardless of role, specialty, or level of education. However, research indicates that nurses lack knowledge and confidence in their role in genetics/genomics.

This quality improvement project aimed to assess barriers and facilitators of genetics/genomics integration into nursing. This study followed a cross-sectional design emphasizing a representative subset of the nursing practicing community at the Veterans Healthcare System of the Ozarks. Participants were invited to complete the Genetics and Genomics in Nursing Practice Survey …

Improving Palliative Care Education In The Acute Hospital Setting, Maria Klug

Doctor of Nursing Practice Scholarly Project

As the geriatric population grows rapidly, the importance of utilizing and understanding palliative services continues to rise. Although palliative and hospice care are included in different healthcare courses, misconceptions and lack of knowledge continue to serve as barriers to the utilization of palliative care. The purpose was to assess knowledge, improve palliative care education, and increase understanding of the perspectives of the interdisciplinary team involved in acute patient care. The setting was the telemetry unit in a 300-bed acute care Kansas hospital. A mixed design was utilized with a goal of quality improvement in the use of palliative care. The …

Provider Education On Physical Activity For Older Adults, Joseph Morris

Doctor of Nursing Practice Scholarly Project

PROVIDER EDUCATION ON PHYSICAL ACTIVITY FOR OLDER ADULTS

An Abstract of the Scholarly Project by

Joseph Morris

The purpose of this study was to educate nursing staff and providers on the importance of physical activity for older adults to prevent functional decline and maintain quality of life. The project was conducted online using Qualtrics survey software. Data was collected from October 25, 2021 to November 25, 2021. Nursing staff and healthcare providers (physicians, nurse practitioners and physician assistants) that are actively practicing medicine and have experience interacting with older adults participated by completing a two-part survey. The survey consisted of …

Reducing The Stigma Associated With Maternal Substance Use Disorder In A Rural Midwest Hospital And Clinic, Jami Vineyard

Doctor of Nursing Practice Scholarly Project

The purpose of this study was to determine if an educational resource provided to maternal healthcare providers, more specifically, providers in a Midwest regional hospital and clinic, would reduce the stigma associated with maternal substance use disorder (SUD). This project also aimed at increasing provider knowledge on the disease process of maternal SUD and current treatment guidelines.

A quantitative research design was used for this study. There was no control group; therefore, it is a quasi-experimental study. Qualtrics were utilized to design a pre-test and post-test. An email including a brief description of the study, an invitation to participate, and …

An Educational Project On Guidelines Of Treating Respiratory Syncytial Virus And Bronchiolitis In Rural Pediatric Patients, Mallory Revell

Doctor of Nursing Practice Scholarly Project

Bronchiolitis is the leading cause of hospital admission for infants. Eighty percent of bronchiolitis cases are caused by the respiratory syncytial virus (RSV). While guidelines on the treatment of RSV/bronchiolitis have been published since 2006, the literature reveals that they are not widely followed. After completing a literature review on the current evidence-based treatment guidelines of RSV/bronchiolitis, nurses from a rural hospital in southeast Kansas were educated on these guidelines to improve their knowledge regarding treatments for RSV/bronchiolitis pediatric patients. This study utilized a pretest-posttest design to determine the knowledge gained after the educational presentation. The nurses completed a survey …

Improving Venous Thromboembolism Prophylaxis Knowledge Among Registered Nurses On A Medical-Surgical Inpatient Unit In The Midwest, Theresa Umscheid

Doctor of Nursing Practice Scholarly Project

Venous thromboembolism (VTE) is the third most common vascular disease and includes approximately 900,000 cases annually in the United States. The purpose of this quality improvement project was to enhance education regarding VTE prophylaxis for registered nurses on a medical-surgical inpatient unit at a hospital in the Midwest. This study was initiated due to one nurse’s perception that staff on this unit lacked confidence and expertise on the importance of VTE prophylaxis interventions. Participants completed a VTE knowledge pretest, followed by an educational intervention on VTE prophylaxis utilizing Health Stream. After the intervention, participants completed a VTE knowledge post-test. The …

Sporadic Worldwide “Clusters” Of Feed Driven Zilpaterol Identifications In Racing Horses: A Review And Analysis, Jacob Machin, Kimberly Brewer, Abelardo Morales Briceno, Clara Fenger, George Maylin, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Zilpaterol is a β2-adrenergic agonist medication approved in certain countries as a cattle feed additive to improve carcass quality. Trace amounts of Zilpaterol can transfer to horse feed, yielding equine urinary “identifications” of Zilpaterol. These “identifications” occur because Zilpaterol is highly bioavailable in horses, resistant to biotransformation and excreted as unchanged Zilpaterol in urine, where it has a 5 day or so terminal half-life.

In horses, urinary steady-state concentrations are reached 25 days (5 half-lives) after exposure to contaminated feed. Zilpaterol readily presents in horse urine, yielding clusters of feed related Zilpaterol identifications in racehorses. The first cluster, April …

Information And Communication Technology Applications And Use In Medical Records And Information Management In Selected Hospitals In Ijebu Ode Local Government Area, Ogun State., Aderonke Ogungbade Cln, Oluwatobi Abdul Mr

Library Philosophy and Practice (e-journal)

This study investigated the information and communication technology application and use in medical records and information management in selected hospitals in Ijebu-Ode Local Government Area of Ogun State. The Objectives of the study found out the level of application and compliance of ICT and also investigated the challenges facing the application. The survey research design was adopted while total enumeration sampling technique was used in the selection of samples. Questionnaire was used to gather data for this study while mean and standard deviation frequency counts and percentages was used in data analysis. Findings shows that the information and communication tools …

Does Nurses Confidence Improve After Attending A Training For Teaching Home Infusion Patients?, Carol Menorah Young Dnp

Doctor of Nursing Practice Scholarly Projects

Discharge can be a difficult step for patients and their families and a challenging task for nurses. Poor instructions have a negative impact on the patient population. In addition, improper and incomplete discharge information negatively affects the posthospital recovery period and may cause the patient to return to the hospital for the same episode of care. Returning to the hospital emergency room or readmission for the same episode of care will increase the dangers to the patient’s health and recovery plan and increase the cost of individual healthcare. The patient population ranks the quality of discharge information via their responses …

Anxiety-Like Behavior And Anxiolytic Treatment In The Rett Syndrome Natural History Study, Caroline B Buchanan, Robin C Ryther, Et Al.

2020-Current year OA Pubs

BACKGROUND: Rett syndrome (RTT) is a neurodevelopmental disorder most often related to a pathogenic variant in the X-linked MECP2 gene. Internalizing behaviors appear to be common, but standard methods of diagnosing anxiety are not readily applied in this population which typically has cognitive impairment and limited expressive language. This study aims to describe the frequency of anxiety-like behavior and anxiolytic treatments along with associated clinical features in individuals with RTT.

METHODS: Parental reports and medication logs provided data from 1380 females with RTT participating in two iterations of the multicenter U.S. RTT Natural History Study (RNHS) from 2006 to 2019. …

Global Community Of Practice: A Means For Capacity And Community Strengthening For Health Professionals In Low- And Middle-Income Countries, Allison Silverstein, Amy Benson, Catriona Gates, Diane Nguyen

Faculty, Staff and Students Publications

BACKGROUND: Low- and middle-income countries face distinct challenges in providing health care services and training. The community of practice (CoP) has been described as a method of facilitating much-needed connections and conversations on this topic and has been adapted over time to include virtual CoPs. We describe the development and evaluation of a global Clinical Lead Forum (CLF) using a CoP framework to structure informal continuing professional development (CPD) and enhance the capacity of health care professionals in low- and middle-income countries.

METHODS: Baylor College of Medicine International Pediatric AIDS Initiative (BIPAI) and its network of affiliated, independent non-governmental organizations …