Medicine and Health Sciences Commons^™

Decreasing Falls On A Locked Inpatient Psychiatric Unit, Terri Fitzpatrick

Doctor of Nursing Practice Final Manuscripts

Purpose: The purpose of this project was to implement an RN nursing staff education on the fall risk assessment tool in effort to decrease falls on one adult locked inpatient psychiatric unit. The assumption was that an educational review of the fall risk variables for inpatient psychiatric patients and subsequent initiation of a fall risk care plan would lead to decreased falls.

Background: A fall can be defined as a sudden unintentional change in position causing an individual to descend to a lower level or onto an object, the floor or ground, or another surface with or without injury. Review …

Spatial Transcriptomics Reveals Metabolic Changes Underly Age-Dependent Declines In Digit Regeneration, Robert J. Tower, Emily Busse, Josue Jaramillo, Michelle Lacey, Kevin Hoffseth, Anyonya R. Guntur, Jennifer Simkin, Mimi C. Sammarco

School of Medicine Faculty Publications

De novo limb regeneration after amputation is restricted in mammals to the distal digit tip. Central to this regenerative process is the blastema, a heterogeneous population of lineage-restricted, dedifferentiated cells that ultimately orchestrates regeneration of the amputated bone and surrounding soft tissue. To investigate skeletal regeneration, we made use of spatial transcriptomics to characterize the transcriptional profile specifically within the blastema. Using this technique, we generated a gene signature with high specificity for the blastema in both our spatial data, as well as other previously published single-cell RNA-sequencing transcriptomic studies. To elucidate potential mechanisms distinguishing regenerative from non-regenerative healing, we …

The Ventromedial Hypothalamic Nucleus: Watchdog Of Whole-Body Glucose Homeostasis, Longlong Tu, Makoto Fukuda, Qingchun Tong, Yong Xu

Children’s Nutrition Research Center Staff Publications

The brain, particularly the ventromedial hypothalamic nucleus (VMH), has been long known for its involvement in glucose sensing and whole-body glucose homeostasis. However, it is still not fully understood how the brain detects and responds to the changes in the circulating glucose levels, as well as brain-body coordinated control of glucose homeostasis. In this review, we address the growing evidence implicating the brain in glucose homeostasis, especially in the contexts of hypoglycemia and diabetes. In addition to neurons, we emphasize the potential roles played by non-neuronal cells, as well as extracellular matrix in the hypothalamus in whole-body glucose homeostasis. Further, …

Impact Of Hospital Characteristics And Governance Structure On The Adoption Of Tracking Technologies For Clinical And Supply Chain Use: Longitudinal Study Of Us Hospitals, Xiao Zhu, Youyou Tao, Ruilin Zhu, Dezhi Wu, Wai-Kit Ming

Publications

BACKGROUND: Despite the increasing adoption rate of tracking technologies in hospitals in the United States, few empirical studies have examined the factors involved in such adoption within different use contexts (eg, clinical and supply chain use contexts). To date, no study has systematically examined how governance structures impact technology adoption in different use contexts in hospitals. Given that the hospital governance structure fundamentally governs health care workflows and operations, understanding its critical role provides a solid foundation from which to explore factors involved in the adoption of tracking technologies in hospitals. OBJECTIVE: This study aims to compare critical factors associated …

Food Insecurity And Health-Related Concerns Among Elementary Schoolteachers During The Covid-19 Pandemic, Fangyu Li, Nivedhitha Parthasarathy, Feng Zhang, Ru-Jye Chuang, Mallika Mathur, Mike Pomeroy, Jacqueline Noyola, Christine M Markham, Shreela V Sharma

Faculty, Staff and Student Publications

INTRODUCTION: US school systems underwent major upheaval, including closures, implementation of virtual and/or hybrid learning, and stringent infection mitigation protocols, during the initial phase of the COVID-19 pandemic. We aimed to examine the association between food insecurity and perceived health, perceived stress, and social determinants of health concerns among elementary schoolteachers serving predominantly low-income children during the COVID-19 pandemic.

METHODS: Brighter Bites, a nonprofit organization that weekly distributes fresh fruits and vegetables and nutrition education materials to more than 300 schools serving racial and ethnic minority populations with low income, conducts annual surveys of participating teachers to help determine subsequent …

Lessons Learned From The World Health Organization’S Late Initial Response To The 2014-2016 Ebola Outbreak In West Africa, Chulwoo Park

Faculty Research, Scholarly, and Creative Activity

The purpose of this article is to 1) examine the role of the World Health Organization (WHO) in controlling infectious disease outbreaks, 2) evaluate if the WHO’s initial response to the 2014-2016 Ebola crisis was appropriate, 3) evaluate current WHO’s efforts to prevent future disease outbreaks after the Ebola elimination, and 4) suggest how WHO should be further reformed to provide prompt and accurate guidance to multi-sectoral health stakeholders at local, national, regional and global level for effective surveillance preparedness and response. This is a non-systematic narrative literature review. The articles from PubMed, Scopus, Medline, books, WHO documents and websites, …

Segmentation Of Infant Brain Using Nonnegative Matrix Factorization, Norah Saleh Alghamdi, Fatma Taher, Heba Kandil, Ahmed Sharafeldeen, Ahmed Elnakib, Ahmed Soliman, Yaser Elnakieb, Ali Mahmoud, Mohammed Ghazal, Ayman El-Baz

All Works

This study develops an atlas-based automated framework for segmenting infants' brains from magnetic resonance imaging (MRI). For the accurate segmentation of different structures of an infant's brain at the isointense age (6-12 months), our framework integrates features of diffusion tensor imaging (DTI) (e.g., the fractional anisotropy (FA)). A brain diffusion tensor (DT) image and its region map are considered samples of a Markov-Gibbs random field (MGRF) that jointly models visual appearance, shape, and spatial homogeneity of a goal structure. The visual appearance is modeled with an empirical distribution of the probability of the DTI features, fused by their nonnegative matrix …

Process Evaluation Of An Academic-Community-Government Partnership To Reduce Liver Diseases Attributable To Hepatitis B Virus., Daisy Le, Min Jeong Jeon, Annie Coriolan Ciceron, Y Tony Yang, Jane Pan, Hee-Soon Juon, Sherrie F Wallington

Department of Medical Oncology Faculty Papers

BACKGROUND: Racial/ethnic minorities have higher incidence and mortality rates of liver cancer, or hepatocellular carcinoma, than non-Hispanic Whites. As such, the Washington-Baltimore Metropolitan Area Hepatitis B Virus (WB-HBV) Demonstration Project, a community-based participatory research (CBPR)-driven academic-community-government (ACG) partnership, was established in 2019 to address disparities and implement strategies to improve the HBV screening and vaccination infrastructure for at-risk communities. CBPR is a partnership of community members, organizational leaders, and academic researchers with a common aim to collectively share and contribute their input at every phase of the project. Herein, we describe the process evaluation of the WB-HBV Project and extract …

Effect Of Botox And Therapy On Spasticity In Cerebral Palsy: A Critically Appraised Topic, Rachel Bray Mot/S, Tatum Cabot Mot/S, Peyton Clark Mot/S, Cameron Goodman Mot/S, Tarason Moore Mot/S, Claire Napier Mot/S

Master of Occupational Therapy Student Critically Appraised Topics

Children diagnosed with Cerebral Palsy often experience upper limb spasticity. Research has shown Botox injections in combination with occupational therapy can reduce the effects of spasticity in the upper limb. This literature review aims to determine how long is the appropriate duration of occupational therapy to administer after Botox injections to see decreased spasticity in the upper limbs.

Effects Of Sensory Intervention On Neurological Development In The Neonatal Intensive Care Unit: A Critically Appraised Topic, Paulina Bullard Mot/S, Emma Gadberry Mot/S, Siham Sherif Mot/S, Virginia Strawn Mot/S, Courtney Travis Mot/S, Delaney Weller Mot/S

Master of Occupational Therapy Student Critically Appraised Topics

The final portfolio contains four research articles from both national and international journals. Study designs include a randomized clinical trial, a randomized control trial, a systematic review and meta-analysis, and an integrative review. All studies relate directly to components of the evidence-based practice question and will be used to recommend sensory intervention for neurological development of premature infants in the neonatal intensive care unit (NICU). One of the articles describes statistically significant effects. One of the articles describes both statistically significant and non-statistically significant effects of sensory intervention on neurological development of premature infants in the NICU. The other two …

Mediastinal Mass-Emergency Department, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Agenda (Pdf), School Of Medicine

Postbaccalaureate Research Education Program in Biomedical Sciences (PREP)

No abstract provided.

Skin Response: A Multidisciplinary Approach To Pressure Injury Prevention, Shannon E. Jagger Msn, Rn-Bc, Ne-Bc, Cpps, Deborah A. Saber Ph.D.. Rn, Ccrn-K, Patricia Poirier Ph.D., Rn

Journal of Nursing & Interprofessional Leadership in Quality & Safety

Hospital acquired pressure injuries (HAPIs) are listed as serious reportable events and classified as “never events.” Nevertheless, more than 2.5 million people develop HAPIs in the United States every year with 60,000 dying from associated complications. HAPI rates at the site of this quality improvement initiative were high and required intervention. As a result, the Skin Response (SR) initiative was developed to bring a multidisciplinary team to the bedside within 20 minutes of an identified skin concern. This team consisted of the bedside registered nurse (RN), RN leader, physician, facilitator, nutritionist, and wound RN. Through a team approach, SR assisted …

Sex Differences In The Immune Response To Chronic Periodontitis, John Huang, Amy Tsai, Ina Stelzer, Dorien Feyaerts, William Choi, David Vang, Edward Ganio, Dyani Gaudilliere, Brice Gaudilliere, Xiaoyuan Han

Excellence Day

Chronic Periodontitis (ChP) is an inflammatory condition that results from oral dysbiosis and host immune dysfunction. Epidemiologic evidence has shown that men are more susceptible to ChP than women. Despite gender differences in behavior and socioeconomic status influencing oral health, the biological sex-associated immunological mechanisms underlying the pathogenesis of ChP are unclear. The objective of this study is to identify sex differences in the immune responses to chronic periodontitis.

The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In Human Gecs, Kaitlyn Liu, Harmony Matshik Dakafay, David Ojcius, Cassio Silva

Excellence Day

A large body of evidence shows the harmful effects of cigarette smoke to oral and systemic health. Recently, a link between smoking and susceptibility to coronavirus disease 2019 (COVID-19) was proposed. Here, we examined the effects of cigarette smoke on SARS-CoV-2 infection in human gingival epithelial cells (GECs) to better understand the mechanisms involved in SARS-CoV-2 infection in cells of the oral cavity.

Assessment Of Mandibular Plane Changes Using Conventional Versus Miniscrew-Assisted Rapid Palatal Expansion In Adolescents, Michael Ricupito, Daniel Vorhees, Derek Skousen

Excellence Day

The objective of this study was to assess the cephalometric and transversal changes in growing patients (adolescents) using two different types of maxilla expanders: conventional rapid palatal expander (RPE) and miniscrew-assisted rapid palatal expander (MARPE). Our null hypothesis is that there are no significant differences between the two groups for the molar inclination, maxilla expansion amount, and mandibular plane changes.

Biomarkers Of Orthodontic Tooth Movement, Max Kazantcev, Kamal Thapaliya, Marie Tolarova, Miroslav Tolar

Excellence Day

Orthodontic tooth movement leads to remodeling of periodontal ligament, alveolar bone, and gingiva. Tooth movement is characterized by bone deposition at sites of tension and bone resorption at pressure sites. Due to a sterile inflammatory process in the PDL space, a flow rate of gingival crevicular fluid (GCF) is increased and its composition is modified. Various cell-signaling pathways are activated, which ultimately stimulate PDL turnover. Biochemical and cellular processes associated with orthodontic tooth movement may be better understood if we study changes of specific biomarkers in GCF during orthodontic therapy. Such information can be used clinically to choose a proper …

In-Vitro Composite Surface Analysis Using Foru Polishing Systems A Sem Study, Shreya Nerli

Excellence Day

To evaluate the effect of four polishing methods on the surface gloss of a composite.

Shared Decision Making In Scaling And Root Planing, José Verdugo, Lory Laughter, David W. Chambers

Excellence Day

Estimate the patient participation in decisions commonly arising in scaling and root planing as functions of the professionals’ preferences of dental hygienists, typical situations in this procedure, common approaches to patient interaction, and the interaction of these factors.

Diabetes, Periodontitis And The Oral Microbiome, Madison West, Kaitlin Liautaud, Charles Hunter Pitts, Michael Ricupito, Joshua Cho

Excellence Day

The association between diabetes mellitus and periodontitis has been studied thoroughly. However, the role of the oral microbiome in linking these two diseases still is not clear. The objective of this literature review is to search the current studies on oral dysbiosis in the two diseases and find out whether the oral microbiome could be a possible biomarker indicating diabetes in periodontal patients.

Cbct Analysis Of Root Resorption In Orthodontic Patients With Short Root Anomaly, Sani Zaidi, Kaiyuan Xu, Heesoo Oh, Jonas Bianchi

Excellence Day

The objective of this study was to evaluate the amount of root resorption after orthodontic treatment in patients with Short Root Anomaly (SRA) in comparison with control patients using Cone Beam Computed Tomography (CBCT). We hypothesized that patients with SRA present more susceptibility to root resorption during orthodontic treatment when compared to the normal population.

Covid-19 Wastewater Project: Validating Sars-Cov-2 Detection Techniques, David Kim, David Vang, David Ojcius, Der Thor

Excellence Day

This research was done to validate and test the current viral RNA detection techniques and to determine sensitivity and optimal temperature of RT-qPCR technique.

Relationship Between Cervical Vertebral Maturation And Chronological Age: A Mixed Longitudinal Study, Sudhashree Lingam, Garima Shrestha, Vijaylaxmi Nag, Aditi Ghosh, Hanisha Pasupulate, Heesoo Oh

Excellence Day

The cervical vertebrae have been proposed as a method of determining skeletal maturation.This study aimed to evaluate the relationship between chronologic age and the individual skeletal maturity as assessed by means of the cervical vertebral maturation (CVM) method.

The Role Of Inflammation In Epithelial-Mesenchymal Transition In Oral Squamous Cell Carcinoma: Literature Review, Preliminary Data, And Proposal Of Experiments, Rachel Choi, Jisoo Kim, Adria Frazier, Takahiro Chino

Excellence Day

The epithelial-mesenchymal transition (EMT) is a trans-differentiation process of epithelial cells into motile mesenchymal cells. It plays an integral role in embryonic development, wound healing and cancer progression. During EMT, epithelial cells lose their cellular polarity due to the loss of intercellular adhesion and acquire migratory and invasive characteristics associated with mesenchymal cells. EMT is tightly regulated by a number of distinct molecular processes which allow its initiation and progression to completion. These processes include activation of transcription factors, expression of specific cell-surface proteins, reorganization and expression of cytoskeletal proteins, production of extracellular matrix-degrading enzymes and changes in the expression …

Clostridium Difficile [Retired], Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Effects Of Animal-Assisted Therapy On Communication, Agitation And General Health In Individuals With Dementia Living In Long-Term Care Facilities And The Secondary Effects On Their Caregivers., Jenilee K. Woltman

Communication Disorders Theses, Dissertations, and Student Creative Activity

The use of animals for therapeutic purposes has existed for centuries. However, it was not until recently that people realized the human-animal interaction has potential effects on our overall health. Human-animal interaction positively impacts humans' social, emotional, and cognitive functions (Woods et al., 2005). This research encompasses two studies. Both studies examined the therapeutic effects of an animal-assisted therapy (AAT) dog presence on communication abilities and agitation of individuals with mild to severe dementia residing in a long-term care facility. Study 1 examined agitated behaviors, communications, and social interactions of older adults with dementia living in a long-term care facility …

2022-05-25_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

2022-05-25_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …

2022-05-25 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2022-05-25_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Wednesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …