Medicine and Health Sciences Commons^™

2020-05-08_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-05-08_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

2020-05-08_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-05-08_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Coronavirus Update 5-8-20, The Coronavirus Planning Team

University Briefings & Virtual Events

Connecticut Governor Ned Lamont came out with guidance for reopening colleges and universities. The good news is that the recommendations are in line with the discussions and planning that are already taking place among Sacred Heart’s task forces that are preparing for the fall semester and beyond in the wake of the coronavirus.

2020 County Health Rankings Tennessee Data And Updated Substance Abuse 2005-2019, Kelsey L. Grabeel, Jenny Moore

Faculty Publications

No abstract provided.

2020-05-08 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Ryen Ormesher, Lauren Tagliaferro Epler, Jenny Situ, Aly Raboff, John Powell, Alexandra Yingling, Cristian Bologa, Tudor I. Oprea, Gregory Mertz, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

UNM drug repurposing. NM cases. Doctors Without Borders. SNAP benefits online. NM 7th highest unemployment. Virtual LemonAid tonight. New N98 masks. Healthcare supply chain challenge. EMS lack resources. Infection risk in healthcare workers. COVID-19 on medical education. Human disinfectant chambers. Evidence of seroconversion. Dangers of considering herd immunity. Wastewater-based surveillance. More youths infected. Reconstructing ship spread. Pharmacoepidemiologic analysis. Clinicopathologic characteristics. Cancer treatment impact. Reduced voluntary psychiatric admission in Italy. Operating room management. Humidifiers reduce transmission. Phone contact tracing ethics. Call for patient database. Immunity certification program. Guidelines on tracheostomy, IBD, nose bleeding, pituitary tumors, and hematopoietic stem cells …

Factors Which Influence The Education Of Local Anesthesia In Dental Hygiene, Angela D. Cook, Angela D. Cook

Dental Hygiene ETDs

ABSTRACT Dental hygienists, like most students, learn according to formal curriculum that is defined by goals, competencies, and required subject matter for examinations.¹ They also learn through an intense socialization process known as “the hidden curriculum”. The “hidden curriculum” is not defined in student textbooks nor classroom lectures, but is demonstrated through case studies, research, and an experience shared between colleagues.¹ The purpose of this study was to assess the determining factors that influence what dental hygiene instructors are teaching hygiene students on the use of articaine when administering dental blocks, and to assess if the “hidden curriculum” …

Synaptic Dysfunction Induced By Glycine-Alanine Dipeptides In C9orf72-Als/Ftd Is Rescued By Sv2 Replenishment., Brigid K Jensen, Martin H Schuldi, Kevin Mcavoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma, Aaron R. Haeusler, Dieter Edbauer, Piera Pasinelli, Davide Trotti

Department of Neuroscience Faculty Papers

The most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is an intronic hexanucleotide repeat expansion in the C9orf72 gene. In disease, RNA transcripts containing this expanded region undergo repeat-associated non-AUG translation to produce dipeptide repeat proteins (DPRs), which are detected in brain and spinal cord of patients and are neurotoxic both in vitro and in vivo paradigms. We reveal here a novel pathogenic mechanism for the most abundantly detected DPR in ALS/FTD autopsy tissues, poly-glycine-alanine (GA). Previously, we showed motor dysfunction in a GA mouse model without loss of motor neurons. Here, we demonstrate that mobile …

Difference In Stigma Between Anorexia Nervosa, Bulimia Nervosa, And Binge Eating Disorder, And The Effect Of Eating Disorder Symptomology On Stigma In College Students, Ashley A. Matkins

Senior Honors Projects, 2020-current

Background: Eating disorders (ED) are mental illnesses characterized by unhealthy eating and exercise habits. These disorders are common in college students and, like other mental illnesses, eating disorders are highly stigmatized.

Objectives: This study evaluated how college students perceived anorexia nervosa, bulimia nervosa, and binge eating disorder, and the effect of eating disorder symptomology on stigma.

Methods: Participants were randomized to receive one of three vignettes depicting an ED. The study used the Universal Stigma Survey (USS), the Eating Disorder Examination Questionnaire (EDEQ), and demographic questions to evaluate stigma, symptomology as well as their familiarity with, and diagnosis of eating …

The Correlation Between Personal Stressors, Anxiety And Caffeine Consumption Among Jmu Faculty, Erica B. Larocca

Senior Honors Projects, 2020-current

This study investigates the relationships between caffeine consumption, stress and anxiety among faculty at James Madison University. This was examined using a mixed methods study with a sample of twenty undergraduate faculty members from all Academic Colleges besides the College of Education. Quantitative data serves to provide descriptive statistics as well as data from the Generalized Anxiety Disorder-7 scale and the Caffeine Expectancy Scale. Qualitative data serves to learn about the motivations and habits surrounding caffeine, and about the stressors and anxieties specific to faculty members. Anxiety and caffeine are reported to have an association (p=0.656). It was found that …

Revealing The Impact Of Singing In An Aphasia Group, Ava L. Barton

Senior Honors Projects, 2020-current

Aphasia is an acquired, neurogenic language disorder that affects an individual’s ability to express and comprehend language to varying degrees. Individuals with aphasia are restricted in their ability to communicate effectively and as a result, experience decreased quality of life and marked psychosocial consequences. There are numerous interventions that target the language symptoms associated with aphasia. However, social groups, such as book clubs, address both the language and psychological needs of individuals with aphasia. This project explored spontaneous moments of singing that occurred within an aphasia book club. Twenty-four moments of singing were identified and analyzed from six previously recorded …

Assessing The Health Literacy Levels Of Diabetic Patients Located In Rural Southeast Kansas, Meghan Murray

Doctor of Nursing Practice Scholarly Project

Data shows that limited health literacy is prevalent throughout the United States. This data has also found a correlative relationship between limited health literacy and poor health outcomes. An individual’s health literacy level affects many areas of their health, including their ability to effectively manage chronic diseases, such as diabetes mellitus. Awareness of an individual’s health literacy level allows for targeted interventions and a potential improvement for a patient’s health outcomes. The Newest Vital Sign (NVS) is a validated screening tool that allows for the identification of a patient’s likely health literacy level. The purpose of this Doctor of Nursing …

British Eugenics Failure And Success, Angela Gallagher

Electronic Theses and Dissertations

The historical narrative of eugenics often focuses on those eugenic societies and movements that ‘succeeded’ in part or in full in achieving a eugenic society. Less studied are those societies that failed, whether due to social backlash or internal incoherence. The British Eugenic Educational Society as the foundational point of eugenics, has therefore been overlooked as a result of it’s perceived lack of contribution to eugenic thought and its failure to pass eugenic legislation. Founded by Francis Galton, the originator of the philosophy of eugenics, the British Eugenic Educational Society should have been successful given it’s reputation and the numerous …

Exploring The Relationship Between Dietary Self-Monitoring With A Mobile App And Weight Change, Jason Payne

Electronic Theses and Dissertations

Background: Approximately 70% of the adult population in the United States has overweight or obesity and increased risk for developing chronic diseases. Dietary self-monitoring adherence using a paper diary is associated with weight loss; however, few studies have examined this association with dietary self-monitoring apps. Objectives: 1) explore if an association exists between app-based dietary self-monitoring and weight change among adults with overweight or obesity and 2) explore the relationships between the frequency, consistency, and completeness of self-monitoring and weight change. Methods: Participants self-monitored dietary intake for 8 weeks using the app Calorie Counter by FatSecret. Participants were assigned …

Coping Behaviors Of African Americans With Inflammatory Bowel Disease: A Focused Ethnography, Patricia Scott

Electronic Theses and Dissertations

Background: Increasing numbers of African Americans are being diagnosed with inflammatory bowel disease (IBD) in the United States (Dahlhamer, Zammitti, Ward, Wheaton, & Croft, 2016). Little is known about the influence of culture on coping with the disease. Method: Twelve African American adults with IBD were interviewed and observed using a focused ethnography. Results: Data analysis resulted in four major themes: (1) spending time living in the bathroom; (2) time and food restricted eating practices and cultural food avoidance; (3) dealing with a life full of stress; and (4) the practice of seclusion to promote health. Discussion: Participants described coping …

Caring For Victims Of Child Maltreatment: Pediatric Nurses’ Moral Distress And Burnout, Angela Karakachian

Electronic Theses and Dissertations

Background: Moral distress is a significant concern for nurses as it can lead to burnout and intentions to leaving the profession. Pediatric nurses encounter stressful and ethically challenging situations when they care for victims of suspected child maltreatment. Data on pediatric nurses’ moral distress in this situation are lacking, as most research in this field has been done in adult inpatient and intensive care units.

Aims: The purpose of this study was to describe pediatric nurses’ moral distress and determine the impact of caring for victims of suspected child maltreatment on nurses’ moral distress, burnout, and intention to leave.

Design …

Projected Deaths Of Despair From Covid-19, Stephen Petterson, John M. Westfall, Benjamin F. Miller

Articles, Abstracts, and Reports

More Americans could lose their lives to deaths of despair, deaths due to drug, alcohol, and suicide, if we do not do something immediately. Deaths of despair have been on the rise for the last decade, and in the context of COVID-19, deaths of despair should be seen as the epidemic within the pandemic. The goal of this report is to predict what deaths of despair we might see based on three assumptions during COVID-19: economic recovery, relationship between deaths of despair and unemployment, and geography. Across nine different scenarios, additional deaths of despair range from 27,644 (quick recovery, smallest …

Scald Injury-Induced T Cell Dysfunction Can Be Mitigated By Gr1+ Cell Depletion And Blockage Of Cd47/Cd172a Signaling, Nadine Beckmann, Franziska Huber, Marc Hanschen, Barbara St. Pierre Schneider, Vanessa Nomelli, Charles C. Caldwell

Nursing Faculty Research

Infection is a common and severe complication of burn injury: Sepsis accounts for 47% of postburn mortality. Burn-induced T cell suppression likely contributes to the increased infection susceptibility in burn patients. However, little is known about the kinetics of T cell dysfunction after burn and its underlying mechanisms. In this study, we show in a murine scald injury model that T cell activation of both CD4+ and CD8+ T cells as well as T cell cytokine production is suppressed acutely and persistently for at least 11 days after burn injury. Purified T cells from scald-injured mice exhibit normal T cell …

Endobronchial Tuberculosis: A Rare Presentation, Nadeem Kassam, Omar M. Aziz, Samina Somji, Grace Shayo

Internal Medicine, East Africa

Endobronchial tuberculosis (EBTB) is an infection of the tracheobronchial tree by Mycobacterium tuberculosis. It is common among young females. Patient can present with fever, cough, wheeze, with or without any constitutional symptoms. It presents as a diagnostic dilemma, as patient sputum smear can be false negative. CT scan may or may not show any abnormality, or any endobronchial lesion. Bronchoscopy with bronchoalveolar lavage and biopsy offers the diagnostic choice. We hereby report a case of a young immunocompetent Asian female who was found to have endobronchial pathology, leading to diagnosis and timely therapy.

Risk Factors Associated With Pressure Injury In Pediatric Congenital Heart Disease Patients, Ashlee Shields

Electronic Theses and Dissertations

Pediatric congenital heart disease (CHD) patients have unique risk factors associated with the pathophysiology of abnormal heart function. This vulnerable population is likely at an increased risk of acquiring a pressure injury during hospitalization. There are limited studies that include congenital heart disease patients and more specifically, factors unique to these patients. The purpose of this study was to identify risk factors associated with development of pressure injury in pediatric CHD patients. This retrospective study used a convenience sample from hospital-acquired data including subjects with congenital heart disease. The results demonstrated an association between pressure injury development and variables both …

Gene Delivery To The Blood-Brain Barrier For Ischemic Stroke Therapy, Wanzhu Zhao

Electronic Theses and Dissertations

Stroke is a major cause of death in the United States. We aim to develop safe and efficient approaches for the treatment of stroke. Regenerative therapies have been identified as the major need for curing stroke [1]. We explored two different carriers (poly (ethylene glycol)_5k-poly (L-aspartate-diethylenetriamine)₄₈ (PEG-DET) / Pluronic P84 (P84) and exosomes (EXOs) / microvesicles (MVs)) to deliver brain-derived neurotrophic factor (BDNF) plasmid DNA (pDNA), a functional gene encoding a neurotrophin. In the first project, our data showed that DNA nanoparticles (NPs) with 0.03% P84 was a promising formulation to deliver Luciferase pDNA into immortalized human …

Pilot Study Exploring The Effect Of Targeted Cox-2 Inhibition In Macrophages Responding To Neuronal Injury; Promoting Enhanced Axonal Regeneration, Alyssa Brauckmann

Electronic Theses and Dissertations

Celecoxib nanoemulsion (CXB-NE) has been developed as a macrophage targeted analgesics by Dr. Janjic and her team at Duquesne University, (Janjic et al, 2018; Liu et al, 2020; Saleem et al, 2019b; Vasudeva et al, 2014). The CXB-NE nanoemulsion carrying a Nonsteroidal Anti-inflammatory (NSAID) inhibitor of COX-2 activity result in a reduction in PGE2 expression in macrophages. Using CXB-NE in rats that have peripheral nerve injury constricting the sciatic nerve relieves hypersensitivity, a pain-like behavior. The treatment also decreases inflammation associated with this chronic constriction injury (Janjic et al, 2018; Saleem et al, 2019b; Stevens et al, 2019). In this …

Demonstrable Effect Of Vocal Changes On Singing Voices Of Post-Menopausal Women, Haley K. Griffith

Senior Honors Projects, 2020-current

There is little research concerning the impacts of menopause on the female singing voice, and few research studies examine any treatment methods or exercises to help sustain vocal quality throughout and after menopause. To determine areas in which more detailed studies could be completed, I completed a thorough literature review of current research studies that investigate relationships between menopause and the voice. Many studies examined vocal symptoms of menopause, such as a lowered fundamental frequency (F0) and decreased vocal quality. However, there exists no formally researched or published vocal exercises that help to mitigate these menopausal voice symptoms.

In response, …

The Short Variant Of Optic Atrophy 1 (Opa1) Improves Cell Survival Under Oxidative Stress., Hakjoo Lee, Sylvia B Smith, Shey-Shing Sheu, Yisang Yoon

Center for Translational Medicine Faculty Papers

Optic atrophy 1 (OPA1) is a dynamin protein that mediates mitochondrial fusion at the inner membrane. OPA1 is also necessary for maintaining the cristae and thus essential for supporting cellular energetics. OPA1 exists as membrane-anchored long form (L-OPA1) and short form (S-OPA1) that lacks the transmembrane region and is generated by cleavage of L-OPA1. Mitochondrial dysfunction and cellular stresses activate the inner membrane-associated zinc metallopeptidase OMA1 that cleaves L-OPA1, causing S-OPA1 accumulation. The prevailing notion has been that L-OPA1 is the functional form, whereas S-OPA1 is an inactive cleavage product in mammals, and that stress-induced OPA1 cleavage causes mitochondrial fragmentation …

The Effects Of Acute Exercise And Psychological Stress On Episodic Memory, Lauren Koehler

Honors Theses

Research has suggested that exercise has an effect on memory function. Studies have also shown that exercise mitigates the effects of stress. The relationship between exercise and stress in regard to memory function is noteworthy. There has been little research on this relationship in young adults. This thesis discusses the effects of acute exercise on the episodic memory of young adults when they are exposed to a psychosocial stressor. The results of the research study show that acute aerobic exercise before memory encoding or consolidation was not associated with memory function after exposure to a stressor. Future research in this …

Audibility, Cost-Acceptibility And Cosmetic Appearance Of Iqbuds Boost In Adults Over The Age Of 50, Madison Dacus, Vishakha Rawool

Honors Theses

Background: Hearing loss affects 48 million Americans and up to 86% of all adults with hearing loss may not wear hearing aids. Untreated hearing loss is associated with social withdrawal, depression, stress, loss of income, and dementia. Even so, people still tend not to buy or wear hearing aids for a variety of reasons. One recently suggested solution to this problem is low-cost, over the counter (OTC) hearing aids, nicknamed “hearables” This study evaluated the audibility, cost-acceptability and cosmetic appearance of one OTC, IQBuds BOOST.

Methods: Fourteen men and 12 women over 50 years with a hearing loss participated in …

Feminism And Low Breastfeeding Rates In France, Megan Wadsworth

Honors Theses

Breastfeeding rates in France are among the lowest in high-income countries, indicating that French mothers do not breastfeed for nearly as long as is recommended by healthcare professionals and international health organizations. French government, society and conflicting feminist perspectives all influence the likelihood that mothers will breastfeed. The French government has regulations in place to protect women’s right to breastfeed in public and in the workplace, but it is unclear if these are truly beneficial for French women. French society is a seemingly inhospitable environment in which mothers do not feel safe and secure to breastfeed publicly. Motherhood and feminism …

Synthesis Of Pharmaceutical And Personal Care Products And Pesticide Metabolites Of Environmental Concern, Isaiah Edwards

Honors Theses

Human pollution of aquatic environments by introduction of pharmaceutical and personal care products (PPCPs) as well as agrichemicals presents a grave threat to the health of aquatic organisms. Many of these chemicals not only exhibit toxicity to the species of complex ecosystems at various levels but also undergo metabolic transformation into moieties that have different and sometimes more potent physiochemical profiles. PPCP and pesticides as well as their metabolites impact organisms via a number of different mechanisms, with the most serious arguably being endocrine disruption. Two emerging pollutants, gemfibrozil and bifenthrin, possess naturally occurring metabolites that were determined to warrant …

2020-05-08 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.