Medicine and Health Sciences Commons^™

Emerging Technologies In Healthcare: Analysis Of Unos Data Through Machine Learning, Reyhan Merekar

Student Theses and Dissertations

The healthcare industry is primed for a massive transformation in the coming decades due to emerging technologies such as Artificial Intelligence (AI) and Machine Learning. With a practical application to the UNOS (United Network of Organ Sharing) database, this Thesis seeks to investigate how Machine Learning and analytic methods may be used to predict one-year heart transplantation outcomes. This study also sought to improve on predictive performances from prior studies by analyzing both Donor and Recipient data. Models built with algorithms such as Stacking and Tree Boosting gave the highest performance, with AUC’s of 0.6810 and 0.6804, respectively. In this …

Implementing The Hodgson Red Yellow Green Mobilization Consensus Recommendation In A Medical And Surgical Icu: A Retrospective Study Exploring The Effectiveness Of An Early Mobilization Decision Protocol In Icu, Swati Patel

Seton Hall University Dissertations and Theses (ETDs)

Background: More than 4 million people are admitted annually to intensive care units (ICUs). Due to immobility, many ICU survivors experience significant cognitive, psychological, and physically disabling side effects regardless of admitting diagnosis. Multiple studies and quality improvement projects have shown the safety, feasibility, and benefits of early mobilization in the ICU setting. Hodgson et al (2014) published consensus recommendations for safe active mobilization of mechanically ventilated critically ill adults. To date, there is no standardized and simple triage protocol for identifying patients for early mobilization. No study so far has described operationalizing and implementing the Red-Yellow-Green system described …

Correlations Of Calf Muscle Macrophage Content With Muscle Properties And Walking Performance In Peripheral Artery Disease, Kate Kosmac, Marta Gonzalez-Freire, Mary M. Mcdermott, Sarah H. White, R. Grace Walton, Robert L. Sufit, Lu Tian, Lingyu Li, Melina R. Kibbe, Michael H Criqui, Jack M. Guralnik, Tamar S. Polonsky, Christiaan Leeuwenburgh, Luigi Ferrucci, Charlotte A. Peterson

Physical Therapy Faculty Publications

Background

Peripheral artery disease (PAD) is a manifestation of atherosclerosis characterized by reduced blood flow to the lower extremities and mobility loss. Preliminary evidence suggests PAD damages skeletal muscle, resulting in muscle impairments that contribute to functional decline. We sought to determine whether PAD is associated with an altered macrophage profile in gastrocnemius muscles and whether muscle macrophage populations are associated with impaired muscle phenotype and walking performance in patients with PAD.

Methods and Results

Macrophages, satellite cells, and extracellular matrix in gastrocnemius muscles from 25 patients with PAD and 7 patients without PAD were quantified using immunohistochemistry. Among patients …

Prediction Of Drug-Drug Interaction Potential Using Machine Learning Approaches, Joseph Scavetta

Theses and Dissertations

Drug discovery is a long, expensive, and complex, yet crucial process for the benefit of society. Selecting potential drug candidates requires an understanding of how well a compound will perform at its task, and more importantly, how safe the compound will act in patients. A key safety insight is understanding a molecule's potential for drug-drug interactions. The metabolism of many drugs is mediated by members of the cytochrome P450 superfamily, notably, the CYP3A4 enzyme. Inhibition of these enzymes can alter the bioavailability of other drugs, potentially increasing their levels to toxic amounts. Four models were developed to predict CYP3A4 inhibition: …

Surgical Versus Non-Surgical Intervention For Cholelithiasis, Nelya Dyak

Nursing Capstones

No abstract provided.

Subclinical Hypothyroidism And Its Relation To Cardiac Dysfunction, Brandon Anderson

Nursing Capstones

No abstract provided.

Precision Medicine And The Treatment Of Type 2 Diabetes Mellitus, Emily Stunek

Nursing Capstones

No abstract provided.

The Effects Of Pesticides And Hypothyroidism, Monica Larson

Nursing Capstones

No abstract provided.

Leveraging Volunteer Fact Checking To Identify Misinformation About Covid-19 In Social Media, Hyunuk Kim, Dylan Walker

Business Faculty Articles and Research

Identifying emerging health misinformation is a challenge because its manner and type are often unknown. However, many social media users correct misinformation when they encounter it. From this intuition, we implemented a strategy that detects emerging health misinformation by tracking replies that seem to provide accurate information. This strategy is more efficient than keyword-based search in identifying COVID-19 misinformation about antibiotics and a cure. It also reveals the extent to which misinformation has spread on social networks.

T31. Time To Talk Mental Health In Dubai: Describing A Sample Of Adolescent Help-Seekers Accessing Mental Health Services, Mariapaola Barbato, Shaikha Alhumairi, Shorouk Nafie, Baraa A Dhuhair, Nadia T Dabbagh

All Works

Abstract Background Most mental health disorders begin to develop in adolescence and early adulthood. These disorders account for a significant portion of hospitalization and other societal costs. The United Arab Emirates (UAE) has a rapidly growing population, one-third of which is below 25 years of age. The UAE government has pointed at mental health as one of the areas requiring attention and has approved a strategic plan supporting mental health research, education and promotion with a specific focus on youth (Dubai Mental Health Strategy 2021). The current study represents the first investigation aimed at characterizing youth who access mental health …

The Relationship Between Traumatic Brain Injuries, Impulsivity, And Crime, Brian Ramanauskas

Student Theses

The rate of traumatic brain injuries (TBIs) are increasing each year, impacting an estimated 1.4 million Americans. After further investigation, researchers have concluded that 8.5% of the general public sustains at least one TBI, whereas this number ranges from 25% to 87% in criminal populations. In the literature, impulsivity is frequently described as poorly conceived, prematurely expressed, or inappropriate behaviors. Additionally, poor impulse control has been shown to significantly impact the likelihood of criminal activity, increasing the rate of recidivism. The current study examined an archival dataset of 95 incarcerated individuals from a private correctional facility in a large mid-Atlantic …

Week Of May 18, 2020, New York Medical College

InTouch

• NYMC Launches M.S. in Biomedical Ethics and Humanities Program
• Albert Kwon, M.D., Joins Team to Develop Alternate Form of Ventilation Amid COVID-19 Crisis
• Medical Student Ebrahim Afshinnekoo Part of Project to Test NYC Subways for COVID-19
• NYMC Hosts Webinar to Address (Re)building Our Community
• SOM Seeks MMI Interviewers

Understanding Elements Involved In Active Racial And Ethnic Minority Recruitment Practices For Biopharmaceutical-Sponsored Clinical Trials: A Socio-Ecological Qualitative Inquiry, Rebecca Rae Johnson

Seton Hall University Dissertations and Theses (ETDs)

Inequitable participation in clinical trials continues to be a problem, and trial populations do not always reflect the demographics of the population that the investigational product will ultimately be treating. Because genetic differences between racial and ethnic groups affect the safety and efficacy of new treatments, it is important that standard of care decisions are made based on a representative population. The purpose of this study is to understand the socio-ecological elements that are involved in the active implementation of racial and ethnic minority recruitment practices for biopharmaceutical-funded trials in the United States. This general qualitative study was both descriptive …

Designing For Adolescent Mental Wellness: An Analysis Of Museum Education, Art Therapy, And Developmental Theory, Katherine Angela Himics

Seton Hall University Dissertations and Theses (ETDs)

Museums serve as therapeutic environments providing positive, arts engagement opportunities for visitors’ mental wellness and growth. Literature reveals that mental wellness programming in the museum environment predominantly serves adult audiences, yet the presentation of mental illness symptoms commonly begins during adolescence. In response, this study sought to provide an accessible, replicable structure for the design and implementation of adolescent mental wellness programming. Through a qualitative textual and content analysis, this study developed a series of recommendations for the development of said programming informed by the comparison of clinical art therapy practices, adolescent developmental theory, and the strengths of museum education.

Functionally Distinct High And Low Theta Oscillations In The Human Hippocampus., Abhinav Goyal, Jonathan Miller, Salman E Qasim, Andrew J Watrous, Honghui Zhang, Joel M Stein, Cory S Inman, Robert E Gross, Jon T Willie, Bradley Lega, Jui-Jui Lin, Ashwini Sharan, Chengyuan Wu, Michael R Sperling, Sameer A Sheth, Guy M Mckhann, Elliot H Smith, Catherine Schevon, Joshua Jacobs

Department of Neurosurgery Faculty Papers

Based on rodent models, researchers have theorized that the hippocampus supports episodic memory and navigation via the theta oscillation, a ~4-10 Hz rhythm that coordinates brain-wide neural activity. However, recordings from humans have indicated that hippocampal theta oscillations are lower in frequency and less prevalent than in rodents, suggesting interspecies differences in theta's function. To characterize human hippocampal theta, we examine the properties of theta oscillations throughout the anterior-posterior length of the hippocampus as neurosurgical subjects performed a virtual spatial navigation task. During virtual movement, we observe hippocampal oscillations at multiple frequencies from 2 to 14 Hz. The posterior hippocampus …

Lowering Antibiotic Resistance Utilizing Breastmilk, Moriah J. Harris

Honors College Theses

Antibiotic resistance is considered an emerging crisis in the healthcare world. This crisis has the potential to cause many bacterial diseases that cannot be cured using antibiotic drugs, which can lead to serious infections and death. There have been numerous studies that have found that sugars, proteins and protein-lipid complexes in breastmilk have antimicrobial properties. It has been proposed that these properties in breastmilk can help solve the antibacterial resistance crisis. This research project involved studying antibiotic resistance and how breastmilk can help solve this increasingly prevalent problem.

The implementation step of this research project involved a PowerPoint presentation detailing …

Measuring Learning And Engagement During Debriefing: A New Instrument, Shelly Jensen Reed

Faculty Publications

Background: Debriefing is considered to be where the bulk of learning takes place. Examination of debriefing is needed to help determine if facilitation methods effectively contribute to the learning process. More instruments are needed to evaluate all key debriefing elements, and no tools exist that evaluate participant engagement in the learning process.

Method: Kolb’s experiential learning theory was used to inform tool development. The focus of the new instrument is behaviors that indicate engagement with the learning process as the learner moves through Kolb’s learning cycle. A qualitative study of debriefing facilitators was performed, and a behaviorally anchored instrument was …

A National Study Of Undergraduate Nursing Students' Early Consideration Of Doctoral Education: What Characteristics Predict Students' Report Of Intention And Readiness To Continue Graduate Education Toward The Doctorate?, Renee Lynn Buonaguro

Theses & Dissertations

Statement of the Problem The looming nursing faculty shortage has already had a direct effect on schools of nursing. With our current understanding about enrollments needed to meet the demands of an adequately prepared healthcare workforce, attention needs to be directed toward the preparation of an adequate educator workforce. A consequence of not having doctorally prepared nursing faculty would result in an inadequate number of professors to accommodate the 70,000 applicants who are desiring to pursue their nursing degrees. One solution to the faculty shortage is to vastly increase the number of doctorally prepared faculty earlier in their careers. This …

The Effect Of Empathy On Compassion Fatigue And Quality Of Life On Bachelor Of Science Nursing Students, Parker E. Intonato

Honors College Theses

Empathy is a skill that nurses and nursing students must use with their patients to provide high quality care and build rapport with patients. Although, the prolonged use of empathy has been shown to increase compassion fatigue in nurses and decrease quality of life. Empathy has been described as the ability to feel and understand what another is experiencing. Compassion fatigue can be described as the natural response of emotions and behaviors that occur after experiencing and suffering the traumatic experiences of others. The effects of compassion fatigue call into question quality of life (QOL) issues. Quality of life includes …

Behind The Therapy Door: What Is “Usual Care” Aphasia Therapy In Acute Stroke Management?, Emily Brogan, Erin Godecke, Natalie Ciccone

Research outputs 2014 to 2021

Background:

Usual care is the term used to describe everyday practice in the management of a client within a profession. The knowledge of the tasks used in therapy and key therapeutic processes used within these treatments, provides critical information about if and how the therapy works. The Very Early Rehabilitation in SpEech Randomised Controlled Trial (VERSE RCT) had three arms with therapists within the intensive Usual Care-Plus arm (UC-Plus) providing daily direct aphasia therapy at their discretion for 20 sessions.

Aims:

To describe usual care aphasia treatment provided in the Usual Care-Plus arm of VERSE RCT.

Methods and Procedures:

One …

Tfeb Regulates Murine Liver Cell Fate During Development And Regeneration, Nunzia Pastore, Tuong Huynh, Niculin J Herz, Alessia Calcagni', Tiemo J Klisch, Lorenzo Brunetti, Kangho Ho Kim, Marco De Giorgi, Ayrea Hurley, Annamaria Carissimo, Margherita Mutarelli, Niya Aleksieva, Luca D'Orsi, William R Lagor, David D Moore, Carmine Settembre, Milton J Finegold, Stuart J Forbes, Andrea Ballabio

Faculty, Staff and Students Publications

It is well established that pluripotent stem cells in fetal and postnatal liver (LPCs) can differentiate into both hepatocytes and cholangiocytes. However, the signaling pathways implicated in the differentiation of LPCs are still incompletely understood. Transcription Factor EB (TFEB), a master regulator of lysosomal biogenesis and autophagy, is known to be involved in osteoblast and myeloid differentiation, but its role in lineage commitment in the liver has not been investigated. Here we show that during development and upon regeneration TFEB drives the differentiation status of murine LPCs into the progenitor/cholangiocyte lineage while inhibiting hepatocyte differentiation. Genetic interaction studies show that …

2020-05-17_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Promising Practices For Boating Safety Initiatives That Target Indigenous Peoples In New Zealand, Australia, The United States Of America, And Canada, Mitchell Crozier, Audrey R. Giles

International Journal of Aquatic Research and Education

Boating-related incidents are responsible for a significant number of the drowning fatalities that occur within Indigenous communities in New Zealand, Australia, the USA, and Canada. The aim of this paper was to identify promising practices for boating safety initiatives that target Indigenous peoples within these countries and evaluate past and ongoing boating safety initiatives delivered to/with Indigenous peoples within these countries to suggest the ways in which they – or programs that follow them - may be more effective. Based upon evidence from previous research, boating safety initiatives that target Indigenous peoples in New Zealand, Australia, the USA, and Canada …

Medical School Watercooler Newsletter - May 17, 2020, Lindsey Lyle

Watercooler Newsletter

This is the May 17, 2020 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA College of Medicine honors class of 2020

Surgery faculty member recognized for excellence in medical education

The Last Mile, Michael Hammond

Reflections, Poetry, Photos, and other Writings

My desire was to encourage the community as we head into Finals Week.

2020-05-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-05-17_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

An Assessment Of Human Interaction And Spending Behavior Amidst Corona Virus In The United Arab Emirates (Issue 6, 17 May 2020), Ahmed Almurshidi, Robert Bridi, Naeema Al Hosani

Covid19 Newsletters

No abstract provided.

2020-05-17_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was captured from the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_99207---,00.html.

The website contained the table Count of Confirmed COVID-19 Cases by Date of Onset , sorted by Michigan Preparedness Region. It also contained 18 charts, including the count of confirmed Covid-19 cases by date of onset in the state overall as well as in each preparedness region,and the normalized rate of Covid-19 cases per 1,000,000 residents in both the state and in each preparedness region.

2020-05-16/17 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Mari Anixter, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Timothy Campbell, Alexandra Yingling, Cristian Bologa, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

Only 1 case in NM state prisons. NM case count. NM travel warning. NM web-based recovery reporting system. NM Mask Madness Tournament. Face covering in ABQ. NM graduate medical program funding. ABQ Memorial Day cancellation. NM affordable housing funding. Taos farmers market drive through opening. US correctional facility cases. Social distancing works. Dogs sniffing out COVID-19. Germany's soccer league to restart. Mask effectiveness. Mask comfort w/cardboard cutout. Ammonium cleaning ineffective. CDC contact tracing guidance. Spanish immunity. CDC epidemic intelligence fellowship. Speaking transmits virus. Decontaminating workers. CDC advisory for children. Addressing ER fears. Indoor presymptomatic virus transfer. Virus transmission …