Medicine and Health Sciences Commons^™

Dtigems+: Drug-Target Interaction Prediction Using Graph Embedding, Graph Mining, And Similarity-Based Techniques., Maha A Thafar, Rawan S Olayan, Haitham Ashoor, Somayah Albaradei, Vladimir B Bajic, Xin Gao, Takashi Gojobori, Magbubah Essack

Faculty Research 2020

In silico prediction of drug-target interactions is a critical phase in the sustainable drug development process, especially when the research focus is to capitalize on the repositioning of existing drugs. However, developing such computational methods is not an easy task, but is much needed, as current methods that predict potential drug-target interactions suffer from high false-positive rates. Here we introduce DTiGEMS+, a computational method that predicts Drug-Target interactions using Graph Embedding, graph Mining, and Similarity-based techniques. DTiGEMS+ combines similarity-based as well as feature-based approaches, and models the identification of novel drug-target interactions as a link prediction problem in a heterogeneous …

Barriers To Colorectal Cancer Screening In Adults: An Integrative Review, Julie Sanger

Nursing Masters Papers

Colorectal Cancer (CRC) is the third leading cause of death among American men and women. Colorectal cancer is a preventable cancer, with CRC screening recommended from the age of 50. The percentage of people who complete the recommended CRC screening is low. Individuals throughout the United States (US) are rarely offered the opportunity to discuss screening options with their provider and may never complete CRC screening due to multiple barriers. The purpose of this scholarly integrative review is to explore the reasons individuals are not completing CRC screening, including those related to different US populations, and discuss interventions that can …

Benefits Of Palliative Care In The Intensive Care Unit, Stephen Swenson, Stephen M. Swenson

Nursing Masters Papers

Abstract

The use of palliative care is often overlooked until the terminal phase of serious illness when life-prolonging interventions are deemed futile and death is considered imminent.

Alongside the well regarded Clinical Practice Guidelines for Quality Palliative Care (National Coalition for Hospice and Palliative Care, 2018), numerous critical care societies including the American Association of Critical-Care Nurses (Medina & Puntillo, 2006), American College of Critical Care Medicine (Davidson et al., 2008), American College of Chest Physicians (Selecky et al., 2005), American College of Surgeons (2017), and the American Thoracic Society (Lanken et al., 2007) have each published individual policies highlighting …

Active Deep Learning Method To Automate Unbiased Stereology Cell Counting, Saeed Alahmari

USF Tampa Graduate Theses and Dissertations

Cell quantification in histopathology images plays a significant role in understanding and diagnosing diseases such as cancer and Alzheimers. The gold-standard for quantifying cells in tissue sections is the unbiased stereology approach. Unfortunately, in unbiased stereology current practices rely on a well-trained human to manually count hundreds of cells in microscopy images. However, this human-based manual approach is time-consuming, labor-intensive, subject to human errors, recognition bias, fatigue, variable training, poor reproducibility, and inter-observer error. Thus, the lack of high-throughput technology for automating unbiased stereology analyses remains a major obstacle to further progress in a wide range of neuroscience and cancer …

2020-06-29_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

Use Of National Consumer Survey Data To Explore Perceptions Of Complementary And Alternative Medicine, Alina Cernasev, Basma Gomaa, Keri Hager, Jon C. Schommer, Lawrence B. Brown

Pharmacy Faculty Articles and Research

Background: Although Complementary and Alternative Medicine (CAM) has been the standard of therapy in Asia for centuries, it started receiving more attention in the U.S. in the last three decades.

Objectives: The primary study objective was to explore individuals' perspectives of CAM. A secondary objective was to describe individuals' perceptions of pharmacists’ roles in facilitating their use of these services and products.

Methods: Data were obtained from the 2015 and 2016 National Consumer Surveys on the Medication Experience and Pharmacist Roles. Data were collected from adults residing in the United States via on-line, self-administered surveys coordinated by …

How Much Can Mexican Healthcare Providers Learn About Breastfeeding Through A Semi-Virtual Training? A Propensity Score Matching Analysis, Mireya Vilar-Compte, Rafael Pérez-Escamilla, Meztli Moncada, Diana Flores

Department of Public Health Scholarship and Creative Works

Background: Mexico has shown a worrisome decrease in breastfeeding indicators, especially in the lowest socioeconomic level. Improving breastfeeding protection, promotion, and support services through workforce development is a key area of intervention. The objective of this study is to assess the influence on breastfeeding knowledge and abilities of a semi-virtual training for primary healthcare providers assisting beneficiaries of PROSPERA in Mexico, which is one of the largest conditional cash-transfer programs in the world. Methods: Two independent cross-sectional samples of healthcare providers were drawn at baseline and post-intervention in three states of Mexico. Baseline data were collected among primary physicians, registered …

Assisted Living Facilities In Florida: Examining The Factors Associated With Entries, Closure, And Licensure Change, Joseph W. June

USF Tampa Graduate Theses and Dissertations

Assisted living facilities (ALFs) have become a large provider of long-term care in the United States. Their expansion has been met with interest from older adults who desire to be independent yet receive some services and from state legislators who recently have attempted to increase access. Studies in long-term care have focused extensively on nursing homes, but recent research has examined the effects of ALFs on the long-term care market. Research has been lacking in understanding the unique markets of ALFs. Describing themselves as “communities” and offering multiple options for housing, ALFs have targeted independent and wealthier older adults who …

College Of Health Professions News, Georgia Southern University

College of Health Professions: News & Publications (2012-2023)

• Georgia Southern students organize community health fairs in Chatham County

Timely Diagnosis And Staging Of Non-Alcoholic Fatty Liver Disease Using Transient Elastography And Clinical Parameters., Christine Shieh, Dina L. Halegoua-De Marzio, Matthew L. Hung, Jonathan M. Fenkel, Steven K. Herrine

Division of Gastroenterology and Hepatology Faculty Papers

Background and Aim: There is no standardized guideline to screen, image, or refer patients with non-alcoholic fatty liver disease (NAFLD) to a specialist. In this study, we used transient elastography (TE) to examine the fibrosis stages at which patients are first diagnosed with NAFLD. Subsequently, we analyzed metabolic markers to establish cut-offs beyond which noninvasive imaging should be considered to confirm NAFLD/non-alcoholic steatohepatitis fibrosis in patients.

Methods: Charts spanning July 2015-April 2018 for 116 NAFLD patients who had TE performed were reviewed. Univariate and multivariate analysis of metabolic markers was conducted.

Results: At the first hepatology visit, TE showed 73% …

Increased Covid-19 Risk For Adults With Intellectual And/Or Developmental Disability Living In Residential Group Homes, Scott D. Landes

Population Health Research Brief Series

Adults with intellectual and/or developmental disability living in group homes in New York are at higher risk of severe COVID-19 outcomes, including death.

Female Genital Mutilation/Cutting: A Review Of Laws And Policies In Kenya And Nigeria, Samuel Kimani, Otibho Obianwu

Reproductive Health

Female genital mutilation/cutting (FGM/C) is a cultural practice that has health and human rights impacts on girls and women. The health sector has responsibility for prevention and response to provision of care services to women/girls with FGM/C-related complications. The mandate for the health sector response to FGM/C is anchored in nationwide or sector-specific legal/policy instruments. Kenya and Nigeria have ratified global legal/policy instruments and adopted WHO guidelines/tools for the prevention and management of FGM/C. The extent to which existing legal/policy documents in these two countries address prevention and response to management of FGM/C has been unclear. A desk review was …

Appendices—Female Genital Mutilation/Cutting: A Review Of Laws And Policies In Kenya And Nigeria, Samuel Kimani, Otibho Obianwu

Reproductive Health

This document contains Appendices to “Female Genital Mutilation/Cutting: A Review of Laws and Policies in Kenya and Nigeria.” Appendix 1 contains two tables: “Components of Kenyan Laws Related to FGM/C Prevention and Management,” and “Components of Nigerian Laws Related to FGM/C Prevention and Management.” Appendix 2 contains seven tables: “Components Relevant to Health Sector Response to Prevention and Management of FGM/C in Kenyan Policies,” “Components Relevant to Health Sector Response to Prevention and Management of FGM/C in Nigerian Policies,” “Components Relevant to Health Sector Response to Prevention and Management of FGM/C in the Kenyan Plans of Action,” “Components Relevant to …

The Roles Of Primary Cilia In Cardiovascular Diseases And Cancer, Maha Jamal

Pharmaceutical Sciences (PhD) Dissertations

Primary cilia are sensory organelles present in most mammalian cell types and regulate cell cycle and signaling pathways. Biochemical and molecular dysfunctions of primary cilia are associated with a wide range of diseases, including cancer, ciliopathies polycystic kidney disease (PKD, liver disorders, mental retardation, and obesity to cardiovascular diseases. Dysfunction in endothelial cilia contributes to aberrant fluid-sensing and results in vascular disorders, such as hypertension, aneurysm, and atherosclerosis. In this dissertation, the most recent outcomes on the roles of endothelial primary cilia within vascular biology have been summarized. Moreover, we evaluate the correlation between cilia formation or length and cell …

Trends In Cancer Prevalence In Punjab, Pakistan: A Systematic Study From 2010 To 2016, Sana Hafeez, Asmat Mahmood, Rizwan Ullah Khan, Naila Malkani

Journal of Bioresource Management

Cancer is the second leading cause of death globally. However, in Pakistan, in the absence of a national cancer registry, it is difficult to predict the current status of cancer incidence. Therefore, a need was felt to design a study that can give a depiction of the prevalence of common cancer types and their relevance to the local population in the absence of a proper cancer registry system. In view of this, data was collected from 2010 to 2016 for breast, prostate, head and neck, cervical and colorectal cancer from the cancer hospitals and centres located all over Punjab, Pakistan. …

Preservation Of Medical Information In Healthcare Facilities In Delta State, Nigeria: A Survey, Isaac E. Anyira

Library Philosophy and Practice (e-journal)

This study surveyed healthcare facilities in Delta State, Nigeria in order to discover the major threats to medical records, to examine the strategies and methods of preserving medical information , and to examine the challenges militating against effective preservation of medical records in Delta State. The concepts of medical records and preservation of records were reviewed in literature. The survey method was used for the study. Medical staff members who are involved in handling health records in selected health facilities in Delta State were the target for this study. The questionnaire was the instrument used for data collection. The instrument …

Developing Alternatives To Protect Domestic Sheep From Predation In South Africa, David L. Bergman, Nico L. Avenant, Michael J. Bodenchuk, Eddie Steenkamp

United States Department of Agriculture Wildlife Services: Staff Publications

South Africa has approximately 8,000 commercial small livestock farms and 5,800 communal/subsistence farmers throughout the country. Reported rates of small livestock loss to predation range from 3-13% and 0.5-19% from communal farming areas. A range of predators exist on the African continent, but in southern Africa major livestock losses are primarily due to black-backed jackal and caracal. South Africans have been managing caracals and jackals for over 300 years with no elimination of predation. During the aforementioned time frame, producers have used and/or developed a number of techniques including lethal, nonlethal, and integrated predator damage management to address predation losses. …

No More “Social Distancing” But Practice Physical Separation, Debasree Das Gupta, David W. S. Wong

Kinesiology and Health Science Faculty Publications

Though not a new term, “social distancing” exploded onto the global stage as an expression to publicize the only means currently available to control the transmission of COVID-19. This term is increasingly being adopted and translated into the vernacular to inform and guide public behavior in most, if not all, countries around the world. However, any effective global response requires direct and unambiguous communication and sharing of ideas across communities with different cultural backgrounds as well as between researchers and responders across the disciplinary spectrum. Unfortunately, social distancing is a misnomer. The current use of social distancing – separating ourselves …

Applied Behavior Analysis For The Treatment Of Autism: A Systematic Review Of Assistive Technologies, Fábio Junior Alves, Emerson Assis De Carvalho, Juliana Aguilar, Lucelmo Lacerda De Brito, Guilherme Sousa Bastos

Special Education and Rehabilitation Counseling Student Research

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that may lead to significant impairment in social communication, repetitive patterns of behavior, and possible fixed and restricted interests. Applied Behavior Analysis (ABA) is a well-supported and evidence-based treatment for the delays attributed to ASD. Assistive technologies, such as gamification, software apps, computer-based training (Web), and robotics; provide a standardized method of implementing ABA techniques. This review provides a synthesis of the main characteristics of these technologies. The assessed proposals focused on technologies such as Distributed Systems, Image Processing, Gamification, and Robotics. The primary objectives of these tools sought to improve social …

Indicators Of Mild Cognitive Impairment Associated With Language Processing And Production, Diana Julbe-Delgado

USF Tampa Graduate Theses and Dissertations

The research purpose of the present study was to (1) examine cognitive-linguistic features related to processing and production across a series of tasks that are representative of everyday discourse and (2) compare older adults with and without mild cognitive impairment (MCI) across linguistic features. Twenty-seven participants, including 12 individuals with- and 15 individuals without MCI, were enrolled from a larger study (Hudak et al., 2019). Cognitive status was initially assessed as part of the larger study using the Montreal Cognitive Assessment (MoCA; Nasreddine et al., 2005). Participants who scored ≤ 25 on the MoCA received a standardized neuropsychological evaluation and …

Prevalence, Incidence, And Clearance Of Human Papillomavirus Types Covered By Current Vaccines In Men With Human Immunodeficiency Virus In The Sun Study, Pragna Patel, Tim Bush, Lois Conley, Elizabeth R Unger, Teresa M Darragh, Keith Henry, Gerome Escota, John T Brooks, Erna Milunka Kojic

2020-Current year OA Pubs

BACKGROUND: High-risk anal human papillomavirus (HPV) infection is prevalent among men living with human immunodeficiency virus (HIV); the association between 9-valent (9v) high-risk HPV (HR-HPV) vaccine types and abnormal cytology has not been well characterized.

METHODS: We followed a prospective cohort study of persons with HIV at 7 HIV clinics in 4 US cities from March 2004 through June 2012. Annually, providers collected separate anal swabs for HPV detection and cytopathologic examination. Among men, we examined prevalence, incidence, and clearance of 9v HR-HPV vaccine types, compared with other HR types, and associations with abnormal cytology to assess potential vaccine impact. …

Latina Daughters And Their Caregiving Roles, Denise A. Longoria, Nelda Rodriguez, John M. Gonzalez, Romeo Escobar

School of Social Work Faculty Publications

Responsibilities and cultural expectations can be somewhat different for Latino males and females. In general, males are expected to be more independent and dominant while females are expected to be more nurturing [1, 2]. Similar to other populations, caregiving for elderly relatives has traditionally been a role adopted by women in Latino cultures [3]. Furthermore, first-born or oldest Latinas are sometimes expected to take on the role of caregiver with younger siblings and/or aging parents [4]. McDermott and Mendez-Luck [5] found that this caregiving role was often cultivated at an early age through a continuous, formal and informal socialization process …

Medical School Watercooler Newsletter - June 28, 2020, Lindsey Lyle

Watercooler Newsletter

This is the June 28, 2020 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

What’s ‘universal masking’ at USA Health?

Conference on Mental Health set for July 29

2020-06-28_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change as facilities correct …

2020-06-28_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of care (POC) tests, look for current infection. Serology (antibody) tests are used to look for the possibility of previous infection.
Source: Michigan Disease Surveillance System (MDSS) and Vital Records

The website contained the tables …

Aged-Structured Modeling Of Covid-19 Pandemic In Usa, Uae And Algeria (Issue 14, 28 June 2020), Abdessamad Tridane Dr., Soufiane Bentout,, Salih Djilali, Tarik Mohammed

Covid19 Newsletters

No abstract provided.

2020-06-26/27/28 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Mala Htun, Crisitian Bologna, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM Highlights: State fair cancelled. Phase 2 reopening stalls. Fewer New Mexicans staying home. ABQ July 4 celebration plan. NM case update. US Highlights: Family members infected following surprise birthday party. New cases spike in Texas due to early reopening of bars. International Highlights: 50% in Austria ski resort have antibodies. Economics, Workforce, Supply Chain, PPE: Why people do not wear masks. Mask filtration efficiencies compared. Masks worn incorrectly. Ultraviolet-based biophotonic technologies. Improved mask designs. Mask wearing controversy. Epidemiology Highlights: Contamination through air flow paths. Contamination of wastewater circulation. Healthcare Policy Recommendations: Moralizing COVID-19 mitigation practices contributes to …

2020-06-28_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-06-28_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Electrochemical Evaluation Of A Multi-Site Clinical Depth Recording Electrode For Monitoring Cerebral Tissue Oxygen, Ana Ledo, Eliana Fernandes, Jorge E. Quintero, Greg A. Gerhardt, Rui M. Barbosa

Neurosurgery Faculty Publications

The intracranial measurement of local cerebral tissue oxygen levels—PbtO₂—has become a useful tool for the critical care unit to investigate severe trauma and ischemia injury in patients. Our preliminary work in animal models supports the hypothesis that multi-site depth electrode recording of PbtO₂ may give surgeons and critical care providers needed information about brain viability and the capacity for better recovery. Here, we present a surface morphology characterization and an electrochemical evaluation of the analytical properties toward oxygen detection of an FDA-approved, commercially available, clinical grade depth recording electrode comprising 12 Pt recording contacts. We found that …