Medicine and Health Sciences Commons^™

Differential Effects Of Buprenorphine/Naloxone Vs. Methadone On Quality Of Life Over Time: A Subset Of The Bravo Study (Buprenorphine To Improve Hiv Care Engagement And Outcomes: A Randomized Trial), Ali Mirzazadeh Javaheri

University Honors Theses

Health-related Quality of Life (QoL) is generally poorer in individuals with opioid use disorder (OUD) in comparison with those suffering from other chronic diseases. Little is known about the difference each buprenorphine/naloxone (BUP/NX) or methadone maintenance therapy (MMT) may make in the QoL for the HIV-infected people with OUD who are new to HIV care. The objective of this study is to evaluate the difference in the impact that BUP/NX and MMT treatment delivery models make on the QoL of the HIV-infected participants with OUD in Vietnam.

This study was a subset of the BRAVO study, buprenorphine to improve HIV …

New Mexico Children's Alliance Children's Advocacy Centers Needs Assessment, Theresa H. Cruz, Leona Woelk, Ivy Vitanzos Cervantes, Emily Guerra

Reports & Documents

No abstract provided.

Utstein Recommendation For Emergency Stroke Care, A. Rudd, P. Panagos, Et Al

2020-Current year OA Pubs

BACKGROUND: Recent advances in treatment for stroke give new possibilities for optimizing outcomes. To deliver these prehospital care needs to become more efficient.

AIM: To develop a framework to support improved delivery of prehospital care. The recommendations are aimed at clinicians involved in prehospital and emergency health systems who will often not be stroke specialists but need clear guidance as to how to develop and deliver safe and effective care for acute stroke patients.

METHODS: Building on the successful implementation program from the Global Resuscitation Alliance and the Resuscitation Academy, the Utstein methodology was used to define a generic chain …

Parenteral Lipids Shape Gut Bile Acid Pools And Microbiota Profiles In The Prevention Of Cholestasis In Preterm Pigs, Lee Call, Tiffany Molina, Barbara Stoll, Greg Guthrie, Shaji Chacko, Jogchum Plat, Jason Robinson, Sen Lin, Caitlin Vonderohe, Mahmoud Mohammad, Dennis Kunichoff, Stephanie Cruz, Patricio Lau, Muralidhar Premkumar, Jon Nielsen, Zhengfeng Fang, Oluyinka Olutoye, Thomas Thymann, Robert Britton, Per Sangild, Douglas Burrin

Children’s Nutrition Research Center Staff Publications

Multi-component lipid emulsions, rather than soy-oil emulsions, prevent cholestasis by an unknown mechanism. Here, we quantified liver function, bile acid pools, and gut microbial and metabolite profiles in premature parenterally fed pigs given a soy-oil lipid emulsion, Intralipid (IL), a multi component lipid emulsion, SMOFlipid (SMOF), a novel emulsion with a modified fatty-acid composition [experimental emulsion (EXP)], or a control enteral diet (ENT) for 22 days. We assayed serum cholestasis markers, measured total bile acid levels in plasma, liver, and gut contents, and analyzed colonic bacterial 16S rRNA gene sequences and metabolomic profiles. Serum cholestasis markers (i.e., bilirubin, bile acids, …

An Assessment Of Disinfection-Related Water Chemistry At Public Pools And Spas In Louisville, Kentucky, Thomas Gerding, Tim Wilder, Jason W. Marion

EKU Faculty and Staff Scholarship

The growth in the number of pools to more than 7.4 million in the U.S. has been accompanied by a rise in recreational water illnesses (RWIs). Effective pool management, though, can mitigate RWI risks. Inadequate management presumably occurs more frequently where training is less formalized and/or pool operation is a minor aspect of the job of the responsible pool manager(s). During summer 2018, weekly evaluations were performed at public venues in Louisville, Kentucky. Disinfectant levels and other items were monitored and compared with venue-specific (pool or spa) criteria. Among 1,312 venue surveys, 1,173 (89.4%) met criteria and 139 (10.6%) did …

Covid-19 Calls For Remote Reskilling And Retraining, C. Zou, W. Zhao, Keng Siau

Research Collection School Of Computing and Information Systems

Cui Zou, Wangchuchu Zhao, and Keng Siau respond directly to COVID-19 by framing the skills and training necessary to survive crises. The authors focus on the importance of helping organizations prepare beyond the current pandemic by teaching everyone how to use the technology tools -- and exploit the processes -- around remote working.

Ethical Considerations For Outpatient Behavioral Healthcare In North Texas, Carolyn B. Guillory

All Theses And Dissertations

The purpose of this Interpretative Phenomenological Analysis (IPA) study was to examine caregivers’ perceptions of practices for outpatient behavioral health care. Effort was made to gain insight into the components of ethical service delivery. Significant data on the providers’ perceptions of care was identified in literature reviews, though it was not the case for perspectives of consumers or caregivers. This population has been identified as one which is likely to experience unaffordable, fragmented, and confusing behavioral health systems (Baker, 2015). Attempts to inform research by addressing the quality of treatment was a focus. The Research Problem: Since 2016, the suicide …

Covid-19 Impact On Radiology Students’ Distance Learning, Mary Lee, Fahameda Hassan, Zoya Vinokur

Publications and Research

Distance learning (DL) is a teaching tool that offers education to students remotely in various locations (Ruiz, 2006). The increase in distance learning education is evident in all types of educational programs including those in Radiologic Sciences. DL education programs are expected to comply with all standards just as traditional programs are (Aaron, 2015). With a traditional class setting, knowledge is taught at a given time and day, which is structured in terms of course development and attendance. It does not factor in the domestic and familial responsibilities of the students outside the classroom walls. What happens when a pandemic …

Global Resting-State Functional Connectivity Of Neural Oscillations In Tinnitus With And Without Hearing Loss, Carly Demopoulos, Xuan Duong, Leighton B. Hinkley, Kamalini G. Ranasinghe, Danielle Mizuiri, Coleman Garrett, Susanne Honma, Jennifer Henderson-Sabes, Anne Findlay, Caroline Racine-Belkoura, Steven W. Cheung, Srikantan S. Nagarajan

All Faculty Scholarship

This study examined global resting-state functional connectivity of neural oscillations in individuals with chronic tinnitus and normal and impaired hearing. We tested the hypothesis that distinct neural oscillatory networks are engaged in tinnitus with and without hearing loss. In both tinnitus groups, with and without hearing loss, we identified multiple frequency band-dependent regions of increased and decreased global functional connectivity. We also found that the auditory domain of tinnitus severity, assayed by the Tinnitus Functional Index, was associated with global functional connectivity in both auditory and nonauditory regions. These findings provide candidate biomarkers to target and monitor treatments for tinnitus …

Post-Vaccination Pharyngeal-Cervical-Brachial Variant Of Guillain-Barré Syndrome, Funmilola T. Taiwo, Daniel E. Ezuduemoih, Philip Adebayo

Internal Medicine, East Africa

The pharyngeal-cervical-brachial (PCB) variant of Guillain-Barré syndrome (GBS) is very rare. It is characterized by weakness of the upper extremities associated with bulbar symptoms and facial diplegia. Documented cases were post-infectious, a post-vaccination occurrence has not been documented in the available literature. Even rarer is the occurrence of any variant of GBS following the mumps measles rubella (MMR) vaccine. The neurophysiological hallmark of PCB variant of GBS is a combination of myelinopathy and axonopathy, hence, its consideration as a subtype of the acute motor axonal neuropathy (AMAN) variant. It should be suspected in any case of acute-onset flaccid symmetrical weakness …

Effectiveness Of Multimodal Pain Therapy On Reducing Opioid Use In Surgical Geriatric Hip Fracture Patients., Kellie Girardot Msn, Rn, Lisa Hollister, Thein Zhu, Sarah Hoeppner, Dazar Opoku, Jason Heisler, Tabitha Bane Np

Nursing Publications, Posters, & Presentations

BACKGROUND: There is a need for appropriate pain control in the geriatric hip fracture population to prevent diminished function, increased mortality, and opioid dependence. Multimodal pain therapy is one method for reducing pain postoperatively while also decreasing opioid use in the geriatric hip fracture patient. This study aimed to determine whether multimodal pain therapy could decrease opioid use without increasing pain scores in surgical geriatric hip fracture patients.

METHODS: This was a before-and-after cohort study. The hospital implemented multimodal pain control order sets with a standardized pain regimen and performed retrospective chart review pre- and postorder set implementation for analysis. …

Coronary Artery Aneurysm In Kawasaki Disease., Achala Donuru, Maansi Parekh, Vinay V R Kandula, Sharon Gould

Department of Radiology Faculty Papers

A 3-year-old male presents to the emergency department with chief complaints of fever and vomiting. He had a positive rapid streptococcus throat test with cervical lymphadenopathy. The patient was started on antibiotics. On examination, there was diffuse erythematous macular rash on the chest. Laboratory tests revealed elevated white cell count and C-reactive protein. Electrocardiogram was notable for prolonged PR interval indicating 1^st degree atrioventricular block. Echocardiogram revealed ectasia of the right coronary artery (RCA). A presumptive diagnosis of Kawasaki disease was made and the patient was started on high-dose aspirin and intravenous immunoglobulins. Cardiac computed tomography angiography (CTA) showed …

The Pulmonary Venous Ridge Length To Stratify Stroke Risk In Atrial Fibrillation, Varun Singh, Joy Li, Mark Keroles, Daniel Frisch, Behzad B. Pavri, Baskaran Sundaram, Md, Jason Jacobson, Rajiv Kabadi

Department of Radiology Faculty Papers

Purpose of Study: To evaluate the left superior pulmonary venous ridge length (RL) and the left atrial appendage fractal dimension (LAA FD) as predictors of cardioembolic ischemic stroke (CVA) and transient ischemic attack (TIA) in patients with atrial fibrillation (AF).

Materials, Methods and Procedures: A multicenter, retrospective multicenter study was conducted on patients with AF who underwent cardiac CT prior to catheter ablation between 01/01/2010 and 12/31/2015. Patients were grouped by the presence or absence of prior CVA/TIA. Patients with mitral stenosis, prior mechanical aortic valve replacement, ascending aortic arch atheroma, highrisk patent foramen ovale, history of atrial septal repair …

Family Behaviors As Unchanging Obstacles In End-Of-Life Care: 16-Year Comparative Data, Renea L. Beckstrand, Jasmine B. Jenkins, Karlen E. Luthy, Janelle L. B. Macintosh

Faculty Publications

Background Critical care nurses routinely care for dying patients. Research on obstacles in providing end-of-life care has been conducted for more than 20 years, but change in such obstacles over time has not been examined.

Objective To determine whether the magnitude scores of obstacles and helpful behaviors regarding end-of-life care have changed over time.

Methods In this cross-sectional survey study, questionnaires were sent to 2000 randomly selected members of the American Association of Critical-Care Nurses. Obstacle and helpful behavior items were analyzed using mean magnitude scores. Current data were compared with data gathered in 1999.

Results Of the 2000 questionnaires …

Greater Fatigability And Motor Unit Discharge Variability In Human Type 2 Diabetes, Jonathon Senefeld, Kevin G. Keenan, Kevin S. Ryan, Sarah E. D'Astice, Francesco Negro, Sandra K. Hunter

Exercise Science Faculty Research and Publications

This study determined the discharge characteristics of motor units from two lower limb muscles before and after fatiguing exercise in people with type 2 diabetes (T2D) with no symptoms of polyneuropathy and activity-matched controls. Seventeen people with T2D (65.0 ± 5.6 years; 8 women) and 17 controls (63.6 ± 4.5 years; 8 women) performed: (a) intermittent, isometric contractions at 50% maximal voluntary isometric contraction (MVIC) sustained to failure with the ankle dorsiflexors, and (b) a dynamic fatiguing task (30% MVIC load) for 6 min with the knee extensors. Before and after the fatiguing tasks, motor unit characteristics (including coefficient of …

Using Genetic Diversity To Differentiate Mosquito Populations, Rachel Christine Malampy

Theses and Dissertations

Experiment 1: Little is known about Aedes aegypti females sharing oviposition sites. We examined four different oviposition sites in McAllen, TX. A mitochondrial gene was used to analyze the variation within the oviposition site to understand how many egg-laying females are sharing oviposition sites. These results will aid in the understanding of Aedes. aegypti oviposition behavior and contribute to more effective mosquito control techniques.

Experiment 2: Mosquito flight patterns and movement from habitat to habitat can drastically influence the spread of diseases. The anthropophilic Aedes aegypti mosquito has historically been identified as having a very limited flight range. Studies also …

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 69, Issue 2, Summer 2020

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• A Message from the President Facing Crises with Creativity
• Dean’s Column Difficult Times Define Us
• Jefferson COVID Stories
• Reflections from the Frontlines
• One Step of Many White Coats for Black Lives Peaceful Protest at Jefferson
• Time Capsule Philadelphia 1918: The Flu Pandemic Hits Home
• A Message from Elizabeth A. Dale Helping the Heroes
• Discovery Combating COVID-19
• Heroes on the Sidelines Sidelined from Patient Care, SKMC Students Find Purpose in Volunteer Work
• From the Front Lines to Online SKMC Doesn’t Miss a Beat in Medical Education
• Navigating Uncharted Waters in Search of the Class of 2024
• You’ve Got …

Improving Nutrition And Immunity With Dry Chain And Integrated Pest Management Food Technologies In Lmics., Peetambar Dahal, Meghnath Dhimal, Krishna Belbase, Sundar Tiwari, John Groopman, Keith West, Bradley Pollock, Subodh Pyakurel, Ganga Acharya, Sunil Aryal, Yug Nath Ghimire, Manish Neupane, Rosina Poudel, Johan Van Ashbrouck, Keshavulu Kunusoth, Sarah De Saeger, Marthe De Boevre, Gokarna Gharti-Chhetri, Tek Bahadur Gurung, Kent J Bradford

Department of Medical Oncology Faculty Papers

No abstract provided.

Models For Small Area Estimation For Census Tracts, John R Logan, Cici Bauer, Jun Ke, Hongwei Xu, Fan Li

Faculty, Staff and Student Publications

This study examines issues of Small Area Estimation (SAE) that are raised by reliance on the American Community Survey (ACS), which reports tract-level data based on much smaller samples than the decennial census long-form that it replaced. We demonstrate the problem using a 100% transcription of microdata from the 1940 census. By drawing many samples from two major cities, we confirm a known pattern: random samples yield unbiased point estimates of means or proportions, but estimates based on smaller samples have larger average errors in measurement and greater risk of large error. Sampling variability also inflates estimates of measures of …

Editorial, Mamatha S. Pai Dr

Manipal Journal of Nursing and Health Sciences

No abstract provided.

Effectiveness Of Computer-Assisted Teaching Program On Knowledge And Practice Of Postnatal Mothers Regarding Newborn Care, Mallika M Ms, Shilaja K. G Ms

Manipal Journal of Nursing and Health Sciences

Introduction: The arrival of a newborn in a family is a complex and significant event. There will be a series of functional changes to prepare the newborn for the passage across the bridge between gestation, within and outside the womb. Lack of essential newborn care is one of the leading causes of neonatal morbidity and mortality. To prevent these problems, practices such as clean cord care, thermal regulation and initiating breastfeeding immediately after birth could play an essential role. The objective of the study is to determine the effectiveness of computerassisted teaching program on knowledge and practice of postnatal mothers …

Adjustment And Self-Esteem Among Novice B Sc. Nursing Students Of Udupi District, Ankur Tiwari Mr, Savitha Prabhu Ms, Ansuya

Manipal Journal of Nursing and Health Sciences

Background: Everyone makes a lot of adjustments to lead a good life. The atmosphere in college plays an important role in developing the self-esteem of the students. Objective: To find the correlation between adjustment and selfesteem among novice B.Sc. Nursing students. Methods: The study was conducted with 196 first year B.Sc. Nursing students using correlative study design. A convenient sampling technique was adopted. Socio-demographic proforma, adjustment assessment inventory and state self-esteem scale were used to collect the data. Results: The findings of the study revealed that among 196 students, 119 (60.7%) had a moderate adjustment, 50 (25.5%) had a good …

Knowledge Of Mental Health And Mental Illness Among Students Of Selected Health Professional Colleges, Henshaw Ekanem N S A Ms, Tessy Treesa Jose Dr, Asha K. Nayak Ms

Manipal Journal of Nursing and Health Sciences

Introduction: For the effective delivery of mental health care, knowledge and awareness regarding mental illness has to be increased in the general population. Mental health has to be a concern for all of us, rather than only for those who feel pain from a psychological disorder. Objective: To determine the level of knowledge of mental health and mental illness among students of selected health professional colleges. Methods: The research approach was quantitative and descriptive survey design was used. The population in this study comprised of 385 first year students of selected health professional colleges who were selected through convenience sampling. …

Effect Of Nesting On Selected Physiological Parameters Among Preterm Babies, Hima P. Das Ms, Sreeja G. Pillai Ms, Molykutty Joyichan

Manipal Journal of Nursing and Health Sciences

This study was conducted to evaluate the effect of nesting on selected physiological parameters among preterm babies admitted in NICU of Pariyaram Medical College Hospital, Kannur. Methods: This is a quasi-experimental study with pre-test post-test design carried out among the 60 preterm babies consecutively selected as per inclusion criteria and the data was collected by using proforma for assessing socio-demographic data and physiological parameters monitoring chart. Results: The findings revealed that there is a significant difference in axillary temperature, heart rate, respiratory rate, SPO2, capillary refill time and activity including behavioral status, global posture, global tone, sucking reflex and stress …

Electronic Surveillance Systems For Healthcare-Associated Infections (Hais): Prerequisite In Healthcare, Soumya Christabel Ms, Christopher Sudhaker Dr, Muralidhar Varma Dr

Manipal Journal of Nursing and Health Sciences

Abstract: The surveillance of HAI involves the systematic collation of HAI data, analysis and transformation into information and disseminating to those related who can take necessary action to combat HAI. HAIs pose a major problem today within healthcare. Detecting HAI poses the main challenge in healthcare. In the face of limited resources, surveillance in its traditional format is labour intensive. During the last few decades, healthcare-related infections impose a major burden on healthcare seekers. Conversely, with the use of information technology, substantial efforts have been made to improve the efficacy of HAI surveillance. This review highlights the progress made in …

Bilateral Hydronephrosis: A Case Report, Edlin Glane Mathias Ms, Vijay Kumar Dr, Sundeep P. T Dr

Manipal Journal of Nursing and Health Sciences

Hydronephrosis involves the dilatation of the renal pelvis, calyces and ureter. It develops secondary to urinary tract obstruction and leads to a build-up of backpressure in the urinary tract. It can affect unilateral or bilateral kidneys and is caused either by blocking urine flow to the bladder or the urine is leaking backward through the reflux. We report a case of a 9-year-old child inpatient in a paediatric surgical unit. A cystoscopy revealed that the bladder is distended and the bladder wall is thickened. The child was on oral medication and the child had a good prognosis and was discharged …

Prelimbic Input To Basolateral Amygdala Facilitates The Acquisition Of Trace Cued Fear Memory Under Weak Training Conditions, Adam Kirry, Robert C. Twining, Marieke R. Gilmartin

Biomedical Sciences Faculty Research and Publications

The ability to predict the occurrence of an aversive outcome based on available cues requires associative learning and plastic changes in the amygdala. When the predictive cue and aversive shock outcome are separated in time as in trace fear conditioning, additional circuitry is needed, including the prelimbic (PL) area of the prefrontal cortex. We have previously shown that neuronal firing in the PL during the trace interval separating the cue and shock is required for trace cued fear memory formation, but whether this mnemonic signal is conveyed to the amygdala is unknown. Here we show in males that silencing PL …

Recommendations: Putting An End To Child Labour In Pakistan!, Meesha Iqbal, Zafar Fatmi, Kausar S. Khan, Asaad Ahmed Nafees, Neelma Amjad

Community Health Sciences

Child labour is rampant in Pakistan since ages. Laws, policies, programmes and strategies to eliminate child labour have been in place with little gain. Implementation of laws and sustainability of programmes offer barriers to eliminate the menace. We recommend a new approach of regulating child labour as a strategy to eliminate it in the longer run. Model districts with drop-in-centres offering free education to the working children should be constructed. The key stakeholders should unite on a common platform to formulate guidelines defining the nature and duration of work for children in various sectors such that they have sufficient time …

Furrowed Tongue, Fatten Lip And Facial Droop, Philip Adebayo, Hanifa Mbithe

Internal Medicine, East Africa

No abstract provided.

Inspire : Vol 3, Issue 7, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Medicine at National and International Forums
• Tele ICU Initiatives- Providing Quality Care to COVID-19 Patients Across Pakistan
• Dapagliflozin; breakthrough in management of Heart Failure with & without Type-II Diabetes
• Pioneering; First-Ever ‘Virtual Annual Research Day’
• Featured Faculty: Dr Ali Sarwar Zubairi “Maintain a decent work-life balance and spend time with family particularly your parents”
• Publications