2020-09-30_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change as facilities correct …

2020-09-30_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Genetic Variant Effects On Gene Expression In Human Pancreatic Islets And Their Implications For T2d., Ana Viñuela, Arushi Varshney, Martijn Van De Bunt, Rashmi B Prasad, Olof Asplund, Amanda Bennett, Michael Boehnke, Andrew A Brown, Michael R Erdos, João Fadista, Ola Hansson, Gad Hatem, Cédric Howald, Apoorva K Iyengar, Paul Johnson, Ulrika Krus, Patrick E Macdonald, Anubha Mahajan, Jocelyn E Manning Fox, Narisu Narisu, Vibe Nylander, Peter Orchard, Nikolay Oskolkov, Nikolaos I Panousis, Anthony Payne, Michael L. Stitzel, Swarooparani Vadlamudi, Ryan Welch, Francis S Collins, Karen L Mohlke, Anna L Gloyn, Laura J Scott, Emmanouil T Dermitzakis, Leif Groop, Stephen C J Parker, Mark I Mccarthy

Faculty Research 2020

Most signals detected by genome-wide association studies map to non-coding sequence and their tissue-specific effects influence transcriptional regulation. However, key tissues and cell-types required for functional inference are absent from large-scale resources. Here we explore the relationship between genetic variants influencing predisposition to type 2 diabetes (T2D) and related glycemic traits, and human pancreatic islet transcription using data from 420 donors. We find: (a) 7741 cis-eQTLs in islets with a replication rate across 44 GTEx tissues between 40% and 73%; (b) marked overlap between islet cis-eQTL signals and active regulatory sequences in islets, with reduced eQTL effect size observed in …

Ultrasound-Guided Peripheral Vascular Catheterization In Pediatric Patients: A Narrative Review, Yoshinobu Nakayama, Jun Takeshita, Yasufumi Nakajima, Nobuaki Shime

Publications and Research

Peripheral vascular catheterization (PVC) in pediatric patients is technically challenging. Ultrasound guidance has gained the most interest in perioperative and intensive care fields because it visualizes the exact location of small target vessels and is less invasive than other techniques. There have been a growing number of studies related to ultrasound guidance for PVC with or without difficult access in pediatric patients, and most findings have demonstrated its superiority to other techniques. There are various ultrasound guidance approaches, and a comprehensive understanding of the basics, operator experience, and selection of appropriate techniques is required for the successful utilization of this …

Improving Nurse Knowledge And Comfort In Advance Care Planning, Hajrudina Brkic, Marisia Young

Nursing DNP Projects

Objectives: The purpose of this project was to increase nurses’ knowledge and comfort level regarding advance care planning (ACP) in patients with a diagnosis of heart failure (HF) in a clinical setting.

Methods: A quasi-experimental design was used with a pre-and-post test administered to nurses prior to the beginning of a four-hour interactive class and immediately following the class. The data was analyzed using a 5-point Likert scale and paired t-tests were used to determine statistical significance. Statistical significance was set at 0.05.

Results: Of the eight nurses who participated in the interactive course, seven were female, one …

Adakah Perubahan Kesintasan Karsinoma Sel Hati Di Indonesia?, Chyntia Olivia Maurine Jasirwan

Jurnal Penyakit Dalam Indonesia

No abstract provided.

The Association Between Degree Of Diabetic Peripheral Neuropathy With Ankle Brachial Index, Toe Brachial Index, And Transcutaneus Partial Oxygen Pressure In Patients With Type 2 Diabetes Mellitus, Taufik Rizkian Asir, Dono Antono, Em Yunir, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetic peripheral neuropathy (DPN) in the lower extremity caused by complications of diabetes in the microvascular which can damage nerve in the lower extremity. Then, it is necessary to be aware of the process of aterosclerosis elsewhere, both in the macro and microvascular arteries in the lower extremity. This study was conducted to assess the association of the degree of diabetic peripheral neuropathy assessed by Toronto clinical scoring system (TCSS) with the process of atherosclerosis in the blood vessels of the lower extremity, both macrovascular with ankle brachial index (ABI) and toe brachial index (TBI), as well as microvascular …

Liver Function And Treatment Modalities Are Predictors Of Survival In Patients With Hepatocellular Carcinoma, Irsan Hasan, Imelda Maria Loho, Cosmas Rinaldi Lesmana, Rino A. Gani

Jurnal Penyakit Dalam Indonesia

Introduction. Hepatocellular carcinoma (HCC) is a major health problem in Indonesia because most patients are diagnosed in late stages when curative treatment is no longer possible. The aim of this study is to evaluate one-year survival rate, prognostic factors, and treatment modalities of patients with hepatocellular carcinoma. Methods. A retrospective analysis was done in patients with HCC who were admitted to Cipto Mangunkusumo General Hospital (CMGH) between January 2013 and March 2014. Clinical parameters and treatment modalities were evaluated. Patients outcome at one-year of follow-up were recorded from medical records or patients were contacted by phone call. Survival curve was …

Factor Related To The Incidence Of Ascites In Chronic Kidney Disease Patients Undergoing Hemodialysis At Rsud Dr Moewardi Surakarta: A Cross Sectional Study, Felizia Alika Yusman, Ratih Tri Kusuma Dewi, Yusuf Ari Mashuri, Evi Nurhayatun, Maia Thalia Giani

Jurnal Penyakit Dalam Indonesia

Introduction. Chronic kidney disease (CKD) is a global health issue with continuously rising prevalence. Fluid overload is a frequent systemic complication which occurs in CKD patients undergoing hemodialysis (HD). One of clinical manifestation of fluid overload in HD patients is ascites. This study aimed to determine the factors related to the incidence of ascites in CKD patients undergoing hemodialysis. Methods. An observational analytic study with a cross-sectional approach was conducted at Dr. Moewardi Hospital, Surakarta from September until October 2019. The subjects were end-stage CKD patients undergoing HD. Subjects were selected by total sampling technique. Data were obtained from medical …

Five Year Survival Of Active Multiple Myeloma Patients Based On Durie-Salmon And International Myeloma Working Group 2003 Diagnostic Criteria, Sri Agustini Kurniawati, Ary Harryanto Reksodiputro, Tubagus Djumhana Atmakusuma

Jurnal Penyakit Dalam Indonesia

Introduction. Survival of active multiple myeloma (MM) patients is determined by early diagnosis and various prognostic factors. The development of MM diagnostic criteria from Durie-Salmon (DS) criteria to International Myeloma Working Group (IMWG) 2003 is an attempt to diagnose active MM earlier. However, due to limited resources, these diagnostic criteria cannot be fulfilled consistently in Indonesia. Based on this reason, it is necessary to know the proportion of MM based on DS and IMWG 2003 diagnostic criteria and also their impact on the survival of MM patients in Indonesia. Methods. This was a retrospective cohort study with survival analysis. Subjects …

Prognosic Factors Related To The Complete Hematologic Response (Chr) In 3 Months In Leukemia Granulositic Patients Administered With Imatinib Mesylate, Ikhwan Rinaldi, Arry H. Reksodiputro

Jurnal Penyakit Dalam Indonesia

Introduction. The complete hematologic response is an integral part to achieve the complete cytogenetic response target and the major molecular response of imatinib mesylate therapy, although it does not determine the prognosis. The complete hematologic response in Indonesia is lower than in the world (74% vs. 95%). Sixty percent of chronic myeloid leukemia patients in Indonesia were administered hydroxyurea before imatinib mesylate. Chronic myeloid leukaemia (CML) patients in Indonesia are younger than in other countries. This study aimed to determine what prognostic factors which affect the complete hematological response of chronic phase CML patients who received imatinib mesylate in Indonesia. …

The Association Between Academic-Induced Stress With An Incident Of Dyspepsia On Grade Xii Natural Science Majors At 81 Senior High School East Jakarta In 2019, Lamya Hisyam Tamimi, Ryan Herardi, Sri Wahyuningsih

Jurnal Penyakit Dalam Indonesia

Introduction. Dyspepsia is a group of symptoms that are assumed to have it’s source from the upper digestive tract. However, one of the main causes of dyspepsia in adolescent is psychosocial, including stress. Stress in adolescent are commonly academic-induced. This study was aimed to observe the association between the level of academic-induced stress with an incident of dyspepsia, particularly of students who are in grade XII and major in natural sciences. Methods. This cross sectional study was conducted at 81 Senior High School East Jakarta using educational stress scale for adolescents (ESSA) questionnaire dan Short form-Leeds to dyspepsia questionnare (SF-LDQ). …

2020-09-30_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Exogenous Cushing Syndrome: When Do We Get The Benefit Of Glucocorticoid Stress Dose?, Soebagijo Adi Soelistijo, Hendra Gunawan, Chandra Adi Irawan Primasatya, Audy Meutia Ariana, Sony Wibisono Mudjanarko, Agung Pranoto

Jurnal Penyakit Dalam Indonesia

Exogenous cushing syndrome is the most common cushing syndrome found in clinical practice. Its most frequent etiology is the adverse effect of glucocorticoid therapy found in clinical practice or in the form of traditional medicine. The clinical manifestations of exogenous cushing syndrome are similar to the spontaneous counterpart, albeit with the presence of glucocorticoid consumption. We present a case series of exogenous cushing syndrome due to traditional medicine and glucocorticoid consumption with opportunistic infection as its initial manifestation. The first case did not need glucocorticoid supplementation while it was initiated in the second case. Comprehensive management of exogenous cushing syndrome …

Importation Of Macrocyclic Lactone Resistant Cyathostomins On A Us Thoroughbred Farm, Martin K. Nielsen, M. Banahan, R. M. Kaplan

Maxwell H. Gluck Equine Research Center Faculty Publications

Anthelmintic resistance in equine cyathostomins is both widespread and highly prevalent in the benzimidazole and tetrahydropyrimidine classes; however, reports of resistance to macrocyclic lactone (ML) drugs are sparse and sporadic. This study reports a case of clear ML resistance in a group of Thoroughbred yearlings imported from Ireland to the US in 2019. Fecal egg count reduction (FECR) following ivermectin administered in February 2020 demonstrated 100% reduction in the US bred yearlings, but 93.5%, 70.5%, and 74.5% reduction in three groups of the imported yearlings. The two former groups were then retreated with ivermectin, yielding FECRs of 33.8% and 23.5%, …

Plasma Proteins That May Cause Parkinson’S Disease And Multiple Sclerosis: A Mendelian Randomization Study, Brigid A. Staley

Dissertations and Theses

Multiple sclerosis (MS) and Parkinson’s disease (PD) are progressively disabling neurologic disorders that profoundly affect quality of life and shorten life expectancy. There is no cure for either disease, and current treatments only alleviate symptoms and may cause serious side effects. The causes of MS and PD are not well understood. Previous epidemiologic studies have documented numerous environmental risk factors for both diseases. However, these studies are inherently prone to bias from confounding which may generate spurious results. The lack of unbiased evidence on environmental causes of MS and PD has been a critical barrier to fully understanding their pathophysiology. …

Midline Report: Accelerating Action To End Child Marriage In Bangladesh, Masuma Billah, Eashita Haque, Surojit Kundu, Md. Saddam Hossain, Momoe Makino, Sajeda Amin

Poverty, Gender, and Youth

This report describes results from the midline survey of Accelerating Action to End Child Marriage in Bangladesh. The objective of the program is to identify effective and scalable approaches to end child marriage by empowering girls and communities. To bring about social norms change, the program experiments with alternative means of community engagement that can be offered in conjunction with skills-development opportunities for adolescent girls. The program is being assessed in a multi-arm cluster randomized trial. This report explores the impact on the prevalence of child marriage in two districts of Bangladesh as well as on a range of other …

Aptamer-Conjugated Plga Nanoparticles For Delivery And Imaging Of Cancer Therapeutic Drugs, Maryam Hashemi, Azarmidokht Shamshiri, Majid Saeedi, Lobat Tayebi, Rezvan Yazdian-Robati

School of Dentistry Faculty Research and Publications

Most problems associated with chemotherapeutic agents involve non-specific cytotoxicity, low intratumoral accumulation and drug resistance. Targeted drug delivery systems (TDDS) based on nanoparticles (NPs) are a new strategy for better therapeutic efficiency, along with reduction of side effects commonly seen with cancer drugs. Poly (lactic-co-glycolic acid) (PLGA), as one of the furthest developed synthetic polymer, has gained significant attention because of excellent properties—including biodegradability and biocompatibility, controlled release of drug, protection of drug or gene from decomposition and ability to modify surface with targeting agents for both cancer diagnosis and therapy. Aptamers are single-stranded RNA or DNA that can fold …

The Correlation Between The Quality Of Work Life Against The Performance Of The Employees Of Ogan Ilir District General Hosiptal, South Sumatera In 2018, Herliyanti Yadi, Dumilah Ayuningtyas

Journal of Indonesian Health Policy and Administration

A favorable work environment will influence the quality of work life, would create quality human resources, and support the improvements in the quality of services. To discover the correlation betweem the quality of work life and the employees’ performance at Ogan Ilir District General Hospital, a study was performed in March-April 2018. The study was a cross sectional quantitative study on 315 civil servants and voluntary staff at the hospital. Univariate, bivariate, and multivariate analysis was performed using the chi-square and the double regression prediction/determinant model. We discovered that the quality of the work life at the hospital was lacking, …

Strategic Plan For The Development Of The Rs Bersalin Grha Mutiara In 2019-2023: Policy Implementation, Melsha Syarahhandi, Mieke Savitri

Journal of Indonesian Health Policy and Administration

This research discusses the Strategic Plan for the Development of the RS Bersalin Grha Mutiara in 2019-2023, using the theory of Strategic Planning to observe and evaluate external environmental opportunities and threats as well as the internal strengths and weaknesses of the hospital, to determine the right strategic plan. This study is a qualitative research using primary data, in-depth interviews with informants, observation and decision making with CDMG (Consensus Decision Making Group), and secondary data obtained from the BPS (Central Bureau of Statistics), Dinas Kesehatan Subang (District Health Office) Profile, Profile and Financial Report of RS Bersalin Grha Mutiara. From …

Economic Burden Bore By Patients And Families Because Of Stroke: Policy Assessment, Honesty Fadhilah, Vetty Yulianty Permanasari

Journal of Indonesian Health Policy and Administration

Stroke to this day is still a disease that causes a high disability. In the future, it will require a prohibitive cost so that it has an impact on the socio-economic consequences for patients and their families. The price is prohibitive so that the impact on socioeconomic implications for patients and their families. Because of that, the purpose of the study is to estimate the cause of the cost that causes an economic burden from a stroke. The method that is used is a content analysis by doing a further literature review from various sources, from journal to textbook from …

Essential Drug Management At Rsu Karsa Husada Batu: Policy Implementation, Setya Haksama

Journal of Indonesian Health Policy and Administration

Coordination in a hospital is a necessary process needed to reach the organization’s goals. One of the processes that need coordination among cross-functional units is the essential drug procurement. The essential drug in Karsa Husada Batu Public Hospital (RSU Karsa Husada Batu) was often out of stock condition in some specific kinds of drugs. The average of the essential drug out of stock between the year of 2017 until the first semester of 2018 reached 33,73%. This number was far from the ideal standard of 0% out of stock condition. This research was aimed to recommend better coordination of essential …

The Effects Of Meditation In College Students, Katherine Shelton

Student Theses and Dissertations

Research has been conducted on young student age groups (ages 13-18) and the effects that meditation elicits on anxiety, stress and academic performance, but that is where the age is capped (Beauchemin, Hutchins, & Patterson, 2008). The purpose of this study was to investigate the effects of meditation on a previously understudied age category: undergraduate college students ages 18-22. All participants had their age, gender, height, weight, body mass index, systolic blood pressure, diastolic blood pressure, and resting heart rate measured before and after the study, and completed a 19-Item Body-Image Questionnaire (Koleck, Brunchon-Schweitzer, Cousson-Gélie, Gilliard, & Quintard, 2002). Results …

The Role Of Continous Ambulatory Peritoneal Dialysis In Equity Of Kidney Replacement Therapy In Indonesia, Aida Lydia

Jurnal Penyakit Dalam Indonesia

With the increasing incidence of chronic kidney disease in Indonesia, an effective, sustainable and widely available kidney replacement therapy (KRT) is needed. PD is one of the available modalities that can meet those criteria. To date, out of the two existing types of PD, only continuous ambulatory peritoneal dialysis (CAPD) is available in our country. Studies showed that residual kidney function is preserved better in CAPD patients compared to HD patients. With the use of CAPD as KRT, patients can do dialysis independently. Hence, it can be solution to the limitations and the difficulty of reaching HD units especially in …

The Impact Of The Deficit Reduction Act Of 2005 On The Length Of Hospital Stay, Honamattie Dabydeen

Dissertations and Theses

ABSTRACT

Introduction

Hospital-acquired infections (HAIs) are the most common complications of hospital care in the United States, and at least 1 in 10 patients admitted to the hospital will develop one. These unnecessary complications lead to about 99,000 premature deaths per year and add approximately $35–$45 billion of direct costs. Most of the cost increase is due to increases in hospital length of stay (LOS). This study examines the effect of a federal policy change on LOS among people with an HAI using the Donabedian quality of health care model as a framework. Specifically, this study examines the effect of …

Physicians Caring For Physicians As Patients, Olivia Seecof, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Outline

• Introduction
• Application to family medicine
• Ethics
• Literature supported rewards & challenges
• Navigating the physician/physician-patient relationship
• Summary and questions

Objectives

• Critically examine the physician-physician patient relationship through evidence in the literature
• Use cases to reflect on personal experiences
• Learn how to apply new strategies to navigate the visit with a physician-patient

Effects Of Germline And Somatic Events In Candidate Brca-Like Genes On Breast-Tumor Signatures, Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo

Pharmacy Faculty Articles and Research

Mutations in BRCA1 and BRCA2 cause deficiencies in homologous recombination repair (HR), resulting in repair of DNA double-strand breaks by the alternative non-homologous end-joining pathway, which is more error prone. HR deficiency of breast tumors is important because it is associated with better responses to platinum salt therapies and PARP inhibitors. Among other consequences of HR deficiency are characteristic somatic-mutation signatures and gene-expression patterns. The term “BRCA-like” (or “BRCAness”) describes tumors that harbor an HR defect but have no detectable germline mutation in BRCA1 or BRCA2. A better understanding of the genes and molecular events associated with tumors being …

Assessing Time From Door-To-Antibiotic Administration For Adult Cancer Patients With Neutropenic Fever In The Emergency Department, Sarah Roy, Tina Magsarili

Books, Presentations, Posters, Etc.

No abstract provided.

Effects Of An 8-Week Resistance Training Intervention On Plantar Flexor Muscle Quality And Functional Capacity In Older Women: A Randomised Controlled Trial, Pedro Lopez, Brendan James Crosby, Bruna Patrícia Robetti, Douglas Jean Preussler Turella, Thaís Andréia Schepa Weber, Morgana Lima De Oliveira, Anderson Rech

Research outputs 2014 to 2021

The present study examined 8 weeks of resistance training and its effects on muscle quality measures, plantar flexor muscle strength, muscle thickness and functional capacity in older women. Moreover, we tested if changes in muscle quality were associated with functional capacity. Twenty-four older women (66.3 ± 5.8 years; 69.0 ± 3.0 kg; 25.3 ± 1.4 kg·m−2) were recruited to the study. After completion of the baseline assessment, participants were randomly assigned to either the resistance training (RET, n = 12) or an active control group (CTR, n = 12). Muscle quality was evaluated through muscle echo intensity (MQEI) and specific …

Postgraduate Nurse Education And The Implications For Nurse And Patient Outcomes: A Systematic Review, Ma'en Zaid Abu-Qamar, Caroline Vafeas, Beverley Ewens, Manonita Ghosh, Deborah Sundin

Research outputs 2014 to 2021

Objectives: To synthesise the current evidence of the implications of postgraduate nursing qualifications on patient and nurse outcomes.

Design: A systematic review.

Data sources: Primary research findings.

Review methods: A systematic search following PRISMA guidelines and the Joanna Briggs Institute's framework was conducted. A structured and comprehensive search of three electronic databases CINAHL, MEDLINE, PsychINFO, search engine Google Scholar, and a manual-search of reference lists was undertaken. The search was limited to articles in English between 2000 and 2019. The combined search yielded 3710 records. Search records were exported to EndNote X8 and duplicates were removed. Inclusion eligibility was assessed …