Medicine and Health Sciences Commons^™

Implementation And Sustainment Of A Statewide Telemedicine Diabetic Retinopathy Screening Network For Federally Designated Safety-Net Clinics, Ana Bastos De Carvalho, S. Lee Ware, Feitong Lei, Heather M. Bush, Robert Sprang, Eric B. Higgins

Ophthalmology and Visual Science Faculty Publications

CONTEXT: Diabetic retinopathy (DR) is the leading cause of incident blindness among working-age adults in the United States. Federally designated safety-net clinics (FDSC) often serve as point-of-contact for patients least likely to receive recommended DR screenings, creating opportunity for targeted interventions to increase screening access and compliance.

STUDY DESIGN AND METHODS: With such a goal, we implemented and assessed the longitudinal performance of an FDSC-based telemedicine DR screening (TDRS) network of 22 clinical sites providing nonmydriatic fundus photography with remote interpretation and reporting. Retrospective analysis of patient encounters between February 2014 and January 2019 was performed to assess rates of …

Take Care Of One Another, John J. Petillo

University Briefings & Virtual Events

We are living in anxious times: A pandemic. Financial crisis. Racial, social and political divisions. And, now election uncertainties on a national level. The collective impact of all these stressors impacts each one of us.

2020-11-04_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-11-04_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2020-11-04_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change …

2020-11-04_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Harmony Study: Pimavanserin Significantly Reduces Risk Of Relapse Of Dementia-Related Psychosis, Erin P. Foff, Jeffrey L. Cummings, Maria-Eugenia Soto-Martin, Pierre Tariot, Bradley Mcevoy, Srdjan Stankovic

Integrated Health Sciences Faculty Research

No abstract provided.

Dental Practice During Covid-19 Pandemic: Risks And Measures, Eman Kheir, Nada Hashim

International Arab Journal of Dentistry

In December 2019, the novel coronavirus was discovered for the first time in Wuhan, China. On the 9th of January 2020, following a fast progression of the infection, the World Health Organization announced the finding to be a novel coronavirus that was named SARS-CoV-2. Dentistry has a very special working environment that puts it on the top of the lists of hazardous professions. The inherent nature of dental procedures might represent a transmission path for the virus. The spread of the disease can be prevented by taking strict measures before, during and after each dental procedure. The aim of this …

The Long-Term Effects Of Japan’S Traumatic Experience In The Second World War And Its Implications For Peace In Northeast Asia, Eugen Koh, Tadashi Takeshima

New England Journal of Public Policy

This article is an introductory report on the work of a Japanese study group whose primary aim is peacemaking, which it seeks by promoting a greater understanding of the long-term effects of their country’s traumatic experience of the Second World War. The group does not adopt a position of victimhood but seeks to understand the full picture of Japan’s role in the war, including its role as perpetrator. We came together with the shared assumption that the country’s inability to take responsibility for its role of the war is inextricably tied to its own traumatization. If this assumption is true, …

Discovery Of Driver Non-Coding Splice-Site-Creating Mutations In Cancer., Song Cao, Daniel Cui Zhou, Clara Oh, Reyka G Jayasinghe, Yanyan Zhao, Christopher J Yoon, Matthew A Wyczalkowski, Matthew H Bailey, Terrence Tsou, Qingsong Gao, Andrew Malone, Sheila Reynolds, Ilya Shmulevich, Michael C Wendl, Feng Chen, Li Ding

Articles, Abstracts, and Reports

Non-coding mutations can create splice sites, however the true extent of how such somatic non-coding mutations affect RNA splicing are largely unexplored. Here we use the MiSplice pipeline to analyze 783 cancer cases with WGS data and 9494 cases with WES data, discovering 562 non-coding mutations that lead to splicing alterations. Notably, most of these mutations create new exons. Introns associated with new exon creation are significantly larger than the genome-wide average intron size. We find that some mutation-induced splicing alterations are located in genes important in tumorigenesis (ATRX, BCOR, CDKN2B, MAP3K1, MAP3K4, MDM2, SMAD4, STK11, TP53 etc.), often leading …

Wolfer Drug Store Collection, 1878-1884, Special Collections, Leonard H. Axe Library

Finding Aids

A collection of ledgers from Wolfer Drug Store in Yates Center during the 1870s-1880s.

Wolfer Drug Store was started by James M. Wolfer (c1852-?), the first drug store in Yates Center, Kansas and was the third store in the town. Yates Center, the county seat of Woodson County, was founded in 1875 and named after the original owner of the town site, Abner Yates. In 1880, the store was sold to Dr. Samuel Jewett Bacon (1847-1908) who operated the store until the early 1900s.

Acute Skeletal Muscle Wasting And Dysfunction Predict Physical Disability At Hospital Discharge In Patients With Critical Illness, Kirby P. Mayer, Melissa L. Thompson Bastin, Ashley A. Montgomery-Yates, Amy M. Pastva, Esther E. Dupont-Versteegden, Selina M. Parry, Peter E. Morris

Physical Therapy Faculty Publications

BACKGROUND: Patients surviving critical illness develop muscle weakness and impairments in physical function; however, the relationship between early skeletal muscle alterations and physical function at hospital discharge remains unclear. The primary purpose of this study was to determine whether changes in muscle size, strength and power assessed in the intensive care unit (ICU) predict physical function at hospital discharge.

METHODS: Study design is a single-center, prospective, observational study in patients admitted to the medicine or cardiothoracic ICU with diagnosis of sepsis or acute respiratory failure. Rectus femoris (RF) and tibialis anterior (TA) muscle ultrasound images were obtained day one of …

Association Of Metabolomic Biomarkers With Sleeve Gastrectomy Weight Loss Outcomes, Wendy Miller, Kathryn Ziegler, Stewart Graham, Michael Maddens, Matthew Sims

Articles

Background: Factors influencing weight loss variability following sleeve gastrectomy (SG) are not well understood. We evaluated the correlation of metabolomic biomarkers with weight loss outcomes. Methods: This prospective study evaluated the metabolomic profile of feces and serum prior to SG and three months post-SG, along with weight loss outcomes at three months post-SG (N=45). Serum and fecal samples were quantitatively profiled using a combination of 1H NMR and DI-LC-MS/MS (AbsoluteIDQ P180 kit (Biocrates, Innsbruck)). Results: Percent total weight loss (%TWL) for the lowest versus the highest weight loss tertiles (T1 vs T3) was 11.1 + 0.8% and 17.0 + 1.3%, …

Peripheral Iv Bundle, Alicia Hanna

Graduate Theses, Dissertations, and Capstones

Abstract

It is estimated that over 90% of hospitalized patients require IV access during their hospitalization. Peripheral IVs (PIVs), while less risky than central lines, are not without risk to the patients. Intravenous (IV) infiltration in pediatric patients is a very common complication associated with IV access, accounting for about 67% of IV catheter removals; a less common complication, but much more serious complication of a PIV can be a blood stream infection (BSI) which can account for up to 35% of BSIs seen in patients. BSIs are associated with increased length of stay, increased morbidity and can result in …

Intravenous Immune Globulin Uses In The Fetus And Neonate: A Review., Mahdi Alsaleem

Manuscripts, Articles, Book Chapters and Other Papers

Intravenous immune globulin (IVIG) is made after processing plasma from healthy donors. It is composed mainly of pooled immunoglobulin and has clinical evidence-based applications in adult and pediatric populations. Recently, several clinical applications have been proposed for managing conditions in the neonatal population, such as hemolytic disease of the newborn, treatment, and prophylaxis for sepsis in high-risk neonates, enterovirus parvovirus and COVID-19 related neonatal infections, fetal and neonatal immune-induced thrombocytopenia, neonatal hemochromatosis, neonatal Kawasaki disease, and some types of immunodeficiency. The dosing, mechanism of action, effectiveness, side effects, and adverse reactions of IVIG have been relatively well studied in adults …

The Role Of The Oncology Nurse Navigator In Establishing An Epic Workflow For Virtual Multidisciplinary Clinics During Covid Restrictions., Laura Beaupre Bsn, Ocn, Cbpn-Ic, Kathy Sevedge Rn, Ma, Aocn, Angela Miller Rn, Bsn, Ocn, Med, Alyssa Pauls Rn, Bsn, Ocn, Jane Zubia Rn, Ocn, Cbpn I-C, Raizalie Roman-Rosado Bsn, Ocn, Cmsrn, Martiza Y. Chicas Rn, Bsn, Ocn, Cynthia Smith Rn,Bsn, Ocn, Ma, Tracy L. Walczer Rn, Bsn, Ocn, Jeanne Kenna Rn, Ocn, Paul Torresson, Eileen Steirer

Patient Care Services / Nursing

No abstract provided.

Participant Retention In Trauma Intensive Care Unit (Icu) Follow-Up Studies: A Post-Hoc Analysis Of A Previous Scoping Review, Himanshu Rawal, Daniel L. Young, Roozbeh Nikooie, Awsse H. Al Ani, Lisa Aronson Friedman, Sumana Vasishta, Elliott R. Haut, Elizabeth Colantuoni, Dale M. Needham, Victor D. Dinglas

Physical Therapy Faculty Research

Background The study aimed to synthesize participant retention-related data for longitudinal follow-up studies of survivors from trauma intensive care units (ICUs). Methods Within a published scoping review evaluating ICU patient outcomes after hospital discharge, two screeners independently searched for trauma ICU survivorship studies. Results There were 11 trauma ICU follow-up studies, all of which were cohort studies. Twelve months (range: 1-60 months) was the most frequent follow-up time point for assessment (63% of studies). Retention rates ranged from 54% to 94% across time points and could not be calculated for two studies (18%). Pooled retention rates at 3, 6, and …

The Effect Of Hope On The Relationship Between Personal And Disease Characteristics And Anxiety And Depression In Adolescents And Young Adults With Cancer, Sharon B. Mcneil

USF Tampa Graduate Theses and Dissertations

Adolescents and young adults (AYAs) with cancer face physical, psychosocial, emotional, and developmental challenges that are unique to their age group. In facing the crisis of a cancer diagnosis, both social support and hope have been shown to be tools utilized by some AYAs. However, AYAs have higher rates of anxiety and depression than in older adults which may have an effect on their levels of hope.

This cross-sectional study examined the mechanistic effects of hope on the relationship between personal characteristics of age, gender, and social support, the disease characteristics of type of cancer and length of time since …

Coevolution, Dynamics And Allostery Conspire In Shaping Cooperative Binding And Signal Transmission Of The Sars-Cov-2 Spike Protein With Human Angiotensin-Converting Enzyme 2, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Binding to the host receptor is a critical initial step for the coronavirus SARS-CoV-2 spike protein to enter into target cells and trigger virus transmission. A detailed dynamic and energetic view of the binding mechanisms underlying virus entry is not fully understood and the consensus around the molecular origins behind binding preferences of SARS-CoV-2 for binding with the angiotensin-converting enzyme 2 (ACE2) host receptor is yet to be established. In this work, we performed a comprehensive computational investigation in which sequence analysis and modeling of coevolutionary networks are combined with atomistic molecular simulations and comparative binding free energy analysis of …

Spontaneous Improvement Of Levator Palpebrae Superioris Function After Traumatic Transection., Craig Czyz, Kyle Blair

Trauma and Acute Care Articles

Direct traumatic injury to the levator palpebrae superioris aponeurosis typically results in upper eyelid ptosis. The mechanisms can involve mechanical or neurogenic etiologies. Prompt surgical exploration and repair are required for restoration of normal function. In cases where prompt surgical intervention is not performed or the levator palpebrae superioris aponeurosis cannot be repaired, the restorative options are limited. The options are further restricted by concurrent ipsilateral frontalis paresis. This report details a spontaneous return of levator function nine months after complete traumatic transection of the levator palpebrae superioris aponeurosis complicated by concurrent ipsilateral frontalis paresis.

Genetics And Geography Of Leukocyte Telomere Length In Sub-Saharan Africans, Steven C Hunt, Michael A Province, Et Al.

2020-Current year OA Pubs

Leukocyte telomere length (LTL) might be causal in cardiovascular disease and major cancers. To elucidate the roles of genetics and geography in LTL variability across humans, we compared LTL measured in 1295 sub-Saharan Africans (SSAs) with 559 African-Americans (AAms) and 2464 European-Americans (EAms). LTL differed significantly across SSAs (P = 0.003), with the San from Botswana (with the oldest genomic ancestry) having the longest LTL and populations from Ethiopia having the shortest LTL. SSAs had significantly longer LTL than AAms [P = 6.5(e-16)] whose LTL was significantly longer than EAms [P = 2.5(e-7)]. Genetic variation in SSAs explained 52% of …

A Multisite Study Of A Breast Density Deep Learning Model For Full-Field Digital Mammography And Synthetic Mammography, Thomas P Matthews, Sadanand Singh, Brent Mombourquette, Jason Su, Meet P Shah, Stefano Pedemonte, Aaron Long, David Maffit, Jenny Gurney, Rodrigo Morales Hoil, Nikita Ghare, Douglas Smith, Stephen M Moore, Susan C Marks, Richard L Wahl

2020-Current year OA Pubs

PURPOSE: To develop a Breast Imaging Reporting and Data System (BI-RADS) breast density deep learning (DL) model in a multisite setting for synthetic two-dimensional mammographic (SM) images derived from digital breast tomosynthesis examinations by using full-field digital mammographic (FFDM) images and limited SM data.

MATERIALS AND METHODS: A DL model was trained to predict BI-RADS breast density by using FFDM images acquired from 2008 to 2017 (site 1: 57 492 patients, 187 627 examinations, 750 752 images) for this retrospective study. The FFDM model was evaluated by using SM datasets from two institutions (site 1: 3842 patients, 3866 examinations, 14 …

The Role Of Microbiologic Agents In The Progression Of The Atherosclerosis: A Comprehensive Review, Ahmet Karabulut

Journal of the Saudi Heart Association

Atherosclerosis is a leading cause of disability, morbidity and mortality in the world. Atherosclerosis is accepted as a chronic progressive inflammatory disease. The inflammatory cascade in the vascular wall is well-defined. However, the predictors and contributors of the inflammatory response in atherosclerosis are not completely understood. Systemic and local inflammation, which enhance the burden of inflammation in the vascular wall, have been proposed as risk factors for the progression of atherosclerosis. Infectious micro-organisms are one of the major triggering factors for local and systemic inflammation. In this review, we aimed to emphasize the linkage between micro-organisms and the progression of …

Understanding Orthostatic Intolerance And Exercise Programming For The Health And Fitness Practitioner, Deni Roller, Carley A. Shannon, Andrew T. Del Pozzi

Topics in Exercise Science and Kinesiology

• The purpose of this manuscript is to briefly review Orthostatic Intolerance (OI) and discuss proper exercise programming and progression guidelines for working with those affected by OI; a disorder associated with autonomic nervous system dysfunction, characterized by a difficulty standing upright.
• In order to do this, we performed a review of the published literature using google scholar and PubMed search engines.
• Evidence indicated that a light to moderate intensity aerobic exercise program would aid in improving orthostatic tolerance.
• Previous studies have indicated that progressive resistance training aids in mechanisms that are dysfunctional in OI such as blood volume increases and …

Clinician’S Corner Tooth Transposition: The Clinical Features And Management A Case Report, Emad Hussein

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Tooth transposition is a rare developmental dental anomaly of unknown etiology. It exhibits a clinical challenge due to the presence of 2 teeth in a narrow buccolingual thickness of bone that had interchanged in position; care should be taken to avoid root proximity during movement of the transposed teeth during orthodontic treatment. The acceptance of tooth transposition could be considered the safest method of treatment on the root structure and the surrounding periodontium of the transposed teeth. Correction of tooth transposition could be tried in cases of maxillary lateral incisor canine transposition to avoid adverse effects on esthetics.

Assessing Biobehavioral Effects Of Exposure To Traumatic Events In Palestinian Children, Mohammad Asia

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Background: A growing body of work suggests that exposure of children to the trauma of war threatens their physical and psychological development. Children exposed to such childhood adversity have an increased risk of developing mental health problems, including posttraumatic stress disorder (PTSD), emotional and behavioral problems, and psychobiological ailments. Methods: This pilot study used a descriptive cross-sectional design to explore the relationships among traumatic event exposure, child stress, and biological stress markers (salivary cortisol and salivary alpha-amylase) measured in a sample of 37 West Bank Palestinian children aged 10-12 years. Results: Findings revealed moderate correlations between perceived child stress scores …

Aminotrasferase (Tat) Gene Mutations Among Palestinian Tyrosinemia Type Ii Patients: An Extended Study, Hisham Darwish

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Tyrosinemia type II, known as Richner-Hanhart syndrome (RHS), is a rare autosomal recessive disorder caused by mutations in the tyrosine aminotransferase (TAT) gene characterized by painful palmoplantar hyperkeratosis, pseudo dendritic keratitis and variable mental retardation. Several various mutations have been reported so far in the gene. Although many clinical complications of patients from the Middle East were described, the molecular basis of the disease was limited to some Tunisian and Palestinian patients. Direct molecular analysis represents the optimum approach to identify new patients or carriers of mutations in prenatal diagnosis since TAT is not expressed in chorionic villi or amniocytes. …

A Comparative Study Of Coronary Risk Factors Between Urban And Rural Diabetics In Gaza Strip, Akram Al-Taher

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Background: Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Higher risk of coronary heart disease (CHD) is seen in DM patients who smoke, have lipid abnormalities and hypertension and are obese.
Aim: The aim of this study is to compare the lipid profile levels and other CHD risk factors among DM patients in an urban region (Gaza governorate) with those of the rural region (the eastern region of Khanyounis Governorate) of Gaza Strip. Methods: The study is cross-sectional and included 200 DM patients, aged 10-65 years, whose diabetes …

Evaluation Of The Lateral Flow Immunoassays And Electrochemiluminescent Technique For Detection Of Hepatitis B, Eidha Hameed

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Infection of hepatitis B virus (HBV) is the most common type of viral diseases worldwide; Hepatitis B surface antigen (HBsAg) is the principal target for laboratory tests to diagnose the HBV infection. Therefore, rapid tests for its diagnosis are less costly, and easy to perform and develop recently.

This study aimed to evaluate the reliability of lateral flow immunoassays (LFA) and electrochemiluminescent (ECL) technique for the detection of HBsAg in Hadhramout/Yemen.

A total of 85 serum samples were tested for HBsAg by ECL technique (cobas e 411) and three rapid LFA cassettes (INTEC, ACRO and HEALGEN). Sensitivity and specificity of …

Potential Consequences Of The Red Blood Cell Storage Lesion On Cardiac Electrophysiology, Marissa Reilly, Chantel D. Bruno, Tomas M. Prudencio, Nina Ciccarelli, Devon Guerrelli, Raj Nair, Manelle Ramadan, Naomi L C Luban, Nikki Gillum Posnack

Pediatrics Faculty Publications

No abstract provided.