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2020

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Full-Text Articles in Medicine and Health Sciences

2020-11-08_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services Nov 2020

2020-11-08_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …


Research Ethics: What Nurses Need To Know, Kathryn Schroeter Nov 2020

Research Ethics: What Nurses Need To Know, Kathryn Schroeter

College of Nursing Faculty Research and Publications

No abstract provided.


The Relationship Between Standing For Long Times And Appearance Of Varicose Vein Among Barber In Northern Districts / West Bank, Ziad Nasrallah Nov 2020

The Relationship Between Standing For Long Times And Appearance Of Varicose Vein Among Barber In Northern Districts / West Bank, Ziad Nasrallah

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

The aim of this study was to identify the relationship between standing for long time and physical ap-pearance of varicose vein among barbers, as well as the medical problems associated with long standing. A descriptive analytical design was used to test many demographic variables, namely age, weight, height, period of activity, and daily hours of standing. This was done with the help of a questionnaire that in-volved four domains with 32 questions. The samples included 195 barbers chosen from different cities (Jenin, Nablus and Tollkaram) in Northern West bank. We found that those who stand for long time are 75 …


A Critical Review Of The Abductor Pollicis Longus Electromyographic Activity, Hisham Arabkabeya Nov 2020

A Critical Review Of The Abductor Pollicis Longus Electromyographic Activity, Hisham Arabkabeya

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

The aim of this study was to review the current evidence of the abductor pollicis longus electromyographic activity during thumb movements. The author performed an electronic thorough search for EMBASE, MEDLINE, CINAHL, and Web of Knowledge articles. Nine pieces in particular were found to explore the electromyographic activity of the abductor pollicis longus during thumb functional and non-functional movements. Consistent results were noticed, all emphasizing the key role of abductor pollicis longus in stabilizing the thumb's carpometacarpal joint. All target studies provided useful information about the abductor pollicis longus electromyographic activity. However, none of them examined the relationship between abductor …


Microbial Load Of Touch Screen Mobile Phones Used By University Students And Healthcare Staff, Abdelraouf Elmanama Nov 2020

Microbial Load Of Touch Screen Mobile Phones Used By University Students And Healthcare Staff, Abdelraouf Elmanama

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Mobile phones have become an indispensable part of our lives. Though they offer plenty of advantages, they are prolific breeding grounds for infectious pathogens in communities and hospitals. The present study seeks to identify the counts and types of bacteria contaminating touch screen mobile phones (TSMP) used by students of the Islamic University-Gaza (IUG) and healthcare workers (HCWs) at Al-Shifa Hospital. It also tries to investigate the antimicrobial resistance profiles. A cross-sectional study was conducted from October 2013 to April 2014. Two hundred and fifty swab samples were collected: 100 IUG female students, 100 IUG male students and 50 from …


2020-11-07_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Nov 2020

2020-11-07_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …


Coronavirus Update 11-7-20, The Coronavirus Planning Team Nov 2020

Coronavirus Update 11-7-20, The Coronavirus Planning Team

University Briefings & Virtual Events

Everything went very well today both with the exit testing and with parents coming to pick up students who are choosing to finish up the semester from home.


Amniotic Fluid Embolism And The Possible Protective Effects Of Heterozygous Factor V Leiden: A Case Report, Sanela Andelija, Olga M. Colon-Mercado, Kevin Rivera Rodriguez, Jessica A. Young, Greg Den Haese Nov 2020

Amniotic Fluid Embolism And The Possible Protective Effects Of Heterozygous Factor V Leiden: A Case Report, Sanela Andelija, Olga M. Colon-Mercado, Kevin Rivera Rodriguez, Jessica A. Young, Greg Den Haese

OB-GYN

Background: Amniotic fluid embolism (AFE) is a rare and commonly fatal obstetric emergency theorized to trigger an inflammatory reaction much like the systemic inflammatory response syndrome (SIRS) of sepsis, leading to vascular constriction and coagulation. This often results in acute respiratory distress syndrome (ARDS), cardiopulmonary arrest, disseminated intravascular coagulation (DIC), and death. With similar theorized mechanisms, we suspect factors that may modify mortality in sepsis may also modify mortality in AFE. Specifically, we ask if alterations in the coagulation cascade of heterozygous Factor V Leiden mutation (FVL+/-) can decrease mortality as seen in studies with severe sepsis. The following case …


2020-11-07_Michigandaily_Covidmap, Michigan Department Of Health & Human Services Nov 2020

2020-11-07_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …


Diagnosis Of A Longitudinal Vaginal Septum And Possible Uterus Didelphys Secondary To Coital Injury With An Artificial Phallus, Lauren Sword, Olga Marie Colon-Mercado, James Baron, Mark Sanchez, Tiffany R. Tonismae, Nicole L. Plenty Nov 2020

Diagnosis Of A Longitudinal Vaginal Septum And Possible Uterus Didelphys Secondary To Coital Injury With An Artificial Phallus, Lauren Sword, Olga Marie Colon-Mercado, James Baron, Mark Sanchez, Tiffany R. Tonismae, Nicole L. Plenty

OB-GYN

See attached document for abstract.


Managing May-Thurner Syndrome And Associated Complications Throughout Pregnancy And Postpartum, Jessica A. Young, Stephen Zweibach, Nicole L. Plenty, Tiffany Tonismae Nov 2020

Managing May-Thurner Syndrome And Associated Complications Throughout Pregnancy And Postpartum, Jessica A. Young, Stephen Zweibach, Nicole L. Plenty, Tiffany Tonismae

OB-GYN

No abstract provided.


New Generation Vmat2 Inhibitors Induced Parkinsonism, Rani Priyanka Vasireddy, Brent Sokola, Zain Guduru Nov 2020

New Generation Vmat2 Inhibitors Induced Parkinsonism, Rani Priyanka Vasireddy, Brent Sokola, Zain Guduru

Neurology Faculty Publications

Highlights

  • Drug induced parkinsonism caused by valbenazine and deutetrabenazine.
  • Possible side effects of VMAT-2 inhibitors.
  • Valbenazine and deutetrabenazine can unmask underlying Parkinson’s Disease.


Relationship Of Spot Urine Oxalate To Creatinine Ratio And 24 Hours Urinary Oxalate Excretion In Patients With Urolithiasis, Syed Bilal Hashmi, Lena Jafri, Hafsa Majid, Jamsheer Jehangir Talati, Wajahat Aziz, Aysha Habib Khan Nov 2020

Relationship Of Spot Urine Oxalate To Creatinine Ratio And 24 Hours Urinary Oxalate Excretion In Patients With Urolithiasis, Syed Bilal Hashmi, Lena Jafri, Hafsa Majid, Jamsheer Jehangir Talati, Wajahat Aziz, Aysha Habib Khan

Department of Pathology and Laboratory Medicine

Background: The evaluation of 24 h urinary oxalate excretion is the gold standard for diagnosing hyperoxaluria in patients with recurrent urolithiasis. However, 24 h urine sample collection is cumbersome. Therefore we aim to see if oxalate to creatinine ratio in random urine sample can be used as an alternative.
Materials and methods: A cross-sectional study was conducted at Section of Chemical Pathology, Department of Pathology and Laboratory Medicine Aga Khan University Karachi from 1st February to December 31, 2019. A total of 62 adult patients, 18-60 years of age with history of kidney stones presenting to the clinical laboratory for …


Simulator-Based Ultrasound Training For Identification Of Endotracheal Tube Placement In A Neonatal Intensive Care Unit Using Point Of Care Ultrasound, Khushboo Qaim Ali, Sajid Bashir Soofi, Ali Shabbir Hussain, Uzair Ansari, Shaun Morris, Mark Oliver Tessaro, Shabina Ariff, Hasan Merali Nov 2020

Simulator-Based Ultrasound Training For Identification Of Endotracheal Tube Placement In A Neonatal Intensive Care Unit Using Point Of Care Ultrasound, Khushboo Qaim Ali, Sajid Bashir Soofi, Ali Shabbir Hussain, Uzair Ansari, Shaun Morris, Mark Oliver Tessaro, Shabina Ariff, Hasan Merali

Department of Paediatrics and Child Health

Background: Simulators are an extensively utilized teaching tool in clinical settings. Simulation enables learners to practice and improve their skills in a safe and controlled environment before using these skills on patients. We evaluated the effect of a training session utilizing a novel intubation ultrasound simulator on the accuracy of provider detection of tracheal versus esophageal neonatal endotracheal tube (ETT) placement using point-of-care ultrasound (POCUS). We also investigated whether the time to POCUS image interpretation decreased with repeated simulator attempts.
Methods: Sixty neonatal health care providers participated in a three-hour simulator-based training session in the neonatal intensive care unit (NICU) …


Loss Of Class Iii Phosphoinositide 3-Kinase Vps34 Results In Cone Degeneration, Ammaji Rajala, Feng He, Robert E Anderson, Theodore G Wensel, Raju V S Rajala Nov 2020

Loss Of Class Iii Phosphoinositide 3-Kinase Vps34 Results In Cone Degeneration, Ammaji Rajala, Feng He, Robert E Anderson, Theodore G Wensel, Raju V S Rajala

Faculty, Staff and Students Publications

The major pathway for the production of the low-abundance membrane lipid phosphatidylinositol 3-phosphate (PI(3)P) synthesis is catalyzed by class III phosphoinositide 3-kinase (PI3K) Vps34. The absence of Vps34 was previously found to disrupt autophagy and other membrane-trafficking pathways in some sensory neurons, but the roles of phosphatidylinositol 3-phosphate and Vps34 in cone photoreceptor cells have not previously been explored. We found that the deletion of Vps34 in neighboring rods in mouse retina did not disrupt cone function up to 8 weeks after birth, despite diminished rod function. Immunoblotting and lipid analysis of cones isolated from the cone-dominant retinas of the …


Covid-19 Response Team Update, November 6, 2020, University Of Northern Iowa Nov 2020

Covid-19 Response Team Update, November 6, 2020, University Of Northern Iowa

UNI Response to COVID-19

Provides an update on the infection rate on campus and a reminder to follow the mitigation efforts through the end of the fall semester.


2020-11-06_Michigandaily_Covidmap, Michigan Department Of Health & Human Services Nov 2020

2020-11-06_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …


Coronavirus Update 11-6-2020, The Coronavirus Planning Team Nov 2020

Coronavirus Update 11-6-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

Since we communicated with you yesterday, we have a total of 34 new positive COVID-19 cases—25 on campus and nine off campus. We are also still receiving results from this week’s random asymptomatic testing. Because of this continued spike, we are moving our alert status to red. This decision was made after careful deliberations and discussion with state and local health officials about how best to contain the virus.


2020-11-06_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Nov 2020

2020-11-06_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …


Attentional Measures Of Memory In Typically Developing And Hypoxic–Ischemic Injured Infants, Jennifer B. Wagner, Adeline Jabès, Agatha Norwood, Charles A. Nelson Nov 2020

Attentional Measures Of Memory In Typically Developing And Hypoxic–Ischemic Injured Infants, Jennifer B. Wagner, Adeline Jabès, Agatha Norwood, Charles A. Nelson

Publications and Research

Hypoxic–ischemic injury (HII) at birth has been found to relate to differences in development, including decreased memory performance. The current study assessed recognition memory in 6- and 12-month-old HII infants and typically developing (TD) infants using two eye-tracking paradigms well suited to explore explicit memory processes early in life: visual paired comparison (VPC) and relational memory (RM). During the VPC, infants were familiarized to a face and then tested for their novelty preference immediately and after a two-minute delay. At 6 months, neither HII nor TD showed a VPC novelty preference at immediate delay, but at 12 months, both groups …


2020-11-06_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Nov 2020

2020-11-06_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


Is G-Csf Dangerous In Covid-19: Why Not Use Gm-Csf?, Hillard M. Lazarus Nov 2020

Is G-Csf Dangerous In Covid-19: Why Not Use Gm-Csf?, Hillard M. Lazarus

Faculty Scholarship

No abstract provided.


Mutations In Grk2 Cause Jeune Syndrome By Impairing Hedgehog And Canonical Wnt Signaling., Michaela Bosakova, Sara P. Abraham, Alexandru Nita, Eva Hruba, Marcela Buchtova, S Paige Taylor, Ivan Duran, Jorge Martin, Katerina Svozilova, Tomas Barta, Miroslav Varecha, Lukas Balek, Jiri Kohoutek, Tomasz Radaszkiewicz, Ganesh V. Pusapati, Vitezslav Bryja, Eric T. Rush, Isabelle Thiffault, Deborah A. Nickerson, Michael J. Bamshad, University Of Washington Center For Mendelian Genomics, Rajat Rohatgi, Daniel H. Cohn, Deborah Krakow, Pavel Krejci Nov 2020

Mutations In Grk2 Cause Jeune Syndrome By Impairing Hedgehog And Canonical Wnt Signaling., Michaela Bosakova, Sara P. Abraham, Alexandru Nita, Eva Hruba, Marcela Buchtova, S Paige Taylor, Ivan Duran, Jorge Martin, Katerina Svozilova, Tomas Barta, Miroslav Varecha, Lukas Balek, Jiri Kohoutek, Tomasz Radaszkiewicz, Ganesh V. Pusapati, Vitezslav Bryja, Eric T. Rush, Isabelle Thiffault, Deborah A. Nickerson, Michael J. Bamshad, University Of Washington Center For Mendelian Genomics, Rajat Rohatgi, Daniel H. Cohn, Deborah Krakow, Pavel Krejci

Manuscripts, Articles, Book Chapters and Other Papers

Mutations in genes affecting primary cilia cause ciliopathies, a diverse group of disorders often affecting skeletal development. This includes Jeune syndrome or asphyxiating thoracic dystrophy (ATD), an autosomal recessive skeletal disorder. Unraveling the responsible molecular pathology helps illuminate mechanisms responsible for functional primary cilia. We identified two families with ATD caused by loss-of-function mutations in the gene encoding adrenergic receptor kinase 1 (ADRBK1 or GRK2). GRK2 cells from an affected individual homozygous for the p.R158* mutation resulted in loss of GRK2, and disrupted chondrocyte growth and differentiation in the cartilage growth plate. GRK2 null cells displayed normal cilia morphology, yet …


Identification Of Non-Cholinergic Receptors In Embryonic Zebrafish Skeletal Muscle, Rhiannon Huffines Nov 2020

Identification Of Non-Cholinergic Receptors In Embryonic Zebrafish Skeletal Muscle, Rhiannon Huffines

Scholars Week

No abstract provided.


Medical School Watercooler Newsletter - November 5, 2020, Lindsey Lyle Nov 2020

Medical School Watercooler Newsletter - November 5, 2020, Lindsey Lyle

Watercooler Newsletter

This is the November 5, 2020 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

  • Slauterbeck named chair of orthopaedic surgery at USA College of Medicine
  • Mark your calendar for upcoming grand rounds
  • Gassman receives funding to explore reducing chemotherapy side effects
  • Applications open for SouthMed Prep Scholars Program
  • Med School Café video available: 'COVID-19 and Diabetes'


2020-11-05_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services Nov 2020

2020-11-05_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …


2020-11-05_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Nov 2020

2020-11-05_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


Coronavirus Update 11-5-2020, The Coronavirus Planning Team Nov 2020

Coronavirus Update 11-5-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

Since we communicated with you on Tuesday, we have had a total of 35 new COVID-19 cases—29 of which are on campus. This is, unfortunately, in line with spikes in cases both regionally and nationally and at other area universities. Part of the reason is that people everywhere are letting their guard down.


Canagliflozin Extends Life Span In Genetically Heterogeneous Male But Not Female Mice., Richard A Miller, David E Harrison, David B Allison, Molly A. Bogue, Lucas Debarba, Vivian Diaz, Elizabeth Fernandez, Andrzej Galecki, W Timothy Garvey, Hashan Jayarathne, Navasuja Kumar, Martin A Javors, Warren C Ladiges, Francesca Macchiarini, James Nelson, Peter C. Reifsnyder, Nadia Rosenthal, Marianna Sadagurski, Adam B Salmon, Daniel L Smith, Jessica M Snyder, David B Lombard, Randy Strong Nov 2020

Canagliflozin Extends Life Span In Genetically Heterogeneous Male But Not Female Mice., Richard A Miller, David E Harrison, David B Allison, Molly A. Bogue, Lucas Debarba, Vivian Diaz, Elizabeth Fernandez, Andrzej Galecki, W Timothy Garvey, Hashan Jayarathne, Navasuja Kumar, Martin A Javors, Warren C Ladiges, Francesca Macchiarini, James Nelson, Peter C. Reifsnyder, Nadia Rosenthal, Marianna Sadagurski, Adam B Salmon, Daniel L Smith, Jessica M Snyder, David B Lombard, Randy Strong

Faculty Research 2020

Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of glucose. In the context of the mouse Interventions Testing Program, genetically heterogeneous mice were given chow containing Cana at 180 ppm at 7 months of age until their death. Cana extended median survival of male mice by 14%. Cana also increased by 9% the age for 90th percentile survival, with parallel effects seen at each of 3 test sites. Neither the distribution of inferred cause of death nor incidental pathology …


Using Participatory Mapping To Diagnose Upstream Determinants Of Health And Prescribe Downstream Policy-Based Interventions, Jason A. Douglas, Andrew M. Subica, Laresha Franks, Gilbert Johnson, Carlos Leon, Sandra Villanueva, Cheryl T. Grills Nov 2020

Using Participatory Mapping To Diagnose Upstream Determinants Of Health And Prescribe Downstream Policy-Based Interventions, Jason A. Douglas, Andrew M. Subica, Laresha Franks, Gilbert Johnson, Carlos Leon, Sandra Villanueva, Cheryl T. Grills

Health Sciences and Kinesiology Faculty Articles

Participatory mapping is a powerful methodology for working with community residents to examine social and environmental determinants of public health disparities. However, this empowering methodology has only been applied sparingly in public health research and practice, with limited examples in the literature. To address this literature gap, we 1) review participatory mapping approaches that may be applied to exploring place-based factors that affect community health, and 2) present a mixed-methods participatory geographic information systems (PGIS) examination of neighborhood assets (eg, streetlights) and challenges (eg, spaces of crime and violence) related to access to public parks in South Los Angeles, California. …