Medicine and Health Sciences Commons^™

Pharmacokinetics And Antibacterial Activity Of Fosfomycin Against Escherichia Coli From Urinary Tract Infected Dogs, Nattha Jariyapamornkoon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Using old or uncommon drugs as alternative choices are interesting option to avoid drug resistance problems. Fosfomycin is an old antibacterial drug with broad spectrum and excreted via urine in active form. Fosfomycin tromethamine (FOS) has been approved to treat uncomplicated urinary tract infection (UTI) in women by FDA. However, in dogs, FOS data is inadequate and precise dosages have not been established yet. Thus, this study aims to determine pharmacokinetics (PK) and pharmacodynamics (PD) of FOS in E. coli from dog with UTI. A total of 6 healthy male beagle dogs were administered with FOS in 3 different dosages …

Unf Covid-19 Testing: Informed Consent, University Of North Florida

UNF COVID-19 Response

Consent form for COVID-19 testing

Covid-19 Self-Screening Guidance, Unf Human Resources

UNF COVID-19 Response

No abstract provided.

Unf Covid-19 Education Program, Center For Professional Development And Training

UNF COVID-19 Response

No abstract provided.

Emergency Relief For Unf Students, University Of North Florida

UNF COVID-19 Response

As part of University of North Florida's response to the COVID-19 Pandemic, it crowdfunded emergency relief for UNF students.

Unf Tennis Complex Covid-19 Protocol, University Of North Florida Athletics

UNF COVID-19 Response

UNF Tennis Complex Covid-19 protocols

Unf Preschool Covid-19 Pandemic: Policy For Lab Tested Positive Case, Unf Preschool

UNF COVID-19 Response

Preschool Policy on Covid-19 positive cases

Cares Act Student Emergency Aid Funding Faqs, Unf One-Stop Student Services

UNF COVID-19 Response

Frequently Asked Questions on the Cares Act and Student funding

Covid-19 Information Libguide, Thomas Carpenter Library

UNF COVID-19 Response

Modified Library protocols, policies, and procedures 2020

Self-Quarantine/Isolation Procedures, Unf Human Resources

UNF COVID-19 Response

Covid Quarantine and isolation protocols

A Rare Case Of Herpes Zoster Ophthalmicus After Photodynamic Therapy, Madison Bradley, Sonal Muzumdar, Neda Shahriari, Marti J. Rothe, Madina Falcone

Biology Undergraduate Publications

Dear Editors:

Topical photodynamic therapy (PDT) is frequently used in dermatology to treat actinic keratoses (AKs) and superficial nonmelanoma skin cancers (Ibbotson et al., 2019). Herein, we present an extremely rare case of herpes zoster ophthalmicus (HZO) after PDT.

The Internationlization Of Sport Industry: A Study Of Thailand Sport Equipment Firms, Apithai Bumrungpanictarworn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Entering international markets is one of many key strategies to ensure high and sustainable growth of the firm. It refers to how firms want to do business activities and their engagement in foreign markets. Many studies on the international market have been focused on entry mode strategies which is one of the most critical decisions in a firm's internationalization strategy. This research aimed to examine which factors influenced the entry mode decisions to enter foreign markets for sports equipment firms. A qualitative approach and multiple case study technique were used in this research. Important theories related to entry mode, such …

Effects Of Social Interaction And Transformational Leadership On Sport Event Volunteers' Perception Of Team Member Exchange, Kasidech Treethong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study contributes to the management of sport event volunteers, where particular team member exchange is crucial in promoting teamwork among sport event volunteers. The objectives of this study are 1) to examine the effects of social interaction and transformational leadership on the sport event volunteers' perception of team member exchange and 2) to examine the interaction effect between social interaction and transformational leadership on the sport event volunteers' perception of team member exchange. This study employed a field experiment and a post-experiment interview at the 2019 FIVB Volleyball Nations League Thailand. Subjects (n = 64) were assigned by stratified …

Recovery Of Isolated Pancreatic Isletsderived From Gut Leak-Induced Diabetes Type Ii Mouse Model, Adretta Soedarmanto

Chulalongkorn University Theses and Dissertations (Chula ETD)

Gut leak in the obese patient was known to be one of the predisposing factors causing diabetes type II. Indeed, the interleukin-10 (IL-10) plays a key role in gut mucosa homeostasis preventing the gut leak. Nevertheless, the linkage of diabetes type 2 caused by gut leak with IL-10 deficiency in the non-diabetes patient has not been investigated yet. Islets transplantation is known as the best alternative treatment for diabetes. The culture of isolated islets is still facing difficulties to preserve the morphology, viability, and functionality. Therefore, the present study was aiming to prove the concept of gut-leak on IL-10 deficient …

The Influence Of Sports Facilities' Accessibility, Motivation, And Satisfaction On Word-Of-Mouth And Re-Participation Intentions Of Athletes With Physical Disabilities, Thee Trongjitpituk

Chulalongkorn University Theses and Dissertations (Chula ETD)

More than a billion people are estimated to live with some form of disability, or about 15% of the world's population and the number is still growing. People with disabilities are less likely to participate in sports due to several physical barriers they face. In an effort to find ways to increase the sports participation rate of people with disabilities, the concept of marketing (satisfaction, word-of-mouth intention, and re-participation intention) was applied to the field of accessibility for the first time. This study consisted of three objectives: (1) to find out the dimension of sports facilities' accessibility and motivation, (2) …

Effect Of Dietary Microencapsulated Organic Acid And Essential Oil On Sow Performance And Nursery Piglet Growth Performance And Fecal Bacteria, Aprilia Rizky Riadini

Chulalongkorn University Theses and Dissertations (Chula ETD)

The effect of feed supplementation with microencapsulated organic acids and essential oils (MOE, Porcinate+) in feed was investigated according to sow and nursery pig growth performances, and fecal bacteria population. Experiment 1: healthy three hundred and twenty sows during its late gestation period (7 days before farrowing) until the weaning phase (28 days after farrowing) were randomly divided as control group (160 sows) which was fed with basal diet, and treatment group (160 sows), which was fed with basal diets supplemented with 2 kilograms (kg) of MOE in 1 ton of feed. Each of 4 replications was composed of 40 …

Porcine Reproductive And Respiratory Syndrome Virus: Genetic Diversity, Pathogenesis And Modified-Live Vaccines, Adthakorn Madapong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Porcine reproductive and respiratory syndrome virus (PRRSV) is a causative agent of PRRS that reproductive failure in sows and respiratory problems in piglets is the hallmark of the disease. Recently, several PRRSV modified live vaccines (MLV) are available, and vaccine selection is a concern. Therefore, the objectives of this study were: 1) to investigate the genetic diversity of Thai PRRSV isolates during 2001-2017; 2) to evaluate the pathogenicity of Thai PRRSV isolates; 3) to determine the efficacy of PRRSV MLV against Thai field PRRSV infection and 4) to investigate the effectiveness of PRRSV MLV when administered via intramuscular (IM) and …

Genetic Characteristics Of Antimicrobial Resistance In Escherichia Coli Isolated From Pigs, Pork And Humans In Thailand And Lao Pdr Border Provinces, Chanika Pungpian

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this study were to monitor the prevalence of antimicrobial resistance (AMR) among Escherichia coli isolated from pigs, pork and humans in Thailand-Laos border areas, characterize AMR of E. coli isolated from pigs, pork and humans in Thailand-Laos border areas, and compare the resistance to last-line antimicrobials of E. coli and Salmonella isolated from pigs and pork in Thailand-Laos and Thai-Cambodia border areas. Three study projects were conducted. Project 1 demonstrated the results of phenotypic and genotypic monitoring of AMR in E. coli in pigs, pork, and humans in Thailand and Lao PDR border provinces. A total of …

Microbiological Quality Of And Antimicrobial Resistance In Commercial Probiotic Products For Food Animals In Thailand, Hoang My Tran

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 45 commercial probiotic products for food animals were investigated for the number of viable cells, bacterial species and the presence of antimicrobial resistance (AMR) genes. All products were enumerated for viable bacterial cells of Lactobacillus, Bacillus and Enterococcus. Confirmation of species was carried out by multiplex Polymerase Chain Reaction (PCR) for Lactobacillus (n=20), Enterococcus (n=20), and Amplified Ribosomal DNA Restriction Analysis (ARDRA) for Bacillus (n=190). The presence of Clostridium species was examined by PCR. The contamination of E. coli and Salmonella was also determined. Minimal Inhibitory Concentrations (MICs) for 14 antimicrobials was examined in the bacterial isolates …

Localization Of Tilapia Tilapinevirus By In Situ Hybridization In The Brain Of Nile Tilapia (Oreochromis Niloticus), Hung Dinh Nguyen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tilapia tilapinevirus or tilapia lake virus (TiLV) is an emerging virus that poses a significant negative impact on farmed tilapia globally. Abnormal behaviours such as lethargy, loss of appetite, erratic swimming, stop schooling have been recorded during disease occurrence, which is possibly linked to brain activities. Previous studies described detection of the virus in multiple organs of infected fish; however, little is known about the in-depth localization of the virus in the central nervous system. Herein, we determined the distribution of TiLV and histopathological alterations in the entire brain of Nile tilapia experimentally infected fish. By in situ hybridization (ISH) …

Detection Of Indicator And Pathogenic Bacteria In Raw Vegetables And Fruits Sold In Fresh Markets And Supermarkets, Bangkok, Thailand, Jutanat Srisamran

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to compare the concentrations of fecal coliforms and Escherichia coli, and the contamination of Salmonella, Shigella, E. coli O157: H7 and Listeria monocytogenes in raw vegetables and fruits between fresh markets and supermarkets in Bangkok, Thailand. A total of 405 produce samples, consisting of sweet basil, spring onion, coriander, cabbage, lettuce, cucumber and tomato, were randomly collected from seven fresh markets (n=203) and 29 supermarkets (n=202) in seven districts of Bangkok between June 2018 and July 2019. T-test and one-way ANOVA were used to compare the concentrations of fecal coliforms and E. coli (log10MPN/g) between fresh markets …

A Study Of Using Corncob, Aspen Shaving, Dried Water Hyacinth And Banana Midrib As Bedding For Laboratory Mice, Nantaporn Maytayapirom

Chulalongkorn University Theses and Dissertations (Chula ETD)

A study of using corncob, aspen shaving, dried water hyacinth and banana midrib as bedding for laboratory mice. The objective of this study was to evaluate the physical characteristics (i.e., absorbency and surface moisture), the physiological effects and intracage ammonia level of 4 types of beddings in laboratory mice. This study was divided into two parts. In the first part, the fluid absorption properties of these four beddings were studied using measurement of liquid absorption and the surface moisture. The results showed that the volumetric absorbency of aspen shaving was significantly higher than other beddings. While, the surface moisture showed …

The Study Of Changes In Gene Regulation Of Serotonin Signaling Pathway And Circulating Serotonin Concentration In Dogs With Pulmonary Hypertension Due To Degenerative Mitral Valve Disease, Nattawan Tangmahakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Pulmonary hypertension (PH) is an abnormal increase in pulmonary vascular pressure. In dogs, PH is commonly found secondary to degenerative mitral valve disease (DMVD), especially in small breed dogs. Serotonin, a biogenic amine playing an essential role in both physiology and abnormalities of several organs, is a vasoactive substance that has been one of the suspicious mediators for the development of PH. Both local and circulating effects of serotonin have been investigated to discover the involvement of serotonin and the pathogenesis of PH in both humans and animals. The present study aimed to investigate the local serotonin signaling in lung …

Targeted Surveillance Of Potential Zoonotic Respiratory And Enteric Viruses In Dogs In Bangkok, Thailand, Kamonpan Charoenkul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Human-dog interface poses a risk of transmission and spread of zoonotic viruses. The objective of the thesis entitled is to survey and genetic characterize zoonotic viruses in dogs and humans who have high-risk occupations and in close contact with dogs. This thesis contains 8 topics. The results of the first to third topics were the surveillance of respiratory viruses in dogs including Canine Parainfluenza type 5 (CPIV-5), Canine influenza virus (CIV) and Coronavirus (CoV). The nasal swab samples were collected from dogs with respiratory signs during 2015-2018. The results showed that the occurrence of CPIV-5, CIV and CoV were 5.6% …

Comparison Of Laser Class 1m And Class 4 Applications In Canine Cranial Cruciate Ligament Rupture Evaluated By Clinical Outcomes And Ultrasonography, Noppakrit Ekakaraworapong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Nineteen dogs diagnosed of cranial cruciate ligament rupture were included in this study before TPLO was performed. They were classified into 3 groups which consisted of control, low-level laser therapy class 1M and low-level laser therapy class 4 groups. The number of each group were 4, 8 and 7 dogs, respectively, and the duration of treatment protocol was 4 weeks consecutively. On the first day of the study, dogs were examined and assessed of the clinical signs such as lameness score, synovial fluid analysis, canine brief pain inventory questionnaire (CBPI) and ultrasonographic score. In ultrasonographic monitoring, ultrasonographic scores on synovial …

Efficiency And Clinical Outcomes Of Platlet-Rich Plasma Therapy On Caninecoxofemoral Osteoarthritis, Patama Arunrattanakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to find out for the optimal technique to prepare plasma with highest platelet concentration in platelet rich plasma (PRP), as well as determine the result of autologous PRP from the dogs with osteoarthritis(OA) condition. It was shown that the PRP could reduce inflammation, cell regeneration, and enhance angiogenesis to support the injured tissue. This study was composed of two phases; the first phase was aimed to find the best centrifugation speed and time that could be able to produce the plasma with the highest platelet concentration by conducting the experiment from a total of …

Surveillance Of Coronaviruses In Fruit Bats (Pteropus Lylei) Of Thailand, Pichamon Moolthep

Chulalongkorn University Theses and Dissertations (Chula ETD)

Coronavirus (CoV) is an enveloped single positive-stranded RNA virus CoV can cause enteric and respiratory diseases in mammals, avian and human. Bats are the natural reservoir of CoVs and distribute all over Thailand. Sample collection was performed in two bat colonies in Ayutthaya and Saraburi provinces during March 2018 - February 2019. Total 1,487 samples were collected from 730 bats. The bat species identification via morphological measurement and cytochrome B detection showed that bats in both colonies are Lyle's flying fox (Pteropus lylei). The results of CoV detection showed that 4.30% of samples were positive to CoV. Phylogenetic analysis showed …

Effects Of Algae-Derived Ss-Glucan Supplementation On Production Performances And Specific Immune Responses In Nursery To Growing Pigs, Sh.Boonnithi Chuaychu

Chulalongkorn University Theses and Dissertations (Chula ETD)

เบต้ากลูแคนเป็นสารเสริมในอาหารสัตว์ที่มีการใช้กันอย่างแพร่หลายในอุตสาหกรรมการเลี้ยงสุกร ถึงแม้ว่าการเสริมสารเบต้ากลูแคนในสูตรอาหารสุกร จะเชื่อว่าสามารถช่วยพัฒนาการเจริญเติบโตและปรับการทำงานของภูมิคุ้มกันในสุกรได้ แต่อย่างไรก็ตาม ในปัจจุบันยังไม่มีข้อมูลการศึกษาที่ชัดเจนเกี่ยวกับผลของการเสริมเบต้ากลูแคนที่สกัดมาจากสาหร่ายต่ออัตราการเจริญเติบโตและการตอบสนองทางภูมิคุ้มกันโดยเฉพาะระบบภูมิคุ้มกันแบบจำเพาะในสุกร ดังนั้นการศึกษานี้จึงมีวัตถุประสงค์เพื่อประเมินผลของการใช้สารเสริมเบต้ากลูแคนจากสาหร่ายในอาหารสุกรต่อประสิทธิภาพการเจริญเติบโตและการตอบสนองทางภูมิคุ้มกันแบบจำเพาะในสุกรอนุบาลและสุกรขุนเล็ก โดยแบ่งสุกรหย่านมสามสายพันธุ์เป็น 3 กลุ่มการทดลอง ได้แก่ กลุ่มควบคุมที่ได้รับอาหารสูตรมาตรฐาน กลุ่มทดลองที่ 2 และ 3 ได้รับอาหารชนิดเดียวกันที่เสริมด้วยสารเสริมเบต้ากลูแคนจากสาหร่ายในปริมาณ 100 และ 200 กรัมต่อตันตามลำดับ จากการทดลอง ไม่พบความแตกต่างอย่างมีนัยสำคัญของประสิทธิภาพการผลิตและอัตราการเจริญเติบโตของสุกรสุกร การทดสอบการตอบสนองของระบบภูมิคุ้มกันที่จำเพาะหลังการฉีดวัคซีน CSFV และ PRRSV พบว่าสุกรที่ได้รับสารเสริมเบต้ากลูแคนจากสาหร่ายในอาหาร มีระดับ neutralizing antibody ต่อ CSFV สูงขึ้นอย่างมีนัยยะสำคัญ นอกจากนี้ พบการเพิ่มขึ้นของจำนวนเซลล์ CD4+(T lymphocytes) และ CD4+CD8+ (putative memory T lymphocytes) ซึ่งสร้างไซโตคายน์ IFN-g+ ที่มีความจำเพาะต่อ CSFV และ PRRSV ในกลุ่มสุกรที่ได้รับสารเสริมเบต้ากลูแคนจากสาหร่ายอีกด้วย จากการศึกษาสรุปได้ว่า ถึงแม้ว่าการให้สารเสริมเบต้ากลูแคนจะไม่สามารถเสริมสมรรถภาพการผลิตของสุกรได้ แต่มีคุณสมบัติทางชีวภาพในการเป็นสารกระตุ้นภูมิคุ้มกันซึ่งอาจเป็นการเพิ่มความต้านทานโรคติดเชื้อไวรัสในสุกรอนุบาลและสุกรขุนเล็กได้

Development Of Conventional And Taqman Real-Time Polymerase Chain Reaction Methods For Detection Of Liver Fluke Infection With Platynosomum Spp. In Cat Feces, Shane Thiha Soe

Chulalongkorn University Theses and Dissertations (Chula ETD)

The Platynosomum spp. fluke is the etiologic agent of platynosomiasis responsible for hepatobiliary diseases in cats. Coprological examination using centrifugal sedimentation technique is the gold standard method for detection of Platynosomum spp.'s eggs. However, microscopic examination method has a limited sensitivity, particularly in cases of complete biliary obstruction and inconsistent egg shedding. To circumvent these problems, this study aims to develop molecular-based methods for detecting Platynosomum spp. infection in cat feces including conventional PCR (cPCR) and TaqMan real-time PCR methods targeting ITS1 region. From a total number of 120 cat fecal samples, when compared to microscopic examination, the cPCR method …

Surveillance And Histopathological Study Of Microplastics In Marine Fish From The Gulf Of Thailand, Sirawich Srisiri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Microplastic (MP) problems have been threatened aquatic environment worldwide for decades. This study demonstrated current MP contamination characteristics in marine food fishes from the upper Gulf of Thailand. MPs were found in gastrointestinal tracts of 46.86% of fish samples, which were 1.556±0.47 pieces per fish or 0.035±0.014 pieces per gram of fish bodyweight. No plastics were detected from muscle, liver, kidney or gonad of the fishes. There was a significant relationship between MP contamination and fish species or the fish grouping. Benthic fish had a higher contamination rate than pelagic fish. Fiber-type and blue color were the most abundant MPs …