Medicine and Health Sciences Commons^™

A Hybrid System Dynamics, Discrete Event Simulation And Data Envelopment Analysis To Investigate Boarding Patients In Acute Hospitals, Leila Keshtkar, Wael Rashwan, Waleed Abo Hamad, Amr Arisha

Articles

Timely access to health services has become increasingly difficult due to demographic change and aging people growth. These create new heterogeneous challenges for society and healthcare systems. Congestion at acute hospitals has reached unprecedented levels due to the unavailability of acute beds. As a consequence, patients in need of treatment endure prolonged waiting times as a decision whether to admit, transfer, or send them home is made. These long waiting times often result in boarding patients in different places in the hospital. This threatens patient safety and diminishes the service quality while increasing treatment costs. It is argued in the …

A Pilot Study For Early Detection Of Oral Premalignant Diseases Using Oral Cytology And Raman Micro-Spectroscopy: Assessment Of Confounding Factors, Isha Behl, Genecy Calado, Alison Malkin, Stephen Flint, Sheila Galvin, Claire Healy, Marina Leite Pimentel, Hugh Byrne, Fiona Lyng

Articles

This study demonstrates the efficacy of Raman micro-spectroscopy of oral cytological samples for differentiating dysplastic, potentially malignant lesions from those of normal, healthy donors. Cells were collected using brush biopsy from healthy donors (n = 20) and patients attending a Dysplasia Clinic (n = 20). Donors were sampled at four different sites (buccal mucosa, tongue, alveolus, gingiva), to ensure matched normal sites for all lesions, while patient samples were taken from clinically evident, histologically verified dysplastic lesions. Spectra were acquired from the nucleus and cytoplasm of individual cells of all samples and subjected to partial least squares-discriminant analysis. Discriminative sensitivities …

Effect Of Hemolysis On Fourier Transform Infrared And Raman Spectra Of Blood Plasma, Dinesh Medipally, Daniel Cullen, Valérie Untereiner, Jane Bryant, Ganesh D. Sockalingum, Thi Nguyet Que Nguyen, Emma Noone, Shirley Bradshaw, Marie Finn, Mary Dunne, Aoife M. Shannon, John Armstrong, Aidan Meade, Fiona Lyng

Articles

Hemolysis is a very common phenomenon and is referred as the release of intracellular components from red blood cells to the extracellular fluid. Hemolyzed samples are often rejected in clinics due to the interference of hemoglobin and intracellular components in laboratory measurements. Plasma and serum based vibrational spectroscopy studies are extensively applied to generate spectral biomarkers for various diseases. However, no studies have reported the effect of hemolysis in blood based vibrational spectroscopy studies. This study was undertaken to evaluate the effect of hemolysis on infrared and Raman spectra of blood plasma. In this study, prostate cancer plasma samples (n …

Comparability Of Raman Spectroscopic Configurations: A Largescale Cross-Laboratory Study, Shuxia Guo, Hugh Byrne, Shiyamala Duraipandian, Fiona Lyng, Claudia Beleites, Ute Neugebauer

Articles

The variable configuration of Raman spectroscopic platforms is one ofthe major obstacles in establishing Raman spectroscopy as a valuable physicochemicalmethod within real-world scenarios such as clinical diagnostics. For such real worldapplications like diagnostic classification, the models should ideally be usable to predictdata from different setups. Whether it is done by training a rugged model with data frommany setups or by a primary-replica strategy where models are developed on a‘primary’setup and the test data are generated on‘replicate’setups, this is only possible if the Raman spectra from different setups are consistent, reproducible, and comparable.However, Raman spectra can be highly sensitive to the …

Raman Microspectroscopic Study For The Detection Of Oral Field Cancerisation Using Brush Biopsy Samples, Isha Behl, Genecy Calado, Anika Vishwakarma, Stephen Flint, Sheila Galvin, Claire Healy, Marina Leite Pimentel, Alison Malkin, Hugh Byrne, Fiona Lyng

Articles

Field cancerisation (FC) is potentially an underlying cause of poor treatment outcomes of oral squamous cell carcinoma (OSCC). To explore the phenomenon using Raman microspectroscopy, brush biopsies from the buccal mucosa, tongue, gingiva and alveolus of healthy donors (n = 40) and from potentially malignant lesions (PML) of Dysplasia Clinic patients (n = 40) were examined. Contralateral normal samples (n = 38) were also collected from the patients. Raman spectra were acquired from the nucleus and cytoplasm of each cell, and subjected to partial least squares-discriminant analysis (PLS-DA). High discriminatory accuracy for donor and PML samples was achieved for both …

Dustbowl Waters: Doctrinal And Legislative Solutions To Save The Ogallala Aquifer Before Both Time And Water Run Out, Warigia M. Bowman

Articles, Chapters in Books and Other Contributions to Scholarly Works

Eighty-three years after the Dust Bowl, residents of America’s High Plains face a dire threat: their primary aquifer faces depletion, and entire sections of the country are set to run out of groundwater by the end of the century or sooner. The Ogallala Aquifer provides a significant amount of America’s agricultural irrigation water and is a primary source of drinking water for Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming. This Article argues that policymakers should slow the Aquifer’s depletion rate by implementing changes to irrigation technology, crop choice, consumer behavior, legal doctrine, and legislation. This Article …

2020 Nursing Accreditation Report, Georgia Southern University Libraries

Program Accreditation Reports (2013-2023)

For additional information on G eorgia Southern Libraries r esources, p lease s ee t he included d ocument, L ibrary R esources f or Nursing, f or a dditional, i n-depth i nformation on h oldings and r esources h oused b y the G eorgia S outhern L ibraries t o s upport t he research a nd a cademic needs of t he S chool o f N ursing.

Corpus Cavernosum Abscess Secondary To Traumatic Perforation Of Urethral Diverticulum, Thomas C. Gore, Anna Schepcoff, Domenick Sorresso

West Florida Division GME Research Day 2020

A corpus cavernosum abscess is a rare condition. Usual etiologies include penile injection of erectile dysfunction medications or illicit drugs, priapism, sexually transmitted infections, and trauma; however, there have been reported cases of idiopathic etiology. The most common causative organisms include Staphylococcus aureus, Streptococci, and Bacteroides [1]. Diagnosis is typically made clinically and through imaging (computed tomography [CT] and ultrasound). The first-line treatment is the use of intravenous (IV) antibiotics and surgical drainage. More conservative treatment, however, includes aspiration in conjunction with IV antibiotics [2-3]. Urethral diverticulum (UD) is the formation of a saccular outpouching of the urethral lumen. Symptoms …

A Rare Case Of Trichilemmal Carcinoma: Histology And Management, Lisa F. Fronek, Allyson Brahs, Maheera Farsi, Richard Miller

West Florida Division GME Research Day 2020

Trichilemmal carcinoma (TC) is a rare, malignant, adnexal neoplasm that is derived from the outer root sheath (ORS) of the hair follicle. These tumors predominantly occur in elderly patients on sun-exposed areas, specifically on the head and neck with the face defined as the most common location. The mean age of diagnosis is 70 years old with a slight male predominance. These lesions are commonly identified as a papular, nodular, and sometimes, exophytic. They generally arise de-novo, but may also derivate from an underlying proliferating trichilemmal cyst with a loss of p53, a seborrheic keratosis, a nevus sebaceous, or a …

Localized Cytokine Responses To Total Knee Arthroplasty And Total Knee Revision Complications, Nicole Prince, Julia A. Penatzer, Matthew J. Dietz, Jonathan W. Boyd

Faculty & Staff Scholarship

Background

The study of localized immune-related factors has proven beneficial for a variety of conditions, and one area of interest in the field of orthopaedics is the impact of implants and localized infections on immune response. Several cytokines have shown increased systemic concentrations (in serum/plasma) in response to implants and infection, but tissue-level cytokines have not been investigated as thoroughly.

Methods

This exploratory study investigated tissue-level cytokines in a cohort of patients (N = 17) in response to total knee arthroplasty and total knee revision to better understand the immune response to implants and localized infection (e.g., prosthetic joint infection). …

Technology-Based End-Of-Life Planning For An Underserved Population, Haley Kirkpatrick

Doctor of Nursing Practice (DNP) Projects

Problem: Research indicates a low-income status and ethnic and racial diversity is a barrier to ACP engagement.

Context: This project took place at a Federally Qualified Heath Center located in Northern California which serves approximately 200,000 diverse and economically disadvantaged patients.

Methods: The primary intervention was dissemination of an email to patients 50 and older, via their health system email account. The email included a direct link to PREPARE, an online advance care planning technology tool. A secondary intervention was a presentation to primary care providers that focused on end-of-life-care planning tools and communication strategies.

Results: The email was distributed …

Spatially Fractionated Radiation Therapy: History, Present And The Future, Weisi Yan, Mohammad K. Khan, Xiaodong Wu, Charles B. Simone Ii, Jiajin Fan, Eric Gressen, Xin Zhang, Charles L. Limoli, Houda Bahig, Slavisa Tubin, Waleed F. Mourad

Department of Radiation Oncology Faculty Papers

No abstract provided.

Stress And Job Satisfaction As Predictors Of Teacher Turnover Intentions, Alrick Thompson

Walden Dissertations and Doctoral Studies

High teacher turnover is problematic because of the costs associated with recruiting and training new hires. However, some of the factors originating outside of the working environment that may influence teacher turnover intentions are not fully understood. The purpose of this quantitative correlational design study was to examine the extent to which job satisfaction, commuting stress, and financial stress are predictors of teacher turnover intentions. The study involved a purposive sampling of 227 teachers within a school district in the South Eastern part of the United States. Hobfoll’s conservation of resources theory provided the theoretical framework for the study. Validated …

Impact Of Nursing Education On Dysphagia Screening Knowledge, Jeanette Doreen Brumm

Walden Dissertations and Doctoral Studies

Dysphagia is a common, life-threatening complication potentially experienced by patients with acute stroke. Complications related to dysphagia can lead to aspiration pneumonia, morbidity, and mortality. Thus, early identification of dysphagia is necessary for improving patient outcomes and avoiding adverse health consequences. Nurses have the unique opportunity to impact patient care by increasing knowledge of evidenced-based treatment of dysphagia in acute ischemic stroke patients. Therefore, the project question asked whether Registered Nurse (RN) dysphagia education could improve nursing knowledge of dysphagia screening. The purpose of this project was to increase RN knowledge regarding dysphagia screening using the Yale Swallow Protocol (YSP). …

Improving Nursing Knowledge Of Heart Failure Discharge Self-Care Instructions, Maria Patricia Picar Deza

Walden Dissertations and Doctoral Studies

Patients with heart failure (HF) have recurrent symptoms that lead to frequent hospital readmissions. Moreover, HF is one of the leading causes of 30-day hospital readmissions. Evidence shows that patients with a high level of HF self-care have decreased readmissions. HF self-care education is commonly delivered by the nurse at hospital discharge, and the patient’s transition to self-care is a critical point in the continuum of care. However, nurses must be knowledgeable of patient self-care in HF to effectively convey this information to the patient upon discharge. Therefore, this staff education project question asked whether nursing knowledge of HF patient …

Tetanus Immunity Among Adults In The Democratic Republic Of The Congo, Sue K. Gerber

Walden Dissertations and Doctoral Studies

Although tetanus is not a contagious disease, it can be deadly for people who are exposed and do

not have protective immunity against tetanus, which can be acquired only through vaccination.

Most studies on adult tetanus protective immunity are from high-income countries; limited

studies occur in Africa, and none has been reported from the Democratic Republic of the Congo

(DRC). This study sought to determine protective immunity against tetanus among adults in

DRC in relation to their age, sex, place of residence, and for women, antenatal care. The primary

purpose of this observational cross-sectional study using a nested serosurvey within …

Development Of A Clinical-Academic-Community Collaboration To Improve Health Literacy, Daniela B. Friedman Ph.D., Michelle A. Arent, Brooks Yelton Ma, Lmsw, Mayank Sakhuja, Venice E. Haynes, Samuel Noblet, Heather M. Brandt Ph.D., Ches, William D. Isenhower, Abraham Wandersman, Diana Zona, Cyndi New, Delores Fedrick, Jonathan Scaccia, Larisa Bruner

Faculty Publications

Limited health literacy is associated with poor patient health outcomes and increased hospitalization rates. Patient-provider communication plays an important role in patient health literacy and the understanding of medical terminology. This study demonstrates how a collaboration between clinical, academic, and community partners was instrumental in the design and implementation of a clinic readiness assessment and a clinic-based pilot intervention to encourage patient-provider communication and improve patient health literacy. A state hospital association, academic research team, and community adult literacy center director collaborated to develop a 60-item clinic readiness assessment and an evidence-informed pilot intervention. The clinic readiness assessment captured clinics’ …

Bnasnpdb: An Interactive Web Portal For The Efficient Retrieval And Analysis Of Snps Among 1,007 Rapeseed Accessions, Tao Yan, Qian Wang, Antony Maodzeka, Dezhi Wu, Lixi Jiang

Publications

The rapid development of high-throughput sequencing technology and the decrease in sequencing costs provide valuable resources and great opportunities for researchers to investigate genomic variations across hundreds or even thousands of accessions in the post-genomic era. The management and exploration of these large-scale genomic variations heavily rely on programming and command-line environments, which are challenging and time-consuming for most experimental biologists and plant breeders. Here, we present BnaSNPDB, an interactive web portal with a user-friendly interface that provides multiple analysis modules for retrieving, analyzing, and visualizing single nucleotide polymorphisms among 1,007 accessions of worldwide rapeseed germplasm. It is compatible, extendable, …

Critically Appraised Topic: Hippotherapy Intervention For School Age Children With Autism Spectrum Disorders, Jedekiah May, Delanie Vitosh, Karleen Vonkrosigk

Critically Appraised Topics

The prevalence of autism spectrum disorders (ASD) has risen nearly 600 percent in the past two decades, with estimates suggesting that 1 in 68 children worldwide have a clinical diagnosis (Centers for Disease Control and Prevention [CDC], 2014). Children with ASD experience resultant challenges in occupational functioning due to impairments in communication, social interaction, and sensory processing. Sensory modulation issues can cause negative impacts on physical and social functioning. Modulation allows filtering of irrelevant stimuli and maintenance of an optimal level of arousal that facilitates attention to environmental demands with longer engagement in tasks (Llambias, Magill-Evans, Smith, & Warren, 2016). …

The Gut-Brain Axis: Treating Depression Through Microbiome Alterations, Alexandria Bachman-Williams

Physician Assistant Scholarly Project Posters

• The purpose of this study is to explore the role of gut microbiome alterations in the treatment of anxiety and depression. • There are multiple pathological pathways that lead to the development of anxiety and depression. • Research shows a link between pathologic bacteria and low grade inflammation. This causes a disruption of neurotransmitters that are current targets of pharmacological treatment of depression and anxiety. • Transfer of “pathogenic” bacteria caused increased symptoms of anxiety and depression. • Treatment with probiotics and “protective” bacteria showed decreased BDI scores and improved symptoms. • Studies were small but show need for …

The Effects Of Initiating Metformin, To Prevent Or Delay Type Ii Diabetes, In Patients With Prediabetes, Kelsey K. Abraham, Jeanie Mchugo

Physician Assistant Scholarly Project Posters

The purpose of this literature review is to explore metformin’s role in the treatment of patients with prediabetes within the primary care setting. The efficacy of metformin versus lifestyle modifications will be compared as well as metformin, as adjunctive therapy, to lifestyle modifications. Along with efficacy, a systematic analysis will examine the three above mentioned therapies regarding diabetes risk reduction. Lastly, this review will examine the safety and tolerability of metformin, specifically in patients with prediabetes. The data presented shows evidence that lifestyle modifications are first line treatment for prediabetes while metformin use should be reserved for those who fail …

Use Of Marijuana In Those With Anxiety And Depression, Heather Flaa

Physician Assistant Scholarly Project Posters

The purpose of this research and literature review was to compare the use of marijuana to SSRIs in reducing anxiety and depression symptoms.

• This literature review searched databases Cochrane, PubMed, Clinical Key, PsycINFO, and DynaMed Plus from the year 1990 and on. Keywords: cannabis, marijuana, anxiety, generalized anxiety disorder, depression, and selective serotonin reuptake inhibitors.

• Many meta-analyses show SSRIs continue to be first line treatment in those with anxiety and depression in reducing symptoms.

• Patients with marijuana use showed an increased odds ratio of developing anxiety and depression or increasing symptoms in several studies.

• No studies …

Comparison Of Anterior Cruciate Ligament Graft Materials And Risk Of Rupture/Reinjury In Young Athletes, Matt Hockert

Physician Assistant Scholarly Project Posters

The anterior cruciate ligament tear is a standard surgical injury seen with young athletes competing at elite, amateur, and recreational capacities. The purpose of this literature review is to determine the rehabilitation guidelines and risks associated with anterior cruciate ligament reconstruction, as well as determining the role of rehabilitation in graft rupture. This literature review also serves to determine if graft choice for surgical repair plays a role in an increased risk of rupture or reinjury. This literature review used various online databases, including Dynamed, Cochran, and PubMed, with the utilization of MeSH terms listed below in “keywords” in order …

Cannabis Effectiveness On The Motor Symptoms Of Parkinson’S Disease, Austin Fridrich

Physician Assistant Scholarly Project Posters

Fueled by news media reports, cannabis use has been ever growing in popularity for the treatment of both motor and non-motor symptoms of Parkinson’s disease (PD). The purpose of this literature review is to evaluate the safety and efficacy of using cannabis to treat the motor symptoms and levodopa-induced dyskinesia of PD. In this literature review electronic databases were searched and included PubMed, CINAHL, Embase, DynaMedPlus, Cochrane Library, Academic Search Premier, and Clinical Key. A variety of keywords and mesh terms, as listed below, were used to define a set of literature. There were 16 studies chosen for review that …

Catheter Ablation Of The Accessory Pathway In The Asymptomatic Patient With Wolff-Parkinson-White, Erin B. Mondry

Physician Assistant Scholarly Project Posters

The purpose of this research and literature review was to analyze the safety and efficacy associated with invasive catheter ablation of the accessory pathway, in comparison to risk of sudden cardiac death and malignant arrythmias in non-ablated, asymptomatic individuals with Wolff-Parkinson-White (WPW). In this review, five databases were searched including CINAHL, Clinical Key, PubMed, Cochrane Library, and Dynamed Plus. Both keyword and mesh terms were used to define a set of the literature discussing Wolff-Parkinson-White, ventricular preexcitation, radiofrequency catheter ablation, and sudden cardiac death. Works chosen for review were published from 2009 to 2019, and included surveys, case control studies, …

Mat Effectiveness For Oxycodone Vs Heroin In Opioid Use Disorders, Casey Myklebust

Physician Assistant Scholarly Project Posters

Opioid use disorder is a major epidemic in the United States. • Rural areas suffer the most with limited resources available for treatments options. • A limited number of providers participate in MAT programs due to a negative stigma. • Project Echo was developed to spread awareness and information about MAT to educate providers and healthcare facilities about the needs of opioid use disorder patients that are not being met. • Buprenorphine, naltrexone, and methadone are the FDA approved medications to assist in MAT. • Medication assisted treatment is a long-term commitment to successfully maintain sobriety. • Medication alone is …

Hpv Vaccine In Adolescents: How To Increase Uptake, Natasha Richsesin

Physician Assistant Scholarly Project Posters

The human papillomavirus (HPV) is a sexually transmitted virus that affects both males and females of all ages. An HPV vaccine was created to help protect against harmful infections caused by the virus.

• This literature review focuses on the relationship between the HPV vaccine and its low uptake from untoward events, misinformation surrounding the vaccine, and different education methods. PubMed, Clinical Key, and Cochrane electronic databases are used for the literature review. A comprehensive literature review was conducted, and articles utilized were based on the age of the population being 11 to 29 years old, the HPV vaccine’s involvement …

Methamphetamine: Potential Risk Factor For Neurodegenerative Conditions, Katelyn Sarlette

Physician Assistant Scholarly Project Posters

Methamphetamine use is a relevant problems in many communities. While it has many adverse health effects, it may also contribute to the development of the neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson’s disease (PD).

• A literature review was conducted using PubMed, EMBASE, Clinical Key, and DynaMed. Literature found included high quality systematic reviews, randomized controlled trials, and meta-analysis.

• Literature supports that METH use has several major neurotoxic effects resulting in physical and cognitive deficits. There is minimal available evidence evaluating METH use as a risk factor for ALS although, they do share …

Low-Dose Naltrexone For Treatment In Crohn’S Disease And Fibromyalgia, Hannah R. Tkach

Physician Assistant Scholarly Project Posters

The United States has experienced a dramatic increase in opioid abuse and overdoses, leading to a national epidemic. Contributing to this epidemic is the use of opioid therapy for complex chronic inflammatory and neuropathic conditions that remain difficult to treat. Many traditional treatments are ineffective or have intolerable side effects, forcing providers to utilize opioid therapy as a last resort. Recently, there is increased interest in the use of partial opioid antagonist naltrexone to treat Crohn’s disease and fibromyalgia. Previous research suggests the potential for naltrexone to provide analgesic effects when administered in low doses via its unique interaction with …

The Effects Of A Clinical Coaching Education On Clinical Faculty’S Coaching Behaviors, Kara L. Kaldawi

Walden Dissertations and Doctoral Studies

New graduates’ readiness to provide safe nursing care is a goal of nursing programs and employers. However, new graduate nurses do not always have the skills to make decisions in the clinical setting during a patient situation, which can result in poor patient outcomes. But clinical coaching is a faculty teaching framework that promotes the development of clinical reasoning through the deliberate practice of questioning and feedback after a patient situation. Thus, the purpose of this study was to determine whether participation in a clinical coaching education program improved the coaching behaviors of clinical nurse educators. Knowles’ theory of adult …