Medicine and Health Sciences Commons^™

An Unusual Cause Of Proximal Thigh Pain: Focal Dystonia Of The Psoas, James J. Bresnahan, Md, Mitchell H. Paulin, Md

Department of Rehabilitation Medicine Posters

Case Description

• 68-year old female presented for evaluation of right groin pain.
• The pain in her groin radiated superiorly to the lower abdomen and inferiorly to the anteromedial aspect of the proximal thigh and was ongoing for >8 years
• Physicians seen: Neurosurgery, Orthopaedics, Pain Management
• Testing: MRI L-Spine showing degenerative changes and no significant neuroforaminal or spinal stenosis.
• Treatments: PT, multiple epidural steroid injections, facet joint injections, medial branch blocks, and a spinal cord stimulator trial

Machine Learning For The Preliminary Diagnosis Of Dementia, Fubao Zhu, Xiaonan Li, Haipeng Tang, Zhuo He, Chaoyang Zhang, Guang-Uei Hung, Pai-Yi Chiu, Weihua Zhou

Faculty Publications

Objective: The reliable diagnosis remains a challenging issue in the early stages of dementia. We aimed to develop and validate a new method based on machine learning to help the preliminary diagnosis of normal, mild cognitive impairment (MCI), very mild dementia (VMD), and dementia using an informant-based questionnaire.

Methods: We enrolled 5,272 individuals who filled out a 37-item questionnaire. In order to select the most important features, three different techniques of feature selection were tested. Then, the top features combined with six classification algorithms were used to develop the diagnostic models.

Results: Information Gain was the most …

Adolescent Interventions To Manage Self-Regulation In Type 1 Diabetes (Aims-T1d): Randomized Control Trial Study Protocol., Alison L Miller, Sharon L Lo, Dana K. Albright Phd, Joyce M Lee, Christine M Hunter, Katherine W Bauer, Rosalind King, Katy M Clark, Kiren Chaudhry, Niko Kaciroti, Benjamin Katz, Emily M Fredericks

Health Services and Informatics Research

BACKGROUND: Self-regulation (SR), or the capacity to control one's thoughts, emotions, and behaviors in order to achieve a desired goal, shapes health outcomes through many pathways, including supporting adherence to medical treatment regimens. Type 1 Diabetes (T1D) is one specific condition that requires SR to ensure adherence to daily treatment regimens that can be arduous and effortful (e.g., monitoring blood glucose). Adolescents, in particular, have poor adherence to T1D treatment regimens, yet it is essential that they assume increased responsibility for managing their T1D as they approach young adulthood. Adolescence is also a time of rapid changes in SR capacity …

Gut Microbial Protein Expression In Response To Dietary Patterns In A Controlled Feeding Study: A Metaproteomic Approach, Sheng Pan, Meredith A J Hullar, Lisa A Lai, Hong Peng, Damon H May, William S Noble, Daniel Raftery, Sandi L Navarro, Marian L Neuhouser, Paul D Lampe, Johanna W Lampe, Ru Chen

Faculty, Staff and Students Publications

Although the gut microbiome has been associated with dietary patterns linked to health, microbial metabolism is not well characterized. This ancillary study was a proof of principle analysis for a novel application of metaproteomics to study microbial protein expression in a controlled dietary intervention. We measured the response of the microbiome to diet in a randomized crossover dietary intervention of a whole-grain, low glycemic load diet (WG) and a refined-grain, high glycemic load diet (RG). Total proteins in stools from 9 participants at the end of each diet period (

Development And Testing Of Novel Antimicrobial Materials For Additive Manufacturing With Application In Space, Michael Thompson, Jorge Zuniga, Christopher Copeland, Roberto Saavedra, Claudia Cortes Reyes, Andres Acuña Velásquez, Daniel Martínez Pereira, Claudio Soto

UNO Student Research and Creative Activity Fair

PURPOSE: The purpose of the study was twofold: (i) develop and test the antimicrobial properties of a polylactic acid- and a polyurethane-based filament, and (ii) use these filaments to manufacture a socket-based prosthesis to verify printability and longevity of the antimicrobial properties. It was hypothesized that the formulation of a novel biocidal copper-based nanocomposite with a biocompatible 3D printing polymer/copolymer can be used for the development of antimicrobial medical devices to mitigate microbial risks during long space flight missions [1, 2, 3].

METHODS: Polylactic Acid-based Filament Development-The development of a polylactic acid-based filament involved several processes, such as fermentation …

Pharmacist-Prescribed Birth Control: A Policy Analysis, Brianna Full

UNO Student Research and Creative Activity Fair

Although unintended pregnancy in the United States has steadily decreased from 2008, rates are still unacceptably high as almost half (42%) of all pregnancies are not wanted or timed correctly (Finer & Zolna). In 2011, 2.8 million of the 6.1 million pregnancies in the United States each year were unintended. Public health professionals are worried about unintended pregnancy because research shows that unwanted or mistimed pregnancies come with associations to adverse maternal and child health outcomes, such as delayed prenatal care, premature birth, and negative physical and mental health effects for children (Frost, Frohwirth & Zolna, 2016). Also, two-thirds (68%) …

Psycho-Physiological Reactions To Automated Leadership, Seth Hackleman

UNO Student Research and Creative Activity Fair

We all remember the 2008 Disney Pixar film Wall-E. This amazing children’s movie highlights the relationship between two robots and a human pilot on a mission to save the planet. Advances in artificial intelligence and computer technology are enabling new and exciting opportunities for humans to interact with machines. Where humans often change jobs or inevitably retire, machines can be employed for lifetimes. This fact makes them prime candidates for replacing human leaders in some circumstances to avoid the knowledge loss that can occur when a human leader changes position or no longer works in an organization. While human-to-human leadership …

Characterization Of Dimerization Domains On The Mannose-6-Phosphate/Insulin-Like Growth Factor 2 Receptor, Tyler Degener

UNO Student Research and Creative Activity Fair

The mannose-6-phosphate/insulin-like growth factor 2 (M6P/IGF2) receptor is a transmembrane protein with the ability to sequester growth factors from the extracellular matrix. This behavior links the receptor to tumor suppression. On a structural level, the extracellular portion of the protein is segmented into 15 homologous repeats, which can be divided further into 5 triplet domains, labelled 1-3, 4-6, 7-9, 10-12, and 13-15. Each triplet receptor displays its own unique ligand binding affinity, including the ability to form dimers with triplets on a second M6P/IGF2 receptor. In fact, previous studies indicate that this protein functions optimally when dimerized. Thus, the purpose …

Utilizing Chemical Mutagenesis To Determine U21 Mechanism Of Action In Toxoplasma Gondii, Andrew Pham

UNO Student Research and Creative Activity Fair

The abstract has been removed to protect intellectual property of the project.

Longitudinal Analysis Of Gait In People With Parkinson’S Disease To Improve The Detection Of Risk Of Falls, Ryan Meidinger

UNO Student Research and Creative Activity Fair

Within 3 years of diagnosis, more than 85% of people with Parkinson’s disease (PD) develop gait problems, which may lead to falls resulting in serious injury and reduced quality of life. The evolution of gait impairments with PD progression and the relationship between locomotor performance and falls in PD are unclear. In addition, large individual variations exist at the level of gait performances corresponding to specific levels of disease severity. Deficits in cognitive and sensory-motor functions in PD also impair the ability to walk while doing another task (i.e., dual-tasking). When attentional resources in PD patients are allocated to more …

Translating National Standards Into Practice: Supporting Social Care Professionals, Victoria O'Dwyer, Laura Behan, Linda Weir, Deirdre Connolly, Rachel Flynn

Journal of Social Care

The Health Information and Quality Authority [HIQA] was established in 2007 to drive high quality and safe care for people using health and social care services in Ireland. One of the functions of HIQA is to set national standards for services. When developing standards HIQA conducts a thorough review of evidence and extensively engages stakeholders through focus groups, advisory groups and public consultations. To validate the robustness of its processes HIQA distributed a survey to key stakeholders with experience of the standards development processes in 2018. It also undertook an international review of how other organisations approach the development of …

Impacts Of Mitoquinol Mesylate Intake On Vascular Function And Cognitive Impairment In Patients With Mild Cognitive Impairment: A Case Study, Lindie Strickler

UNO Student Research and Creative Activity Fair

Mild cognitive impairment (MCI) is a decline in cognitive function to a greater extent than natural aging. It has been suggested that reduced brain blood flow is strongly associated with reduced cognitive function and neurodegenerative diseases, of which is partially attributed to excessive reactive oxygen species (ROS) production. Mitoquinol mesylate has been shown to scavenge ROS and improve vascular function in healthy older adults. However, the effects of mitoquinol in MCI patients have not been investigated.

Purpose: to elucidate the impacts of mitoquinol intake on vascular endothelial function (flow-mediated dilation, FMD), arterial stiffness (pulse-wave velocity, PWV), and cognitive function in …

Lessons Learned From Designing A Health Monitoring System To Improve First Responders Safety User Interface, Janaki Devi Naveena Akula, Jackson Urrutia, Hitesh Kumar Khatri, Anusha Manda, Jacob C. Grothe

UNO Student Research and Creative Activity Fair

Every day, first responders put their own lives at risk to help individuals, families, and communities. They experience many safety and health hazards on the front-line that can lead to injuries, chronic illnesses, and even death. Chronic illnesses include cancer, heart diseases, and behavioral health issues that often cause first responders life expectancy to be significantly shortened.

According to the National Fire Protection Association, there were 64 on-duty firefighter deaths in 2018. Sudden cardiac death accounted for about 40% of the on-duty fatalities. During 2017, there were an estimated 44,530 documented exposures to hazardous conditions (e.g. chemicals, fumes, radioactive materials) …

Comparison Of Eye Gaze Behaviors Across Samples Of 8- And 9-Month-Old Infants At-Risk For Autism, Aaron Borcyk, Sarah Schmidt, Hannah Lopez, Shari Deveney, Anastasia Kyvelidou

UNO Student Research and Creative Activity Fair

Though a precise etiology for autism remains unknown, two infant populations present with particularly high risk: younger siblings of children diagnosed with autism and infants born prematurely with low birth weight. The aim of the present exploratory study was to determine differences in social and nonsocial eye gaze behaviors between two samples of 8­ and 9­-month infants from high ­risk groups.

Review Of Aging-Related Changes To The Neuroendocrine System And Implications For Older Caregivers, Nicholas Miller

UNO Student Research and Creative Activity Fair

This abstract has been removed to protect the intellectual property of the project.

Quantitative Analysis Of Sexual Function In Women Up To 1-Year Postpartum, Amber Kelly

UNO Student Research and Creative Activity Fair

Background. Sexual satisfaction is a strong predictor of relationship satisfaction and a component of general well-being. Changes in sexual behavior are common during pregnancy and the subsequent transition to parenthood. Currently, little literature exists that examines the breadth of factors contributing to decreased female sexual functionality during the postpartum period. Identifying factors associated with decreased female sexual function following childbirth has the potential to improve postpartum women’s sexual satisfaction and overall quality of life. The study seeks to answer the following research questions: RQ 1: What impact has childbirth had on frequency of sexual activity in women within the first …

Comparing Individual Perceptions Of Food Desert With Quantitative Measures In Omaha, Nebraska., Hector N. Samani, Bradley Bereitschaft

UNO Student Research and Creative Activity Fair

Food deserts have been linked to an increase in chronic diseases such as obesity and diabetes, due to lower access to affordable and healthy foods. The United States Department of Agriculture (USDA) outlines various methods and variables for defining food deserts, in attempts to standardize what constitutes a food desert or their characteristics. The USDA identifies the state of Nebraska as having both rural and urban food deserts, with an increase of food insecurity from 1.1% – 3.0% between 2007 and 2012 and warns of further increase of food deserts and its impact if measures are not taken. However, there …

Unintended Pregnancy Among The Lgbtq+ Population, Kenna M. Barnes

UNO Student Research and Creative Activity Fair

Unintended births are related to adverse health outcomes for both parents and children (Mosher, et al., 2012). For the context of this research, unintended will include both mistimed (too early) and unwanted (wanted to avoid pregnancy) pregnancies. Non-heterosexual women, defined as anyone who has same-sex sexual behaviors, attractions, or identities, make up about 5.1% of the population according to Williams Institute (2019). The impact of unintended pregnancy among non-heterosexual individuals is not well understood, creating large disparities in the community. This has manifested in emotional, physical, and social wellness gaps compared to their heterosexual counterparts (Buchmueller & Carpenter, 2010; Everett …

Relationship Between Movement Quality, Functional Ambulation Status, And Spatiotemporal Gait Parameters In Children With Myelomeningocele., Megan Flores, Kathleen Manella, Elizabeth Ardolino

Physical Therapy Collection

Aims: We investigated relationships among the Pediatric Neuromuscular Recovery Scale (Peds NRS), modified Hoffer Scale, and spatiotemporal gait parameters in children with myelomeningocele (MMC).

Methods: 21 children with MMC, age 5.3 years (SD = 2.6), were assessed by three clinicians using the Peds NRS and modified Hoffer Scale. In eight children, gait parameters were also measured.

Results: The Peds NRS summary score demonstrated good correlation with modified Hoffer Scale score (r = -0.64, p = 0.002) that accounted for 41% of variation in summary score. Six Peds NRS seated/standing items exhibited good relationships with modified Hoffer Scale …

Metastatic Spinal Cord Compression Mimicking Cauda Equina Syndrome Illustrating Importance Of Adequate Diagnostic Imaging, Jonathan L. Holt, Joseph Hill, Farzin Farhandnejad, Karyn Doddy, Se Won Lee

Physical Medicine & Rehabilitation

See additional files.

Rehabilitation Following Valproic Acid-Induced Hyperammonemic Encephalopathy (Vhe) In A Patient With Intractable Epilepsy, Dan Nguyen, Ann Ikonne, Sewon Lee, Mark Steinhauer

Physical Medicine & Rehabilitation

See additional documents.

Worsening Weakness After Posterior Cervical Decompression And Fusion; The Challenge In Diagnosis, Steven D. Kim, Joseph Hill, Farzin Farhandnejad, Karyn Doddy

Physical Medicine & Rehabilitation

See additional files.

Unmasking Severe Hypotension After Intermittent Catheter For Distended Bladder In A Patient With Cervical Spinal Cord Injury, Dennis Nguyen, Neal Ekpoudia, Ellsworth Remson, Farzin Farhandnejad, Se Won Lee

Physical Medicine & Rehabilitation

See additional files.

How One Library’S Location Change Impacted Health Information Requests: Comparing Zip Codes And Health Disparities To Inform Library Services: Data Files, David Petersen, Martha Earl, Cameron Watson, Kelsey Grabeel

Faculty Publications

No abstract provided.

Covid-19 Clinical Guidance For The Cardiovascular Care Team, Thomas M. Maddox, Eric C. Stecker, Biykem Bozkurt, Nathalie Demichelis, John U. Doherty, Andrew Freeman, Tyler J Gluckman, Dipti Itchhaporia, Andrew P. Miller, Andrea L. Price, Lonny Reisman, Prem Soman, Mohammad Madjid, Scott D. Solomon, Orly Vardeny

Articles, Abstracts, and Reports

COVID-19 is a quickly evolving public health emergency. The guidance provided in this document is based on the best available published information and expert evaluation. This document is intended to supplement, not supersede, relevant guidance from the Centers for Disease Control and Prevention, state and local health authorities, and your institution’s infectious disease containment, mitigation, and response plan.

Inhibition Of Radiographic Progression Across Levels Of Composite Index-Defined Disease Activity In Patients With Active Psoriatic Arthritis Treated With Intravenous Golimumab: Results From A Phase-3, Double-Blind, Placebo-Controlled Trial., Philip Mease, M Elaine Husni, Shelly Kafka, Soumya D Chakravarty, Diane D Harrison, Kim Hung Lo, Stephen Xu, Elizabeth C Hsia, Arthur Kavanaugh

Articles, Abstracts, and Reports

BACKGROUND: In the GO-VIBRANT trial of intravenous golimumab in psoriatic arthritis (PsA), golimumab significantly inhibited radiographic progression. In post hoc analyses, we evaluated changes in total PsA-modified Sharp/van der Heijde scores (SHS) across levels of composite index-defined disease activity following treatment.

METHODS: In this phase-3, double-blind, placebo-controlled trial, 480 bio-naïve patients with active PsA randomly received intravenous golimumab 2 mg/kg (N = 241; week 0, week 4, every 8 weeks [q8w]) or placebo (N = 239; week 0, week 4, week 12, week 20) followed by golimumab (week 24, week 28, q8w) through week 52. Week 24 and week 52 …

From The Provost: Summer Study Abroad Programs, March 6, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from the Provost announcing the cancellation of study abroad classes for the summer of 2020.

Therapeutic Potential Of Citrulline As An Arginine Supplement: A Clinical Pharmacology Review, Jahidur Rashid, Shaun S. Kumar, Kathleen M. Job, Xiaoxi Liu, Candice D. Fike, Catherine M. T. Sherwin

Pediatrics Faculty Publications

Supplemental arginine has shown promise as a safe therapeutic option to improve endogenous nitric oxide (NO) regulation in cardiovascular diseases associated with endothelial dysfunction. L-arginine, an endogenous amino acid, was reported in clinical studies in adults to improve cardiovascular function in hypertension, pulmonary hypertension, pre-eclampsia, angina, and mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome. L-citrulline, a natural precursor of L-arginine, is more bioavailable than L-arginine because of hepatic first-pass metabolism avoidance and longer circulation time. Although not yet well studied, arginine/citrulline has immense therapeutic potential in some life-threatening diseases of children. However, optimal clinical development of arginine or …

Osteoma Cutis, Lehigh Valley Health Network

Posters

No abstract provided.

Behind The Scenes Of Starting A New Residency Program, Traci Wooden, Krystal D. Hernandez, Elizabeth Rashid

Medical Education

During this workshop, we will split up the stages of building a new program into the following- Stage 1, Stage 2 and Stage 3. Stage 1 will focus on applying for initial accreditation, gathering faculty and sites, the first recruitment season, building/creating a curriculum, program planning and the first full cycle of GME including match, onboarding, orientation, CCC/PEC, wellness and more. Stage 2 will focus on more program planning, including building a new clinic, building electives, adding faculty, faculty development, continued accreditation site visit, building a senior curriculum and chief resident selection. Stage 3 will discuss board prep and board …