Medicine and Health Sciences Commons^™

Tea Tree Oil Acne Treatments On Pinterest: Will It Save Your Face?, Madison Hoggarth, Hannah Goepfert, Sarah Whitney

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: The power of social media has defined many aspects of modern society and provides easy access to healthcare information. Specifically, Pinterest with more than 320 million monthly users provides a platform to share both product examples and homemade remedies. Acne affects between 40 to 50 million people in the U.S. causing physical irritation and emotional distress. Essential oils, especially tea tree oil, have shown antibacterial properties in acne treatment but proper application and use is critical.

Purpose: In this study, the portrayal of tea tree oil as an acne treatment on Pinterest and its efficacy as a topical acne …

Insights From The Influx Of Prescription Painkillers In Northeast Florida: A Retrospective Analysis, Joseph Free, Michelle Dedeo

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

The opioid epidemic has had, and will have, long-lasting ramifications in the United States. To better understand its impact in the Northeast Florida, this research seeks to identify relationships between hydro- and oxycodone pill concentration at the county and zip code levels and socio-economic factors such as average adjusted gross income and opioid related mortality. This project utilizes time series, regression, and GIS methods to examine local opioid saturation and has led to the development of an interactive Tableau dashboard which allows users to view opioid saturation at various levels of granularity. This analysis is made possible by longitudinal data …

Not All Fruits And Vegetables Are Equal: Colors Of Fruits And Vegetables And Diabetes Risk In The U.S. Latino Population, Raymond Colon, Zhiping Yu

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Objectives: Fruits and vegetables (FV) play an important role in people’s health. The current study aimed to identify if specific colors of FVs are associated with type 2 diabetes (DM) risk in the United States Hispanic/Latino population.

Methods: This study used a subgroup of participants from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). This is a multi-center, prospective cohort study with 16,415 self-identified Hispanic/Latino individuals from 2008-2011. Data collected include anthropometrics, OGTT, dietary intake, medical history, physical activity, and sociodemographic information. FVs are categorized into five color groups: green, white, yellow/orange, red/purple, and uncategorized.

Results: Total 5,740 participants (ages …

The Influence Of Bias With Mental Health Counselors And Cisgender Men Wearing Makeup, Brandi Velasquez Nash

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

The concepts of gender & sexuality within counselor diversity training continue to expand & change over time; therefore, it is essential that mental health professionals are knowledgeable of the changes faced by gender non-conforming (GNC) individuals, specifically cisgender men who wear makeup. This includes being aware of the biases and stigmas that GNC individuals face and understanding how those barriers affect their mental health.

Elements that are applicable to this population include: (a) the historical significance & implications of cisgender men who wear makeup, (b) social media platforms where cisgender men showcase their makeup skills, (c) cultural experiences of GNC …

Portrayal Of Nuclear Energy On Twitter, Seth Gozar, Alex Justice, Moon Ja, Tammy Cao

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: With more than 300 million active users, Twitter has become a platform to consume and share political rhetoric and popular science opinion. With long-held concerns of nuclear disasters, radioactive waste, and economic sustainability, nuclear energy is a particularly polarizing topic on Twitter.

Purpose: This study used directed content analysis to examine how nuclear energy is portrayed on Twitter, a popular social media microblogging website.

Methods: Using the search terms “nuclear energy” and “nuclear power,” researchers sampled tweets in the “Top” category, skipping 25 non-relevant tweets, for a total of 400 relevant tweets. A codebook was developed, pilot tested, and …

Unique Bodies, Unique Stories: Exploring The Mental Health Experiences Of Intersex Individuals, Courtney Boggs, Hannah Glusenkamp, April Jones, Terry Kirton, Faith Ponti, Cortney Surrency, Tes Tuason Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

There is between 1 in 1,500 and 1 in 2,000 intersex births per year. The term intersex refers to infants born with genitalia that are not definitively male or female (“How common is intersex?,” n.d.). Though a relatively common birth condition, great societal and familial secrecy surrounds the issue of intersex conditions (Danon, 2019; Meoded-Danon & Yanay, 2016). Research shows that this secrecy, along with medical trauma from corrective and maintenance surgeries and confusion about one’s body and identity, can cause long-term mental health struggles among intersex individuals and their caretakers (Danon, 2019; Meoded-Danon & Yanay, 2016; Schweizer et al, …

Visibility Of Whiteness: Analyzing White Privilege Among Female Counseling Trainees, Caitlyn Murtha, Tes Tuason

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Interracial dialogues about racial issues are often accompanied by anger, anxiety and guilt. For example, the notion of Whiteness as a privileged status frequently provokes strong negative affect and denial in White persons (Sue, David Rivera, Capodilupo, Lin, & Torino, 2010; Powell, Branscombe, & Schmitt, 2005). McClelland and Linnander (2006) found that interpersonal contact is an important factor in changing racial attitudes among White counseling trainees. The current study sought to examine white female counseling trainees’ written reflections following a personal one-on-one dialogue with culturally different interviewees. Seventeen graduate counseling trainees who self-identified as White and were enrolled in a …

Determining Glioblastoma Proteome Changes In Response To Lateral Ventricle Neural Stem Cells, Lauren Whaley, Emily S. Norton, Natanael Zarco, Hugo Guerrero-Cazares

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Glioblastoma (GBM) is the most common and malignant primary tumor in adults. When GBM tumors are located close to the lateral ventricle they display a more aggressive recurrence pattern and negatively impact patient survival. These findings suggest the involvement of the subventricular zone neurogenic niche in GBM malignancy. To define the inter-cellular communication between neural stem cells and GBM cells, we optimized a tool to determine cell-specific proteomic changes of GBM cells in response to neural stem cell proximity.

We cloned the mutated methionyl-tRNA synthetase (MetRS) gene into the lentiviral plasmid MetRS puro. MetRS allows for incorporation of azide-tagged methionine …

2020-04-08 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Bismuth-Based Nanomaterials: Recent Advances In Tumor Targeting And Synergistic Cancer Therapy Techniques, Samireh Badrigilan, Jalal Choupani, Hashem Khanbabaei, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Despite all of the efforts in the field of cancer therapy, the heterogeneous properties of tumor cells induce an insufficient therapeutic outcome when treated with conventional monotherapies, necessitating a shift in cancer treatment from monotherapy to combination therapy for complete cancer treatment. Multifunctional bismuth (Bi)-based nanomaterials (NMs) with therapeutic functions hold great promise for the fields of cancer diagnosis and therapy based on their low toxicity, X-ray sensitive capabilities, high atomic number, near-infrared driven semiconductor properties, and low cost. Herein, a comprehensive review of recent advances in various medicinal aspects of Bi-based NMs is presented including: evaluation of in-tumor site …

The Tipping Point In Psychopathy: Role Of Psychopathic Traits In Trauma Exposure, Sneha M. Gupta

Student Theses

Though psychopathy has been associated with a socially deviant lifestyle, the idea of “successful” psychopathy has gained increased attention. Previous research has explored whether psychopathic traits play a role in trauma exposure/ PTSD, using clinical and forensic populations. Results from these studies suggest that Factor 1 traits may protect from trauma exposure (Factor 1 Theory) while Factor 2 traits may worsen the impact of trauma through exacerbated exposure to traumatic events. The objective of this study was to explore the relationship between each of Factor 1 traits and Factor 2 traits with trauma exposure and PTSD. In a sample of …

High Supervised Resistance Training In Elderly Women: The Role Of Supervision Ratio, Denis Cesar Leite Vieira, Dahan Da Cunha Nascimento, Vitor Tajra, Tatiane Gomes Teixeira, Darlan Lopes De Farias, Ramires Tibana, Alessandro Oliveira Silva, Thiago Santos Rosa, Milton Rocha Moraes, Fabrício Azevedo Voltarelli, James W. Navalta, Jonato Prestes

Kinesiology and Nutrition Sciences Faculty Research

The objective of this study was to compare the effects of very high supervision (VHS-RT) versus high supervision (HS-RT) ratio resistance training (RT) on irisin, brain-derived neurotrophic factor (BNDF), muscle strength, functional capacity, and body composition in elderly women. Participants performed daily undulating periodized RT over 16 weeks with two different supervision ratios: VHS-RT at 1:2 (supervisor/subject) or HS-RT at 1:5. Serum was used to analyze brain derived neurotropic factor (BDNF) and irisin by enzyme-linked immunosorbent assay (ELISA). Body composition was evaluated by dual-energy X-ray absorptiometry, while functional capacity was evaluated using the Six-minute walk test, and Timed Up and …

Aerodynamic Measurement Stability During Rabbit Versus Pig Benchtop Phonation, Megan Caroline Hoggan

Theses and Dissertations

Combination corticosteroid inhalers are the primary treatment option for long-term pulmonary disorders including asthma, persistent bronchitis, and chronic obstructive pulmonary disease. Common side effects of these medications are xerostomia in the mouth and throat, hoarseness, and soreness in the oropharynx. Research indicates that a large percentage of the inhaler particles are deposited onto laryngeal tissue, leaving an alteration of laryngeal mucosal properties. As the first stage in a long-term project, this thesis addresses the need for baseline phonatory data that will lay groundwork for quantifying inhaler-induced phonatory changes. Excised larynx research is a powerful tool for assessing aerodynamic alterations that …

Comorbidity Factors Influence Covid-19 Mortality Much More Than Age, Steven Gjerstad, Andrea Molle

ESI Working Papers

This paper demonstrates that once we control for comorbidity factors, age has a minor effect on COVID-19 mortality. This has implications for the treatment of current and recovered COVID-19 patients, including health screenings of recovered COVID-19 patients, triage decisions for patients in critical care, and prioritization of vaccinations when one is developed. The coronavirus epidemic in Italy has strained hospital resources, including ICU beds and ventilators for those experiencing acute respiratory failure. Studies of COVID-19 in China [1], Italy [2], and the United States [3] show that fatality rates increase rapidly with age, especially beyond age 60. The same studies …

Terfezia Boudieri: A Desert Truffle With Anticancer And Immunomodulatory Activities, Maha Farid Al Obaydi, Wafaa M. Hamed, Lina T. Al Kury, Wamidh H. Talib

All Works

© Copyright © 2020 Al Obaydi, Hamed, Al Kury and Talib. Desert truffles have high nutritional value and grow wild in the Mediterranean basin and Western Asia. Although, many studies were performed to evaluate truffles nutritious values and phytochemical composition, studies are limited to evaluate their anticancer and/ or immunomodulatory effects. Our study was conducted to evaluate the anticancer and immunomodulatory effects of Terfezia boudieri (desert truffle). Different solvent extracts were prepared from the truffle and MTT assay was used to measure their anticancer activity against cancer cell lines (T47D, MCF-7, MDA-MB231, HCT-116, and Hela). Total phenolic content in each …

Safe Consumption Facilities As Harm Reduction, Christina Jäderholm, Dana Crossby, Rachel Greim, Chelsea Peterson, Dawn Richardson

OHSU-PSU School of Public Health Annual Conference

Overview/Issue

Substance use disorder (SUD) is one of the largest public health challenges in Oregon, with approximately 1-in-10 Oregonians living with SUD and some experiencing overdose annually. Safe Consumption Facilities (SCF) have been shown to facilitate entry into treatment programs and prevent fatal overdoses and needle sharing, but have not yet been implemented.

Challenges

SCFs have succeeded in Canada and Europe; yet several barriers exist to implementation in the U.S. The most common challenges include: low public support and a lack of understanding regarding SUD and harm reduction strategies; limited funding and research in the United States; and the complexities …

Defining Stress Among Oregon Corrections Professionals, Jessica T. Ballin

OHSU-PSU School of Public Health Annual Conference

Corrections professionals experience some of the highest levels of chronic stress compared to other occupations. This leads to poor mental and physical health, increased mortality, negative job performance, and increased economic costs, such as work-related injuries, sick leave, worker’s compensation claims and disability. Improving health and safety among this occupation requires identifying the factors contributing to stress and the associated economic impact. We assessed corrections professionals (n=296) working at six different Oregon Department of Corrections facilities near the Portland-area of varying security levels. Participants completed a cross-sectional survey, including demographics, work history and validated stress and occupational constructs. The outcome …

Water 4.0, Arthur Preston

OHSU-PSU School of Public Health Annual Conference

A review of local drinking water quality/technologies, and strategies to improve water quality using emerging next generation technology.

National Death Rates From Firearms Due To Legal Intervention For Native Americans, Hanrui Huang

OHSU-PSU School of Public Health Annual Conference

According to the CDC, deaths from legal intervention are defined as deaths caused by injuries inflicted by law enforcement officers. Although some studies have examined high rates of fatal legal intervention shootings among African Americans, rates for Native Americans have not been adequately examined, despite similar racial biases and stereotypes. This study aims to examine national data and examine the association of fatal legal intervention shootings and Native communities.

The available data provided on legal intervention (CDC) was studied to understand death rates for different races. The data was then analyzed to examine changes over time between 2008 and 2018. …

The Epidemiology Of Firearm-Related Injuries Presenting At The Two Level-1 Trauma Centers In Oregon From 2009-2019, Kamil Narayan, Kathleen F. Carlson, Susan Defrancesco

OHSU-PSU School of Public Health Annual Conference

Injury is an important clinical and public health problem worldwide. Firearm-related injury is an important source of trauma-related morbidity and increases the risk of death. The CDC reports that in 2017, 74.5% of homicides deaths and 50.6% of suicide deaths were caused by firearms. The purpose of our retrospective chart review is to describe the epidemiology of firearm-related injuries presenting in the emergency department of two level-1 trauma centers in Oregon over a 10-year period. The study involves victims of gunshot injuries of all ages who were treated in the OHSU and Legacy Emanuel Emergency Department during the calendar years …

Associations With Early Intervention Evaluation, Eligibility, And Services Engagement In A Multi-Site Sample, Mohadeseh Solgi, Katharine Zuckerman, Alicia Feryn

OHSU-PSU School of Public Health Annual Conference

TITLE: Associations with Early Intervention Evaluation, Eligibility, and Services Engagement in a multi-site sample

Background: Parental concerns are usually highly predictive of child developmental delays; however, the relationship of parent concerns with Part C Early Intervention (EI) service use is unclear.

Objective: The goals of this project were to test the associations of parent concern presence, age of child at time of parent concerns, number of concerns, type of parental concern, and recency of parental concerns, with EI evaluation, eligibility, and services engagement after referral.

Design/Methods: We collected survey data on parent concerns, EI service use data, and family demographics …

Structure, Function And Metabolism Of Hepatic And Adipose Tissue Lipid Droplets: Implications In Alcoholic Liver Disease, Sathish Kumar Natarajan, Karuna Rasineni, Murali Ganesan, Dan Feng, Benita L. Mcvicker, Mark A. Mcniven, Natalia A. Osna, Justin L. Mott, Carol A. Casey, Kusum K. Kharbanda

School of Veterinary and Biomedical Sciences: Faculty Publications

For more than 30 years, lipid droplets (LDs) were considered as an inert bag of lipid for storage of energy-rich fat molecules. Following a paradigm shift almost a decade ago, LDs are presently considered an active subcellular organelle especially designed for assembling, storing and subsequently supplying lipids for generating energy and membrane synthesis (and in the case of hepatocytes for VLDL secretion). LDs also play a central role in many other cellular functions such as viral assembly and protein degradation. Here, we have explored the structural and functional changes that occur in hepatic and adipose tissue LDs following chronic ethanol …

Important Commencement Information, April 7, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from the Office of the Registrar to graduating students about options for commencement.

2020-04-07_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Histidine-Triad Hydrolases Provide Resistance To Peptide-Nucleotide Antibiotics., Eldar Yagmurov, Darya Tsibulskaya, Alexey Livenskyi, Marina Serebryakova, Yury I Wolf, Sergei Borukhov, Konstantin Severinov, Svetlana Dubiley

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The Escherichia coli microcin C (McC) and related compounds are potent Trojan horse peptide-nucleotide antibiotics. The peptide part facilitates transport into sensitive cells. Inside the cell, the peptide part is degraded by nonspecific peptidases releasing an aspartamide-adenylate containing a phosphoramide bond. This nonhydrolyzable compound inhibits aspartyl-tRNA synthetase. In addition to the efficient export of McC outside the producing cells, special mechanisms have evolved to avoid self-toxicity caused by the degradation of the peptide part inside the producers. Here, we report that histidine-triad (HIT) hydrolases encoded in biosynthetic clusters of some McC homologs or by standalone genes confer resistance to McC-like …

Osteopathy And The Pandemic Of 1918, Robyn Oro

Notes from the Archives

No abstract provided.

2020-04-07 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Balance Of Adults With Chronic Ankle Instability Following A 6-Week Core Stability Program, Natalie Dickol

Theses and Dissertations

Ankle injuries are one of the most common injuries in the athletic population because of the anatomy of the ankle in conjunction with dynamic activity. During injury, mechanoreceptors are damaged, effecting neuromuscular control. Lack of neuromuscular control puts patients at risk for re-injury. Chronic ankle instability (CAI) has been defined as a condition associated with recurrent sprains and persistent symptoms, including feelings of "giving way," loss of function and limited movement and continuous ankle pain. Patients with CAI are commonly shown to have functional deficits in postural control, such as overcompensating on the uninvolved limb or unable to maintain proper …

A Mutation-Specific, Single-Arm, Phase 2 Study Of Dovitinib In Patients With Advanced Malignancies., Matthew H Taylor, Ajjai S Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A Piha-Paul

Articles, Abstracts, and Reports

BACKGROUND: Receptor tyrosine kinases (RTKs) play key roles in tumorigenesis. The multi-RTK inhibitor dovitinib has demonstrated promising antitumor activity in multiple cancers.

PATIENTS AND METHODS: In this phase 2, open-label, single-arm study, patients with advanced malignancies with RTK-pathway genetic aberrations whose disease progressed on/following standard treatment received dovitinib (500 mg/day; 5-days-on/2-days-off). The primary endpoint was clinical benefit rate (CBR; complete response, partial response [PR], or stable disease [SD] for ≥ 16 weeks).

RESULTS: Of 80 patients enrolled, common tumors included gastrointestinal stromal tumors (GIST; 20.0%), colorectal cancer (CRC; 18.8%), and ovarian cancer (10.0%). Patients were heavily pretreated (median prior lines …

Lived Experiences With Inauthenticity Of The Physician Assistant Program Admission Essay: A Phenomenological Study, Pollyanna Kabara

CUP Ed.D. Dissertations

Inauthenticity occurs in the physician assistant program admission process when students plagiarize content of the admission essay. This qualitative research study focused on the experiences of physician assistant admission committee members with the admission process, including the experiences of physician assistant admission committee members with the authenticity of the admission process. The experience with the components of the admission process were discussed through eight interviews with physician assistant admission committee members from accredited physician assistant programs in the United States. Phenomenology was the research method used to evaluate the experience the admission committee members have had with the components of …