Covid-19 Journal | Kristy Finley, Kristy Finley

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Emmalie Lovett, Emmalie Lovett

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Jesalyn Pettit, Jesalyn Pettit

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Cassidy Riddle, Cassidy Riddle

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Ebony Scott, Ebony Scott

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Taylor Thicklin, Taylor Thicklin

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Ashton Whiteside, Ashton Whiteside

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Gavin Anderson, Gavin Anderson

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Demetrius Martin, Demetrius Martin

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Journal | Pita Leandro, Pita Leandro

COVID-19 Student Journal Project

No abstract provided.

Covid-19 Assignment Details, Christopher Bishop

COVID-19 Student Journal Project

No abstract provided.

2020-05-01 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

The Discovery Of Metarhizium Anisopliae (Metchnikoff) Sorokin Isolates From Arkansas And Their Pathogenicity To Amblyomma Americanum L., Austin Goldsmith

Graduate Theses and Dissertations

The lone star tick Amblyomma americanum L. is the most abundant tick in Arkansas and has been implicated as a vector of many important disease-causing pathogens. Many species of entomopathogenic fungi have been isolated from several species of ticks, with some of these fungi being utilized for tick biocontrol. However, few studies have assessed the pathogenicity of entomopathogenic fungi to A. americanum. The objectives of this study were to: isolate and identify native Arkansas isolates of entomopathogenic fungi from wild A. americanum ticks exposed to soil and to compare the pathogenicity of one isolate (Metarhizium anisopliae (Metchnikoff) Sorokin isolate Savoy …

Transformation Leadership And Youth Development Soccer Coaches: Behaviors That Enhance Coaching Performance, Diego Barros Dos Santos

Leadership Education Capstones

This quantitative study investigated the potential relationship between youth development soccer coaching style and transformational leadership behaviors. An anonymous survey was the source of data for this study. Participants responses were categorized into the four factors of transformational leadership which include (1) intellectual stimulation, (2) inspirational motivation, (3) idealized influence, and (4) individualized considerations. Recommendations for future research encompass expanding the demographics, sample size and field observations. Additionally, further research could include a contrast and comparison between coaches perspective x athletes perspective about transformational leadership behaviors. Furthermore, transformational leadership workshop and post survey intervention might expose how coaches leadership style …

Video Modeling And Occupational Engagement In Individuals With Autism Spectrum Disorder, Teresa Le, Brianna Rodrigues, Katherine Blankenship, Gabrielle Ann Tabije, Cassandra Marshall

Occupational Therapy | MSOT Capstone Projects

Introduction

Autism spectrum disorder (ASD) impacts a variety of occupations (Hong et al., 2016). Occupational therapy (OT) intervention is essential for promoting occupational engagement for individuals with ASD. One way in which occupational therapists can promote engagement is through assistive technology (AT). Video modeling (VM) is an evidence-based practice (EBP) for individuals with ASD that falls under the umbrella of AT (Franzone & Collet-Klingenberg, 2008). VM capitalizes on the visual learning strengths of individuals with ASD and minimizes the use of auditory processing, which is an area of relative weakness (Campbell et al., 2015). Motor planning tends to be an …

Renal Transplantation In A Patient With Mhy9-Related Disease; A Case Report, Sepideh Zununi Vahed, Bahram Niknafs, Hamid Noshad, Ramin Tolouian, Mohammadali Mohajel Shoja, Audrey C. Tolouian, Mohammadreza Ardalan

Nursing Faculty Publications

MYH9-related diseases (MYH9-RD) are clinically represented by thrombocytopenia, large platelets, proteinuria and various degrees of renal dysfunction. We present a 25-year-old male with thrombocytopenia, large platelets, renal dysfunction and proteinuria. Gene sequencing of whole exons of MYH9 gene confirmed the diagnosis of MYH9-related disorder and revealed single nucleotide polymorphisms (SNPs) in the introns 13 (rs3752462) and 14 (rs2413396) and a mutation in exon 26 of MYH9 gene. Our result supported the possibility of non-coding SNPs involvement in the pathogenicity of the MYH9-RD disease and successful renal transplant in this patient.

The Footprint Of Androgen Sensitive Serine Protease (Tmprss2) In Gender Mortality With Covid-19, Sepideh Zununi Vahed, Shahram Ghiyasvand, Ramin Tolouian, Hamid Noshad, Audrey C. Tolouian, Mohammadali Mohajel Shoja, Mohammadreza Ardalan

Nursing Faculty Publications

Male gender is an obvious risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and mortality rate is higher in men than women. Undoubtedly, gender-related behavioral factors, such as higher amounts of smoking, alcohol consumption, and biological differences in immune systems could make males more vulnerable. The role of androgen-responsive elements (AREs) of transmembrane serine proteases type II (TMPRSS2) gene as one of the major players of male dominancy in severe COVID-19 infection has been under appreciated and needs to be clarified.

The Impact Of Metformin In Chronic Kidney Disease-Mineral And Bone Disorder, Rohollah Masumi, Ramin Tolouian, Audrey C. Tolouian, Leila Mohmoodnia

Nursing Faculty Publications

Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a disorder of mineral and bone metabolism due to chronic kidney disease (CKD). Bone disease and mortality are more common in patients with CKD. In addition of antidiabetic properties of metformin (MET), it possesses anti-inflammatory, anti-fibrotic properties and increases the markers of osteogenic effects. Therefore, it improves bone quality and decreases the risk of fractures in patients with type 2 diabetes. Metformin can also inhibit arterial calcification, maintain calcium-phosphorus balance, decrease cellular infiltration, fibrosis, and inflammation in kidney. Based on evidence, the prevalence of lactic acidosis due to metformin in patients with …

The Impact Of A Faith-Based Education Network For Cardiovascular Disease Prevention, Chandila Tutt

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Abstract

Cardiovascular disease is a leading cause of mortality in the United States. Racial disparities related to cardiovascular disease also exist, especially in African Americans. It is imperative to explore solutions to close the gap among these individuals. This study measured the effectiveness of an educational intervention on cardiovascular disease prevention targeting African Americans in a faith-based community setting. This study aimed to target individuals in community and faith-based settings for health promotion and disease prevention through an education network, increase participant’s awareness and knowledge about cardiovascular disease, determine the impact of a cardiovascular disease program on perceived cardiovascular disease …

Lack Of Osteopontin Induces Systolic And Diastolic Dysfunction In The Heart Following Myocardial Ischemia/Reperfusion Injury, Caytlin James

Undergraduate Honors Theses

Ischemic heart disease is a leading cause of death worldwide. Osteopontin (OPN), a cell-secreted extracellular matrix protein, is suggested to play a cardioprotective role in mouse models of ischemic heart disease. The objective of this study was to examine the role of OPN in modulation of systolic and diastolic functional parameters of the heart following mouse ischemia/reperfusion (I/R) injury. For this, wild-type (WT) and OPN-knockout (KO) mice aged approximately 4 months were subjected to cardiac ischemia for 45 minutes by the ligation of the left anterior descending coronary artery (LAD) followed by reperfusion of LAD by snipping the ligature. Heart …

Effects Of Nicotinamide Riboside And Beta-Hydroxybutyrate On C. Elegans Lifespan, Jeffery Peters

Undergraduate Honors Theses

The nicotinamide riboside (NR) form of vitamin B₃and the ketone body ß-hydroxybutyrate (BHB) are two of the most promising natural compounds yet identified for the treatment of aging and aging-related diseases. Forms of vitamin B₃are precursors for the synthesis of the coenzymes nicotinamide adenine dinucleotide (NAD(H)) and nicotinamide adenine dinucleotide phosphate (NADP(H)). In aged cells levels of NAD⁺decline, decreasing metabolism and decreasing activity of protective sirtuin protein deacetylases. In aged cells NR, but not more common forms of vitamin B3, boost NAD⁺levels. BHB is naturally produced by the body when individuals fast …

Levels Of Parp1-Immunoreactivity In The Human Brain In Major Depressive Disorder, Aamir Shaikh

Undergraduate Honors Theses

MDD is a severe and debilitating disorder that is associated with a growing global economic burden due to reduced workplace productivity along with increased healthcare resource utilization. Furthermore, depression markedly enhances the risk for suicide, mortality that is especially worrisome given that 30% of depressed individuals have an inadequate response to current antidepressants. This inadequacy of antidepressants necessitates the discovery of a better understanding of the pathobiology of MDD. Most current antidepressants work through monoamine neurotransmitters, and their relative efficacy in depression led to the now dated monoamine-deficiency hypothesis. The limited usefulness of antidepressants has led to a reinvigorated search …

A Study Of The Polymicrobial Inhibitory Interactions Between Alcaligenes Faecalis And Staphylococcus Aureus, Blakeley Griffin

Undergraduate Honors Theses

Members of the Staphylococcus genus are found as a part of normal microflora in humans and can commonly be found on the skin or in the nasal cavity. However, these microorganisms can cause serious and life-threatening opportunistic infections when there is a break in the physical barrier of skin. These infections have become difficult to treat as resistant strains emerge, particularly Methicillin Resistant Staphylococcus aureus (MRSA). MRSA has become a commonly acquired nosocomial infection which is difficult to treat with conventional antibiotics of the blactam class. Even Vancomycin, a last resort antibiotic, has been ineffective on some infections. Furthermore, …

Polysubstance Exposure And Its Relationship To Pharmacological Treatment Characteristics, Parker Miller

Undergraduate Honors Theses

Neonatal Abstinence Syndrome (NAS) remains an ever-growing public health issue and a continued avenue for future research. The research question for this retrospective study was whether polysubstance exposure is related to the dose of medication the infant received or to the number of opioid-medications required to treat the infants’ withdrawal symptoms? The hypothesis for the retrospective study was there will be a significant relationship between polysubstance exposure and the dose of medication the infant received as well as the number of opioid-medications required to treat the infants’ withdrawal symptoms. A bivariate correlational indicated that there was not a significant association …

Gut Pathophysiology In Mouse Models Of Social Behavior Deficits, Kyla Scott

Undergraduate Honors Theses

Autism spectrum disorders (ASD) encompass neurodevelopment disorders characterized by atypical patterns of development that impact multiple areas of functioning beginning in early childhood. The etiology of ASD is unknown and there are currently no preventative treatment options. Gastrointestinal symptoms are commonly associated comorbidities. The microbiota-gut-brain axis is a multidirectional communication chain that connects the central and enteric nervous system that relates brain function to peripheral intestinal functions. Changes within this axis have been postulated in ASD. For example, the “leaky gut theory” proposes that chronic inflammation is linked to alterations in the bacterial profiles of the gut microbiome and subsequent …

Social Participation In College Students With Chronic Pain, Megan Chamberlain, Megan Chinn, Jennifer Pineda, Camille Santiago, Jamie Spitzer, Patricia Tran

Occupational Therapy | MSOT Capstone Projects

College students with chronic pain often experience difficulty engaging in social activities both on and off campus due to stigma, misconceptions, or social exclusions (Culp & Rojas-Guyler, 2014). To fully understand the barriers to social engagement, the researchers used a qualitative phenomenological approach and semi-structured interviews to explore the lived experiences of 15 college students with chronic pain (pain lasting more than six months). Four main themes were identified: the additional influence of personality on social participation; stigma and lack of understanding of chronic pain; the “domino effect” of pain impacting energy, sleep quality, and ability to function throughout the …

Interrelationship Between Sensory Modulation, Altered Interoceptive Awareness, And Anxiety And Impacts On Quality Of Life, Sara Laughter, Vanessa Mitchell, Natalie Nguyen, Christine Kim

Occupational Therapy | MSOT Capstone Projects

OBJECTIVE: The negative impacts of sensory modulation disorder (SMD), anxiety, and altered interoceptive awareness (AIA) on daily occupations reinforced the need for the study of the relationship between sensory modulation, anxiety, and interoception in typical adults. Understanding the relationship between the three constructs is the first step in the ultimate goal of developing effective intervention and treatment measures.

METHODS: This cross-sectional, exploratory study analyzed the relationship between scores on four self-report measures in an online survey: State Trait Anxiety Inventory (STAI), 36-Item Short Form Health Survey (SF-36), Sensory Responsiveness Questionnaire (SRQ), and Multidimensional Assessment of Interoceptive Awareness, Version 2 (MAIA-2). …

Fostering Humanization: Providing Care In The Margins, Alicia Mccauley

Theses and Graduate Projects

This doctorate of nursing practice project aimed to restore or improve the physical, emotional, and spiritual health in the marginalized population in Rochester, Minnesota to promote human dignity and foster humanization through the opening of a nursing-led drop-in center. Guided by􏰈 Jean Watson􏰆s Theory of Human Caring, the Rochester Health Commons was opened and provided personal hygiene supplies, foot soaks, foot care, community resources, and most importantly offered a place for people to feel welcomed and cared for. Utilizing the concepts of transpersonal caring, authentic listening, mutuality, and radical hospitality, transcultural nursing students serving at the Rochester Health Commons reduced …

Creating Health Membership In A Health Commons, Melinda Dively-White

Theses and Graduate Projects

Persons living in the margins may be separated or isolated because of poverty, disability, gender, and ethnicity. Isolation, along with exposure to at-risk environments and barriers to accessing health care, contributes to adverse health outcomes. Nurses must be open to learning essential transcultural skills to work with persons living in the margins to provide culturally appropriate care that addresses health inequities. Students in a Doctor of Nursing Practice program at Augsburg University developed an innovative approach to care for people living in the margins. The Health Commons, a nursing-led drop-in center in Rochester, MN, and grounded in Newman's (1999) Health …

Effect Of Diabetes Mellitus On Ocular Surface Tight Junctions And Glycocalyx, Saleh M. Alfuraih

Pharmaceutical Sciences (MS) Theses

Introduction: Diabetes mellitus is the disease of the century that affects many body organs. In the eye, diabetes mellitus causes retinopathy, cataract, glaucoma, papillopathy, and ocular surface disease. Ocular surface abnormalities in patients of diabetes mullites include impairment of corneal epithelial barrier function, conjunctival defects, increased incidence of corneal and conjunctival infections and higher prevalence of dry eye disease. Impairment of tight junctions and glycocalyx, which are critical for ocular surface barrier function, may underlie these diabetes-associated ocular surface defects. Therefore, the present study was designed to investigate the effect of high glucose exposure and type I diabetes mellitus on …