Medicine and Health Sciences Commons^™

Relationship Between Performance Tests And Yard Per Carry Average In Collegiate Running Backs, Jason Kyle Newsom

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science at Morehead State University in partial fulfillment of the requirements for the Degree Master of Arts by Jason Kyle Newsom on April 24, 2017.

Perceptions Of The Body Haunted: An Analysis Of Significant Pilot Study Findings On The Abuse And Harassment Of Women With Disabilities Ho Chi Minh City, Vietnam, Pia C. Mingkwan

International Studies Honors Projects

This pilot study conducted with Disability Research and Capacity Development in Ho Chi Minh City, Vietnam, found that women with disabilities (WWD) reported significant experiences with abuse and harassment. Analysis of these findings revealed that the abuse and harassment of WWD is directly connected to the complex roles that gender and disability hold within Vietnamese society. Vietnam is a patriarchal society and WWD experienced abuse and harassment due to their roles as women; their expressions of gender and sexuality in connection with disability; and their desire for participation in processes such as sex, intimacy, and childbearing. Additionally, disabled bodies in …

Persistent Neurobehavioral Traits In A Mouse Model Of Prenatal Ethanol Exposure, Jill M. Lawrence

Neuroscience Honors Papers

Fetal Alcohol Spectrum Disorders (FASD) effect an estimated 2% of the population, causing a range of symptoms: from craniofacial defects to inhibited cortical growth (May, et al., 2009; Murawski, et al., 2015). Impaired medial forebrain function apparent in FASD is associated with lifelong cognitive behavioral deficits, but these consequences may be avoided with early diagnosis and intervention (Streissguth, et al., 2004). Our goal is to identify early neurobehavioral abnormalities that persist into adulthood that could potentially serve as early indicators for FASD. Mouse models of prenatal ethanol exposure were developed using a voluntary drinking paradigm that introduced a sweetened ethanol …

The Malaria Testing And Treatment Landscape In Mainland Tanzania, 2016., Kathryn A. O'Connell, Vamsi Vasireddy, Megan Littrell, Andria Rusk, Actwatch Group, Daniel Michael, Sigsbert Patila Mkunde

Collected Faculty Scholarship

BACKGROUND: Understanding the key characteristics of malaria testing and treatment is essential to the control of a disease that continues to pose a major risk of morbidity and mortality in mainland Tanzania, with evidence of a resurgence of the disease in recent years. The introduction of artemisinin combination therapy (ACT) as the first-line treatment for malaria, alongside policies to promote rational case management following testing, highlights the need for evidence of anti-malarial and testing markets in the country. The results of the most recent mainland Tanzania ACTwatch outlet survey are presented here, including data on the availability, market share and …

What's Happening: April 24, 2017, Maine Medical Center

What's Happening

No abstract provided.

Examination Of Neurocorrelates Of Mild Traumatic Brain Injury In Young Adults, Rachel J. Raucci

Neuroscience Honors Papers

In recent years, there has been an upswing in the number of concussion diagnoses per year in the United States, particularly in young athletes with still-developing brains. Accompanying this recent trend is an increased amount of research on concussions and their long-term impacts. This ongoing research project collects and compares data from concussed and non-concussed individuals using various neuropsychological batteries, self-report surveys and participants’ EEG readings. Data analysis of the results from 51 participants indicates that previously concussed individuals differ from their non-concussed counterparts. Specifically, individuals who have suffered a concussion exhibit specific and occasionally idiosyncratic deficits in executive control …

Nucleic Acid Combinations: A New Frontier For Cancer Treatment, K. C. Remant Bahadur, Bindu Thapa, Juliana Valencia-Serna, Hamidreza Montazeri Aliabadi, Hasan Uludağ

Pharmacy Faculty Articles and Research

The emerging molecular understanding of cancer cell behavior is leading to increasing possibilities to control unchecked cell growth and metastasis. On the other hand, development of multifunctional drug carriers at the ‘nano’-scale is providing exciting new therapeutic strategies in clinical management of cancer beyond the conventional cytotoxic drugs. A new frontier in this regard is the combinational use of complementary agents based on nucleic acids to overcome the limitations of conventional therapy. The existence of tightly-integrated cross-talk through multiple signaling and effector pathways has been appreciated for some time, and the plasticity of such a network to overcome one-dimensional intervention …

East Meets West: Cultural Values And Duty To Care For Disaster Response, Tracy J. Nash

Nursing Theses and Dissertations

Nurses’ readiness for disaster response has assumed front and center-stage in recent years, due to the heightened number of natural and human-induced disasters across the globe. Scientific literature affirms that without nurses’ personal and professional readiness for disaster situations, patient and public health outcomes will likely decline. Three research manuscripts presented in this dissertation portfolio targeted this significant, but overlooked public health issue. First, a quantitative pilot study addressing nurses’ personal preparedness for disaster response was considered. Findings from the study not only justified personal readiness as a significant concept, but also prompted review of the scientific literature to further …

Aromatase Inhibitors And Bone Loss Prevention Independent Case Study Report, Lori Loomis

Nursing Capstones

No abstract provided.

Functional Human Grin2b Promoter Polymorphism And Variation Of Mental Processing Speed In Older Adults, Yang Jiang, Ming Kuan Lin, Gregory A. Jicha, Xiuhua Ding, Sabrina L. Mcilwrath, David W. Fardo, Lucas S. Broster, Frederick A. Schmitt, Richard J. Kryscio, Robert H. Lipsky

Behavioral Science Faculty Publications

We investigated the role of a single nucleotide polymorphism rs3764030 (G > A) within the human GRIN2B promoter in mental processing speed in healthy, cognitively intact, older adults. In vitro DNA-binding and reporter gene assays of different allele combinations in transfected cells showed that the A allele was a gain-of-function variant associated with increasing GRIN2B mRNA levels. We tested the hypothesis that individuals with A allele will have better memory performance (i.e. faster reaction times) in older age. Twenty-eight older adults (ages 65-86) from a well-characterized longitudinal cohort were recruited and performed a modified delayed match-to-sample task. The rs3764030 polymorphism was …

Week Of April 24, 2017, New York Medical College

InTouch

• SHSP Celebrates National Public Health Week
• Camille A. Clare, M.D., M.P.H. '11, Named Associate Dean of Diversity and Inclusion for the School of Medicine
• Sarah Cottet Named Acting Director of the Department of Facilities

Trading Pounds For Points: Engagement And Weight Loss In A Mobile Health Intervention, Sarah Hales, Gabrielle Turner-Mcgrievy, Sarah Wilcox, Rachel Davis, Arjang Fahim, Michael N. Huhns, Homayoun Valafar

Faculty Publications

Abstract Objective The objective of this study was to describe participant engagement and examine predictors of weight loss and points earned through the point-based incentive system of the Social Pounds Off Digitally (POD) app.

Materials and methods Overweight and obese adults with Android smartphones/tablets (body mass index 25–49.9 kg/m2; N = 24) were recruited for a 3-month weight loss intervention. Participants completed a survey assessing demographics and personality and had their weight measured. Participants received the content of the intervention via podcasts and used the Social POD app to self-monitor diet, physical activity, and weight. The Social POD app contained: …

Role Of Modern Immunotherapy In Gastrointestinal Malignancies: A Review Of Current Clinical Progress, Zin W. Myint, Gaurav Goel

Markey Cancer Center Faculty Publications

Gastrointestinal (GI) cancers are a group of highly aggressive malignancies with a huge disease burden worldwide. There is clearly a significant unmet need for new drugs and therapies to further improve the treatment outcomes of GI malignancies. Immunotherapy is a novel treatment strategy that is emerging as an effective and promising treatment option against several types of cancers. CTLA-4 and PD-1 are critical immune checkpoint molecules that negatively regulate T cell activation via distinct mechanisms. Immune checkpoint blockade with antibodies directed against these pathways has already shown clinical efficacy that has led to their FDA approval in the treatment of …

Health Benefits Of A Plant-Based Diet, Jenna Jackson

Honors Theses

While the rise and spread of Western culture has created remarkable advances in science, healthcare, and technology, it has also brought about a variety of chronic diseases that never once existed. Much of these ailments can be attributed to the typical Western diet, which places heavy emphasis on meats, dairy, and refined grains, contrasting the typical Eastern or Oriental diet which primarily focuses on fruits, vegetables, fish, and whole grains. This dietary transition has resulted in increased glycemic load, increased levels of unhealthy fats and cholesterol, decreased micronutrient and fiber levels, and skewed acid-base and sodium-potassium ratios. All of these …

Behavioral Sex Difference In Healthy Sprauge-Dawley Rats, Jeffrey Bagg, Jessica Obie, Fei Shang, Natalie Lista, Corinne Kiessling

Binghamton University Undergraduate Journal

Recently, the NIH has pushed for both sexes of a species to be incorporated into behavioral experiments. This push came as a result of an unchecked exclusion of females in experimentation. In rat studies, it is a common argument that females are more variable than males due to the presence of their estrous cycle. This study set out to evaluate this claim, and provide sex differences data for a variety of motor, anxiety, and cognitive behavioral tests. No sex differences in motor or anxiety behavior were found between the sexes. Males performed significantly better on the spontaneous alternation test of …

Developing A Guideline Driven Provider-To-Provider Handoff Tool For Heart Failure Patients, Nicole Dellise

DNP Projects

The American Heart Association (AHA) and Heart Failure Society of America’s (HFSA) guideline for Management of Heart Failure in Skilled Nursing Facilities acknowledged poor communication from hospitals to skilled nursing facilities (SNF) as a barrier to optimal heart failure (HF) management. The purpose of this pilot study was to improve adherence to guideline directed HF care in SNFs through enhanced communication between hospital HF specialists and providers at SNFs. The project leader designed a guideline driven provider-to-provider HF handoff tool. Twenty-one patient discharges were evaluated in the study. Follow up phone calls were made to SNF staff nurse within 48 …

Proper Prescribing Of Controlled Drugs: A Pilot Study Of A Web-Based Learning Modules’ Impact On Knowledge, Attitude, And Practice In New Graduate Nurse Practitioners, Shelly Duckett

DNP Projects

Controlled substance abuse is a global epidemic. Several factors that influence health care providers prescribing habits have been presented in recent literature. However, the existing evidence primarily reflects the prescribing habits of physicians, while relatively little is known about the prescribing habits of nurse practitioners. The purpose of this project is to evaluate the impact of a brief web-based continuing education module targeting appropriate prescribing of controlled substances for recent graduate nurse practitioners. The project served to assess the provider’s knowledge, attitude, and practice compared to current integrated curriculum on prescribing and assess change in knowledge. Two online educational modules …

Psychotherapy Is Chaotic— (Not Only) In A Computational World, Günter K. Schlepek, Kathrin Vol, Wolfgang Aichhorn, Marc-Thorsten Hütt, Katharina Sungler, David Pincus, Helmut J. Schöller

Psychology Faculty Articles and Research

Objective: The aim of this article is to outline the role of chaotic dynamics in psychotherapy. Besides some empirical findings of chaos at different time scales, the focus is on theoretical modeling of change processes explaining and simulating chaotic dynamics. It will be illustrated how some common factors of psychotherapeutic change and psychological hypotheses on motivation, emotion regulation, and information processing of the client’s functioning can be integrated into a comprehensive nonlinear model of human change processes.

Methods: The model combines 5 variables (intensity of emotions, problem intensity, motivation to change, insight and new perspectives, therapeutic success) and …

Medical School Watercooler Newsletter - April 23, 2017, Lindsey Lyle

Watercooler Newsletter

This is the April 23, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Dr. Stephen Kayes Honored with Retirement Reception

USA Resident, Faculty and COM Alum Collaborate for 2017 SAGES Annual Meeting

Medical Students Express Gratitude to Donor Families at Anatomical Gifts Memorial Service

Students and Faculty to be Honored at Annual Honors Convocation

Pharmacodynamic Activity Of Fosfomycin Simulating Urinary Concentrations Achieved After A Single 3 Gram Oral Dose Versus Escherichia Coli Using An In Vitro Model, George G. Zhanel, Kate Parkinson, Sean Higgins, Andrew Denisuik, Heather Adam, Johann Pitout, Ayman Noreddin, James A. Karlowsky

Pharmacy Faculty Articles and Research

We assessed the activity of fosfomycin simulating urinary concentrations achieved after a single 3 gram oral dose against Escherichia coli using an in vitro pharmacodynamic model. Eleven urinary isolates of E. coli were studied. Isolates were ESBL-producing or carbapenemase-producing. The in vitro pharmacodynamic model was inoculated with an inoculum of (~1 × 10⁶ cfu/mL). Fosfomycin was administered to simulate maximum free (ƒ) urine (U) concentrations and a t_1/2 obtained after a standard single 3 gram oral dose in healthy volunteers (ƒU_max, 4000 mg/L; t_1/2, 6 h). Sampling was performed over 48 h to assess …

Grounded Theory And The Conundrum Of Literature Review: Framework For Novice Researchers, Mohamed T. El Hussein, Andrea Kennedy, Brent Oliver

The Qualitative Report

The issue of the literature review remains a conundrum and a controversy within the discourse on grounded theory methodology. Grounded theory researchers are expected to minimize preconceptions to ensure the concept of interest is grounded in data, yet at the same time are required to evaluate existing literature to support institutional ethics and scientific review of the research proposal. In addressing this dilemma, we espouse that literature review in grounded theory should comprise a multistage nonlinear approach to the literature and introduce a framework for novice grounded theory researchers. This framework offers a reflexive, dynamic and integrative process for conducting …

Mexicans In The U.S And Hiv: Reviewing Social And Cultural Factors, Eduardo Alvarez

Annual Undergraduate Conference on Health and Society

Mexican immigrants in the United States continue to struggle with disproportionate incidences of HIV infection. Behaviors that contributed to the development of AIDS among Mexican immigrants were the lack of condom use, engaging in risky sexual behavior, and not having HIV testing (Martínez Donate, et al., 2015). While these risk factors are preventable, religious and social stigmatization present within the Mexican community generate shame and embarrassment. This discourages Mexican immigrants from seeking health services, such as HIV testing. An estimated 20% of HIV positive Mexican immigrants are unaware of their condition, and contribute to the spread of the virus (Hall …

Point Of Care Technology For Underserved Populations, Anna Maloney

Annual Undergraduate Conference on Health and Society

Point of Care technology is an emerging healthcare field. This technology allows for rapid, inexpensive, on-site testing for otherwise lengthy and costly laboratory tests. Leading infectious diseases can be tested immediately in non-invasive ways similar to using a pregnancy test. This inexpensive, highly portable, and extremely accurate technology should be used for populations that have historically lacked access. Such access would result in immediate cost savings and life savings.

Underserved populations in America such as migrant workers or people living in poverty rarely receive the testing they require. Although clinics for illegal immigrants exist where they are protected and cannot …

Nurse Faculty Orientation: Building Confidence And Professional Development, Melissa Zwisler

Nursing Capstones

No abstract provided.

Repeat After Me: Dance Program Evaluation For The Friendship Circle, Michelle Sire

Honors Projects

Approximately 1 in 6 children in the United States are diagnosed with one or more developmental disabilities or delays (Boyle et al., 2011). Although the number of therapeutic approaches for children with developmental disabilities has increased, no single treatment or combination of treatments is effective in relieving symptoms for all individuals (Scharoun, Reinders, Bryden & Fletcher, 2014). Therefore, there is a need to continue to explore alternative therapeutic methods. Research over the past twenty years has found dance/movement therapy (DMT) to be an effective form of treatment for children with special needs, specifically in terms of functioning and well-being. However, …

Estimating The Impact Of A Select Criteria Pollutant (Pm2.5) On Childhood Asthma In Florida, Shabnam Mehra

USF Tampa Graduate Theses and Dissertations

Asthma has been reported in children as a leading chronic illness in the US and around the world. It is also the third leading cause of hospitalization among children under the age of 15, and is also one of the most common causes of school absenteeism. Children are at higher risk of asthma attacks and they pose a higher burden on health care system. Nearly 20.6% of middle and high school children in Florida have been told they have asthma, this prevalence has grown over 3% from 2006 to 2012. Changes in air pollutant levels are often related to health …

Keep Calm And Control Your Ulcerative Colitis, Tiara Teders

BU Well

Diet and psychological stress have positive and negative effects on ulcerative colitis (UC) exacerbations. Research conducted in regards to diet is summarized and recommendations which have been proven beneficial to avoid UC exacerbations are provided. Research regarding psychological stress in relation to UC exacerbation proves difficult to conduct, but many UC patients and gastroenterologists believe a connection exists between the two; thus, this article discusses research to help other patients with UC to avoid exacerbations and lead a more comfortable life.

Do You Have Any Questions For The Pharmacist?, Rachel Mays

BU Well

As perhaps the single-most common inquiry in modern healthcare, the question, “Do you have any questions for the pharmacist?” represents not only an integral step in pharmacy workflow, but also an excellent opportunity for healthcare consumer education. Pharmacy counseling serves as arguably the most convenient, accessible avenue for the public to gain medication-related information in an ever-busying and demanding American healthcare culture. Unfortunately, no “one size fits all” approach to pharmacy counseling exists, and delivering meaningful, effective education requires acknowledgement of a variety of patient-specific factors. This article ex­plores the utilization of Myers-Briggs Type Indicator test results to determine impactful …

Cheers To The Health Benefits Of Wine, Sarah Lenahan

BU Well

Many countries attribute their increased life expectancies and overall health to their consistent consumption of red wine. In the multimedia piece about the health benefits of wine, Mr. Hulesman discussed how consuming one to two glasses of red wine each evening is associated with a decrease in depression, increase in cardiac health, and even lower risk of cancer. While red wine is associated with the most benefits, any grape of wine in moderation is acceptable.

Crispr: The Last Piece Of The Genetic Puzzle, Brad Broyles

BU Well

CRISPR/Cas9 is an emerging gene editing tool. This technology, which evolved naturally as a defense mechanism for bacteria and other prokaryotes, has been repurposed to edit genes in a wide array of cells, including human cells. This paper outlines the discovery, mechanism, and potential applications of CRISPR/Cas9.