Medicine and Health Sciences Commons^™

Current Prospects Of Type Ii Interferon Γ Signaling & Autoimmunity, Daniel S. Green, Howard A. Young, Julio C. Valencia

United States Public Health Resources

Interferon γ (IFNγ) is a pleiotropic protein secreted by immune cells. IFNγ signals through the IFNγ receptor, a protein complex that mediates downstream signaling events. Studies into IFNγ signaling have provided insight into the general concepts of receptor signaling, receptor internalization, regulation of distinct signaling pathways, and transcriptional regulation. Although IFNγ is the central mediator of the adaptive immune response to pathogens, it has been shown to be involved in several non-infectious physiological processes. This review will provide an introduction into IFNγ signaling biology and the functional roles of IFNγ in the autoimmune response.

Environmental Health News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Georgia Southern Examines Validity of Mold Sampling Method

Slot Antenna Integrated Re-Entrant Resonator Based Wireless Pressure Sensor For High-Temperature Applications, Shujing Su, Fei Lu, Guozhu Wu, Dezhi Wu, Qiulin Tan, Helei Dong, Jijun Xiong

Publications

The highly sensitive pressure sensor presented in this paper aims at wireless passive sensing in a high temperature environment by using microwave backscattering technology. The structure of the re-entrant resonator was analyzed and optimized using theoretical calculation, software simulation, and its equivalent lump circuit model was first modified by us. Micro-machining and high-temperature co-fired ceramic (HTCC) process technologies were applied to fabricate the sensor, solving the common problem of cavity sealing during the air pressure loading test. In addition, to prevent the response signal from being immersed in the strong background clutter of the hermetic metal chamber, which makes its …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern Examines Validity of Mold Sampling Method

Research Brief: "Reproductive Health Of Active Duty Women In Medically Austere Environments", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the use of contraceptives, the unintended pregnancy rates, and birth defects among active duty servicewomen as compared to the civilian population. In policy and practice, servicewomen and female veterans should use reproductive and health services provided by local VA medical centers and discuss environmental exposures to their healthcare provider, who should conduct full exams with patients and discuss healthcare needs while the servicemembers are deployed; the DoD should look into the use of portable medical equipment and how to support all servicemembers, and policymakers may consider funding DoD programs for counseling about women's reproductive healthcare options. …

The Effects Of Perinatal Oxycodone Exposure On Behavioral Outcome In A Rodent Model, Thitinart Sithisarn, Sandra J. Legan, Philip M. Westgate, Melinda E. Wilson, Kristen Wellmann, Henrietta S. Bada, Susan Barron

Pediatrics Faculty Publications

Opiate addiction is now a major public health problem. Perinatal insults and exposure to opiates such as morphine in utero are well known to affect development of the hypothalamic–pituitary–adrenal axis of the offspring adversely and are associated with a higher risk of developing neurobehavioral problems. Oxycodone is now one of the most frequently abused pain killers during pregnancy; however, limited data are available regarding whether and how perinatal oxycodone exposure (POE) alters neurobehavioral outcomes of the offspring. We demonstrated that exposure to 0.5 mg/kg/day oxycodone in utero was associated with hyperactivity in adult rats in an open field. No significant …

Cultural Competence- Identifying Cultural Practices Upon Admission To Medical Surgical Unit., Mario Carranza Bsn-Rn, Sara Mccarthy Bsn-Rn, Courtney Rittenhouse Bsn-Rn, Ashley Silberg Bsn-Rn

Patient Care Services / Nursing

No abstract provided.

Preventing Falls By Implementing A Fall Agreement., Danielle Glen Bsn, Rn, Nicole Morin, Megan Phegley

Patient Care Services / Nursing

No abstract provided.

Earlier Urinary Catheter Removal To Promote Independent Bladder Function In Patients With Epidurals., Mallory Benjamin Bsn, Rn, Rachel Williams Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Recognizing Symptoms Of Withdrawal Through Implementation Of The Cows Scale In Adult Acute Care Settings., Maria Bermudez Rn, Bsn, Carlie Griffiths Rn, Bsn, Shannon Martin Rn, Bsn

Patient Care Services / Nursing

No abstract provided.

Nurse Resiliency In Pediatric And Picu Nurses., Ashley Divincenzo Bsn, Rn, Stephanie Pinter Bsn, Rn, Alexis Gilmore Bsn, Rn, Kendra Wetherhold Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Managing Postpartum Pain In Patients With Uncomplicated Vaginal Deliveries., Cara Marzullo Bsn Rn, Breanna Miller Bsn, Rn, Jessica Reyes Bsn Rn

Patient Care Services / Nursing

No abstract provided.

Team Building Activities: Increasing Staff Engagement., Sarah Hines Bsn, Rn, Clement Eruwayo Bsn, Rn, Kristen Purkey Bsn, Rn, Sara Kirkpatrick Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Accuracy Of Finnegan Neonatal Abstinence Scoring., Mariah Hish Bsn, Rn, Nicole Strohl Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Hydrotherapy To Decrease Pain During Labor., Natalia Azar Bsn-Rn, Gabriella Haviland Bsn-Rn, Marisa Saeger Bsn-Rn

Patient Care Services / Nursing

No abstract provided.

Scd Compliance On Observation Floors., Brittany Adler Bsn, Rn, Brianna Depalma Bsn, Rn, Katherine Henry Bsn, Rn, Rn, Madlen Vasileva Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

How Educating Nurses Can Effect Sequential Compression Device Therapy., Allister Anatalio Bsn, Rn, Courtney Deegan Bsn, Rn, Hayley Hoke Bsn, Rn, Kaitlyn Mcinerney Bsn, Rn, Amy Van Wert Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Nursing Burnout 8-Hour Shifts Vs. 12-Hour Shifts., Carol Evans Bsn, Rn, Kaitlyn Edmondson Bsn, Rn, Sarah Bramich Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Quality? Safety? Stop Being Naïve., Rana K. Zaban Do, Steven Istephan, Jonathan Serman Md

Clinical Research in Practice: The Journal of Team Hippocrates

The first day of our inpatient medicine rotation, the Emergency Department (ED) admitted a patient to a general medical floor without notifying our rounding team. We used the institution’s system improvement tracking software to draw attention to communication breakdown in the interest of patient safety. This piece illustrates how there is a prominent hierarchy in medicine; it is inherent to the framework of the way in which hospitals function. A discussion ensues with our attending physician supervisor on our patient medicine service. During this discussion, we ponder whether it is possible to impact quality and safety from our position as …

Treating Diabetic Ketoacidosis With Subcutaneous Insulin?, Marlene Aziza Azar

Clinical Research in Practice: The Journal of Team Hippocrates

The author examines the evidence for treating diabetic ketoacidosis with subcutaneous insulin vs IV insulin.

Reframing Outcome Measures For Thrombolytics In Acute Ischemic Stroke, Brandon Baker, Charles W. Kropf, Nicholus Yee, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

An informed consent conversation examining relevant research and discussing the potential benefits and harms of thrombolytic therapy in acute stroke.

It Is Not Necessary To Use Both An Ivc Filter And Anticoagulation Therapy For Severe Pulmonary Embolism, Radhika Sharma

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Mismetti P, Laporte S, Pellerin O, et al. Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism: a randomized clinical trial. JAMA. 2015;313(16):1627–1635. doi: 10.1001/jama.2015.3780

Compared To Maximal Current Management Standards, Oscillating Positive Expiratory Pressure Devices Have Not Been Shown To Improve Clinically Relevant Outcomes In Copd Patients With Acute Exacerbation, Daniel P. Noack, Gaybriel Newton

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Ambrosino N, Callegari G, Galloni C, Brega S, Pinna G. Clinical evaluation of oscillating positive expiratory pressure for enhancing expectoration in diseases other than cystic fibrosis. Monaldi Arch Chest Dis. 1995;50(4):269-275.

Anticoagulation Increases Survival In Patients With Idiopathic Pulmonary Arterial Hypertension, Marvin L. Kajy

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Olsson KM, Delcroix M, Ghofrani HA, et al. Anticoagulation and survival in pulmonary arterial hypertension: Results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA). Circulation, 2014;129(1):57-65. doi: 10.1161/CIRCULATIONAHA.113.004526

From The Editor: Context Creates Meaning For Evidence, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

Introducing "Informed Consent" manuscripts and an expanded remit for the Journal.

Long-Term Effectiveness Of The Question, Persuade, Refer (Qpr) Suicide Prevention Gatekeeper Training Program: Lessons From Missouri, Clay Litteken, Elizabeth Sale

Missouri Institute for Mental Health

Suicide in Missouri is a significant public health issue that has taken the lives of 8351 individuals over the last decade. The recognition of suicide as an imminent concern has led to the development of evidence-based prevention programs to decrease suicide-related mortality. One program, question, persuade, refer (QPR), has become the most widely-distributed gatekeeper training program in the world. This article presents both immediate and 2-year follow-up analyses of QPR trainees who work with youth, specifically examining changes in knowledge, self-efficacy, and help-giving behaviors. Results indicate both short- and long-term positive outcomes in knowledge and self-efficacy, supporting use of QPR.

Interprofessional Grand Rounds: Student Hotspotting Team 2016-2017, Caroline Komanecky, Peter Sacci, Danielle Mcfadden, Nuriya Neumann, Michaela Scotten, Melissa Murphy

Department of Occupational Therapy Posters and Presentations

No abstract provided.

Addressing Barriers To Maternal Nutrition In Low- And Middle-Income Countries: A Review Of The Evidence And Programme Implications., Justine A Kavle, Megan Landry

Prevention and Community Health Faculty Publications

Adequate maternal nutrition during the “first 1,000 days” window is critical from conception through the first 6 months of life to improve nutritional status and reduce the risk of poor birth outcomes, such as low birthweight and preterm birth. Unfortunately, many programmes have targeted implementation and monitoring of nutrition interventions to infants and young children, rather than to women during pregnancy or post-partum. A literature review was conducted to identify barriers to food choice and consumption during pregnancy and lactation and to examine how low- and middle-income countries have addressed maternal nutrition in programmes. A literature review of peer-reviewed and …

Translational Fidelity, Mistranslation, And The Cellular Responses To Stress, Kyle Mohler, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Faithful translation of mRNA into the corresponding polypeptide is a complex multistep process, requiring accurate amino acid selection, transfer RNA (tRNA) charging and mRNA decoding on the ribosome. Key players in this process are aminoacyl-tRNA synthetases (aaRSs), which not only catalyse the attachment of cognate amino acids to their respective tRNAs, but also selectively hydrolyse incorrectly activated non-cognate amino acids and/or misaminoacylated tRNAs. This aaRS proofreading provides quality control checkpoints that exclude non-cognate amino acids during translation, and in so doing helps to prevent the formation of an aberrant proteome. However, despite the intrinsic need for high accuracy during translation, …

A Protocol For The Administration Of Real-Time Fmri Neurofeedback Training, Matthew Sherwood, Emily E. Diller, Elizabeth Ey, Subhashini Ganapathy, Jeremy T. Nelson, Jason G. Parker

Neuroscience, Cell Biology & Physiology Faculty Publications

Neurologic disorders are characterized by abnormal cellular-, molecular-, and circuit-level functions in the brain. New methods to induce and control neuroplastic processes and correct abnormal function, or even shift functions from damaged tissue to physiologically healthy brain regions, hold the potential to dramatically improve overall health. Of the current neuroplastic interventions in development, neurofeedback training (NFT) from functional Magnetic Resonance Imaging (fMRI) has the advantages of being completely non-invasive, non-pharmacologic, and spatially localized to target brain regions, as well as having no known side effects. Furthermore, NFT techniques, initially developed using fMRI, can often be translated to exercises that can …