Medicine and Health Sciences Commons^™

Category 5, Michael A. Gregori (Landscape Architecture), Kelly Dutertre (Accounting), Catalina Arce Elton (Marketing), Griffin Voight (Landscape Architecture)

Nexus Maximus

Follow Elizabeth and her family through this family oriented video series which highlights topics such as preparing for a hurricane, how to help those affected by a storm and raises awareness for mental health after a natural disaster.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope …

Hope Box, Ted Thresh (Industrial Design), Erica Lomando, Monica Tabet, Delara Kiani (Industrial Design), Iiro Nurmi

Nexus Maximus

The Hope Box is a purse sized container with the main purpose of giving people hope that not all is lost. This container locks and can hold your personal valuables safely from theft or water or abrasion damage.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope …

Refugee Connects, Chintha Snow Vongsakulvong (Interior Design), John Murphy, Maria Latorre, Alejandra Hernandez

Nexus Maximus

Refuge Connects

An opportunity for Refugees Syrian refugees are in a vulnerable state while in their camps, mentally, physically, and economically. They miss their homes, jobs, and their old community. While waiting to hear about their asylum status, they want to have a sense of normality. Refugees have limited access to job opportunities, which delays productivity for families. When trying to strive for normality in their current state, having a steady source of income will stabilize their lives.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to …

Life, Kendall Hancock (Fashion Design), Damien Vela, Fancy Castillo, Monica Barrera (Interior Design), Terry Rim

Nexus Maximus

This project is about offering a solution to nationally displaced populations. Our group has created a system that will not only provide people with housing but a piece of mind.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope of finding safety and a better tomorrow. The …

Bookbox, Suraksha Chandrasekhar (Dmm), Anna Marinina (Computer Science), Gabrielle Schwartz (Mba, Marketing/Business Analytics), Erica Lomando (Interior Design), Sarah Von Lange (Health Sciences)

Nexus Maximus

Bookbox is an app that unites the world through books. With a motto of "Donate a book, start a new chapter" Bookbox aims to facilitate the flow of donated books to refugees in Syrian refugee camps, with a goal of promoting education, self-learning and the will to build a future.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. …

Mobile Health One Kiosk, Nathoue Noel (Public Administration), Giana Castelli (Interior Design), Nazanin Salehima (Interior Design), Queen Mgbechinyere (Nursing), Yasir Almukhifi (Disaster Management And Medicine), Salwa Rasheed (Textile Design)

Nexus Maximus

The goal of this machine is to decrease the wait time to see a physician or doctor when a refugee goes to a clinic. The machine will perform the first tests that a nurse would have to do before the patient meet the doctor. The machine allows this process to be quicker by doing tests, set up appointments for refugees to see a doctor,give the estimated wait time at clinics and also to direct people to the right section of the clinic once they get there.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the …

Respiratory Sinus Arrhythmia Activity Predicts Internalizing And Externalizing Behaviors In Non-Referred Boys, Wei Zhang, Shawn E. Fagan, Yu Gao

Publications and Research

Atypical respiratory sinus arrhythmia (RSA), a biomarker of emotion dysregulation, is associated with both externalizing and internalizing behaviors. In addition, social adversity and gender may moderate this association. In this study, we investigated if RSA (both resting RSA and RSA reactivity in an emotion regulation task) predicts externalizing and/or internalizing behaviors and the extent to which social adversity moderates this relationship. Two hundred and fifty-three children (at Time 1, mean age D 9.05, SD D 0.60, 48% boys) and their caregivers from the community participated in this study. Resting RSA and RSA reactivity were assessed, and caregivers reported children’s externalizing …

Half Full: A Personal Water Collection System, Matthew Cuccurese (Industrial Design), Andres Valbuena, Pooja Joshi (Occupational Therapy), Sophia Warne Rowe (Interior Design), Samantha Ringer (Interior Design)

Nexus Maximus

Our project focuses on the issue of water within refugee camps. We have proposed a system that can allow for individuals to be able to have their own source of drinking water with a device that can condensate water from the air, even in an aired region. This would allow them to use less water from the community's supply overall, and allow more water to be able to be rationed for uses like washing and cleaning than is currently rationed per person.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our …

Hsc Committee Meeting Minutes August 8 2017, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

A Word From The Writing Center (September 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Tip: Sentences that start with the word there
• Communication Skills Workshop Series: Communicate Like a Pro: Think like a...

A Validated Measure For Fertility Awareness: An Essential Step Toward Informed Reproductive Decision-Making, Brennan Peterson

Marriage and Family Therapy Faculty Articles and Research

"The efforts by Kudesia and colleagues (1) to create and validate a fertility awareness survey is a vital development in the field of reproductive health care. The 29-item Fertility and Infertility Treatment Knowledge Score (FIT-KS) was created to measure fertility awareness and infertility treatment knowledge in the general population and among medical trainees. Using a combination of existing questionnaires, consultation with specialists in test construction, and clinical recommendations of an expert panel of 15 reproductive endocrinologists, the FIT-KS is the first of its kind in the United States. The authors should be commended for their foresight and attempts to address …

Medical School Watercooler Newsletter - September 10, 2017, Lindsey Lyle

Watercooler Newsletter

This is the September 10, 2017 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

USA Health Staff Dancing For Patients’ Health

Mark Your Calendar: Mobile Medical Museum Lecture to Feature Dr. Paul Kelton

Dr. Jonathan Rayner Appointed Director of Laboratory of Infectious Diseases

USA Health Honors Employees at Jags Game

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As A Graft Source For T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide., Asad Bashey, Mei-Jie Zhang, Shannon R Mccurdy, Andrew St Martin, Trevor Argall, Claudio Anasetti, Stefan O Ciurea, Omotayo Fasan, Sameh Gaballa, Md, Mehdi Hamadani, Pashna Munshi, Monzr M Al Malki, Ryotaro Nakamura, Paul V O'Donnell, Miguel-Angel Perales, Kavita Raj, Rizwan Romee, Scott Rowley, Vanderson Rocha, Rachel B Salit, Melhem Solh, Robert J Soiffer, Ephraim Joseph Fuchs, Mary Eapen

Department of Medicine Faculty Papers

Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM). With increasing use of mobilized peripheral blood (PB), we compared transplant outcomes after PB and BM transplants. Patients and Methods A total of 681 patients with hematologic malignancy who underwent transplantation in the United States between 2009 and 2014 received BM (n = 481) or PB (n = 190) grafts. Cox regression models were built to examine differences in transplant outcomes by graft type, adjusting for patient, disease, and transplant characteristics. Results Hematopoietic recovery was similar after transplantation of BM and PB (28-day neutrophil …

Interventions To Attenuate The Psychological Effects Of Trauma On Front Staff Nurses: An Integrated Review Of Literature, Sarah Tisser

Grace Peterson Nursing Research Colloquium

No abstract provided.

Conditional Random Slope: A New Approach For Estimating Individual Child Growth Velocity In Epidemiological Research, Michael Leung, Diego G. Bassani, Amy Racine‐Poon, Anna Goldenberg, Syed Asad Ali, Gagandeep Kang, Prasanna S. Premkumar, Daniel E. Roth

Department of Paediatrics and Child Health

Objectives: Conditioning child growth measures on baseline accounts for regression to the mean (RTM). Here, we present the “conditional random slope” (CRS) model, based on a linear-mixed effects model that incorporates a baseline-time interaction term that can accommodate multiple data points for a child while also directly accounting for RTM.
Methods: In two birth cohorts, we applied five approaches to estimate child growth velocities from 0 to 12 months to assess the effect of increasing data density (number of measures per child) on the magnitude of RTM of unconditional estimates, and the correlation and concordance between the CRS and four …

Finding The Right Fit To Improve Colorectal Cancer Screening, Joseph Spataro, Richard Denicola, Drew Kotler, Md, Albert Lee, Md

Department of Medicine Posters

Background

• An estimated 28% of eligible US adults have never been screened for colorectal cancer (CRC) 2
• Fecal Immunochemical Testing (FIT) offers an acceptable non-invasive screening option
• An estimated 56% of patients at our internal medicine clinic have not had colorectal cancer screening and alternatives to colonoscopy were seldom promoted

Poster presented at: Pennsylvania Society of Gastroenterology (PSG) Annual Scientific Meeting 2017 at Nemacolin Woodlands Resort, Farmington, Pennsylvania, United States of America.

Intimate Partner Violence-Related Hospitalizations In Appalachia And The Non-Appalachian United States, Danielle M. Davidov, Stephen M. Davis, Motao Zhu, Tracie O. Afifi, Melissa Kimber, Abby L. Goldstein, Nicole Pitre, Kelly K. Gurka, Carol Stocks

Clinical and Translational Science Institute

The highly rural region of Appalachia faces considerable socioeconomic disadvantage and health disparities that are recognized risk factors for intimate partner violence (IPV). The objective of this study was to estimate the rate of IPV-related hospitalizations in Appalachia and the non-Appalachian United States for 2007–2011 and compare hospitalizations in each region by clinical and sociodemographic factors. Data on IPV-related hospitalizations were extracted from the State Inpatient Databases, which are part of the Healthcare Cost and Utilization Project. Hospitalization day, year, in-hospital mortality, length of stay, average and total hospital charges, sex, age, payer, urban-rural location, income, diagnoses and procedures were …

The Musicality Of The Water Lilies/La Musicalité Des Nymphéas (Library Resources), Holy Cross Libraries

Library Resources for Campus Events

A bibliography of resources available through the Holy Cross Libraries which provide additional information related to the Iris and B. Gerald Cantor Art Gallery exhibition “Gabrielle Thierry: The Musicality of the Water Lilies/La Musicalité des Nymphéas” from Aug. 30 through Oct. 7.

Thierry’s series of eight large-scale paintings were inspired by her rediscovery of the “Water Lilies” landscapes by Claude Monet on view at the the Musée de l’Orangerie in Paris. With special permission from the museum, Thierry painted in front of Monet’s originals over a period of 18 months from 2010 to 2012, where she explored the inner musical …

In Place: September 8, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• PLACE and What's the Big Idea?
• Spotlight On: The First Year Experience
• Our PLACE Theme in the News

Trkb-Enhancer Facilitates Functional Recovery After Traumatic Brain Injury, John Marshall, Joanna Szmydynger-Chodobska, Mengia S. Rioult-Pedotti, Kara Lau, Andrea T. Chin, Siva K. Reddy Kotla, Rakesh Tiwari, Keykavous Parang, Steven W. Threlkeld, Adam Chodobski

Pharmacy Faculty Articles and Research

Brain-derived neurotrophic factor (BDNF), a key player in regulating synaptic strength and learning, is dysregulated following traumatic brain injury (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional recovery. This study investigates whether CN2097, a peptidomimetic ligand which targets the synaptic scaffold protein, postsynaptic density protein 95, to enhance downstream signaling of tropomyosin-related kinase B, a receptor for BDNF, can improve neurological function after TBI. Moderate to severe TBI elicits neuroinflammation and c-Jun-N-terminal kinase (JNK) activation, which is associated with memory deficits. Here we demonstrate that CN2097 significantly reduces the post-traumatic synthesis of proinflammatory mediators and inhibits the …

Chloride Intracellular Channel Proteins Respond To Heat Stress In Caenorhabditis Elegans, Jun Liang, Yakov Shaulov, Cathy Savage-Dunn, Stéphane Boissinot, Tasmia Hoque

Publications and Research

Chloride intracellular channel proteins (CLICs) are multi-functional proteins that are expressed in various cell types and differ in their subcellular location. Two CLIC homologs, EXL-1 (excretory canal abnormal like-1) and EXC-4 (excretory canal abnormal± 4), are encoded in the Caenorhabditis elegans genome, providing an excellent model to study the functional diversification of CLIC proteins. EXC-4 functions in excretory canal formation during normal animal development. However, to date, the physiological function of EXL-1 remains largely unknown. In this study, we demonstrate that EXL-1 responds specifically to heat stress and translocates from the cytoplasm to the nucleus in intestinal cells and body …

A Global Staphylococcus Aureus Proteome Resource Applied To The In Vivo Characterization Of Host-Pathogen Interactions., Stephan Michalik, Maren Depke, Annette Murr, Manuela Gesell Salazar, Ulrike Kusebauch, Zhi Sun, Tanja C Meyer, Kristin Surmann, Henrike Pförtner, Petra Hildebrandt, Stefan Weiss, Laura Marcela Palma Medina, Melanie Gutjahr, Elke Hammer, Dörte Becher, Thomas Pribyl, Sven Hammerschmidt, Eric W Deutsch, Samuel L Bader, Michael Hecker, Robert L Moritz, Ulrike Mäder, Uwe Völker, Frank Schmidt

Articles, Abstracts, and Reports

Data-independent acquisition mass spectrometry promises higher performance in terms of quantification and reproducibility compared to data-dependent acquisition mass spectrometry methods. To enable high-accuracy quantification of Staphylococcus aureus proteins, we have developed a global ion library for data-independent acquisition approaches employing high-resolution time of flight or Orbitrap instruments for this human pathogen. We applied this ion library resource to investigate the time-resolved adaptation of S. aureus to the intracellular niche in human bronchial epithelial cells and in a murine pneumonia model. In epithelial cells, abundance changes for more than 400 S. aureus proteins were quantified, revealing, e.g., the precise temporal regulation …

Acute And Late Toxicities Of Concurrent Chemoradiotherapy For Locally-Advanced Non-Small Cell Lung Cancer., Vivek Verma, Charles B 2nd Simone, Maria Werner-Wasik

Department of Radiation Oncology Faculty Papers

For patients with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC), concurrent chemoradiotherapy improves overall survival as compared to sequential chemotherapy and radiation therapy, but is associated with higher rates of toxicities. Acute, clinically significant esophagitis or pneumonitis can occur in one in five patients. The risks of esophagitis and pneumonitis can impact the decision to deliver concurrent therapy and limit the total dose of radiation therapy that is delivered. Hematologic toxicities and emesis are common toxicities from systemic therapies for LA-NSCLC and can result in delaying chemotherapy dosing or chemotherapy dose reductions. Late treatment morbidities, including pulmonary fibrosis and cardiac …

Quality Assessment Of The Efficacy And Cost-Effectiveness Of Fecal Microbiota Transplant For Recurrent Clostridium Dfficile Infection., Eric Nellis Md, Shashin Shah Md

Department of Medicine

No abstract provided.

Evaluation Of Xpert Mtb/Rif Testing For Rapid Diagnosis Of Childhood Pulmonary Tuberculosis In Children By Xpert Mtb/Rif Testing Of Stool Samples In A Low Resource Setting, Zahra Hasan, Sadia Shakoor, Fehmina Arif, Aisha Mehnaz, Alnoor Akber, Marium Haider, Akber Kanji, Rumina Hasan

Department of Pathology and Laboratory Medicine

Objective: Children with tuberculosis (TB) remain underdiagnosed due to difculty in testing for Mycobacterium tuberculosis (MTB) infection. We evaluated the Xpert MTB/RIF assay for respiratory and stool testing in children for pulmonary TB through a cross-sectional study at tertiary care facilities in Karachi, Pakistan. Fifty children aged 0–15 years screened by a modifed Kenneth-Jones (KJ) score were included. Mycobacterial culture of respiratory samples was the microbiological standard against stool Xpert TB results. All positive TB cases were compared against a treatment response standard (TRS).
/="/">Results: Twelve study subjects were diagnosed by Xpert TB and nine by MTB culture. Compared …

The Strong Cell-Based Hydrogen Peroxide Generation Triggered By Cold Atmospheric Plasma., Dayun Yan, Haitao Cui, Wei Zhu, Annie Talbot, Lijie Grace Zhang, Jonathan H Sherman, Michael Keidar

Surgery Faculty Publications

Hydrogen peroxide (H2O2) is an important signaling molecule in cancer cells. However, the significant secretion of H2O2 by cancer cells have been rarely observed. Cold atmospheric plasma (CAP) is a near room temperature ionized gas composed of neutral particles, charged particles, reactive species, and electrons. Here, we first demonstrated that breast cancer cells and pancreatic adenocarcinoma cells generated micromolar level H2O2 during just 1 min of direct CAP treatment on these cells. The cell-based H2O2 generation is affected by the medium volume, the cell confluence, as well as the discharge voltage. The application of cold atmospheric plasma (CAP) in cancer …

Researchers Call For End Of Ied Use In Warfare, Adela Talbot

Data and Test Instruments

At one point in history, a soldier in combat would have been injured with a bow and arrow. That bow and arrow eventually became a bullet, and in the 1890s, that bullet evolved into the ‘dum-dum bullet,’ designed to expand on impact and inflict severe injury. Because of its potential to gravely wound combatants, The Hague Convention of 1899 prohibited the use of the dum-dum bullet in international warfare.A century later, landmines, designed to maim and injure, rather than kill, were deemed indiscriminate weapons with potential to inflict serious injury. After a high-profile campaign waged by a coalition of non-governmental …

Silver Oxide Coatings With High Silver-Ion Elution Rates And Characterization Of Bactericidal Activity., Sarah S Goderecci, Eric Kaiser, Michael Yanakas, Zachary Norris, Jeffrey Scaturro, Robert Oszust, Clarence D Medina, Fallon Waechter, Min Heon, Robert R Krchnavek, Lei Yu, Samuel E Lofland, Renee M Demarest, Gregory A Caputo, Jeffrey D Hettinger

Rowan-Virtua School of Osteopathic Medicine Departmental Research

This paper reports the synthesis and characterization of silver oxide films for use as bactericidal coatings. Synthesis parameters, dissolution/elution rate, and bactericidal efficacy are reported. Synthesis conditions were developed to create AgO, Ag₂O, or mixtures of AgO and Ag₂O on surfaces by reactive magnetron sputtering. The coatings demonstrate strong adhesion to many substrate materials and impede the growth of all bacterial strains tested. The coatings are effective in killing Escherichia coli and Staphylococcus aureus, demonstrating a clear zone-of-inhibition against bacteria growing on solid media and the ability to rapidly inhibit bacterial growth in planktonic culture. Additionally, the coatings exhibit very …

Linking Spinal Cord Injury Rehabilitation Between The World Wars: The R. Tait Mckenzie Legacy., John F. Ditunno, Jr

Department of Rehabilitation Medicine Faculty Papers

Spinal cord injury (SCI) medicine emerged after World War II due to mass casualties, which required specialized treatment centers. This approach to categorical care, however, was first developed during World War I, led by pioneers R. Tait McKenzie and George Deaver, who demonstrated that soldiers disabled by paralysis could return to society through fitness/mobility, recreational and vocational training. McKenzie, a Canadian and the first professor of physical therapy in the US, influenced Deaver and military physicians in Britain, Canada, and the U.S. with his achievements and publications. Although early mortality from SCI was high, advances in the treatment of skin …

Culture Of Mobility, Beth Colborn, Dpt, Helene Daly, Msn, Rn, Kathleen Hilbert, Rn, Msn, Cm, Gordon R. Reeves, Md, Jessica Shank, Pt, Mpt, Elizabeth Singh, Dpt, Lisa Wus, Dnp, Rn, Crnp, Pccn-Cmc

Department of Rehabilitation Medicine Posters

Objectives

•Create an interdisciplinary approach to patient mobility and functional independence

•Provide education and support to lead a culture of mobility

•Develop a system that reduces immobility related adverse outcomes and promotes overall patient well-being

•Utilize evidence based practice to create a program that will decrease variation in patient care in order to optimize hospital based outcomes