Medicine and Health Sciences Commons^™

Evaluating The Impact Of A Smoking Cessation Program., Gideon Eke

Walden Dissertations and Doctoral Studies

Forty-six million individuals in the United States used tobacco products. People who use

tobacco products attempt numerous strategies before giving up smoking habit altogether. The goal of this project was to evaluate the impact of a tobacco cessation program by evaluating pre-and post-cessation program data, and hospital records of participants attending the hospital smoking cessation program over a 6-month period to ascertain the degree of reduction in tobacco use and hospitalization from smoking-related diseases. The population sample comprised of both men and women between the ages of 18 years and above. The project question addressed whether the smoking cessation program …

How Heroin-Addicted Offenders Experience Sobriety Upon Release From Jail, Rebecca Lynn Foster

Walden Dissertations and Doctoral Studies

Heroin addiction is a growing epidemic in the United States. The need for proper treatment programs accessible by heroin users who wish to or are mandated to participate in recovery programs is a growing need, and pathways to sobriety for ex-offenders have presented in literature as understudied. The purpose of this study was to examine heroin-addicted offenders' experiences prior to and after release on their paths to sobriety. This study followed a qualitative phenomenological approach based on the theory of personal causation, which posits that individuals see events in life as either driven by themselves or caused by others, both …

Use Of Tai Chi To Treat Mental Health Disorders In Veterans, Mekeesha Mcclure

Walden Dissertations and Doctoral Studies

Clinicians have a challenge of discovering and implementing new ways to address their patients' health concerns. Some healthcare needs are not completely managed with pharmacotherapy and invasive procedures alone. Military veterans compose a special group due to multiple needs related to physical and emotional symptoms resulting from exposure to trauma. This project explored the benefits of a Tai Chi recreational therapy program. The goal of this trial was to examine gentle movement routines of Tai Chi for emotional benefits for veterans. The literature review provided insight from current evidence into the probable outcome of including alternative medicine options into regular …

Effectiveness Of Gaming In Creating Cultural Awareness, Chenit Ong-Flaherty, D. Valencia-Garcia, D. A. Martinez, W. Borges, L. Summers

Nursing and Health Professions Faculty Research and Publications

Despite the emphasis on cultural competency education in the United States for the past three decades, inequities and disparities in healthcare continue to persist, particularly among minority populations. With the current growing gap in provider and patient cultural congruence, how effectively we train students to work with diverse populations in healthcare settings warrants attention. This article presents the results of a qualitative study on the effectiveness of experiential learning, in the form of the game BaFa’ BaFa,’ in raising cultural awareness among students of health professions. Using thematic analysis, the authors analyzed written reflections from student participants. The findings support …

How Useful Is Electroencephalography In The Diagnosis Of Autism Spectrum Disorders And The Delineation Of Subtypes: A Systematic Review, Oana Gurau, William Bosl, Charles R. Newton

Nursing and Health Professions Faculty Research and Publications

Autism spectrum disorders (ASD) are thought to be associated with abnormal neural connectivity. Presently, neural connectivity is a theoretical construct that cannot be easily measured. Research in network science and time series analysis suggests that neural network structure, a marker of neural activity, can be measured with electroencephalography (EEG). EEG can be quantified by different methods of analysis to potentially detect brain abnormalities. The aim of this review is to examine evidence for the utility of three methods of EEG signal analysis in the ASD diagnosis and subtype delineation. We conducted a review of literature in which 40 studies were …

Shinrin-Yoku (Forest Bathing) And Nature Therapy: A State-Of-The-Art Review, Margaret M. Hansen Edd, Msn, Rn, Reo Jones, Kirsten Tocchini

Nursing and Health Professions Faculty Research and Publications

Background: Current literature supports the comprehensive health benefits of exposure to nature and green environments on human systems. The aim of this state-of-the-art review is to elucidate empirical research conducted on the physiological and psychological effects of Shinrin-Yoku (or Forest Bathing) in transcontinental Japan and China. Furthermore, we aim to encourage healthcare professionals to conduct longitudinal research in Western cultures regarding the clinically therapeutic effects of Shinrin-Yoku and, for healthcare providers/students to consider practicing Shinrin-Yoku to decrease undue stress and potential burnout. Methods: A thorough review was conducted to identify research published with an initial open date range …

Tablet App For Child Cognitive Assessment In Low And Middle Income Countries, Patricia A. Francis-Lyon, Yasser Attiga, Rashmi Manjunath, Uma Ramasubramanian, Vaishali Chaudhuri, Tri Nguyen, Xiangyi Xu

Nursing and Health Professions Faculty Research and Publications

No abstract provided.

Mammary Extracellular Matrix Directs Differentiation Of Testicular And Embryonic Stem Cells To Form Functional Mammary Glands In Vivo, Robert D. Bruno, Jodie M. Fleming, Andrea L. George, Corinne A. Boulanger, Pepper Schedin, Gilbert H. Smith

School of Medical Diagnostics & Translational Sciences Publications

Previously, we demonstrated the ability of the normal mammary microenvironment (niche) to direct non-mammary cells including testicular and embryonic stem cells (ESCs) to adopt a mammary epithelial cell (MEC) fate. These studies relied upon the interaction of transplanted normal MECs with non-mammary cells within the mammary fat-pads of recipient mice that had their endogenous epithelium removed. Here, we tested whether acellular mammary extracellular matrix (mECM) preparations are sufficient to direct differentiation of testicular-derived cells and ESCs to form functional mammary epithelial trees in vivo. We found that mECMs isolated from adult mice and rats were sufficient to redirect testicular derived …

Message, N Udupa Dr

Manipal Journal of Nursing and Health Sciences

No abstract provided.

Message, Anice George Dr

Manipal Journal of Nursing and Health Sciences

No abstract provided.

Invited Article, Joseph Thomas Dr

Manipal Journal of Nursing and Health Sciences

No abstract provided.

Effect Of Family Intervention On Functioning Among Patients With Chronic Schizophrenia, Sreeja I Ms

Manipal Journal of Nursing and Health Sciences

Introduction: Schizophrenia is a chronic major psychotic disorder, manifested by distorted thinking and poor emotional response. Patients diagnosed with schizophrenia have inability in performing basic individual and social roles or activities. Improving personal, occupational, and social aspects of functioning is an important treatment aim for such patients. Objective: 1. To assess the effect of family intervention on patient functioning, and 2. To find out association of patient functioning with demographic variables. Methods: A quasi-experimental nonequivalent control group design and consecutive sampling was adopted for the study. The population under study was patients having chronic schizophrenia and their caregivers in Thiruvananthapuram …

Adjustment, Perceived Safety And Mental Wellbeing Among Professional College Students, Blessy Prabha Valsaraj Dr, Savitha, Shalini Devendra Nayak Ms

Manipal Journal of Nursing and Health Sciences

Introduction: Adjustment is an essential element for each individual to lead life well. It is the way in which a person adapts with his or her environment. The college atmosphere plays an important role in developing psychosocial wellbeing and helping in promoting mental health of the students. Objectives: The study is aimed at assessing correlation on adjustment, perceived safety, and mental wellbeing among professional college students. Materials and Methods: The study was conducted in different professional colleges of Manipal University, using descriptive correlative study design. Cluster sampling was adopted for selecting the professional colleges and the further batches. Thus, 339 …

A Comparative Study To Assess The Level Of Pain During Nursing Procedures In Ventilated, Unconscious And/Or Sedated Patients, Betbhalin Mukhim Ms, Manashi Sengupta Ms, Rikupar Iawin

Manipal Journal of Nursing and Health Sciences

Introduction: Pain is developed, when there is certain illness or injury. Patients under mechanical ventilator commonly experience pain, which is often overlooked. Factors such as stage of illness, invasive-procedures, and surgical interventions often aggravate pain in critical patients. Objective: The objective of this study was to assess pain levels among mechanically ventilated patients during routine nursing procedures by using the behavioral pain scale (BPS). Method: Non-experimental study was conducted among 30 mechanically ventilated patients admitted in ICU (Intensive Care Unit), in Down Town hospital Guwahati, Assam during different nursing interventions, fifteen patients were assessed during turning and fifteen patients were …

Knowledge And Attitude On Child Abuse Among School Teachers, In Selected Urban English Medium Schools Of Udupi District, Banbetlin Hynniewta Ms, Tessy Treesa Jose Dr, Anjali K. G Ms

Manipal Journal of Nursing and Health Sciences

Introduction: Child abuse continues to be one of the primary threats to the child’s emotional and social well-being globally. As students spend maximum time in school, teachers need to be trained to recognize physical and behavioural changes associated with abuse in order to confidently determine the cause and plan interventions appropriately. The inadequate knowledge and information lead to gap in the crucial role of teachers in identification and early assistance of an abused child. Objectives: The objectives of the study were to assess the knowledge of the school teachers on child abuse, to determine the attitude of school teachers on …

Palliative Sedation In An Adolescent With Intractable Respiratory Distress: Ethical Issues And Doctrine Of Double Effect, Malathi G. Nayak Ms, Anice George Dr, Naveen Salins Dr

Manipal Journal of Nursing and Health Sciences

Introduction Intractable respiratory distress is the second most common indication for palliative sedation in a palliative care setting; the most common indication is uncontrolled and unrelieved refractory pain. This case is presented to highlight the complexities of managing respiratory distress in a terminal phase of illness and its associated ethical issues

Nasal Pseudotumour In A Haemophilic: A Case Report, Sulochana B Ms, Balakrishna, Kailesh Pujary, Annamma Kurien Dr

Manipal Journal of Nursing and Health Sciences

Haemophilia is an X linked inherited coagulation disorder. A haemophilic pseudotumour is one of the rarer complications of haemophilia, which results from repetitive bleeding. These have become scarcer over the years with better treatment facilities for bleeding disorders like factor replacement (Pakala, Thomas, & Philip, 2012). The present case report details the history and clinical course of a 23–year-old case with recurrent nasal bleed and nasal pseudotumour, which showed a positive outcome after surgical intervention and factor replacement. At 3-month follow-up, the patient was evaluated by endoscopy, CT scan, and there was no evidence of recurrence

Management Of Simultaneous Bilateral Femur Fractures In A Tertiary Care Hospital: A Retrospective Review, Masood Umer, Syed Zohaib Gulzar Naqvi, Raza Askari, Umair Ashraf

Department of Surgery Docs

Abstract: Introduction: Bilateral long bone fractures are rare and usually are associated with increased risk of complications. These fractures are usually associated with poly traumatic injuries or high impact trauma resulting in shock. Commonest etiology is road traffic accident. Closed diaphyseal fractures are best managed by intramedullary nailing; management becomes difficult if there are open fractures and late arrival. In this study we intend to present our experience of managing these patients. Materials and Methods: Medical records of all adult patients (age more than 16 years of age) admitted at Aga Khan University and Hospital with bilateral femur fractures +/- …

Hernia Of Morgagni Presenting As Constipation In A 65-Year-Old Male, Hamza A Khan, Adeel Samad, Omar A Khan, Farida K Chagan, Jamal K Khan, Saulat H. Fatimi

Department of Surgery Docs

Hernia of Morgagni is congenital defects in the diaphragm. They are mostly asymptomatic and present with vague symptoms when they do so. A high index of suspicion is required for timely diagnose of this condition. Here we present the case of a 65-year-old male patient presented to our institute with constipation for the past six months. Chest radiology raised the suspicion of a hernia which was further confirmed by contrast studies. Laparotomy was done and the hernia sac identified, colon and greater omentum reduced and defect repaired. He was discharged in stable condition and was doing well on follow-up.

Preclinical Evaluation Of Ag10 For Therapeutic Use Against Familial Amyloid Cardiomyopathy And Its Application In Various Other Technologies, Mark Russell Miller

University of the Pacific Theses and Dissertations

Transthyretin (TTR) amyloidosis is a progressive, fatal disease in which deposition of amyloid derived from either mutant or wild-type TTR causes severe organ damage and dysfunction. TTR cardiomyopathy is an infiltrative, restrictive cardiomyopathy characterized by progressive left and right heart failure. Familial amyloid cardiomyopathy (FAC) is driven by pathogenic point mutations in the TTR gene that destabilize the TTR tetramer, prompting its dissociation into dimers and monomers, with subsequent misfolding, aggregation and deposition of toxic TTR amyloid aggregates in the myocardium. The most prevalent mutation that causes FAC is the V122I variant, carried by 3.4% of African Americans, that increases …

The Role Of Rig-I And Mda5 In Alphavirus Replication, Ivan Viachaslavavich Akhrymuk

All ETDs from UAB

Evolution of vertebrates has resulted in the development of a wide range of cellular pattern recognition receptors (PRRs), which detect the presence of virus-specific molecules termed pathogen-associated molecular patterns (PAMPs). Sensing of the incoming viruses and/or their replication by PRRs activates the cascade of cellular pathways that ultimately result in activation of antiviral response. Such response is determined by hundreds of cellular genes, whose products either directly interfere with virus replication or are released from the cells and activate antiviral state in yet uninfected cells. Consequently, the latter cell signaling prevents development of the next rounds of infection both in …

African American Child And Adolescent Obesity: The Parents Perspective, Alice Marie Austin

All ETDs from UAB

Nearly 36% of African American children ages 2 to 19 are overweight or obese. Childhood obesity results in children with social and psychological disorders, chronic disease, and an increase in morbidity and mortality. Solutions have been offered but none have made a significant impact on African American children living in the Southern United States. Studies that implement life style change produce short-term reductions in African American children but few show life-long change. Parents are responsible for making lifestyle choices for children, it is imperative to understand parental perceptions of child and adolescent obesity and its relationship to lifestyle change. The …

An Exploration Of The Underlying Mechanisms Causing Spasticity In Young People With Cerebral Palsy, Alexis Carnes

College of Graduate Studies: Theses & Dissertations

Background and Objective(s): Spasticity is a common symptom experienced by individuals with cerebral palsy (CP). Spastic CP is often accompanied by hypertonia. Currently, there is a limited understanding of the contributions of spasticity to hypertonia which can in turn hinder the development of new rehabilitative measure to improve these conditions. Additionally, clinical evaluation of spasticity is limited to observational techniques such as the Ashworth scale. The purpose of this study was to compare differences in passive joint torque in the upper extremity between individuals with severe, spastic CP (MACS III-V) and healthy, age-matched controls at different speeds during passive stretching. …

Variability And Stability Of 13 To 19 Month Olds Infants' Gait Affect By Wet And Dry Diaper And Underwear, Sally Marie Futch

College of Graduate Studies: Theses & Dissertations

Research has been conducted on the effect of diaper perturbation versus unclothed on gait, but there is little research on different diaper perturbations on gait. PURPOSE: The purpose of this study was to examine how physical perturbations (dry and wet diaper and underwear) affected 13 to 19 month old infant’s gait. METHODS: Sixty infants (13-19 month old) were recruited for the study. Five trials for 3 conditions (dry and wet diaper and underwear) were conducted on a GaitRite walkway. Step length (m/step), cadence (steps/s), support base (m) and stance time (sec) were analyzed. A mixed model with repeated measures along …

The Effect Of Acute Pain On Executive Function, Jenna M. Morogiello

College of Graduate Studies: Theses & Dissertations

Background: Executive functions are high-level cognitive processes that allow a person to successfully engage in an independent and self-fulfilling life. Previous literature indicates that acute pain can affect executive function, which may be due to a limited amount of shared neural resources of the brain.

Objective: The purpose of this study was to determine if acute pain affects executive function in recreationally active individuals who sustain a musculoskeletal injury.

Methodology: Twenty-four participants who presented with acute pain due to a musculoskeletal injury underwent a neuropsychological battery within 72 hours of injury and within two weeks from the initial testing session. …

Concussion Knowledge And Understanding In Ghsa Guardians, Chloe C. Salway

College of Graduate Studies: Theses & Dissertations

Context: Concussions are a serious injury that could result in both short and long-term consequences, particularly if not recognized and managed appropriately. Concussion education has been implemented, mostly as a result of Concussion legislation. Coach and athlete concussion education has been evaluated in the literature, however the literature is scarce on parental concussion education.

Purpose: To assess concussion knowledge and understanding in guardians of Georgia High School Association (GHSA) student-athletes that completed the GHSA concussion awareness form, in comparison to those that received additional concussion education.

Methods: This study utilized a prospective cross-sectional descriptive research design. Participants were GHSA guardians …

Dihydropyridines As Calcium Channel Blockers: An Overview, Thelma Salazar, Andres Gonzalez, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Cardiovascular disease remains one of the leading causes of death in the United States. It is estimated that 1 in every 3 American adults suffer from high blood pressure. Hypertension, a precursor to most cardiovascular diseases, continues to grow at an alarming rate and is seldom managed carefully. Attempts have been made to manage hypertension and reduce the morbidity and mortality of the cardiovascular organ through methods including diets, increased amount of exercise, and medications. Many commercial drugs have been derived from dihydropyridine due to its antihypertensive property. Dihydropyridine derivatives work by acting as calcium channel blockers blocking the intake …

Differences In Trunk And Hip Flexion/Extension Strength, Jasmin Brown

College of Graduate Studies: Theses & Dissertations

Context: The definition of the “core” within the literature is misconstrued: some researchers believe the core only involves muscles of the trunk while others believe it also includes muscles of the hip. Core strength tests typically include exercises that activate hip flexors and extensors without a firm definition of the “core” including the muscles of the hip. Purpose: The purpose of this study was to differentiate between the strength of the trunk and hip during flexion and extension.

Methods: Participants included 28 Division I collegiate athletes from a single university (12 males, 16 females, height (in.) = 69.14 ± 4.81, …

Development Of A Health Care Systems Curriculum., Zachary Pruitt, Rahul Mhaskar, Bryan G. Kane Md, Robert D. Barraco Md, Mph, Deborah J Dewaay, Alexander M. Rosenau Do, Kristin A. Bresnan Md, Marna R. Greenberg Do, Mph, Facep

Department of Emergency Medicine

Background: There is currently no gold standard for delivery of systems-based practice in medical education, and it is challenging to incorporate into medical education. Health systems competence requires physicians to understand patient care within the broader health care system and is vital to improving the quality of care clinicians provide. We describe a health systems curriculum that utilizes problem-based learning across 4 years of systems-based practice medical education at a single institution.

Methods: This case study describes the application of a problem-based learning approach to system-based practice medical education. A series of behavioral statements, called entrustable professional activities, was created …

Individual And Institutional Level Factors That Influence Hiv Testing And Counseling Utilization During Antenatal Care In Nigeria, Modupeoluwa O. Durojaiye

All ETDs from UAB

Of the estimated 150,000 new HIV infections in children in 2015, 122,000 occurred in sub-Saharan Africa (SSA), with Nigeria accounting for a third of all cases. Most of these infections were acquired via mother-to-child transmission (MTCT). HIV testing and counseling, a critical first step in the prevention of MTCT (PMTCT), can ensure that HIV-positive women access services that can reduce HIV transmission risk. Incorporating HIV testing and counseling into antenatal care (ANC) is an integral component of the World Health Organization (WHO) strategies. This dissertation aims to understand factors that influence HIV testing and counseling during ANC. It is comprised …