Medicine and Health Sciences Commons^™

Effectiveness Of The Graston Technique For Soft Tissue Injuries Such As Bicipital Tendinopathy: A Case Report, Brian Storhaug

Physical Therapy Scholarly Projects

Abstract: This case report discusses a unique approach to the treatment of a soft tissue injury, such as bicipital tendonitis, through the approach called the Graston Technique.

Case Description: A 61 year old Caucasian male received treatment after a diagnosis of bicipital tendonitis. His job was working at a mail office which required repetitive manual labor consisting of moving boxes of varying weight and height in a position of protracted shoulders, extended elbows and supinated wrists. Treatment consisted of stretching the biceps brachii and upper trapezius, Graston, cross friction massage, ultrasound and therapeutic exercise.

Background and purpose: …

Maximizing Functional Outcomes In A Patient With A Complete Cervical Spinal Cord Injury, Samantha Braegelmann

Physical Therapy Scholarly Projects

Background and Purpose: Spinal cord injury is damage sustained to any nervous tissue in the spinal cord that results in loss or decreased motor function or sensation. Every year in the United States there is about 12,000 new cases of spinal cord injuries with young Caucasian males' most prevalent. The purpose of this scholarly article is to analyze various factors to maximize functional outcomes and determine the proper course of treatment following a spinal cord injury.

Case Description: Patient was a right handed Caucasian female who was involved in a minor motor vehicle accident and sustained a C7-Tl …

Electromyographic Analysis Of Sit To Stand Dependent Transfers With And Without Education On Lifting Technique, Jordan Braun, Samantha Stegman, Alex Wohl

Physical Therapy Scholarly Projects

PURPOSE: The purpose of this study was to assess if there was a change in electromyography (EMG) activity in the back or leg muscles when performing a dependent sit-to-stand lift before and after a brief proper lifting intervention.

SUBJECT: The subjects in this study included 10 female third-year doctoral physical therapy students from the University of North Dakota that were all in good health with no significant pathology of either their backs or lower extremities.

INSTRUMENTATION: The EMG activity was recorded by the Noraxon ™ TeleMyo 2400R G2 transmitter and a TeleMyo 2400 SG150 unit. Knee flexion …

Orthotic Satisfaction Survey, Jamie Bowman, Sarah Erickson

Physical Therapy Scholarly Projects

The foot is made up of many bones, joints, and ligaments that help support the foot and body. When these structures are not properly aligned the appropriate biomechanics of the foot become compromised. Foot orthotics act as a conservative method of treatment to address some of the painful symptoms associated with these conditions. Common problems that have previously been addressed include plantar fasciitis, stress fractures, shin splints, flat feet, hallux valgus, and patellofemoral, heel and back pain.

In this study, we hope to indicate when and where orthotic use is indicated and what diagnoses benefit most when using orthotics as …

Patellofemoral Pain Syndrome: A Case Report, Angela Kumm

Physical Therapy Scholarly Projects

Background and purpose. Patellofemoral pain syndrome (PFPS) is a common injury among young female athletes. It is difficult to determine the primary factor that contributes to its development due to the fact that there are multiple causes. Factors influencing the development of PFPS are increased quadriceps (Q) angle, patella alta, abnormal or excessive foot pronation, quadriceps muscle weakness, diminished flexibility of the hamstrings and rectus femoris muscles, malalignment of the femur, weakness of the hips, static and dynamic skeletal malalignment, and altered neuromuscular recruitment strategies.

Case Description. The patient was a young female collegiate track and cross country …

Patellofemoral Pain Syndrome: A Case Study, Alexandra Jares

Physical Therapy Scholarly Projects

Background and Purpose: Patellofemoral Pain Syndrome (PFPS) is one of the most common lower extremity disorders reported, with a higher prevalence among females and in active individuals. While quadriceps strengthening has generally been the chosen treatment approach, some studies have pointed to the importance and influence of the hip musculature. Patients with PFPS commonly present with decreased posterolateral strength, specifically in the hip abductors, hip extensors, and hip external rotators.

Case Description: The patient was a 13-year-old thin-framed female who was referred to physical therapy after dislocating her right patella during a twisting motion in dance class.

Interventions …

Pilot Study To Investigate The Influence Of The Timing Of Student Clinical Experiences And Student Characteristics In The Hiring Of New Graduates, Kjersten Skjold, Allison Vosgerau

Physical Therapy Scholarly Projects

Background and Purpose: Clinical experiences provide the student with the opportunity to practice technical skills as well as soft skills. This opportunity may benefit the student in future employment at the clinical facility. As the clinical experiences are at various time periods throughout the coursework, many students feel that the later sessions of clinical experiences may be more beneficial in employment opportunities upon graduation. Students also feel that grade point average plays an important role in potential employment opportunities.

Methods: A survey was developed to identify the influence clinical experience session times and student characteristics that support future employment …

An Interdisciplinary Analysis Of Core Competencies In Pain Management For Prelicensure Education: Curriculum Application For Physical And Music Therapy, Schaun Seaburg

Physical Therapy Scholarly Projects

Core competencies in pain management were recently established for prelicensure health professional education and assessed for ways that they could be integrated into professional physical therapy practice. The competencies present the expected minimal capabilities for graduating health care students for the subject of pain management. The pain competencies include 4 domains: multidimensional nature of pain, pain assessment and measurement, management of pain, and context of pain. The proposed competencies are recommended for educational programs and could be implemented for other health professions. The purpose of this study is to assess the implementation of the pain competencies in physical therapy and …

The Use Of Physical Therapy Evaluation And Treatment To Manage A Patient Following A Total Knee Arthroplasty: A Case Study, Scott Holm

Physical Therapy Scholarly Projects

Background and Purpose: The knee is a significant structure within the musculoskeletal system, which is used for dynamic and static movement in the environment. Obesity has been found to have significant health implications within all of the body's systems. The purpose of this case study is to evaluate the functional outcomes of an obese patient following a total knee arthroplasty and gain understanding of the impact that obesity has on functional improvement during postoperative physical therapy care of a total knee replacement.

Case Description: The patient is a 43 year old female, who has undergone a total knee …

Discrimination Of Mild Cognitive Impairment And Alzheimer's Disease Using Transfer Entropy Measures Of Scalp Eeg, Joseph Mcbride, Xiaopeng Zhao, Nancy Munro, Gregory Jicha, Charles Smith, Yang Jiang

Sanders-Brown Center on Aging Faculty Publications

Mild cognitive impairment (MCI) is a neurological condition related to early stages of dementia including Alzheimer's disease (AD). This study investigates the potential of measures of transfer entropy in scalp EEG for effectively discriminating between normal aging, MCI, and AD participants. Resting EEG records from 48 age-matched participants (mean age 75.7 years)-15 normal controls, 16 MCI, and 17 early AD-are examined. The mean temporal delays corresponding to peaks in inter-regional transfer entropy are computed and used as features to discriminate between the three groups of participants. Three-way classification schemes based on binary support vector machine models demonstrate overall discrimination accuracies …

Surface Functionalized Magnetic Nanoparticles For Cancer Therapy Applications, Robert J. Wydra

Theses and Dissertations--Chemical and Materials Engineering

Despite recent advances, cancer remains the second leading cause of deaths in the United States. Magnetic nanoparticles have found various applications in cancer research as drug delivery platforms, enhanced contrast agents for improved diagnostic imaging, and the delivery of thermal energy as standalone therapy. Iron oxide nanoparticles absorb the energy from an alternating magnetic field and convert it into heat through Brownian and Neel relaxations. To better utilize magnetic nanoparticles for cancer therapy, surface functionalization is essential for such factors as decreasing cytotoxicity of healthy tissue, extending circulation time, specific targeting of cancer cells, and manage the controlled delivery of …

Academic And Non-Academic Variables As Predictors Of Nclex-Rn Success Among Traditional Associate Degree Students At Southern Adventist University, Christine Moniyung

Dissertations

Problem

The School of Nursing at Southern Adventist University offers both Associate of Science and Bachelor of Science in nursing degrees. A majority of the students who sit for the NCLEX-RN are associate of science in nursing graduates. The pass rate dropped from 94.9% in 2010 to 88.8% in 2011. The pass rate went up to 93.3% in 2012, but dropped again by almost 5% in the following year, and to an all-time low of 76.5% in 2014.

Unlike most AS nursing program student populations in the nation, the majority of SAU students are young and considered traditional-age college students. …

A Faith-Based Primary Diabetes Prevention Intervention For At-Risk Puerto Rican Adults: A Feasibility Study, Sylvia Torres-Thomas

Electronic Theses and Dissertations

Diabetes is a serious health threat that disproportionately affects Hispanics of Puerto Rican heritage. Current evidence supports diabetes prevention programs to change health behaviors in people who are at risk and thus prevent the development of type 2 diabetes. However, few interventions exist for Hispanics, and even fewer have been designed for Puerto Rican adults. A literature review of community-based diabetes prevention programs involving at-risk Hispanics was conducted using a cultural sensitivity framework to determine the state of the science and identify gaps in knowledge regarding diabetes prevention for Puerto Ricans. An integrated theoretical framework was developed using constructs from …

Proof-Of-Concept Of Environmental Dna Tools For Atlantic Sturgeon Management, Jameson Hinkle

Theses and Dissertations

Abstract

The Atlantic Sturgeon (Acipenser oxyrinchus oxyrinchus, Mitchell) is an anadromous species that spawns in tidal freshwater rivers from Canada to Florida. Overfishing, river sedimentation and alteration of the river bottom have decreased Atlantic Sturgeon populations, and NOAA lists the species as endangered. Ecologists sometimes find it difficult to locate individuals of a species that is rare, endangered or invasive. The need for methods less invasive that can create more resolution of cryptic species presence is necessary. Environmental DNA (eDNA) is a non-invasive means of detecting rare, endangered, or invasive species by isolating nuclear or mitochondrial DNA (mtDNA) from the …

Eccentric Loading Increases Peak Torque Angle Of The Ankle Plantar Flexors In Healthy Volunteers, Matthew Willisch, Peter Hamer, Luke Hopper, Max Bulsara, James R. Debenham

Physiotherapy Papers and Journal Articles

Eccentric loading of the ankle plantar Flexor’s (PF) has demonstrated clinical efficacy in the conservative treatment of Achilles tendinopathy, however, its mechanism of therapeutic benefit remains unclear. The purpose of this study was to examine the effects of PF eccentric loading on PF angle to peak torque (AtPT), peak torque (PT) and lower limb vertical stiffness. Thirty healthy volunteers were randomised to an eccentric (n=15) or concentric (n=13) exercise group. A 10-week loading programme of the ankle plantar flexors was completed. AtPT, PT and vertical stiffness were compared within and between groups before and after the interventions. AtPT increased in …

Top 10 Research Questions To Promote Physical Activity Research In People With Binge Eating Disorder, Davy Vancampfort, Simon Rosenbaum, Michel Probst, Joanne Connaughton, Christy Du Plessis, Taisei Yamamoto, Jolien Diedens, Brendon Stubbs

Physiotherapy Papers and Journal Articles

Despite emerging evidence illustrating the benefits of physical activity for people with binge eating disorder, engaging this population in physical activity is challenging. The International Organization of Physical Therapists in Mental Health (IOPTMH) set out to summarize, appraise and strengthen the direction of physical activity endeavors. This process led to the identification of 10 important research questions which are discussed. Addressing these 10 research questions is critical for developing evidence-based approaches for promoting and sustaining an active lifestyle in people with binge eating disorder.

Employment Patterns Of Notre Dame Graduate Physiotherapists 2006–12: Targeting Areas Of Workforce Need, Eleni Bacopanos, Susan Edgar

Physiotherapy Papers and Journal Articles

Background: The Australian physiotherapy workforce is changing both in demographics and service needs. Physiotherapy curriculum and clinical education focus is ideally based on up-to-date knowledge of this changing workforce.

Aim: The aim of this study was to determine the employment patterns of Physiotherapy graduates from The University of Notre Dame Australia (Notre Dame).

Method: An online survey was conducted of Notre Dame Physiotherapy graduates (2006-2012) with a 50% response rate (n=157).

Results: Survey results established the employment location, employment status, healthcare sector, area of practice, salary and employment history of Notre Dame graduates. The results highlighted links between curriculum, clinical …

The Social Experience Of Internet Gamers: A Pilot Study, Kristy L. Carlisle, Charles P. Carrington

Counseling & Human Services Faculty Publications

The purpose of this phenomenological pilot study was to explore the lived social experiences of Internet gamers. Findings highlighted the impact of Internet gaming on social interactions, social functioning, and social identity. The findings in the pilot study related to addiction supported the need for future research into the legitimacy of Internet Gaming Disorder as a mental health issue.

Health Sciences Librarianship Goes Mobile: Using The Ms Surface Pro 2 To Deliver Instruction And To Access Medical Content, Elizabeth Retzel Bucciarelli

Faculty Scholarship - University Library

No abstract provided.

Genome-Wide Profiling Of Histone Modifications (H3k9me2 And H4k12ac) And Gene Expression In Rust (Uromyces Appendiculatus) Inoculated Common Bean (Phaseolus Vulgaris L), Vasudevan Ayyappan, Venu Kalavacharla, Jyothi Thimmapuram, Ketaki P. Bhide, Venkateswara R. Sripathi

Cyber Center Publications

Histone modifications such as methylation and acetylation play a significant role in controlling gene expression in unstressed and stressed plants. Genome-wide analysis of such stress-responsive modifications and genes in non-model crops is limited. We report the genome-wide profiling of histone methylation (H3K9me2) and acetylation (H4K12ac) in common bean (Phaseolus vulgaris L.) under rust (Uromyces appendiculatus) stress using two high-throughput approaches, chromatin immunoprecipitation sequencing (ChIP-Seq) and RNA sequencing (RNA-Seq). ChIP-Seq analysis revealed 1,235 and 556 histone methylation and acetylation responsive genes from common bean leaves treated with the rust pathogen at 0, 12 and 84 hour-after-inoculation (hai), while …

Influence Of Maternal Prior Life Adversity On The Psycho-Neuroendocrine-Immune Profile During Pregnancy, Karen J. Kotz

Dissertations

Pregnancy is accompanied by a multitude of physical and psychological changes. Adaptation to these changes through reduced anxiety and attenuated stress responsiveness is necessary across gestation and into the postpartum period for optimal maternal-infant health. In contrast, exposure to higher amounts of stressors during pregnancy can disrupt neuroendocrine-immune processes required for successful pregnancy outcomes. Evolving evidence demonstrates that exposure to adversity early in life has long-lasting effects on stress response systems that alter stress reactivity during adulthood. Given this evidence, it is posited that women who experience greater pre-pregnancy adversity during their childhood are at greater risk for negative maternal-infant …

Participatory Action Research To Improve Caregiver Education Based On Cognitive Performance Test Results For Persons With Alzheimer's Disease Or Mild Cognitive Impairments, Terrianne Jones

Occupational Therapy Program Student Theses, Dissertations and Capstones

The aim of this study was to make changes to how occupational therapists in a transitional care unit setting provide education about Cognitive Performance Test (CPT) scores to caregivers of those patients with dementia or suspected dementia. Caregiver education for this population is important, as the incidence of persons living with Alzheimer's disease and other dementias is expected to grow dramatically in the coming two decades. This study used a Participatory Action Research (PAR) approach to gather input from occupational therapists and caregivers of patients evaluated with the CPT. Interviews of caregivers indicated that they were unhappy with the education …

Effects Of Aggregated Alpha-Synuclein On Cultured Neuronal Cells, David Freeman

Dissertations

α-synuclein dysregulation is a critical aspect of Parkinson's disease pathology. Recent studies have observed that α-synuclein aggregates are cytotoxic to cells in culture and that this toxicity can be spread between cells. However, the molecular mechanisms governing this cytotoxicity and spread are poorly characterized. Recent studies of viruses and bacteria, which achieve their cytoplasmic entry by rupturing intracellular vesicles, have utilized the redistribution of galectin proteins as a tool to measure vesicle rupture by these organisms. Using this approach, we demonstrate that α-synuclein aggregates can induce the rupture of lysosomes following their endocytosis in neuronal cell lines. This rupture can …

Extended Treatment Window Exists For Improving Sensorimotor Recovery Using Anti-Nogo A Immunotherapy In Adult Rats With Chronic Stroke Deficits, Katherine Marie Podraza

Dissertations

Stroke related death ranks as the fourth most common cause of mortality in the United States. Current therapeutic options following stroke are limited. One potential therapy involves the use of anti-Nogo-A immunotherapy post-stroke. Our laboratory has shown that the administration of this novel treatment results in sensorimotor recovery in adult and aged rats. This therapy has been shown to be efficacious when applied immediately, 24 hours, and 1 week post-stroke in rats with mild to moderate sensorimotor deficits. In addition, recent results suggest that administration of anti-Nogo-A immunotherapy up to 9 weeks after stroke still induces functional recovery and neuroanatomical …

Characterization Of The Effect Of Anti-Nogo-A Antibody Treatment On Sensorimotor Recovery After Traumatic Brain Injury, Stephen Nawara

Dissertations

Estimates indicate that over 5 million Americans are currently living with Traumatic Brain Injury (TBI) related disability. Much effort has been put into enhancing functional recovery with physical therapy and other rehabilitative approaches. These strategies are thought to function by facilitating the brain’s innate capacity for neuroregeneration and neuroplasticity. However, the success of these strategies may be limited due the presence of growth- and plasticity- inhibiting factors expressed in the adult brain.

The presence of the membrane protein Nogo-A has been associated with reduced neurite outgrowth in vitro, identifying it as one such molecule. In addition, rodents treated with antibodies …

Applying The Pharmacists’ Patient Care Process To Immunization Services: A Resource Guide For Pharmacists, Albert Bach, Jeff Goad, Mitchel Rothholz, Brian Wall, Anne Burns, Liza Chapman, Jean-Venable “Kelly” R. Goode, Sheila Seed, Rebecca Snead

Pharmacy Faculty Articles and Research

"This guidance document has been written and formatted to align comprehensive components of a pharmacy-based immunization patient encounter Collect Assess Plan Implement Follow-Up 6 American Pharmacists Association and recommendations from the National Vaccine Advisory Committee (NVAC) the Standards for Adult Immunization Practice with the original framework of the PPCP.5 The colored columns to the right throughout this document are the PPCP steps as they have been published by JCPP, and the main document text describes how to integrate each PPCP step into immunization services."

Compliance To The Consort Statement On Participant Flow Diagrams In Infectious Disease Randomized Clinical Trials, Onyeka P. Godwin, Brandon Dyson, Paul S. Lee, Soon Park, Euni Lee

Pharmacy Faculty Articles and Research

Background: The Consolidated Standard of Reporting Trials (CONSORT) Guidelines were developed to support adequate reporting of randomized controlled trials (RCTs).

Method: A systematic review was conducted including RCTs of infectious diseases published in the top general medical and infectious disease journals in 2010. The level of compliance to flow diagram and its association with the CONSORT endorsement by the journals were evaluated.

Results: A total of 67 studies were included in the analysis and a half of the studies were HIV/AIDS RCTs. About 78% of the studies included the flow diagram and 66% of the studies described …

Drug-Induced Cardiotoxicity Of Oncological Agents: Monitoring Parameters, Prevention, And Future Chemotherapy, Sarah Nguyen, Mary Nguyen, Laura Tsu

Pharmacy Faculty Articles and Research

The goal of this article is to educate pharmacists of the impact of cardiotoxicity on chemotherapy regimens including key cancer agents, monitoring parameters, prevention, and the future of chemotherapy.

Formulation And In Vitro Evaluation Of Niacin-Loaded Nanoparticles To Reduce Prostaglandin Mediated Vasodilatory Flushing, Dustin L. Cooper, Jennifer A. Carmical, Peter C. Panus, Sam Harirforoosh

Pharmacy Faculty Articles and Research

OBJECTIVE: Niacin, activating G-protein coupled receptor (GPR) 109A, stimulates release of vasodilatory prostaglandins (PGs) such as PGE2 which can elicit niacin-associated flushing side effects. Poly-lactic-co-glycolic acid (PLGA) and poly-lactic acid (PLA) are used in nanoparticle (NP) drug delivery to reduce adverse effects and modulate drug release. Our study evaluated the in vitro effects of niacin-loaded PLGA or PLA-NPs on PGE2 expression in whole human blood as a model for niacin-induced flushing.

MATERIALS AND METHODS: NPs were formulated using a solvent evaporation process and characterized by size, polydispersity, zeta potential, drug entrapment, morphology, and drug release. NP in vitro …

Histopathology And Oxidative Stress Analysis Of Concomitant Misoprostol And Celecoxib Administration, Derek E. Murrell, James W. Denham, Sam Harirforoosh

Pharmacy Faculty Articles and Research

Nonsteroidal anti-inflammatory drugs (NSAIDs), non-selective or selective inhibitors of cyclooxygenase (COX-1 and -2), reduce pain and inflammation associated with arthritic diseases. Celecoxib, a COX-2-selective inhibitor providing decreased gastric injury relative to on-selective NSAIDs, is commonly prescribed. Misoprostol, a prostaglandin analog, supplements NSAID-inhibited prostaglandin levels. As concomitant celecoxib and misoprostol administration has been shown to intensify renal adverse effects, this article examined the influence of concomitant administration on hepatic histopathology, oxidative stress, and celecoxib concentration. On days 1 and 2, rat groups (n = 6) were gavaged twice daily (two groups with vehicle and two groups with 100 μg/kg misoprostol). From …