Medicine and Health Sciences Commons^™

Missed Opportunities For The Diagnosis Of Colorectal Cancer, Laura A. Siminoff, Heather L. Rogers, Sonja Harris-Haywood

Biochemistry and Molecular Biology Publications

Objective. To examine patient and medical characteristics which predict a missed diagnostic opportunity (MDO) for colorectal cancer (CRC). Methods. The sample consisted of 252 patients diagnosed with Stages 1–4 CRC who were diagnosed in the prior six months, had experienced symptoms prior to diagnosis, and were not diagnosed through routine screening. Systematic review of all medical records prior to patients’ diagnosis was conducted. An MDO was defined as a clinical encounter where, even in the presence of presumptive CRC symptoms, the CRC diagnostic process is not started. Results. 92 patients (36.5%) experienced an MDO. Almost 80% of alternate diagnoses were …

Interrogating The Venom Of The Viperid Snake Sistrurus Catenatus Edwardsii By A Combined Approach Of Electrospray And Maldi Mass Spectrometry, Alex Chapeaurouge, Md Abu Reza, Stephen P. Mackessy, Paulo C. Carvalho, Richard H. Valente, André Teixeira-Ferreira, Jonas Perales, Qingsong Lin, R. Manjunatha Kini

Biochemistry and Molecular Biology Publications

The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families. In the present study, we investigated the tryptic digest of the venom of the viperid snake Sistrurus catenatus edwardsii by a combined approach of liquid chromatography coupled to either electrospray (online) or MALDI (offline) mass spectrometry. These different ionization techniques proved to be complementary allowing the identification a great variety of isoforms of diverse snake venom protein families, as evidenced by the detection of the corresponding unique peptides. For example, ten out of eleven predicted …

The Impact Of A Community-Based Hiv And Sexual Reproductive Health Program On Sexual And Healthcare-Seeking Behaviors Of Female Entertainment Workers In Cambodia, Siyan Yi, Sovannary Tuot, Pheak Chhoun, Carinne M. Brody, Khimuy Tith, Sopheap Oum

Background: In Cambodia, despite great successes in the fight against HIV, challenges remain to eliminating new HIV infections and addressing sexual reproductive health (SRH) issues in key populations including female entertainment workers (FEWs). To address these issues, the Sustainable Action against HIV and AIDS in Communities (SAHACOM) project has been implemented since late 2009 using a community-based approach to integrate HIV and SRH services. This study evaluates the impact of the SAHACOM on sexual and healthcare-seeking behaviors among FEWs in Cambodia.

Methods: A midterm and endpoint comparison design was utilized. Midterm data were collected in early 2012, and …

National Children's Dental Health Month Poster "Defeat Monster Mouth" (2015), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

National Children’S Dental Health Month - Guidelines For Usage Of The Slogan “Defeat Monster Mouth” (2015), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

National Children's Dental Health Month Activity Book (2015), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Genome Engineering To Create Dominant Alleles In Caenorhabditis Elegans Using Crispr-Cas9 Technology, Abrar Sulaimani

Graduate School of Biomedical Sciences Theses and Dissertations

Many investigators have being using CRISPR-Cas9 as a method of genome engineering because it is easy, accurate and fast. This technique has been used to modify the genomes of a wide variety of organisms, including the nematode Caenorhabditis elegans (C. elegans). The short life cycle and ease of introducing exogenous plasmids make C. elegans an ideal system for advancing this technique. My thesis had two aims that focused on developing methods to create dominant alleles in C. elegans. Genetic modifications like precise deletion and insertions into a locus of chromosome are technically challenging. Additionally, although there are several ways of …

Clinical Guidelines In Practice: How Well Are Primary Care Providers Following National Chronic Kidney Disease Recommendations?, Kaitlyn Edbauer

Senior Honors Projects

Chronic kidney disease (CKD), prevalent in more the 10% of the United States population is a progressive, degenerative disease affecting the renal function of afflicted individuals. In recent decades CKD has gained awareness among clinicians and medical professional due to growing concern for the many complications that arise in patients with CKD. For providers, CKD patient populations pose a significant challenge in terms of quality treatment because of the many associated risk factors and co-morbidities associated with a CKD diagnosis. The KDIGO (Kidney Disease; Improving Global Outcomes) 2012 clinical guidelines for the treatment of CKD were published under the sponsorship …

A Role For Folk Psychology In Animal Cognition Research, Kristin Andrews

Experimentation Collection

If we consider that the field of animal cognition research began with Darwin’s stories about clever animals, we can see that over the 150 years of work done in this field, there has been a slow swing back and forth between two extreme positions. One extreme is the view that other animals are very much like us, that we can use introspection in order to understand why other animals act as they do, and that no huge interpretive leap is required to understand animal minds. On the other extreme we have the view that other animals are utterly different from …

Segregation Of Information About Emotional Arousal And Valence In Horse Whinnies, Elodie F. Briefer, Anne-Laure Maigrot, Roi Mandel, Sabrina Briefer Freymond, Iris Bachmann, Edna Hillmann

Sentience Collection

Studying vocal correlates of emotions is important to provide a better understanding of the evolution of emotion expression through cross-species comparisons. Emotions are composed of two main dimensions: emotional arousal (calm versus excited) and valence (negative versus positive). These two dimensions could be encoded in different vocal parameters (segregation of information) or in the same parameters, inducing a trade-off between cues indicating emotional arousal and valence. We investigated these two hypotheses in horses. We placed horses in five situations eliciting several arousal levels and positive as well as negative valence. Physiological and behavioral measures collected during the tests suggested the …

Compassion As A Practical And Evolved Ethic For Conservation, David Ramp, Marc Bekoff

Conservation Collection

The ethical position underpinning decisionmaking is an important concern for conservation biologists when setting priorities for interventions. The recent debate on how best to protect nature has centered on contrasting intrinsic and aesthetic values against utilitarian and economic values, driven by an inevitable global rise in conservation conflicts. These discussions have primarily been targeted at species and ecosystems for success, without explicitly expressing concern for the intrinsic value and welfare of individual animals. In part, this is because animal welfare has historically been thought of as an impediment to conservation. However, practical implementations of conservation that provide good welfare outcomes …

Histological Sequences Of Long Bone Development In The New Zealand White Rabbits, Yasser A. Ahmed, Eman A. Abdelrahim, Fatma Khalil

Histology Collection

Long bone development occurred through endochondral ossification. The current study investigated the main histological changes associated with the development of humerus from the New Zealand white rabbits. The upper limb or humerus during embryonic (12, 14, 15, 16, 18, 21, 24 and 27 days) and neonatal (3 and 7 days) development was processed for light microscopy. Three stages preceded endochondral ossification; limb bud (mesenchymal cells), cartilage primordia (mesenchymal condensation and differentiation into chondrocytes) and cartilage template (organization of chondrocytes into proliferative and hypertrophic zones) by 12, 14 and 15 days, respectively. At day 16, cartilage template elongated forming a cartilaginous …

Maintaining Ethical Standards During Conservation Crises, Ryan K. Brook, Mark Cattet, Chris T. Darimont, Paul C. Paquet, Gilbert Proulx

Ethics and Conservation Biology Collection

Many species at risk in Canada and globally are at or approaching a crisis, especially where little or nothing consequential is being done to prevent extirpation. Such is the case of endangered boreal caribou (Rangifer tarandus caribou) in southern Alberta, Canada. Expedient but inadequate emergency ‘fixes’ have been experimentally implemented to arrest their decline and potential extirpation, but use of these measures raises important ethical problems. In their study of the effects of killing wolves (Canis lupus) on the Little Smoky woodland caribou population, Hervieux et al. (2014a) employed lethal methods that included shooting a firearm from a helicopter and …

A General Framework For Animal Density Estimation From Acoustic Detections Across A Fixed Microphone Array, Ben C. Stevenson, David L. Borchers, Res Altwegg, René Swift, Douglas M. Gillespie, G. John Measey

Bioacoustics Collection

1. Acoustic monitoring can be an efficient, cheap, non‐invasive alternative to physical trapping of individuals. Spatially explicit capture–recapture (SECR) methods have been proposed to estimate calling animal abundance and density from data collected by a fixed array of microphones. However, these methods make some assumptions that are unlikely to hold in many situations, and the consequences of violating these are yet to be investigated.
2. We generalize existing acoustic SECR methodology, enabling these methods to be used in a much wider variety of situations. We incorporate time‐of‐arrival (TOA) data collected by the microphone array, increasing the precision of calling animal density estimates. …

College Of Nursing, Christie Delfanian, Dave Graves, Karissa Kuhle, Emily Weber

College of Nursing Magazine

Features

Impacting Public Health - SDSU’s role improving the state’s health
[Page] 2 — Students work on Crow Creek reservation.
[Page] 6 — Strengthening Native American families to help youth.
[Page] 8 — Using cultural traditions to help Native Americans.
[Page] 10 — Caring for the mind, body and spirit.
[Page] 11 — College receives Impact Award.
[Page] 12 — Examining smoke-free policies.

Department news
[Page] 14- Eight join college’s faculty.
[Page] 15- Former dean, alums receive honors.
[Page] 16- Minton moves into associate dean role.
[Page] 24- Worth receives college’s distinguished service award.

Student News
[Page]18- DNP students experience …

The College Of Pharmacy, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 Medical Laboratory Science A part of the curricula at South Dakota State since 1948, the program moved under the oversight of the College of Pharmacy July 1, 2014.
[Page] 3 MLS did you know? The program graduates an average of 18 students per year. Since 2012, there also has been an online class for practicing medical techs.
[Page}4 A program first The medical laboratory science program held its first White Coat Ceremony and the charter members of the Rho chapter of the Lambda Tau honor society were inducted Nov. 12, 2014.
[Page] 6 Fall convocation Students gain a …

Adverse Cardiovascular Function Secondary To Inappropriate Exogenous Androgenic Anabolic Steroid Usage In Young Adult Males, Nicholle Rothengass

Physician Assistant Scholarly Project Posters

• In today’s society body image and athletic performance are emphasized and influenced by peers’ perception. The inappropriate use of AAS in young males has steadily increased over the past few decades. The purpose of this study is to determine the long-term effects AAS have upon the cardiovascular system. The review of literature will explore studies that identify long-term abuse of injected AAS, which are used by adult male athletes’ ages 18-40 compared to those equivalent male athletes who have never used any form of drugs or steroids and their effects on the cardiovascular system. The researcher plans to analyze …

Homophobia And Hiv Transmission: A Six-Country Comparative Analysis, Tiernan Middleton

HIM 1990-2015

This interdisciplinary study combines epidemiological data with anthropological theory to investigate the relationship between HIV transmission rates and systemic homophobia. Previous research has illustrated the link between high levels of structural violence and structural stigma to increased risk of diseases such as the link between African-Americans and heart disease. This study investigates the relationship between systemic homophobia and HIV transmission rates. Through operationalizing homophobia into seven distinct factors, I evaluated systemic homophobia in six countries, assigning a score 1-10 to each factor using secondary source aggregation. I compared composite scores, as well as scores in each operationalized factor to HIV …

Virtual Reality Simulation: An Innovative Teaching Tool For Dietetics Experiential Education, Anne Davis

Nutrition Sciences Faculty Publications

This paper investigates the role of virtual reality and web technologies in the field of dietetics education. Within this frame, special emphasis is given on the building of web-based virtual learning environments so as to successfully fulfill their educational objectives. In particular, basic pedagogical methods are studied, focusing mainly on the efficient preparation, approach and presentation of learning content, and specific designing rules are presented considering the hypermedia, virtual and educational nature of this kind of applications. The paper also aims to highlight the educational benefits arising from the use of virtual reality technology in dietetics and study the emerging …

Six Weeks Habituation Of Simulated Barefoot Running Induces Neuromuscular Adaptations And Changes In Foot Strike Patterns In Female Runners, Iman Akef Khowailed, Jerrold S. Petrofsky, Everett Lohman, Noha Daher

College of Health & Human Services (TUN) Publications and Research

BACKGROUND: The aim of this study was to examine the effects of a 6-week training program of simulated barefoot running (SBR) on running kinetics in habitually shod (wearing shoes) female recreational runners.
MATERIAL AND METHODS: Twelve female runners age 25.7±3.4 years gradually increased running distance in Vibram FiveFingers minimal shoes over a 6-week period. The kinetic analysis of treadmill running at 10 Km/h was performed pre- and post-intervention in shod running, non-habituated SBR, and habituated SBR conditions. Spatiotemporal parameters, ground reaction force components, and electromyography (EMG) were measured in all conditions.
RESULTS: Post-intervention data indicated a significant …

Analyses Of Ionizing Radiation Effects In – Vitro In Peripheral Blood 1 Lymphocytes With Raman Spectroscopy, Adrian Maguire, Isabel Vegacarrascal, Lisa White, B. Mcclean, Orla L. Howe, Fiona Lyng, Aidan Meade

Articles

The use of Raman spectroscopy to measure the biochemical profile of healthy and diseased cells and tissues may be a potential solution to many diagnostic problems in the clinic. Although extensively used to identify changes in the biochemical profiles of cancerous cells and tissue, Raman spectroscopy has been used less often for analyzing changes to the cellular environment by external factors such as ionizing radiation. In tandem with this, the biological impact of low doses of ionizing radiation remains poorly understood. Extensive studies have been performed on the radiobiological effects associated with radiation doses above 0.1 Gy, and are well …

Evaluating Self-Efficacy Of Health Behaviors In Bariatric Surgery Patients Through Online Support, Shala Swarm

Regis University Student Publications (comprehensive collection)

Obesity has become an epidemic in the United States leading to numerous health related conditions. Bariatric surgeries are recognized as reasonable treatment options for obesity. However, long term success can be limited without adequate support. Rural areas can be especially difficult to find adequate support, often related to access and distance to care. The main purpose of this project was to analyze changes in perceptions of participants’ ability to engage in health promoting behaviors pre-intervention and post intervention. The intervention was a virtual behavioral support program for post bariatric surgery patients. The main objective was to determine if following participation …

Differential Proteomic Analysis Of Endemic And Sporadic Epstein-Barr Virus-Positive And Negative Burkitt Lymphoma, Nader Kim El-Mallawany, Nancy Day, Janet Ayello, Carmella Van De Ven, Kevin Conlon, Damian Fermin, Venkatesha Basrur, Kojo Elenitoba-Johnson, Megan Lim, Mitchell S. Cairo

NYMC Faculty Publications

BACKGROUND: Burkitt lymphoma (BL) is the most common non-Hodgkin lymphoma in children worldwide and the most common paediatric malignancy in sub-Saharan Africa. The endemic (eBL) and sporadic (sBL) variants have distinct epidemiologic and virologic characteristics. Although gene expression studies have defined the transcriptional profiles of both, their proteomic signatures have not been studied. METHODS: We compared the proteomic expression profiles using differential mass spectrometry-based isotope tag for relative and absolute quantitation (iTRAQ) analysis of a cell line representing Epstein-Barr virus (EBV)+ eBL, EBV+ and EBV- sBL, and EBV+/- normal B cells from healthy donors. RESULTS: In total, there were 144 …

Stop Cautis: A Unit-Based Education And Leadership Bundled Approach, Jennifer Healy Msn, Rn, Ccrn, Jennifer O'Neil Bsn, Rn, Danielle Moody Rn, Leigh Jimmie Bsn, Rn, Anne M. Aquila

Posters

1. The CAUTI Prevention committee recognized a continued opportunity to reduce CAUTI occurrences in the MICU
2. A sub-group developed and implemented an evidence-based educational program which was completed in October 2014
3. The MICU Team has decreased their CAUTI rate from 12 occurrences (Sept. 2013- Aug. 2014) down to 3 occurrences (Sept 2014-Aug 2015)
4. The team continues to use an auditing process and the insertion checklist as ongoing quality improvement

Implementing Cognitive Behavioral Therapy Into Post Cerebral Vascular Accident Rehabilitation: An Occupational Therapy Guideline, Erica Myers, Sarah Peterson

Occupational Therapy Capstones

Strokes are a leading cause of disability in the United States, with approximately 7 million adults currently living with a stroke. The incidence rate of strokes is expected to significantly increase by 2030, which demonstrates a need for this population to receive quality care (Billinger et al., 2014). There is extensive research on how occupational therapists provide skilled interventions for the physical and cognitive deficits of a stroke; however, a gap in the literature exists regarding treatment of the psychosocial impairments an individual may experience post-stroke. Specifically, there is limited research on how to treat post-stroke depression (PSD) and post-stroke …

Occupational Therapy Practitioners' Views On Health And Wellness Promotion Programming: A Qualitative Study, Danielle Nelson-Deering, Haley Pratt

Occupational Therapy Capstones

Purpose: Explore the essence of occupational therapy (OT) practitioners’ perceptions of their experiences with health and wellness programming; to further understand the lack of this type of programming by finding out what their needs are in order to provide it.

Methods: A qualitative, phenomenological study was used to gather data to answer the research questions. Following IRB approval, convenience/snowball sampling was used to access participants and gather data. Five registered occupational therapists participated in this study.

Results: OT practitioners have positive views for health and wellness promotion; however, in order to be successful to OT practitioner must have an internal …

Rehabilitation Pre And Post Mpfl Reconstruction Secondary To Mpfl Tear, Kayla Skersick

Physical Therapy Scholarly Projects

Background and Purpose: The medial patello-femoral ligament (MPFL) is the primary soft tissue structure that withstands forces throughout range of motion (ROM) to prevent the patella from sliding over the lateral femoral condyle and dislocating from the patellar groove. Impaired stabilization and line of pull of the patella can directly affect the patella and the entire kinematic chain during movement. MPFL reconstruction has become the most popular surgical treatment to correct this anomaly when conservative strengthening and biomechanical correcting treatments have failed. This case study evaluates the effectiveness of physical therapy treatment pre-operative and postoperative MPFL reconstruction, and discusses the …

The Effectiveness Of The "Stepping On" Program For Reducing The Incidence Of Falls In The Elderly, Lisa Yonker, Jacqueline Maddock, Kathleen Breuer

Physical Therapy Scholarly Projects

Background: One in three adults greater than 65 years of age have had an accidental fall in their lifetime. In 2012, accidental falls cost the U.S. healthcare system $30.1 billion dollars. Strength, balance, and coordination deficits contribute to an individual experiencing a fall. Studies have shown that community based-exercise programs for older adults can improve strength, balance, and coordination and reduce the risk of falls.

Objective: The purpose of this study was to discover whether participant balance and confidence improved following the completion of the Stepping On program. Also, the study evaluated the effectiveness of Stepping On in …

Hypoglossal Nerve Stimulation Therapy In Obstructive Sleep Apnea, Taylor Fontaine

Physician Assistant Scholarly Project Posters

• Obstructive sleep apnea (OSA) is a disorder that results in loud snoring, gasping respirations, and excessive daytime sleepiness.

• OSA also has the potential to progress to other significant diseases such as hypertension, diabetes mellitus, stroke, and pulmonary hypertension.

• Continuous positive airway pressure (CPAP) has been the first line treatment for OSA since the early 1980’s. Unfortunately, despite the ability of CPAP to significantly improve symptoms of OSA, a large amount of patients struggle to comply with this treatment.

• A new alternative treatment for OSA is hypoglossal nerve stimulation therapy (HGNS), resulting in an increase in muscle …

Effects Of Saw Palmetto On Lower Urinary Tract Symptoms From Benign Prostatic Hyperplasia, Michael Trimble

Physician Assistant Scholarly Project Posters

• Benign prostatic hypertrophy (BPH) is common in older males and can cause lower urinary tract symptoms (LUTS).

• Saw Palmetto, an herbal supplement, is normally implemented as an alternative medication to treat lower urinary tract symptoms associated with BPH.

• The review of literature evaluated studies comparing the effects and outcomes of Saw Palmetto versus commonly prescribed medications such as antiadrenergic agents.

• There are conflicting studies indicating Saw Palmetto’s efficacy on lower urinary tract symptoms and reduction of BPH.

• Saw Palmetto has no side effects, and is available at a low cost when compared to prescribed medications …