Medicine and Health Sciences Commons^™

Critical Self-Reflection Questions For Professsionals Who Work With Grandfamilies, Megan L. Dolbin-Macnab

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

One of the reasons that grandparents raising grandchildren may not receive needed services is because they perceive professionals as being judgmental or holding negative attitudes toward them. As such, it is important for human service professionals to critically examine their opinions and attitudes toward grandfamilies, within the context of larger social structures, for the purposes of identifying those views that might interfere with the delivery of high quality services. This practice brief provides an overview of critical self-reflection questions that can be used, in a variety of ways, for training purposes. By utilizing these critical self-reflection questions, professionals can discover …

Practice Recommendations For Mental Health Professionals: Perspectives From Grandparents And Their Adolescent Grandchildren, Kendra A. O'Hora, Megan L. Dolbin-Macnab

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

Although grandfamilies are consumers of a variety of mental health services, less is known about what these families, particularly the grandchildren, want from practitioners. To gain insight into how practitioners can best meet the needs of grandfamilies, 40 custodial grandmothers and their adolescent grandchildren were interviewed. Results of a qualitative analysis indicated that grandmothers and grandchildren did not make clear distinctions between various types of services and service providers. Grandchildren, in particular, emphasized the need for mental health professionals to facilitate mentoring and to provide opportunities for grandchildren to socialize with other grandchildren who have been through similar circumstances. Grandmothers …

Early Childhood Overweight And Obesity In Multigenerational Households, Chelsea O. Mckinney

GrandFamilies: The Contemporary Journal of Research, Practice and Policy

This study investigates grandmothers’ role in the health of their grandchildren. The relationship between child weight status from ages three to nine and grandmothers’ coresidence up to age nine is examined using data from The Fragile Families and Wellbeing Study, a large nationally representative dataset of urban low-income families in the United States. Logistic regression estimates the association between grandmother coresidence and child unhealthy weight status. Analyses adjust for child and mother characteristics, culture, race/ethnicity, SES, parenting practices, and built environment. Children who have ever lived with a grandmother by age three are at increased odds of unhealthy weight at …

Effects Of Fructose-Derived Advanced Glycation End Products On Acetylation Of Histones In The Brain, Alissa K. Cornacchia, Mackenzie Hall, Melinda E. Lull

Undergraduate External Publications

Objective: The objective of this study was to determine the effects of fructose and their advanced glycation end products (fru-AGES) on histone acetylation in microglia, the immune cells of the brain.

Significance: Fru-AGES primarily form as a result of non-enzymatic reactions between fructose and proteins. One result is inflammation in the brain, which can be directly correlated to increased microglia activity. Microglial activity has been shown to be associated with the acetylation of histones, resulting in a change in transcription of inflammatory genes. Elucidation of a direct link between fructose, fru-AGES and histone acetylation would increase understanding the pathophysiology of …

Impact Of Antimalarial Treatment And Chemoprevention On The Drug Sensitivity Of Malaria Parasites Isolated From Ugandan Children, Patrick Tumwebaze, Melissa D. Conrad, Andrew Walakira, Norbert Leclair, Oswald Byaruhanga, Christine Nakazibwe, Benjamin Kozak, Jessica Bloome, Jaffer Okiring, Abel Kakuru, Victor Bigira, James Kapisi, Jennifer Legac, Jiri Gut, Roland A. Cooper, Moses R. Kamya, Diane V. Havlir, Grant Dorsey, Bryan Greenhouse, Samuel L. Nsobya, Philip J. Rosenthal

Collected Faculty Scholarship

Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites. We characterized ex vivo drug sensitivity and parasite polymorphisms associated with sensitivity in 459 Plasmodium falciparum samples obtained from subjects enrolled in two clinical trials in Tororo, Uganda, from 2010 to 2013. Sensitivities to chloroquine and monodesethylamodiaquine varied widely; sensitivities to quinine, dihydroartemisinin, lumefantrine, and piperaquine were generally good. Associations between ex vivo drug sensitivity and parasite polymorphisms included decreased chloroquine and monodesethylamodiaquine sensitivity and increased lumefantrine and piperaquine sensitivity with pfcrt 76T, as well as increased lumefantrine sensitivity with pfmdr1 86Y, Y184, and 1246Y. …

What's Happening: March 9, 2015, Maine Medical Center

What's Happening

No abstract provided.

Collective Impact Through Public Health And Academic Partnerships: A Kentucky Public Health Accreditation Readiness Example, Angela L. Carman

Health Management and Policy Faculty Publications

In the ever-changing, resource-limited public health environment, the use of partners found in the faculty and students of Colleges of Public Health can provide training, consultation, and technical assistance needed to increase local health department (LHD) workforce capacity to meet new public health demands including national public heath accreditation. This manuscript describes the provision of the backbone support activities of facilitation, data management, and project management by University of Kentucky’s College of Public Health to Kentucky’s LHDs seeking national public health accreditation.

Diversity Speakers Series: Leadership Lessons In Healthcare: From An Orthopedic Surgeon’S Perspective, Katherine Coyner, Pcom Office Of Diversity And Community Relations

Diversity and Inclusion

Program for "Leadership Lessons in Healthcare: From An Orthopedic Surgeon’s Perspective" by Katherine Coyner, M.D., Board Member of The Perry Initiative

Cd47 Deficiency Protects Mice From Diet-Induced Obesity And Improves Whole Body Glucose Tolerance And Insulin Sensitivity, Hasiyeti Maimaitiyiming, Heather Norman, Qi Zhou, Shuxia Wang

Pharmacology and Nutritional Sciences Faculty Publications

CD47 is a transmembrane protein with several functions including self-recognition, immune cell communication, and cell signaling. Although it has been extensively studied in cancer and ischemia, CD47 function in obesity has never been explored. In this study, we utilized CD47 deficient mice in a high-fat diet induced obesity model to study for the first time whether CD47 plays a role in the development of obesity and metabolic complications. Male CD47 deficient and wild type (WT) control mice were fed with either low fat (LF) or high fat (HF) diets for 16 weeks. Interestingly, we found that CD47 deficient mice were …

Differences In Referral And Use Of Complementary And Alternative Medicine Between Pediatric Providers And Patients, Brooke N. Jenkins, Nicole Vincent, Michelle Fortier

Psychology Faculty Articles and Research

Objectives

The goal of this study was to compare pediatric complementary and alternative medicine (CAM) use and pediatric health care provider CAM referral as well as identify predictors of use and referral.

Design

Surveys were administered to 283 parents/caregivers of pediatric patients and 200 pediatric health care providers (HCP).

Setting

This study took place at the Children's Hospital of Orange County (CHOC Children's) in Orange, CA.

Main outcome measures

Caregivers and HCP were provided a list of 32 CAM interventions and asked to indicate which treatments their child had ever used or which they would consider using for their child …

Obesity And Metabolic Phenotypes (Metabolically Healthy And Unhealthy Variants) Are Significantly Associated With Prevalence Of Elevated C-Reactive Protein And Hepatic Steatosis In A Large Healthy Brazilian Population, Sameer Shaharyar, Lara Roberson, Omar Jamal, Adnan Younus, Shozab Ali, Arthur Agatston, Khurram Nasir Baptist Health Medical Group

All Publications

BACKGROUND:Among the obese, the so-called metabolically healthy obese (MHO) phenotype is thought to confer a lower CVD risk as compared to obesity with typical associated metabolic changes. The present study aims to determine the relationship of different subtypes of obesity with inflammatory-cardiometabolic abnormalities.METHODS:We evaluated 5,519 healthy, Brazilian subjects (43 ± 10 years, 78% males), free of known cardiovascular disease. Those with (MRF) were considered metabolically healthy, and those with BMI ≥ 25 kg/m(2) and/or waist circumference meeting NCEP criteria for metabolic syndrome as overweight/obese (OW). High sensitivity C reactive protein (hsCRP) was measured to assess underlying inflammation and hepatic steatosis …

Medical School Watercooler Newsletter - March 8, 2015, Lindsey Lyle

Watercooler Newsletter

This is the March 8, 2015 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

March 19 DSS to Feature Dr. Michael Kotlikoff

Med School Café - Expert Advice for the Community

Karen Simon Recognized for Customer Service Karen

Dr. Sarah Sayner Awarded NIH Grant

The Gas Cylinder, The Motorcycle And The Village Health Team Member: A Proof-Of-Concept Study For The Use Of The Microsystems Quality Improvement Approach To Strengthen The Routine Immunization System In Uganda, Dorothy A. Bazos, Lea R. Ayers Lafave, Gautham Suresh, Kevin C. Shannon, Fred Nuwaha, Mark E. Splaine

Dartmouth Scholarship

Although global efforts to support routine immunization (RI) system strengthening have resulted in higher immunization rates, the World Health Organization (WHO) estimates that the proportion of children receiving recommended DPT3 vaccines has stagnated at 80% for the past 3 years (WHO Fact sheet-Immunization coverage 2014, WHO, 2014). Meeting the WHO goal of 90% national DPT3 coverage may require locally based strategies to support conventional approaches. The Africa Routine Immunization Systems Essentials-System Innovation (ARISE-SI) initiative is a proof-of-concept study to assess the application of the Microsystems Quality Improvement Approach for generating local solutions to strengthen RI systems and reach those unreached …

Building A Hybrid Or In Preparation For Thoracic Endovascular Aortic Repair Program, Lori Fuehrer Rn, Beth E. Frickmann Rn, Cnor

Patient Care Services / Nursing

No abstract provided.

Show Me: Effectively Collaborating With Community Partners To Develop Students' Macro-Practice Skills, Rashida Crutchfield, Simon Funge

Social Work Faculty Publications

No abstract provided.

A Team Approach To Validating Cleanliness Within The Operating Room, Joseph M. Griffin

Patient Care Services / Nursing

No abstract provided.

Multi-Hospital Standardized Orientation For Float Pool Staff Competency, Michelle Reigard Rn, Cnor

Patient Care Services / Nursing

No abstract provided.

Consumption Patterns And Side Effects Of Energy Drinks Among University Students In Palestine: Crosssectional Study, Haleama Al Sabbah, Naim Qamhia, Mustafa Younis

All Works

This study describes the patterns of energy drinks consumption and associated factors among University students in Palestine. A cross-sectional study was conducted at An-Najah National University in Nablus, West Bank-Palestine. The study included 279 students of three colleges: Medicine, Physical Education and Engineering. Data were collected using a 25-item self-administered questionnaire. Energy-drink consumption was significantly higher among male students, as 80.5% of energy-drink users involved in this study was males. It was higher among those with higher monthly expenditure. The most common cause for using energy drinks among users was to stay awake at night (68.6%), while most of those …

P-23 Variations In Microbiota Of Culex (Melanoconion) Ocossa And Culex (Culex) Declaratoracross Periurban And Rural Environments, M. Nelson Starkey

Honors Scholars & Undergraduate Research Poster Symposium Programs

Mosquitoes serve as the primary mode of transmission for many tropical infections such as Venezuelan equine encephalitis virus, dengue virus, and malaria. Therefore, mosquitoes are an important area of study for disease control. This study examined the differences in gut microbiota of Culex melanoconion species across two different habitats: periurban and rural. Mosquitoes were collected from locations around Iquitos, Peru and their gut bacterial DNA was extracted and analyzed. Based on previous studies it is believed that the bacterial flora will differ among mosquitoes reared in different locations.

Prolonged-Acting, Multi-Targeting Gallium Nanoparticles Potently Inhibit Growth Of Both Hiv And Mycobacteria In Co-Infected Human Macrophages., Prabagaran Narayanasamy, Barbara L. Switzer, Bradley E. Britigan

Journal Articles: Pathology and Microbiology

Human immunodeficiency virus (HIV) infection and Mycobacterium tuberculosis (TB) are responsible for two of the major global human infectious diseases that result in significant morbidity, mortality and socioeconomic impact. Furthermore, severity and disease prevention of both infections is enhanced by co-infection. Parallel limitations also exist in access to effective drug therapy and the emergence of resistance. Furthermore, drug-drug interactions have proven problematic during treatment of co-incident HIV and TB infections. Thus, improvements in drug access and simplified treatment regimens are needed immediately. One of the key host cells infected by both HIV and TB is the mononuclear phagocyte (MP; monocyte, …

Erythrodermic Dermatomyositis, Huyenian Nguyen Do, Joshua M. Levin Md, Stephen Purcell Do

Department of Medicine

No abstract provided.

Squamous Cell Carcinoma, Keratoacanthoma-Type Within A Tattoo, Elise Grgurich Do, Nektarios I. Lountzis Md, Stephen Purcell Do

Department of Medicine

No abstract provided.

Posterior Surgical Approach Procedures For Cervical Myelopathy, Pedro H.I. Pohl, Marcel Jun Tamaoki, Luciano M. Rodrigues, Kristen Radcliff, Takashi Yurube, James D. Kang, João Carlos Belloti

Department of Orthopaedic Surgery Faculty Papers

This is the protocol for a review and there is no abstract. The objectives are as follows: The main objective of this review is to assess the effects of laminectomy and fusion versus laminoplasty for multilevel cervical stenosis with myelopathy, on treatment outcomes such as pain, quality of life, functional and neurological improvement, and complication rates. © 2015 The Cochrane Collaboration.

Scalp Arteriovenous Fistula With Intracranial Communication, Stephen Hemperly Do, Richard Mccalin Md, Stephen M. Purcell Do

Department of Medicine

No abstract provided.

Cutaneous Pseudolymphoma Due To Lamotrigine: First Reported Case, Kelly L. Reed Do, Kelly Quinn Do, Anthony J. Gust Md

Department of Medicine

No abstract provided.

Co-Ingestion Of Carbohydrate With Branched-Chain Amino Acids Or L-Leucine Does Not Preferentially Increase Serum Igf-1 And Expression Of Myogenic-Related Genes In Response To A Single Bout Of Resistance Exercise, Rui Li, Maria Pontes Ferreira, Matthew B. Cooke, Paul La Bounty, Bill Campbell, Mike Greenwood, Darren S. Willoughby, Richard B. Kreider

Nutrition and Food Science Faculty Research Publications

This study determined if the co-ingestion of carbohydrate (CHO) with branched-chain amino acids (BCAA) or L-leucine (LEU) preferentially affected serum IGF-1 and the expression of myogenic-related genes in response to resistance exercise (RE). Forty one, college-age males were randomly assigned to 1 of 4 groups: CHO, CHO-BCAA, CHO-LEU, or placebo (PLC). Resistance exercise consisted of 4 sets of leg press and leg extension at 80% 1RM. Supplements were ingested peri-exercise, and venous blood and muscle biopsies were obtained pre-exercise (PRE), and at 30, 120, and 360 min post-exercise. Serum IGF-1 was determined with ELISA, and skeletal muscle mRNA expression of …

Identifying Individual Risk Factors And Documenting The Pattern Of Heat-Related Illness Through Analyses Of Hospitalization And Patterns Of Household Cooling, Michael T. Schmeltz, Grace Sembajwe, Peter J. Marcotullio, Jean A. Grassman, David U. Himmelstein, Stephanie Woolhandler

Publications and Research

Background
As climate change increases the frequency and intensity of extreme heat events researchers and public health officials must work towards understanding the causes and outcomes of heat-related morbidity and mortality. While there have been many studies on both heatrelated illness (HRI), there are fewer on heat-related morbidity than on heatrelated mortality.

Objective
To identify individual and environmental risk factors for hospitalizations and document patterns of household cooling.

Methods
We performed a pooled cross-sectional analysis of secondary U.S. data, the Nationwide Inpatient Sample. Risk ratios were calculated from multivariable models to identify risk factors for hospitalizations. Hierarchical modeling was also …

Determinants Of Adherence To Living On Dialysis For Mexican Americans, Shirley A. Wells

Occupational Therapy Faculty Publications

This study explores perceptions that affect adherence behaviors among Mexican Americans living with dialysis. In-depth narrative interviews were conducted with 15 Mexican Americans with end-stage renal disease (ESRD) living on dialysis, 15 family members, and 6 health care personnel who provided care to them. Four themes emerged: (a) positive influences to adherence, (b) obstacles to adherence, (c) daily activity losses, and (d) fears about living with dialysis. From the findings, the perceptions given for non-adherence with the dialysis regimen ranged from denial of the condition, lack of pre-education, to cultural factors. Those given for adherence included prolonged life, family, and …

The Youth Health Summit, North Carolina: A University-Community Partnership To Promote Health Among Rural Youth, Janie Canty-Mitchell Ph.D., R.N., Musarrat Nahid M.Sc.

National Youth Advocacy & Resilience Conference

Learn how to build partnership with educators, researchers, and practitioners in order to develop educational programs, such as, the Youth Health Summit- a university initiated program undertaken in collaboration with schools and healthcare organizations to promote mental and physical health and create awareness about HIV/AIDS, substance abuse, teen pregnancy, and other hazards among rural middle school students in North Carolina.

March 4, 2015, Communication Disorders & Sciences

Faculty Meeting Minutes & Agendas

Meeting minutes of the March 4, 2015 Faculty Committee meeting.