Medicine and Health Sciences Commons^™

Evidence Of Ventricular Contamination Of The Optical Signal In Preterm Neonates With Post Hemorrhagic Ventricle Dilation, J Kishimoto, M Diop, S De Ribaupierre, Dsc Lee, K St. Lawrence

Medical Biophysics Publications

No abstract provided.

Social Disparities: Household Income In Poverty Stricken Ecuador Affecting Cognitive Function In Children, A. Chamberlain, M. Williams, Jane H. Lassetter

Faculty Publications

Iron deficiency anemia (IDA) is one of the largest nutritional disorders in the world. Approximately 25% of the world’s population has anemia with 50% of those cases being IDA, according to the World Health Organization. The reduced oxygen carrying capacity associated with anemia can have many adverse effects. Many anemia studies have been done on infants but few have been done on school-aged children. A charity organization in Ecuador has been identifying anemia prevalence among children within a suburb of Guayaquil. To further identify possible risks resulting from anemia, a study comparing cognitive function with anemia rates was conducted in …

Integrative Analysis Of Survival-Associated Gene Sets In Breast Cancer, Frederick S. Varn, Matthew H. Ung, Shao Ke Lou, Chao Cheng

Dartmouth Scholarship

Patient gene expression information has recently become a clinical feature used to evaluate breast cancer prognosis. The emergence of prognostic gene sets that take advantage of these data has led to a rich library of information that can be used to characterize the molecular nature of a patient’s cancer. Identifying robust gene sets that are consistently predictive of a patient’s clinical outcome has become one of the main challenges in the field. We inputted our previously established BASE algorithm with patient gene expression data and gene sets from MSigDB to develop the gene set activity score (GSAS), a metric that …

Resting State And Diffusion Neuroimaging Predictors Of Clinical Improvements Following Constraint-Induced Movement Therapy In Children With Hemiplegic Cerebral Palsy., Kathryn Y Manning, Darcy Fehlings, Ronit Mesterman, Jan Willem Gorter, Lauren Switzer, Craig Campbell, Ravi S Menon

Medical Biophysics Publications

The aim was to identify neuroimaging predictors of clinical improvements following constraint-induced movement therapy. Resting state functional magnetic resonance and diffusion tensor imaging data was acquired in 7 children with hemiplegic cerebral palsy. Clinical and magnetic resonance imaging (MRI) data were acquired at baseline and 1 month later following a 3-week constraint therapy regimen. A more negative baseline laterality index characterizing an atypical unilateral sensorimotor resting state network significantly correlated with an improvement in the Canadian Occupational Performance Measure score (r = -0.81, P = .03). A more unilateral network with decreased activity in the affected hemisphere was associated with …

Perception Of Safety, Importance, And Effectiveness Of Vaccinations Among Urban School Employees In Utah, Karlen E. Luthy, Kim E. Thompson, Renea L. Beckstrand, Janelle L B Macintosh, Lacey M. Eden

Faculty Publications

Purpose: School employees are in direct contact with children in confined areas, a setting in which communicable infection can quickly spread. Therefore, it is important for school employees to be fully vaccinated. The purpose of this study is to ascertain the current vaccination status and perceptions of school employees in an urban school district.

Data Sources: The study employed a nonexperimental mixed-method design. School employee participants (N = 1,400) completed a questionnaire to evaluate vaccination status, availability of vaccination records, and vaccination awareness. Participants were randomly selected from 85 schools within one urban school district.

Conclusions: Two common perceptions about …

Nasolacrimal System Aeration On Computed Tomographic Imaging: Effects Of Patient Positioning And Scan Orientation., Craig N Czyz, Thomas S Bacon, Andrew W Stacey, Eva N Cahill, Bryan R Costin, Boris I Karanfilov, Kenneth V Cahill

Ambulatory and Primary Care Articles

PURPOSE: To determine the impact of patient positioning and scan orientation on the appearance of air in the nasolacrimal drainage system on computed tomography (CT) imaging, and the repeatability of the observations.

METHODS: This was a retrospective analysis of CT images for 92 patients.

RESULTS: Air was found to be present more fully in the upright-position group as compared with the supine-position group. Comparing axial and coronal scan orientation, no difference in aeration was found, except for the nasolacrimal duct in the upright-position group.

CONCLUSION: Patient position should be accounted for in diagnostic conclusions and treatment decisions based on CT.

How Women Use Art And Art Therapy To Cope With Breast Cancer: A Systematic Exploration Of Published Literature, Diana C. Barnes

LMU Theses and Dissertations

No abstract provided.

Insertion Of Sequences At The Original Provirus Integration Site Of Mouse Rosa26 Locus Using The Crispr/Cas9 System., Rolen M. Quadros, Donald W. Harms, Masato Ohtsuka, Channabasavaiah B. Gurumurthy

Journal Articles: Genetics, Cell Biology & Anatomy

Targeted transgenic mouse models, where an exogenous gene is inserted into a specified genomic locus to achieve its stable and reliable expression, have been widely used in biomedical research. However, the available methodologies for targeted insertion of sequences require many laborious steps that involve the use of embryonic stem (ES) cells. We recently developed Pronuclear Injection-based Targeted Transgenesis (PITT), a method that uses a recombinase-mediated cassette exchange (RMCE) to enable insertion of sequences at a predetermined genomic locus, such as ROSA26. The PITT technique uses fertilized eggs (instead of ES cells) collected from 'seed mice' that contain the RMCE landing …

Investigation Of The Best Model To Characterize Diffuse Correlation Spectroscopy Measurements Acquired Directly On The Brain, K Verdecchia, M Diop, K St. Lawrence

Medical Biophysics Publications

No abstract provided.

Teaching Health Centers: A Promising Approach For Building Primary Care Work Force For The 21 St Century, Leighton Ku, Fitzhugh Mullan, Christine Cerrano, Zoe Barber, Peter Shin

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

No abstract provided.

Refining And Improving The Methodology For The National Health Security Preparedness Index, Glen P. Mays

Health Management and Policy Presentations

This first meeting of two newly reconstituted Working Groups for the National Health Security Preparedness Index Program examined opportunities for improving and refining the Index's measurement, scaling, weighting, and aggregation methodologies. Methodological improvements will enhance the Index's utility for education, planning, policy development, and quality improvement efforts focused on improving national preparedness and resiliency for large-scale health threats.

Creating A Student -Run Clinic In Allentown, Kirk Jeffers

USF-LVHN SELECT

No abstract provided.

Ed Hospital Medicine Observation Project: A Quality Improvement Initiative, Rachel Appelbaum Bs

USF-LVHN SELECT

No abstract provided.

The Challenges Of Medical School As Told Through Narrative, Sasha Yakhkind

USF-LVHN SELECT

No abstract provided.

Application Of Pre-Participation Screening Guidelines To Novice Masters Endurance Athletes (Poster), Justin R. Abbatemarco Ms, Martin E. Matsumura Md, Courtney Bennett Do, Adrian Bell, Laura M. Dunne Md

USF-LVHN SELECT

No abstract provided.

Targeting Egf-Receptor(S) - Stat1 Axis Attenuates Tumor Growth And Metastasis Through Downregulation Of Muc4 Mucin In Human Pancreatic Cancer., Parthasarathy Seshacharyulu, Moorthy P. Ponnusamy, Satyanarayana Rachagani, Imayavaramban Lakshmanan, Dhanya Haridas, Y Yan, Apar Kishor Ganti, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

Transmembrane proteins MUC4, EGFR and HER2 are shown to be critical in invasion and metastasis of pancreatic cancer. Besides, we and others have demonstrated de novo expression of MUC4 in ~70-90% of pancreatic cancer patients and its stabilizing effects on HER2 downstream signaling in pancreatic cancer. Here, we found that use of canertinib or afatinib resulted in reduction of MUC4 and abrogation of in vitro and in vivo oncogenic functions of MUC4 in pancreatic cancer cells. Notably, silencing of EGFR family member in pancreatic cancer cells decreased MUC4 expression through reduced phospho-STAT1. Furthermore, canertinib and afatinib treatment also inhibited proliferation, …

Prevalence Of Obesity And Estimated Medical And Work Loss Costs Attributable To High Bmi: The Baptist Health South Florida Employee Study, Khurram Nasir, Emir Veledar, Chukwuemeka Osondu, Ehimen Aneni, Oluseye Ogunmoroti, Sankalp Das, Maribeth Rouseff, Thinh Tran, Don Parris, Leah Holzwarth, Henry Guzman, Theodore Feldman, Michael Ozner, Jonathan Fialkow, Bernie Fernandez, Jack Ziffer, Arthur Agatston

All Publications

No abstract provided.

Targeting Tumor-Initiating Cells: Eliminating Anabolic Cancer Stem Cells With Inhibitors Of Protein Synthesis Or By Mimicking Caloric Restriction., Rebecca Lamb, Hannah Harrison, Duncan L Smith, Paul A Townsend, Thomas Jackson, Bela Ozsvari, Ubaldo E. Martinez-Outshoorn, Md, Richard Pestell, Anthony Howell, Michael P. Lisanti, Federica Sotgia

Kimmel Cancer Center Faculty Papers

We have used an unbiased proteomic profiling strategy to identify new potential therapeutic targets in tumor-initiating cells (TICs), a.k.a., cancer stem cells (CSCs). Towards this end, the proteomes of mammospheres from two breast cancer cell lines were directly compared to attached monolayer cells. This allowed us to identify proteins that were highly over-expressed in CSCs and/or progenitor cells. We focused on ribosomal proteins and protein folding chaperones, since they were markedly over-expressed in mammospheres. Overall, we identified >80 molecules specifically associated with protein synthesis that were commonly upregulated in mammospheres. Most of these proteins were also transcriptionally upregulated in human …

Do Modifiable Cardiovascular Risk Factors Differ By Rural Classification In Women Who Enroll In A Weight Loss Intervention?, Dieu-My Tran, Carol H. Pullen, Lani M. Zimmerman Patricia, A. Hageman University Of Nebraska

Nursing Faculty Research

PURPOSE: If clinicians and researchers are aware of specific cardiovascular risks associated with women's rural status, whether it be large or small/isolated rural areas, it may help in developing more relevant rural resources. The purpose of this study was to examine whether there were differences in modifiable cardiovascular risk factors of overweight and obese rural women living in large or small/isolated rural areas. SAMPLE: This secondary analysis examined baseline cross-sectional data from the "Web-based Weight Loss and Weight Maintenance Intervention for Older Rural Women" clinical trial. Analysis included data from 299 rural Midwestern women, ages 40-69 years with a baseline …

The Relationship Between Hearing Status And Cognitive Performance And The Influence Of Depressive Symptoms In The Older Adult, Julie A. Daugherty

USF Tampa Graduate Theses and Dissertations

Hearing loss and cognitive impairment are significant health problems, threatening the independent function of older adults. While there appears to be a strong relationship between the two conditions, the mechanisms underlying this association are complex and are not fully elucidated.

The purpose of this secondary analysis was to explore the relationship between hearing ability and cognitive performance in older adults. In addition, this study attempted to examine the role of depressive symptoms in the relationship between hearing loss and cognitive performance. Comprehensive measures of peripheral hearing, central auditory processing and cognitive performance were utilized to examine these relationships in a …

Optimization And Standardization Of Doctor Preference Cards For Laparoscopic Cholecystectomy At Lehigh Valley Hospital Network, Chris Pothering

USF-LVHN SELECT

No abstract provided.

Transforming Surgical Care To Achieve Better Health, Better Care & Better Cost: Geriatric Hip Fractures., Aresh Ramin Ms1

USF-LVHN SELECT

No abstract provided.

"Participatory Health Care: Patient Perceptions Of Community Resources", Kyle Correll

USF-LVHN SELECT

No abstract provided.

Vulnerable In The Valley: Assessing Homelessness Prevalence In The Lvhn Patient Population, Yasir Abunamous Ms

USF-LVHN SELECT

No abstract provided.

Establishing Pre-Admissions Testing Guidelines At Lehigh Valley Health Network, Shawn Palmeri Ms1

USF-LVHN SELECT

No abstract provided.

Breastfeeding And Baby Friendly, Emma Qureshy Ms1

USF-LVHN SELECT

No abstract provided.

Needs Assessment: Current And Future Women Physicians Of The Lehigh Valley Health Network Executive Summary, Kanchi Batra Ba

USF-LVHN SELECT

No abstract provided.

How Is The Incidence And Recovery From Concussion Affected By Age, Gender, Sport, And Prior Concussion?, Sven Oman

USF-LVHN SELECT

No abstract provided.

Patient Satisfaction: Introducing Two Novel Methods Of Collection, Keith O'Brien, Ian T. Mark

USF-LVHN SELECT

No abstract provided.

Incorporating Personal Values Into Innovative Curriculum Development, Ian Osburn

USF-LVHN SELECT

No abstract provided.